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P://Guidelines/Oxygen Guidelines/June09 1 CLINICAL GUIDELINES Document No: *All Sites Prescription and Administration of Oxygen in Adults Version: 01 Approved by: Quality of Care & Patient Safety Sub- Group Author/lead responsible for Guidelines : Dr A L Chapman & Dr G Antunes, Consultants Chest Medicine Date Approved : 12 th May 2009 Review date: June 2011 Target audience: All Wards and Departments Amendments and Additions N/A Replaces/supersedes: N/A Associated Policies: Issue Date June 2009

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P://Guidelines/Oxygen Guidelines/June09

1

CLINICAL GUIDELINES

Document No:

*All Sites

Prescription and Administration of Oxygen in Adults

Version: 01

Approved by: Quality of Care & Patient Safety Sub- Group

Author/lead responsible for Guidelines :

Dr A L Chapman & Dr G Antunes, Consultants Chest Medicine

Date Approved : 12th May 2009

Review date: June 2011

Target audience: All Wards and Departments

Amendments and Additions N/A

Replaces/supersedes: N/A

Associated Policies:

Issue Date June 2009

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CONTENTS Page

1. Introduction

2. Aim

3. Prescribing, administering and monitoring oxygen & emergency situations

4. Exclusions

5. Specialist areas

6. Pre-Hospital care

7. Indications

8. Contra indications

9. Cautions

10. Transfer and transportation of patients receiving oxygen therapy

11. Peri-operatively and immediately post operatively

12. Nebulised therapy and oxygen

13. Normal oxygen saturation ranges

14. Administration protocol

15. Humidification

16. Implementation

17. Monitoring arrangements

18. Health and Safety

19. References

APPENDICIES

A. Critical illnesses requiring high levels of supplemental oxygen B. Serious illnesses requiring moderate levels of supplemental oxygen if the patient is hypoxaemic C. COPD and other conditions requiring controlled or low-dose oxygen therapy D. Conditions for which patients should be monitored closely oxygen therapy is not

required unless the patient is hypoxaemic E. Oxygen prescription for acutely hypoxaemic patients in hospital F. Example of local oxygen prescription chart G. Example of patient Alert Cards for those with previous respiratory acidosis H. Administering acute oxygen therapy I. Equipment used in the delivery of oxygen J. Personnel who may administer oxygen K. Flow Chart for oxygen administration L. Early Warning Observation Score Chart (Pages1 and 2) M. Early Warning Track and Triggers system / Graded Response Chart N. Codes for recording Oxygen Delivery on Early Warning Observation chart O. Humidification P. Health and safety

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1.0 Introduction

The administration of supplemental oxygen is an essential element of appropriate management for a wide range of clinical conditions; however oxygen is a drug and therefore requires prescribing in all but emergency situations. Failure to administer oxygen appropriately can result in serious harm to the patient. The safe implementation of oxygen therapy with appropriate monitoring is an integral component of the Healthcare Professional’s role.

2.0 Aim

The aim of this protocol is to ensure that:

• All patients who require supplementary oxygen therapy receive therapy that is appropriate to their clinical condition and in line with national guidance (BTS Guideline; Thorax, 2008).

• Oxygen will be prescribed according to a target saturation range. The system of prescribing target saturation aims to achieve a specified outcome, rather than specifying the oxygen delivery method alone.

• Those who administer oxygen therapy will monitor the patient and keep within the target saturation range.

3.0 Prescribing, administering and monitoring oxygen

3.1 Identifying appropriate target saturations

Guidance on identifying appropriate saturations for patients is provided for the medical staff and other prescribers in Appendices A, B C, D and E.

In summary oxygen should be prescribed to achieve a target saturation of 94-98% for most acutely unwell patients or 88-92% for those at risk of hypercapnic respiratory failure.

3.2 Prescribing oxygen on the drug chart

An oxygen section on the drug chart has been designed to assist prescription and administration. Oxygen should be prescribed in the designated section of the hospital prescription card (Appendix F) and the appropriate target saturation should be circled on the chart (or if target saturations are not indicated the relevant box should be ticked).

3.3 Administering oxygen

Once the target saturation has been identified and prescribed, guidance regarding the most appropriate delivery system to reach and maintain the prescribed saturation is provided for those administering oxygen in Appendix G, H and I. Personnel who may administer oxygen is shown in Appendix J.

3.4 Monitoring and recording oxygen

The patient's oxygen saturation and oxygen delivery system should be recorded on the bedside observation chart alongside other physiological variables as shown in Appendix L. This appendix also specifies the codes for oxygen delivery devices to

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be recorded on the observation chart. Patients should be monitored according to the Early Warning Track and Trigger system in Appendix M.

All patients on oxygen therapy should have regular pulse oximetry measurements. The frequency of oximetry measurements will depend on the condition being treated and the stability of the patient. Critically ill patients should have their oxygen saturations monitored continuously and recorded every few minutes whereas patients with mild breathlessness due to a stable condition will need less frequent monitoring.

Oxygen therapy should be increased if the saturation is below the desired range and decreased if the saturation is above the desired range (and eventually discontinued as the patient recovers). See section 14 and Appendix K for more details

Any sudden fall in oxygen saturation should lead to clinical evaluation of the patient and in most cases, measurement of blood gases.

Patients on oxygen should have their saturations recorded in line with the Trust’s minimum observation policy. (See Appendices L, M and N).

Patients should be monitored accurately for signs of improvement or deterioration. Nurses should also monitor skin colour for peripheral cyanosis and respiratory rate. Oxygen saturations of less than 90%, with or without oxygen, noisy or laboured breathing or respiratory rate of less than 8 or more than 25 should be reported immediately to the medical team, according to the Early Warning Track and Trigger system in Appendix M.

3.5 Emergency situations

In the emergency situation an oxygen prescription is not required. Oxygen should be given to the patient immediately without a formal prescription or drug order but documented later in the patient’s record.

