md in clinical and chemical pathology - bu...اـهنب ةـعماج بطا ةي 2 in the...

اـة بنهـجامع كمية الطب

1

MD in Clinical and Chemical Pathology توصيف برنامج

:معلومات أساسية

MD in Clinical and Chemical Pathology ـ اسم البرنامج : 1

( أحادىـ طبيعة البرنامج : ) 2

Clinical and Chemical Pathology department نامج :عن البر ةالمسئول األقسام

11/2212/ 7 :فى مجلس القسم رار البرنامجتاريخ إق

11/2212 /21 تاريخ إقرار البرنامج فى مجلس الكلية:

:معلومات متخصصة

: ـ األهداف العامة للبرنامج 1

1-Overall Aims of the Program:

The overall goals of the program are to develop a clinical pathologist

(CP) with the following characteristics:

1.a. Capable of communicating as a medical consultant to other clinicians

and to patients, as well as being capable of optimally directing the

management of the clinical laboratory enterprise.

1. b. Knowing the science and technology of the clinical laboratory and

assures the quality, clinical appropriateness, and usefulness of the data

produced by that laboratory. The CP is a clinician first and foremost.

1.c. Consulting on methods of diagnostic test development, test utilization in

the context of both generally applicable as well as patient- specific

clinical settings, and assay interpretation in the acute and chronic

clinical management of patients. These activities include the CP's role


2

in the development and implementation of integrated medical

informatics that optimizes patients care.

1.d. Acquiring the skills to consult in these areas at the broader systems

level, and in the various healthcare delivery models.

1.e. Outline the role of research, in its broadest definition and capable of

continuing education.

1.f. Identifying the appropriate laboratory methods in diagnosis of diseases.

1.g. Mastering the performance of laboratory skills for diagnosis of diseases.

: ـ المخرجات التعليمية المستهدفة من البرنامج 2

arning Outcomes (ILOS):Intended Le-2

:المعرفة والفهم ـ أ

2.a. Knowledge and Understanding

By the end of the program the graduate should be able to:

2.a.1. State the basic principles and practice of Clinical Chemistry or

Clinical Hematology or Clinical Microbiology or Clinical

Immunology.

2.a.2. Outline the principles of laboratory safety and regulations

(laboratory hazards and protective equipments).

2.a.3. Define the basis of statistics, quality control and assurance

(definition of terms, calculations, preanalytic and postanalytic

phases of quality assurance).

2.a.4. Describe the analytical techniques, instrumentation and

automation.

2.a.5. Explain the immunoassays and nucleic acid probe techniques.

2.a.6. List the molecular diagnostic techniques.


3

2.a.7. Know the effect of professional practice on the surrounding

environment.

:القدراث الذهنيت ب ـ

2.b. General Intellectual Skills:-

By the end of the program the graduate should be able to:

2.b.1. Integrate the results of history, physical and laboratory test findings

into a meaningful diagnostic formulation (problem solving skills).

2.b.2. Demonstrate their ability to think critically by recognizing the

impact of their own value judgments and those of patients.

2.b.3. Define priories and manage problems.

2.b.4. Analyze, interpret, objectively evaluate and priories information,

recognizing its limitations.

2.b.5. Demonstrate insights into research and scientific methods through:

a. Understanding and clinical appreciation of methodology.

b. Formulating research questions that are relevant to medicine.

c. Choosing and application of appropriate quantitative and qualitative

methodologies.

d. Recognition of the importance of collecting analyzing and

interpreting data.

e. Recognition of the relationship between evidence, audit and observed

variation in clinical practice.

2.b.6. Exhibit creativity/ resourcefulness' in their professional learning,

scientific endeavour and clinical practice.

2.b.7. Recognize and cope with uncertainty by:

a. Accepting that uncertainty is unavoidable in the practice of medicine.


4

b. Using appropriate intellectual strategy to deal with uncertainty when

it arises.

:المهارات ج ـ

2.c. Skills:-

: . مهارات مهنية وعمليةأ ج

2.c.a. Practical Skills:-

By the end of the program the graduate according to his specialty should

be able to:

2.c.a.1. Convert results from one unit format to another using the SI system.

2.c.a.2. Determine the missing variable ,when either the pK and pH or the

pK and concentration of the weak acid and its conjugate base are given

using the Hendrson – Hasselbalch equation.

2.c.a.3. Analyze the data given in a CBC or Bone Marrow report.

2.c.a.4. Define different types of anticoagulants and their optimal

concentrations.

2.c.a.5. List different types of microbiological cultures.

2.c.a.6. State different types of immunological techniques.

2.c.a.7. List the types and discuss the proper use of a centrifuge, analytical

balance, and glassware for diluting concentrated substances.

2.c.a.8. Differentiate the type of pipette when an actual pipette or its

description is given.

2.c.a.9. Apply two ways to calibrate a pipetting device.

2.c.a.10. List the proper drawing order for collection tubes.

2.c.a.11. Identify the additive preservative if present when give a collection

stopper color.


5

. مهارات عامة :ب ج

2.c.b. General and transferable skills:-

By the end of the program the graduate will be able to: 2.c.b.1. Communicate effectively with teaching staff, colleagues and the

community.

