ASSESSING READINESS TO OFFER NEW DEGREE PROGRAMS

Master of Science in Biomedical Engineering, 08-05-2013Assessing Readiness to Offer New Degree Programs is a supplemental campus-based document that will

a) Inform the academic program development process and b) Illustrate the unit’s readiness to offer the proposed degree program.

The proposing unit is expected to a) Submit the assessing readiness document with the proposed program’s planning document and b) Update the assessing readiness document as unit conditions change for submission with the proposed

program’s request to establish.

Part One: Assessing Need for the Program

Need for the ProgramAs the population ages, the need for advanced medical tools, devices and diagnostics increases along with a need to improve our understanding of disease states. Thus as this need increases so does the demand for biomedical engineers. Due to their unique background, biomedical engineers have one foot grounded in the medical field and one foot grounded in engineering principles. By straddling these fields, biomedical engineers form a bridge upon which medical need, clinical practice, creativity, collaboration and research can travel freely from one side to the other. Our students will have a direct impact on the lives and health of those living in eastern North Carolina.

According to the Bureau of Labor Statistics, the employment growth for biomedical engineering will increase by 62% over the next ten years illustrating an increasing demand for people educated in this field as shown in Table 1. In addition the Labor Market Information Division of the Employment Security Commission of North Carolina predicts a 77% increase in biomedical engineering jobs from 2008-2018. Taking a snapshot of the statewide labor market, in October 2012, 4% - 10% of the biomedical engineering jobs advertised on the website ENGINEERJOBS.com were located in North Carolina. In addition, North Carolina Biotechnology Center’s NCBiotech company directory lists over 400 bioscience companies in the Eastern, Southeastern and Triangle regions of North Carolina. Many of these companies are focused on developing products for regenerative medicine, cardiovascular disease, diabetes, drug delivery and medical devices. Thus, there is a demand within the state of North Carolina for biomedical engineers.

Table 1: BLS Growth Projections (in thousands) for Biomedical Engineering and Related Occupations Lockard, C. B., & Wolf, M. (2012). Occupational employment projections to 2020. Monthly Labor Review Online, 135(1), 84–108. Retrieved from http://www.bls.gov/opub/mlr/2012/01/

Occupational title SOC Code Employment, 2010

Projected employment,

2020

Change, 2010-20

Number Percent

Biomedical Engineer 17-2031 15,700 25,400 9,700 62

With the anticipated growth in employment for biomedical engineers, the Department of Labor reports a graduate degree is recommended or required for many biomedical engineering entry-level jobs. As noted by the National Science Foundation and summarized in Table 2, enrollment in biomedical engineering graduate programs, which increased by 7.5% between 2009 and 2010, continues to be one of the fastest growing science and engineering fields and has experienced the most rapid growth over the last decade (165%), from approximately 3,200 graduate students in 2000 to 8,500 students in 2010. “Because of the growing interest in this field, the number of degrees granted in biomedical engineering has increased greatly. Many biomedical engineers, particularly those employed in research laboratories, need a graduate degree to be competitive”. (http://www.aimbe.org/in-the-news-bureau-of-labor-statistics-sees-rapid-growth-in-biomedical-engineering-jobs/). A recent search for biomedical

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engineering jobs on the job-site Monster.com, showed that 55% of the biomedical engineering jobs advertised required a bachelor’s degree while 30% required a master of science degree.

TABLE 2 - Nationwide graduate enrollment in engineering by field: 2000–10, [National Science Foundation/National Center for Science and Engineering Statistics, NSF-NIH Survey of Graduate Students and Postdoctorates in Science and Engineering. May 2012].

2000 2009Field 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 –10b –10

Aerospace engineering 3,407 3,451 3,685 4,048 4,089 4,170 4,482 4,616 4,902 5,266 5,540 65 5.2Architecturea ne ne ne ne ne ne ne 4,601 5,905 6,804 6,795 - -0.1Biomedical engineering 3,197 3,599 4,338 5,301 5,807 6,067 6,482 6,904 7,339 7,904 8,497 165 7.5Chemical engineering 7,056 6,913 7,414 7,516 7,452 7,173 7,261 7,584 7,892 8,188 8,668 25 5.9Civil engineeringa 16,451 16,665 17,713 18,890 18,561 18,114 17,802 16,071 16,931 18,638 19,559 20 4.9Electrical engineering 33,611 36,100 39,948 41,763 38,995 37,450 38,265 40,588 41,164 41,218 41,336 25 0.3Industrial engineering 12,119 12,940 14,033 14,313 13,852 13,650 13,829 14,474 15,692 15,825 15,205 25 -3.9Mechanical engineering 15,235 15,852 17,139 18,393 17,852 17,373 17,919 18,347 19,585 21,243 22,509 50 6.0Metallurgical/materials engineering 4,377 4,721 4,992 5,131 5,059 5,160 5,268 5,314 5,539 5,863 6,274 45 7.0Other engineering 8,659 9,252 10,406 12,022 11,899 11,408 11,733 13,177 12,907 13,728 14,858 70 8.2

% change

Graduates of the program will be highly qualified and prepared for positions in industry, government, and PhD, medical and dental programs at ECU and other UNC constituent institutions. Upon completion of this program students may also choose to enter the education profession, improving the Science, Technology, Engineering and Mathematics (STEM) teaching pool for eastern North Carolina.

Fit with Strategic PlanThis unique program, which targets an emerging and advanced technological field, integrates with key components of the ECU mission statement: to serve through education, to serve through research and creative activity, and to serve through leadership and partnership. The proposed MS in biomedical engineering is consistent with and supports these components. This MS program:

Offers a unique graduate education option preparing engineers and scientists to meet the challenges of biomedical discovery and applications of engineering to health care and medical innovation in service to the people of North Carolina, their health and their welfare.

Provides opportunities for partnership with the BSOM, SODM, College of Nursing, College of Allied Health Sciences, Thomas Harriot College of Arts and Sciences, College of Health and Human Performance, industry, government, and defense system organizations.

Enhances new and emerging research opportunities for faculty in the BSOM, SODM, College of Nursing, College of Allied Health Sciences and the Department of Engineering to form partnerships in an emerging field.

Focuses on development of technology professionals in a key field and promotes development of strong linkages and interactions with the industrial, business, and public sector organizations of eastern North Carolina.

Advances the art of biomedical engineering and in particular makes this important discipline available at the graduate level to regional biotechnology business and industry.

The proposed MS program specifically addresses the following ECU Strategic Directions and related sub elements as presented in ECU Tomorrow (www.ecu.edu/mktg/ecu_tomorrow):

Education for a new century: We will be responsive to the changing demands of the economy, offering excellent undergraduate and graduate programs that provide the global skills and knowledge necessary for success in the twenty-first century.

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Economic Prosperity in the East: We will invest in academic programs that give individuals the right skills and tools needed to compete and thrive in a twenty-first-century workplace. We will invest in programs that improve access to our resources for communities and individuals. We will provide ongoing educational and learning opportunities to support the continued development of a competitive workforce for North Carolina.

ECU will increase investment in innovation and research: We will be the third-largest research university in the University of North Carolina system, exceeding $100 million in external support for our programs. We will lead in innovation in health sciences and information technology and seek to develop products that compete in the growing knowledge-based economy. We will invest in interdisciplinary research centers that will support the region’s growth in health care, tourism, education, marine trades, and biotechnology. We will focus on developing applied, translational, and externally focused research that emphasizes the economic and physical health of our citizens.

Health Care and Medical Innovation: ECU will save lives, cure diseases, and positively transform the quality of health care for the region and state. ECU will expand our research in health sciences with a particular emphasis on the health concerns of the region and state. We will expand biomedical and health-related research funding to $75 million annually.

Biomedical engineering is a twenty-first century career field which meets the demands of the economy for excellent graduate programs, allowing ECU graduates to compete in the global economy. In addition, this degree will provide a positive economic impact, improving resources for the regional community to improve health care and jobs. Globalization of both engineering and the overall field of healthcare has been increasing over the past 10-20 years and is continuing to increase. Graduates of the proposed program will have a strong background in both fields and will compete and contribute to this growing global economy.

Since 2004, the ECU BS in engineering program has had a positive impact on industry and economic development in eastern North Carolina. Faculty from the biomedical engineering and bioprocess undergraduate concentrations work regularly with industry and economic development professionals from the region. The Department of Engineering’s active Engineering Advisory Board (EAB) includes two economic development professionals, one from Pitt County and one from the Eastern Region. The time and effort spent by the 40+ members of the EAB are testament to the fact that local industry cares very much about the program. A number of the EAB members are from healthcare-related industries, providing senior capstone project and internship opportunities. Senior biomedical engineering capstone projects have included partnering with NASA Langley Research Center, the Brody School of Medicine, College of Allied Health Sciences, and College of Health and Human Performance. In addition, undergraduate biomedical engineering students have participated in internships at RTI Biologics, Inc. (formerly Pioneer Surgical Orthobiologics, Inc.) in Greenville and Hospira, Inc in Rocky Mount, resulting in permanent employment upon graduation. Members of the EAB are strong contributors to the department.

The MS in biomedical engineering will have a positive impact on the research productivity of the university, support innovation in health sciences, support interdisciplinary research improving health care and biotechnology, and support overall improvement of the health of the citizens of North Carolina. By emphasizing the application of engineering and mathematics to medical research, the proposed program advances the university’s focus on improving student STEM proficiency.

Impact on other Unit ProgramsThe proposed program does not compete with any program within the Department of Engineering or within the College of Technology and Computer Science. This program will be the first engineering graduate program available at ECU.

More broadly and most important, the proposed MS in biomedical engineering complements many programs in a variety of colleges, schools and departments at ECU. For example, the new graduate engineering program integrates well with the MS in biomedical sciences, offered by the BSOM. The biomedical science program emphasizes basic science, medical, pharmaceutical, and biotechnology research. The proposed program will also integrate well with ECU’s interdisciplinary doctoral program in biological sciences (IDPBS). This program currently offers graduate curricula and research in the areas of biology, chemistry and biomedical sciences. The

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MS biomedical engineering program anticipates partnering with the College of Nursing and Doctor of Nursing Practice (DNP) program, recently approved by the UNC Board of Governors, to translate applied research from “bench to bedside” to improve health care delivery. The proposed MS program will complement these graduate programs, and will expand course selection for graduate students both in engineering and in the above disciplines. Drs. Muller-Borer and George are faculty participants in the IDPBS program. Dr. Muller-Borer is the graduate program director for the IDPBS biomedical science concentration. The experience gained in advising students in IDPBS will translate well to advising students in the proposed MS in biomedical engineering.

Currently, faculty from the School of Dental Medicine, Department of Kinesiology, Department of Physical Therapy, Department of Cardiovascular Sciences, Department of Physiology and College of Nursing collaborate with biomedical engineering faculty to enhance undergraduate education. This includes:

Lectures in biomaterials (Drs. deRijk and Collins, School of Dental Medicine) Lectures in biomechanics (Dr. Domire, Department of Kinesiology, Dr. Allison, Department of Physical

Therapy) Lectures in biomedical device applications (Dr. Sam Sears, Department of Psychology and

Cardiovascular Sciences) Introduction to basic science, robotics and biomechanics laboratories (Dr. Muller-Borer, Department of

Engineering and Cardiovascular Sciences, Dr. Nifong, Department of Cardiovascular Sciences, Dr. Domire, Department of Kinesiology, Dr. Allison, Department of Physical Therapy)

Senior capstone project sponsors (Dr. Muller-Borer, Department of Cardiovascular Sciences, Dr. Walters, Department of Physiology, Brody School of Medicine, Dr. Allison, Department of Physical Therapy, Dr. Rose, College of Nursing)

Undergraduate research opportunities (Dr. Muller-Borer, Department of Engineering and Cardiovascular Sciences, Dr. Virag, Department of Physiology, Brody School of Medicine, Drs. Rosenbaum, Oppelt and O’Rourke, Department of Comparative Medicine, Brody School of Medicine)

Multidisciplinary faculty research projects (Department of Kinesiology, Department of Cardiovascular Sciences, College of Nursing)

The average enrollment over the next five years is estimated to be approximately 5–7 students per year although this number is anticipated to increase when additional faculty are hired in the Department of Engineering. The five year cumulative enrollment target is 25 students. This program will attract quality students from the Department of Engineering’s BS program, Thomas Harriot College of Arts and Sciences, pre-med students with quantitative research interests, and basic science and engineering students from eastern North Carolina and across the state. Comparison to Similar Programs in Other UniversitiesCurrently, a master of science in biomedical engineering degree is offered at three public (NC A&T State University and UNC/NCSU) and two private (Duke University and Wake Forest University/VA Tech) North Carolina universities. According to the American Society for Engineering Education (http://www.asee.org/papers-and-publications/publications/college-profiles) the number of students graduating with a master of science in biomedical engineering from these universities (2008-2012) includes:

NC A&T State University – 0 (6 graduates in 2013, self report) UNC/NCSU - 15 Duke University - 159 Wake Forest/VT - 23

All of these graduate programs are located in central or western North Carolina and are located more than 85 miles to the west of East Carolina University. East Carolina University is the only university in eastern North Carolina (i.e., the region east of the I-95 corridor) to offer an engineering undergraduate curriculum. Except for UNC/NCSU which has focused on growing their doctoral program, enrollment and graduation rates at the master’s level have remained constant at these universities during this five-year period. To better understand the demand for this graduate program several other biomedical engineering master of science programs, similar in

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size and academics to ECU’s engineering program were surveyed. Master of science in biomedical engineering graduation rates (2008-2012) for these programs were:

Mercer University, GA – 16 University of Alabama Birmingham, AL – 41 Virginia Commonwealth University. VA – 53

These numbers are similar to those at NC universities and suggest a strong need for a master of science in biomedical engineering. It should be noted that none of these programs are located in eastern North Carolina.

Approximately 47% of the current ECU engineering students are from eastern North Carolina and 60% of the ECU Engineering alumni are from eastern North Carolina. Therefore, there is a need to be fulfilled within the state of North Carolina for the training of biomedical engineers, particularly in eastern North Carolina. East Carolina University has an advantage, both nationally and regionally, as the only university within the 17 University of North Carolina institutions that offers academic programs in engineering, medicine, dentistry, business, nursing and allied health on one campus. This proximity of complementary programs provides an unequaled opportunity for collaboration and professional growth of faculty, staff, and students.

This program will expand research and competitive, externally funded grant opportunities for faculty in engineering and other collaborating departments. The curriculum development team will design an innovative research intensive curriculum founded on engineering education research. Such an innovative curriculum would be competitive for extramural funding and national recognition.

Accreditation StandardsThere are no standard accrediting bodies for graduate programs in biomedical engineering.

Part Two: Assessing Readiness of Current Faculty

Complete the Faculty Information Sheet (attached, with instructions for downloading from Sedona) for each individual who will serve as a core faculty member, actively involved in delivering the proposed program.

Please see attached (page 17)

Provide a summary of faculty readiness in the unit to include the cumulative totals of the following:

Faculty Readiness Summary (with emphasis on the last five years)Number of core faculty at each rank who will be actively engaged in this program

Professor 2Associate Professor 3Assistant Professor 3Visiting Assistant Professor (new hire, 8/2013) 1Teaching Assistant Professor (new hire, 8/2013) 1

Number of core faculty with experience directing theses/dissertations 5Number of scholarly and professional activities related to proposed degree (with emphasis on the past 5 years):Number of publications related to proposed degree 140*Number of grants & contracts submitted and awarded related to proposed degree 42*Invited research presentations outside ECU 58*Patents/disclosures/copyrights 3*Participation in scholarly collaborations with other universities, laboratories, & centers:Number of faculty

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Service on related national/international boards or committees: Number of faculty 7* *These numbers are based on the eight core engineering faculty. We anticipate that the newly hired Visiting and Teaching Assistant Professors will supplement biomedical engineering undergraduate and graduate instruction.

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Part Three: Assessing Adequacy of Instructional/Research Facilities and Personnel to Support the Program

Instructional and Research Facilities The program can be initiated using current available space. The faculty associated with the proposed program will mentor graduate research using the equipment and facilities described below. This equipment, and the associated laboratory space, are already in place, and are actively used in current research and teaching.

