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Axia College Material
Appendix C
Immune Response and Hypersensitivity
Puncture Wound Multimedia Activity
After completing the Puncture Wound Multimedia Activity, complete the table below. List the fourevents of the inflammatory response covered in the activity in the order of occurrence. Rewritethe events in your own words, using vocabulary terms from Ch. 2 of the text.
Vascular Events in an Inflammatory ResponseEvents Simplified description of event Professional description of event
1st
Germs from the nail are introduced to theskin
An object punctures the skin, bacteriaenters and multiplies. Hyperemia will thencause neutrophils to line on the capillary
walls. This protects from microorganisms
2ndSurrounding cells leak fluid that affectsthe blood vessels
.Tissue that is damaged can releasehistamines in the body.
3rd
The fluid affecting the surrounding bloodvessels causes the release of other cellsinto the tissue
Histamine can cause the blood vessels toexpand. This allows plasma andneutrophils to move from the blood vesselsinto damaged tissue
4thAs the wounded part of the body reactsto the germs, certain cells destroy thesegerms
Polymorphs move to the bacteria by thechemotaxis and ingested. That destroysthe bacteria and toxins
Hypersensitivity
Give a brief description and example in your own words for each of the four types ofhypersensitivity presented in Ch. 2.
Hypersensitivity MatrixType of Hypersensitivity Description Example
Type I: Allergic/Anaphylactic .This hypersensitivity is triggeredby allergen binding to IgE on mastcells, which produce local severeinflammation or systemic severeinflammation
.allergic reaction tobee venom
Type II: Cytotoxic/Cytolytic IgM or IgG interacting with foreigncells to cause their destruction
incompatable bloodtransfusion
Type III: Immune Complex Antigens combine withantibodies,forming immunecomplexes
Farmers Lung causedby mold sporeinhalation
Type IV: Cell-mediated/Delayed Expose to an antigen results inactivation of a T-cell-mediatedimmune response
poison ivy
HCA 240