2.c.b.2. Demonstrate appropriate attitude towards teaching staff, colleagues

and patients.

2.c.b.3. Use information technology.

2.c.b.4. Do good control of timing.

2.c.b.5. Perform continuous self teaching.

2.c.b.6. Present information clearly in written, electronic and oral form.

2.c.b.7. Communicate ideas and arguments effectively.

2.c.b.8. Apply the principles of scientific research.

2.c.b.9. Deal with uncertainty and work within a changing environment.

2.c.b.10. Teach effectively and act as a monitor to others.

2.c.b.11. Communicate effectively with individuals regardless of their social,

cultural or ethnic background or their disabilities.


6

:ـ المعايير األكاديمية 3

3. Academic Standards:

By the end of the program the graduate will be able to:

3.1. Describe and interpret the laboratory investigations according to his

specialty (Clinical Chemistry, Clinical Hematology, Clinical

Microbiology or Clinical Immunology).

3.2. Select appropriate investigations for diagnosis, assessment of prognosis

and monitoring of different diseases.

3.3. Understand and interpret different laboratory reports in different patients

in health and disease, both in diagnosis and in following up treatment.

3.4. Understand the limitations of diagnostic investigations.

3.5. Understand the transfusion process and ensure the safe and effective use

of blood and blood products.

3.6. Lay the basis for life-long learning of integrated clinic-pathological

features of diseases.

3.7. Develop an evidence-based approach to the study of clinical pathology.

: العالمات المرجعيةـ 4

4. External references for standards (Benchmarks):

4.1. General academic standards for postgraduate programs.

4.2. Academic standards of university of Cambridge (School of clinical

medicine – Addenbrook's hospital).


7

القياسية: عايير المرجعيةالممع امج من نتائج تعليمية مستهدفةيقدمه البرنمقارنة ما ـ 5

:المعرفة والفهم ـ أ

المقزراث التى تحقق المعاييز

امج نلبزلاألكاديميت

للبزنامج المتبناة المعاييز األكاديميت

ألكاديميت والتى تتىافق مع المعاييز ا

القياسيت

(ARS)

Benchmark

لجامعت المعاييز األكاديميت

كامبزيدج

(NARS)

األكاديميت المعاييز القىميت

لبزامج العامت القياسيت

قطاع الدراساث العليا )درجت

الدكتىراه(

Clinical Hematology

Clinical Immunology

Clinical Microbiology

Clinical Chemistry

By the end of the program the

graduate should be able to:

1. State the basic principles

and practice of Clinical

Chemistry or Clinical

Hematology or Clinical

Microbiology or Clinical

Immunology.

By the end of the

program the graduate

should be able to:

1. Understand etiology

and pathogenesis of

clinically important

disease processes.

By the end of the


should be able to:

1. Know the basic

principles and practice

and recent advances in

each specialty.

2. Outline the principles of

laboratory safety and

regulations (laboratory hazards

and protective equipments).

2. Understand the

pathological processes

that lead to

hematological,

chemical and

immunological

changes.

2. Know the basic

principles and practice

of scientific research.

3. Define the basis of statistics,

quality control and assurance

(definition of terms,

calculations, preanalytic and

postanalytic phases of quality

assurance).

3. Understand the

results of pathological

investigations in

different patients and

understand the

limitations of

diagnostic

investigations.

3. Know the legal and

moral principles in

professional practice.

4. Describe the analytical

techniques, instrumentation

and automation.

4. Understand the

transmission of

microorganisms

between the

environment and

living hosts, and how

this transmission may

be reduced or

prevented and how

4. Know the basic

principles of quality

control in professional

practice in each

specialty.


8

host defense

mechanisms may be

altered.

5. Explain the immunoassays

and nucleic acid probe

techniques.

5. Understand the

principles of how best

to use microbiological

tests to make a

diagnosis of infectious

diseases in patients in

and out of hospital.

6. List the molecular

diagnostic techniques.

6. Understand the

principles of how best

to use chemical

pathology tests to

make a diagnosis of

various diseases in

patients in and out of

hospital.

7. Know the effect of

professional practice on the

surrounding environment.

7. Understand the

clinical presentation of

hematological

disorders and the

hematological aspects

of systemic diseases.

:القدرات الذهنية ب ـ


امج نزبللاألكاديميت

المتبناة المعاييز األكاديميت

للبزنامج والتى تتىافق مع المعاييز

ألكاديميت القياسيت ا

(ARS)

Benchmark


كامبزيدج

(NARS)

المعاييز القىميت األكاديميت

لبزامج قطاع ت العامالقياسيت

الدراساث العليا )درجت

الدكتىراه(

Clinical Hematology

Clinical Immunology


By the end of the program

the graduate should be

able to:

1. Integrate the results of

history, physical and

laboratory test findings

into a meaningful

diagnostic formulation

(problem solving skills).

By the end of the


should be able to:

1. Select appropriate

pathological

investigations for

diagnosis, assessment

of prognosis and

monitoring of common

By the end of the


should be able to:

1. Analyze, evaluate

and interpret data

according to each

specialty.