The Department of Engineering supports a number of laboratories across several engineering disciplines.Within biomedical engineering, there are several laboratories housing a variety of equipment. Room 355 (650 sq. ft.) in the Science and Technology Building houses a complement of advanced electronics fabrication and test equipment. This equipment includes an MSO4054B 500 MHz mixed-signal oscilloscope; a Tektronix AFG3022B 25 MHz, dual-output arbitrary waveform generator; Tektronix P5205 high-voltage differential probe and ADA400 differential preamplifier; a TCP0030 current probe; and an Agilent 34410A digital multimeter. Room 243 in the Science and Technology Building is predominantly a teaching laboratory space. Within that space are several fully stocked electronics test benches, including Agilent E3631A triple-output power supplies; Agilent 34410A digital multimeters; Agilent 33220A, 20 MHz arbitrary waveform generators; and Agilent 5000 series oscilloscopes.

Additional high-end electronic measurement and test equipment is available in the Biosensors Research Lab. Specific equipment includes Agilent MSO6034A oscilloscope, 1682A logic analyzer, 6622A power supply, 34410A digital multimeter, 33220A function generator, Cadence P-SPICE, Electronics Workbench Multisim, soldering stations, wireless communication modules (Bluetooth, Zigbee) and development tools, medical sensors, personal computers, LPKF print circuit board rapid-prototype machine, Microchip Integrated Development Tools, software licenses for LabVIEW, MATLAB, Solidworks, and NI-ELVIS.

The Bioprocess Engineering Laboratory (1990 sq. ft.) is a teaching and predominantly research laboratory, located in the Science and Technology Building, room 131. Current courses in upstream bioprocessing (wet-lab techniques, bacterial cultures in both shaker flasks and benchtop bioreactors, and cell harvesting) and downstream processing (distillation, extraction, affinity chromatography) are taught in this laboratory each semester. The major equipment housed in the laboratory that is available for teaching and research includes two 5L and two 2L benchtop bioreactors (Sartorius BioStat Aplus), GE AKTA Purifier system, centrifuge (Beckman Coulter Avanti J-E), top loading autoclave for the bioreactors (Hirayama HICLAVE), front loading autoclave (Tuttnauer Brinkmann 2540E), table-top shaker/incubator, pH meter (Thermo Orions Star series), sonic dismembrator (Fisher Model 100), spectrophotometer (Perkin Elmer Lambda 45 UV/VIS), bath sonicator, analytical balance (Mettler Toledo), stir/hot plates, lyophilizer (Labconco Freeze Zone 4.5), luminometer (Promega Glomax 20/20), fluorometer (Promega, Modulus), three-door chromatography cabinet, protein and DNA electrophoresis equipment, thermal cycler, and small equipment and tools to conduct molecular biology research (micropipettes, table-top centrifuge, etc.).

In addition, this facility houses a TA Instruments AR-2000 stress-controlled Rheometer, an Olympus BX-51 reflected light microscope with a 12MP digital camera and bright field/dark field/fluorescence, and a ramé-hart Model 250 Standard Contact Angle Goniometer/Tensiometer for contact angle and surface tension measurements.

The Engineering Department maintains a variety of industrial quality fabrication and mechanical engineering instrumentation equipment, including (but not limited to) lathes, milling machines, a variety of welders, a band saw, workbenches, vices, a wide assortment of hand tools, a phototachometer, an extensometer, a shear test fixture, durometers, and hardness testers.

East Carolina University maintains and supports shared research facilities and services.Shared equipment available on ECU’s main campus includes an Accelerator Laboratory, Acoustic Laboratory, Biomedical Laser Laboratory, Biomedical Optics Laboratory, Genomics and Bioinformatics Laboratory, High Performance Computing Facility, Nuclear Magnetic Resonance Spectroscopy Laboratory and Mass Spectrometry Facility.

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The computing needs of biomedical engineering graduate students will be supported by the College of Technology and Computer Science (TECS), the High Performance Computing laboratory and Information Technology and Computing Services (ITCS). The laboratories listed above, and any office space, are equipped with the computers needed to perform data analysis or other research related tasks.

TECS provides an array of support including software, hardware, and technical services support. This includes the infrastructure to provide cluster computing and remote display of graphically intensive applications with VMware View and Vcloud Director. Technical services also support desktops on demand, virtual servers on demand and network attached storage space.

ITCS supports additional student computing needs through two unique services: High Performance Computing and the Virtual Computing Lab. The high performance computing capabilities offered by ITCS are optimized for solving some of the advanced computational problems that arise in engineering research. The Virtual Computing Lab, located at NC State University, provides remote access to a variety of advanced software packages. ITCS provides this access through ECU’s network.

Research facilities supported by the Brody School of Medicine include:Major laboratory equipment is available in the Brody Medical Sciences Building (3S-16, 400 sq. ft), including a laminar flow hood, chemical hood, three CO2 water-jacketed incubators, centrifuge with rotors, laboratory refrigerator and freezer; an inverted microscope, upright microscope and dissecting microscope; distilled water source, balance, and pH meter.

The Tissue Culture Facility located in the Warren Life Science Building (LSB 279, 800 sq ft), room 279, offers additional lab space. Major equipment includes three bench top work areas with adjacent laminar flow hoods, one chemical hood, two CO2 water-jacketed incubators, tabletop centrifuge with rotors, laboratory refrigerator, two laboratory freezers (-20° C, -80° C), a Dewar liquid nitrogen cell storage system, inverted and upright light microscopes, a digital camera with C-mount, and distilled water source. Additional equipment in this laboratory, i.e., syringe pump and high-voltage power supply (Gamma High Voltage Research), supports nano-electrospinning research.

The BSOM maintains Core Facilities to support campus-wide research efforts. These facilities include:

The Flow Cytometry-Confocal Microscopy Core Facility is a research support resource in the BSOM Biotechnology Program. This multi-user shared instrumentation resource is located on the 4th floor of the Brody Medical Science building. The facility has two bench top flow analyzers (Becton Dickinson FACScan), a four-color cell sorter, Becton Dickinson FACSVantage SE, with high-speed sorting capability, a polychromatic flow cytometry system, Becton Dickinson LSR II, and a Zeiss LSM 510 Laser-scanning Confocal Microscope coupled to an inverted (Axiovert) microscope.

Zeiss PALM Laser Capture Microdissection System. The PALM MicroBeam System is a non-contact sampling technique for medical and biological materials for recovery of DNA, RNA and protein. This system combines laser microdissection with a laser-assisted transfer. This multi-user shared instrumentation resource is located on the 3rd floor of the Brody Medical Science building.

Zeiss LSM 700 Laser-scanning Confocal Microscope coupled to an inverted (Axiovert) microscope and on stage incubation system for live cell and time-lapse imaging (new facility, 8/2013). This multi-user shared instrumentation resource is located on the 3rd floor of the Brody Medical Science building.

Phosphor-Imaging/Fluorescence Imaging (PhIFI) core facility houses a fully equipped Amersham/ GE Healthcare Typhoon 9410 Imager for 2D imaging of phosphorescent, chemiluminescent and fluorescent gel and array data. The Typhoon 9410 is capable of detecting, imaging and quantifying five different forms of emission: phosphor autoradiography, chemiluminescence, blue-excited fluorescence, green-excited fluorescence, and red-excited fluorescence.

Electron microscope laboratory with JEOL 1200EX TEM; CCD camera and Leica UC6 Ultramicrotome. Histology laboratory with Microm HM505E Cryostat, Microm HM340E digital advance rotary

microtome, Citadel 1000 Tissue Processor for paraffin embedding, and Sequenza Immunostaining System, to provide research support in histology and immunohistochemistry.

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Metabolomics laboratory, with LINCOplex 200, for protein expression profiling, gene expression profiling and diagnostics.

Additional shared resources include (but are not limited to) centrifuges, electrophoresis equipment, various imaging systems, chromatography systems, an ultrasound machine, microscopes, and spectrophotometers.

In the first few years after program start up, we will work with the Health Science Campus, Research and Graduate Studies and joint faculty to identify a specific plan for space and equipment. We plan to grow in collaboration with our key partners so space and equipment will be highly utilized.

● How will assignment of this space to the proposed program impact existing programs?The spaces proposed are currently available for use by all faculty and will not impact existing program utilization of the space.

● Describe additional facilities or specialized equipment that would be needed over the next five years.With the growth of the program additional office and laboratory space will be needed for new faculty members. The College of Technology and Computer Science has space available to accommodate graduate students on assistantships in the Science and Technology building.

● Describe current holdings in library resources in the proposed program and projected library resources needed to support the proposed program.

The J.Y. Joyner Library on east campus and William E. Laupus Health Sciences Library on west campus provide library resources and services to support the research, teaching, and service goals of East Carolina University. Joyner Library is the largest library on the ECU campus. Access Engineering is a currently subscribed database at Joyner Library and provides a rich collection of eBooks, videos, and other literature in the Bioengineering field. In addition, ECU Library Resources provides online access to tens of thousands of journals, reference materials, e-books, and databases. A unique library guide link for engineering has been established “Engineering: a guide to library resources”. This link provides faculty, students and staff with access to engineering resources, i.e. handbooks, journal articles, reference books, technical reports & patents and other valuable resource material. Current journal subscriptions and books are sufficient to start the proposed program including the Journal of Biomechanics, the Journal of Magnetic Resonance Imaging, Medical and Biological Engineering and Computing, several IEEE Transactions series, and the Journal of Neural Engineering. A few additional subscriptions (for example, Journal of Biomechanical Engineering) may need to be added over the first five years.

The William E. Laupus Health Sciences Library connects the education, research, and clinical programs of ECU’s Division of Health Sciences, Eastern Area Health Education Center (EAHEC), and health care practitioners in eastern North Carolina with quality health information. The Laupus Library serves the BSOM, the College of Nursing, the College of Allied Health Sciences, and the SODM. Library services are also extended to the region’s health care providers. The library delivers information services and resources to health providers at Vidant Medical Center in Greenville and Vidant Health System affiliates across eastern North Carolina. In 2006, Laupus Library moved to the new Health Sciences Building on ECU’s medical campus. The library shares this 300,000 square foot state-of-the-art educational center with the College of Allied Health Sciences and the College of Nursing. The four-story 72,000 square foot library provides study space, a computer lab, media production and consultation services, reference services, circulating and historical collections.

Laupus Library collects current information in the biomedical engineering subject area, mostly in electronic format to increase ease of use and access. Laupus library works with Joyner Library to ensure that all electronic holdings appear across all our shared resource platforms, so that medical and engineering-specific materials can be found regardless of which library is the student’s starting point. Laupus library also promotes and teaches classes on how to most efficiently use databases such as PubMed and Web of Science so that students can learn how to retrieve quality information.

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● Provide e-mail verification of consultation with Office of Space Management about the feasibility of new or additional space needs for the proposed program.

Please see attached email.

Personnel● What additional personnel would be needed to make the proposed program successful for growth and

development over a five-year period? Faculty – 1 additional position in Year 3 Two post-doctoral research associates One research technician Graduate assistants – 5 by Year 5 Other staff – 0.5 additional position to oversee graduate program paperwork

● What will be needed to recruit such individuals and what is the recruitment market like? To recruit the one additional faculty member a start-up package will be needed to attract highly qualified

individuals. In a recent faculty search conducted by the department of Engineering the department reviewed over 52 competitive biomedical engineering applicants and about 10 electrical engineering applicants with biomedical engineering expertise.

Graduate assistantships will be needed to attract quality graduate students. As biomedical engineering is a specialized field most industry jobs require at least an MS degree illustrating a high demand for the program.

Part Four: Assessing Financial Resources to Support the Program

● Describe existing financial resources to be devoted to the proposed program.The Department of Engineering currently has 24 FTE faculty positions, with ten of the current faculty supporting the undergraduate biomedical engineering concentration indirectly. Faculty resources are sufficient for initiation of the MS program.

● Describe what additional financial resources would be needed over the next five years and their proposed sources of funding.

Five graduate assistantships at $15,000 each One additional faculty member in Year 3 of the MS program One postdoctoral associate in Year 1 and one postdoctoral associate in Year 2 to support the research and

educational objectives of the program One research technician to oversee and support the research laboratories on the Health Science Campus

● What new financial resources will come to the university based on the projected increase in enrollment? At our projected enrollment of 25 MS students by year 5, taking 14 credits of engineering courses during

the course of their program, the additional student credit hours will justify one additional faculty position.

The engineering faculty supporting the proposed program have experience applying for, and receiving, external funding. The students will be involved in performance of externally-funded research programs (see Part Five: Assessing External Support and Collaboration), which will result in additional funding for faculty, funding for graduate student assistantships and generate indirect costs. Additional scholarship will also result from the program.

There is considerable potential for patents to result from the research and development conducted as part of this program. As an example, Dr. Jason Yao of Engineering and Dr. Greg Givens of Communication Sciences and Disorders have filed a patent for “Internet-based Multi-user Diagnostic Hearing Assessment Systems Having Client-server Architecture with User-based Access Levels for Secure Data Exchange,” provisional patent, 2009-2010; currently filing PCT (Patent Cooperation Treaty) to protect intellectual property rights worldwide. The university share of the royalties would generate financial resources.

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● Will the program students contribute to the financing of the program through teaching, research, and clinical practice?

The students will contribute by serving as teaching assistants in the undergraduate program and performing externally funded research (see Part Five: Assessing External Support and Collaboration).

● What are your plans for the program if the financial resources anticipated for the program (enrollment, external support, etc.) are 25% lower and 50% lower than expected?

Considering the current strength of the program and the growth in the related biomedical engineering jobs forecasted by the Bureau of Labor Statistics, a decline in program enrollment is unlikely. Current employment and labor projections in biomedical engineering related areas are very strong. If the decision was made to cut resources at the University or College level, possibly by denying the graduate assistantships or the additional faculty line in Year 3, the program would still be viable. Reduction of the number of assistantships would effectively reduce the “quality” of the students in the program since the best students would find assistantships at other universities and our program would be forced to admit students who are not able to find assistantships elsewhere. If the additional faculty position were refused, the projected size of the program might be reduced. In addition, the potential for research efforts in bioengineering would be reduced overall if faculty numbers were lower.

Part Five: Assessing External Support and Collaboration

● List of active grants/contracts specifically related to the proposed program.

Award No. TitleFaculty Member Sponsor Award

Core Biomedical Engineering Faculty

IIP-1256374

High speed low cost spectral domain optical coherence tomography system for intravascular imaging applications

Muller-Borer (Co-PI) NSF-SBIR $80,000

EphrinA1-Fc Attenuates Myocardial Infarct Injury

Muller-Borer (Consultant)

North Carolina Biotechnology

Center$75,000

Surgical Assessment of Bone Wax Material in a Porcine Model

Muller-Borer (Co-PI)

Pioneer Surgical Orthobiologics,

Inc.$8,332

R01-HL081720 

NO-independent cGMP regulation of vascular remodeling

Muller-Borer (Co investigator)

National Heart, Lung, and Blood

Institute$252,325

 Assessment of myocardial cellular transplantation via multiple delivery modes

Muller-Borer (Co-PI)

East Carolina Heart Institute $125,000

Heal the Hearing: from Combat to Reentry: as part of the ECU NC-Reentry Project.

Yao (PI) Department of Defense $89,989

Development of a Suite of Project Modules Related to Real World in an Instrumentation and Controls Course.

Yao (PI)

East Carolina University Faculty Senator Teaching

Grant

$10,000

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A10-0043-0001

Portable Cyber laboratories: Virtual Instruments and Affordable Prototyping Kits to Enhance Learning and Improve Access to Electrical Engineering Education

Yao (PI) National Science Foundation $88,100

Fleet Management Criteria: Depreciated Life, Disposal Point & Utilization

Yao (Co-PI)North Carolina Department of Transportation

$95,334

Development of a Location Identification Device for Orthopedic Infection (Phase II)

Yao (PI)ECU Office of

Technology Transfer

$1,500

Development of a Location Identification Device for Orthopedic Infection (Phase I)

Yao (PI)ECU Office of

Technology Transfer

$6,000

Development of a Web Services Based Distributed System for Tele-Hearing Diagnosis

Yao (PI) ECU College of Allied Health $25,000

A11-0048-001

Engineering photoreceptor-controlled aggregation and disaggregation of nanoparticles

Limberis (PI)North Carolina Biotechnology

Center$82,500

Non Invasive Transcranial Doppler Intracranial Hypertension Detection

Kim (Co-PI) UCLA

Upgrade and Save with Energy Star

Abdel-Salam (Co-PI)

North Carolina State Energy Office

$200,000

Greening Coastal Vacation Rental Properties Abdel-Salam (PI) EPA $30,000

● Describe existing collaborative efforts related to the proposed program with community or state agencies, other institutions of higher education, federal laboratories or agencies, national centers, or other external organizations.

