T wo scientists were honored with the Komen Foundation’sBrinker Award for Scientific Distinction at the 26th Annual

San Antonio Breast Cancer Symposium in early December.Established by the Foundation in 1992, the award recognizesleading scientists for significant work that advances basicresearch concepts or clinical applications in the fields of breastcancer research, screening or treatment.

The 2003 Clinical Research Award was awarded to Walter C.Willett, M.D., Dr. P.H., professor of epidemiology andnutrition and chairman of the department of nutrition atHarvard’s School of Public Health and professor of medicine atHarvard Medical School. The 2003 Basic Science Award wasawarded to Mina J. Bissell, Ph.D., distinguished scientist, lifesciences division, Lawrence Berkeley National Laboratory.

Each recipient received a $10,000 cash prize and a crystalstatuette from Tiffany & Co. The award began from apartnership between the Komen Foundation and BrinkerInternational, one of the world’s premier multi-operatorrestaurant companies.

Walter C. Willett, M.D., Dr. P.H., studied food scienceat Michigan State Universityand graduated from theUniversity of MichiganMedical School beforeobtaining a doctorate in publichealth from Harvard Schoolof Public Health.

Dr. Willett has focused muchof his work over the last 25years on the development ofmethods, using bothquestionnaires andbiochemical approaches, tostudy the effects of diet on theoccurrence of major diseases.He first applied these methodsin 1980 in the Nurses’ HealthStudy I, a cohort of more than121,000 female registerednurses 30-55 years of age. The

frontlineThe Susan G. Komen Breast Cancer Foundation’s Newsletter Fourth Quarter 2003

Collaboration is Key 2Letrozole Study Results 3Breast Cancer 3-Day Schedule 3Breast Cancer: The Year in Review 4Highlights from the 2003 San Antonio

Breast Cancer Symposium 5Figures Underscore Importance

of Early Detection 6Educational Materials 6Our Researchers 7Lee National Denim Day® 8Capitol Hill Update 8Partners in the Promise 9Helpline Volunteers 11Komen Affiliate News 12Komen Race for the Cure® Series 14Johnson & Johnson

Making a Difference Together 14Marketplace 15Your Donation Can Help 15ActNowEndBreastCancer.org 16

i n s i d e

Scientists Honored with Komen Foundation’sBrinker Award for Scientific Distinction

nurses completed biannual mailed questionnaires about known orsuspected risks for cancer and cardiovascular disease. Dr. Willettis also principal investigator of the Nurses’ Health Study II, aprospective cohort investigation established in 1989 with morethan 116,000 younger female registered nurses. This study is alsodesigned to examine the association between lifestyle andnutritional factors and the occurrence of breast cancer and othermajor illnesses.

In addition to his work with the Nurses’ Health Studies I and II,in 1996 Dr. Willett initiated a parallel prospective study of dietin relation to cancer and cardiovascular disease among 52,000men called the Health Professionals Follow-up Study. He haspublished more than 800 articles, primarily on lifestyle riskfactors for heart disease and cancer, and wrote the textbook,Nutritional Epidemiology, 2nd Edition, published by OxfordUniversity Press. His recent book for the general public, Eat,Drink and Be Healthy: The Harvard Medical School Guide to HealthyEating, has appeared on most major best seller lists.

Mina J. Bissell, Ph.D., is a recognized leader in the field ofcell and molecular biology. Dr. Bissell studies the environmentthat surrounds breast cells in order to better understand breastcancer. Because most tissues share the same genetic information,the question of why some tissues get cancer while others don’tis a central question in her research.

She earned an A.B. with honors in chemistry fromRadcliffe/Harvard College and a Ph.D. in bacterial genetics fromHarvard University in 1969. She was a Milton Fellow at Harvardand an American Cancer Society Fellow in the department ofmolecular biology at the University of California-Berkeley.

(continued on page 7)

Walter C. Willett, M.D., Dr. P.H. Mina J. Bissell, Ph.D.

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Collaboration is Key in Fighting Breast CancerBy Susan Braun, Komen Foundation President and Chief Executive Officer

Numerous Komen Affiliates throughout the United States fundHadassah’s Check It Out program at local high schools andcolleges. The program encourages young women to get into thehabit of performing monthly breast self-examinations so theycan take responsibility for keeping themselves well. Thestudents are also asked to take the information home and shareit with family members so they too can practice healthylifestyles. Check it Out programs are funded by KomenAffiliates in Columbus, Ohio; Atlanta, GA; Scranton, PA;Pittsburgh, PA; Sacramento, CA; and St. Louis, MO.

Y-ME: Y-ME National Breast Cancer Organization wasfounded in 1978 by two breast cancer patients, Ann Marcouand the late Mimi Kaplan. The mission of Y-ME is to ensure,through information, empowerment and peer support, that noone faces breast cancer alone.

There are 10 local Y-ME chapters in the United States, eachechoing the mission and values of Y-ME in their role as a breasthealth and breast cancer resource in their communities. TheKomen Foundation — through its Affiliate Network —provides funding for several of Y-ME’s programs and servicesat the local level. For example, the Komen Chatanooga Affiliatefunds two Y-ME programs in Tennessee, including, Uniting forBreast Cancer Awareness, a program that works to improve breastcancer awareness and increase the frequency of breast self-examination and screenings among minority women over theage of 35. A second program, called the Healing Arts TherapyProgram, offers women an alternative support group throughpainting, music and creative writing.

YWCA: The mission of the YWCA is to empower women and girlsand to eliminate racism. The YWCA offers a wide range of servicesand programs, including the highly successful ENCOREplus®

program, a system of health promotion through education, clinicalservice delivery and patient navigation and advocacy.

Using funding provided by Komen Affiliates throughout thecountry, this community-based program aids women in need ofearly detection education and breast and cervical cancerscreening and support services. It also provides women undertreatment and recovering from breast cancer with a unique,combined peer group support and exercise program. It’s designedto eliminate inequalities in health care experienced by manywomen by removing barriers to access and promoting effectivecommunity-based outreach, education, referral to clinical servicesand support systems.

Each ENCOREplus®program is customized for the population

and area it serves. Komen Affiliates fund some variation of theprogram in more than 40 communities across the U.S. �

A s one of the nation’s largest private fundersof breast cancer education and outreach

programs, the Komen Foundation is honoredto partner with a number of highly respectednonprofit organizations and agencies. Together,we are true partners in the fight to eliminatebreast cancer. By providing these organizations

with funding, the Komen Foundation enables them to offermuch-needed programs and services — such as mammographyscreening, education, support and treatment — that mightotherwise not exist.

Below is just a sampling of some of the groups we collaboratewith. We are proud of the life-saving work they are doing intheir communities.

The Rose: Founded in 1986 in Houston, Texas, by DorothyWeston-Gibbons and Dixie Melillo, M.D., the mission of TheRose is to reduce deaths from breast cancer by providingscreening, diagnosis and access to treatment for womenregardless of their ability to pay.

Since its beginnings, The Rose has depended upon communitysupport from organizations like the Komen Foundation to fulfillits mission. This year, more than 30,000 women will receiveservices at The Rose (at one of two community-based sites inHouston). Services include mammography screening,diagnostics, ultrasounds, breast biopsies, bone density testing,support services, education and access to treatment.

An estimated 5,000 women will receive these services at nocharge through EMPOWER HER, The Rose Sponsorship Programfor Low-Income Uninsured Women. The program, which is fundedlargely by a grant from the Komen Houston Affiliate, providesbreast cancer detection services to those who cannot afford thecosts of these potentially life-saving procedures by addressingthe financial, cultural, language and literacy barriers low-income uninsured women often face.

Hadassah: Hadassah, the Women’s Zionist Organization ofAmerica, was founded in 1912 by Henrietta Szold, a Jewishscholar and activist. As one of the largest volunteer organizationsand the largest women’s organizations in the U.S., Hadassahsponsors a variety of education and health awareness programsand is an advocate for issues of importance to women and tothe American Jewish community.

Hadassah is dedicated to a breast health initiative that works toeducate persons of all ages. One of the initiative’s primaryfocuses, however, is Check it Out, a free program designed toeducate young women about breast cancer, its warning signsand proper breast care practices that can lead to earlydetection. Target audiences are located at high schools,churches, synagogues and service organizations.

