he was like no other (in memoriam levon mikhailovich chailakhyan)

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ISSN 00063509, Biophysics, 2010, Vol. 55, No. 3, p. 505. © Pleiades Publishing, Inc., 2010. Original Russian Text © G.R. Ivanitsky, A.V. Kulikov, 2010, published in Biofizika, 2010, Vol. 55, No. 3, p. 553. 505 It is already a year that Levon Mikhailovich Chail akhyan, Corresponding Member of RAS, is not among us. One can rarely meet a man who would take so critically and ironically his own significance and the significance of all he has done in physiology and bio physics. Yet there was quite something to be proud of. He published more than 450 works in leading Russian and international journals, was awarded the medal of the AllRussia Physiological Society named after I.P. Pavlov, was a member of the European Academy of Sciences, but there’s too much to enumerate. One of the first Chailakhyan’s biophysical works considered a kind of cardiac arrhythmia (Wenckebach period). The next series of works was devoted to experi mental and theoretical analysis of complex excitable structures such as cardiac syncytium and nerve cell den drites. Together with S.A. Kovalev, V.V. Smolyaninov, Yu.I. Arshavskii, and M.B. Berkinblit he has shown that the specific features of the spread of excitation depend not only on the parameters of cell membranes but also on the geometry of the excitable structure. Many of his works were connected with the role of highly permeable cell–cell contacts in the function of nonexcitable tis sues. In particular, it has been shown that such contacts are important in embryogenesis. On the whole, the works in embryology came to be perhaps the most interesting in Chailakhyan’s research. Development of novel methods of cell fusion brought about a great achievement. Chailakhyan together with B.N. Veprintsev, T.A. Sviridova, and V.A. Nikitin were the first to have cloned a mammal, Masha the Mouse. The report of this feat was pub lished in 1987, ten years before the famous Dolly the Sheep. Apart of scientific work, Levon Mikhailovich paid much attention to pedagogical activity. For many years he has been reading lectures at the Chair of Physiology of the Biological Faculty and a special course on the physiology of excitable tissues at the Chair of Biophys ics of the Physical Faculty of MSU, he was Dean of the Training Center of Physiology and Biophysics at the Pushchino State University. The scientific interests of Levon Mikhailovich were not limited to purely laboratory research. He thought much over the general problems of brain function. A result of these cogitations was the monograph “Sources of the Origin of Mentality or Conscious ness” (1992). Levon Mikhailovich was a kind and joyful man, who deserved to be loved; he has left so much after him that we shall be learning from him for a long time. And it is not only his science, it is his attitude to friends and opponents, to nature, sports, feasts. He was a man of remarkable integrity, he could forgive anything, except errors in experiments. L.M. Chailakhyan was Director Organizer of the Institute of Theoretical and Experimental Biophysics, RAS in Pushchino, and then worked as its Director for 11 years more. Try to imagine a man heading one of the key Institutes of the Academy for so long and hav ing made no enemies—yet this was so. At the age of eighty he was younger at heart than many who have not turned fifty. All his conscious life Levon Mikhailovich toiled to the glory of our physiology and biophysics. Friends and colleagues will always remember this fascinating main—scientist, educator, and organizer of science. G.R. Ivanitsky and A.V. Kulikov He Was Like No Other (In Memoriam Levon Mikhailovich Chailakhyan) DOI: 10.1134/S0006350910030267 CHRONICLES

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Page 1: He was like no other (In memoriam Levon Mikhailovich Chailakhyan)

ISSN 0006�3509, Biophysics, 2010, Vol. 55, No. 3, p. 505. © Pleiades Publishing, Inc., 2010.Original Russian Text © G.R. Ivanitsky, A.V. Kulikov, 2010, published in Biofizika, 2010, Vol. 55, No. 3, p. 553.

505

It is already a year that Levon Mikhailovich Chail�akhyan, Corresponding Member of RAS, is notamong us. One can rarely meet a man who would takeso critically and ironically his own significance and thesignificance of all he has done in physiology and bio�physics. Yet there was quite something to be proud of.He published more than 450 works in leading Russianand international journals, was awarded the medal ofthe All�Russia Physiological Society named afterI.P. Pavlov, was a member of the European Academyof Sciences, but there’s too much to enumerate.

One of the first Chailakhyan’s biophysical worksconsidered a kind of cardiac arrhythmia (Wenckebachperiod). The next series of works was devoted to experi�mental and theoretical analysis of complex excitablestructures such as cardiac syncytium and nerve cell den�drites. Together with S.A. Kovalev, V.V. Smolyaninov,Yu.I. Arshavskii, and M.B. Berkinblit he has shown thatthe specific features of the spread of excitation dependnot only on the parameters of cell membranes but alsoon the geometry of the excitable structure. Many of hisworks were connected with the role of highly permeablecell–cell contacts in the function of non�excitable tis�sues. In particular, it has been shown that such contactsare important in embryogenesis.

On the whole, the works in embryology came to beperhaps the most interesting in Chailakhyan’sresearch. Development of novel methods of cell fusionbrought about a great achievement. Chailakhyantogether with B.N. Veprintsev, T.A. Sviridova, andV.A. Nikitin were the first to have cloned a mammal,Masha the Mouse. The report of this feat was pub�lished in 1987, ten years before the famous Dolly theSheep.

Apart of scientific work, Levon Mikhailovich paidmuch attention to pedagogical activity. For many years

he has been reading lectures at the Chair of Physiologyof the Biological Faculty and a special course on thephysiology of excitable tissues at the Chair of Biophys�ics of the Physical Faculty of MSU, he was Dean of theTraining Center of Physiology and Biophysics at thePushchino State University.

The scientific interests of Levon Mikhailovich werenot limited to purely laboratory research. He thoughtmuch over the general problems of brain function. Aresult of these cogitations was the monograph“Sources of the Origin of Mentality or Conscious�ness” (1992).

Levon Mikhailovich was a kind and joyful man,who deserved to be loved; he has left so much after himthat we shall be learning from him for a long time. Andit is not only his science, it is his attitude to friends andopponents, to nature, sports, feasts. He was a man ofremarkable integrity, he could forgive anything, excepterrors in experiments.

L.M. Chailakhyan was Director Organizer of theInstitute of Theoretical and Experimental Biophysics,RAS in Pushchino, and then worked as its Director for11 years more. Try to imagine a man heading one ofthe key Institutes of the Academy for so long and hav�ing made no enemies—yet this was so. At the age ofeighty he was younger at heart than many who havenot turned fifty.

All his conscious life Levon Mikhailovich toiled tothe glory of our physiology and biophysics. Friendsand colleagues will always remember this fascinatingmain—scientist, educator, and organizer of science.

G.R. Ivanitskyand A.V. Kulikov

He Was Like No Other(In Memoriam Levon Mikhailovich Chailakhyan)

DOI: 10.1134/S0006350910030267

CHRONICLES