innovation for impact: a collaborative venture>90% fail in the first 5 years 95% of all medical...
TRANSCRIPT
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Innovation for Impact: A Collaborative Venture
Kristian R. Olson MD, MPH, DTM&H
CIMIT Global Health Initiative Program Leader
Clinician Educator MGH; MGH Center for Global Health
Harvard Medical School
10 September, 2010
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To enhance the
effectiveness of health care providers
in low-income
settings with sustainable
technologies and enabling training
Mission
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19,943
1,178449 195
3,560
670
5,000
10,000
15,000
20,000
Technology Technology
+ Health
Technology
+ Health +
International
Technology Technology
+ Health
Technology
+ Health +
International
Source: Guidestar & Innovations in International Health at MIT
Standard Technology Initiatives Appropriate Technology
Initiatives
Landscape of Health and Technology
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>90% Fail in the First 5 years
95% of all medical equipment in
resource-limited settings are donated
Source: Malkin, R. Design of Health Care Technologies in the Developing World. Annu. Rev. Biomed. Eng. 2007.
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Invention, Adoption, and Access are essential
Components of “Innovation”
Adapted from:Laura Frost & Michael Reich, Access, Harvard U. Press; 2008.
AFFORDABILITY
Government
Affordability
Non-
Governmental
Agency
Affordability
End-user
Affordability
ADOPTABILITY
Global Adoption
National
Adoption
Provider
Adoption
End-User
Adoption
AVAILABILITY
Manufacturing
Forecasting
Procurement
Distribution
Delivery
Architecture
Access
Innovation
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Building Capacity
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Technology Serving as a
Marker for Medical Sophistication
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Local Evaluation and Participatory Development is Essential for Accuracy and End User Ownership
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Collaborative Team Building for
Prototype Development
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A ‘Need Doesn’t Equal a Market”
Creative Innovation is Necessary
Source: CIMIT and Design that Matters
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Clinical Users
Prospective
Buyers Manufacturers
and Distributors
Technology
Innovators
Partnerships are Essential for
Sustainable Device Development.
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HIV Monitoring Through Lensless
Imaging for Point-of-Care Testing
Source: Demirci Lab (BAMM), Harvard Medical School
*
*=Charge-Coupled Device
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Column with DNA bound.
Source: Klapperich Lab, Boston University and Innovations in International Health at MIT
SNAP: System for Nucleic Acid Processing
14Source: Pollock, N, Diagnostics for All, Boston, MA.
Colorimetric Cellulose Based Point-of-Care
Testing of Liver Injury
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7 Key Barriers to Effective
Global Health Technology Innovation:
1) Addressing the right question
2) Lack of a clear path to market (and capacity to
weather the development timeline)
3) Product management capacity and tech transfer
4) Inadequate and unprepared infrastructure
5) Clarity of target product profiles and associated incremental benefit (technology choice)
6) Regulatory approval and multiple National Regulatory Authorities
7) Accurate forecasting
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