Faculty of MedicineFaculty of MedicineAin Shams UniversityAin Shams University

Postgraduate StudiesPostgraduate Studies

Diploma of Science in Medical

Microbiology and Immunology Program Code: (MI900)

الطبية فى الدبلومدرجة الميكروبيولوجيا والمناعة

Program Guide and Logbook

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C a n d i d a t e C u r r i c u l u m v i t a e

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[telephone no] [mobile no][mailing address]

[email address][postcode]

Experience[organization] [your present job title][start date][location][responsibilities]

[organization]

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[previous job title][start and end date][location][responsibilities][organization] [previous job title][start and end date][location][responsibilities]

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Training[any other training that will be useful in your job]

Filled by post graduate authorities

Date of Registration

First semester _______________________

Second semester _______________________

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TABLE OF CONTENTS:Page

I – Welcome StatementII - Mission StatementIII – Senior supervisor and affiliated departments and HospitalsIV – Program specifications 1 - Basic Information 2 - Professional Information 3 - Academic standards 4 - Curriculum structure and contents

5 - Programme courses: Medical Biochemistry Medical parasitology Fundamentals of Medical Microbiology and Immunology

and Basics of Infection Control Systemic and Applied Medical Microbiology and

Immunology and Infection Control 6. Programme admission requirements: 7- Regulation for progression and programme completion 8- Appendix: course specifications

V - General informationVI – Your log book 1 - Introduction 2 - Supervisors, Trainers and/or Educators 3 - Tables for training records 4 – Log book previewVII - Head of department approval for the exam entry

Detachables forms:

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VIII – Thesis follow upIX - Evaluation forms

I – WELCOME STATEMENT:The Department of Medical Microbiology and Immunology welcomes you to

the Master of Science Degree in Medical Microbiology and Imunology. As a department we are committed to medical student education and continuously strive to improve your educational experience.This handbook presents information guide and logbook activity of the Master of Science Degree in Medical Microbiology and Immunology administered by the Medical Microbiology and Immunology Department, Faculty of Medicine, Ain Shams University.

II - MISSION STATEMENT:The mission of the Faculty of Medicine, Ain Shams University is

• The preparation of a competent graduate, who is able to compete on both national and regional levels, capable of life long learning, training and tutoring, while adhering to the codes of practice of medical health services and ethics.

• The college as well, seeks continuous development of programs and courses. It also enhances expansion of applied scientific research and health programs for community services and environmental development.

The mission of this degree is to prepare a trained graduate with managerial and technical skills in the field of Medical Microbiology and Immunology, capable of providing health education and participating in infection control and prevention at hospital and community basis.

III – SENIOR SUPERVISOR AND AFFILIATED DEPARTMENTS AND HOSPITALS

SENIOR SUPERVISORs

Prof. Ossama RasslanProf. Nehal Anwar FahimE-mail:orasslan@gmail.com nehal.fahim@gmail.com

AFFILIATED DEPARTMENTS AND HOSPITALS

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Department of Medical Microbiology and Immunology Department of Medical Biochemistry and Molecular Biology Department of Parasitology Accredited training centers:

o Central Labs of Ministry of Healtho Microbiological Lab of Abbasia Fever Hospitalo Microbiological Lab of Abbasia Chest Hospital

IV – PROGRAM SPECIFICATIONS

A- Basic Information1. Programme title:

Master of Science in Medical Microbiology and Immunology2. Programme type: Single Double Multiple3. Faculty

Ain Shams University – Faculty of Medicine4. Department

Department of Medical Microbiology and Immunology5. Assistant co-ordinator

Dr. Eman Hussein6. Co-ordinator

Prof.Maha Fathy7. Last date of programme approval: July 2009

B- Professional Information1. Programme aims:On completion of the programme, the candidate will have acquired:

sufficient knowledge and skills to start professional careers as specialist in the field of medical microbiology and immunology

basic teaching skills of medical microbiology and immunology capability to participate in supervised or team research

2. Intended learning outcomes (ILOs):a. Knowledge and understanding:By the end of the program the candidate will be able to:

a1 - explain basic biology of medically important bacterial, viral, and fungal agents.a2 - explain pathogenic mechanisms involved in infection process and the role of host response in immunopathology.

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a3- outline the principles of epidemiology, clinical presentation, and management of infections. a4- recognize the principles of immunity and immunological phenomena which help to understand the pathogenesis and laboratory diagnosis of infectious and non infectious diseasesa5- Understand the principles of laboratory techniques in the field of medical bacteriology, virology, mycology and immunologya6- Recognize potential community-acquired and health care associated infections and the role of environmental factors.

b. Intellectual capabilities:By the end of the programme the candidate will be able to:

b1 - Formulate a systematic approach for laboratory diagnosis of medically important microorganismsb2 - Correlate the clinical picture with laboratory information to help the physician in establishing the appropriate antimicrobial treatment, prevention and control measures. b3- Perform risk assessment for all procedures undertaken in the laboratoryb4- Critically evaluate information and data from a variety of sources, to interpret quantitatively and qualitatively scientific information, and to explain complex scientific ideas in written, visual and oral forms.

c. Professional and practical skills:By the end of the programme the candidate will be able to:

c1-Process all routine specimens received in the laboratory.c2-Carry out tests necessary for full identification of medically important viral/bacterial/fungal pathogens c3-Perform current techniques for antimicrobial susceptibility testing with appropriate quality control. c4- Perform and interpret immunological and serological tests.c5- Operate routine and sophisticated instruments in the laboratory.c6- Apply the good laboratory practices and biosafety measures in medical microbiology lab

d. General and transferable skills:By the end of the programme the candidate will be able to:

d1- Study skills of reading, noting, recall and essay/report writing.

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d2- Gain competence in the use of IT skills including e-mail, word processing, spreadsheets, presentation software, use of the Internet and on-line library facilities. d3-Develop the ability to work independently. d4- Develop interpersonal skills, including team-working. d5- Develop the ability to plan, organize and prioritize work activities. d6- Develop skills of written, oral and visual presentation.

3. Academic standards: (Benchmarks) Academic reference standards guided by University of Arkansas Graduate Program, USA Curriculum for higher specialist training in medical microbiology and

virology, The Royal College of Pathologists, UK

4. Curriculum structure and contents:4a- Programme duration: two academic years (4 semesters)4b- Programme structure:

المناهج

الدراسية الكودالمقرراتالساع

اتالمعتمدة

متطلباتالعلمي الكلية البحث أساسيات دورة

األول حيويه الجزء MI90013كيمياء

MI90023طفيليات

الثاني الجزء

الميكروبيولوجيا. 1 اساسيات

والمناعة الطبيةالعدوى لمكافحة العامة والمبادئ

MI90036

والتطبيقات. 2 التصنفيات

فى العمليةالطبية الميكروبيولوحيا علم

والمناعةوالعدوى ومكافحة

MI900411

المقرراتاالختيارية

المقررات بين من واحد مقررE90341األتية:

9

الطب مهنة أخالقياتالعلمي والبحث

الطبي اإلحصاء

E9009

كراسة6األنشطة

30المجموع

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5. Programme courses:a. CompulsoryCode Course title No. of hours

L P F SDL

MI9001 Medical Biochemistry and Molecular Biology 35 20

MI9002 Medical Parasitology 30 30

MI9003Fundamentals of Medical Microbiology and Immunology and Basics of Infection Control

75 30 -

MI9004

Systemic and Applied Medical Microbiology and Immunology and Infection Control

105 90 60

L: Lecture, C: Clinical, F: field and SDL: Self directed learningb. ElectiveCode Course title No. of hours

L P F SDLE9034 Medical and Research EthicsE9009 Medical and research Statistics6. Programme admission requirements:

:-6 (المادة الماجستير) : درجة على للحصول الطالب لقيد يشترط1 - إحدى من والجراحة الطب في البكالوريوس درجة على ً حاصال يكون أن

معادلة درجة على أو العربية مصر جمهورية جامعات2( االمتياز- ( التدريب سنة أمضى قد يكون أنالعمل- 3 جهة موافقةالمستندات- 4 واستيفاء األجهزة واستهالك التدريب ومصاريف الرسوم تسديد

الملحق ( في ) 1المطلوبةالثاني- 5 الجزء امتحان دخول قبل دراسيين فصلين لمدة للدراسة التفرغ

لدرج ) :1ملحق ( اإللتحاق طالب التالية :-ة يقدم األوراق الماجستيرإلتحاق- 1 طلبالبكالوريوس - 2 شهادةاإلمتياز- 3 شهادةرسمي- 4 مستخرج أو الميالد شهادةالتجنيد - 5 من الموقف

المطلوب - 6 والتفرغ التسجيل على العمل جهة موافقةجديدة 6عدد - 7 فوتوغرافية صوركما - 8 النفقات تحمل جهة ويحدد السفارة موافقة الطالب يقدم للوافدين بالنسبة

صحية شهادة يقدم

7. Regulation for progression and programme completion

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يوليو ): 8مادة ( أول من تبدأ السنة في واحدة مرة للماجستير التسجيل يتم عام كل من أكتوبر شهر في الدراسة تبدأ أن على أغسطس أخر قبول 0حتى ويجوز

ديسمبر أخر نوفمبرحتى أول من الفترة في والوافدين والمعيدين النواب تسجيلالمطلوبة الدراسة فترة إنقضاء بعد إال األول الجزء إمتحان بدخول لهم يسمح أال .على

كل ): 9مادة ( مدة دراسيين فصلين على جامعى عام كل فى الدراسة توزع . فبراير . منصف فى الثانى ويبدا أكتوبر أول فى االول يبدا ً اسبوعا عشر خمسة منهما

للفصل . التسجيل يتم و اسابيع ستة لمدة مكثف صيفى دراسى فصل تنظيم معالمقررات حسب الشروط إستيفاء بعد االقل على بدايته من اسبوعين قبل الدراسى

عن. الواحد الفصل فى الدراسى العبء يزيد أن والينبغى ساعات 6المسجلة الدراسى. الفصل بداية من اسبوعين خالل المقررات تعديل للطالب ويجوز معتمدة