The Department of Engineering maintains a collaborative relationship with the following industry partners, who are members of the Engineering Advisory Board (EAB):

East Carolina University Brody School of Medicine Vidant Health, Greenville, NC MX Biodevices, Greenville, NC RTI Biologics, Inc. (formerly Pioneer Surgical Orthobiologics, Inc.), Greenville, NC Metrics, Inc., Greenville, NC East Group, Greenville, NC Pitt County Development Commission, Greenville, NC DSM Pharmaceuticals, Greenville, NC DSM-Dyneema, LLC, Greenville, NC NAACO Materials Handling Group, Greenville, NC North Carolina’s Eastern Region, Kinston, NC BD Medical, Research Triangle Park, NC GSK, Inc., Research Triangle Park, NC Pharmaceutical Calibrations and Instrumentation, Raleigh, NC Triangle Biosystems, Durham, NC North Carolina Biotechnology Center, Research Triangle Park, NC

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Merck & Co., Inc., Wilson, NC Pfizer, Sanford, NC Covidien, Raleigh, NC PCS Phosphate, Aurora, NC Duke University Fuqua School of Business, Durham, NC NASA Langley Research Center, Hampton, VA Centers for Disease Control, Atlanta, GA

Strong liaisons have been established with ECU’s Department of Engineering and the EAB comprised of approximately 40 members from industry, consulting firms, academia, and government laboratories. This board meets twice during the year to review current and planned programs, review student achievement, and provide guidance on future directions of the program. The board is extremely active, and the department chair maintains contact with the board throughout the year. A new partner for 2011 included the Centers for Disease Control who sponsored a Senior Capstone Project. Vidant Health, a new partner in 2012, includes a network of 10 hospitals and 15 associated clinics in rural eastern NC. The faculty is continuously pursuing industry and government partners. A number of these organizations participate in the department’s senior capstone design project and provide student internships. Biomedical engineering capstone projects and sponsors since 2008 include:

“Development of a Tactile Input Device for Use in Balance Studies”, Leslie Allison, PhD, ECU, College of Allied Health Sciences, Department of Physical Therapy.

“Design of an Injection Trainer”, Dr. Ed Bartlett, Orthopaedics East, Greenville, NC. “Design of a Mechanical Labor and Delivery Bed for Low Resource Settings”, Center for Disease

Control, Atlanta, GA “Modulated Lighting of Approach/Avoidance Inclinations”, Dr. Alan Pope, National Aeronautics and

Space Administration, Langley Research Center, Hampton, VA. “Push-up Pal”, Matthew Mahar, PhD, ECU, College of Health and Human Performance, Department

of Kinesiology. “Plantar Flexion Device”, Timothy Gavin, PhD, ECU, College of Health and Human Performance,

Department of Kinesiology. “Development of the Structure and Steering of a Manual Mobility and Exercise Device: Citty

Stepper”, Mark Dumas, MD, Kinston, NC. “Limits of Stability Testing, Prototype Improvement/Redesign”, Leslie Allison, PhD, ECU, College

of Allied Health Sciences, Department of Physical Therapy. Electrical Stimulation Instrument for 2D and 3D Cell Culture”, Barbara J. Muller-Borer, PhD, ECU,

Departments of Engineering and Cardiovascular Sciences. “Development of an acoustic dust generator for rodent inhalation studies of nanomaterials”, Dianne

Walters, PhD, ECU, Brody School of Medicine, Department of Physiology.

In addition, students are encouraged to complete an internship or participate in a research laboratory experience. Examples of locations where students have completed internships include Hospira, Inc., Rocky Mount, NC, Pharmaceutical Calibration Incorporated, RTP, DSM and Pioneer Surgical Orthobiologics, Inc, Greenville, NC. Currently, undergraduate biomedical engineering students are actively participating in research projects in ECU laboratories in the:

Department of Engineering Department of Comparative Medicine School of Dental Medicine Department of Physiology Department of Cardiovascular Sciences Department of Kinesiology College of Nursing

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Drs. Griffin and Muller-Borer have met with Dean James Ryan, PhD, Joint School of Nanoscience and Nanoengineering (JSNN), former Chair Leonard Uitenham, PhD, and current Chair Stephen Knisley, PhD, Department of Chemical, Biological and Biomedical Engineering, NC A&T State University and Chair Nancy Allbritton, MD, PhD, UNC/NCSU Joint Department of Biomedical Engineering. An overview of the proposed Master of Science in Biomedical Engineering program was provided and opportunities for collaborations were discussed. Specific collaborative opportunities identified at these institutions include:

JSNN – Joint research, summer internships and access to unique equipment and laboratories in nanomaterials, nanobioelectronics and computational nanotechnology. Graduates of ECU’s MS program would be competitive for the PhD in Nanoengineering offered at the JSNN.

NC A&T State University - Graduate level courses in biomaterials available by synchronous broadcast via NC A&T State University, University of Pittsburgh and University of Cincinnati (NSF Engineering Research Center partners).

UNC/NCSU Joint Department of Biomedical Engineering – Synchronous broadcast of Biomedical Engineering seminar series to ECU. Facilitated admission to doctoral biomedical engineering program.

● How do you plan to use external funding to support the proposed program? To what agencies or programs would proposals be submitted and with what timeframe?

The following external agencies support academic biomedical engineering research, both nationally and regionally:

The National Institutes of Health. One of the stated goals of the NIH is to foster creative discoveries, innovative research strategies, and their applications as a basis for protecting and improving health. The NIH realizes this goal by supporting a wide range of research activities, through the 27 institutes and centers that comprise this federal organization. Specific institutes that are pertinent to the proposed program include the National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institute of Neurological Disorders and Stroke (NINDS), National Institute of General Medical Sciences (NIGMS), and the National Heart, Lung, and Blood Institute (NHLBI).

The NIH also funds research projects at less-established research universities through several grant mechanisms. One such mechanism is the Academic Research Enhancement Award (AREA) grant, which is specifically designed to stimulate biomedical research at institutions that provide baccalaureate and advanced degrees.

The National Science Foundation. A well-established federal agency created “to promote the progress of science; to advance the national health, prosperity and welfare; to secure the national defense…” This organization has a long-standing history as a major source of federal funding for a wide assortment of cutting-edge STEM research.

Department of Defense. The DOD provides a number of grant mechanisms through the Defense Advanced Research Projects Agency (DARPA), Office of Naval Research (ONR), Air Force Office of Scientific Research (OSR), and the Multidisciplinary University Research Initiative (MURI). A popular graduate fellowship program offered by the DOD, is the National Defense Science and Engineering Graduate Fellowship. This program provides three years of support for studies in biosciences, electrical engineering, and cognitive, neural, and behavioral sciences.

The North Carolina Biotechnology Center. The NC Biotech center is a state-funded, privately held non-profit organization dedicated entirely to biotechnology development. The mission of this center is to provide long-term economic and societal benefits to North Carolina by supporting biotechnology research, commercialization, collaboration, and education. The NCBC funds biotechnology research in areas such as nanobiotechnology and combination medical devices. The center also funds multidisciplinary research, for projects consisting of scientists from at least three distinct fields.

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The engineering faculty supporting the proposed program has experience applying for, and receiving, external funding from the above organizations. The stated goals of each grant agency, and the funding programs offered, align with the research background of the faculty. Specifically, the proposed biomedical engineering graduate program will foster research in the following areas: neural and cardiac electrophysiology, cardiac stem cell therapies, computational hemodynamics, blood flow analysis using MRI, medical imaging, and medical device design, MRI compatibility and biomedical signal analysis.

Research efforts in these areas are either ongoing through existing grants (listed above), or are in development. Faculty members in the proposed program are currently preparing competitive grant applications for initial submission in the 2013-2014 academic years. It is anticipated that external grant funding will provide graduate assistant support. Projects include:

Jason Yao, PhD, Associate Professor, Electrical Engineering, Department of Engineering PI, “Collaborative Research: Cyber-Physical Tools for the MOOC Age: Personalized Hands-On

Electrical Engineering Learning Experiences for Distributed Education”, $150,063. NSF-ECR program, 1/1/2014 – 12/31/2016.

PI , “Timely Assessment of Cochlear Integrity in Combat Theater,” Department of Defense, $259,158. pending.

Co-PI , “Cubesat ground station: NCER subcontract,” AgCarolina Financial $4,998.00. (PI: Eban Bean, PhD, ECU Department of Engineering) pending.

Barbara J. Muller-Borer, PhD, Associate Professor, Biomedical Engineering, Department of Engineering Collaborating Investigator , “Peroxisomal-Mitochondrial Interactions in Human Skeletal Muscle and

Obesity” National Institutes of Health RO1 (PI, Ron Cortright, PhD, ECU Department of Kinesiology) $1,465,450.000, in revision.

Co-PI , “Intramyocardial EphrinA1-Fc Reduces Acute Injury and Chronic Remodeling”. National Heart, Lung and Blood Institute R21, (PI: Jitka I. Virag, PhD, ECU Department of Physiology) $300,000, in revision.

Collaborating Investigator , “Pilot Study on Disparities of Peri-Partum Cardiomyopathy”, ECU Center for Health Disparities (PI, Long Cao, MD, ECU Department of Cardiovascular Sciences), $75,000, pending.

Stephanie M. George, PhD., Assistant Professor, Biomedical Engineering, Department of Engineering PI , “MR and Computational Analysis of the Pulmonary Artery and Right Ventricle in Pulmonary

Hypertension”, American Heart Association Beginning Grant-in-Aid Mid-Atlantic Affiliate, $153,115, pending.

PI , “Hemodynamic Investigation of Pulmonary Hypertension using MRI and CFD”, NIH Heart, Lung, and Blood Institute, $440,396, pending.

PI , “MR-Guided Differentiation of Pulmonary Hypertension in Sickle Cell Patients”, ECU Center for Health Disparities, $ 223,911, pending.

PI, “Biomedical Engineering in Simulations, Imaging, and Modeling (BME-SIM) “, NSF – REU, $360,000, pending

Ricky T. Castles, PhD, Assistant Professor, Electrical Engineering, Department of Engineering Collaborating Investigator , “ECU Connects! Expanding the STEM Pipeline through long-term

partnerships between schools and industry”. NSF Math Science Partnership Grant Program. $1,378,264, 36 months 2013-2016, pending.

PI, “Advancing Personalized Learning- Using Physiological Sensors to Evaluate the Effectiveness of Novel Instruction in Engineering Statics “, NSF – REU, $300,000, pending

It should be noted that, Dr. George and Dr. Castles are each preparing NSF-Research for Undergraduate proposals (August 2013 submission). It is anticipated that awarding of these programs will facilitate recruiting of competitive graduate students to this master of science program.

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As mentioned in the personnel requirements, the Master of Science in Biomedical Engineering program can be started with current faculty personnel and resources, however to initiate research momentum, funding for graduate assistants may be needed during the start-up period. This will allow for preliminary research to be conducted preparing the core engineering and collaborating faculty to compete for external funding.

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Faculty Information: Pgs

Odis Hayden Griffin, Jr., Ph.D., P.E 18 - 33

Barbara J. Muller-Borer, PhD 34 - 45

Jianchu (Jason) Yao, PhD 46 - 52

Loren Limberis, PhD 53 – 57

Stephanie M. George, PhD 58 – 61

Sunghan Kim, PhD 62 – 65

Tarek Abdel-Salam, PhD 66 – 75

Ricky T. Castles, PhD 76 – 80

Amanda K. Funai, PhD (new hire 8/2013, visiting assistant professor) 81 - 83

Zhen Zu, PhD (new hire 8/2013, teaching assistant professor) 84 - 87

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Faculty Information Sheet

Name: Odis Hayden Griffin, Jr., Ph.D., P.E.1. Rank: Professor and Chair, Department of Engineering at East Carolina University

2. Degrees: Virginia Polytechnic Institute & State University, Blacksburg, Virginia

Doctor of Philosophy in Engineering Mechanics, June, 1980. Course work primarily in area of solid mechanics. Dissertation “Three Dimensional Inelastic Finite Element Analysis of Laminated Composites.” Use of finite element method with a modified Hill-type yield criterion and flow rule to study interlaminar stresses in laminates subject to thermal and mechanical loading.

Texas Tech University, Lubbock, TexasMaster of Science in Mechanical Engineering, May 1971. Course work primarily in thermodynamics and heat transfer. Thesis, “A New Theory of Protoplasmic Streaming.” Application of nonequilibrium thermodynamic principles to living cells.

Bachelor of Science in Mechanical Engineering, August 1970. Course work in thermodynamics, heat transfer, machine design, fluid dynamics, strength of materials, and metallurgy.

3.Teaching Experience related to proposed degree (with emphasis on the past five years)Workload assignment: 15% teaching, 85% administrative

July 2010 to present, Professor and Chair, Department of Engineering, East Carolina University, Greenville, North Carolina 27858

Leading the faculty of the East Carolina University Department of Engineering. Serve as chief administrative officer, reporting to the Dean of the College, responsible for department’s resources, staff, and budgets. Provide leadership for the department in accomplishing departmental mission and setting and achieving goals. Promote excellence in teaching and advising, scholarship, research productivity, economic development, and professional service. Serve as principal advocate for the department within the College, serving on the Administrative Council. Ensure proper application of tenure and promotion policies set forth in the East Carolina University Faculty Manual. Conduct annual faculty activity planning and evaluation. Working to evaluate possible new concentrations in the BS in Engineering program and working with a faculty group to develop a MS in biomedical engineering degree program.

May 2004 – June 2010, Professor and Head, Department of Engineering Education (departmental name change), College of Engineering, Virginia Polytechnic Institute & State University, Blacksburg, Virginia 24061-0218

Planned and led changes in the department from a primarily teaching-only, freshman engineering program to a degree-granting, research-oriented department, increasing external research funding from near zero in 2003 to several million dollars at the present time, including three NSF CAREER Awards (Borrego, Paretti, and Johri) and one PECASE (Borrego). Added new faculty in the area of academic assessment, technical communications, engineering design, and learning sciences. Led and participated in research proposals in the area of engineering education. Diversified the faculty from all white males (1997) to a department in which half (9 of 18) of the faculty are women, with good ethnic and disciplinary diversity as well. Tenure outcomes for faculty hired since 1997 were good, and newer hires are progressing well toward tenure due to continuous attention to faculty development, assessment, and feedback.

Beginning in 2004, I led the effort to create a graduate program from scratch, culminating in a Ph.D. in Engineering Education, which accepted students in January 2008 and currently has 15 Ph.D. candidates. Have developed and taught or co-taught five new engineering education graduate courses: “Preparing for the Engineering Professoriate,” “Teaching Engineering,” “Practicum in the Engineering Classroom,” “Training System Design,” and “Foundations of Engineering Education.” Led the development of a

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Graduate Certificate in Engineering Education which is in place and has approximately 20 students participating. Presented the new courses and degree programs at all committees and commissions reviewing it for approval and also presented at the Board of Visitors and State Council of Higher Education for Virginia. Served as Graduate Program Director from January 2008 to February 2009. Presented information on engineering education and our graduate program to a Virginia General Assembly subcommittee considering creation of K-12 level standards of learning and other programs in Virginia public schools.

In 2006 my department was one of two university departments designated as a University Exemplary Department for developing and sustaining innovative and effective departmental approaches to introductory courses at the graduate and undergraduate levels. These awards are highly competitive and result in a $20,000 award to the department. As a group the faculty decided to spend the award on new office furniture as we moved into newly renovated space that I spent approximately two years working with the Provost and the Dean to obtain for the department. I am currently on the team that is providing design information for a new engineering building.

Worked with college development office personnel to gain gifts for laboratory renovation, facility maintenance, support for academic programs, and overall department support from both alumni and industry. Have obtained gifts in the form of cash, stock, hardware, and shop equipment.

Overall management of departmental budget of approximately $2M. In 11 years as department head, was never over budget, even though considerable resources were directed toward development of new courses, supporting the success of new faculty, creation of spaces for hands-on learning, and development of a PhD program. Department typically teaches 7,000-8,000 student credit hours annually.