Susan Braun

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D ata from a Canadian-led international clinical trial indicatethat post-menopausal breast cancer survivors with

estrogen receptor-positive forms of early breast cancer whotook the drug letrozole after completing an initial five years oftamoxifen therapy significantly reduced their risk of cancerrecurrence compared to women taking a placebo. The studyresults appeared in the October 9 online edition of the NewEngland Journal of Medicine (NEJM).

The five-year double-blind study, which involved 5,187 womenin the United States, Canada and Europe, was stopped,according to protocol, because data indicated that the womenin the placebo arm of the study should begin benefiting fromthe use of letrozole as soon as possible.

Overall, letrozole reduced the risk of recurrence by 43 percent.After four years of participating in the trial, 13 percent of thewomen on the placebo, but only seven percent of those onletrozole, had a recurrence. This corresponds to an absolutedifference of six percent. Deaths from breast cancer were alsoreduced. Seventeen women taking the placebo died of breastcancer compared to nine taking letrozole; however, thisdifference was not statistically significant.

“Letrozole offers new promise for thousands of breast cancerpatients,” said Cheryl Perkins, M.D., senior clinical advisor forthe Komen Foundation. “As a breast cancer survivor, I knowfirst-hand the anxiety a patient experiences when she finishesher treatment. The fear of recurrence is something that’s always

Letrozole Study Results Show SignificantReduction in Breast Cancer Recurrence

with you. Letrozole may afford added peace of mind to thosewomen who are appropriate candidates for this treatment andelect to use it under a physician’s care.”

The recommended course of tamoxifen treatment for breastcancer patients is five years, after which time the drug stopsbeing effective because some tumors become resistant to it.Letrozole works via a different biological mechanism thantamoxifen, which blocks the hormone estrogen. Letrozole andother aromatase inhibitors suppress the production of estrogenby the adrenal gland. Estrogen is thought to stimulate thedevelopment and growth of breast cancer.

According to study organizers, approximately 80,000 to 100,000women in the United States alone are potential candidates forletrozole treatment. While the encouraging news about letrozolecould alter current practices in cancer treatment, not all patientsare candidates to take the drug, and questions about the drug’slong-term side effects and efficacy remain unanswered.

“While letrozole may represent an extension of the time todisease recurrence, additional study is needed to determine thelong-term side effects, such as osteoporosis, that may resultfrom estrogen depletion caused by the drug,” Dr. Perkins said.“In addition, more follow-up time is needed to determinewhether there may be increased risk of cardiovascular events.Other important questions, such as the benefit to women whohave been without tamoxifen treatment for more than threemonths, remain unanswered.” �

2004 Breast Cancer 3-Day Schedule

The Komen Foundation has joined forces with the NationalPhilanthropic Trust (NPT), an independent non-profit

organization, for the Breast Cancer 3-Day. These life-changingevents provide yet another way for individuals to work togetherwith their families and friends to make a meaningful differencein the fight against breast cancer.

During three awe-inspiring days, participants in Breast Cancer3-Day events cover 60 miles in this challenging butempowering experience.

The Komen Foundation receives 85 percent of the net proceedsfrom each event to support breast cancer research, education,screening and treatment. For more information visitwww.breastcancer3day.org. �

Boston, MAJuly 30-August 1

New York, NYAugust 6-8

Washington, D.C.August 13-15

Detroit, MIAugust 20-22 Chicago, IL

August 27-29 Minneapolis, MNSeptember 10-12

San Diego, CAOctober 1-3

Los Angeles, CAOctober 8-10

San Francisco, CAOctober 15-17

ArizonaOctober 22-24

A NATIONAL PHIA LANTHROPRR IC TRUST PROJET CT

B E N E F I T I N G

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Several breast health and breast cancer issues made headlinesin 2003, including breast self-examination, hormone

replacement therapy and lifestyle factors. What follows is a recapof the issues and the Komen Foundation’s recommendations.

The Headline: Breast Self-Examination (BSE)As a result of the Shanghai Study, the validity of BSE wascalled into question. This study occurred in Shanghai, China,from 1989-2000 and involved 266,000 women. Half had in-depth breast self-exam training and half received no training.After 10 years of follow-up, the researchers found that themortality from breast cancer was the same in both groups.

In May 2003, the American Cancer Society (ACS) updatedits guidelines for breast self-examination (BSE), recommendingthat BSE is an option for women beginning at age 20.

Komen Recommendation: The Komen Foundationcontinues to support BSE as part of a three-step approach tobreast health:• Monthly BSE starting by age 20. • Clinical breast examination by a healthcare provider at least

every three years starting at age 20 and annually after age 40.• Annual screening mammogram beginning at age 40. Women

under age 40 with either a family history of breast cancer orother concerns about personal risk should consult with ahealthcare provider about risk assessment and when tobegin mammography.

The Headline: Hormone Replacement TherapyResults from the Women’s Health Initiative (WHI) appearedin several reports. The WHI began evaluating the use ofhormone replacement therapy for disease prevention in post-menopausal women in 1997. It included 16,000 post-menopausal women ages 50-79 and was scheduled toconclude in 2005. One arm of the initiative ended prematurelyin 2002 because the women on combined hormonereplacement therapy (CHRT) — estrogen plus progestin —were noted to have an increase in the risk of heart disease andbreast cancer. Since this initial report, quality-of-life issueswere not found to be improved with CHRT use. There wasno increase in cognitive function in women 65 years and olderwho used CHRT. However, an increase in dementia wasreported. Short-term use was reported to be associated withmore abnormal mammograms, invasive tumors that werelarger at the time of diagnosis and at a later stage of diagnosisand an increase in the number of total and invasive breastcancers. A second arm of the study evaluating estrogen use inwomen who do not have a uterus is ongoing.

Komen Recommendation: Women are encouraged tobecome active participants with their healthcare providers intheir menopause and breast health care. Women shoulddiscuss these new findings and review the potential risks andbenefits with their healthcare provider when making decisionsabout the use of hormone therapy.

Breast Cancer: The Year in ReviewThe Headline: Lifestyle Factors and Breast Cancer RiskCorrelations between healthy lifestyles and risk of breastcancer appear to be modest at best. As studies are conductedand data mature, the picture will become clearer. Studiespublished this year addressed breast cancer risks associatedwith obesity, diet and exercise.

Obesity: The American Cancer Society Cancer Prevention StudyII looked at the influence of excess body weight on mortality fromall cancers, using body mass index (BMI), a measure of obesityusing one’s weight in kilograms divided by height in meterssquared. A BMI of 30 and over is considered obese. The studysuggested that 90,000 cancer deaths in the United States could beavoided each year if a lifetime BMI of 25 or less were maintained.According to the findings of this study, increased body weight andincreased death rates from all types of cancer — including breastcancer — were linked.

Diet: The Nurses’ Health Study II examined fat intake by pre-menopausal women 26-46 years of age in 1991. Findings revealedan association between animal fat, especially from red meat andhigh-fat dairy foods, and increased breast cancer risk. Pre-menopausal women who had the highest fat intake had a 33percent increased risk of invasive breast cancer.

Exercise: The Women’s Health Initiative was the source of moredata that resulted in a report in the Journal of the American MedicalAssociation in September 2003 (see page 8). The study of post-menopausal women ages 50-79 reported that increased physicalactivity was shown to reduce the risk of breast cancer by 18percent or more. Brisk walking for 1.25-2.5 hours per week wasenough to reduce the risk. Women with the lower BMI (less than24.1) had the greatest risk reduction. Risk was even reduced inwomen who were taking menopausal hormone therapy.

Komen Recommendation: The Komen Foundationencourages women to take charge of and become activeparticipants in their present and future health. That includesmanaging your diet, controlling your weight and engaging insome form of regular physical activity. �

Women’s Health Initiative, National Heart, Lung, and Blood Institute, National Institutes of Health, Department ofHealth and Human Services, http://www.nhlbi.nih.gov/whi/, updated June 2003.

Jennifer Hays, Ph.D., et al, Effects of Estrogen plus Progestin on Health-Related Quality of Life; The New EnglandJournal of Medicine, May 8, 2003, vol. 348, no. 19.