.( المقرارت( احد من اسابيع سته خالل االنسحاب له يجوز كما االضافة او بالحذف فيه ً راسبا احتسابه .دون

) أربعة: ) 11مادة هى الماجستير أو الدبلوم درجة على للحصول الدراسة مدة ( ) ً برنامجا الطالب فيها يجتاز جزئين على دراسية فصول أربعة ً شهرا وعشرون

خاللها ويستوفى الرابع بالباب الموضحة المعتمدة للساعات طبقا ً متكامال ً تدريبيامتابعة كتيب فى منة إستيفاء األنشطة المطلوب قبل اإلمتحان بدخول له يسمح وال

البرنامج من جزء كل في منة المطلوب أرباع 0ثالثة) دراسي ) :12مادة فصل األول الجزء والماجستير الدبلوم في الدراسة واحد مدة

في للدراسة لإلنتقال بالكامل فيه النجاح يشترط وال ً إمتحانا الطالب بعدها يجتاز . الطالب تفرغ يتطلب الثاني والجزء الثاني دراسيين للتدريبالجزء فصلين بأحد لمدة

الكلية من المعتمدة المراكز أو .المستشفيات) شكل ) : 13مادة على الرسالة موضوع بتسجيل الماجستير لدرجة الدارس يقوم

يناقش أن ويجوز األقل على واحد دراسي فصل إستيفاء بعد عملي أو نظري بحثشهور ستة بعد التسجيل رسالتة مقررات من فى نجح قد يكون أن على األقل على

درجا لها يخصص وال الثاني الجزء إمتحان دخول وقبل بالكامل األول 0ت الجزءالرسالة ) : 14مادة ( تسجيل قبل الجامعة متطلبات بإستيفاء الماجستير دارس يقوم

الثاني الجزء إمتحان دخول قبل الكلية الحصول و .ومتطلبات هي الجامعة متطلبات) بمجموع اإلنجليزية اللغة في التويفل شهادة ) 450على ومتطلبات األقل على درجة

مجال في بالكلية العليا الدراسات لجنة من معتمدة دورات حضور هي مناهجالكليةالعلمى . البحث اللجنة تحددها خاصة إختبارات بإجتياز أو الطبى واإلحصاء) بتسجيل ): 15مادة الماجستير درجة إستكمال الدبلوم درجة على للحاصلين يجوز

على ويحصل الدبلوم درجة على الحصول من سنوات أربع خالل الماجستير رسالة . بنجاح الرسالة ومناقشة والكلية الجامعة متطلبات إستيفاء بعد الدرجة

) معتمدة ): 16مادة ساعة ثالثون والماجستير الدبلوم لدراسة المعتمدة الساعاتلكتيب ساعات ست منها يخصص األقل األنشطة على ساعات متابعة ست وتشمل

الثاني للجزء األقل على ساعة عشرة وثماني األول للجزء األقل إليها على ويضاف . الماجستير فى للرسالة ساعات ست

) أربع ): 22مادة العالى والدبلوم سنوات ثالث المهنى الدبلوم لدرجة القيد مدة

خمس وللدكتوراه سنوات أربع وللماجستير سنوات سبع الزمالة ودبلوم سنواتلجنة موافقة وبعد الكلية مجلس طلب على ً بناءا الجامعة لمجلس ويجوز سنوات

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جميع من سنوية تقارير إلى ً وإستنادا القسم مجلس طلب بعد بالكلية العليا الدراساتواحد عام بإضافة السماح الطالب على من المشرفين سنوات ثمان أقصى وبحد

. الدكتوراه درجة على للحصول القيد تاريخوالماجستير ): 24مادة ( العالى للدبلوم النهائى االمتحان درجات درجة 1200مجموع

للدكتوراه 300منها النهائى االمتحان درجات ومجموع األول للجزء درجة 1500درجة. 300منها الف المعدل اليها ويضاف وجد إن األول للجزء يوازى صدرجة بما التراكمى لىو 300 والماجستير العالى للدبلوم للدكتوراه 400درجة درجة

) إمتحان ): 25مادة ويعقد عام كل من ونوفمبر أكتوبر في األول الدور إمتحان يعقد . عام كل من ومايو أبريل فى الثاني الدور

) الحصول ): 26مادة بعد والماجستير العالى الدبلوم من مادة كل فى النجاح يكونمواد% 60على فى النجاح ويكون مجتمعة المادة لجان لكل الكلية الدرجة من

على الحصول بعد درجة% 60الدكتوراه والشفوي من واالكلينيكى والعملي التحريري. حدة على كل

التسجيل): 29(مادة إعادة العليا الدراسات لطالب يمكن القيد مدة إستنفاذ حالة فى . إعادتهما ويجب الرسالة أو األول الجزء فى بالنجاح يعتد وال أخرى مرة

تمنحها): 30مادة ( خاصة مهارة فى خبرة شهادات هى العليا المهنية الشهاداتويجتاز مايعادلها أو الدكتوراه أو الماجستير أو الدبلوم درجة على للحاصلين الجامعة

فى موضح هو كما شهور ستة عن تقل ال مدة فى ًً خاصا ً تدريبيا ً منهجا فيها الطالب. مهنية خبرة شهادة الطالب بعدها يمنح السادس الباب

Assessment Schedule and Weighing of Assessments

Item Mark

Poin

ts

GPA

scor

e

ب

حالةالطال

Stud

ent

stat

e

During semeste

r

End of semeste

rTotal

First semester (If present) 100 300 400Second semester 100 100Third semester 100 100Fourth semester Final exam

Written 900 900Oral

Practical Total 300 1200 1500

للنقاط: طبقا الطالب درجات تعادل التالى ملحوظة الوجه على : 4:فأكثر % 90 -1

نقاط

A

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أقل% 85من- 2 حتى %90من

:3.67 نقاط

A-

أقل% 80من -3 حتى%85من

:3.33 نقاط

B+

أقل% 75من -4 حتى%80من

:3.00 نقاط

B

أقل% 70من -5 حتى%75من

:2.67 نقاط

B-

أقل% 65من -6 حتى%70من

:2.33 نقاط

C+

أقل% 62من- 7 حتى%65من

:2.00 نقاط

C

أقل% 60من -8 حتى%62من

:1.67 نقاط

C-

من -9 Fصفر:%60أقلوالماجستير العالى للدبلوم النهائى االمتحان درجات منها 1200مجموع درجة

للدكتوراه 300 النهائى االمتحان درجات ومجموع األول للجزء منها 1500درجة درجة300 . الف المعدل إليها ويضاف وجد إن األول للجزء يوازى صدرجة بما التراكمى 300لى

و والماجستير العالى للدبلوم للدكتوراه 400درجة . درجةالفصلى ( المعدل حساب نقاط) GPAويتم ضرب حاصل مجموع أساس على

المعتمدة الساعات على ً مقسوما المعتمدة ساعاته عدد فى ً مضروبا مقرر كل . حساب يتم كما الدراسى الفصل فى الطالب درسها التى المعدل للمقررات

للطالب ( حصل) CGPAالتراكمى التى النقاط ضرب حاصل مجموع أساس علىمجموع على ً مقسوما المعتمدة ساعاته عدد فى ً مضروبا مقرر كل فى الطالب عليها

. الكلية المعتمدة الساعاتمن مجموعة أو مادة فى الرسوب حالة الدبلوم مقررات الفى فى

الدكتوراه والماجستير أ . أو فقط المجموعة أو المادة فى اإلعادة حساب يتم ويتمله فيحسب رسوبة تكرر إذا أما فقط إعادة أول فى عليه يحصل الذى الفعلى التقدير

تقدير النجاح اى% (60عند اى 1.67فقط .)C-نقاط

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Appendix: Course SpecificationsMedical Biochemistry and Molecular Biology Course SpecificationsAin Shams University Faculty of Medicine

Course specifications

Programme(s) on which the course is given: Master of Science in Medical Mcrobiology and Immunology

Major or minor element of programmes: Major

Department offering the programme: Medical Microbiology and ImmunologyDepartment offering the course: Medical Biochemistry and Molecular BiologyAcademic year / Level: 1st semester

Date of specification approval ………………………………………..

A- Basic InformationTitle: Medical Biochemistry and Molecular BiologyCode: MI9001Credit Hours: 3Lectures: 35 Practical: 20 Total: 55

Co-ordinatorProf Nora El-Kholy

B- Professional Information

1 – Overall aims of course: help the candidate to Acquire core knowledge in the field of medical biochemistry, both at

cellular and molecular level, relevant to human health and disease Acquire a thorough understanding of the basic principles of molecular

biology and the tools of DNA technology in order to be able to read and interpret scientific papers and to interpret experimental data and diagnostic laboratory results in molecular biology.

2- Intended learning outcomes (ILOs) from the course:

A- Knowledge and understanding

By the end of the course the candidate will be able to:

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a1- Explain the methods of classification and regulation of enzymes as well as kinetics of enzymes, enzyme inhibitors, and diagnostic utility of enzymes. a2- Describe the metabolic pathways of carbohydrates, their energetics, their sites, and the ways of their regulation.a3- Compare exergonic and endergonic reactions, and define ATP sources and functions in the living cell a4- Describe the components of mitochondrial ETC and their inhibitors. a5- Describe membrane architecture and different cross-membrane signaling pathwaysa6- Understand the structure, function and organization of human genomes a7- Describe the main principles of methods for preparation and extraction of DNA and RNA.a8. Understand the main principles of methods for DNA amplification (PCR, RT-PCR, Real-time PCR, etc.)a9- Identify the main principles of methods for DNA sequencinga10- Describe the main principles of DNA and RNA blottinga11- Understand the concepts of recombinant DNA technology a12- Understand the applications of molecular biology techniques in the diagnosis, species and strain differention of microorganisms. a13- Understand the applications of molecular biology techniques in genetic testing, in paternity testing, studying drug resistance, and vaccine and drug development. a14- Describe the molecular basis of cancer, and role of telomerase and apoptosis in tumorogenesis

b- Intellectual skills

By the end of the course the candidate will be able to:

b1- Integrate basic molecular biology facts with microbiological data.b2- Identify the appropriate molecular biology technique required for diagnosing infectious diseases. b3- Analyse and interpret the results of molecular biology techniques. b4- Identify tumor-associated genetic defects related to viral infections.

c- Professional and Practical skills

By the end of the course the candidate will be able to:

c1- Incorporate new molecular biology knowledge and tools into research projectsc2- Use the computer to retrieve and compare molecular biology data

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c3- Solve any subject-related problems provided by staffc4- Apply methods to prevent contamination of the lab and equipments.c5-Follow proper method of disposal of biohazardous samples (infectious, carcinogenic, etc.).c6- Interpret the results of DNA sequencing c7- Interpret the results of PCR and RT-PCR, site-directed mutagenesis, and DNA finger printing

d- General and transferable skills

By the end of the course the candidate will be able to:

d1- develop the skills of working in teams d2- develop appropriate relationships with patient and familyd3- Use basic computing skills and internet to follow electronic lectures d4- Communicate relevant information with teaching staff and colleaguesd5- Search gene and protein Database.d6-Use molecular biology software.