All peri-arrest and critically ill patients should be given 100% oxygen (15 l/m reservoir mask) whilst awaiting immediate medical review. Patients with COPD and other risk factors for hypercapnia who develop critical illness should have the same initial target saturations as other critically ill patients pending the results of urgent blood gas results after which these patients may need controlled oxygen therapy or supported ventilation if there is severe hypoxaemia and/or hypercapnia with respiratory acidosis.

All patients who have had a cardiac or respiratory arrest should have 100% Oxygen provided along with basic/advanced life support.

A subsequent written record must be made of what oxygen therapy has been given to every patient alongside the recording of all other emergency treatment.

Any qualified nurse/ health professional can commence oxygen therapy in an emergency situation.

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4.0 Exclusions

• Patients admitted to specialist areas with a specialised oxygen prescribing policy (see section 5 - Specialist Areas below)

• Patients receiving oxygen as part of palliative care or patients on the end of life care pathway (in which case, the prescriber should tick the box ‘target saturations not indicated’ on the drug chart).

• Patients admitted for Long Term Oxygen Therapy assessment.

5.0 Specialist Areas

This protocol is for general use within general wards and departments. Where specific clinical guidelines are required for oxygen administration within specialist areas, (namely Critical Care areas, Paediatrics, Endoscopy and Theatres) they must be approved via the appropriate clinical governance forum. They should reflect wherever possible the principles within this protocol. Patients transferring from specialist areas must be transferred with a prescription for their oxygen therapy utilising target saturation, if the clinical indication is ongoing. If a patient transfers from an area not utilising the target saturation system, their oxygen should be administered as per the transferring area’s prescription until the patient is reviewed and transferred over to the target saturation scheme, which should occur as soon as possible.

6.0 Pre Hospital Care

The principles of this document should in addition apply to the pre hospital care setting. In order to aid this, patients who have demonstrated that they develop a respiratory acidosis with the administration of oxygen will be issued with alert cards upon discharge or in outpatients by a respiratory consultant. (see Appendix G) This will be individualised to the patients requirements and dictates that they have a lower target range of oxygen to minimise the risk of an iatrogenic respiratory acidosis occurring, unless the patient is deemed critically unwell (see Appendix A). Such patients should also be administered the appropriate venturi mask to take home in order to use when travelling to hospital by paramedic crews.

7.0 Indications

The rationale for oxygen therapy is prevention of cellular hypoxia, caused by hypoxaemia (low PaO2), and thus prevention of potentially irreversible damage to vital organs.

Therefore the most common reasons for oxygen therapy to be initiated are:

• Acute hypoxaemia (for example pneumonia, shock, asthma, heart failure, pulmonary embolus)

• Ischaemia (for example myocardial infarction, but only if associated with hypoxaemia (abnormally high levels may be harmful to patients with ischaemic heart disease and stroke).

• Abnormalities in quality or type of haemoglobin (for example acute GI blood loss or carbon monoxide poisoning).

Other indications include:

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• Pneumothorax – Oxygen may increase the rate of resolution of pneumothorax in patients for whom a chest drain is not indicated.

• Post operative state (general anaesthesia can lead to decrease in functional residual capacity with in the lungs (especially following thoracic or abdominal surgery) resulting in hypoxaemia (Ferguson 1999). There is some evidence to suggest a decreased incidence of post operative wound infections with short-term oxygen therapy following bowel surgery.

8.0 Contra-indications

There are no absolute contraindications to oxygen therapy if indications are judged to be present. The goal of oxygen therapy is to achieve adequate tissue oxygenation using the lowest possible FiO2. Supplemental O2 should be administered with caution in patients suffering from paraquat poisoning (BNF 2005) and with acid inhalation or previous bleomycin lung injury.

9.0 Cautions

9.1. Oxygen administration and carbon dioxide retention

In patients with chronic carbon dioxide retention, oxygen administration may cause further increases in carbon dioxide and respiratory acidosis. This may occur in patients with COPD, neuromuscular disorders, morbid obesity or musculoskeletal disorders. There are several factors which lead to the rise in CO2 with oxygen therapy in patients with hypercapnic respiratory failure and details are in the BTS guideline.

9.2. Other precautions/ Hazards/ Complications of oxygen therapy

• Drying of nasal and pharyngeal mucosa

• Oxygen toxicity

• Absorption atelectasis

• Skin irritation

• Fire hazard

• Potentially inadequate flow resulting in lower FiO2 than intended due to high inspiratory demand or inappropriate oxygen delivery device or equipment faults

10.0 Transfer and transportation of patients receiving oxygen

Patients who are transferred from one area to another must have clear documentation of their ongoing oxygen requirements and documentation of their oxygen saturation. If a patient transfers from an area not utilising the target saturation system (see specialist areas above) their oxygen should be administered as per the transferring areas prescription until the patient is reviewed and transferred over to the target saturation scheme, which should occur as soon as possible.

Patients requiring oxygen therapy whilst being transferred from one area to another should be accompanied by a trained member of the nursing staff wherever possible. If this does not occur, clear instructions must be provided for personnel involved in the transfer of the patient, which must include delivery device and flow rate.

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11.0 Peri-operative and immediately post operatively Pre-operative patients should have oxygen prescribed if needed following the usual procedure utilizing target saturations if stable or as high flow (15 l/min via reservoir mask) in case of unstable or emergency. Post-operative patients should have their oxygen prescribed by the anaesthetist responsible for the case. It will be at the discretion of the anaesthetists and surgeons responsible for the case to prescribe oxygen on a target saturation basis or on a time-limited instruction (e.g. Oxygen via simple mask at 4 l/min for 4 postoperative days and then review). There is evidence of overnight hypoxic periods after major surgery for several nights post general anaesthesia. The instructions will be documented on the anaesthetic record for the patient (last page, postoperative instructions) and will be prescribed on the patient’s drug chart. The instructions and prescription should be adhered to unless there is a change in patient condition. In this situation the doctor reviewing the prescription of oxygen should document clearly in the patients medical records the reason for this change.