Stephen R. Rapp, Ph.D., et al, Effect of Estrogen Plus Progestin on Global Cognitive Function in PostmenopausalWomen, The Women’s Health Initiative Memory Study: A Randomized Controlled Trial; Journal of the AmericanMedical Association, May 28, 2003, vol. 289, no. 20, pp. 2663-2672.

Rowan T. Chlebowski, M.D., Ph.D., et al, Influence of Estrogen Plus Progestin on Breast Cancer and Mammographyin Healthy Postmenopausal Women; Journal of the American Medical Association, June 25, 2003; vol. 289, no. 24, pp. 3243-3253.

Eugenia E. Calle, Ph.D., Carmen Rodriguez, M.D., M.P.H., Kimberly Walter-Thurmond, B.A., and Michael H.Thun, M.D., The New England Journal of Medicine, vol. 348:1625-1638, April 24, 2003, no. 17.

Eunyoung Cho, et al., Premenopausal Fat Intake and Risk of Breast Cancer, Journal of the National Cancer Institute,vol. 95, no. 14, 1079-1085, July 16, 2003.

David B. Thomas, et al, Randomized Trial of Breast Self-Examination in Shanghai: Final Results, Journal of theNational Cancer Institute, vol. 94, no. 19, 1445-1457, October 2, 2002.

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The San Antonio Breast Cancer Symposium (SABCS) began in 1978 as a one-day event involving doctors from a

five-state area. By responding to the need for greater breastcancer education, the symposium has grown into a prominentinternational event recognized for disseminating the latestfindings in breast cancer research. The symposium remainsdedicated to addressing breast cancer concerns by providing a meaningful forum for the pursuit of the elimination of breast cancer. Below are a few of the highlights from the 2003 SABCS.

The Growing Data for Anastrozole (Arimidex®) in Early-Stage Breast Cancer A number of studies using anastrozole in the treatment of early stage breast cancer were highlighted at the 26th annualSABCS. Anastrozole belongs to a class of drugs known asaromatase inhibitors. It is used to treat both the early stagesand advanced stages of breast cancer in postmenopausalwomen with estrogen receptor-positive disease. Aromataseinhibitors work by cutting off the source of estrogen that thetumors need to survive by inhibiting the enzyme aromatase.Other aromatase inhibitors used in the treatment of breastcancer include letrozole and exemestane. For more informationabout the findings of the highlighted clinical trials involvinganastrozole, please visit www.komen.org.

Study Tests the Benefit of a Multi-Gene Assay in Breast Cancer The National Surgical Adjuvant Breast and Bowel Project(NSABP) announced that a unique breast cancer gene assaymay have potential in determining the likelihood of a womanwith breast cancer having a recurrence of the disease. Twostudies were presented using multi-gene assay technology. Geneassay technology works through the identification of geneswithin a tumor. A cancer’s behavior is determined by theexpression of thousands of genes. By identifying specific genesassociated with specific cancers, such as breast cancer, thisinformation can be used to predict a cancer’s behavior and theclinical consequence of such behavior.

In the NSABP B-20 and B-14 studies, the gene assay wastested in women who had received tamoxifen for the treatmentof estrogen receptor-positive, lymph node-negative breastcancer. In a smaller study reported by investigators from the M.D. Anderson Cancer Center, the assay was applied tonode-negative women. These women had not received adjuvanttamoxifen or chemotherapy. The studies quantified risk ofbreast cancer recurrence using a scoring method called a“Recurrence Score”. Once the score was determined, the

Highlights from the 2003 San Antonio Breast Cancer Symposium

patient was then categorized as having a low, intermediate orhigh risk for disease recurrence.

This new technology for determining risk of breast cancer andpredicting prognosis may one day exceed that of currentstandard measures. Standard measures currently include thepatient’s age, tumor size and tumor grade. Study results weremixed. Multi-gene assay did accurately predict recurrence riskfor women treated with tamoxifen but not for those women whohad not received adjuvant therapy. Although the results of thesestudies were mixed, this technology may be the first step in theability to accurately and precisely predict recurrence for womenwith breast cancer. In addition, it is the first time that suchtesting could be conducted using tumor tissue that is routinelyobtained and stored for patients.

Analysis of Adjuvant Therapy Trials ShowsInferior Outcome for African American Women Kathy Albain, M.D., of the Southwest Oncology Group(SWOG) of San Antonio, Texas, presented an analysis of theoutcomes of African Americans enrolled in SWOG adjuvanttherapy trials.

The outcome results from five clinical trials conducted by theSWOG in 6,676 women with early-stage breast cancer that had spread to the lymph nodes were combined and analyzed.Survival of African Americans was compared to that of all otherraces combined. Findings of the analysis showed that AfricanAmericans have worse survival even after taking into accountextent of disease at diagnosis, socioeconomic status anddifferences in treatment including access to care.

These findings suggest that further studies examiningdifferences in tumor characteristics at the molecular level for different races must be explored. The SWOG plans toinvestigate this possibility in future clinical trials of both breast and prostate cancer patients. �

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On October 2, 2003, the American Cancer Society (ACS)released its Breast Cancer Facts & Figures 2003-2004. The

analysis shows that advancements in cancer treatment and earlydetection are having a positive impact on the overall mortalityrate from breast cancer in the United States. More than 90percent of reported breast cancers are now being detected at alocalized or regional stage, for which five-year survival rates are97 percent and 79 percent, respectively.

The report, which is issued by ACS every two years, also containssobering news regarding the disparity in breast cancer mortalityrates between African American women and white women.

Report FindingsSpecifically, the report shows that while African Americanwomen and white women had approximately equal breast cancermortality rates in the 1980s, 30 percent more African Americanwomen than white women are now dying of breast cancer. Inaddition, African American women show a higher incidence ofbreast cancer among young women. Overall, African Americanwomen are more likely to present with tumors that are large (fivecentimeters or larger) and disease that has spread. Compared towhite women whose disease has spread, African Americanwomen have a significantly lower five-year survival rate.

“The ACS report underscores the importance of awareness andearly detection in saving lives,” said Susan Braun, president andchief executive officer of the Komen Foundation. “This messagecontinues to remain at the heart of the Komen Foundation’sbreast cancer awareness and education programs. The wideningdisparity in breast cancer mortality rates between white andblack women is unacceptable. It raises many questions andconcerns about socio-economic factors, which are often at theroot of limited access and poorer quality of care received.”

Braun also said that early detection and prompt, appropriatetreatment are key to improved survival. For women living inpoverty and outside the reach of quality medical care, detectionand diagnosis of breast cancer often come later, when thedisease is more advanced and less treatable.

“The report calls to the Komen Foundation and other advocacyand health organizations to maintain an intense focus on medicallyunderserved populations within our society,” Braun said.

The text of the entire ACS report is available atwww.cancer.org/statistics. �

Newly ReleasedFigures UnderscoreImportance of Early Detection

Young Women Taking Care(Item No. 806-01446-EN) isthe title of a new bookletwritten especially for youngwomen. The booklet has alsobeen translated into Spanish,Estamos Cuidando NuestrasVidas (Item No. 806-01446-SP). The booklets includeawareness messages aboutbreast cancer, the three-stepapproach to breast health anda pull-out Breast Self-Exam(BSE) card. The 81⁄2" x 51⁄2"booklets contain colorful,diverse and attractive graphicsas well as personal stories ofyoung breast cancersurvivors. These are greatresources for breast healtheducation for young womenand are written at a fifth-grade reading level.

Young Women Taking Care Posters (Item No. 806-08446-EN and Item No. 806-08446-SP) are two colorfulnew posters for youngwomen. The poster isavailable in Spanish andEnglish, features a diversegroup of young women andincludes an awarenessmessage for breast cancer and the three steps to breasthealth.

Educational MaterialsMonograph: Women’sInformational Needs Assessment(Item No. 806-08500) is a 43-page report describing theprocess, design and findings ofa nationwide assessment ofwomen’s needs for breasthealth and breast cancerinformation. The studyincluded both women who hadnever had breast cancer andbreast cancer survivors. Youngwomen (20-39) and women ofcolor (40+) were surveyed infocus group settings or intelephone interviews. Inaddition, healthcare providerswere surveyed for their insightinto the information needs ofthe women they serve.