Serving on the Program Assessment Committee of the Advisory Board for the University of Texas at El Paso College of Engineering. Regularly review papers for JEE, AEE, ASEE, ASME, iNEER. Served on NSF grant review panels twice for CCLI grants. Served on numerous College and University level committees. Most recently served on search committees for Director of Academic Assessment, Assistant Director of Academic Assessment, and Director of the Center for Excellence in Undergraduate Teaching. Served on the VT-Science Museum of Western Virginia Partnership Task Force and the Organizing Committee for the Governor’s Conference on STEM Education.

August 1997 – May 2004, Professor and Director, Division of Engineering Fundamentals (renamed as Department of Engineering Education in 2004), College of Engineering, Virginia Polytechnic Institute & State University, Blacksburg, Virginia 24061-0218

In addition to regular duties of a faculty member in the College of Engineering, oversee the efforts of the Engineering Fundamentals faculty and staff. The faculty currently has 14 members, including two part-time professional advisors. There are three full-time classified staff. Managing the Joseph F. Ware, Jr. Advanced Engineering Laboratory, an undergraduate student project laboratory with projects spanning numerous departments in the College of Engineering, Pamplin College of Business, and the College of Arts & Sciences. Leading the review and revision of the freshman engineering curriculum. Teaching courses in Engineering Fundamentals (problem solving, programming, introduction to design, and engineering graphics) and Mechanical Engineering (Advised Mini Baja Team, which is the capstone design project for some students, from August 1995 to May 2001).

Instituted policies for common syllabi, common tests, and common final exams in introductory engineering courses. Currently responsible for managing enrollments, assigning faculty teaching loads, and overseeing development of EF teaching schedule. Have encouraged, with success, EF faculty to write grant proposals, leading to several faculty who buy out of courses with project money. Scholarly production is also increasing steadily.

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July 1993 – August 1997, Associate Dean for Academic Affairs, College of Engineering, July 1994 – August 1997, Professor of Engineering Science & Mechanics, Virginia Polytechnic Institute & State University, Blacksburg, Virginia 24061-0217

In addition to regular duties of a faculty member in the College of Engineering, have responsibility for the undergraduate program of the College. Responsible for preparing ABET materials for College and coordinating departmental packages for Fall 1995 visit, with highly successful outcome. Serve on numerous College- and University-level task forces, commissions, and committees. Responsible for assembling departmental offerings for summer school and overseeing College summer school budget ($725K-$825K). Advise students on major changes, approve exceptions to University and College policies for undergraduates. Working on evaluation of curriculum and curriculum reform including course overlap between departments, cross-listing common courses. Chairing college-level committee assigned to review the undergraduate curriculum and revise from the beginning courses. Work with College Curriculum Committee for review of all proposed course modifications and inclusion of Engineering courses in the University Core Curriculum. Visit community colleges to recruit students, assist with in-house recruitment and retention programs. Proposed a new category for students wanting engineering who had previously been offered a general studies curriculum so that they are now students in Engineering and are able to take Engineering courses without difficulty. The first class of these students was admitted in the Fall 1994, and we are currently evaluating their performance. General response from students and parents has been overwhelmingly positive. Work with Admissions, Provost’s Office, Registrar’s Office, and other Associate Deans across the University in dealing with student admissions, appeals for academic exceptions, and resolving graduation problems.

During the period 1996-1998 I was the leader of the team that designed, oversaw the renovation, and directed the operations of the Joseph F. Ware, Jr. Advanced Engineering Laboratory. The Ware Lab, as it is popularly known, is one of a few such facilities in the country dedicated to undergraduate engineering projects. The Ware Lab (http://www.eng.vt.edu/warelab/) is a 10,000 square foot facility with a machine shop, welding shop, design studio, and work bays for student projects. Opened in September 1998, the Ware Lab has been a great success.

Courses taught include: ESM 1000, Statics; ESM 4044, Mechanics of Composite Materials; ESM 4734/AOE 4024, Introduction to the Finite Element Method; ESM 3074 (now 2074), Computational Methods; ESM 2004, Mechanics of Deformable Bodies; ESM 5184, Special Study (Scientific Visual Analysis); ESM 5734, Introduction to the Finite Element Method; ESM 6734, Finite Element Method; ME 4014, Design Studies in Mechanical Engineering (Mini-Baja car project); ME 4016, Engineering Design and Project (Mini-Baja car project); EF 1005, Introduction to Engineering. Have modernized several courses, including Computational Methods. To date have advised ten M.S. theses and seven Ph.D. dissertations.

September 1985 - June 1994, Associate Professor of Engineering Science & Mechanics, Virginia Polytechnic Institute & State University, Blacksburg, Virginia 24061-0219

Involved in teaching, advising students, and performing research in mechanics of composite materials. Primary research interests include development of analytical and design tools for composites, including laminates and textile composites. Current efforts include designing crashworthy composite airframe components, analysis techniques for textile composites, and developing design and analysis tools for smart, damage tolerant/compensating composite structural components.

Co-investigator, NASA-Virginia Tech Composites Program, an ongoing program with NASA Langley Research Center. Primary activity was with Impact Dynamics Branch, involving analytical and experimental work in the dynamic response and failure of composite frames such as those used in aircraft primary structures and with the Mechanics of Materials Branch, developing analytical models for predicting stiffness, strength, and residual strength in textile composites.

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Co-investigator of a University Research Initiative on mechanics of smart materials and structures, funded by the Army Research Office. Responsibility for developing models for designing active control mechanisms for detecting and preventing growth of delaminations in composite laminates.

Graduate student supervisory experience (theses/dissertations):10 M.S. (with thesis) graduates, 7 Ph.D. completed.

Mark D. Sensmeier (co-advised with E. R. Johnson of AOE), M.S. Thesis, “Static and Dynamic Large Deflection Response of Graphite-Epoxy Beams,” June, 1987.

Marco A. Vidussoni, M.S. Thesis, “Global-Local Finite Element Analysis of Laminated Composites,” July 1988.

Gajanan V. Gandhe, M.S. Thesis, “Impact Response of Interleaved Composite Materials,” November 1988.

Shih Y. Lin, M.S. Thesis, “Investigation of the Use of Composite Materials in Highway Bridge Deck Modules,” December 1988.

David E. Bowles, Ph.D., “Micromechanics Analysis of Space Simulated Thermal Deformations and Stresses in Continuous Fiber Reinforced Composites,” December, 1989.

Danniella M. Thompson, M.S. Thesis, “Two-Dimensional to Three-Dimensional Global/Local Finite Element Analysis of Laminated Composites in Compression,” May 1990.

Dong K. Shin (co-advised with Z. Gurdal of ESM), Ph.D., “Minimum-Weight Design of Symmetrically Laminated Composite Plates for Postbuckling Performance Under In-plane Compression Loads,” September 1990.

Nicole Breivik (co-advised with Z. Gurdal of ESM), M.S. Thesis, “Compression of Thick Laminated Composite Beams with Initial Impact-Like Damage,” February 1992.

David H. Mollenhauer, M.S. Thesis, “Induced Strain of Actuation of Surface Bonded and Embedded Piezoceramic Patches,” April 1992.

Seshu R. Yalamanchili (co-advised with M. W. Hyer of ESM), M.S. Thesis, “Response of Multiple Fastener Composite Joints: Numerical and Experimental Results,” May 1992.

Jae Lee (co-advised with Z. Gurdal of ESM), Ph.D., “Vibration, Buckling and Postbuckling of Laminated Composites with Delaminations,” May 1992.

Elissa E. Carapella (co-advised with M. W. Hyer of ESM), M.S. Thesis, “Micromechanics of Crenulated Fibers in Carbon/Carbon Composites,” October 1992.

Su-Yuen Hsu, Ph.D., “Finite Element Micromechanics Modeling of Inelastic Deformation of Unidirectionally Fiber-Reinforced Composites,” July 1992.

Lucie M. H. Parietti, M.S. Thesis, “Micromechanical Finite Element Model for Constitutive Elastoplastic Analysis of Unidirectional Fiber-Reinforced Composites,” August 1994.

Eduardo Moas, Jr., Ph.D., “Progressive Failure Analysis of Laminated Composite Structures,” April 1996.

Edward H. Glaessgen, Ph.D., “Modeling of Textile Based Composite Materials, June 1996. Mark D. Sensmeier, Ph.D., “Optimum Crashworthiness Design of Grid-Stiffened Composite

Fuselage Structures,” September 1996.Served on advisory committees of numerous students in Departments of Engineering Science and Mechanics, Aerospace and Ocean Engineering, Civil Engineering, and Mechanical Engineering. Served on the examining committee for one MS student in Technology Education. Serving on PhD committees of one student in Technology Education, one student in Computer Engineering, and several students in Engineering Education.

Recent and Current Graduate Student AdvisingServed on Ph.D. advisory committees of Jennifer Mullin (Ph.D., Engineering Education, Virginia Tech, May 2010) and Ricky Castles (Ph.D., Computer Engineering, Virginia Tech, May 2010). Currently serving on Ph.D. committee of Parhum Delgoshaei (Ph.D. Candidate, Engineering Education, Virginia Tech, anticipated completion May 2012).

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4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years):a. Publications/Scholarly Activity related to proposed degree:

Benson, Lisa, Kurt Becker, Hayden Griffin, and Karl Smith, 2010. “Engineering Education: Departments, Degrees and Directions,” International Journal of Engineering Education, Special Edition on Applications of Engineering Education Research, Vol 5.

Lohani, V., Castles, R., Lo, J., and Griffin, H., 2008. “Tablet PC Applications in a Large Engineering Program,” Computers in Education Journal, Vol XVIII, No. 1, April-June 2008, pp 52-63.

Snook, J., Lohani, V.K., Lo, J.L., Sirvole, K., Mullin, J.S., Kaeli, J.K., and Griffin, O.H., “Incorporation of a 3-D Interactive Graphics Programming Language into an Introductory Engineering Course,” Computers in Education Journal, Vol XVI, No. 3, July-September 2006, pp 63-72.

Lee, J., Gurdal, Z., and Griffin, O. H., Jr., “Buckling and Postbuckling of Circular Plates Containing Concentric Penny-Shaped Delaminations,” Computers & Structures, vol. 58, No. 5, 1996, pp. 1045-1054.

S. Y. Hsu and O. H. Griffin, Jr., “Algorithmic tangent matrix approach for mixed hardening model of endochronic plasticity,” Computer Methods in Applied Mechanics and Engineering, Vol 133, 1996, pp 1-14.

E. H. Glaessgen, C. M. Pastore, O. H. Griffin, Jr., and A. Birger, “Geometrical and finite element modeling of textile composites,” Composites: Part B, Vol 27B, No 1, 1996, pp 43-50.

E. H. Glaessgen and O. H. Griffin, Jr., “Micromechanical Analysis of Thermal Response in Textile-Based Composites,” AIAA Progress in Aeronautics and Astronautics, Earl A. Thornton, Editor, Volume 168, 1995, pp 204-217.

J. Lee, Z. Gurdal, and O. H. Griffin, Jr. “Postbuckling of Laminated Composites with Delaminations,” AIAA Journal, Vol 33, No 10, October 1995, pp 1963-1970.

D. Cohen, M. W. Hyer, O. H. Griffin, Jr., S. R. Yalamanchili, M. J. Shuart, and C. Prasad, “Failure Criterion for Thick Multi-Fastener Graphite-Epoxy Composite Joints,” Journal of Composites Technology and Research, Vol 17, No 3, 1995, pp 237-248.

L. M. Parietti, S. Y. Hsu, and O. H. Griffin, Jr., “Mini Constitutive Finite Element Model for Plastic Response of Unidirectional Fiber Composites,” Computers and Structures, Vol 55, No 3, May 1995, pp 463-470.

E. Moas, R. L. Boitnott, and O. H. Griffin, Jr., “An Analytical and Experimental Investigation of the Response of Curved, Composite Frame/Skin Specimens,” Journal of the American Helicopter Society, July, 1994, pp. 58-66.

J. Lee, R. T. Haftka, O. H. Griffin, Jr., L. T. Watson, and M. D. Sensmeier, “Detecting Delaminations in a Composite Beam using Anti-optimization,” Structural Optimization, Vol 8 (2/3), October 1994, pp 93-100.

E. E. Carapella, M. W. Hyer, O. H. Griffin, Jr., and H. G. Maahs, “Micromechanics of Crenulated Fibers,” Journal of Composite Materials, Vol 28, No 14, 1994, pp 1322-1346.

D. H. Mollenhauer and O. H. Griffin, Jr., “Induced Strain of Actuation of Surface Bonded Piezoceramic Patches: A Numerical and Experimental Study,” Journal of Intelligent Material Systems and Structures, Vol 5, No 3, May 1994, pp 355-362.

O. H. Griffin, Jr., M. W. Hyer, S. R. Yalamanchili, M. J. Shuart, C. B. Prasad and D. Cohen, “Analysis of Multi-Fastener Composite Joints,” Journal of Spacecraft and Rockets, Vol 31, No 2, March-April 1994, pp 278-284.

David H. Mollenhauer, Danniella Muheim Thompson, and O. Hayden Griffin, Jr., “Finite Element Analysis of Smart Structures,” Advances in Engineering Software, Vol 17, No 1, 1993, pp 7-12.

N. L. Breivik, Z. Gurdal, and O. H. Griffin, Jr., “Compression of Laminated Composite Beams with Initial Damage,” Journal of Reinforced Plastics and Composites, Vol 12, No 7, July 1993, pp 813-824.

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D. M. Thompson and O. H. Griffin, Jr., “Finite Element Predictions of Active Buckling Control of Stiffened Panels,” Journal of Intelligent Material Systems and Structures, Vol 4, No 2, April, 1993, pp 243-247.

O. H. Griffin, Jr., E. R. Johnson, and M. D. Sensmeier, “Nonlinear Response of Graphite-Epoxy Wide Columns Subject to Eccentric Load,” Journal of Applied Mechanics, Vol 60, No 1, March 1993, pp 101-108.

D. K. Shin, O. H. Griffin, Jr., and Z. Gurdal, “Postbuckling Response of Laminated Plates Under Uniaxial Compression,” International Journal of Nonlinear Mechanics, Vol 28, No 1, Jan 1993, pp 95-115.

S. Y. Hsu and O. H. Griffin, Jr., “On Stability and Efficiency of Numerical Integration of Endochronic Constitutive Equations,” Computers and Structures, Vol. 44, No. 3, 1992, pp 657-665.

D. M. Thompson and O. H. Griffin, Jr., “Verification of a 2-D to 3-D Global/Local Finite Element Method for Symmetric Laminates,” Journal of Reinforced Plastics and Composites, Vol 11, No 8, August 1992, pp 910-931.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “Minimum-Weight Design of Laminated Composite Plates for Postbuckling Performance,” Applied Mechanics Reviews, Vol 44, No 11, part 2, Nov 1991, pp S219-S231.

D. E. Bowles and O. H. Griffin, Jr. “Micromechanics Analysis of Space Simulated Thermal Stresses in Composites. Part II: Multidirectional Laminates and Failure Predictions,” Journal of Reinforced Plastics and Composites, Vol 10, No 5, September 1991, pp 522-539.

D. E. Bowles and O. H. Griffin, Jr. “Micromechanics Analysis of Space Simulated Thermal Stresses in Composites. Part I: Theory and Unidirectional Laminates,” Journal of Reinforced Plastics and Composites, Vol 10, No 5, September 1991, pp 504-521.

N. F. Knight, Jr., J. B. Ransom, O. H. Griffin, Jr., and D. Muheim Thompson, “Global/Local Methods Research Using a Common Structural Analysis Framework,” Finite Elements in Analysis and Design, Vol 9, No 2, June 1991, pp 91-112.

S. S. Lane, R. H. Moore, H. P. Groger, G. V. Gandhe, and O. H. Griffin, Jr., “Eddy Current Inspection of Graphite/Epoxy Laminates,” Journal of Reinforced Plastics and Composites, Vol 10, No 2, March 1991, pp 158-166.

S. Y. Hsu, S. K. Jain, and O. Hayden Griffin, Jr., “Verification of Endochronic Theory for Nonproportional Loading Paths,” ASCE Journal of Engineering Mechanics, Vol 117, No 1, January 1991, pp 110-131.

D. Muheim Thompson, O. H. Griffin, Jr., and M. A. Vidussoni, “Global/Local Finite Element Analysis of Cross-Ply Composite Laminates,” Journal of Composites Technology and Research, Vol 12, No 4, December 1990, pp 209-216.