3- Course contents:

Contents No of hoursL P T SDL

Introduction to Biochemistry 1

Carbohydrate metabolism 4Bioenergetics 4Enzymes 4Biological Membranes and Signal transduction 4Gene and Genomes. Structure of DNA and RNA, DNA Replication and RNA Transcription

8

Cell Cycle Regulation and Cancer (Oncogenes and Tumor suppressor genes) 2

Apoptosis 2Cell aging and Telomerase 2Regulation of gene expression 2Gene therapy 2Recombinant DNA technology 4

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Molecular biology techniques ( Extraction of DNA & RNA, PCR and RT-PCR , Blotting techniques and Hybridization techniques)

6

DNA sequencing 2Branched DNA technology 2DNA finger printing 4Site directed mutagenesis 2

6 -- List of References

6.1- Course Notes (paper and / or electronic)Lectures notes and Practical Biochemistry book provided by the staff of Medical Biochemistry and Molecular Biology Department. 6.2- Essential Books (Text Books) USMLE Road Map Biochemistry, Macdonald R, McGraw-Hill Medical Pub.Textbook of Biochemistry with Clinical Correlations, Devlin TM, Wiley-Liss, Inc. Pub.

6.3- Recommended Books Lippincott's Illustrated Reviews: Biochemistry, Champe PC, Lippincott

Williams & Wilkins Pub.

Harper's Illustrated Biochemistry, Robert K. Murray RK, Granner DK, Mayes PA and Rodwell VW, McGraw-Hill Medical Pub.

Lehninger Principles of Biochemistry, Nelson DL and Cox MM, Freeman Pub.

Biochemistry lecture notebook, Berg JM, Tymoczko JL and Stryer L, Freeman Pub.

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Medical Parasitology Course Specifications

Ain Shams University Faculty of Medicine

Course specificationsProgramme: Master degree Of Medical Microbiology and Immunology

Major or minor element of programmes: Major

Department offering the programme: Medical Microbiology and ImmunologyDepartment offering the course: Medical Parasitological Department.

Academic year / Level: Master First Semester

Date of specification approval: July 2009

A- Basic Information

Title: Medical Parasitology Code: MI9002Credit Hours: 3 creditsLecture: 30 Practical: 30Total: 60 hoursCoordinator: Prof. Laila El Hoseiny

B- Professional Information

1 – Overall aims of course: help the candidate to

Acquire basic knowledge of Medical Parasitology including Helminthology, and Protozoology

Acquire practical skills and experience in the laboratory diagnosis of parasitic infections.

2- Intended learning outcomes (ILOs) from the course:

a- Knowledge and understanding

By the end of the course the candidate will be able to:

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a1. Identify parasitic infections of major significance to public health with an emphasis on the endemic infections in Egypt.a2. Demonstrate knowledge and understanding of the biology, pathogenesis, diagnosis, prevention and control of parasitic infections of medical importance.a3. Explain the principals of immunoparasitology and identify parasitic infections commonly occurring in immunocompromised patients.

b- Intellectual skills

By the end of the course the candidate will be able to:

b1. Interpret specific symptoms and signs caused by certain parasitic infections.

b2. Choose the best laboratory investigations to verify the presence of certain parasites and interpret the clinical and laboratory findings to reach a proper diagnosis.b3. Formulate a plan for differential diagnosis with prioritization of the common possibilities for each parasitic infection.

c- Professional skills

By the end of the course the candidate will be able to:

c1- Apply safety measures in the parasitology laboratory.c2- Collect and process different clinical specimens for diagnosis of parasitic infections of medical importancec3- Identify microscopically the parasites with their different stages in urine stool and blood specimens

d- General and transferable skills

By the end of the course the candidate will be able to:

d1- Plan and implement efficient and effective modes of team working.d2- Choose and use appropriate computer program packages, electronic filling management, locate and download online data.d3- Find information independently and visit different internet sites.d4- Find effective solutions for work problems

3- Course content:

20

TOPICS No of hoursL P/C SDL

I. Introduction to parasitology Host-Parasite relationship Clinical manifestations of parasitic diseases Prevalence and transmission of parasitic infections Taxonomy and classification  Anti-parasitic drugs.

2

II. Phylum PlatyhelminthesClass: TrematodaIntroductionFasciola gigantic , F. hepatica , Fasciolopsis buskiHeterophyes heterophyes , Metagonimus yokogawaiSchistosoma haematobium, S. mansoni, S. japonicum Paragonimus westermani

Class: Cestoidea Diphyllobothrium latum, Diphyllobothrium mansoni)Taenia saginata, Taenia solium                                             Echinococcus granulosus, Echinococcus multilocularis                                      Dipylidium caninumHymenolepis nana, Hymenolepis diminuta

3

3

4

III. Phylum: NemathelminthesTrichocephalus trichurisCapillaria hepaticaCapillaria philippinensisTrichinella spiralis Strongyloides stercoralisAncylostoma duodenale , Ancylostoma braziliense , Ancylostoma caninum , Necator americanus Ascaris lumbricoides , Toxocara sp.Enterobius vermicularisWuchereria bancrofti , Wuchereria malayi Onchocerca volvulusLoa loaDracunculus medinensis

3 4

IV. PROTOZOAPhylum  Sarcomastigophora 3 4

21

Class: RhizopodaEntamoeba histolytica Entamoeba coli Acanthamoeba spp .Naegleria fowleri

Class: Zoomastigophorfa (flagellates) Leishmania donovani complexLeishmania tropica complexLeishmania mexicana complexLeishmania braziliensis complexTrypanosoma brucei gambienseTrypanosoma brucei rhodesienseTrypanosoma cruzi Giardia lambliaTrichomonas vaginalis

3

Phylum CiliophoraBalantidium coli

Phylum  Apicomplexa (Sporozoa)Class : SporozoaCryptosporidium parvumEimeria and IsosporaToxoplasma gondii Plasmodium vivax   Plasmodium ovalePlasmodium malariaePlasmodium falciparumBabesia spp.

1

3

V. MEDICAL ENTOMOLOGY

CLASS INSECTAORDER: DIPTERA       [Mosquitoes and Flies]Phlebotomus papatasii (Sandfly)Mosquitoes: Anopheles , Culex , Aedes.Simulium sppCulicoides sp.Glossina sppMusca domestica, Stomoxys calcitransMyiasis causing flies (Calliphora, Sarcophaga, Wohlfartia

3 4

22

spp) and Myiasis

ORDER: SIPHONEPTERA [Fleas]Pulex irritansCtenocephaledes canisCtenocephaledes felisXenopsylla cheopisTunga penetrans

ORDER: ANOPLURA (Lice: biting lice and sucking lice)Pediculus humanus capitis  , Pediculus h. corporis  Phthirus pubis

ORDER: HEMIPTERA       Cimex lectulariusTriatoma megista

CLASS ARACHNIDA (TICKS and MITES) Hard Ticks    Soft TicksSarcoptes scabiei Trombicula akamuchi

CLASS CRUSTACEA (Cyclops)Vector control  Insecticides, rodenticidesHouse dust mitesMyiasis

2

1

1

1

4

VI. Nosocomial Parasitic Infections 1VII. Diagnostic parasitological techniques (for Trematoda, Cestoda, Nematoda and Protozoa) including: Collection, preservation, transport of fecal specimens Macroscopic and microscopic examination of fecal

specimens Examination of blood for parasites Cultivation of parasites Other specimens Parasitic infections of compromised hosts

10

23

L: Lecture P: Practical F: Field training and SDL: Self directed learning

5- Student Assessment Methods

End of Semester exams: Two exams5.1- Biochemistry and Parasitology exams (150 Marks each) distributed as follows:

Written exam. to assess knowledge and intellectual skills: 90 Marks Oral exam to assess knowledge and intellectual skills: 15 marks Practical exam to assess practical skills: 45 Marks

5.2-1st semester Periodic Assessment (100 marks): Two assignments, 50 marks each distributed as follows:

Preparation of different bacterial slides: 50 Marks Writing an essay with presentation: 50 marks

6- List of References6.1- Course Notes (paper and / or electronic)6.2- Essential Books (Text Books)

a) Clinical Parasitology: by Craig, Faust , Beaver (Lippincott Williams & Wilkins, US; 9th edition).

b) Manson's Tropical Diseases: by Cook and Zumla (Saunders Ltd.; 21st edition).

c) Foundations of Parasitology: by Schmidt and Roberts (Times Mirror / Mosby College Publishing).

d) Diagnostic Medical Parasitology: by Garcia (American Society for Microbiology; 5th edition).

e) Markell and Voge's Medical Parasitology: by John , Petri (Saunders; 9th edition).

f) Atlas of Tropical Medicine and Parasitology: by Peters and, Pasvol (Mosby 6th).

g) Immunology and Molecular Biology of Parasitic Infections: by Warren (Blackwell Science Ltd; 3rd Ed edition)

h) Immunity to Parasites: How Parasitic Infections are Controlled: by Wakelin (Cambridge University Press; 2 edition)

6.3- Recommended Books1. Diagnostic Medical Parasitology: by Garcia (American Society

for Microbiology; 5th edition)2. Manson's Tropical Diseases: by Cook and Zumla (Saunders