9

Clinical Chemistry

diseases.

2. Demonstrate their

ability to think critically

by recognizing the impact

of their own value

judgments and those of

patients.

2. Interpret the results

of pathological

investigations in

different patients, in

health

and disease, both in

diagnosis and in

following treatment.

2. Solve problems

according to available

data.

3. Define, priories and

manage problems.

3. Use common

antimicrobial agents

and other antimicrobial

strategies effectively

and efficiently.

3. Participate in

scientific research.

4. Analyze, interpret,

objectively evaluate and

priories information,

recognizing its limitations.

4. Interpret the result

reports in different

specialty.

4. Evaluate risks in


5. Demonstrate insights

into research and scientific

methods through:

a. Understanding and

clinical appreciation of

methodology.

b.Formulating research

questions that are

relevant to medicine.

c.Choosing and

application of appropriate

quantitative and

qualitative

methodologies.

d. Recognition of the

importance of collecting

analyzing and

interpreting data.

e. Recognition of the

relationship between

evidence, audit and

5. Develop an evidence-

based approach to the

study of clinical

pathology.

5. Develop plans to

improve performance

and encourage evidence

based learning and

practice.


12

observed variation in

clinical practice.

6. Exhibit creativity/

resourcefulness in their

professional learning,

scientific endeavour and

clinical practice.

6. Encourge creativity

in profissional practice

7. Recognize and cope

with uncertainty by:

a. Accepting that

uncertainty is unavoidable

in the practice of medicine.

b. Using appropriate

intellectual strategy to deal

with uncertainty when it

arises.

: . مهارات مهنية وعمليةأ.ج


امج نلبزلاألكاديميت


للبزنامج والتى تتىافق مع المعاييز

ألكاديميت القياسيت ا

(ARS)

Benchmark

األكاديميتالمعاييز

لجامعت كامبزيدج

(NARS)

المعاييز القىميت

األكاديميت القياسيت

لبزامج قطاع العامت


الدكتىراه(

Clinical Hematology

Clinical Immunology


Clinical Chemistry

By the end of the program

the graduate according to

his specialty should be

able to:

1. Convert results from

one unit format to another

using the SI system.

By the end of the

program the

graduate should be

able to:

1. Understand how

research and

inquiry are used to

create and interpret

new knowledge in

the field.

By the end of the

program the

graduate should be

able to:

1. Best apply the

basic and recent

skills in

professional

practice.

2. Determine the missing

variable when either the

pK and pH or the pK and

concentration of the weak

acid and its conjugate base

2. Write and

evaluate

professional

reports.


11

are given using the

Hendrson – Hasselbalch

equation.

3. Analyze the data given

in a CBC or Bone Marrow

report.

3. Evaluate and

develop methods

used in different

clinical

investigations.

4. Define different types of

anticoagulants and their

optimal concentrations.

4. Use the

technological

methods in

professional

practice.

5. List different types of

microbiological cultures.

5. Instruct plans for

developing

professional

practice.

6. State different types of

immunological techniques.

7. List the types and

discuss the proper use of a

centrifuge, analytical

balance, and glassware for

diluting concentrated

substances.

8. Differentiate the type of

pipette when an actual

pipette or its description is

given.

9. Apply two ways to

calibrate a pipetting

device.

10. List the proper

drawing order for

collection tubes.

11. Identify the additive

preservative if present

when give a collection

stopper color.


12

:.ب. مهارات عامةج

المقزراث التى تحقق

امج نلبزلالمعاييز األكاديميت


للبزنامج والتى تتىافق مع

ألكاديميت القياسيت المعاييز ا

(ARS)

Benchmark


كامبزيدج

(NARS)

المعاييز القىميت األكاديميت

لبزامج قطاع العامت القياسيت


الدكتىراه(

Clinical Hematology

Clinical Immunology

Clinical

Microbiology

Clinical Chemistry

By the end of the


should be able to:

1. Communicate

effectively with teaching

staff, colleagues and the

community.

By the end of the


should be able to:

1. Lay the basis for life-

long learning of

integrated clinico-

pathological features of

disease.

By the end of the


should be able to:

1.Communication

effectively using

different

methods.

2. Demonstrate

appropriate attitude

towards teaching staff,

colleagues and patients.

2. Acquire training in

generic and transferable

research skills including

the critical evaluation of

current research and

methodologies and the

preparation of research

reports and applications.

2. Use information

technology in developing


3. Use information

technology.

3. Apply methods of

teaching and evaluation

of students.

4. Do good control of

timing.

5. Perform continuous

self teaching.

6. Present information

clearly in written,

electronic and oral form.

7. Communicate ideas

and arguments

effectively.

8. Apply the principles


13

of scientific research.

9. Deal with uncertainty

and work within a

changing environment.

10. Teach effectively

and act as a monitor to

others.

