206A ABSTRAeTS JACC Vol. 15, No. 2 February 1990:206A

INADgQUACY OP CDRRRNT CRITRRIA FOR PREDICYIffi HIGH RISK CORONARY ANGIoPLAsYY

Bruca A. Pergelson, M.D., Go Kyller, R.N., Alice Nicholas A. RUOCCO, Jr.,

.D., P.A.C.C., David P. Paxon, M.D., P.A.C.C. Boston University Medical Center, Boston, HA

The ability to predict patients (pts) at risk for plicrtions (C) associated 4th PTCA is of increased

rtance vith the availability of prophylactic bypass assist devices. Accordingly, ve prospectively classified 170 consecutive ptrr based on accepted criteria for risk

Y lNFAW CTURAL

Derek R. Boughner, ‘A.C.C.

., Ph.

Samaritun curd University 0 j Southern Cdi jornia,

provide the necessary additional damage for infarct ex~8nsion to occur.

EVALUATION OF VOLUME-CATACBOLAMINK CO FOR RIGHT VENTRICULAR MYOCARDIAL INFARCTION.

Kenichi A Ohida, M.D., Kinji Tsukada. M.D.. Ichir; Na~ao, M.D.. Ken Hirose, M.D..

saharii Tochigi ,

Yoshimura, Japan

M.D.,-Doirkyo Univ. of Med.;

To evaluate the beneficial effect of volume loading combined with catecholamine administration for right ventricular myocardial infarction (WI), we measured pulmonary blood volume (PBV) and cardiac output (CO) by means of intravascular dual ~aa~an~~tometry usin optic fiber catheter eystem, which we developed, in 8 mengrel dog8 with experimental RVI. RVI ~88 produced with right coronary occlusion by injection of sliced awn muscle cube8 via catheter. Six hour8 laters 1501~1 of saline was infused at a rate of lSml/min followed by %g/kg/min of dobutamine. PBV and CO were meaeured before producing RVI (CNT)# before (B) and after (S) saline infusion, and after DOB administration (D). Changes in PBV and CO were;

CNT B S D __~_1___~_~~-__1~_~___________________I_~~~

PBV 100x co

64-g 1 100%

69213X 82~16F 57213% 65210% 72+_14%*

+ = p<o.OS V8 G by ANOVA Thus ) volume loading alone failed to increa8e PEV

and CO. However, the volume loading combined with catecholamine administration benefited deteriorated right cardiac function and increased PBV even with RVI. Accordingly, an enhancement of left ventricular contraction by catecholamine is suggested to affect the right ventricle directly and mechanically.