Ltd.; 21 edition)6.4- Periodicals, Web Sites, etc

24

1. Egyptian Journal of Parasitology2. Parasitologists United Journal3. Egyptian Journal of Basic Sciences4. Egyptian Journal of Immunology5. American Journal of Tropical Medicine and Hygiene6. Transaction of Royal Society of Tropical Medicine and Hygiene7. Journal of Clinical Microbiology8. Journal of Infectious Diseases9. European Journal of Clinical Microbiology10. WHO: www.who.int11. Parasitology Division, Center of Disease Control: www.cdc.dpdx.gov12. Pubmed: www.ncbi.nlm.nih.gov13. Clinical Microbial Review: www.cmr.asm.org14. American Society of Microbiology: www.asm.org15. TDR, a Special Programme for Research and Training in Tropical

Diseases: www.who.int/tdr/16. The World Organisation for Animal Health (OIE): http://www.oie.int/17. The American Society of Parasitologists (ASP):

http://asp.unl.edu/index.php18. Microbiology, Immunology and Parasitology course online “South

Carolina University:www.med.sc.edu:85/book/parasit-sta.htm

25

Fundamentals of Medical Microbiology and Immunology and Basics of Infection Control course specificationsUniversity: Ain Shams Faculty: of Medicine

Course specifications

Programme(s) on which the course is given: Master of Science in Medical

Microbiology and Immunology

Major or minor element of programmes: Major

Department offering the programme: Medical Microbiology and Immunology

Department offering the course: Medical Microbiology and ImmunologyAcademic year / Level: 2nd , semester

Date of specification approval ………………………………………..

A- Basic InformationTitle: Medical Microbiology Code: MI 9003Credit Hours: 6 Lectures: 75 (5 cr)F: - Practical: 30 (1 cr) Total: 105

Co-ordinatorProf. Maha Fathy

B - Professional Information 1 – Overall aims of course: At the end of this course the candidates will:

Acquire a comprehensive knowledge as regards biological characteristics of medically important bacteria, fungi and viruses.

Understand the pathogenic mechanisms involved in infection process and the role of host response in immunopathology.

Acquire a core knowledge and understanding in the subject areas of cellular and molecular components of the immune system.

Identify the basic principles and practices of infection prevention and control.

2- Intended Learning Outcomes (ILOs) from the Course:

a- Knowledge and understanding

26

By the end of the course the candidate will be able to:

a1. Understand basic biology of bacteria, fungi and viruses responsible for human disease including structure, replication and growth.a2. Identify methods of controlling microbial growth in vitroa3. Understand principles of microbial genetics and their applications in the field of medical microbiologya4. Recognize basis of bacterial taxonomy, classification and identificationa5. Explain pathogenic mechanisms involved in establishing of medically important infections a6. Understand epidemiological characteristics of infectious diseasesa7. Identify different classes of antimicrobial drugs, their mechanisms of action and development of resistance a8. Recognize the molecular and cellular mechanisms involved in the

development and regulation of the immune response.a9. Identify risk factors and epidemiological characteristics for health care associated infection transmission a10. Recognize job description for IC positions a11. Identify principles of healthcare personnel safety and healtha12. Recognize principles of rational use of antimicrobialsa13. Describe, the indication, optimal methods for collection, transport, storage, reception, identification and documentation of different clinical and environmental specimens. a14. Explain the principles of different microbiological and immunological laboratory techniques

b. Intellectual SkillsBy the end of the course the candidate will be able to:

b1. Apply principles of microbial cell biology and microbial genetics in clinical and research problemsb2. Differentiate types of host microbe interactionsb3. Correlate different microbial pathogenic mechanisms with disease processb4. Interpret the results of different antimicrobial testsb6. Interpret the results of some serological and antigen based techniquesb7. Interpret results of different laboratory bacterial identification testsb9. Classify different microbes according to risk groupsb10. Appreciate the danger of handling and use of infectious agents on community and environment

27

c. Practical SkillsBy the end of the course the candidate will be able to:

c1. Formulate a policy on the use of sterilization and disinfection in the laboratory, hospital or communityc2. Supervise collection, and safe handling of all routine specimens c3. Process all routine specimens received in the laboratory.c4. Perform current techniques for antimicrobial susceptibility testing with appropriate quality control.c5. Perform and interpret immunological and serological tests.c6. Operate routine and sophisticated instruments in the laboratory.c7. Apply the good laboratory practices and biosafety measures in medical microbiology lab

d- General and transferable skills By the end of the course the candidate will be able to: d1. Communicate effectively through oral presentation, computer processing, written reports and scientific publicationsd2. Acquire management skills: decision processes, objective criteria, problem definition, research design and evaluation, teem-work and coordination.d3. Integrate and evaluate information from a variety of sources.d4. Manage resources and time.d5. Learn independently with open- mindedness and critical enquiry.

28

3- Course content:

Topic No of hoursI. Bacteriology & Mycology: 2 Cr. H L P F SDL1. Prokaryotic cell structureCell wall- Cell membrane-Directed movement of molecules across cytoplasmic membrane (transport & secretion)- Surface layers external to cell wall- Filamentous protein appendages- Internal structures

2

2. Dynamics of prokaryotic growthPrinciples of bacterial growth- Factors influencing bacterial growth (environmental & nutritional)- Bacterial growth in lab. conditions (growth curve- colony growth- continuous culture)- Bacterial growth in nature (bacterial communities interactions- biofilms)

2

3. Control of microbial Growth in vitroPrinciples of control- Using heat, chemicals and radiation to destroy microorganisms- Removal of microorganisms by filtration- Preservation

2

4. Bacterial MetabolismCentral metabolic pathways- Respiration- Fermentation

2

5. Bacterial GeneticsMutation (spontaneous & induced)- Repair of damaged DNA- DNA mediated transformation- Transduction and bacterial viruses- Plasmids and conjugation- Transposable elements- Genetic transfer of virulence factors- Barriers to gene transfer – Recombinant DNA biotechnology

3

6. Identification and Classification of bacteriaPrinciples of taxonomy- Phenotypic characteristics- Genotypic characteristics- Studying strain differences and relatedness

2

7. Host Microbe interactionsAnatomical barrier and normal flora- Principles of infectious diseases- Establishing the cause of infection- Bacterial pathogenesis and establishment of infection-

2

8. Epidemiology of infectious diseasesPrinciples of epidemiology- Epidemiological studies- Infectious disease surveillance- Trends in infection

2

9. Antimicrobial medications 3

29

History and development- Features ( selective toxicity- spectrum of activity- tissue distribution, metabolism and excretion)- Mechanisms of action- Resistance to antimicrobials- Combined antimicrobial therapy- Prophylactic use- Adverse effects and complicationsTotal 20II. Virology: 1 Cr. H L P F SDL1. General properties of viruses , Classification and nomenclature of viruses

2

2. Principles of virus structure 23. Virus Genome Replication 24. Pathogenesis and Control of Viral Diseases 25. Viral Genetics 26. Host Defenses against Viral Infection and Viral Counterdefenses

1

7. Antiviral drugs 28. Viral vaccines 19. Laboratory Diagnosis of Viral Infections 1Total 15III. Immunology : 2 Cr. H L P F SDL1. Overview of the Immune System (Historical Perspective, Innate Immunity, Adaptive Immunity, Comparative Immunity, Immune Dysfunction and Its Consequences).

2

2. Cells and Organs of the Immune System (Hematopoiesis, Cells of the Immune System, Organs of the Immune System (structure &function), lymphocyte Recirculation).

2

3. Innate Immune Response (Mechanical and chemical barriers, Pattern recognition receptors, Phagocytosis, acute phase response, Leukocyte Migration and Inflammation).

2

4. Cell-Adhesion Molecules, Chemokines—Key Mediators of Inflammation.

4

5. Antigens (Immunogenicity Versus Antigenicity, Factors That Influence Immunogenicity, Epitopes, Haptens, Pattern-Recognition Receptors, Heterophil antigens, Adjuvants).

2

6. Antibodies: Structure and Function (Immunoglobulin Fine Structure, Antibody-Mediated

2

30

Effector Functions, Antibody Classes and Biological Activities, Antigenic Determinants on Immunoglobulins, The B-Cell Receptor, The Immunoglobulin Superfamily, Monoclonal Antibodies).

8. Major Histocompatibility Complex(General Organization and Inheritance of the MHC, MHC Molecules and Genes, Detailed Genomic Map of MHC Genes, Cellular Distribution of MHC Molecules, Regulation of MHC Expression, MHC and Immune Responsiveness, MHC and Disease Susceptibility )

2

9. Antigen Processing and Presentation(Antigen-Presenting Cells, Self-MHC Restriction of T Cells, Endogenous Antigens: The Cytosolic Pathway, Exogenous Antigens: The Endocytic Pathway, Presentation of Nonpeptide Antigens).

2

10. T-Cell Receptor(αβ and γϨ T-Cell Receptors: Structure and Roles, Organization and Rearrangement of TCR Genes, T-Cell Receptor Complex: TCR-CD3, T-Cell Accessory Membrane Molecules,Three-Dimensional Structures of TCR-Peptide- MHC Complexes).

2

11. T-Cell Maturation, Activation, and Differentiation(T-Cell Maturation and the Thymus, Thymic Selection of the T-Cell Repertoire, TH-Cell Activation, T-Cell Differentiation, Cell Death and T-Cell Populations, Peripheral γϨ T-Cells. Antigen-Presenting Cells).

2

12. B-Cell Generation, Activation, and Differentiation(B-Cell Maturation, B-Cell Activation and Proliferation, Regulation of the Immune Effector Response).

2

13. The Complement System(The Functions of Complement, The Complement Components, Complement Activation, Regulation of the Complement System, Biological Consequences of Complement Activation, Complement Deficiencies).

2

14. Cytokines 2

31

(Properties of Cytokines, Cytokine Receptors, Cytokine Antagonists, Cytokine Secretion by TH1 and TH2 Subsets, Cytokine-Related Diseases, Therapeutic Uses of Cytokines and Their Receptors, Cytokines in Hematopoiesis).

