8/3/2019 Hca240 Appendix c

1/1

Axia College Material

Appendix C

Immune Response and Hypersensitivity

Puncture Wound Multimedia Activity

After completing the Puncture Wound Multimedia Activity, complete the table below. List the fourevents of the inflammatory response covered in the activity in the order of occurrence. Rewritethe events in your own words, using vocabulary terms from Ch. 2 of the text.

Vascular Events in an Inflammatory ResponseEvents Simplified description of event Professional description of event

1st

Germs from the nail are introduced to theskin

An object punctures the skin, bacteriaenters and multiplies. Hyperemia will thencause neutrophils to line on the capillary

walls. This protects from microorganisms

2ndSurrounding cells leak fluid that affectsthe blood vessels

.Tissue that is damaged can releasehistamines in the body.

3rd

The fluid affecting the surrounding bloodvessels causes the release of other cellsinto the tissue

Histamine can cause the blood vessels toexpand. This allows plasma andneutrophils to move from the blood vesselsinto damaged tissue

4thAs the wounded part of the body reactsto the germs, certain cells destroy thesegerms

Polymorphs move to the bacteria by thechemotaxis and ingested. That destroysthe bacteria and toxins

Hypersensitivity

Give a brief description and example in your own words for each of the four types ofhypersensitivity presented in Ch. 2.

Hypersensitivity MatrixType of Hypersensitivity Description Example

Type I: Allergic/Anaphylactic .This hypersensitivity is triggeredby allergen binding to IgE on mastcells, which produce local severeinflammation or systemic severeinflammation

.allergic reaction tobee venom

Type II: Cytotoxic/Cytolytic IgM or IgG interacting with foreigncells to cause their destruction

incompatable bloodtransfusion

Type III: Immune Complex Antigens combine withantibodies,forming immunecomplexes

Farmers Lung causedby mold sporeinhalation

Type IV: Cell-mediated/Delayed Expose to an antigen results inactivation of a T-cell-mediatedimmune response

poison ivy

HCA 240