D. Muheim Thompson and O. H. Griffin, Jr., “2-D to 3-D Global/Local Finite Element Analysis of Cross-ply Composite Laminates,” Journal of Reinforced Plastics and Composites, Vol 9, No 5, September 1990, pp 492-502.

J. L. Sevart, O. H. Griffin, Jr., Z. Gurdal, and G. A. Warner, “Flammability and Toxicity of Composite Materials for Marine Vehicles,” Naval Engineers Journal, Vol 102, No 4, September, 1990, pp 45-54.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “A Penalty Approach for Nonlinear Optimization with Discrete Design Variables,” Engineering Optimization, Vol 16, No 1, July, 1990, pp 29-42.

G. V. Gandhe and O. H. Griffin, Jr., “Post-Impact Characterization of Interleaved Composite Materials,” SAMPE Quarterly, Vol 20, No 4, July 1989, pp 55-58.

Mark D. Sensmeier, O. Hayden Griffin, Jr., and Eric R. Johnson, “Effect of Axial Impact on the Static Flexure of Graphite/Epoxy Beams,” Journal of Reinforced Plastics and Composites, Vol 8, No 3, May 1989, pp 299-309.

O. Hayden Griffin, Jr., “Three Dimensional Thermal Stresses in Angle-Ply Composite Laminates,” Journal of Composite Materials, Vol 22, No 1, January 1988, pp 53-70.

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O. H. Griffin, Jr., “The Use of Proper Shear Moduli in the Analysis of Composite Materials,” Composites Technology Review, Vol 6, No 1, Spring 1984, pp 22-24.

O. H. Griffin, Jr. and J. C. Roberts, “Numerical/Experimental Correlation of Three Dimensional Thermal Stress Distributions in Graphite/Epoxy Laminates,” Journal of Composite Materials, Vol 17, Nov 1983, pp 539-548.

J. C. Roberts and O. H. Griffin, Jr., “Numerical/Experimental Heat Transfer in Dry Sliding of Polymeric Composites,” ASLE Transactions, Vol 26, No 4, 1983, pp 493-500.

O. H. Griffin, Jr. “Three Dimensional Curing Stresses in Symmetric Cross-ply Laminates with Temperature Dependent Properties,” Journal of Composite Materials, Vol 17, Sept 1983, pp 449-463.

O. H. Griffin, Jr. and C. R. Wilson, “Finite Element Analysis on a Microprocessor Based Personal Workstation,” Computers and Structures, Vol 17, No 4, 1983, pp 617-619.

O. H. Griffin, Jr., “Evaluation of Finite Element Software Packages for Stress Analysis of Laminated Composites,” Composites Technology Review, Vol 4, No 4, Winter 1982, p 136.

O. H. Griffin, Jr., M. P. Kamat, and C. T. Herakovich, “Three Dimensional Inelastic Finite Element Analysis of Laminated Composites,” Journal of Composite Materials, Vol 15, Nov 1981, pp 543-560.

b. Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners): “A National Symposium to Develop and Present a Case for the Establishment of Engineering

Education Academic Programs (SEEAP),” NSF Engineering Education and Centers unsolicited proposal, Kurt Becker (Utah State), Kamyar Haghighi (Purdue), Esin Gulari (Clemson), Hayden Griffin (Virginia Tech), ($99,548 for 1 year)

“Building Connections Within the Engineering Education Research Community,” NSF Engineering Education and Centers unsolicited proposal, Hayden Griffin (PI), Lisa McNair, Jenny Lo, Lisa McNair, and Marie Paretti ($153,691 for 1 year)

“Building Connections Within the Engineering Education Research Community,” NSF Engineering Education and Centers unsolicited proposal, Hayden Griffin (PI), Lisa McNair, Marie Paretti, Aditya Johri, and Christopher Williams ($307,468 for 2 years)

“International Network for Engineering Studies Workshop #1: Engineers and Education,”, NSF Office of International Science & Engineering, Gary Downey, Joe Pitt, Hayden Griffin ($32,820)

In 1993-94, I was the Principal Investigator at VPI&SU of SUCCEED Coalition, an eight-university consortium funded by NSF to conduct engineering education research. As a part of this research, I was responsible for monitoring all of the VPI&SU projects, control of the $100,000 plus administrative budget, and had authority and responsibility for determination of how to use the six FTE’s (approximate value $330,000 per year) associated with SUCCEED. I passed the SUCCEED responsibility along to an assistant dean because the demands on my time were too much considering my responsibilities to the undergraduate program.

“Bridges for Engineering Education – Virginia Tech,” $100,000, National Science Foundation, 8/1/2004 – 7/31/2006. One of many faculty involved.

“The NASA-Virginia Tech Composites Program”NASA Langley Research Center1974 - 1997Total funding - 1986 - 1997 - $4,300,000 (approximate)Principal investigators:O. H. Griffin, Jr., Z. Gurdal, M. W. Hyer, E. R. Johnson, A. C. Loos, D. H. Morris

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My share of the responsibility was for planning and conducting a portion of the work done with the Landing and Impact Dynamics Branch, Mechanics of Materials Branch, Aircraft Structures Branch, and the Applied Materials Branch. In addition, I worked with the Program Director one year in reviewing student applications, and was involved in the management of the Program during the year when we had an Interim Director.My share of the project funding is as follows:1985 - 1986: $11,000, 1986 - 1987: $50,000, 1987 - 1988: $48,500, 1989: $58,500, 1990: $46,000, 1991: $108,000, 1992: $138,035, 1993: $104,895, 1994: $95,000, 1995: $50,000My portion of funding, 1985 - 1995 was $709,930.

“Smart Materials, Structures and Mathematical Issues for Active Damage Control”Army Research Office University Research InitiativeTotal funding - $400,000July 1, 1992 - June 30, 1994 (years 1 and 2 of three years)Principal Investigators: C. A. Rogers, H. H. Robertshaw, R. T. Haftka, and O. Hayden Griffin, Jr.The responsibility was equally divided between the four investigatorsMy share of the project funding for 92-93 was $100,000 ($79,909 directly, plus $20,091 in educational and visiting scholar programs) and for 93-94 was $65,000.

“Development and Verification of Global/Local Analysis Techniques for Laminated Composites”NASA Langley Research CenterJune 16, 1986 - December 31, 1992Total funding - $183,194I was totally responsible for this project. The total funding, $183,194, was my responsibility.

“Thick Composite Joint Failure Analysis”Hercules Aerospace CompanyTotal funding - $70,048April 20, 1989 - December 31, 1991Principal Investigators: M. W. Hyer and O. Hayden Griffin, Jr.The responsibility of this project was equally divided between myself and Dr. Hyer.My share of the project funding was $35,024.

“Design of Stiffened Composite Plates for Postbuckling Performance”Newport News Shipbuilding & Dry Dock CompanyOctober 7, 1988 - September 30,1990Total funding - $40,052 (plus 70% overhead returned to project)Principal Investigators: Z. Gurdal and O. Hayden Griffin, Jr.The responsibility of this project is equally divided between myself and Dr. GurdalMy share of the project funding was $20,026.

“Virginia Institute for Material Systems”Commonwealth of VirginiaJuly 1, 1988 - July 1, 1990Total funding 1988-89 - $353,208, 1989-1990 - $518,061, 1990-1991 - $487,871, 1991-1992 - $479,563 (excluding overhead)Principal Investigators: J. McGrath, K. L. Reifsnider, G. Wilkes, T. Ward, W. W. Stinchcomb, A. C. Loos, H. F. Brinson, O. H. Griffin, Jr., D. Baird.My share of the responsibility has been to serve as an Associate Director of VIMS and conduct research into the mechanical behavior of composite materials.My share of the project funding was: 1988-89 - $34,000, 1989-90 - $40,000, 1990-91 - $30,000, 1991-92 - $35,000, 1992-93, $18,843, 1993-94, $17,000 ($174,843 total).

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“Automated Design of Composite Plates for Marine Applications”Virginia Center for Innovative Technology / Institute of Material Science and EngineeringNov 20, 1987 - Nov 19, 1988Total Funding - $34,543Principal Investigators: Z. Gurdal and O. Hayden Griffin, Jr.The responsibility of this project was equally divided between myself and Dr. GurdalMy share of the project funding was $17,271.

“Design of Composite Plates for Marine Vehicles”Newport News Shipbuilding & Dry Dock CompanyNov 20, 1987 - Nov 19, 1988Total funding - $37,997Principal Investigators: Z. Gurdal and O. Hayden Griffin, Jr.The responsibility of this project was equally divided between myself and Dr. GurdalMy share of the project funding was $18,998.

“Application of Composite Materials to Rail Transit Systems”NASA Langley Research Center and U.S. Department of TransportationMay 1, 1986 - April 30, 1987Total funding - $39,998Principal Investigators: C. T. Herakovich, O. H. Griffin, Jr., and Z. Gurdal.My portion of the project was to conduct a survey of the current uses and near-term planned uses of composite materials in urban mass transit systems. I also took the lead in writing the final report to the sponsors.My share of the funding was $18,000.

c. Invited research presentations outside ECU: Griffin, H., “Capturing Recent and Near Future Advances in Engineering Education,” Invited

presentation at The Ohio State University, January 2008. Griffin, H., “Innovation, Research, and Outreach in Engineering Education,” Invited presentation at

The Ohio State University, September 2007. Lohani, V. and Griffin, H., “A New Department of Engineering Education- Accomplishments in First

Year and Near-Term Goals,” Invited paper, International Conference on Engineering Education (iCEE 05), Gliwice, Poland, July 25-29, 2005.

Muffo, J., Lohani, V.K., Mullin, J., Backert, R., and Griffin, H., 2005, ‘From Engineering Fundamentals to Engineering Education –What’s in a Name?’, Invited Paper, International Conference on Engineering Education, February 28-March 5, 2005, Tainan, Taiwan.

Aning, A. O., Lohani, V.K., Griffin, H., Kampe, J.C.M., and Aref, H., ‘An Interdisciplinary Graduate Program in Engineering Education,’ Invited Paper, International Conference on Engineering Education, February 28-March 5, 2005, Tainan, Taiwan.

O. Hayden Griffin, Jr., “The Virginia Tech Department of Engineering Education: Present and Future,” presented at Purdue University, May 3, 2004.

O. H. Griffin, Jr., “Computational Structural Mechanics Needs Assessment,” presented at the Computational Structural Mechanics Branch Grant Review, October 23-24, 1991, NASA Langley Research Center, Hampton, Virginia.

O. H. Griffin, Jr., “Computational Mechanics Applied to Modern Materials and Structures,” invited lecture at the National Center for Supercomputing Applications, The Beckman Institute, University of Illinois, July 25, 1991.

O. H. Griffin, Jr. and D. M. Thompson, “2-D to 3-D Global/Local Finite Element Analysis of Laminated Composites,” invited presentation at the First U. S. National Congress on Computational Mechanics, Chicago, July 21-24, 1991.

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O. H. Griffin, Jr., “The Use of Computers in the Evaluation of Three Dimensional Stress Effects in Composite Materials Products,” invited Keynote Address, presented at the Second International Conference on Computer Aided Design in Composite Material Technology, Brussels, Belgium, April 25-27, 1990, pp 171-187.

O. H. Griffin, Jr., “Development and Verification of Local/Global Analysis Techniques for Laminated Composites II,” invited presentation at the LaRC Grant Review/ACT Review, NASA Langley Research Center, Hampton, Virginia, May 16-19, 1989.

O. H. Griffin, Jr., “Development and Verification of Local/Global Analysis Techniques for Laminated Composites I,” invited presentation at the NASA Workshop on Computational Structural Mechanics, NASA Langley Research Center, Hampton, Virginia, 18-20 November, 1987, NASA Conference Proceeding 10012, N. P. Sykes, Editor, February 1989, pp 683-732.

d. Chapters of Books, Editor of Proceedings, Instructional Movies, Manuals Wrote article on “Composites” for Encyclopedia of Science and Technology, 1998. Wrote articles on “Simple Machines,” “Lever,” “Wheel and Axle,” “Pulley,” “Inclined Plane,” for

1998 and 1999 versions of Microsoft Encarta electronic encyclopedia. Computer Aided Design in Composite Material Technology III, S. G. Advani, W. R. Blain, W. P. de

Wilde, J. W. Gillespie, and O. H. Griffin, Jr., Editors, Computational Mechanics Publications and Elsevier Applied Science, Publishers, 1992.

e. Refereed Papers Presented at Major International or National Technical Meetings Prashanth Jayaraman, Vinod Lohani, Garrett Bradley, Hayden Griffin, and John Dooley 2008.

“Enhancement of an Engineering Curriculum Through International Experiences,” Proceedings of the 2008 ASEE Annual Conference and Exposition, Pittsburgh, PA, June 22-25, 2008.

Vinod Lohani, Ricky Castles, Jenny Lo, and Hayden Griffin, 2007. “Tablet PC Applications in a Large Engineering Program,” Proceedings of the 2007 ASEE Annual Conference and Exposition, Honolulu, HI, June 24-27, 2007.

Odis Hayden Griffin, Jr. and Susan Cortes, “A Learning Space Of, By, And For Engineers: Virginia Tech’s Joseph F. Ware, Jr. Advanced Engineering Laboratory,” Paper DETC2006-99205, Proceedings of IDETC/CIE 2006: 3rd Symposium on International Design and Design Education, September 10-13, 2006, Philadelphia, Pennsylvania

Jennifer Mullin, Hayden Griffin, Jenny Lo, Vinod Lohani, “Co-teaching a Freshman Engineering Course: A Collaboration Between Experienced Faculty and Novice Graduate Students,” 2006 ASEE Conference, Chicago, June 19-21, 2006

Sharnnia Artis, Glenda Scales, Hayden Griffin, “From the Classroom to the Boardroom: The Use of Role Play in Graduate Education,” 2006 ASEE Conference, Chicago, June 19-21, 2006

Jenny Lo, Vinod Lohani, Hayden Griffin, “Full Implementation of a New Format for Freshman Engineering Course at Virginia Tech,” 2006 ASEE Conference, Chicago, June 19-21, 2006

Jennifer Mullin, Hayden Griffin, Jenny Lo, Vinod Lohani, “Sustainable Development Design Projects for Engineering Freshmen,” 2006 ASEE Conference, Chicago, June 19-21, 2006.

Lohani, V. K., Lo, J., Mullin, J., Muffo, J., Backert, R., and Griffin, H., 2005. “Transformation of a Freshman Year Engineering Course,” International Conference on Engineering Education, July 25-29, 2005, Gilwice, Poland.

Lohani, V. K., Wildman, T., Connor, J., Mallikarjunan, K., Wolfe, M. L., Muffo, J., Knott, T.W., Lo, J., Loganathan, G.V., Goff, R., Gregg, M., Chang, M., Cundiff, J., Adel, G., Agblevor, F., Vaughan, D., Fox, E., Griffin, H., Mostaghimi, S., 2005. “Spiral Curriculum Approach to Reformulate Engineering Curriculum,” Work-in-progress paper, Frontiers in Education Conference, Indianapolis, IN, 18-21 October 2005.

Griffin, O. H. and T. Walker, “Faculty and Student Response to a Laptop Computer Requirement for Engineering Freshmen,” 2005 ASEE Annual Conference, Portland, Oregon.

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Griffin, H., Aning, A., Lohani, V.K., Kampe, J., Goff, R., Paretti, M., Alley, M., Lo, J., Terpenny, J., Walker, T., Aref, H., Magliaro, S., and Sanders, M. 2005. “Designing and Implementing Graduate Programs in Engineering Education.” 2005 ASEE Annual Conference, Portland, Oregon.

Lo, J., Goff, R., Lohani, V., Walker, T., Knott, T., and Griffin, H., 2005. “New Paradigm for Foundational Engineering Education.” 2005 ASEE Annual Conference, Portland, Oregon.

Knott, M., Lohani, V.K., Griffin, H., Loganathan, G.V., Adel, G., Paretti, M., Wolfe, M., Mallikajunan, K., and Wildman, T., 2005, “Using e-portfolios in a large engineering program.” 2005 ASEE Annual Conference, Portland, Oregon.

Snook, J., Lohani, V.K., Lo, J., Sirvole, K., Mullins, J., Kaeli, J., and Griffin, H., 2005. “Incorporation of a 3-D Interactive Graphics Programming Language into an Introductory Engineering Course.” 2005 ASEE Annual Conference, Portland, Oregon.