15. Cell-Mediated Effector Responses(Effector Responses, General Properties of Effector T Cells, Cytotoxic T Cells, Natural Killer Cells, Antibody-Dependent Cell-Mediated Cytotoxicity).

2

Total 30IV. Infection Control: 1Cr.H L P F SDL1. Definitions of health care associated infections (HAIs) 12. Risk factors for nosocomial infection transmission 23. Epidemiological aspects of HAIs 14. Organizational structure for infection prevention and control programThe roles and responsibilities of the infection control team and committee

2

5. Antimicrobial stewardship:Rational use of antimicrobialsClinical use of antibiotics for therapy and prophylaxis.Antibiotic resistance: reservoirs and how to prevent.Antibiotic policy.

2

6. Occupational health and safety 2Total 10

Applied1. Biosafety in microbiological laboratories 2 2. Approaches to diagnostic microbiology

Specimen collection Culture containers and media Culture of bacteria Identification tests Immunological and serological methods Nucleic acid based techniques

12

3. Quantification in microbiology: Methods to detect andmeasure bacterial growth

6

4.Antimicrobial susceptibility tests, lab control of antimicrobial therapy

8

5. Management of experimental animals 2Total 30

32

L: Lecture P: Practical F: Field training and SDL: Self directed learning

4 - Student Assessment Methods (Periodic assessment for 2 nd semester) 4.1. Written examination: MCQ (best of five): 50 Marks. 4.2. Practical examination: 50 Marks.

5 -- List of References5.1- Essential Books (Text Books)

Jawetz, Melnick & Adelberg’s Medical Microbiology Medical Microbiology, Greewood D., Slack R., Peutherer J., and Barer M. Mackie & McCartney Practical Medical Microbiology Basic Immunology, Abul K. Abbas, Andrew H. Lichman. Elsevier

Science (USA). Medical Immunology, Tristram G. Parslow, Daniel P. Sites, Abba I. Terr

and John B. Imboden. McGRAW- Hill Companies, Inc. International Federation of Infection Control: Basic Concepts

(www.theific.org). APIC Text of Infection Control and Epidemiology, Association for

Professionals in Infection Control and Epidemiology, INC.

5.2- Recommended Books Manual of Clinical Microbiology Bailey & Scott’s Diagnostic Microbiology Basic Virology, Edward K. Wagner R. and Atinez J. Fundamental Virology, Bernard N. and david M. Publisher: Lippincott

Williams & Wilkins,. Fields Virology: (Vol.1&2) by Bernard N. Fields (Editor), David M.

Knipe (Editor), Peter M. Howley Immunobiology, The Immune System in Health and Disease, Charles A.

Janeway, Paul Travers, Mark Walport and Marl J. Shlomchik Churchill Livingstone, New York.

Cellular and Molecular Immunology, Abul K. Abbas, Andrew H. Lichman. Elsevier Science (USA).

CDC, Infection Control in Healthcare Settings http://www.cdc.gov/ncidod/dhqp/

WHO, Infection Control Health topics http://www.who.int/topics/infection_control/en/

Information Resources in Infection Control

33

http://www.theific.org/pdf_files/damani_IFIC_resource_5theditiodf Systemic and Applied Medical Microbiology and Immunology and Infection Control course specifications

University: Ain Shams Faculty: of Medicine

Course specifications

Programme(s) on which the course is given: Master of Science in Medical

Microbiology and Immunology

Major or minor element of programmes: Major

Department offering the programme: Medical Microbiology and Immunology

Department offering the course: Medical Microbiology and ImmunologyAcademic year / Level: 3rd and 4th semesters

Date of specification approval ………………………………………..

A- Basic InformationTitle: Medical Microbiology Code: MI 9004Credit Hours: 11 Lectures: 105F: 60 Practical: 90 Total:255Co-ordinatorProf. Maha Fathy

B - Professional Information At the end of this course the candidates will: Acquire a comprehensive knowledge as regards microbiological

characteristics, modes of transmission, pathogenesis and outcomes of common medically important microbial infections.

Recognize modern approaches to the development of therapeutic agents and vaccines for the prevention of human microbial diseases of major significance to public health.

Recognize how the normal function of the immune system eliminates microorganisms, and how its abnormal function leads to human disease.

Gain an in-depth knowledge of cancer and transplantation immunology, autoimmunity, hypersensitivity defects in the immune system, and immunodeficiency.

Acquire knowledge and sufficient practical skills to be a competent specialist in the field of medical microbiology and immunology

34

Be able to participate in education, training and raising awareness regarding infection prevention and control at health care farcicalities and community level.

Be trained in basic research methodology so that they are able to conduct fundamental and applied research.

Be trained in teaching methods so that they can take up teaching assignments

2- Intended Learning Outcomes (ILOs) from the Course:a- Knowledge and understanding By the end of the course the candidate will be able to:

a1. Recognize microbiological, epidemiological and clinical characteristics of medically important microorganisms.a2. Understand concepts and tools of laboratory diagnosis of medically important bacterial, fungal and viral infections.a3-Recognize methods of prevention and treatment of medically important bacterial, fungal and viral infections infection.a4-Discuss viral induced oncogenesis.a5- Explain the different ways by which the immune system responds to different types of microbes and how they can evade the host’s immune response.a6- Identify different types of vaccines, methods of preparation and their application in clinical settings.a7- Understand the ways in which defects in the immune system can lead to hypersensitivity, autoimmunity, tumor and immunodeficiency.a8- Organize the way of manipulation of the immune system for management of the transplantation and cancer.a9. Identify evidence based guidelines for general and standard infection prevention and control measures

b- Intellectual skillsBy the end of the course the candidate will be able to:

b1. Formulate a systematic approach for laboratory diagnosis of medically important microorganismsb2. Correlate the clinical picture with laboratory information to help the physician in establishing the appropriate antimicrobial treatment, prevention and control measures for infectious diseases b3. Perform risk assessment for all procedures undertaken in the laboratory

35

b4- Plan, carry out and evaluate research in the field of medical microbiology and immunology.b5-Evaluate, analyze and interpret laboratory tests related to applied medical microbiological and immunological problems.b6. Perform an infection-control oriented risk assessment for all procedures undertaken in the hospital, including the laboratory and for all categories of workers, including the pregnant and immuno-compromised.b7. Apply clinical and microbiological parameters for identification of HAIs.b8. Experience the practice of audit through evaluating different aseptic processes against the standards according to evidence based IC guidelines.

c- Professional and Practical skillsBy the end of the course the candidate will be able to:

c1. Collect, transport and process pathological specimens for laboratory diagnosis of medically important infectionsc2. Carry out tests necessary for full identification of medically important microorganismsc3. Develop a sense of the continuity of identification of specimens from collection, through culture and further testing to the issuing of a final report. c4. Recommend appropriate typing methods for clinical and epidemiological situations and interpret the results. c5. Provide clinical advice for the selection of the appropriate antimicrobial in the clinical setting based on interpretation of susceptibility testing.c6. Carry out tests for examination of environmental water samplesc7. Advise on appropriate patient placement in different health care settings c8. Initiate and discontinue isolation precautions when indicated.c9. Conduct infection prevention awareness programs for patients and visitors.c10. Participate in educational and training infection prevention and control programs in different health care settings

36

d- General and transferable skills By the end of the course the candidate will be able to: d1. Communicate effectively through oral presentation, computer processing, written reports and scientific publicationsd2. Acquire management skills: decision processes, objective criteria, problem definition, research design and evaluation, teem-work and coordination.d3. Integrate and evaluate information from a variety of sources.d4. Manage resources and time.d5. Learn independently with open- mindedness and critical enquiry.

3. Course Contents

Topic No of hoursI. Systemic and Applied Bacteriology and Mycology (6 credit hours)

L P F SDL

SystemicMorphology & Identification, Antigenic structure, Pathogenesis, Epidemiology, Clinical spectrum, Laboratory diagnosis, Antimicrobial susceptibility. Treatment, Prevention and Control of the following microorganisms:1. Staphylococci & Micrococci 2 42.Streptococci & Enterococci 2 43. Neisseria and Moraxella 2 44.Bacillus 2 25. Listeria, Corynebacterium and other Coryneform bacteria

2 2

6. Erysipelothrix, Lactobacilli, Gardenella & Arcanobacterium

1 2

7. Nocardia, Actinomycetes & Streptomyces 1 8. Enterobacteriaceae :E.coli, Klebsiella, Proteus & other genera SalmonellaShigellaYersinia

3 8

9. Acinetobacter & Stenotrophomonas 110. Pseudomonas, Burkholderia 2 211. Vibrio, Aeromonas, Plesiomonas & Chromobacterium 2 2

37

12. Campylobacter and Helicobacter 2 213. Haemophilus, Bordetella 2 214. Pasteurella, Francisella 215. Brucella 216. Legionella 117. Bartonella, Streptobacillus moniliformis, Spirillum minus, Calymmatobacterium

1

17. Anaerobic bacteria: ClostridiaBacteroidesOther anaerobic bacteria

3

18. Mycobacteria 2 319. Spirochaetes 2 2 20. Mycoplasma, Ureaplasma 2 21. Chlamydia 222. Rickettsia 2 23. Medically important fungi 2 6 624.Approaches to diagnostic microbiology 20

25. Environmental Microbiology (water, milk, air and food)

4

Total 45 45 30II. Systemic and Applied Virology (3.5 credit hours)SystemicStructure, replication, epidemiology, pathogenesis, clinical spectrum, diagnosis and prevention and control of the following viruses:DNA Viruses1. Parvovirus 22. Pox virus 23. Herpes viruses 34. Adenoviruses 25. Papilloma viruses 26. Hepatitis viruses 4RNA Viruses7. Picornaviruses (Enterovirus and Rhinovirus groups) 2 8. Rhinoviruses 2 9. Reoviruses, Rotaviruses and Calciviruses 210. Arthropode-Borne and Rodent- Borne Viral Diseases 211. Orthomyxoviruses (Influenza viruses) 2

38

12. Paramyxoviruses and Rubella Virus 213. Coronaviruses 114. Rabies 215. Slow virus infection and Prion diseases 216. AIDS and Lentiviruses 217. Viruses and Cancer 218. Emerging Viruses 1Applied1.Sampling and Direct Examination of Clinical Materials: Microscopy and staining

2

2. Virus isolation [Tissue culture, Chick embryo, Animal inoculation)

4

3. Direct Antigen Detection , Electron microscopy, immunofluorescence, ELISA, Latex agglutination, PCR

3

4. Serology 35. Nucleic Acid Detection and Hybridization 2Total 38 14III. Systemic and Applied Immunology (2.5 credit hours)Systemic1. Mucosal Immunity 2 2. Immune Response to Infectious Diseases(Viral Infections, Bacterial Infections, Protozoan Diseases, Diseases Caused by Parasitic Worms (Helminths).Fungal diseases).