12.0 Nebulised therapy and oxygen

When nebulised therapy is administered to patients at risk of hypercapnic respiratory failure (see Appendix C) if driven by oxygen this should be limited to a period of 6 minutes. In specific areas it may be more appropriate to use compressed air to reduce the risk of hyperoxygenation and worsening hypercapnia. If compressed air is use it will be necessary to maintain the target saturation between 88-92% using 1-4 litres via nasal prongs simultaneously.

All patients requiring 35% or greater oxygen therapy should have their nebulised therapy by oxygen at a flow rate of >6 litres/minute.

13.0 Normal Oxygen saturations

• In adults less than 70 years of age at rest at sea level 96% - 98% when awake.

• Aged 70 and above at rest at sea level greater than 94% when awake.

• Patients of all ages may have transient dips of saturation to 84% during sleep.

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14.0 Summary Oxygen Administration Protocol (and Weaning Protocol)

ACTION RATIONALE

All patients requiring oxygen therapy will have a prescription for oxygen therapy recorded on the patients drug prescription chart. N.B exceptions- see emergency situations

Oxygen should be regarded as a drug and should be prescribed. BTS National guidelines (2008). British National Formulary (2008).

The prescription will incorporate a target saturation that will be identified by the clinician prescribing the oxygen in accordance with the Trust's oxygen guideline

Certain groups of patients require different target ranges for their oxygen saturation, see Tables 1-4.

Certain groups of patients are at risk of hyperoxaemia, particularly patients with COPD.

The prescription will incorporate an initial starting dose (i.e. delivery device and flow rate)

To provide the nurses with guidance for the appropriate starting point for the oxygen delivery system and flow rate

The drug chart should be signed at every drug round

To ensure that the patient is receiving oxygen if prescribed and to consider weaning and discontinuation

Once oxygen is in situ the nurse will monitor observations in line with trust policy. All patients should have their oxygen saturation observed for at least five minutes after starting oxygen therapy. If a patient is receiving intermittent therapy they may be monitored at least 8 hourly.

To identify if oxygen therapy is maintaining the target saturation or if an increase or decrease in oxygen therapy is required

The oxygen delivery device and oxygen flow rate should be recorded alongside the oxygen saturation on the bedside observation chart.

To provide an accurate record and allow trends in oxygen therapy and saturation levels to be identified.

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Oxygen saturations must always be interpreted alongside the patients clinical status incorporating the early warning score.

To identify early signs of clinical deterioration, e.g. elevated respiratory rate

If the patient falls outside of the target saturation range, the oxygen therapy will be adjusted accordingly

The saturation should be monitored continuously for at least 5 minutes after any increase or decrease in oxygen dose to ensure that the patient acheives the desired saturation range.

To maintain the saturation in the desired range.

Saturation higher than target specified or >98% for an extended period of time.

• Step down oxygen therapy as per guidance for delivery

The patient will require weaning down from current oxygen delivery system.

See Appendix K

• Consider discontinuation of oxygen therapy

The patients clinical condition may have improved negating the need for supplementary oxygen

Saturation lower than target specified

• Check all elements of oxygen delivery system for faults or errors.

In most instances a fall in oxygen saturation is due to deterioration of the patient however equipment faults should be checked for.

• Step up oxygen therapy as per protocols in Appendix K. Any sudden fall in oxygen saturation should lead to clinical evaluation and in most cases measurement of blood gases

To assess the patients response to oxygen increase, and ensure that PaCO2 has not risen to an unacceptable level, or Ph dropped to an unacceptable level and to screen for the cause of deteriorating oxygen level (e.g. pneumonia, heart failure etc)

Monitor Early Warning Score for further clinical signs of deterioration

Patient safety

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Saturation within target specified

• Continue with oxygen therapy, and monitor patient to identify appropriate time for stepping down therapy, once clinical condition allows

• A change in delivery device (without an increase in O2 therapy) does not require review by the medical team.

(The change may be made in stable patients due to patient preference or comfort).

Oxygen delivery methods

The Trusts recommended delivery devices will be utilised to ensure a standardised approach to oxygen delivery, see Appendix I

Previous audits have demonstrated wide variations in delivery devices across clinical areas, potentially increasing the risk of adverse incidents

15. Humidification

Humidification may be required for some patient groups, especially “neck-breathing patients” and those who have difficulty in clearing airway secretions or mucus. See Appendix O.

16. Implementation

The BTS has appointed oxygen champions in all Trusts to help introduce the Guideline; Dr George Antunes and Angela Kelly for JCUH and Dr Alexander Chapman and Amy Kerr for FHN are the appointed oxygen champions within this trust.

All doctors should be taught about the oxygen policy. All nurses, nursing assistants and other healthcare professionals involved in prescribing or administrating oxygen should be taught about the oxygen policy.

Teaching aides are available on www.brit-thoracic.org/emergencyoxygen. A record of all those who have been taught will be kept.

17. Monitoring Arrangements

Audits will be performed in all clinical areas utilising audit proformas available on the BTS website.

The hospital will participate in the national audits organised by the BTS.

18.0 Health and Safety

Health and Safety issues are covered in Appendix P.

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19.0 References

• O’Driscoll B R, Howard L S, Davison A G. BTS guideline for emergency oxygen use in adult patients. Thorax 2008; 63: Supplement VI.

• Summary guideline for prescribing oxygen emergency oxygen in hospital.

Available on BTS website: www.brit-thoracic.org.uk/emergencyoxygen/

• Summary of prescription, administration and discontinuation of oxygen therapy.