Lohani, V.K., Sanders, M., Wildman, T., Connor, J., Mallikarjunan, K., Dillaha, T., Muffo, J., Knott, T.W., Lo, J., Loganathan, G.V., Adel, G., Wolfe, M.L., Goff, R., Gregg, M., Chang, M., Agblevor, F., Vaughan, D., Cundiff, J., Fox, E., Griffin, H., and Magliaro, S., 2005, “From BEEVT to DLR NSF Supported Engineering Education Projects at Virginia Tech,” 2005 ASEE Annual Conference, June 12-15, Portland, Oregon.

O. Hayden Griffin, Jr., Edward A. Fox, Calvin J. Ribbens, Thomas D. L. Walker, Nathaniel J. Davis IV, Richard M. Goff, Jenny L. Lo, Vinod K. Lohani, Michael H. Gregg, and Dwight Barnette, “Work in Progress – A Freshman Course for Engineering and Computer Science Students,” presented at the IEEE/ASEE Frontiers in Education Conference, October 2004, Savannah, GA.

Snook, J.S., Lohani, V. K., Lo, J., Sirvole, K., Mullins, J., Kaeli, J., Griffin, H. 2005 “Use of a Graphical Programming Language in an Introductory Engineering Course.” Poster presented at ACM SIGCSE 2005, St. Louis, MO, February 23-27, 2005.

Lohani, V. K., Sanders, M., Knott, T., Griffin, H., Bull, E., McIntyre, S., Connor, J., Loganathan, G. V., Wildman, T., Adel, G., and Magliaro, S. 2004, “Engineering-Education Collaboration - Virginia Tech,” Proc. Int. Conference on Engineering Education, Gainesville, FL. Oct. 2004.

O. H. Griffin, Jr., “Hands On, 24/7 – Virginia Tech’s Joseph F. Ware Jr. Advanced Engineering Laboratory,” Proceedings of the 2004 ASEE Conference, Salt Lake City, UT.

J.B. Connor, V.K. Lohani, E. Bull, T.M. Wildman, S.G. Magliaro, T.W. Knott, O.H. Griffin, Jr, and J.A. Muffo, “An Analysis of Freshman Engineering: A Cross-College Perspective”, Proceedings of the 2004 ASEE Conference, Salt Lake City, UT.

T. W. Knott, V. K. Lohani, O.H. Griffin, Jr., G.V. Loganathan, G. T. , Adel, and T. M. Wildman, “Bridges for Engineering Education: Exploring ePortfolios in Engineering Education at Virginia Tech”, Proceedings of the 2004 ASEE Conference, Salt Lake City, UT.

E. Moas and O.H. Griffin, Jr., “Progressive Failure Analysis of Laminated Composite Structures,” 37th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials (SDM) Conference, April 1996, pp 2246-2256.

M. D. Sensmeier, P. K. Sensharma, R. T. Haftka, O. H. Griffin, Jr., and L. T. Watson, “Experimental Validation of Anti-optimization Approach for Detecting Delamination Damage,” Proceedings of the 36th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials (SDM) Conference, New Orleans, LA, April 1995, p 3717.

E.H. Glaessgen and O. H. Griffin, Jr., “Effect of Applied Boundary Condition on the Analysis of Composites Based on Woven Preforms,” Proceedings of the 36th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials (SDM) Conference, New Orleans, LA, April 1995, p 38.

D. Cohen, M. W. Hyer, O. H. Griffin, Jr., S. R. Yalamanchili, M. J. Shuart, and C. Prasad, “Strength Predictions for Thick Multi-Fastener Graphite-Epoxy Composite Joints,” ASTM Symposium on Bolted and Bonded Joints in Composite Materials, November 16-17, 1993, Fort Worth, Texas.

J. Lee, O. H. Griffin, Jr., and Z. Gurdal, “Postbuckling of Laminated Composites with Delaminations,” presented at the AIAA/ASME/ASCE/AHS/ASC 34th Structures, Structural Dynamics, and Materials Conference, La Jolla, California, April 1993.

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E. E. Carapella, M. W. Hyer, and O. H. Griffin, Jr., “Micromechanics of Noncircular Fibers,” presented at the American Society for Composites 7th Technical Conference on Composite Materials, State College, PA, October 1992.

N. L. Breivik, Z. Gurdal, and O. H. Griffin, Jr., “Compression of Laminated Composite Beams with Initial Damage,” presented at the American Society for Composites 7th Technical Conference on Composite Materials, State College, PA, October 1992.

D. Cohen, L. Q. Do, M. W. Hyer, O. H. Griffin, S. R. Yalamanchili, M. J. Shuart, and C. B. Prasad, “Failure Criterion for Thick Multi-Fastener Graphite/Epoxy Composite Joints,” Proceedings of the 6th Japan-U.S. Conference on Composite Materials, Orlando, Florida, 22-24 June, 1992.

Danniella Muheim Thompson, David H. Mollenhauer, O. Hayden Griffin, Jr., “Finite Element Analysis of Smart Structures,” in Computer Aided Design in Composite Material Technology III, S. G. Advani, W. R. Blain, W. P. de Wilde, J. W. Gillespie, and O. H. Griffin, Jr., Editors, Computational Mechanics Publications and Elsevier Applied Science, Publishers, 1992, pp 419-429.

D. M. Thompson and O. H. Griffin, Jr., “Finite Element Predictions of Active Buckling Control of Stiffened Panels,” Proceedings of the Conference on Recent Advances in Adaptive and Sensory Materials, Blacksburg, Virginia, April 27-29, 1992, pp 377-384.

O. H. Griffin, Jr., M. W. Hyer, S. R. Yalamanchili, M. J. Shuart, C. B. Prasad and D. Cohen, “Analysis of MultiFastener Composite Joints,” Proceedings of the AIAA/ASME/ASCE/AHS/ASC 33rd Structures, Structural Dynamics, and Materials Conference, Dallas, April 13-15, 1992, pp 745-753.

J. Lee, Z. Gurdal, and O. H. Griffin, Jr., “A Layer-wise Approach for the Bifurcation Problem in Laminated Composites with Delaminations,” Proceedings of the AIAA/ASME/ASCE/AHS/ASC 33rd Structures, Structural Dynamics, and Materials Conference, Dallas, April 13-15, 1992, pp 10-20.

E. Moas, R. L. Boitnott, and O. H. Griffin, “An Experimental and Analytical Investigation of the Failure of Gr/Ep Composite I-Frames,” Proceedings of the 1991 American Helicopter Society (AHS) National Technical Specialists’ Meeting on Rotorcraft Structures Technology for the 1990’s and Beyond, Williamsburg, VA, October 28-31, 1991.

D. M. Thompson and O. H. Griffin, Jr., “2-D to 3-D Global/Local Finite Element Analysis of Symmetric Composite Laminates with Holes,” Proceedings of the Thirteenth Canadian Congress of Applied Mechanics, University of Manitoba, Winnipeg, Manitoba, June 2 - June 6, 1991, pp 200-201.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “Minimum Weight Design of Composite Plates for Postbuckling Performance,” Proceedings of the AIAA/ASME/ASCE/AHS/ASC 32nd Structures, Structural Dynamics, and Materials Conference, April 8-10, 1991, Baltimore, Maryland, pp 257-267.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “Minimum Weight Design of Laminated Composite Plates for Postbuckling Performance,” Proceedings of the Second Pan American Congress of Applied Mechanics, Vina del Mar, Chile, January 1991, pp 580-583.

O. H. Griffin, Jr., “The Use of Computers in the Evaluation of Three Dimensional Stress Effects in Composite Materials Products,” invited Keynote Address, in Composite Materials Design and Analysis, Proceedings of the Second International Conference on Computer Aided Design in Composite Material Technology, Brussels, Belgium, April 25-27, 1990, Springer Verlag, New York, pp 171-187.

D. M. Thompson and O. H. Griffin, Jr., “2-D to 3-D Global/Local Finite Element Analysis of Composite Laminates,” Proceedings of the 4th Technical Conference of the American Society for Composites, Blacksburg, Virginia, October 3-6, 1989.

S. S. Lane, R. H. Moore, G. V. Gandhe, and O. H. Griffin, Jr., “Eddy Current Inspection of Graphite/Epoxy Laminates,” Proceedings of the 4th Technical Conference of the American Society for Composites, Blacksburg, Virginia, October 3-6, 1989.

D. E. Bowles and O. H. Griffin, Jr., “Analysis of Thermal Stresses in Polymer Matrix Composites,” Proceedings of the 34th International SAMPE Symposium, Reno, Nevada, May 8-11, 1989.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “A Penalty Approach for Nonlinear Optimization with Discrete Design Variables,” Proceedings of the Association for Applied Mathematics and Mechanics

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(GAMM) Seminar on Discretization Methods and Structural Optimization - Procedures and Applications, University of Siegen, Federal Republic of Germany, October 3-5, 1988.

D. K. Shin, Z. Gurdal, and O. H. Griffin, Jr., “A Penalty Approach for Nonlinear Optimization with Discrete Design Variables,” Proceedings of the Second NASA/Air Force Symposium on Recent Advances in Multidisciplinary Analysis and Optimization, September 28-30, 1988, Hampton, Virginia.

O. H. Griffin, Jr. and M. A. Vidussoni, “Local/Global Finite Element Analysis of Composite Materials,” in Computer Aided Design in Composite Material Technology, Proceedings of the International Symposium, Southampton, UK, April 13-15, 1988, C. A. Brebbia, W. P. de Wilde, and W. R. Blain, Editors, Springer-Verlag, 1988, pp 513-524.

M. D. Sensmeier, O. H. Griffin, Jr., and E. R. Johnson, “Effect of Axial Impact on the Static Flexure of Graphite/Epoxy Beams,” Proceedings of the Joint ASC/CCM Symposium on Composites Science and Engineering, University of Delaware, Newark, DE, September 1987.

C. R. Wilson and O. H. Griffin, Jr., “An Integrated Multi-computer Network for a Research Center,” Proceedings of the 1983 ASME International Computers in Engineering Conference, Chicago, August, 1983.

J. C. Roberts and O. H. Griffin, Jr., “Analytical/Experimental Heat Transfer in Dry Sliding of Polymeric Composites,” Proceedings of the ASME-ASLE Joint Lubrication Conference, Washington, DC, October 5-7, 1982.

O. H. Griffin and C. M. Blackmon, “Finite Element Stress Analysis of U.S. Navy MARK 83 Base Detonating Fuze Body,” Proceedings of the Army Symposium on Solid Mechanics, Cape Cod, September, 1978.

C. R. Crowe, W. Holt, W. Mock, and O. H. Griffin, “Dynamic Fracture and Fragmentation of Cylinders,” Proceedings of the International Congress on Materials II, Boston, August 16-20, 1976.

f. Formal Reports Printed and Circulated by Agencies of the State or Federal Governments O. H. Griffin, Jr., and E.H. Glaessgen, “Finite Element Based Micro-Mechanics Modeling of Textile

Composites,” in NASA Conference Publication 3311 (Part 2), C. C. Poe, Jr. and C. E. Harris, Editors, NASA, October 1995, pp 555-586.

Lucie Parietti and O. H. Griffin, Jr., “Micromechanical Finite Element Model for Constitutive Elastoplastic Analysis of Unidirectional Fiber-Reinforced Composites,” VPI&SU Center for Composite Materials and Structures report CCMS-94-11), August 1994.

E. E. Carapella, M. W. Hyer, and O. H. Griffin, Jr., “Micromechanics of Crenulated Fibers in Carbon/Carbon Composites,” VPI&SU College of Engineering Report VPI-E-93-01 (CCMS-93-01), January 1993.

S. R. Yalamanchili, M. W. Hyer, O. H. Griffin, Jr., M. J. Shuart, C. B. Prasad and D. Cohen, “Analysis of MultiFastener Composite Joints: Numerical and Experimental Results,” VPI&SU College of Engineering Report VPI-E-92-14 (CCMS-92-15), June 1992.

J. Lee, O. H. Griffin, Jr., and Z. Gurdal, “Vibration, Buckling and Postbuckling of Laminated Composites with Delaminations,” VPI&SU College of Engineering Report VPI-E-92-13 (CCMS-92-13), June 1992.

N. L. Breivik, Z. Gurdal, and O. H. Griffin, Jr., “Compression of Thick Laminated Composite Beams with Initial Impact-Like Damage,” VPI&SU College of Engineering Report VPI-E-92-15 (CCMS-92-16) June 1992.

D. H. Mollenhauer and O. H. Griffin, Jr., “Induced Strain of Actuation of Surface Bonded and Embedded Piezoceramic Patches”, VPI-E-92-09 (CCMS-92-08) April, 1992

S. Y. Hsu and O. H. Griffin, Jr., “Efficient Endochronic Finite Element Analysis: An Example of a Cyclically Loaded Boron/Aluminum Tube,” VPI&SU College of Engineering Report VPI-E-92-8, April 1992.

S. K. Jain, S. Y. Hsu, and O. Hayden Griffin, Jr., “On the Models of Hereditary Evolutions of Plasticity,” VPI&SU Report VPI-E-91-13, June, 1991.

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D. M. Thompson and O. H. Griffin, Jr., “Development and Verification of Global/Local Analysis Techniques for Laminated Composites,” NASA Contractor Report CR-185060, (VPI-E-91-12), June 1991.

D. M. Thompson and O. H. Griffin, Jr., “Two-Dimensional to Three-Dimensional Global/Local Finite Element Analysis of Laminated Composites in Compression,” VPI&SU CCMS Report CCMS-91-14 (VPI-E-91-11), June 1991.

S. Y. Hsu and O. H. Griffin, Jr., “On Stability and Efficiency of Numerical Integration of Endochronic Constitutive Equations,” College of Engineering Report VPI-E-91-06, May 1991.

N. F. Knight, Jr., J. B. Ransom, O. H. Griffin, Jr., and D. Muheim Thompson, “Global/Local Methods Research Using the CSM Testbed,” Proceedings of the Eighth DOD/NASA/FAA Conference on Fibrous Composites in Structural Design, compiled by J. H. Starnes, Jr., H. L. Bohon, and S. B. Garzon, NASA Conference Proceeding, CP-3087, Part 1, 1990, pp 281-309.

M. A. Vidussoni and O. H. Griffin, Jr., “2-D to 3-D Global/Local Finite Element Analysis of Cross-ply Composite Laminates,” VPI&SU Report CCMS-90-09, September, 1990.

G. V. Gandhe and O. H. Griffin, Jr., “Impact Response of Interleaved Composites,” VPI&SU Report CCMS-90-01, March, 1990.

S. Y. Hsu, S. K. Jain, and O. Hayden Griffin, Jr., “Numerical Integration of the Constitutive Equations of the Endochronic Theory of Plasticity,” VPI&SU Report VPI-E-90-02, January, 1990.

S. Y. Hsu, S. K. Jain, and O. Hayden Griffin, Jr., “A Procedure for Determining Endochronic Material Functions and Verification of Endochronic Theory for Nonproportional Loading Paths,” VPI&SU Report VPI-E-89-25, June, 1989.

S. Y. Lin, O. H. Griffin, Jr., and R. M. Barker, “Feasibility of Fiber Reinforced Composite Materials Used in Highway Bridge Superstructures,” VPI&SU Report CCMS-89-05, December, 1988.

CCMS Five Year Plan Committee (O. H. Griffin, Jr., Chairman, C. E. Bakis, D. Frederick, Z. Gurdal, J. Morton, D. Post, W. W. Stinchcomb, and R. E. Swanson), “History, Current Status, and a Five-Year Plan for the VPI&SU Center for Composite Materials and Structures,” CCMS Report, April 1988.

O. H. Griffin, Jr., Z. Gurdal, and C. T. Herakovich, “Composite Materials for Rail Transit Systems,” NASA Contractor Report 178401, December, 1987.

J. L. Sevart, O. Hayden Griffin, Jr., and Z. Gurdal, “Flammability and Toxicity of Composite Materials,” VPI&SU Report VPI-E-87-33, December, 1987.

M. D. Sensmeier, O. H. Griffin, Jr., and E. R. Johnson, “Static and Dynamic Large Deflection Flexural Response of Graphite-Epoxy Beams,” VPI&SU Report CCMS-87-07 (VPI-E-87-7), May 1987. Also published as NASA Contractor Report 4118, March 1988.