Results included themes forthe delivery of information,content for education materialsand preferences for sources ofbreast health and breastcancer information. This is agood resource for grantees orcommunity groups who aredeveloping educationalmaterials for these specificaudiences. It can be orderedby calling 1.877.SGK.SHOP.The monograph is alsoavailable in a downloadablePDF file at www.komen.org.Look for it in the Educationsection under Resources.

(continued on page 7)

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(Educational Materials continued from page 6)

A New Look!Conceptos Basicos Sobre la Salud delSeno (Breast Health Basics) (Item No.806-302-SP) is a colorful 8" x 11"Spanish language flyer targeting youngwomen. It has been redesigned toinclude new messages, graphics andlayout. It still covers importantinformation on general breast cancerfacts and statistics, risk factors andbreast health. Designed for a youngeraudience, this education piece is great for education andoutreach among Hispanic/Latina women. This piece is alsoavailable in English (Item No. 806-302.)

These materials can be purchased by calling 1.877.SGK.SHOPor by visiting our Web site at www.komen.org. �

OUR RESEARCHERS: DEDICATED TO THE PROMISEOUR RESEARCHERS: DEDICATED TO THE PROMISE

Margaret E. Huflejt, Ph.D.Sidney Kimmel Cancer CenterSan Diego, California

The Research: Dr. Huflejt studiesspecific biological changes that areimplicated in the development of breastcancer. Through the analysis of humanbreast tissue, she has uncovered a protein

called galectin-1, a tumor-promoting protein that is found ingreater numbers in cells of breast cancer patients than in those of patients who do not have breast cancer. Dr. Huflejtproposes that galectin-1 works by blocking the action ofimmune cells, the body’s natural defense against disease. Dr. Huflejt and her team are testing synthetic sugar-likecompounds that effectively block galectin activity and inhibittumor growth and metastasis. The overabundance of galectin-1in breast biopsies may allow doctors to predict a breast cancerpatient’s response to various types of therapies. Measurementsof galectin may someday serve as an early warning sign forrisk of developing breast cancer. Dr. Huflejt’s current focus ison developing a non-toxic treatment that will promote thebody’s own immune system to suppress cancer.

The Galectin Family: Galectins are a family of multi-functional, sugar-binding proteins that, when formed inabundance, may play a role in the development of breastcancer. Some galectins help cancers to grow by building

resistance to the body’s natural ability to kill cancerous cells;others facilitate metastasis, or the spread of cancer. Somegalectins act as immune system suppressors, while otherspromote the formation of tumor blood vessels, which help themto grow. The roles of each galectin family member can change,depending on whether they are attached to the surface of the cellor are located within the cell. Most normal healthy breast tissuesexpress extremely low amounts of galectins. In fact, very littlegalectin is needed to sustain functions of healthy tissues. Anoverabundance of galectin-1 may be an indicator of a problem.

Battle Plans: The ultimate goal of this research is to introducenon-toxic galectin inhibitors as anti-breast cancer therapy.Depending on the type of breast cancer, these compoundswould carry out their work alone, or in combination with other therapies. To develop appropriate treatment strategies,researchers need to know more about what happens incancerous and pre-cancerous cells and tissues. Valeri V.Mossine, Ph.D., a collaborating researcher at the University of Missouri in Columbia, has developed a library of simple,synthetic sugar-based galectin blockers called lactulose aminesthat are very promising potential drugs. By attaching togalectins, these compounds inactivate them. Dr. Huflejt hastested several lactulose amines of potential clinical value in pre-clinical trials. Some of these compounds slowed tumor growth,with no evidence of toxicity. Others, when combined withother types of immunotherapies, showed evidence of completetumor eradication. Clinical trials involving humans could takeplace in as little as two years. �

More than 20 years ago, Nancy Brinker promised her dying sister, Suzy, that she would do everything possible to put an end to breast cancer. Nancy could not do the job alone,though — she needed the help of others who were committed to eradicating breast cancer as a life-threatening disease. Our Researchers: Dedicated to the Promise is a regular feature that spotlights the work of one of the Komen Foundation’s key partners in the fight against breast cancer — the researcher.

(Brinker Awards continued from front cover)

Dr. Bissell joined the Lawrence Berkeley National Laboratoryas a staff biochemist in 1972. She became a senior scientist in1977 and director of cell and molecular biology in 1988. Shewas appointed director of the life sciences division in 1992 andwas recently named a distinguished scientist and senior advisorto the laboratory director on biology.

Dr. Bissell has authored more than 200 publications and hasreceived numerous awards and citations. She received the 1996Ernest Orlando Lawrence Award and Medal and was elected tothe Institute of Medicine of the National Academy of Sciences in1997. In 1998, she received the Mellon Award from the Universityof Pittsburgh and was the 1999 recipient of the Eli Lilly/ClowesAward of the American Association for Cancer Research. In 2001,she received both an honorary doctorate from the Pierre & MarieCurie University in Paris and the “Innovator Award” of the U.S.Army breast cancer program. In 2002 she was elected to theAmerican Academy of Arts and Sciences. �

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Komen Affiliates Head to the Hill

On September 9, Komen Affiliates participating in the KomenChampions for the Cure™ grassroots policy program converged

in Washington, D.C., for a breast cancer summit on Capitol Hillhosted by the Komen Foundation. Affiliates from across thecountry walked the halls of Congress to meet with their senatorsand representatives to educate them about issues important tothe Komen Foundation and its many constituents and to ask forincreased public investment in breast health and breast cancercare. Komen Affiliate representatives provided insight tomembers of Congress and their staff about breast cancer issuesin their local communities and shared examples of what localKomen Affiliates are doing to make a difference back home.

The breast cancer summit also included a panel dinner discussionat which Affiliates were briefed on prevailing healthcare policyissues, such as cancer research funding and Medicarereimbursement for cancer care. Panelists included RhondaRichards, Democratic Staff Director, Senate Health, Education,Labor and Pensions Subcommittee on Aging for Senator BarbaraMikulski; Lori Rowley, Chief of Staff for Congressman RalphRegula, Chairman of the House Labor, Health and Human

Services Appropriations Subcommittee; Anne Phelps, formerSpecial Assistant to President George W. Bush for DomesticHealth Policy; and Kevin Brady, Deputy Director, Division ofCancer Prevention and Control, Centers for Disease Control andPrevention. After the informative panel presentations, KomenAffiliates had the opportunity to pose questions to the panelistsabout specific issues important in their local communities.

The Komen Champions for the Cure™ Affiliates forged manyimportant relationships with policymakers during the two-daybreast cancer summit in our nation’s capital and returned totheir local communities with a renewed sense of purpose andcommitment to bringing an end to breast cancer.

To learn more about how you can help make importantchanges in breast health and breast cancer public policy,please visit www.ActNowEndBreastCancer.org. �

C A P I T O L H I L L U P D A T E

For the eighth year in arow, Lee Jeans, with

the help of more than24,000 companiesnationwide, is expected toraise $7 million for thefight against breast cancer.One hundred percent of alldonations go directly to the

Komen Foundation to support breast cancer research,education, screening and treatment programs.

Lee National Denim Day® is the world’s largest single-dayfundraiser for breast cancer. On October 10, companies allowedemployees to wear jeans to work in exchange for an individual $5donation to the Komen Foundation. Since its inception in 1996,Lee National Denim Day® has raised more than $36 million tosupport the Komen Foundation’s fight against breast cancer.

At a special celebration at the Lee headquarters in Merriam, KS,Gordon Harton, president of Lee Jeans, and Kathy Collins, vicepresident of marketing, presented a check for $7 million(representing anticipated proceeds from this year) to Susan Braun,president and chief executive officer of the Komen Foundation.

Lee National Denim Day® Raises Millions ofDollars to Fight Breast Cancer

“We are continually inspired by the stories we receive each yearfrom those who have battled, are battling and hope to preventbattling breast cancer,” said Collins. “This program means somuch to so many people nationwide and Lee Jeans willcontinue the Lee National Denim Day program until a cure forbreast cancer is found.”