11. Communicate

effectively with

individuals regardless of

their social, cultural or

ethnic background or

their disabilities

للمعايير القومية األكاديمية MD in Clinical and Chemical Pathologyبرنامج نسبة تغطية - :لبرنامج الدكتوراهالقياسية العامة

% 100الفهم =المعرفة و -أ

% 100 = المهارات الذهنية -ب

% 100= المهارات المهنية والعملية -ج أ

% 100 = المهارات العامة -ج ب

ـ هيكل ومكونات البرنامج : 6

weeks 60أ ـ مدة البرنامج :

الساعات المعتمدة الكود المقررات البند ساعة 32 أربعة فصول دراسية وتتضمن: مقررات التخصص

CPAT 701 6 ضرات نظريةامح Seminars CPAT 702 8اجتماع عممى االشتتتتراى فتتتى اجتتترات جميتتتل التحاليتتتل الخاصتتتة

بتخصتتتتتتتتتتتص الطالتتتتتتتتتتت : يتتتتتتتتتتتت اختيتتتتتتتتتتتار أحتتتتتتتتتتتد رستتتتتتالة التخصصتتتتتتات ابتيتتتتتتة تبعتتتتتتا لموضتتتتتتوع

16


14

الدكتوراه: CPAT 703 امراض الد CPAT 704 المناعة CPAT 705 الميكروبيولوجيا اإلكمينيكية CPAT 706 الباثولوجيا الكيميائية

ساعة 15 تسجل بيا األنشطة المختمفة ومنيا: كراسة األنشطة حضور المؤتمرات والندوات الطبية ة زة المختمفتة المتطتور دورات تدريبية عمى األجي

مثتتتتتل جيتتتتتاز التتتتتتدف الخمتتتتتو وتفاعتتتتتل البممتتتتترة FISHوالتسمسمى

Seminarsتقدي الحديث فى التخصص فى ساعة 15 رسالة الدكتوراه

ساعة 62 االجمالى

ب ـ هيكل البرنامج :

( 60مالى ) ( إج 31( عملى ) 29الساعات المعتمدة : نظرى ) ـ عدد

( 60( إجمالى ) 0( إختيارى ) 60إجبارى )

% ( 100 ( نسبة ) 1 ـ مقررات علوم التخصص : عدد )

د ـ مقررات البرنامج :

MD in Clinical and Chemical Pathology البرنامجفى المستوى الثانى / السنة الثانية 1د ـ


15

ـ إجبارى : 1

عدد إسم المقرر كود المقرر الوحدات

النتائج التعليميت المستهدفت التي يتم عدد الساعات اإلسبوعية

تغطيتها

إجمالى عملى نظرى

CPAT 703

Clinical

Hematology 30 3.5 8 11.5 All points cover the

ILOS

CPAT 704

Clinical

Immunology 30 3.5 8 11.5 All points cover the

ILOS

CPAT 705

Clinical

Microbiology 30 3.5 8 11.5 All points cover the

ILOS

CPAT 706

Clinical

Chemistry

30 3.5 8 11.5 All points cover the

ILOS

15 رسالة الدكتوراه

: ـ محتويات المقررات 7

CPAT 703ـ كود المقرر :

Clinical Hematologyـ اسم المقرر :


16

ـ المحتويات :

عدد محاضرة سيمينار دروس عملية الساعات

الموضوع

7 7 12.25 Stem cell hemopoiesis.

RBCs and Anemia

9 9 15.75 Red cell memberane, Metabolism & Hb

synthesis.

5 5 8.75 Iron metabolism & its disorders

2 2 3.5 Megaloblastic anemia.

4 4 7 Aplastic anemia&BM failure

12 12 21 Hemolytic anemia

Immunological basis:

3 3 5.25 Spleen& Mechanism of phagocytosis

3 3 5.25 Molecular basis of leukemia and

lymphoma.

4 4 7 B &T cell ontogeny

Acute Leukemia

4 4 7 Acute myeloid leukemia

3 3 5.25 Acute lymphoblastic leukemia

Lymphoma

2 2 3.5 Hodgkin Lymphoma

2 2 3.5 Non -Hodgkin Lymphoma

2 2 3.5 Plasma cell dyscresias& MM

4 4 7 Lymphoproliferative Disorders

5 5 8.75 Myeloproliferative Disorders

1 1 1.75 M.D.S

Homeostasis

8 8 14 Physiology of Normal Homeostasis

6 6 10.5 Congenital& Acquired Coagulation

Disorders


17

6 6 10.5 Congenital& Acquired Platelet Disorders

6 6 10.5 Thrombosis,Thrombolysis &Antiplatelts.

3 3 5.25 Blood transfusion

2 2 3.5 Monocyte& Macrophage& related

disorders

2 2 3.5 Stem cell transplantation

2 2 3.5 Non malignant disorders of granulocyte

1 1 1.75 Haematological aspect of systemic disease

1 1 1.75 Neonatal hematology

2 2 3.5 Immunodeficiency diseases

2 2 3.5 Flowcytometry

2 2 3.5 Histocompatibility

4 4 7 Immunohematology

15

Practical hematology: I-Specimen collection and handling & Basic

hematological tecqniqes

35 2- Complete blood Count

6 3- ESR

12 4- Preperation and staining of peripheral &

Diffrential leucocytic count

15 5- RBCs morphologoy in health &disease

12 6- wBCs morphologoy in health &infection.