Available on BTS website: www.brit-thoracic.org.uk/emergencyoxygen/

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A P P E N D I C I E S APPENDIX A Referenced from the British Thoracic Society

Critical illnesses requiring high levels of supplemental oxygen

• The initial oxygen therapy is a reservoir mask at 15 l/min.

• Once stable, reduce the oxygen dose and aim for target saturation range of 94-98%.

• If oximetry is unavailable, continue to use a reservoir mask until definitive treatment is available.

• Patients with COPD and other risk factors for hypercapnia who develop critical illness should have the same initial target saturations as other critically ill patients pending the results of blood gas measurements, after which these patients may need controlled oxygen therapy or supported ventilation if there is severe hypoxaemia and/or hypercapnia with respiratory acidosis.

Additional comments Grade of recommendation

Cardiac arrest or resuscitation

Use bag-valve mask during active resuscitation

Grade D

Aim for maximum possible oxygen saturation until the patient is stable

Shock, sepsis, major trauma, near-drowning, anaphylaxis,

Also give specific treatment for the underlying condition

Grade D

major pulmonary haemorrhage

Major head injury Early intubation and ventilation if comatose

Grade D

Carbon monoxide poisoning Give as much oxygen as possible using a bag-valve mask or reservoir mask. Check carboxyhaemoglobin levels

Grade C

A normal or high oximetry reading should be disregarded because saturation monitors cannot differentiate between carboxyhaemoglobin and oxyhaemoglobin owing to their similar absorbances.

The blood gas PaO2 will also be normal in these cases (despite the presence of tissue hypoxia)

COPD, chronic obstructive pulmonary disease; Pa02, arterial oxygen tension.

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APPENDIX B Referenced from the British Thoracic Society

Serious illnesses requiring moderate levels of supplemental oxygen if the patient is hypoxaemic

• The initial oxygen therapy is nasal cannulae at 2-6 l/min (preferably) or simple face mask at 5-10 l/min unless stated otherwise.

• For patients not at risk of hypercapnic respiratory failure who have saturation <85%, treatment should be commenced with a reservoir mask at 10-15 l/min.

• The recommended initial oxygen saturation target range is 94-98%.

• If oximetry is not available, give oxygen as above until oximetry or blood gas results are available.

• Change to reservoir mask if the desired saturation range cannot be maintained with nasal cannulae or simple face mask (and ensure that the patient is assessed by senior medical staff).

• If these patients have co-existing COPD or other risk factors for hypercapnic respiratory failure, aim at a saturation of 88-92% pending blood gas results but adjust to 94-98% if the PaCO2 is normal (unless there is a history of previous hypercapnic respiratory failure requiring NIV or IPPV) and recheck blood gases after 30-60 min.

Additional comments Grade of

recommendation

Acute hypoxaemia (cause not yet diagnosed)

Reservoir mask at 10-15 l/min if initial SpO2

<85%, otherwise nasal cannulae or simple face mask

Grade D

Patients requiring reservoir mask therapy need urgent clinical assessment by senior staff

Acute asthma Grade C

Pneumonia Grade C

Lung cancer Grade C

Postoperative breathlessness Management depends on underlying cause Grade D

Acute heart failure Consider CPAP or NIV in cases of pulmonary oedema

Grade D

Pulmonary embolism Most patients with minor pulmonary embolism are not hypoxaemic and do not require oxygen therapy

Grade D

Pleural effusions Most patients with pleural effusions are not hypoxaemic. If hypoxaemic, treat by draining the effusion as well as giving oxygen therapy

Grade D

Pneumothorax Needs aspiration or drainage if the patient is hypoxaemic. Most patients with pneumothorax are not hypoxaemic and do not require oxygen therapy

Grades C and D

Use a reservoir mask at 10-15 l/min if admitted for observation. Aim at 100% saturation (oxygen accelerates clearance of pneumothorax if drainage is not required)

Deterioration of lung fibrosis or other interstitial lung disease

Reservoir mask at 10-15 l/min if initial Sp02 <85%, otherwise nasal cannulae or simple face mask.

Grade D

Severe anaemia The main issue is to correct the anaemia. Most anaemic patients do not require oxygen therapy

Grades B and D

Sickle cell crisis Requires oxygen only if hypoxaemic (below the above target ranges or below what is known to be normal for the individual patient) Low oxygen tension will aggravate sickling

Grade B

COPD, chronic obstructive pulmonary disease; CPAP, continuous positive airway pressure; IPPV, intermittent positive pressure ventilation; NIV, non-invasive ventilation; PaCO2, arterial carbon dioxide tension; SpO2, arterial oxygen saturation measured by pulse oximetry.

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APPENDIX C Referenced from the British Thoracic Society

COPD and other conditions requiring controlled or low-dose oxygen therapy

• Prior to availability of blood gases, use a 28% Venturi mask at 4 l/min and aim for an oxygen saturation of 88-92% for patients with risk factors for hypercapnia but no prior history of respiratory acidosis. (Grade D)

• Adjust target range to 94-98% if the PaC02 is normal (unless there is a history of previous NIV or IPPV) and recheck blood gases after 30-60min (Grade D)

• Aim at a prespecified saturation range (from alert card) in patients with a history of previous respiratory acidosis. These patients may have their own Venturi mask. In the absence of an oxygen alert card but with a history of previous respiratory failure (use of NIV or IPPV), treatment should be commenced using a 28% oxygen mask at 4 l/min in prehospital care or a 24% Venturi mask at 2-4 l/min in hospital settings with an initial target saturation of 88-92% pending urgent blood gas results. (Grade D)

• If the saturation remains below 88% in prehospital care despite a 28% Venturi mask, change to nasal cannulae at 2-6 l/min or a simple mask at 5 l/min with target saturation of 88-92%. All at-risk patients with alert cards, previous NIV or IPPV or with saturation <88% in the ambulance should be treated as a high priority. Alert the A&E department that the patient requires immediate senior assessment on arrival at the hospital. (Grade D)