2

3. Regulation of Immune Response 2 4. Vaccines(Active and Passive Immunization, Designing Vaccines for Active Immunization, Whole-Organism Vaccines, Purified Macromolecules as Vaccines, Recombinant-Vector Vaccines, DNA Vaccines,Multivalent Subunit Vaccines).

2

5. Hypersensitive Reactions(IgE-Mediated (Type I) Hypersensitivity, Antibody-Mediated Cytotoxic (Type II) Hypersensitivity, Immune Complex–Mediated (Type III) Hypersensitivity, Type IV or Delayed-Type Hypersensitivity).

2

6. AIDS and Other Immunodeficiencies(Primary Immunodeficiencies, AIDS and Other Acquired or Secondary Immunodeficiencies).

2

7. Tolerance and Autoimmunity(Organ-Specific Autoimmune Diseases, Systemic

4

39

Autoimmune Diseases, Proposed Mechanisms for Induction of Autoimmunity, Treatment of Autoimmune Diseases). 4. Transplantation Immunology(Immunologic Basis of Graft Rejection, Clinical Manifestations of Graft Rejection, General Immunosuppressive Therapy, Specific Immunosuppressive Therapy, Immune Tolerance to Allografts, Clinical Transplantation).

3

8. Cancer and the Immune System(Malignant Transformation of Cells, Oncogenes and Cancer Induction, Tumors of the Immune System, Tumor Antigens, Immune Response to Tumors, Tumor Evasion of the Immune System, Cancer Immunotherapy).

3

Applied9. Antigen-Antibody Interactions: Principles and Applications(Strength of Antigen-Antibody Interactions, Cross-Reactivity, Precipitation Reactions, Agglutination Reactions, Radioimmunoassay, Enzyme-Linked Immunosorbent Assay, Western Blotting Immunoprecipitation, Immunofluorescence, Flow Cytometry and Fluorescence, Immunoelectron Microscopy).

6

10. HLA Testing (HLA typing, HLA antibody detection, Mixed lymphocytereaction).

3

11. Assessment of immune competence(Phagocytic cell defects complement defects, B cell defects, T cell defects).

4

12. Experimental Systems(Experimental Animal Models, Animal Models for Autoimmune Diseases, Animal models of immune deficiency).

3

Total 22 16IV. Applied Infection Control (1 credit hour)Antisepsis and hand hygiene 2Personal protective equipment 2Patient care equipment management 3 4Environmental cleaning and disinfection 2 4

40

Waste management 2 4Isolation precautions 2 4Aseptic techniques 2 14Total 15 30

41

4 - Student Assessment MethodsFinal Assessment (850 marks)4.1. Written examination to assess knowledge & understanding (500 marks). 4.2. Oral examination to assess knowledge, understanding, intellectual and general transferable skills (80 marks).4.3. Practical examination to assess professional & practical skills (270 marks).

المقررات الدراسية

الثاني للجزءالكود

السا عاتالمعتمدة

عمتحريريلي

شفوي

مجم وعالدرجات

عدداألوراق

الدرجة

اساسياتالميكروبيولوج

الطبية يا والمناعة والمبادئ

العامة لمكافحةالعدوى

MI60036115012030

850 التصنفيات والتطبيقات

فى العمليةعلم

الميكروبيولوحالطبية يا

والمناعة ومكافحةوالعدوى

MI600413135015050

5 -- List of References5.1- Essential Books (Text Books)

Jawetz, Melnick & Adelberg’s Medical Microbiology Medical Microbiology, Greewood D., Slack R., Peutherer J., and Barer M. Mackie & McCartney Practical Medical Microbiology

Basic Immunology, Abul K. Abbas, Andrew H. Lichman. Elsevier Science (USA).

42

Medical Immunology, Tristram G. Parslow, Daniel P. Sites, Abba I. Terr and John B. Imboden. McGRAW- Hill Companies, Inc.

International Federation of Infection Control: Basic Concepts (www.theific.org).

APIC Text of Infection Control and Epidemiology, Association for Professionals in Infection Control and Epidemiology, INC.

5.2- Recommended Books Manual of Clinical Microbiology Bailey & Scott’s Diagnostic Microbiology Basic Virology, Edward K. Wagner R. and Atinez J. Fundamental Virology, Bernard N. and david M. Publisher: Lippincott

Williams & Wilkins,. Fields Virology: (Vol.1&2) by Bernard N. Fields (Editor), David M.

Knipe (Editor), Peter M. Howley Viruses and Human Diseases Authors: James H. Strauss and Ellen G.

Strauss Immunobiology, The Immune System in Health and Disease, Charles A.

Janeway, Paul Travers, Mark Walport and Marl J. Shlomchik Churchill Livingstone, New York.

Cellular and Molecular Immunology, Abul K. Abbas, Andrew H. Lichman. Elsevier Science (USA).

5.3- Periodicals, Web Sites, etc h ttp://www.virology.net/ http://www.ncbi.nlm.nih.gov/ICTVdb/ Medscape:www.medscape.com/infectious diseases Pubmed:www.ncbi.nlm.nih.gov/pubmed http://www.nature.com/ http://www.sciencedirect.com/ Allergy/Asthma Information Association - http://www.aaia.ca Canadian Society Of Allergy and Clinical Immunology -

http://www.csaci.ca http://www.paediatric-infectious-diseases.com/immunology.htm Link to immunological societies

http://www.proimmune.com/ecommerce/page.php?page=Immunology-Societies

43

http://www.biology.arizona.edu/immunology/microbiology_immunology.html

IDN-SysAdmin@slackinc.com CDC, Infection Control in Healthcare Settings

http://www.cdc.gov/ncidod/dhqp/ WHO, Infection Control Health topics

http://www.who.int/topics/infection_control/en/ Information Resources in Infection Control

http://www.theific.org/pdf_files/damani_IFIC_resource_5thedition.pdf American Journal of Infection Control:

http://www.ajicjournal.org/ Infection Control And Hospital Epidemiology

http://www.shea-online.org/publications/iche.cfm

44

Elective courses:

1- Medical and Research Ethics Course:

University: Ain Shams University Faculty: of Medicine

Course specificationsProgram on which the course is given: Master of Science Degree in Medical Microbiology and ImmunologyMajor or minor element of programs: Minor

Department offering the program: Medical Microbiology and Immunology Department

Department offering the course: Medical Microbiology and Immunology Department

Academic Level: Master of Science – 2nd, 3rd or 4th semester

Date of specification approval: …………………………..

A- Basic Information

Title: Medical and Research Ethics CourseCode: E9034Credit Hours: 1 hour Lecture: 1h/week Total: 15 Coordinator: Medical Microbiology and Immunology Department

B - Professional Information

1- Course Aim:

To boost doctors morals, motivation and retention, and create a positive and productive professional attitude.

2- Intended Learning Outcomes (ILOs) from the Course:By the end of the course, graduates are expected to be able to:

45

1. Recall the meaning of key words included in medical and research ethics principles.2. Recognize what is meant by professionalism3. Identify ethical dilemma similar to those encountered in routine medical and research practice4. Recognize the social and moral dimensions of ethical dilemmas in healthcare5. Describe the framework of solving ethical dilemmas in medical and research practice6. Solve some common ethical dilemmas based on the framework and personnel experience

Main topics

1. Introduction to medical and research ethical principles2. Ethical theories and how they apply to medical and research practice3. Ethical reasoning4. Belmont report and the code of medical ethics5. Framework for recognition and solving ethical dilemmas6. Real ethical scenarios

The teaching methods

The following teaching and learning methods will be used Lectures, demonstrations and Interactive discussions/brain storming

sessions Hands-on training on solving simulated ethical problems Readings and a list of useful websites

The assessment methods

Written exam: 40 Oral exam: 10

46

2- Medical statistics course specificationUniversity: Ain Shams University Faculty: of Medicine

Course specificationsProgram on which the course is given: Master of Science Degree in Medical Microbiology and Immunology

Major or minor element of programs: Minor

Department offering the program: Medical Microbiology and Immunology Department

Department offering the course: Community, Environmental and Occupational Medicine

Academic Level: Master of Science – 2nd, 3rd or 4th semester

Date of specification approval: …………………………..

A- Basic Information

Title: Medical statistics courseCode: E9009Credit Hours: 1 hour Coordinator: Community, Environmental and Occupational Medicine Department

B - Professional Information

1- Course Aim:

To enable the candidate to plan, conduct, analyze and interpret the results of a research in his specific field. This course unit introduces the application of statistical ideas and methodology to medical research.

2- Intended Learning Outcomes (ILOs) from the Course:

a- Knowledge and understandingBy the end of the course the candidate will be able to:

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a1 - Define medical statistics and identify uses and importance of medical statistics in medical researcha2 – Define:

Types of variables. Descriptive statistics. Presentation and summarization of data. Measures of central tendency and scatter. Principles of probability and probability distributions. Concepts of inferential statistics: confidence interval and hypothesis

testing. Different tests of statistical significance. Difference between parametric and nonparametric tests of significance. Correlation and regression Concept of statistical modeling using multivariable and multivariate

statistical methods. Combining evidence from different studies and meta-analysis Importance and methods of sampling and how to determinate the suitable

sample size. Different types of research methodology:

observational and intervention studies and the different statistical issues related to the design, conduct, analysis and interpretation of the results of each study type.

