“Clinical Case Studies on Management of

Menopausal syndrome with

Ayurvedic Formulations”

By:

Dr. P.JyothiP.G.Scholar,

Kaya Chikitsa department,Dr.BRKR Govt.Ayurvedic Medical College,

Hyderabad.

Introduction: In woman’s life Menopause is a naturally occurring phenomenon. It is the period (typically between the ages of 45 and 50) when menstruation ceases.

Menopause happens because the woman's ovaries stop producing the hormones estrogens and progesterone

This episode of every woman’s life seems to be a bit troublesome to go with because of increasing incidence of many health aliments involved like:

Hot flushes or night sweats Trouble sleeping/ Insomnia Joint and Muscle aches and pains/ weakened bones Fatigue Depression Palpitations (Heart Racing) Vaginal dryness Mood swings Irritation Trouble focusing Loss of Libido Less hair on head, more on face etc.

But now with the help of evolving Ayurvedic treatment modalities and preventive measures this entire painful scenario of menopausal syndrome can be changed in to a blissful episode of Women’s life.

In Ayurvedic Classics, Menopause condition is termed as “Rajonivrutti” and various beneficiary measures used in treating Rajonivrutti anubandha Vyãdhies (menopausal syndromes/Symptoms) are very beautifully mentioned.

Hence an attempt of presenting Various Clinical trials carried out on few menopausal Symptoms and their concerned Ayurvedic preventive and curative measures with obtained results is initiated.

Aims and Objectives:

To Prove the Efficacy of Various Ayurvedic formulations in the Management of Menopausal Syndrome

To understand the Sustained curative effect of Ayurvedic drugs in treating Menopausal Symptoms

Materials & Methods:Source of data: 9 Patients attending OPD and IPD of Kayachikitsa

Department of Dr. BRKR Govt Ayurvedic Hospital, Hyderabad and those fulfilling required inclusive and Exclusive criteria were selected for study.

Inclusive criteria: Patients presenting with the one or more Menopausal symptoms Patients were selected between the age group of 40-60 years. Exclusive criteria: Patients below the age of 40 years and above the age of 60 years. Patients suffering from Diabetes Mellitus, Hyper -parathyroidism,

Paget’s disease, Thyrotoxicosis, Cushing’s syndrome, Endocrinal disorders and other serious systemic diseases were excluded.

Parameters of Study: Only subjective parameters like Hot flushes, Insomnia, Palpitations, Mood Swings, Depression, Muscle and Joint aches etc were selected for study.

Plan of study: 9 known cases of menopausal syndrome were selected for the study

after properly diagnosed.

Out of 9 patients 4 Patients c/o Hot flushes, Mood swings and Insomnia . Each patient was treated with

1. Satavaryadi Ghrita dose- 10ml, Twice a day, With milk, After food 2. Sankha Pushpi Syrup dose- 10ml, Twice a day, With water/milk, After food

3. Brahmi Vati dose- 1 tablet, Twice a day, With water/ milk After food

Also advised Siro pichu with Brahmi Taila, Abhyanga with Tila taila and pranaayama

Treatment duration- Continuous period of 3 months

Review - for every 10days.

Out of 9 patients, 2 patients c/o Palpitations. Each Patient was treated with

1. Arjuna Ksheera Paaka dose - 15ml,Twice a day, After food2. Ashwagandha churna dose – 5gm, Twice a day, with milk, After food

Treatment duration – 3 months Review – for every 10 days

Out of 9 patients 3 Patients c/o Both knee joints pain and Restricted movements of Lower limbs. Each patient was treated with

1. Kukkutanda tvak bhasma dose- 250 to 375mg, Twice a day, with milk/Honey, After food

2. Pravãla Panchaamrita Ras dose- 1 tablet, Twice a day, With honey/milk, After food Also advised Balaashwagandha taila Abhyanga and Anuvaasana

Vasti (in selected patients only)

Treatment duration - Continuous period of 4 months Review - For every 10 days

Result Assessment:

Results were assessed based on changes observed in subjective parameters before and after the treatment

Grading scale designed on Subjective Parameters of selected Menopausal symptoms is used for result assessment purpose