O. H. Griffin, Jr., M. P. Kamat, and C. T. Herakovich, “Three Dimensional Inelastic Finite Element Analysis of Laminated Composites,” VPI&SU Report VPI-E-80-28, November, 1980. Also published as NASA Contractor Report CR-163712.

Approximately ten U.S. Naval Surface Weapons Center (now Naval Surface Warfare Center) reports, most unclassified, some classified.

I authored portions of “Virginia Institute for Materials Systems (VIMS) Interim Report” and “VIMS Final Report,” 1989 and 1990.

g.Patents/disclosures/copyrights:US Patent No. 5,612,505 “Dual Mode Warhead,” J.S. O’Brasky, A. A. Alexander, O. H. Griffin, Jr., J. S. Foster, M. C. Shamblen, March 18, 1997

5.Other: November 1983 - September 1985, Assistant Supervisor, Engineering Design Group, Johns Hopkins

University/Applied Physics Laboratory, Laurel, Maryland

Responsible for technical activities, primarily in mechanical design area, of Engineering Design Group. This group was in the same Branch as the electrical and mechanical fabrication shops, and definition and

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improvement of communication between these groups was a part of the job. Interfaced with other groups at the Laboratory to obtain projects for Engineering Design Group, which was at that time composed of 50 to 60 personnel including engineers, manual designer/drafters, CAD operators, and CAM programmers. Made both formal and informal presentations on Group capabilities and activities to both technical and management audiences. Prepared time and cost estimates for engineering jobs, supervised work, reviewed reports, and prepared performance appraisals of engineers in the Group. Supervised and participated in design of an all composite center support column for a satellite being designed and fabricated at APL. Played primary role in introducing workstation-based computer aided mechanical engineering tools to APL. Heavily involved in both hardware and software selection during a project to convert all designer/drafters at APL to CAD/CAM/CAE technology.

February 1981 - October 1983, Member, Technical Staff, Bendix Advanced Technology Center, Columbia, Maryland

Responsible for proposing, planning, and executing the composite mechanics portion of a multi-disciplinary applied research project aimed at bringing advanced composites technology into the Bendix Corporation. Areas of research included analysis of environmental and processing-induced stresses in composites, the objective being to determine means of producing laminates with extreme long-term dimensional stability. Also studied the use of micromechanics analysis to predict the thermomechanical properties of hypothetical composites. Unpublished work includes analyses conducted to determine induced stress fields and thus validate a number of non-standard tests used by Bendix personnel to evaluate experimental composite materials. Consulted with Bendix divisional personnel in the area of composite mechanics and design, including both new introduction of these materials and analysis and understanding of in-service behavior. Applications consulted on included composite airplane driveshaft, composite probe arm for precision measurement device, and composite/steel actuators for aircraft. Developed software and conducted studies of feasibility of using microprocessor based personal engineering workstations for performance of small to large scale finite element analysis.

November 1979 - February 1981, Senior Tire Development Engineer, BF Goodrich, Tire Analysis Research, Akron, Ohio

Proposing and conducting numerical research to determine proper techniques for finite element analysis of tires using both the material and geometric nonlinearity capabilities of ADINA. Research in proper application of finite element analysis to orthotropic materials. Investigated using the finite element heat transfer program ADINAT for modeling of the tire curing process. Developed pre-/post-processing and stiffness bandwidth minimization software for ADINA and ADINAT. Utilized a variety of computer tools, including DEC and IBM computers and Versatec, Tektronix, and Ramtek graphics devices.

May 1971 - October 1979, Mechanical Engineer and Aerospace Engineer, U.S. Naval Surface Weapons Center, Dahlgren, Virginia

Structures and materials specialist. Involved in design, analysis, and testing of ordnance hardware. Extensive use of finite element analysis of elastic and elastic-plastic response. Participated in research on heat transfer and loading of large caliber gun barrels and ammunition during firing and several in-service malfunction investigations. Involved in the design, prototype development, and prototype testing of the dual mode warhead for the SMAW weapon. This development was granted a Certificate of Patentability by the U.S. Navy (not patented until 1997 because of security classification). Had responsibility for building, maintaining, and user training for a library of numerical analysis (finite difference and finite element) software. Conducted numerical analysis of jointed projectile response to oblique target impact and inelastic response of composite laminates.

Awards at Virginia Tech- Academy of Teaching Excellence, 2008 Inductee- Alumni Teaching Award – 2008 (two awards per year are made across the University)

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- Diggs Teaching Scholar – 2006 (no more than 3 awards per year are made across the University)- Certificate of Teaching Excellence – Virginia Tech College of Engineering for academic years 1997-

98 and 2004-05 (no more than 4 awards per year made in the College)

Professional RegistrationRegistered Professional Engineer (Certificate 008474) in Virginia since 1976. License is current.

ConsultingHave worked with a number of attorneys in analysis of failure of consumer products and vehicle accident-related investigations.

Professional Societies- Member of American Society for Engineering Education (ASEE)- National Academic Advising Association (NACADA)

EducationFrom 2004-2010 took graduate courses in the Virginia Tech School of Education in the area of Curriculum and Instruction. Courses taken include Advanced Educational Psychology, Principles of Instructional Design, Foundations of Educational Research, Program and Platform Evaluation, Research Assessing Student Achievement and Cognitive Processes & Education.

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Faculty Information Sheet

Name: Barbara Jean Muller-Borer, Ph.D.

1.Rank: Associate Professor, Department of Engineering, East Carolina UniversityAssociate Professor, Department of Cardiovascular Sciences, East Carolina UniversityAdjunct Professor, Departments of Biology, East Carolina University

2.Degrees: Tufts University School of Engineering, Medford, MA.

Bachelor of Science in Engineering, May 1979 , Deflorez Prize in Human Engineering Senior Undergraduate Award, Tau Beta Pi Engineering Honor Society, Magna Cum Laude.

The University of North Carolina at Chapel Hill, Chapel Hill, NC. Master of Science in Biomedical Engineering, August 1986. Thesis “Control Electronics for an Implantable Hydrocephalic Shunt”.

The University of North Carolina at Chapel Hill, Chapel Hill, NC. Doctor of Philosophy in Biomedical Engineering, December 1991. Dissertation: “The Effects of Cellular Uncoupling on Action Potential Propagation in Ventricular Tissue: A Computer Modeling and Simulation Study”.

The University of North Carolina School of Medicine, Chapel Hill, NC.Postdoctoral Fellowship, Division of Cardiology, Cardiovascular Modeling. 1991-1994.

The University of North Carolina School of Medicine, Chapel Hill, NC. NIH Postdoctoral Fellowship, Division of Cardiology, Cardiovascular Physiology 1994–1996.

The University of North Carolina School of Medicine, Chapel Hill, NCPostdoctoral Fellowship, Division of Cardiology, Cardiovascular Imaging1996-1998.

3. Teaching Experience related to proposed degree (with emphasis on the past five years):Workload Assignment: 15% teaching, 75% research, 10% serviceLecturer2005 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Stem Cells

and Tissue Bioengineering”, Fall Semester, 2 lectures and 1 laboratory.2005 Division of Cardiology, Electrophysiology Noon Conference,”Cardiac Regenerative Cell

Therapy”.2006 - 2010 Department of Biology, BIOL 6880 Seminar, “Cardiovascular Translational Biology

Laboratories”. Fall Semester.2006 Division of Cardiology Grand Rounds, CME, “Cell-Based Therapy for Cardiovascular

Disease”.2006 Department of Biochemistry, Graduate Seminar, “Plasticity of a Liver Adult Stem Cell in a

Cardiac Myocyte Microenvironment”.2007 - 2010 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Stem Cells

and Tissue Bioengineering”, Fall Semester, 2 lectures and 1 laboratory.2007 Division of Cardiology Grand Rounds, CME, “Cell-Based Therapy for Cardiovascular

Disease”.2008 Department of Pathology, Grand Rounds, CME, “Stem Cell Differentiation into Cardiac

Myocytes”.2008 Department of Anatomy and Cell Biology, Graduate Seminar, “Stem Cell Differentiation

in a Cardiac Microenvironment”.2009 Department of Cardiovascular Sciences, Grand Rounds, CME, “Cardiac Regeneration

and Cell-Based therapies for Ischemic Heart Disease”. 2009 - 2010 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Laser Capture

Microdissection”, Fall Semester, 1 lecture and laboratory.

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2009 - 2010 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Cell Culture Techniques”, Fall Semester, 1 lecture and laboratory.

2009 - 2012 Department of Engineering, BIME 3000, “Introduction to Biomedical Engineering”, Fall Semester. 2 lectures

2010 Department of Cardiovascular Sciences, “Overview of Regenerative Medicine Research and Laser Capture Microdissection”. Lecture to NCState Park Fellows.

2010 Department of Physiology, “Gap Junctions: Intercellular Channels”, Lecture to graduate and undergraduate students in Tulis Laboratory.

2010 - 2011 Instructor, Brody School of Medicine Personal Professional Leadership Program.2010 - 2013 Instructor, Department of Engineering, BIME 4040, “Physiological Systems and Modeling

for Engineering”, Spring Semester, 2 lectures per week, 16 weeks.2011 Department of Cardiovascular Sciences, Grand Rounds, CME, “The Heart of the Matter:

Stem Cells”.2011 - 2013 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Laser Capture

Microdissection”, Spring Semester, 1 lecture and laboratory.2011 - 2013 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Cell Culture

Techniques”, Spring Semester, 1 lecture and laboratory.2011 - 2013 Department of Physiology, Physiological Proteo-Genomics (PHLY-7704), “Stem Cells

and Tissue Bioengineering”, Spring Semester, 1 lecture and laboratory.2012 Department of Cardiovascular Sciences, Grand Rounds, CME, “Update on Current

Cardiovascular Stem Cell Therapies”

Seminars2004 Department of Physiology, Journal Club, “Stem Cell Trans-Differentiation in a Cardiac Myocyte

Microenvironment”, October 2004.2005 Metabolic Studies Research Group, “Stem Cell Plasticity in the Cardiovascular System”, February

2005.2005 Department of Surgery, “Cardiovascular Translational Biology Laboratories”, Presentation to

visiting professor Frank Selke, MD and surgical residents, October 2005.2006 Division of Endocrinology and Metabolic Studies Group, “Confocal Fluorescence Microscopy”,

January 2006.2007 Stem Cell Interest Group, “Stem Cell Trans-Differentiation in a Cardiac Myocyte

Microenvironment”, February 2007.2007 East Carolina University Brody School of Medicine Confocal Microscopy Symposium, “Gap

Junction Coupling and Calcium Signaling in Live Cell Cultures”, November 2007.2008 Stem Cell Interest Group, “Review of Symposium on Cardiovascular Regenerative Medicine –

October 2007”, February 2008.2008 Metabolic Studies Research Group, “Mechanisms Controlling the Acquisition of a Cardiac

Phenotype by Liver Stem Cells”, March 2008.2009 Stem Cell Interest Group, “Induced Pluripotent Stem Cells”, December 2009.2012 Cardiovascular Medicine Interest Group, “Cardiology Research”, November 2012.

Course Director2007 Liaison to UNC-Chapel Hill, Fall 2007. Webcast, “Stem Cells and Maturational Lineage Biology:

Relevance in Quiescent, Regenerative and Diseased Tissues and in Clinical/Commercial Programs in Tissue Engineering and Cell Therapies Course # 625”. Collaborated with Lola Reid, PhD, UNC-Chapel Hill to coordinate the webcast of 3 weekly lectures for 16 weeks. This was the first time the course was taught over the internet using the NCREN system.

2010 East Carolina University Department of Engineering, BIME 4040, “Physiological Systems and Modeling for Engineering”, Spring Semester 2010. Developed and taught course, 2 lectures per week for 15 weeks.

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2010 Core Faculty and Research Advisor for Interventional Cardiology Program, Department of Cardiovascular Sciences.

2010 Core Faculty and Research Advisor for Cardiology Fellowship Program, Department of Cardiovascular Sciences.

2011 – BSOM, Graduate Program Co-Director, Interdisciplinary Doctoral Program in Biological Sciences.

Graduate student supervisory experience (theses/dissertations):Doctoral Student Committee

2008 – 2010 Member of doctoral student committee, Jessica Dries, PhD Candidate, Department of Physiology, “EphrinA1/EphA Receptor Tyrosine Kinase Signaling in Myocardial Infarct Repair”.

2010 – 2012 Member of doctoral student committee, Drew Rockett, PhD Candidate, Department of Biochemistry.

Doctoral Student Training2006 Preceptor, Jessica Dries, First year graduate student, Department of Physiology.

Doctoral student laboratory rotation.2008 Preceptor, Di Wu, First year graduate student, Department of Physiology.

Doctoral student laboratory rotation.

Surgical and Internal Medicine Residents2005 - 2006 Co-advisor, George Hart Tyson, MD. Third year Surgical Resident research

project, “Evaluating Microbead Injection Techniques in a Porcine Heart”. 2006 Preceptor, Christopher Karkut, MD, First year Internal Medicine Resident.

Laboratory rotation. 2006 - 2007 Co-advisor, Wes Hudson, MD. Third year Surgical Resident research project,

“Evaluating Stem Cell Delivery Techniques and Analysis in a Porcine Model”. 2006 - 2007 Co-advisor, Dorian deFreitas, MD. Third year Surgical Resident research project,

“Developing a Rodent Bypass Model”. 2008-2009 Preceptor, Jacqueline Carter, MD. Third year Surgical Resident. Laboratory

methods and training.

Masters Students 2006 – 2008 Co-Advisor, Master’s student thesis project, Graham V. Byrum III. Research

project/thesis. “Role of Thymosin Beta-4 in hMSC engraftment and differentiation in myocardial tissue “. Wake Forest Medical School, Class of 2012

2006 - 2008 Advisor, Master’s student thesis project, Yasmeen Midgette, Department of Biology. Research project/thesis, “The Effect of Mechanical Stress on the Differentiation of Mesenchymal Stem Cells into a Cardiac Phenotype in Vitro “.

2007 - 2008 Advisor, Master’s student, Catherine Gouge, Department of Biology.2008 – 2009 Advisor, Master’s student thesis project, Maria C. Collins, Department of Biology.

Research project/thesis “Expression of cardiogenic markers in bone marrow derived hMSC’s using mechanical strain and treatment with growth factors”.

2010 – 2011 Advisor, Master’s student thesis project, Katherine Crifasi, Department of Biology. Research project/thesis “What Degree of Protection does T4 hold for MSCs against Hypoxia Induced Apoptosis?”

2011 – 2012 Committee member, Divya Devadasan, ECU Department of Biology2011 – 2012 Committee member, Laura Larion, ECU Department of Biology

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Medical Students 2006 Mentor, Christopher Karkut (M4), East Carolina University Brody School of

Medicine. Individually designed selective in Cell-Based Therapy and Tissue Engineering Laboratory, “Evaluating Effects of LPS on Gap Junction Expression in Adult Stem Cells”.

2007 Research co-advisor, Brian Burrows, “Cellular loss associated with xenographic mesenchymal stem cell cardiomyopathy”. Brody School of Medicine Summer Scholars Research Program.

2009 Research advisor, Joseph B. Padgett, ”Thymosin Beta 4's Wound Healing Propensity and the Heart “. Brody School of Medicine Summer Scholars Research Program.

2010 Research co-advisor, Richard Elliott Overman, Jr,. “Effects of BAY 41-2272 on Connexin 43 Expression in Vascular Smooth Muscle Cells.” Brody School of Medicine Summer Scholars Research Program.

2012 Research advisor, Vishnupriya Khatri ” Expression of CAMTA genes in cardiac hypertrophy “. Brody School of Medicine Summer Scholars Research Program

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)a. Publications/Scholarly Activity related to proposed degree:

Muller-Borer BJ, Erdman D, Buchanan JW. "Electrical Coupling and Impulse Propagation in Anatomically Modeled Ventricular Tissue". IEEE Transactions in Biomedical Engineering (IF 1.857) 1994:41(5);445-454.

Muller-Borer BJ, Johnson TA, Gettes LS, Cascio WE. "Directional Differences in Propagation in a Modeled Ischemic Border Zone". Journal of Cardiovascular Electrophysiology (IF 3.703) 1995:6(12);1101-1112.

Hyatt CJ, Lemasters JJ, Muller-Borer BJ, Johnson TA, Cascio WE. "A Superfusion System to Study Border Zones in Confluent Cultures of Neonatal Rat Heart Cells". American Journal of Physiology (IF 4.0) 1998:274;H2001-H2008.