Braun accepted the check on behalf of the Komen Foundation.“Every year Lee National Denim Day is such an inspiration tous as individuals across the country joined together to help fightbreast cancer. Funds from this program are wisely spent eachyear on much needed research and local outreach programs thatshare the common goals of finding a cure for breast cancer andhelping those facing breast cancer today,” she said.

Actress Christina Applegate, Lee National Denim Day®

spokesperson and star of recent movies including View From theTop and the Sweetest Thing, took part in the special celebrationand check presentation at Lee. Applegate spoke in honor of hermother, Nancy Priddy, who was diagnosed with breast cancerwhen Christina was seven years old. �

Susan Braun, Christina Applegate and Kathy Collins

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P A R T N E R S I N T H E P R O M I S EWheatables Launches New Initiative

The Komen Foundation andWheatables crackers have

launched a new outreach andfundraising campaign calledTalk About Breast Cancer — It’s aConversation Worth Having tosupport the fight against breastcancer. The campaign wasdeveloped in response to anational survey recently

conducted by Wheatables crackers and the Komen Foundationthat showed nearly two-thirds of women surveyed never orrarely talk about mammograms and breast self-exams withloved ones or friends. And this is despite half reporting havingbeen personally touched by the disease.

To help get the dialog started, the Komen Foundation hasincluded conversation starters — ways women can encourageand remind others to practice regular breast health activities— on its Web site at www.komen.org. Wheatables crackersfeatures the same information on its packaging too, and hasalso agreed to donate $5 to the Komen Foundation for everyfive official pink ribbons clipped from its box tops and sent inby customers. Pink ribbons can also be clipped from packagesof other Keebler and Kellogg brands participating in the“Ribbons for Life” promotion, including Fudge ShoppeClusters, Vienna Fingers, Pecan Sandies, Nutri-Grain CerealBars and Special K Bars.

Through the program, they hope to raise up to $250,000 tosupport the Komen Foundation’s breast cancer research andcommunity outreach programs. Wheatables crackers will alsobe participating in select local Komen Race for the Cure®

events, with booth activities and giveaways that help women“get the conversation going.” Wheatables crackers is alsorunning a national magazine advertising campaign toencourage consumer participation in the campaign.

Recently, the campaign also included a breast cancer“conversation starter kit” in celebrity gift bags at the 2003Daytime Emmy Awards event in New York City. Celebritieslike Susan Lucci, Donny Osmond and Sharon Osbourneenjoyed the goodie bags. Each shared their own personal storyabout how they had been touched by the disease.

25 Yoplait Champions Honored

On September 23,Yoplait, the Komen Foundation and SELFmagazine honored the 25 Yoplait Champions — 25

ordinary women and men doing extraordinary things in theirlocal communities to support the fight against breast cancer.The 25 Yoplait Champions were selected after a nationwidenomination process designed to highlight the “power of theindividual” in the breast cancer cause.

“The stories of these Championsare truly inspiring. Theirexperiences serve as proof thatindividuals can make a significantdifference in fighting breastcancer,” said Camille Gibson, vicepresident of Yoplait. “It’s an honorto collaborate with the KomenFoundation and SELF magazine onthis program as Yoplait continuesto look for ways to extend itssupport of this important cause.”

The 25 Yoplait Champions are:

To commemorate this honor, Yoplait will donate $1,000 to eachChampion’s charity of choice that focuses on the breast cancercause. In addition, the 25 Yoplait Champions received a glasstrophy during a special ceremony held at SELF magazine’sheadquarters in the Condé Nast building in Times Square.Hotel accommodations for all the Champions were providedby Yoplait and airline travel to New York was provided byAmerican Airlines. For more information regarding the Yoplait25 Champions, visit www.yoplaitusa.com.

For the third year Yoplait is the National Series PresentingSponsor of the Komen Race for the Cure®. In addition tosupporting the Komen Race for the Cure®, Yoplait sponsorsthe highly successful Save Lids to Save Lives® program, whichtakes place throughout September and October each year. Foreach pink lid mailed in by consumers, Yoplait donates 10 centsto the Komen Foundation (up to $1.2 million).

(continued on page 10)

Jenny Enochson of Keebler, actress Susan Lucci and Jennifer Halpin of the Komen Foundation at the 2003Daytime Emmys

Kim Carlos, Kansas City, MOGeorgia Ellis, Wichita, KSCindy Geoghegan, Wilton, CTMara Ginsberg, Delmar, NYMark Goldstein, Randolph, NJJay Grogan, Dallas, TXSherrill Jackson, St. Louis, MOMargaret Kelly, Greenwood Village, COThe Kilimanjaro Climbers, Birmingham, ALDon Klimkiewicz, Chesapeake, VACapri Lober, Kansas City, MOLinda Lovato-Montoya, Albuquerque, NMJulie McQueen, Holly Springs, NC

Lindsay Nohr, New York, NYJudy Pickett, Cameron Park, CABeth Sabo, West Haven, CTMimi San Pedro, Little Rock, ARSusan Shinagawa, San Diego, CARochelle Shoretz, Teaneck, NJVal Skinner, Bay Head, NJDebra Smalley, Lakeside, AZMargaret Stothart, Matthews, NCVicki Tosher, Englewood, COJoy West, Greenville, SCMattye Willis, Little Rock, AR

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P A R T N E R S I N T H E P R O M I S E(contined from page 9)

Get Tied to the Cause with Ford

Ford Division, a major supporterin the fight against breast cancer,

has teamed with Lilly Pulitzer todesign the 2003 Ford breast cancerawareness silk scarf to help raisemoney to support the KomenFoundation’s mission to put an end tothe disease. To date, scarf sales have

more than doubled those of last year.

“We’ve been pleasantly surprised by the overwhelming demandfor the scarves,” said Steve Lyons, Ford Division president. “We are excited to see public supportgrow each year, and moreimportantly, to see breast cancersurvival rates continuallyimprove.”

Ford’s limited-edition silk scarf isa playful design of pink andgreen, incorporating a LillyPulitzer flower and butterfly pattern as well as the pinkribbon, the universal symbol for breast cancer awareness. It isthe third scarf in Ford’s Get Tied to the Cause campaign. The 12"x 56" scarves are on sale for $30 at Bloomingdale’s and at LillyPulitzer® Signature Stores while supplies last. They can also beordered at komen.org. All net proceeds from the sales benefitthe Komen Foundation.

Ford’s campaign, called “Get Tied to the Cause,” involves ahost of celebrities, including Oscar winner Helen Hunt, actorPeter Krause and tennis champion Serena Williams, whoappear in a series of magazine advertisements to raiseawareness of the disease and its reach. Other celebritiesappearing in the ads include Sarah Michelle Gellar, RosarioDawson, Regina King, Marg Helgenberger, Natalia Livingstonand Leslie Charleson. Each celebrity has a personal story totell about his or her experience involving breast cancer, andthose stories are reflected in the ads. The ads feature eachcelebrity using the scarf in creative ways: as a belt, ahandkerchief, a head wrap or even as a scarf.

In addition to the scarf, Lilly Pulitzer created a uniquelydesigned bandanna that Ford is distributing at Komen Race forthe Cure® events nationwide. Ford is a National Series Sponsorof the Komen Race for the Cure®. Approximately 500,000bandannas are being distributed free throughout the year.

Blair Corporation Is 2003Virtual Race Sponsor

Apartnership with BlairCorporation this year has

helped the Komen Foundation inits efforts to reach out to newcommunities to allow people toparticipate in the fight againstbreast cancer online, anytime.

As the 2003 Komen Virtual Race for the Cure® sponsor, BlairCorporation, a national multi-channel direct marketer of appareland home products, has given $100,000 and invited millionsthrough its catalogs and Web site to join in the fight against breast cancer.

A dedicated Web site at www.komenvirtualrace.org welcomessupporters to create or join a Komen Virtual Race Team andmake a difference with a donation to help the team reach itsfundraising goal. The interactive Web site encourages peopleto also share their photos and stories of triumph to help othersgain strength and courage. Blair Corporation is supporting acompany team and, through its own promotional offerings, isencouraging online visitors to join its customers and associatesin this important fundraising effort.