• If the diagnosis is unknown, patients aged >50 years who are long-term smokers with a history of chronic breathlessness on minor exertion such as walking on level ground and no other known cause of breathlessness should be treated as if having COPD for the purposes of this guideline. Patients with COPD may also use terms such as chronic bronchitis and emphysema to describe their condition but may sometimes mistakenly use “asthma”, FEV, should be measured on arrival in hospital if possible and should be measured at least once before discharge from hospital in all cases of suspected COPD. (Grade D)

• Patients with a significant likelihood of severed COPD or other illness that may cause hypercapnic respiratory failure should be triaged as very urgent and blood gases should be measured on arrival in hospital. (Grade D)

• Blood gases should be rechecked after 30-60 min (of if there is clinical deterioration) even if the initial PaCO2 measurement was normal. (Grade D)

• If the PaCO2 is raised but pH is ≥7.35 ([H+] ≤ nmol/l), the patient has probably got long-standing

hypercapnia; maintain target range of 88-92% for these patients. Blood gases should be repeated at 30-60 min to check for rising PaC02 or falling pH. (Grade D)

• If the patient is hypercapnic (PaC02>6 kPa or 45 mm Hg) and acidotic (pH<7.35 or [H+] >45 nmol/l)

consider non-invasive ventilation, especially if acidosis has persisted for more than 30 min despite appropriate therapy. (Grade A)

Additional comments Grade of

recommendation

COPD May need lower range if acidotic or if known to be very sensitive to oxygen therapy. Ideally use alert cards to guide treatment based on previous blood gas results. Increase flow by 50% if respiratory rate is >30 (see recommendation 32)

Grade C

Exacerbation of CF Admit to regional CF centre if possible; if not, discuss with regional centre or manage according to protocol agreed with regional CF centre.

Grade D

Ideally use alert cards to guide therapy. Increase flow by 50% if respiratory rate is >30 (see recommendation 32)

Chronic neuromuscular disorders May require ventilatory support. Risk of hypercapnic respiratory failure

Grade D

Chest wall disorders For acute neuromuscular disorders and subacute conditions such as Guillain-Barre syndrome (see table 4)

Grade D

Morbid obesity Grade D

CF, cystic fibrosis; COPD, chronic obstructive pulmonary disease; CPAP, continuous positive airway pressure; IPPV, intermittent positive pressure ventilation; NIV, non-invasive ventilation; PaCO2, arterial carbon dioxide tension; Sp02 , arterial oxygen saturation measured by pulse oximetry.

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APPENDIX D Referenced form the British Thoracic Society

Conditions for which patients should be monitored closely but oxygen therapy is not required unless the patient is hypoxaemic

• If hypoxaemic, the initial oxygen therapy is nasal cannulae at 2-6 l/min or simple face mask at 5-10 l/min unless saturation is <85% (use reservoir mask) or if at risk from hypercapnia (see below).

• The recommended initial target saturation range, unless stated otherwise, is 94-98%.

• If oximetry is not available, give oxygen as above until oximetry or blood gas results are available.

• If patients have COPD or other risk factors for hypercapnic respiratory failure, aim at a saturation of 88-92% pending blood gas results but adjust to 94-98% if the PaC02 is normal (unless there is a history of respiratory failure requiring NIV or IPPV) and recheck blood gases after 30-60 min.

Additional comments Grade of

recommendation

Myocardial infarction and acute coronary syndromes

Most patients with acute coronary artery syndromes are not hypoxaemic and the benefits / harms of oxygen therapy are unknown in such cases

Grade D

Stroke Most stroke patients are not hypoxaemic. Oxygen therapy may be harmful for non-hypoxaemic patients with mild to moderate strokes.

Grade B

Pregnancy and obstetric emergencies

Oxygen therapy may be harmful to the fetus if the mother is not hypoxaemic (see recommendations 14-17)

Grades A-D

Hyperventilation or dysfunctional breathing

Exclude organic illness. Patients with pure hyperventilation due to anxiety or panic attacks are unlikely to require oxygen therapy

Grade C

Rebreathing from a paper bag may cause hypoxaemia and is not recommended.

Most poisonings and drug overdoses (see table 1 for carbon monoxide poisoning)

Hypoxaemia is more likely with respiratory depressant drugs, give antidote if available (e.g., naloxone for opiate poisoning)

Grade D

Check blood gases to exclude hypercapnia if a respiratory depressant drug has been taken. Avoid high blood oxygen levels in cases of acid aspiration as there is theoretical evidence that oxygen may be harmful in this condition.

Monitor all potentially serious cases of poisoning in a level 2 or level 3 environment (high dependency unit or ICU)

Poisoning with paraquat or bleomycin

Patients with paraquat poisoning or bleomycin lung injury may be harmed by supplemental oxygen.

Grade C

Avoid oxygen unless the patient is hypoxaemic

Target saturation is 88-92%

Metabolic and renal disorders Most do not need oxygen (tachypnoea may be due to acidosis in these patients)

Grade D

Acute and subacute neurological and muscular conditions producing muscle weakness

These patients may require ventilatory support and they need careful monitoring which includes spirometry. If the patient’s oxygen level falls below the target saturation, they need urgent blood gas measurements and are likely to need ventilatory support.

Grade C

COPD, chronic obstructive pulmonary disease; ICU, intensive care unit; IPPV, intermittent positive pressure ventilation; NIV, non-invasive ventilation; PaC02, arterial carbon dioxide tension; Sp02, arterial oxygen saturation measured by pulse oximetry.