Ethical aspects of medical research including those specifically applied to clinical trials.

b- Intellectual skillsBy the end of the course the candidate will be able to:

b1 - Interpret correctly the results of statistical analyses and critically evaluate the use of statistics in the medical literature.b2 - Integrate and evaluate information from a variety of sources.

c- Professional skillsBy the end of the course the candidate will be able to:

c1- Select appropriate study designs to address questions of medical relevancec2 - Select and apply appropriate statistical methods for analyzing data typically encountered in medical applications.c3- Use selected software packages for statistical analysis and data management.

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d- General and transferable skills By the end of the course the candidate will be able to:

d1 - Work effectively in a group from different backgrounds. d2 - Respects the role of staff and co-staff members regardless of degree or occupation.d3 - Communicate effectively with professional statisticians and the wider medical community, including the ability to present results of statistical analyses through written and oral presentationsd4 - Use of computer data bases and other computer skills.d5 - Handle data appropriately and analyze them through: decision processes, objective criteria, problem definition, project design and evaluation, risk management, teamwork and coordination. d6 - Learn independently with open-mindedness and critical enquiry.3- Course content:

Topics HoursT C/P

1. Introduction to medical statistics and its usesTypes of variables and Descriptive statistics Graphic presentation of data

1

2. Introduction to probability theory and rules 13. Sample and population: sampling distribution of mean and

proportion1

4. Confidence interval of a mean and a proportionConfidence interval of a difference between two mean /proportion

1

5. Testing a hypothesis about population mean/proportion 16. Testing a hypothesis about the difference between two

means/proportion1

7. Comparing between more than two means-Introduction to factorial analysis

1

8. Cross-tabulation and introduction to categorical data analysis

1

9. Simple correlation and simple regression 110. Introduction to multivariable and multivariate analysis 111. Study designs: observational studies

Study designs: Intervention studies: clinical trials2

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Study designs: Experimental animal studiesStudy designs: Bias and Confounding

12. Ethical issues in medical research 113. Sample size estimation for continuous and binary outcome

measures. 1

14. Meta-analysis and publication bias. 1

T: Tutorial and C/P: Clinical or Practical and SDL: Self directed learning

4 - Student Assessment Methods

4-1 Written exam to assess knowledge and understanding and will concentrate on problem solving questions

4-2 Weighing of assessmentWritten exam 40Oral exam 10

Total 50

5 - List of References

5.1- Course Notes (paper and / or electronic)Student Notes on Medical Statistics and Research Methods. Prof. Mohsen Abdel Hamid and Dr Moustafa El Houssinie. Department of Community, Environmental and Occupational Medicine.

5.2- Essential Books (Text Books)Statistics in Clinical Practice. avid Coggon. BMJ Books. 2nd edition 2003

5.3- Recommended BooksHandbook of Epidemiology. Springer 2005

5.4- Periodicals, Web Sites, etc www.brettscaife.net/statistics/introstat/ onlinestatbook.com/rvls/ www. Epidemiolog.net http://www.shef.ac.uk/scharr/spss/

50

ModulesV- GENERAL INFORMATION

1 - MONITORING OF TRAINING AND SUBMISSION OF TRAINING REPORTS

You must keep proper and updated records in your logbook to reflect the activities encountered in your training. Your logbook must be duly endorsed by an authorized signatory at the end of each semester.

You will be continuously assessed by your supervisors, in consultation with head of department. An assessment will be submitted within 2 weeks of completion of each semester.

2 - MISCELLANEOUS INFORMATION:

INJURY AND/OR BLOOD OR BODY FLUID EXPOSURE: During regular working hours, you should immediately report an exposure incident to --------------------------. If exposure occurs after regular working hours or during a weekend or holiday; please call the ----------------------------------------. For injury, please report to the Emergency Department. Please also be sure to inform the supervisors of an exposure incident and/or injury.

3 - ACTION ON COMPLETION OF CLINICAL TRAININGOnce all training sessions are completed the log book should be signed by

the senior supervisor and the head of the department and then should be submitted to post graduate Secretariat.

4- REFERENCEThe Training Guide is available at the post graduate Secretariat and could be downloaded from the following website is

---------------------------------------------------------------

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VI – YOUR LOG BOOK

1- IntroductionThe aim of this book is to give you a guide to the expectations for each

item. It will be a guide for both you and your teachers to what you should be seeing and doing.

It will give you a list of the important topics that you should think about and should be covered in:

1. Clinical or practical sessions or2. Tutorialsor3. Self-directed learning (SDL)

For each item there is also a list of1. Clinical conditions or Practical sessions to be seen or

attended (According to each degree)2. Practical procedures to be seen and done

Remember

This document is only a guide. It is not an exhaustive list. It is not just a checklist to score points. It is a guide to encourage you to read and learn more. This book is for your benefit. It will form a record of your clinical training and experience.

2 - Supervisors

………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………………

3–Tables for Training RecordsCandidates are required to fulfill 75% of the listed activities in order to be eligible for the exam entry. The minimum number required for each activity = 75%. You are free to attend more and record your extra attendance.

52

Medical Microbiology, Immunology and Infection ControlConferences attendance

(NB. Minimum number required is 6)

No

Dat

e

Plac

eTopics Supervisor

signature

Department Weekly Seminars Attendance(NB. Minimum number required is 20)

No Date Place Topics Supervisor signature

53

Department Weekly Seminars Presentation(NB. Minimum number required is 3)

No Date Place Topics Supervisor signature

Thesis attendance(NB. Minimum number required is10)

No Date Place Name of the thesis Supervisor signature

Web CME certificates in the field of Medical Microbiology, Immunology and Infection Prevention and Control

(NB. Minimum number required is 10)

No Name of CME module Web site Supervisor signature

12345678910

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Practical SkillsI. Good Laboratory Practice Training

Skill Date Supervisor Sign.

1. Preplanning and preparation of equipment and material before start of work

2. Wearing and taking off personal protective equipment appropriately

3. Hand washing

4. Use of aseptic techniques when handling specimens and cultures

5. Safe Pipetting technique

6. Safe centrifugation

7. Safe handling of hypodermic needles and othe rsharps

8.Decontaminating working surfaces at the end of work

9. Emergency response to spillage

10. Decontamination of specimens and safe disposal of other laboratory waste

55

II. Medical Microbiology Laboratory Skills

1. Microscopy

Skill Date I confirm that experience has been

acquired

Supervisor Sign.

1. L/M microscope “Examination of different Stained preparations". 2. Fluorescent microscope

3. Dark field microscope “Demonstration”4. Electron Microscope“Demonstration”

2. Preparation and Fixation of Smears

Skill Date I confirm that experience has been

acquired

Supervisor Sign.1. Labeling of slides

2. How to make smears: from

Cultures

Swabs

Sputum

Urine

CSF

Fecal specimen

3. Fixation of smears

56

3. Staining

Skill Date I confirm that experience has been

acquired

Supervisor Sign.Preparation of stained smears: Simple stain- Methylene blue Differential stain

- Gram stain (+ve & -ve)- Acid Fast stain for T.B

Z.N. stain “hot method” Kinyoun method “cold method”

4. Culture Media and Preservation of Stock Cultures

Skill Date I confirm that experience has been acquired

Supervisor Sign.

1. Preparation of different culture media-Nutrient agar - Blood agar-MacConkey’s agar

- Chocolate agar

- Loeffler’s serum

- Lowenstein Jensen

- Blood tellurite - Robertson cooked meat broth

- Bile esculin - Mannitol salt agar

- TCBS - DCA - CLED

3. Preservation of stock culture

57

- Soft agar-Long preservation-Lyopholization

4. Preparation of media for biochemical reactions

58

5. Inoculation of Culture Media

Skill Date I confirm that experience has been

acquired

Supervisor Sign.

1. Aseptic techniques

2. Inoculation of specimens on culture plates

3. Inoculation of slopes

4. Inoculation of deep agar medium

5. Inoculation of fluid media

6. Labeling of inoculated media

7. Incubation of inoculated media: temperature, humidity, different gaseous atmosphere.

8. Anaerobic culturing :

- Anaerobic jar & Gas Pack System

59

6. Tests for Bacterial Identification

Skill Date I confirm that experience has been

acquired

Supervisor Sign.

1. Catalase test

2. Coagulase test

3. Bile solubility test

4. Citrate utilization

5. DNase test

6. Indole test

7. Litmus milk test

8. Oxidase test

9. Urease test

10. Sugar fermentation tests

11. MIO, LIA, TSI tests

12. Bacterial identification by API system

7. Collection of Specimen for Bacteriological Examination

Skill Date I confirm that experience has been

acquired

Supervisor Sign.

1. Pus :

Swabs

Syringe

2. Upper respiratory tract specimens:

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Conjunctival swab

Throat swab

Nasopharyngeal swab

Anterior naris swab

Nasal wash

3. Lower respiratory tract specimens

Sputum

Induced sputum

Endotracheal-aspirate(ETA)

BAL

PSB2. Urine specimen : MSU From catheterized patients Infants samples

3. Female genital samples

High vaginal swab,

Endo cervical swab

4. CSF by lumbar puncture

5. Blood for blood culture

6- Fecal specimens

Stool and diarrheal fluid

Rectal swabs

7- Environmental samples.

Surface samples

Swabing methods

Rinsing method

61

Fluid samples: water and dialysate fluid samples from hemodialysis units

62

8. Examination of LRT specimens Skill Date I confirm that

experience has been acquired

Supervisor Sign.1 specimen Macroscopic appearance2. Preparation of specimen

- Liquefaction-Liquefaction & Decontamination

3. Microscopical examination- Testing reliability of the specimen

- Gram smear - Z.N. stain - Cold stain for AFB4. Culture and quantitative culture

- Blood agar- Chocolate agar- Media for isolation of t.b. 5. Identification and reporting.

9. Examination of Fecal SpecimensSkill Date I confirm that

experience has been acquired

Supervisor Sign.1. Specimen (macroscopic appearance)2. Enrichement and Culture

- MacConkey’s agar- DCA, S & S- Hectoen agar media - TCBS3. Identification, Confirmation (slide agglutination tests) and reporting.

10. Examination of Urine: Skill Date I confirm that

experience has been

63

acquiredSupervisor Sign.

