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    Choreographing couch, collimator

    an gan ry mo on n ra a on

    deliverCollaboration of the following people at MSKCC:

    Pengpeng Zhang

    Yingli YangGig Mageras

    Margie Hunt

    Jian in Xion

    Jie Yang

    Maria Chan

    Josh Yamada

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    in VMAT for paraspinal SBRT

    2nd

    project was Choreographing couch,

    VMAT

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    Collimator trajectory in VMAT for paraspinal SBRT

    Motivation

    Improve dosimetric qualityo Increase target coverage

    o

    Preserve better critical organ sparing

    Explore additional mechanical freedom

    IJROBP. 2010; 77(2):591-9.

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    Collimator trajectory in VMAT for paraspinal SBRT

    Optimize collimator trajectory based on

    S nchronize collimator rotation with MLC

    motion, gantry rotation, and dose rate

    modulation

    Development and evaluation in paraspinal

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    Collimator trajectory in VMAT for paraspinal SBRT

    Why collimator matters?

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    Determine collimator trajectory via

    Collimator trajectory in VMAT for paraspinal SBRT

    principle component analysis

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    Collimator trajectory in VMAT for paraspinal SBRT

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    Collimator trajectory in VMAT for paraspinal SBRT

    Paraspinal SBRT study

    1.Retrospective study following

    MSKCC paraspinal SBRT protocol

    2.Prescription dose: 24Gy to tumor,

    cord maximum dose

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    Collimator trajectory in VMAT for paraspinal SBRT

    All protocol constraints are met with all three plans

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    Dosimetr Results:

    Collimator trajectory in VMAT for paraspinal SBRT

    Coll-VMAT vs VMAT vs IMRT

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    -

    Collimator trajectory in VMAT for paraspinal SBRT

    Again, Why collimator angle

    ma ers

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    Collimator trajectory in VMAT for paraspinal SBRT

    e uce w

    Technique Average MUs

    Coll VMAT 5164

    VMAT 4868

    IMRT 13283

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    Collimator trajectory in VMAT for paraspinal SBRT

    ummary

    Coll-vmat provides an additional degreeof freedom

    Dosimetric quality of VMAT plans is as

    good or better as fixed gantry IMRT forparaspinal SBRT

    ord dose lower with oll VMAT than

    IMRT

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    Choreographing couch,

    gantry and collimator

    We develo ed a software to facilitate the selection and

    optimization of non-coplanar VMAT arcs

    e eva ua e e ec n que n e rea men o

    tumors

    IJROBP. 2011; 80(4):1238-47

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    Selecting couch/gantry trajectory

    PTVEye

    based on PTV/OAR areaoverlap

    Brainstem

    Cord

    cLgcL ,,

    i OARiPTVi

    i

    gcAgcA ,,

    ,

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    Target/OAR Overlap Map

    CA=-

    60;

    GA=-60

    CA=45;

    GA=100for particular patient

    CA=0;

    GA=-150

    CA=85;GA=60

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    Optimization of Couch/gantry Trajectory

    ,those with minimum overlap score.

    Algorithm must remove combos in the forbidden zone collisions areas

    Link and extend small arcs to create lon er arcs

    Smooth arcs to accommodate mechanical constraints and limitations

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    Adding optimized Collimator Trajectories

    137o

    80o

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    Non-coplanar VMAT Delivery Using

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    NS Radiotherapy Planning & Comparison

    Ten CNS cases, fourteen tumors, three with dose painting,

    Treatment techniques

    IMRT: 4-6 non-coplanar beams

    VMAT: 1-4 arc pairs (orthogonal collimator trajectories)

    Std-VMAT: static couch and collimator

    Tra-VMAT: d namic couch and collimator

    Evaluate:

    arge coverage

    maximum/mean dose to OARs.

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    Plan EvaluationTra Vmat

    an ar

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    TraTra--VMAT vsVMAT vs IMRT vs StdIMRT vs Std--VMATVMAT

    Tra-VMAT Std-VMAT IMRT

    PTV Dmin 94.1 16.4% 93.1 17% 87.9 18.1%

    ra ns em mean . . . . . .

    Chiasm Dmax 76.9 35.8% 78.5 36% 78.2 35.9%Chiasm Dmean 61.6 34.1% 64.2 34.1% 65.9 34.1%

    Optical nerve Dmax 57.1 33.3% 59.4 32.3% 63.4 30.6%

    Cochlea Dmax 50.9

    39.7% 52.3

    38.9% 59.3

    33.7%mean . . . . . .

    MU 614 419 622 446 1262 783

    ra n cm Brain V70%(cm3) 173 71 200 91 163 72

    (medianSTD)

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    SummarySummary

    Tra-VMAT vs IMRT

    Higher PTV minimum dose, lower dose to brainstem,chiasm, optical nerve, and cochlea

    improved treatment efficiency (by 50%)

    Tra-VMAT vs Std-VMAT Better target conformality (ie lower brain dose)

    Lower dose to brainstem, chiasm, and optical nerve

    Superior mechanical flexibility of TrueBeam transforms to

    better plan quality

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    Future endeavors at our intuition

    1) Jaw tracking change jaws per control point

    A) To reduce leakage between parked leaves in VMAT

    delivery.

    B) To reduce the need to split IMRT beams

    2) Target motion tracking

    A) Collimator trajectory to aid MLC target tracking.