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APPENDIX E Referenced form the British Thoracic Society

Oxygen prescription for acutely hypoxaemic patients in hospital

Any increase in Fio2 must be followed by repeat ABGs in 1 h (or sooner if conscious level deteriorates)

*if pH is<7.35 ([H+]>45 nmol/l) with normal or low pC02, investigate and treat for metabolic acidosis and keep Sp02 94-98%

**Patients previously requiring NIV or IPPV should have a target range of 88-92%, even if the initial Paco2 is normal.

Chart 1: Oxygen prescription for acutely hypoxemic patients in hospital. ABG, arterial blood gas; COPD, chronic obstructive pulmonary disease; Fio2, fraction of inspired oxygen; ICU, intensive care unit; NIV, non-invasive ventilation; Pco2, carbon dioxide tension; Sp02, arterial oxygen saturation measured by pulse oximetry.

Is the patient critically ill or in a peri-arrest condition?

Commence treatment with reservoir mask or bag-valve mask and manage as advised in table 1

Is this patient at risk of hypercapnic respiratory failure (type 2 respiratory failure)? The main risk factor is severe or moderate COPD (especially with previous respiratory failure or on long-

term oxygen) Other patients at risk include people with severe chest wall or spinal disease (e.g. kyphoscoliosis),

neuromuscular disease, severe obesity, cystic fibrosis, bronchiectasis or previously unrecognised COPD Narcotic/sedative overdose not covered by this algorithm (see table 4 and section 8.13.5)

Yes

No

Yes Target saturation is 88-92% or level on alert

card whilst awaiting blood gas results

No Aim for Sp02 94-98%

Start 28% or 24% O2 and obtain ABGs (reduce Fio2 if Sp02>92% or above range

stated on alert card)

Sp02<94% on air or oxygen or if requiring oxygen to achieve above targets

Yes →Commence oxygen, as per tables 2 or 4 and check ABG

No pH<7.35* or [H

+]>45 nmol/l*

and pC02>6.0 kPa (Respiratory acidosis

or patient tiring)

pH≥7.35 or [H+] ≤ 45

nmol/l and pC022>6kPa (Hypercapnia)

pC02≤6.0 kPa (normal or low)

pC02 ≥6.0 kPa Or respiratory

deterioration (see box in chart 2)

Monitor Sp02 Oxygen not required unless saturation falls below target range

Seek immediate senior review

Consider NIV or invasive ventilation

Treat with the lowest dose

Venturi mask that will keep

Sp02between 88-

Seek immediate senior review

Consider invasive ventilation

Treat with lowest Fio2 to keep Sp02

88-92% via Venturi mask pending senior

medical advice or NIV or ICU admission

Repeat ABGs at 30-60 min: If respiratory acidosis

(pH<7.35 or [H+]>45nmol/l and

pC02>6.0) Seek immediate senior review,

consider NIV/ICU.

Consider reducing Fio2 if pC02≥8.0kPa

Treat appropriately aiming to keep Sp02 between 94% and

98%**

Repeat ABG in 30-60 min for all patients at

risk of type 2 respiratory failure

Treat urgently. Aim for Sp02 94-98% pending senior review. Also consider COPD or other undiagnosed chronic hypercapnic respiratory failure.

If likely aim for Sp02 of 88-92%

Treat appropriately aiming to keep Sp02 94-98%

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APPENDIX F Local Oxygen Prescription Chart

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APPENDIX G Alert cards for patients known to have previous respiratory acidosis

(These along with the appropriate venturi mask will be issued to patients who are discharged following an admission with respiratory acidosis following review by a respiratory consultant physician)

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APPENDIX H ADMINISTERING ACUTE OXYGEN THERAPY

ACTION RATIONALE

1. Ensure patency of airway. To promote effective oxygenation.

2. The type of delivery system used will depend on the needs and comfort of the patient. It is the nurse’s / physiotherapist’s role to assess the patient and use the prescribed system.

To provide accurate oxygen delivery to the patient. Most stable patients prefer nasal cannulae to masks.

3. Ensure oxygen is prescribed on prescription chart. In some situations a patient group directive may be in place to allow designated nurses / physiotherapists to administer oxygen. In these cases the doctor must review the patient’s condition within the stated time and prescribe oxygen accordingly.

To ensure a complete record is maintained and expedite patient treatment. The exception to this action would be during an emergency situation where the resuscitation guideline should be followed.

4. Ensure that the oxygen dose is clearly indicated. If nasal cannula or reservoir masks are being used check that the flow rate is clearly indicated.

In accordance with the administration of medicines policy.

5. Inform patient and or relative / carer of the combustibility of oxygen.

Oxygen supports combustion therefore there is always a danger of fire when oxygen is being used.

6. Show and explain the oxygen delivery system to the patient. Give the patient the information sheet about oxygen.

To obtain consent and co-operation.

7. Assemble the oxygen delivery system carefully as shown in Appendix H.

To ensure oxygen is given as prescribed.

8. Attach oxygen delivery system to oxygen source.

To ensure oxygen supply is ready.

9. Attach oxygen delivery system to patient according to manufacturers instructions.

For oxygen to be administered to patient.

10. Turn on oxygen flow in accordance with prescription and manufacturers instruction.

To administer correct % of oxygen.

11. Ensure patient has either a drink or a mouthwash within reach.

To prevent drying or the oral mucosa.

12. Clean oxygen mask as required with general purpose detergent and dry thoroughly needed. Discard systems after use.

To minimise risk of infection. (Single patient device)

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APPENDIX I

EQUIPMENT USED IN THE DELIVERY OF OXYGEN (Choose the appropriate delivery device)

1. Oxygen source (piped or cylinder) 2. Flow meter 3. Saturation monitor 4. Oxygen Delivery system - (see Appendix J for advice on use of each device);

a) Nasal cannula

DEVICE DESCRIPTION PURPOSE

Nasal Cannulae

Nasal cannulae consist of pair of tubes about 2cm long, each projecting into the nostril and stemming from a tube which passes over the ears and which is thus self-retaining.

Uncontrolled oxygen therapy

Cannulae are preferred to masks by most patients. They have the advantage of not interfering with feeding and are not as inconvenient as masks during coughing and sneezing.