1. Specimen Macroscopic appearanceDip stick test

2. Microscopical examination- Gram-stain- Wet preparation

3.Quantitative Culture Semi quantitative: Dip Slide

4. Identification & reporting11. Examination of Pus:

Skill Date I confirm that experience has been

acquiredSupervisor Sign.

1. Microscopical examination2. Culture (Blood Agar & Mac Conkey's agar media)(aerobic & anaerobic)3. Culture Identification & reporting.

12. Blood CultureSkill Date I confirm that

experience has been acquired

Supervisor Sign.1. Inoculation of blood culture bottle2. Examine microscopically

3. Subculture on:- Blood & Chocolate agar- MacConkey’s agar4. Culture examination and reporting significant growth

64

13. Antimicrobial susceptibility testingSkill Date I confirm that

experience has been acquired

Supervisor Sign.Disc Diffusion Min. inhibitory conc.(MIC)Min. bactericidal conc.(MBC)E-TestDetection of:

- MRSA- VRSA- VRE- ESBL- Other B lactamses prod

65

14. Examination of WaterSkill Date I confirm that

experience has been acquired

Supervisor Sign.1. Collection of water samples from different sources

2. Bacteriological testing of water

Membrane filtration techniqueInoculation of culture bottle, tubes (Most probable number) (Coliforms, Enterococci, Pseudomonas, Staphylococci)Colony count ( pour plate method)3. Subculture on:- MacConkey’s agar-Eijkman's test-Bile Esculin hydrolysis test4. Examination and reporting

15. Sterilization and Disinfection:Skill Date I confirm that

experience has been acquired

Supervisor Sign.1. Use of autoclave2. Test of autoclave efficiency

- Chemical- Biological

3. Use of hot air oven4. Sterilization by Sietz filter and other filters

66

III. Medical Virology Laboratory SkillsMicropipettes

Skill Date I confirm that experience has been

acquiredSupervisor Sign.

1. Different types and applications2. How to use it

Inverted Microscope Skill Date I confirm that

experience has been acquired

Supervisor Sign.1. Uses2. Interpretation of results

Isolation of the Virus from Clinical Specimens:Skill Date I confirm that

experience has been acquired

Supervisor Sign.1. Preparation of specimens before inoculation2. Required equipments and reagents

Serological Tests for the Diagnosis of Viral InfectionDetection of Specific Viral Antigens and/or Antibodies by:

Skill Date I confirm that experience has been

acquiredSupervisor Sign.

1. IFT2. NT3. HIT

67

Detection of Viral Nucleic Acid in Clinical Specimens: Skill Date I confirm that

experience has been acquired

I confirm that experience has been

acquiredSupervisor Sign.

1. Nucleic acid hybridization2. Polymerase chain reaction (PCR)

IV. Medical Immunology Laboratory Skills Agglutination tests (slide & tube):Widal testBrucella testing Test Procedures Date I confirm that

experience has been acquired

Supervisor Sign.1. Separation of patient serum2. Serial dilution of patient serum (micropipette) 3. Addition of patient serum to antigen4. Preparation of controls5. Proper conditions for reactants6. Interpretation of results

68

Antistreptolysin O titrationTest Procedures Date I confirm that

experience has been acquired

Supervisor Sign.1. Separation of patient serum2. Serial dilution of patient serum (micropipette)

3. Addition of patient serum to RBCS4. Addition of streptolysin O5. Preparation of controls6. Proper conditions for reactants7. Interpretation of the results

ELISATest Procedures Date I confirm that

experience has been acquired

Supervisor Sign1. Separation of patient serum2. Serial dilution of patient serum (micropipette) 3. Addition of patient serum to wells of microtitre plates4. Washing step5. Addition of substrate6. Addition of human anti γ globulin7. Preparation of controls8. Proper conditions for reactants9. Interpretation of the results

69

Tuberculin testTest Procedures Date I confirm that

experience has been acquired

Supervisor Sign.1. I.D. injection of PPD2. Measure induration reaction3. Interpretation of the results

70

V. Basic Infection Control Practices Training

Subject Place Date Supervisor sig.Hand Hygiene Hand Washing Antiseptic Hand Washing Hand Rub Surgical Hand antisepsisPersonal Protective Equipment

Putting on for clean technique

Putting on for sterile technique

Taking offAseptic Techniques

Clean Sterile

Patient care equipment management

Cleaning Disinfection: low,

intermediate and high level Sterilization by autoclaves Sterilization by hot air ovens Sterilization of heat sensitive

items: EO, H2O2 gas plasma, chemical

Environmental protection Surface barrier protection Cleaning and disinfection Dealing with blood/OPIF

spillsWaste managementIsolation Precautions

71

Field Laboratory Training Minimum required: 10 specimens

Serial

Type of pathological specimen

Date Supervisor sig.

1.2.3.4.5.6.7.8.9.10.

72

Field IC Training Minimum required: 10 activities

(Observation and auditing different processes related to aseptic techniques)

Nameof hospital/training

centre

Date Activitiy/s Trainer sig.

Supervisor sig.

1.2.3.4.5.6.7.8.9.10.

73

5 - Log book previewThe candidate logbook will be reviewed and patients seen/ skills

performed summarized by diagnosis groups during the semester evaluation and at the end of the course in the table below. The results of this review will be totaled in the summary chart below.

Summary

Skills acquired 1st semester

2nd

semester3rd

semester4th

semester

Microbiological Laboratory skills

Check yes if acquired

Check yes if

acquired

Check yes if

acquired

Check yes if

acquired1. Good Laboratory practices2. Microscopy

3. Preparation and Fixation of Smears4. Staining5. Preparation and Fixation of Smears6. Preparation of Culture Media and Preservation of Stock Cultures

7. Tests for Bacterial Identification8. Collection of Specimen for Bacteriological ExaminationSpecimen examination9. LRT specimens10. Fecal Specimens11. Urine specimens12. Pus13. Blood culturesAntimicrobial susceptibility testing14. Disc diffusion15. MIC

74

16. Detection of MRSA17. Detection of ESβLs18. Water examination19. Laboratory sterilization and disinfectionVirology laboratory skills20. Use of Micropipettes21. Inverted Microscopy22. Isolation of the Virus from Clinical Specimens23. Serological Tests for the Diagnosis of Viral Infection24. Detection of Viral Nucleic Acid in Clinical SpecimensImmunology laboratory skills25. Slide agglutination tests26. Tube agglutination tests27. Antistreptolysin “O” titration test28. EIAs29. Tuberculin TestBasic infection control practices30. Hand Hygiene31. Personal Protective Equipment32. Aseptic Techniques33. Patient care equipment management34. Environmental protection35. Waste management36. Isolation Precautions

Total (36)

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Semester 1st 2nd 3rd 4th TotalActivities No No No NoMedical Microbiology, Immunology and Infection ControlConferences attendance (6)Department Weekly Seminars attendance (20)Department Weekly Seminars preparation and presentation (6)Thesis attendance (10)Web CME certificates (10)Field Laboratory training (10 specimens)Field IC training (10 activities)

VII - HEAD OF DEPARTMENT APPROVAL FOR THE EXAM ENTRY________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________

76

77

VIII – THESIS FOLLOW UP

لعام / السنوى النصف التقريرالطالب / عن

الدكتوراة ( / ) ماجسيتر لدرجة القيدبقسم /

المشرفون االساتذة السادة تقريربدأ العلمية المادة محدودا جمع شوطا قطع

اإلنتهاء على أوشك المقدمة كتابة الجمع و من إنتهى

بدأ العملى محددا الجزء شوطا قطعاإلنتهاء على التحليل أوشك من إنتهى

بدأ النتائج محدودا مناقشة شوطا قطع

اإلنتهاء على التحرير أوشك من إنتهى

بدأ المشرف مع النهائية محددا المراجعة شوطا قطع

اإلنتهاء على تماما أوشك إنتهت

------------------------------------------------------------------------------------------------

المشرفون السادة رأىالطالب قيد القيد إستمرار مدالطالب قيد شطب

78

التشكيل / تاريخ نعم المناقشة لجنة تشكيل تم /

ال القيد / شطب مد

VIII – EVALUATION FORMS

To be completed at -------------------------------------Candidate SupervisorLocation

Aim of training ______________________________________________________________________________________________________________________________________________________________________________________________________ Agreed educational objectives and timescale in which objectives should be achieved. ______________________________________________________________________________________________________________________________________________________________________________________________________

Comments by Candidate______________________________________________________________________________________________________________________________________________________________________________________________________

Comments by Supervisor ________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________

Date of next meeting

Signed by candidate

Signed by Supervisor

Date

79

Degree Program Evaluation Form By The CandidatePlease consider each pair of statements and decide which most clearly reflects your view and tick one box or answer the question.

I. Individual Information1. Are you a graduate of ASU?

yes no to some degree2. Year and semester when studies began:

II. General Questions1. What are the advantages/disadvantages of the general study environment at the University ASU?

2. What were your expectations when you applied to the degree?

3. Do you feel that the degree program prepares you well for your future studies or employment according to the demands and expectations of those institutions?

yes no to some degree

4. Has the time limit of the program (two or three academic years) caused you any difficulties or inconveniences?

yes no to some degree

III. Structure of Degree Program1. Did you receive enough guidance in planning your study schedule in the beginning of the program?

yes no to some degree

2. What were the main difficulties in the planning of your study schedule?

3. What is your general opinion on the structure of the degree program?

80

4. In your opinion, does the degree program offer a good balance of lectures, seminars, conferences, and book exams?

yes no to some degree

a) General Studies

i) Do you feel that you have received enough guidance on academic writing?

yes no to some degree

ii) Do you feel that you have acquired sufficient knowledge on research skills (eg. quantitative and qualitative research methods)?

yes no to some degree

b) Courses

i) Have you had some special difficulties in completing some of the courses? Please specify.

ii) Has there been a sufficient variety of courses offered for your optional studies?

yes no to some degree

iii) Have you received enough guidance for the preparation of your thesis?

yes no to some degree

IV. Concluding Points1. Did the degree program meet your expectations?

yes no to some degree2. What aspects of the degree program do you particularly like?

3. What aspects of the degree program do you particularly dislike?

4. What are your suggestions on how to improve the program?

Thank you!

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