Grading scale for subjective parameters:Parameter Grade 0 Grade 1 Grade 2 Grade 3 Grade 4 Hot flushes No flushes Occasional very

mild hot flushes Intermittent mild hot flushes, once in 10-15 days

Frequent hot flushes

Severe hot flushes daily

Mood Swings Normal/Pleasant mood

Very mild mood swings

Occasional mood swings without irritation

Frequent mood swings with irritation

Continuous Irritation/aggressive/depressed mood

Insomnia Normal sleep Occasionally Mild disturbance in night sleep with duration of 6-7 hrs

frequently disturbed night sleep with4-5 hrs of duration

Disturbed sleep with only 2-3 hrs of night sleep

Complete disturbed night sleep

Palpitations No palpitations

Occasionally and very mild palpitations heard

Palpitations only with severe exertion

Severe Palpitations even with mild exertion

Severe palpitations even on rest

Knee joint pain

Free movements of both knee joints without pain

Very mild knee joint pains which occurs occasionally and can walk freely without support

Moderate knee joint pain and can walk freely with support

Moderate bearable Knee joint pains with swelling

Severe unbearable knee joint pain associated with swelling and restricted movements

Observations: The following are the observations of the study. Since it is a kind of pilot study conducted on different

menopausal symptoms, a total number of 9 patients only were selected.

Out of 4 patients c/o Hot flushes, Mood Swings and Insomnia

2 patients showed 100% symptomatic relief i.e. Grade4 to Grade1 1 patient showed 75% symptomatic relief i.e. Grade 4 to Grade 2 1 patient showed 50 % symptomatic relief i.e. Grade 4 to Grade 3

Out of 2 patients c/o Palpitations

1 patient showed 75% symptomatic relief i.e. Grade 4 to Grade 1 1 patient showed 50 % symptomatic relief i.e. Grade 4 to Grade 2 Out of 3 patients c/o Both knee joints pain and Restricted

movements of Lower limbs

1 patient showed 75% symptomatic relief i.e. Grade 3 to Grade 0 2 patients showed 50% symptomatic relief i.e. Grade4 to Grade 2

Representation of Observed results in tabular form

Parameter No. of Patients Before treatment After treatment % of Improvement

Hot flushes, 4 2 Severe hot flushes No flushes 100%

1 Severe Hot flushes Occasional very mild hot flushes

75%

1 Severe Hot flushes Intermittent hot flushes once in 10days

50%

Mood Swings 4 2 Severe irritation and intolerance

Normal or pleasant mood

100%

1 Severe Aggressive mood

Very mild mood swings

75%

1 Continuous depression

Occasional mild depression

50%

Insomnia 4 2 Complete disturbed night sleep

Normal sleep 100%

1 Complete disturbed night sleep

Mild disturbance with 6-7 hrs of night sleep

75%

1 Complete disturbed night sleep

Frequently being disturbed with only 4 hrs of night sleep

50%

Parameter No. of Patients Before treatment After Treatment % of improvement

Palpitations 2 1 Severe Palpitations even on rest

Occasionallyvery mild palpitations heard

75%

1 Severe Palpitations even on rest

Palpitations on severe exertion

50%

Knee joint PainsAnd restricted movements of both lower limbs

3 1 Moderate bearable knee joint pains with swelling

No pain and no swelling of both knee joints

75%

2 Severe unbearable knee joints pain with swelling and restricted movements

Occasional knee joint pains and can walk freely with support

50%

Overall Results: Marked improvement - >75% to 100% improvement Good improvement - >50%to <75% improvement Moderate improvement - >25% to <50% improvement Poor improvement - <25% improvement Overall result of this clinical case studies on different

Menopausal Syndrome is assessed to be as “Good Improvement”

Conclusion: Thus it can be concluded that with the help

of various Ayurvedic drugs/formulations and preventive measures, now every women can lead her menopausal life in a blissful way.

An attempt of presenting this clinical study on menopausal syndrome is made expecting it to be beneficiary for Ayurvedic research scholars and hence providing further scope to carry out even more research on this aspect.

Thank you