This is the second year Blair Corporation has partnered with theKomen Foundation through an online awareness and fundraisingcampaign. Last year, Blair’s interactive campaign linked visitorsto educational information at www.komen.org and, with thecompany’s pledge to donate $1 per online customer order placedat its Web sites Blair.com and CrossingPointe.com in October2002, raised $75,000 for the breast cancer fight.

“We are pleased to support the Komen Foundation’s efforts inincreasing education of the importance of early detection andsupporting advancements in breast cancer research, screeningand treatment,” said John Zawacki, Blair Corporation’spresident and CEO. “We believe the breast cancer cause isvery meaningful to our customers and also resonates well withwho we are as a company.” �

The Komen Foundation is pleased to announce that in early 2004 you will have the opportunity to receive our new e-Newsletter. All you need is an e-mail address! To sign up to receive the free e-Newsletter, visit www.komen.org and

click on “Subscribe” at the top of the page. �

Coming in 2004!

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When the KomenFoundation was

established in 1982 all phonecalls were handled byFoundation staff — includingcalls from people in need ofbreast care information andassistance. By 1989 it hadbecome apparent that therewas a need for a nationalHelpline to accommodate theincreased number of phonecalls. In October of that year,1.800 I’M AWARE® waslaunched from a majormedical center’s telemarketingdepartment and all calls were handled by theirrepresentatives. In April 1992, the Helpline transferredto Foundation Headquarters,where it was staffed bytrained volunteers personallytouched by breast cancer.

Today, the Helpline is mannedby volunteers who go throughan extensive screening andtraining process that includesan orientation to theFoundation, nine hours ofclassroom training, a period ofauditing phone calls andongoing continuing education.The time each volunteerdedicates to the Helpline isinvaluable — each of thewomen on the Helpline helpanswer the more than 20,000calls from women and menacross the country on a yearlybasis. Calls come from thenewly diagnosed and those whoare concerned about the menand women in their lives whoare facing breast cancer. What these and countlessothers receive is the warm,compassionate voice of ourdedicated volunteers. Pleasetake some time to read abouta few of our dedicatedHelpline volunteers.

Volunteer Voices

Helpline VolunteersFerne Painter,a 10-yearsurvivor,rememberswhen she foundout she neededto have abiopsy in 1993.

She was extremely anxious andnervous. She didn’t wantanyone to know about heranxieties, especially herimmediate family. When Fernecame across the 1.800 I’MAWARE® Helpline number, shecalled immediately and talkedwith a volunteer who she saysbecame her guardian angel.After her initial call she calledback several more times, alwaysreassured by the helpfulinformation she received. Fernebecame a Helpline volunteermore than nine years agobecause she wanted to providesupport for others facing similarsituations. “I have met somereally wonderful people andhave come to truly love them.”

Joan Kerrwas diagnosedwith breastcancer in 1991and has been aHelplinevolunteer for12 years. She

found out about theopportunity to volunteer onthe Helpline through herbreast cancer support group.Joan has touched so manylives through the Helpline. Infact, some callers call Joan tocheck in every once in a whileto tell her how they’re doing.Joan recalls a specific timewhen she counseled a womanwho was contemplatingsuicide after her diagnosis.The woman did not take herown life and still checks in

with Joan every now andagain. She credits Joan withsaving her life! “Knowing that Ihave helped at least one personsatisfies me more than anythingand that is why I keepvolunteering every week!”

Mila Ramosfirst beganvolunteeringwith theHelplinealmost threeyears agowhen her

youngest son literally foundthe Komen Foundation forher. One year after herdiagnosis and treatment forbreast cancer, Mila washaving a difficult time talkingabout her diagnosis. Her sonbegan looking for a place forher to interact with othersurvivors and came across theKomen Foundation. “I thinkthis is what my Mom wouldwant,” he said. After her firstmeeting at the KomenFoundation, Mila knew shehad found her niche. Todayshe will tell you that theHelpline is her therapy. Shefound her strength and nowcontinues to pass it along tothe women and men who callthe Helpline.

As one of theoriginalvolunteers onthe Helpline,Pat Hamer hasdevoted almost11 years to thecallers on 1.800

I’M AWARE®. As a survivorwith a very extensive familyhistory of breast cancer, sheenjoys talking to people andoffering emotional and practicalsupport.

Pat recalls a very emotionalphone call from several yearsago with a young woman whohad just been newlydiagnosed. After spendingalmost three hours on thephone with the woman, Patstill thinks of her to this day.She wonders about her andthe many others that shespeaks to on a weekly basis.She wonders how theirtreatment has progressed orhow a loved one is coping with the diagnosis. It is thepeople who care that keep her coming back.

It was almostsix years agothat Jill Beebeganvolunteeringon the Helpline.Jill had been a longtime

volunteer on the national leveland saw an opportunity to beof help and directly impactthose touched by breastcancer. Having lost her motherto breast cancer at the age offifteen, Jill recognized theimportance of the Helplineand felt it was a naturaltransition from her previousvolunteer work with theFoundation. Jill is a uniqueHelpline volunteer because,although she is not a survivor,she can empathize with thecallers and offer much neededsupport. She says she gets tolaugh and cry with the callers,but prefers the laughter. Beingable to navigate peoplethrough breast cancer,whether it is a new diagnosisor someone coping with thefinal stages of the disease,keeps her passion for theHelpline strong. �

Ferne Painter

Mila Ramos

Jill Bee

Joan Kerr

Pat Hamer

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K O M E N A F F I L I A T E N E W SLaugh for the Cure™

The Komen CharlotteAffiliate proudly

presented its third Laugh forthe Cure™ on August 26,2003. The grassroots event,sponsored by GrantThornton and hosted by TheComedy Zone, was foundedby a group of volunteers inCharlotte in July of 2002

and has quickly become one of the city’s most anticipatedcharity events. The evening included a business vendor expo,silent and live auctions and a comedy show featuring JustJune and headlining Mark Klein.

Night in SacramentoFilled with Surprises

It was a night full ofsurprises as the Sacramento

Monarchs, Sacramento Kingsand the Komen SacramentoAffiliate teamed up to raiseawareness about breast healthand breast cancer. More than120 breast cancer survivors

participated in a Sacramento Monarchs pre-game receptionhosted by Sutter Home Winery and attended by SacramentoMonarch Edna Campbell and Sacramento King Bobby Jackson.Survivors took the court at halftime and received high-fives fromall of the home and visiting team players.

During a second half time-out, Sutter Home Winery presenteda check to Komen Sacramento Affiliate Executive DirectorDonna Sanderson, representing a 50-cent donation for everyticket sold. Then, in a surprising move, Bobby Jacksonappeared and offered to match the amount. The crowd showedtheir approval with rafter-lifting cheers. Before everyone couldleave the floor, Joe Maloof, co-owner of Maloof Sports andEntertainment, stepped onto the court and also offered tomatch the donation. The audience went wild. Once in thetunnel, Donna, still stunned from the earlier events, was againsurprised and delighted as she was presented with anothergenerous check from Sacramento King Chris Webber insupport of Bobby Jackson and in memory of Bobby’s momwho died this past year of cancer.

Race Inspires New Pink ’Do

The Komen Northeast Louisiana Race for the Cure® tookplace on Saturday, September 13 and was a big success,

thanks to Affiliate President Doris Fandal who promised to

leave the Race site withpink hair if more than 3,000individuals entered theRace. Having met that goal,she invited two survivorbeauticians, Jeana Chastainfrom McMinnville, OR, andMary Morris from Borger,Texas, onstage during thesurvivor ceremony andallowed them to spray her hair pink.

Pink in the Rink

A s part of its sponsorship of the Komen Houston Race forthe Cure®, Polar Ice Galleria painted the Race date and a

Be a Friend for Life graphic (featuring a giant pink ribbon)underneath the ice at the Houston Galleria. In the four weeksleading up to the Race, thousands of Galleria shoppers viewedthe design, helping increase this year’s Race participation to25,000 people.

Iowa Approves NewLicense Plate

Iowa Governor TomVilsack recently signed a

bill to authorize a newbreast cancer license plate.The license plate will cost$35 and all proceeds will goto screenings andmammograms for theunderserved of Iowa. TheIowa license plate features a

pink ribbon to help increase breast cancer awareness andremind drivers to get screened. Josette Daum, a boardmember of the Komen Des Moines Affiliate, helped lead thecharge in driving this bill through the Iowa Congress.