12 7- Reticulocytic count

6 8- Preperation &staining of bone marrow

film

9- Bone marrow morphology:

24 a-Hematopoiesis

18 10-Deficiency anemias.

3 1 1-Iron overload &Sideroblastic anemias.

30 12– Investigations of hemolytic anemia:


18

9 13-Case study on hemolytic anemia

18 14-Blood Banking Testing:

15- Acute Leukemia (Morphology)

15 - AML.

9 - All.

9 Case study on Acute Leukemia

15 17- Chronic Myeloproliferative Disorders:

15 -Case Study

21 18- Chronic Lymphoproliferative Disorders:

6 -Case study

12 19-Infectious mononucleosis

6 20- Plasma cell dyscrasis &MM

6 21- Aplastic anemia

22- Bone Marrow Morphology:

9 - Normocellular BM

9 - Hypercellular BM

9 - Hypocellular BM

12 -Case study

6 - ITP

6 - MQ,Mast cells , BM giant cells

6 - MDS

15 - ALL in BM

15 - AML in BM

6 -Pure red cell aplasia

15 - Bone Marrow counting & report

15 -Case Study

30 23- Coagulation Profile:


19


Clinical Immunologyـ اسم المقرر :

ـ المحتويات :

محاضرة سيمنار دروس عمليةعدد

الساعات الموضوع

1 2 2.5

General immunology:

1-Immune system (lymphocytes &

lymphoid tissues)

1 2 2.5

2-immunity: -Innate immunity: Cells of innate immunity

1 2 2.5 Innate immune response

1 2 2.5

-Acquired immunity : Cells of acquired immunity

1 2 2.5 Acquired immune response

1 2 2.5

3-Antigen presentation and major histocompatibility complex -Antibodies and antigen

1 2 2.5 -Antigen processing

3 4 6 4-Immunoglobulins & immunoglobulin gene.

3 4 6 5-B-cell development & the humoral immune response.

3 4 6 6-T-lymphocytes & natural killer cells

3 4 6 7-cytokines & chemokines -Cytokines of innate immunity

3 4 6 -Cytokines of acquired immunity

3 4 6 -Chemokines


22

1 2 2.5

8-Complement & kinin.

-Classical pathway

1 2 2.5 -Alternative pathway

1 2 2.5 -MBL pathway

1 2 2.5 -Complement inhibitors

3 4 6 9-The mucosal immune system.

3 4 6 10-immunization

3 4 6 11- Allergy desensitization

3 4 6 12-immunosuppressive therapy

3 4 6

Special immunology: 1-Immuno deficiency disorders -B cell immunodeficiency

3 4 6 -T cell immunodeficiency

2 4 5 -Combined immunodeficiency

2 4 5 -Complement immunodeficiency

2 4 5 -Phagocytes immunodeficiency

3 2 4.5 2-Rheumatic diseases -SLE

3 2 4.5 -RA ,Other arthritis

3 2 4.5 -Scleroderma , MCTD

2 2 3.5 -Other rheumatic


21

3 4 6 3-Mechanism of tumor immunology

2 2 3.5 4-Hypersensitivity reaction. -Atopic diseases

2

2

3.5 -Anaphylaxis

1 2 2.5 -Immune complex allergic diseases.

1 4 4 -Cell mediated hypersensitivity diseases.

1 2 2.5 -Drug allergy

2 4 5 5-Immunity to infection -Bacterial diseases

2 4 5 -Viral diseases

2 4 5 -AIDS

2 4 5 -Fungal diseases

2 4 5 -Parasitic diseases

2 4 5 -Spirochetal diseases

2 6 6.5 6-Endocrine disease

2 4 5

7-Clinical Transplanation

-Kidney transplantation

2 4 5 -Liver transplantation

2 4 5 -BM transplantation

2 4 5 -Rejection


22

4 2 10

Practical immunology: I-clinical laboratory methods for detection of Ag & Ab:

1-Immundiffusion

4 2 10 2-Electro pharesis & immunoelectrophoresis

4 2 10

3-Binder -ligand assay:-

a-Radioimmunoassay

4 2 10 b-ELISA

4 2 10 c-Western blot (WB)

4 2 10 d-Microparticle enzyme immunoassay (MEIA)

4 2 10

4-Immunohistochemical techniques:-

a-Immunofluorescence

8 4 20 b-other immunohistochemical techniques

8 4 20 5-Agglutination.