It is not advisable to assume what percent oxygen (FI02) the patient is receiving according to the Litres delivered but this is not important if the patient is in the correct target range.

ACTION RATIONALE

1. (When using nasal cannula).

Position the tips of the cannula in the patient’s nose so that the tips do not extend more than 1.5cm into the nose.

Overlong tubing is uncomfortable, which may make the patient reject the procedure. Sore nasal mucosa can result from pressure or friction of tubing that is too long.

2. Place tubing over the ears and under the chin as shown above. Educate patient re prevention

To allow optimum comfort for the patient.

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of pressure areas on the back of the ear. To prevent pressure sores.

3. Adjust flow rate, usually 2-4 l/min but may vary from 1-6 l/min in some circumstances.

Set the flow rate to achieve the desired target oxygen saturation.

b) Fixed performance mask (Venturi mask and valve)

DEVICE DESCRIPTION PURPOSE

Venturi mask

A mask incorporating a device to enable a fixed concentration of oxygen to be delivered independent of patient factors or fit to the face or flow rate. Oxygen is forced out through a small hole causing a Venturi effect which enables air to mix with oxygen.

Controlled oxygen therapy

This is a high performance oxygen mask designed to deliver a specified oxygen concentration regardless of breathing rate or tidal volume.

Venturi devices come in different colours for %

Blue = 24%

White = 28%

Yellow = 35%

Red = 40%

Green = 60%

ACTION RATIONALE

1. (When using Venturi mask)

Connect the mask to the appropriate Venturi barrel attached firmly into the mask inlet.

To ensure that patient receives the correct concentration of oxygen

2.Fasten oxygen tubing securely. Correctly secured tubing is comfortable and prevents displacement of mask/cannulae.

3.Assess the patient’s condition and functioning of equipment at regular intervals according to care plan.

To ensure patient’s safety and that oxygen is being administered as prescribed.

4. Adjust flow rate. The minimum flow rate is indicated on the mask or packet. The flow should be doubled if the patient has a respiratory rate above 30 per minute.

Higher flows are required for patients with rapid respiration and high inspiratory flow rates. This does not affect the concentration of oxygen but allows the gas flow rate to match the patient’s breathing pattern.

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c) Simple face mask (variable flow)

DEVICE

DESCRIPTION

Mask has a soft plastic face piece, vent holes are provided to allow air to escape.

Maximum 50%-60% at 15ltrs/minute flow.

PURPOSE

This is a variable performance device. The oxygen concentration delivered will be influenced by:

a. the oxygen flow rate( litres per minute) used, leakage between the mask and face;

Simple face mask

Variable Percentage

(Delivers unpredictable concentrations that vary with flow rate)

Nasal cannulae should be used for most patients who require medium dose oxygen but a simple face mask may be used due to patient preference or if the nose is blocked

Uncontrolled Oxygen therapy

b. the patient’s tidal volume and breathing rate.

NOT to be used for CO2 retaining patients.

ACTION RATIONALE

(If using simple face mask) Gently place mask over the patient’s face, position the strap behind the head or the loops over the ears then carefully pull both ends through the front of the mask until secure.

Ensure a comfortable fit and delivery of prescribed oxygen is maintained.

Check that strap is not across ears and if necessary insert padding between the strap and head.

Adjust the oxygen flow rate. Must never be below 5L/min

To prevent irritation.

Flows below 5L/m do not give enough oxygen

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d) Reservoir mask (non re-breathe mask)

DEVICE DESCRIPTION PURPOSE

Reservoir Mask

(Non-rebreathe Mask)

Mask has a soft plastic face piece with flap-valve exhalation ports which may be removed for emergency air-intake. There is also a one-way valve between the face mask and reservoir bag.

Uncontrolled oxygen therapy

In non re-breathing systems the oxygen may be stored in the reservoir bag during exhalation by means of a one-way valve. High concentrations of oxygen 80-90% can be achieved at relatively low flow rates.

NOT to be used for C02 retaining patients except in life-threatening emergencies such as cardiac arrest or major trauma.

ACTION RATIONALE

1. (Non Rebreathe Reservoir Mask)

Ensure the reservoir bag is inflated before placing mask on patient, this can be maintained by using 10-15 litres of oxygen per min.

To ensure the optimal flow of oxygen to the patient.

2. Adjust the oxygen flow to the prescribed rate.

Inadequate flow rates may result in administration of inadequate oxygen concentration to the patient.

In disposable reservoir, oxygen flows directly into the mask during inspiration and into the reservoir bag during exhalation. All exhaled air is vented through a port in the mask and a one-way valve between the bag and mask, which prevents re-breathing.

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e) Tracheostomy mask for patients with tracheostomy or laryngectomy

DEVICE

DESCRIPTION

Mask designed for “neck breathing patients”. Fits comfortably over tracheostomy or tracheotomy. Exhalation port on front of mask.

PURPOSE

This is a variable performance device for patients with tracheostomy or tracheotomy. The oxygen concentration delivered will be influenced by:

a. the oxygen flow rate(

litres per minute) used.

b. the patient’s tidal volume and breathing rate.

Tracheostomy mask

Variable Percentage

(Delivers unpredictable concentrations that vary with flow rate)

Uncontrolled Oxygen therapy

Use cautiously at low flow rates in CO2 retaining patients as there may be no alternative.

ACTION RATIONALE Gently place mask over the patient’s airway,

position the strap behind the head then carefully pull both ends through the front of the mask until secure.

Ensure a comfortable fit and delivery of prescribed oxygen is maintained.

Adjust the oxygen flow rate to

achieve the desired target

saturation range. Start at 4 l/min

and adjust the flow up or down

as necessary to achieve the desired

oxygen saturation range.

To ensure that the correct amount of oxygen is given to keep the patient in the target range.