New York City Salutes Survivors

To kick off this year’s Komen New YorkCity Race for the Cure®, Ann Taylor

hosted its eighth annual Salute to Survivors onThursday, September 4 at the Ann Taylorflagship store located at Madison Avenue and60th Street in New York City.

Over 450 guests, mostly breast cancer survivors, attended theSalute to Survivors event. The fashion show included 12stunning survivor models sporting Ann Taylor Loft and Ann

(continued on page 13)

Feature act Just June; headlining comedian Mark Klein and The Comedy Zone ownerBrian Heffron

Joe Maloof, Shawn Allen, Bobby Jacksonand Donna Sanderson

Lynn Redgrave

Jeana Chastain, Mary Morris and Doris Fandal

Karen Harper, Komen Des Moines Affiliate president; Laura Ernzen, Komen Quad CitiesAffiliate representative; Josette Daum, KomenDes Moines Affiliate board member; andGovernor Tom Vilsack

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K O M E N A F F I L I A T E N E W S(New York continued from page 12)

Taylor fashions. In a poignant ceremony, each survivor hadtheir survivor story read as they descended the spiral staircasein the center of the multi-level flagship store.

Actress and survivor Lynn Redgrave was the keynote speakerof the evening. Former First Lady of the City of New YorkDonna Hanover, CNN American Morning anchor SoledadO’Brien and NBC4’s Jane Hanson also attended.

Indianapolis Affiliate Receives Award

On Wednesday, October 1, 2003, the Komen IndianapolisAffiliate was pleased to kick off National Breast Cancer

Awareness Month by accepting the award for “Best OrganizationWorking to Increase Breast Cancer Awareness” given by theIndiana Breast Cancer Alliance (IBCA) during the Illumination2003 event held at the Indianapolis Artsgarden. StephanieMannon, executive director of the Indianapolis Affiliate, acceptedthe award and gave credit to all Affiliate volunteers workingtirelessly toward the Komen Foundation’s mission of eradicatingbreast cancer as a life-threatening disease. Mannon also linked theAffiliate’s ability to raise awareness to Komen granteeorganizations, such as the Little Red Door Cancer Agency, anIBCA member. All survivors in attendance were also recognizedfor their courageous battles with breast cancer.

New Orleans HonorsSurvivors

The Komen New OrleansAffiliate celebrated the

women who have battledbreast cancer at its annualSalute to Survivorsluncheon, held Wednesday,September 3 in the GrandBallroom of the Wyndham

New Orleans at Canal Place.

Cokie Roberts, author, National Public Radio senior analyst,political analyst and breast cancer survivor, was the guestspeaker, sharing relevant tidbits from her books and discussingthe forward movement of women’s health initiatives.

Lisa Westbrook Plunkett, Cokie Roberts and Patricia Denechaud

“Change has come because of women’s power and women’svoices making a difference,“ she said. Referencing her best-selling book, We are Our Mothers’ Daughters, Roberts paid tributeto her own mother, former Ambassador and CongresswomanLindy Boggs, who also attended the luncheon. Roberts’ wordsechoed those of Alan Stolier, M.D., medical director of surgicaloncology at the New Orleans Cancer Institute Baptist Campus,who described medical advances in breast cancer treatment inthe last 25 years as “lightning-like,” due in large part to theempowerment of women.

State Senator Diana E. Bajoie, also a breast cancer survivor,shared her story and asked other survivors to stand as themembers of the Louise S. McGehee Ensemble passed outcongratulatory roses and a copy of Barbara Delinsky’s book,Uplift, to each woman.

Columbus VolunteerReceives CommunityService Award

For her dedication andservice to the Komen

Columbus Affiliate, attorneyand 1971 graduate of TheOhio State UniversityMoritz College of Law,Susan E. Brown, received

the Moritz College’s 2003 Community Service Award during aceremony on Wednesday, August 13 at the Ohio State FacultyClub. The presentation, which was made by the HonorableThomas J. Moyer, chief justice of the Supreme Court of Ohio,was part of a reception for incoming law students.

The Community Service Award is given annually to the lawgraduate who has volunteered significant and sustained timeand expertise to assist a local, state, national or internationalhumanitarian organization.

For nearly 10 years, Brown has been involved with the KomenColumbus Affiliate, including serving as board president from 2000-2002. At the end of her tenure, she was awarded a Komen Cameo Award, given in recognition of heroutstanding leadership. �

Thomas J. Moyer, Susan E. Brown and Helen Brown, Susan’s mother

The Komen Foundation would like to recognize attorney Molly Richard and the Dallas-based law firm of Thompson & Knightfor the hundreds of hours of pro bono legal services they annually provide the Foundation. �

Thank You!

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Jun 12 Davenport, IAJun 12 Raleigh-Durham, NCJun 12 St. Louis, MOJun 12 Washington, D.C.Jun 13 Albuquerque, NMJun 26 Decatur, ILJul 3 Brainerd, MNJul 4 Greeley, COJul 17 Aspen, COJul 25 Manchester, VTAug 8 Colorado Springs, COAug 8 Kansas City, MOAug 28 Cheyenne, WYSep 5 San Francisco, CASep 11 Lexington, KYSep 11 Monroe, LASep 11 Scranton, PASep 12 Boston, MASep 12 New York City, NYSep 18 Shreveport, LASep 18 Tulsa, OKSep 19 Bangor, MESep 19 Evansville, INSep 19 Milwaukee, WISep 19 Portland, ORSep 19 Toledo, OHSep 25 Amarillo, TXSep 25 Grand Rapids, MISep 25 Greenville, SCSep 25 Kalamazoo, MISep 25 Lubbock, TXSep 25 Wichita, KSSep 26 Chattanooga, TNSep 26 Coeur d’Alene, IDSep 26 Orange County, CAOct Cleveland, OHOct Virginia Beach, VAOct 2 Albany, NY

Oct 2 Baltimore, MDOct 2 Birmingham, ALOct 2 Charlotte, NCOct 2 Chicago, ILOct 2 Houston, TXOct 2 Little Rock, AROct 2 Oklahoma City, OKOct 2 Tampa Bay, FLOct 3 Denver, COOct 3 New Orleans, LAOct 3 Omaha, NEOct 3 Reno, NVOct 9 Des Moines, IAOct 9 Knoxville, TNOct 9 Louisville, KYOct 9 Wichita Falls, TXOct 10 Phoenix, AZOct 16 Dallas, TXOct 16 Lenoir, NCOct 16 Miami, FLOct 16 Terre Haute, INOct 16 Texarkana, TXOct 16 Thibodaux, LAOct 17 Princeton, NJOct 17 Temecula Valley, CAOct 23 Charleston, SCOct 23 Fresno, CAOct 23 Jacksonville, FLOct 23 Macon, GAOct 23 Memphis, TNOct 23 Tupelo, MSOct 24 Honolulu, HINov 7 Austin, TXNov 7 Nashville, TNNov 7 San Diego, CAFeb 2005 Los Angeles, CAMay2005 New Britain, CTDates subject to change.

Jan 31 West Palm Beach, FLFeb 22 El Paso, TXMar 6 Baton Rouge, LAMar 20 Lafayette, LAMar 27 San Antonio, TXApr 3 Jackson, MSApr 3 Waco, TXApr 10 Ft. Worth, TXApr 18 Tucson, AZApr 24 Cincinnati, OHApr 24 Fayetteville, ARApr 24 Indianapolis, INApr 25 Lansing, MIMay 1 Charleston, WVMay 1 Las Vegas, NVMay 8 Atlanta, GAMay 8 Boise, IDMay 8 Daytona Beach, FLMay 8 Ottumwa, IAMay 8 Peoria, ILMay 8 Richmond, VAMay 8 Sacramento, CAMay 8 Salt Lake City, UTMay 8 Syracuse, NYMay 8 Twin Cities, MNMay 8 Tyler, TXMay 8 Winston-Salem, NCMay 9 Minneapolis, MNMay 9 Philadelphia, PAMay 9 Pittsburgh, PAMay 15 Columbus, OHMay 15 Helena, MTMay 16 Elmira, NYJun 5 Detroit, MIJun 5 Madison, WIJun 5 Plano, TXJun 5 Seattle, WAJun 12 Buffalo, NY

Date Site Date SiteDate Site

International RacesMay 16 Rome, ItalySep Frankfurt, Germany

2004 Komen Race for the Cure® Series

For the most up-to-date information on the 2004 Komen Race for the Cure®Series, contact our automated hotline at 1.888.603.RACE or visitwww.komen.org.