8 4 20 6-Complement assays

8 4 20

II-Clinical laboratory methods for detection of cellular immunity -Laboratory tests for B cells

8 4 20 -Laboratory tests for T cells

12 6 30

III-Molecular genetic techniques for clinical analysis of the immune system. -PCR

12 6 30 -FISH

12 6 30 -Micoarray


23

12 6 30 -Sequencing

12 6 30 -Others

12 6 30

IV-Histocompatibility testing

-Serological HLA typing

12 6 30 -Molecular HLA typing

12 6 30 -MLC

12 6 30

V-Laboratory evaluation of

immuncompetence

8 4 20 VI-Blood banking

8 4 20 VII- Immunhematology


Clinical Microbiologyـ اسم المقرر :

المحتويات : ـ

عدد دروس عمليت

المحاضزاث

المىضىع عدد الساعاث

2 2 4 Introduction to Microbiology

2

2 4 Cell structure

2

2 4 Classification of bacteria

2

2 4 The growth –survival and death of

microorganisms

2

2 4 Microbil metabolism

2 4 6 Microbil Genetics

2

2 4 Pathogenesis of bacterial infection


24

2

4 6 Antimicrobal chemotheraby

2

2 4 Normal microbial flora

2

2 4 Spore forming Gram positive bacilli

2

2 4 Non Spore forming Gram positive bacilli

12

4 8 Gram +ve cocci (Staphylococci, Streptococci

18

6 12 Enteric Gram negative rods

8

8 16 Gram negative bacteria

2

2 4 Unusual bacterial

pathogens(Legionella,bartonella& others)

2

4 6 Mycobacteria

2

2 4 Anaerobic bacteria

2

3 2 4 Spiral microorganism

2

2 4 Cell wall defective bacteria

2

2 4 Rickettsia

2

2 4 Chlamydiae

2

2 4 General properties of viruses

2

2 4 Pathognesis and control of viral disease

2

2 4 Laboratory diagnosis of viral infection

2

2 4 Parvoviruses

2

2 4 Adenoviruses

2

4 6 Herpesviruses

2

2 4 Pox viruses

2

2 4 Hebatitis viruses

2

2 4 Picorna viruses

2

4 6 Orbiviruses,Coltiviruses,calciviruses&Astro

viruses

2

2 4 Arthropod borne viruses

2

2 4 Coronaviruses


25

2

2 4 Rodent borne viruses

2

2 4 Slow viruses infection

2

2 4 Orthomyxo viruses

2

22 2 4 Para myxo viruses

2

2 4 Rabies viruses

2

2 4 Human cancer viruses

2

4 6 AIDS

2

2 4 Antiviral drugs

2

2 4 General properties & classification of fungi

2

2 4 Growth & isolation

2

2 4 6 Laboratory diagnosis of fungi

12

4 8 Mycosis(superficial, cutaneous&subcutaneous)

2

2 4 Opportunistic Mycosis

2

2 4 Endemic Mycosis

2

2 4 Hyper sensitivity of fungi&mycotoxin

2

2 4 Antifungal chemotheraby

2

2 4

Resistance to antifungal agents

2

2 3 Clinical correlation

2

4

Practical classes

Overview &General consideration

3

6 Laboratory consideration

5

10 Laboratory safety

10

20 Specimen management

10

20 Role of Microscopy

5

5 10 Staining

4

8 Traditional Cultivation&Identification


26

5

10 Immunochemical methods used for organism

detection

5

10 Serologic diagnosis of infectious disease

5

10 Principles of Antimicrobial action

&Resistance

8

16 Laboratory Methods &Strategies of

Antimicrobial Susceptibility testing

6

12 Overview of Bacterial identification Methods

&Strategies

5

5 10 Bacterial identification flow charts

6

12 Gram +ve cocci

4

8 Listeria,corynebacterium

1

2 Bacillus & similar organisms

2

4 Erythipflothrix, Lactobacillus

1

2 Nocardia

10 20 111

Enterobacteriaceae

4

8 Pseudomonas

4

8 Acinitobacter ,uncommon Gram negative

bacteria

2

4 Eikenella

12

24 Gram negative bacteria

3

6 Campylobacter,Helico bacter and related

bacteria

1

2 Unusual bacterial

pathogens(Legionella,bartonella& others)

4

8 Mycobacteria

6

12 Obligate intracellular &nonculturable Bacterial

Agents

3

6 Cell wall defective bacteria:

Mycoplasma

6

12 Anaerobic bacteria

2

4 Laboratory Methods in Basic Virology


27

4

8

Laboratory Methods in Basic Mycology

4

4 8 Laboratory physical Design

3

6 Meningitis&other infecton of the central

nervous system

5

10 Blood stream infections

2

4 Infections of the eyes&ears

4

8 Gastro intestinal infections

4

8 Respiratory infections

4

8 Urinary tract infection

4

8 Genital tract infection

3

6 Skin&Soft tissue infection

15

30 Quality in the cinical microbiology

20

40 Infection control

3

6 Automation in microbiology

5

10

Chemoprophylaxis

14

28 Current resistant strains proplems

(MRSA,VRE,pneumococci-MDR TB ESBL).


Clinical Chemistryـ اسم المقرر :


28

:ـ المحتويات

سيمنار دروس عمليت محاضزة

المىضىع عدد الساعاث

26 12 12 73 H Enzymology

-General enzymology

-Pancreatic enzymes

-Liver enzymes

-Cardiac enzymes

-Prostatic enzymes

-Muscle enzymes

-Enzymes as tumor markers

-Urinary enzymes

26 12 12 73 h Endocrinology

Anterior pituitary hormones:-

GH :

Prolactin:

Thyroid hormones-

TSH,T3,T4,fT3,fT4

Adrenal cortex hormones-

glucocorticoides,

mineralocorticoids &

androgens

20 10 8 56h Diabeted mellitus and

hypoglycemia

- Chemistry of carbohydrates

- Diabetes mellitus

- hypoglycemia

20 10 8 56 Lipids & lipoproteins

- lipids in blood Types of

circulatory

-Types of lipoproteins

28 14 14 80:30 h nsInstrumentatio

Spectrophotometric

techniques

Electrochemical techniques

electrophoresis

Chromatography

Mass Spectrometry

Osmometry.