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f) Oxygen Flow Meter

DEVICE

DESCRIPTION

Device to allow the patient to receive an accurate flow of oxygen, usually between 2 and 15 litres per minute.

May be wall-mounted or on a cylinder.

Take special care if your Trust uses a twin oxygen outlets or if there are air outlets which may be mistaken for oxygen outlets.

PURPOSE

To ensure that the patient receives the correct amount of oxygen.

3

2

1

3

2

1

Correct Setting for 2 l/min

Oxygen flow meter

Delivers oxygen to the patient.

ACTION RATIONALE

Attach the oxygen tubing to the

nozzle on the flow meter.

Turn the finger-valve to obtain the desired flow rate. The CENTRE of the ball shows the correct flow rate. The diagrams shows the correct setting to deliver 2 l/min.

To ensure that the patient receives the correct amount of oxygen.

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APPENDIX J

PERSONNEL WHO MAY ADMINISTER OXYGEN

Any qualified nurse, doctor, RSCN, RN or physiotherapist, in accordance with policy for administration of medicines.

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APPENIDX K Referenced form the British Thoracic Society

Flow chart for oxygen administration See patient’s drug chart and chart 1 and tables 1-4 for starting dose and target saturation. Choose the most suitable delivery system and flow rate. Titrate oxygen up or down to maintain the target oxygen saturation. The table below shows available options for stepping dosage up or down. The chart down not imply any equivalence of dose between Venturi masks and nasal cannulae. Allow at least 15 minutes at each dose before adjusting further upwards or downwards (except with major and sudden fall in saturation). Once your patient has adequate and stable saturation on minimal oxygen dose, consider discontinuation of oxygen therapy.

Venturi 24% 2-4 l/min* Nasal cannulae 1 l/min

Blue

White

Yellow

Venturi 28% 4-6 l/min

Venturi 35% 8-10 l/min

Venturi 40% 10-12 l/min

Or simple face mask at 5-6 l/min

Red

Venturi 60% 12-15 l/min

Or simple face mask at 7-10 l/min

Reservoir mask at 15 l/min oxygen flow

All acutely ill patients should be given 100% oxygen whilst awaiting immediate medical review

*For Venturi masks, the higher flow rate is required if the respiratory rate is >30

Patients in a per-arrest situation and critically ill patients should be given maximal oxygen therapy via reservoir mask or bag-valve mask whilst immediate medical help is arriving (except for patients with COPD with known oxygen sensitivity recorded in patient’s case notes and drug chart or in the EPR: keep saturation at 88-92% for this subgroup of patients)

Seek medical advice if patient appears to need increasing oxygen therapy or if there is a rising mEWS or Track and Trigger score

All patients must have ABG or earlobe blood gases (ELBG) within 1 h of requiring increased oxygen dose.

Signs of respiratory deterioration

• ↑respiratory rate (especially if <30)

• ↓Spo2

• ↑oxygen dose needed to keep Spo2 in target range

• ↑EWS/trigger score

• CO2 retention

• Drowsiness

• Headache

• Flushed face

• Tremor

Seek medical advice

Flow chart for oxygen administration on general wards in hospitals. ABG, arterial blood gas; EPR, electronic patient record, EWS, Early Warning Score; Sp02 arterial oxygen saturation measured by pulse oximetry.

Nasal cannulae 2 l/min

Nasal cannulae 4 l/min

Green

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APPENDIX L Early Warning Observation Score Charts

A physiological track and trigger system has been adopted at South Tees NHS Trusts. The Early Warning Score System (EWSS) is a valuable tool to assist in the recognition of abnormal physiological observations which together with a graded response strategy can help to avert deterioration of acutely ill patients by seeking appropriate assistance.

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Appendix L (continued)

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APPENDIX M

The EWS score is a multi parameter aggregate weighted scoring system that also includes an explicit response required from a single parameter trigger of oxygen saturation.

The oxygen saturation triggers are as follows: Medium score

• SpO2 < 90 on air < 94 on 15 l O2 (unless documented as acceptable for patient by Consultant) Patient causing concern (e.g. increasing O2 requirements*)

High score

• SpO2 < 85 on air < 90 on 15 l O2

* if oxygen sats fall by 3% or more or increased oxygen is required to maintain the saturations in the target range this should prompt clinical review and in most cases blood gases.

Graded Response Chart

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APPENDIX N Codes for recording oxygen delivery on EWS chart

A Air

AX Measurement on air for a patient on PRN oxygen

AW Measurement on air for a patient being weaned off oxygen but not yet discontinued on chart

N Nasal cannulae

SM Simple mask

V24 Venturi 24%

V28 Venturi 28%

V35 Venturi 35%

V40 Venturi 40%

V60 Venturi 60%

H28 Humidified oxygen at 28% (also H35, H40, H60)

RM Reservoir mask

TM Tracheostomy mask

CP Tracheostomy mask

NIV Patient on NIV

OTH Other device

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APPENDIX O

HUMIDIFICATION

This should only be used if specifically requested by the doctor or physiotherapist in the following circumstances.

1. If the flow rate exceeds 4 litres per minute for several days 2. Tracheotomy or tracheostomy patients (“neck-breathing patients)” 3. Cystic Fibrosis patients 4. Bronchiectasis patients 5. Patients with a chest infection retaining secretions

Can be given by warm or cold humidifier systems (warm humidifier systems are mainly used in critical care areas)

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APPENDIX P

HEALTH AND SAFETY

1. Inform patients and carers about the combustibility of oxygen

Oxygen supports combustion, there is always a danger of fire when oxygen is being used.

2. Oxygen should be stored in an area designated as no smoking.

3. Electrical appliances should be kept at least five feet away from the source of oxygen.

Oxygen can be potentially dangerous when in contact with sources of ignition and flammable material.

4. Avoid grease or oil coming into contact with apparatus.

5. Store unused cylinders in a dry well ventilated place.