This fall, the Johnson & Johnson Family of ConsumerCompanies once again launched an aggressive multi-media

awareness campaign to support the fight against breast cancerby encouraging women to practice good breast health habits. The theme of this year’s campaign, Making a Difference Together,was designed to encourage men, women, family and friends tojoin the fight against breast cancer.

This year, the Johnson & Johnson Family of ConsumerCompanies partnered with ABC Daytime television to createthree public service announcements featuring stars from ABC’sGeneral Hospital with breast health tips and an offer for a FREEbreast self-exam card provided by Johnson & Johnson

Johnson & Johnson

Making a Difference TogetherConsumer Products. Other means of spreading the wordincluded a nationwide Sunday newspaper insert reaching over45 million people, in-store displays as well as a Web sitewww.justforwomen.net with links to Komen Race for the Cure®

dates/locations and an offer to have a FREE breast self-examcard mailed to a friend.

This is Johnson & Johnson’s fifth year of commitment to theKomen Foundation as a National Series Sponsor of the KomenRace for the Cure®. Each year employees support Komen Racefor the Cure® events across the country and have beenrecognized for the largest employee team participation in theKomen Race in Princeton, NJ. �

frontline 15

Your Donation CanHelp Us EradicateBreast CancerThe simple act of writing a check or placing a donation on your credit card could quite literally save someone’s life. Any contribution (large or small) helps us continue ourquest in the fight against breast cancer.

Please accept my contribution to the Susan G. Komen Breast Cancer Foundation to support the Foundation’s breast cancer research, education, screening and treatment programs.

Name:

Address:

City: State: Zip:

Phone number:

E-mail:

Amount of contribution: $

❒ Check enclosed Charge to: ❒ American Express ❒ Visa ❒ MasterCard ❒ Discover

Card number:

Expiration date:

Name as it appears on credit card:

Signature:

If this donation is a tribute, please complete one of the following:

In honor of: (name)

In memory of: (name)

Please send the acknowledgment of this gift to:

Name:

Address:

City: State: Zip:

Please remember the Susan G. Komen Breast Cancer Foundation in your will andUnited Way, federal employee and local employee campaigns.

Increase your donation with employer matching funds.Many employers will match your personal donation. Check with your company formore information on matching gift programs. Employer matching gifts may also beavailable to you if you are the spouse of an employee, a retired employee or thespouse/widow/widower of a retiree.

❒ I have included the Komen Foundation in my will.

❒ I would like information on making a gift to the Komen Foundation through my

estate plan.

Mail this form and your donation to: The Susan G. Komen Breast Cancer Foundation P.O. Box 650309Dallas, Texas 75265-0309

Or, you may also place your donation on a credit card by using the secured server on our Web site at www.komen.org or by calling our National Toll-Free Helpline at1.800 I’M AWARE® (1.800.462.9273).

Hope Cardigan$68.00

Pink Ribbon Charm Watch$55.00

Small Rhinestone Pin$5.00

Marketplace

Purchaser Information (Please print clearly or type.)Name:Company:Address (no P.O. boxes):City: State: Zip:Daytime Phone:E-mail:

Pricing FormProduct Size Quantity Item Price Total Pink Ribbon Mug $ 16.50Pink Ribbon Socks $ 6.00Small Rhinestone Pin $ 5.00Lilly Pulitzer Pink Ribbon Scarf $ 30.00Pink Ribbon Charm Watch $ 55.00Hope Cardigan SM, MD, LG, XL, 2X $ 68.00Total Product CostAdd Shipping & Handling*Add Sales Tax**Total

Payment Options• Check enclosed payable to: The Susan G. Komen Breast Cancer Foundation• Charge to: ❒ American Express ❒ Visa ❒ MasterCard ❒ DiscoverCard number: Exp. date:Name on credit card:Signature:

Placing Your Order• Online: www.komen.org • Mail: The Susan G. Komen Breast Cancer Foundation• Tel: 1.877.SGK.SHOP P.O. Box 932361, Atlanta, GA 31193-2361• Fax: 1.877.581.7037 • Questions? Please call 1.877.SGK.SHOP

Shipping and Handling* (Based on Total Product Cost)$1-$100 = $7.50 | $101–$250 = 10.0% | $251–$500 = 8.0% | $501–$1,000 = 7.0% | Over $1,000 = 6.0% | USA only

Sales Tax**

Show your support for the fight against breast cancer with our unique line of pink ribbonmerchandise. Fifty to 80 percent of the purchase price of all products sold by the KomenFoundation will benefit the Foundation and the fight against breast cancer. To see moreitems, visit the Komen Marketplace at www.komen.org.

Lilly Pulitzer Pink Ribbon Scarf$30.00

Pink Ribbon Socks$6.00

Pink Ribbon Mug$16.50

AL 8.5%AR 7.6%CA 8.25%CO 6.7%CT 6%DC 5.75%

FL 7%GA 7%HI 4%ID 6%IL 8.75%IN 6%

KS 7.3%KY 6%LA 4%MA 5%MD 5%ME 5%

MI 6%MN 7%MS 7%NC 7%NE 7%NJ 6%

NM 5.8125%NY 8.5%OH 6.5%OK 8.37%PA 6%RI 7%

TN 9.25%TX 8.25%UT 6.25%VA 4.5%VT 6%WA 8.3%

WI 5.6%WV 6%WY 6%

Headquarters

5005 LBJ Freeway, Suite 250

Dallas, Texas 75244

Tel: 972.855.1600 Fax: 972.855.1605

www.komen.org

1.800 I’M AWARE®

The Susan G. Komen Breast Cancer Foundation was founded on a promise made between two sisters — Susan Goodman

Komen and Nancy Goodman Brinker. Suzy was diagnosed withbreast cancer in 1978, a time when little was known about the diseaseand it was rarely discussed in public. Before she died at the age of36, Suzy asked her sister to do everything possible to bring an end to breast cancer. Nancy kept her promise by establishing the KomenFoundation in 1982 in Suzy’s memory. More than 20 years later, the Komen Foundation is a global leader in the fight against breastcancer through its support of innovative research and community-based outreach programs. Working through a network of Affiliatesand events like the Komen Race for the Cure®, the Komen Foundationis fighting to eradicate breast cancer as a life-threatening disease by funding research grants and meritorious awards and supportingeducation, screening and treatment projects in communities aroundthe world.

f r o n t l i n e n e w s l e t t e r Founder . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Nancy Brinker

Chair, Komen Foundation Board of Directors . . . . . . . . .LaSalle D. Leffall, Jr., M.D.

President and Chief Executive Officer . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Susan Braun

Editor . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Maureen O’Donnell

Non Profit Org.

U.S. Postage

PAID

The Susan G. Komen

Breast Cancer Foundation

The Komen Foundation recently launched an innovativepublic policy Web site, ActNowEndBreastCancer.org, which

will enable thousands of concerned Americans to join the fight against breast cancer. This virtual advocacy forum offersevery American the opportunity to influence the federalgovernment on crucial breast health and breast cancer carepublic policy issues.

“As a leading patient advocacy organization, the KomenFoundation is offering ActNowEndBreastCancer.org as aninnovative tool to empower Americans who want to learn aboutpublic policy that affects breast cancer research, prevention andaccess to treatment and have their say on how the nation shouldinvest and formulate policy in these areas,” said Diane Balma,director of public policy for the Komen Foundation.

To date, Komen e-Champions have generated more than 60,000letters to members of Congress about important breast healthand breast cancer care issues through the new site. To learnmore about how you can become a Komen e-Champion, pleasevisit www.ActNowEndBreastCancer.org. �

Komen FoundationLaunchesActNowEndBreastCancer.org