Immunoassay


29

Turbidimetry & *

Nephlometry

,ELISA ,IRMA

EMIT,CEDIA,FIA,etc

Automation

16 8 8

46 h

nal functionRe

Understand the normal

function of the kidney

Understand evaluation of

renal function

16 8 8 46 h Liver function tests

Bilirubin ,

Enzymes ALT, AST. ALP,

GGT, 5'N

Diagnosis of different liver

diseases

16 8 8 46 h Serum proteins

Albumin

globulin proteins-1-phaAl

globulin -2-Alpha

, proteins

Gamma globulin

Urine proteins

16 8 8 46 h Amino acid

metabolism

PKU,tyrosinemia,alkaptinuria

,albinism,etc

12 6 6 34:30 h Tumor markers

- AFP, HCG,CEA,etc

14 6 6 38:30 h Calcium , phosphorus & Mg

Ca homeostasis

hypercalcemia

Hypocalcemia

Hypophosphatemia

Hyperphosphatemia

Hyper & hypomagnesemia

12 6

6 34:30 h

Acid base balance :

buffering systems

Role of the lung & kidney in


32

acid base balance

Acid Base Acidosis &

Balance

pH alkalosis

4 4 4 15 h Pregnancy & antenatal

screening

fetoplacental unit, effect of

pregnancy on biochemical

tests. complications

4 4 4 15 h Chemical pathology of

paediatrics & geriatrics

pediatrics reference range

diagnosis of biochemical

disturbances in the

neonate and early

childhood

4 4 4 15 h Therapeutic drug monitoring

& Chemical toxicology

interpretation of TDM

Understand

methodology of TDM

4 4 4 15 h Genetic and DNA based

technology

DNA technology

Application of DNA

technology in clinical

chemistry

الالئحة(:) طبقاً لما هو مذكور فى بالبرنامج االلتحاقـ متطلبات 8

أو العمتتتو الطبيتتتة يشتتتترط لقيتتتد الطالتتت لدرجتتتة التتتدكتوراه فتتتى الطتتت أو الجراحتتتة (:23مـــادةاألساستتية أو يكتتون حاصتتد عمتتى درجتتة الماجستتتير فتتى متتادة التخصتتص بتقتتدير جيتتد

ع أو عمتى درجتة معادلتة ليتا متن معيتد عممتى 2 2عمى األقل متن إحتد جامعتات ج 2أخر معترف بو من الجامعة


31

الدراسة لنيل الدكتوراه سنتان ونصف موزعة كاآلتى:مدة :ستتاعات معتمتتدةن ومتتن يرستت 6عمتتو أساستتية فصتتل دراستتى لمتتدة ستتتة شتتيور جــزأ لول

2بعيد مادة الرسو فقط :ن ستاعة معتمتدة يستتوفى خدليتا 39ثدث فصول دراسية لمدة سنة ونصتف الجزأ الثانى

تا اجتتتتاز االمتحتتتان الطالتت الستتتاعات المعتمتتدة ثتتت يستتم لتتتو بالتقتت د المتحتتتان التحريتتر واجالتحرير بنجاح يح لو التقد التى االمتحتان الشتفيى والعممتى اإلكمينيكتى ختدل شتير متن

2تاريخ االمتحان التحرير ساعة معتمدة(: 15رسالة بامتحتان شتامل فتى نيايتة كتل أربتل فصتول دراستية تنتيت تبدأ الدراسة عنتد بدايتة التستجيل

الجتتزت األول بنجتتاح يستتم لتتو بتستتجيل رستتالة لمتتدة أربعتتة تاالمتحانتتايتتاز الطالتت بعتتد اجتفصول دراسية تبدأ عند بداية الفصل الدراسى الثانى وتناقش بعتد مترور عتامين عمتى األقتل متتن تتتاريخ تستتجيل الرستتالة عمتتى أن تكتتون المناقشتتة بعتتد ستتتة أشتتير عمتتى األقتتل متتل اجتيتتاز

2كية والشفيى االمتحان الشاملناالمتحان التحرير واإلكميني 0يمنح الطالب الدرجة بعد مناقشة الرسالة واجتياز االمتحان الشامل

لمقيتتد لدرجتتة التتدكتوراه متترتين فتتى الستتنة ختتدل شتتيى متتارس واكتتتوبر متتن كتتل يكتتون التقتتد 2عا

ـ القواعد المنظمة إلستكمال البرنامج : 9

كتوراه فتتتى الطتتت أو الجراحتتتة أو العمتتتو الطبيتتتة يشتتتترط فتتتى الطالتتت لنيتتتل درجتتتة التتتد (:24مـــادة األساسية ما يمى:

2حضور المقررات الدراسية بصفة مرضية طبقا لمساعات المعتمدة

أن يقتو ببحتث فتى موضتتوع تقتره الجامعتة بعتتد موافقتة مجمتس الكميتة والقستت لمتدة ستنتان عمتتى 2األقل

2د مناقشة عمنية لمرسالةأن يتقد بنتائج البحث فى رسالة تقبميا لجنة الحك بع

دورة –اجتيتتتاز الطالتتتت ثدثتتتتة دورات فتتتى الحاستتتت ابلتتتتى دورة فتتتى مقدمتتتتة الحاستتتت ابلتتتتى 2وتلى قبل مناقشة الرسالة 2دورة فى تطبيقات الحاس ابلىن –تدريبية "متوسطة"


32

وحتتدة وتلتتى قبتتل مناقشتتة مناقشتتة 522ال يقتتل عتتن بمستتتو لالتتتو يفتتاجتيتتاز الطالتت اختبتتار 2لرسالةا

أن يجتتتتتاز بنجتتتتاح االختبتتتتارات التحريريتتتتة واإلكمينيكيتتتتة والشتتتتفيية المقتتتتررة وفقتتتتا لمتتتتا ىتتتتو مبتتتتين 2بالدئحة

2عمى الطال أن يقيد أسمة لدمتحان قبل موعدة بشير عمى األقل (: 25مادة يشتتترط لنجتتاح الطالتت فتتى امتحتتان التتدكتوراه الحصتتول عمتتى الحتتد األدنتتى لمنجتتاح فتتى (:26مــادة

جميل االختبتارات المقتررة وفتى كتل جتزت متن أجزاتىتا عمتى حتدة تلتى بطختت المتوستط لتقتديرات االمتحان تالمقرراأعضات المجنة إتا رس الطال فى أ مقرر من

لمتن -كتوراه فتى شتير نتوفمبر ومتايو متن كتل عتا : يعقد االمتحان التحرير لدرجتة التد(27مادة 2يجتاز االمتحان التحرير فى نفس الدور يتقد االمتحان الشفيى واإلكمينكى والعممى

أن يبقى مقيتدا لدرجتة التدكتوراه ألكثتر متن أربتل ستنوات دون أن يتقتد لمطال ال يجوز (:28مادةطالتت ميمتتة لمتتدة ستتنتين فتتى حالتتة قبتتول لمناقشتتة الرستتالة ويجتتوز لمجمتتس الكميتتة أن يعطتتى ال

2العتر تضتتتتاف درجتتتتات التحريتتتتر ووصتتتتف الحالتتتتة لبعضتتتتيا ويعتبتتتتر النجتتتتاح والرستتتتو فتتتتى (: 29مــــادة

% عمتتى األقتتل متتن الدرجتتة النيائيتتة لمتحريتتر ن ومتتن يتتنج فتتى 62المجمتتوع الكمتتى لمتحريتتر الشتتفوية والعمميتتة وعنتتد االمتحتتان التحريتتر يصتترح لتتو بتتدخول بتتاقى االمتحانتتات اإلكمينيكيتتة و

2الرسو يعيد الطال االمتحان الشفو واإلكمينيكى 2ال يح لمطال التقد لدمتحان التحرير أكثر من أربل مرات 2موضوع الرسالة والمادة أو المواد االختيارة الدكتوراهتبين فى شيادة (: 30مادة الدراستتية التتتى تتتدرس لنيتتل درجتتة التتدكتوراه تبتتين الجتتداول فتتى البتتا الختتامس المقتتررات (:31مــادة

2االختبارات التحريرية واإلكمينيكية والشفوية طبقا لمساعات المعتمدة

ـ وسائل تقييم مخرجات التعلم المستهدفة من البرنامج : 10


33

10- Students Assessment methods:

ـ طرق تقويم البرنامج : 11

العينة الوسيلة القائم بالتقويم م

االستبيان طالب السنة النهائية 1

الخريجون 2

أصحاب العمل 3

مقييم خارجى 4

طرق أخرى 5

مخرجات التعلم المستهدفة الوسيلة م

Written examination To assess knowledge & intellectual skills.

Oral examination To assess knowledge, intellectual skills &

General & transferable skills

Practical examination To assess knowledge, intellectual skills,

professional General & transferable skills

MCQ examination To assess knowledge & intellectual skills.


34

: الملحقات

Clinical Microbiology: توصيف مقرر 1ملحق

Clinical Immunology: توصيف مقرر 2ملحق

Clinical Chemistry: توصيف مقرر 3ملحق

Clinical Hematology: توصيف مقرر 4ملحق

لبرامج قطاع الدراسات العليا (NARS): المعايير القومية األكاديمية القياسية5ملحق

الدكتوراه( -الماجستير -)الدبلومات

Benchmark (ARS)6ملحق

University of Cambridge. School of clinical medicine. Addenbrooke’s

hospital. Clinical pathology course.

منسق البرنامج رئيس القسم عميد الكلية

أ.د/أحمد جودة الجزار أ.د/ منى الطوخى أ.د/ نيفين عبدالحفيظ

md in clinical and chemical pathology - bu...اـهنب ةـعماج بطا ةي 2 in the...

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