Muller-Borer BJ, Yang H, Marzouk SA, Lemasters JJ, Cascio WE. "Measurement of Endocardial and Subendocardial pHi and pHo in Perfused Rabbit Papillary Muscles by Confocal Fluorescent Microscopy". American Journal of Physiology (IF 4.0) 1998:275(6 pt 2);H1937-H1947.

Henriquez AP, Vogel R, Muller-Borer BJ, Henriquez CS, Weingart R, Cascio WE. "Influence of Dynamic Gap Junction Resistance on Impulse Propagation in Ventricular Myocardium: A Computer Simulation Study". Biophysical Journal (IF 4.507) 2001 Oct;81(4):2112-21.

Cascio WE, Yang H, Johnson TA, Muller-Borer BJ, Lemasters JJ. "Electrical Properties and Conduction in Reperfused Papillary Muscle". Circulation Research (IF 9.7) 2001 Oct 26;89(9):807-14.

Muller-Borer BJ, Cascio WE, Anderson PAW, Snowwaert JN, Frye JR, Desai N, Bagnell CR, Coleman WB, Grisham JW, Malouf NN. "Adult Derived Liver Stem Cells Acquire a Cardiac Myocyte Structural and Functional Phenotype in Culture". American Journal of Pathology (IF 6.039) 2004 July;165(1): 135-45.

Cascio WE, Yang H, Muller-Borer BJ, Johnson TA "Ischemia-Induced Arrhythmia: The Role Of Connexins, Gap Junctions, And Attendant Changes In Impulse Propagation”. Journal of Electrocardiology (IF 1.2) 2005 Oct;38(4 Suppl):55-9.

Muller-Borer BJ, Cascio WE, Grisham JW, Anderson PAW, Malouf NN “Acquired Cell-to-Cell Coupling and Cardiac-Like Calcium Oscillations in Adult Stem Cells in a Cardiomyocyte Microenvironment”. Proceedings of the 28th IEEE Engineering in Medicine and Biology Society, 2006;1:576-579.

Muller-Borer BJ, Cascio WE, Esch GL, Kim HS, Coleman WB, Grisham JW, Anderson PAW, Malouf NN. “Mechanisms Controlling The Acquisition Of A Cardiac Phenotype By Liver Stem Cells”. Proceedings of the National Academy of Sciences (IF 10.231) 2007 March; 104(10): 3877-3882.

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Hudson W, Collins MC, Dorian deFreitas D, Sun, YS, Muller-Borer BJ, Kypson AP. “Beating And Arrested Intramyocardial Injections Are Associated With Significant Mechanical Loss: Implications For Cardiac Cell Transplantation”, Journal of Surgical Research (IF 2.087) 2007 Oct;142(2):263-7.

Anderson PAW, Muller-Borer BJ, Esch GK, Coleman WB, Grisham JW, Malouf NN. “Calcium Signals Induce Liver Stem Cells to Acquire a Cardiac Phenotype”. Cell Cycle (IF 4.087). 2007 Jul;6(13):1565-9.

Muller-Borer BJ, Collins MC, Gunst PR, Cascio WE, Kypson AP. “Quantum Dot Labeling of Mesenchymal Stem Cells”. Journal of Nanobiotechnology (IF 5.09) 2007 Nov. 7, 5-9.

Carter, J. J., Manwaring, M.L. , Salleng, K.J. , Muller-Borer, B.J. , Collins, M.C., Stoner, M.C. “Paralysis and Cell Death from Thoracic Aortic Stenting Ameliorated by Peroxynitrite Decomposition Catalyst.” Journal of the American College of Surgeons, 2008, 207 (3 sup), 22.

Burrows, B.J., Collins, M.C., Muller-Borer, B.J.,Kypson, A.P. “Cellular Cardiomyoplasty: Results of Injected Human Mesenchymal Stem Cell Survival Rates in a Beating Rat Heart Model”. Journal of Surgical Research, 2008, 144 (2), 274-5.

Collins MC, Moore JL, Burrows BJ, Kypson AP, Muller-Borer BJ. ““Early cell loss associated with mesenchymal stem cell cardiomyoplasty””, The Open Tissue Engineering and Regenerative Medicine Journal, 2012, April; 5: 17-24

Muller-Borer BJ, Esch GL, Aldina R, Woon, Fox R, Bursac N, Hiller S, Maeda N, Shepherd N, Jin JP, Hutson M, Anderson PAW, Kirby M, Malouf NN. “Calcium Dependent CAMTA1 in Adult Stem Cell Commitment to a Myocardial Lineage”, PLoS One. 2012;7(6):e38454. Epub 2012 Jun 8.

Joshi C, Martin DN, Shaver P, Madamanchi C, Muller-Borer BJ, Tulis DA. “Control of Vascular Smooth Muscle Cell Growth by Connexin 43”, Front Physiol. 2012;3:220. Epub 2012 Jun 21.

b.Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners):Active Extramural Research Grants

Consultant , “EphrinA1-Fc Attenuates Myocardial Infarct Injury”, North Carolina Biotechnology Center, Biotechnology Research Grant (PI: Jitka I. Virag, PhD, ECU Department of Physiology). $75,000. (6/2012 – 12/2013)

Collaborating Investigator “ High speed low cost spectral domain optical coherence tomography system for intravascular imaging” NSF-SBIR (PI: Brian Cabarrus, MD, ECU Department of Cardiovascular Sciences). $80,000. (1/2013 – 12/2014 )

Collaborating Investigator “ Surgical Assessment of Bone Wax Material in a Porcine Model” Pioneer Surgical Orthobiologics. Inc.(PI: Alan Kypson, MD, ECU Department of Cardiovascular Sciences). $8000. (1/2013 – 12/2013 )

Collaborating Investigator , “NO-independent cGMP Regulation of Vascular Remodeling”. National Heart, Lung and Blood Institute R01 (PI: Dave Tulis, PhD, ECU Department of Physiology), Annual Direct Costs $252,325 (04/2010 – 04/2012).

Pending Extramural Research Grants Co-PI , “Intramyocardial EphrinA1-Fc Reduces Acute Injury and Chronic Remodeling”. National

Heart, Lung and Blood Institute R21, (PI: Jitka I. Virag, PhD, ECU Department of Physiology). $300,000. Submitted 08/2012

Funded Extramural Research Grants PI of ECU Subaward (Sole ECU Investigator ), “Mechanisms For Stem Cell Differentiation Into

Cardiac Myocytes” National Heart, Lung and Blood Institute R01 (PI: Margaret Kirby, PhD, Duke University), Annual Direct Costs $357,612 (07/2009 - 06/2011).

Funded Intramural Research Grants Principal Investigator, “Stem Cell Engraftment And Trans-Differentiation In A Cardiac Cell

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Microenvironment”. University Research Council Grant, The University of North Carolina at Chapel Hill. $4,000 (05/2003 – 04/2005).

Principal Investigator, “A Proteomic Study of Stem Cell Engraftment and Trans-differentiation to a Cardiac Phenotype”. Junior Faculty Development Award, The University of North Carolina at Chapel Hill, Committee on Faculty Research. $5,000 (01/2004 – 12/2004).

Co-PI, “Assessment of Myocardial Cellular Transplantation via Multiple Delivery Modes”, Murray and Sydell Rosenberg Foundation, A Joint Project of The Eastern Carolina Cardiovascular Institute & East Carolina University Brody School of Medicine. $125,000 (01/2005).

Principal I nvestigator, “Role of Thymosin β4 in Stem Cell Engraftment and Myocardial Tissue Regeneration”. Research Development Grant, East Carolina University Division of Research and Graduate Studies. $40,000 (07/2006 – 06/2007).

Collaborating Investigator, “Effects of Cardiopulmonary Bypass on Adult Stem Cell Transplantation”. Research Development Grant, East Carolina University Division of Research and Graduate Studies (PI: Alan P. Kypson, MD, Department of Surgery). $25,000 (07/2006 – 06/2007).

Funded Extramural Equipment and Other Grants Co-PI, “Laser Capture Microdissection: Advanced Technology for Biomedical Research”. North

Carolina Biotechnology Center Institutional Development Grant. $163,539 (01/2007). Co-Chair, “Laser Technologies and Applications Group (Laser TAG”). North Carolina

Biotechnology Center (NCBC), NCBC Science & Technology Development Program, Intellectual Exchange Group. Total funding support: $3000 per year, Awarded September 2009, Renewed September 2010.

Co- PI, “Acquisition of a Confocal Laser Scanning Microscope to Enhance Research Infrastructure”, North Carolina Biotechnology Center Institutional Development Grant, $200,000 (04/2013).

c.Invited research presentations outside ECU : Living Proof: Senior Faces of Research: Documentary video about the benefits of biomedical

research. North Carolina Association for Biomedical Research. October 2005 (interview). Gordon Research Conference in Cardiac Arrhythmia Mechanisms. “Cardiac-Like Calcium

Transients in Liver Stem Cells Co-Cultured with Cardiac Myocytes”. Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Lemasters JJ, Anderson PAW, Grisham JW, Malouf NN. Beullton, CA, February 2005.

78th Scientific Sessions of the American Heart Association. "Calcium-Driven Transcription of a Cardiac Specifying Gene Program in Liver Stem Cells ", Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Aghajanian A, Kim HS, Lemasters JJ, Kim JS, Coleman WB, Grisham JW, Anderson PA, Malouf NN. Dallas, TX, November 16, 2005.

28th IEEE EMBS Annual International Conference. Invited Speaker. Muller-Borer BJ, Cascio WE, Grisham JW, Anderson PAW, Malouf NN, “Acquired Cell-to-Cell Coupling and Cardiac-Like Calcium Oscillations in Adult Stem Cells in a Cardiomyocyte Microenvironment”. New York City, NY, August 2006 (oral presentation).

2006 Scientific Sessions of the American Heart Association. “Long-Term Labeling of Mesenchymal Stem Cells Using Quantum Dot Bioconjugates”. Muller-Borer BJ, Gunst PR, Collins MC, Cascio WE, Kypson AP, Chicago, IL, November 2006 (oral presentation).

Sigma Xi – ECU Chapter, Awards Banquet, Invited Speaker, “Mechanisms Controlling the Acquisition of a Cardiac Phenotype by Liver Stem Cells”. Muller-Borer BJ, Cascio WE, Esch GL, Kim HS, Coleman WB, Grisham JW, Anderson PAW, NN Malouf. January 2008 (oral presentation).

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Keystone Symposia on Molecular and Cellular Biology, Cardiac Disease: Development, Regeneration and Repair (D1). “Thymosin β4 Pretreatment of Human Mesenchymal Stem Cells and Rat Neonatal Cardiomyocytes”. Collins MC, Gunst PR, Byrum G, Virag JI, Muller-Borer BJ, March 17, 2009.

International Society for Stem Cell Research ” Thymosin Beta-4 Provides Enhanced Environment for Human Stem Cell Transplantation”. Collins MC, Gunst PR, Moore JL, Virag JI, Muller-Borer BJ, June 2010.

International Society for Stem Cell Research. “Simulated Cardiac Micromechanical Environment Increases Cx43 Expression and Proliferation in Human Mesenchymal Stem Cells”. Collins MC, Midgette YA, Gunst PR, Muller-Borer BJ, June 2010.

Regenerative Medicine: Harnessing Biology for Regeneration “Growth Factors Enhance Adult Stem Cell Mitochondrial Function”, Ajmera A, Collins MC; Pradhan PV; Thayne K; Anderson E; Muller-Borer BJ, Hilton Head, SC, March 2012.

International Society for Stem Cell Research. “The Role of Mitochondrial Biogenesis in Human Mesenchymal Stem Cell Differentiation and Acquisition of a Cardiac Phenotype”, Ajmera A, Collins MC, Pradhan PV, Anderson EJ, Muller-Borer BJ, Boston, MA, June 2013.

International Society for Stem Cell Research. “Dynamic Behavior of Mesenchymal Stem Cells in a Cardiac Microenvironment: A High Resolution Time-Lapse Imaging Study”, Coltrain L, Collins MC, Pradhan P, Muller-Borer BJ, Boston, MA, June 2013.

d. Book Chapters Gettes LS, Cascio WE, Johnson TA, Muller-Borer BJ, and the Experimental Cardiology Group.

Characteristics and causes of conduction changes associated with 1a and 1b arrhythmias in acute ischemia. In: Discontinuous Conduction in the Heart. Spooner PM, Joyner RW, Jalife J, editors. American Heart Association Monograph Series. Futura Publishing Company, Inc., Armonk, New York, 1997, pp 441-452.

Lemasters JJ, Qian T, Trollinger DR, Muller-Borer BJ, Elmore SP, Cascio WE. Laser Scanning Confocal Microscopy Applied to Living Cells and Tissue. In: Methods in Cellular Imaging. Periasamy A, editor. Published for the American Physiological Society by Oxford University Press, New York, NY, 2001, Chapter 5 (pp 66-87).

Collins MC, Gunst PR, Cascio WE, Kypson AP, Muller-Borer BJ. Labeling and Imaging Mesenchymal Stem Cells with Quantum Dots. Nanoparticles in Biology and Medicine. Methods Mol Biol. 2012;906:199-210, Humana Press, USA.

Collins MC, Gunst PR, Muller-Borer BJ. Functional Integration of Quantum Dot Labeled Stem cells in a Cardiac Microenvironment. Methods in Molecular Biology. Humana Press, USA pending

e. Refereed Papers Presented at Major International or National Technical Meetings Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Lemasters JJ, Anderson PAW, Grisham JW,

Malouf NN. “Cardiac-Like Calcium Transients in Liver Stem Cells Co-Cultured with Cardiac Myocytes”, Proceedings of the Gordon Research Conference in Cardiac Arrhythmia Mechanisms, February 2005.

Graff DW, Cascio WE, Muller-Borer BJ, Aghajanian A,. Sama P, Yan GX,. Devlin RB. "Zinc Produces a Transmural Voltage Gradient and Disruption of Intercellular Communication in the Heart”. Society of Toxicology, March 2005.

BJ Muller-Borer, WE Cascio, GL Esch, DW Graff , JJ Lemasters, PAW Anderson, JW Grisham, NN Malouf. “Cardiac-Like Calcium Transients in Liver Stem Cells Co-Cultured with Cardiac Myocytes”. Proceedings of the 2005 BSOM Department of Internal Medicine Research Day, May 2005.

Lindsey CW, Muller-Borer BJ, Yang H, Cascio WE. "BAYK8644 Enhances Longitudinal Conduction Velocity in Depolarized Ischemic Myocardium: Possible Role for ICa in Impulse

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Propagation". Proceedings of the 2005 BSOM Department of Internal Medicine Research Day, May 2005.

Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Aghajanian A, Kim HS, Lemasters JJ, Kim JS, Coleman WB, Grisham JW, Anderson PAW, Malouf NN, “Calcium Driven Transcription of a Cardiac Specifying Gene Program in Liver Stem Cells”. Circulation, 2005:112(17); II-266.

Muller-Borer BJ, Cascio WE, Esch GL, Graff DW, Kim HS, Lemasters JJ, Kim JS, Coleman WB, Grisham JW, Anderson PAW, Malouf NN, “Cardiac-Like Oscillations in Liver Stem Cells Induce Their Acquisition of a Cardiac Phenotype”. Proceedings of the American Society of Cell Biology, Dec. 2005.

Tyson GH, Muller-Borer BJ, Cascio WE, Chitwood WR, Kypson AP, “Cell Therapy Infusion Device”. Proceedings of the 9th Annual NewEra Cardiac Care Meeting, January 2006.

Burrows BJ, Gunst PR, Muller-Borer BJ, Cascio WE, Johnson TA, “Identification Of Border Zones In Swine Cardiac Tissue With The Use Of A Typhoon Variable Mode Imaging System”. Proceedings of the 2006 BSOM Department of Internal Medicine Research Day, May 2006.

Gunst PR, Collins M, Burrows BJ, Kypson AP, Muller-Borer BJ, “Viability Of Mesenchymal Stem Cells Labeled With Quantum Dot Nano Particles”. Proceedings of the 2006 BSOM Department of Internal Medicine Research Day, May 2006.

Muller-Borer BJ, Gunst PR, Collins MC Cascio WE, Kypson AP, “Long-Term Labeling of Mesenchymal Stem Cells Using Quantum Dot Bioconjugates”. Circulation, 2006:114(18); II-662.

Kypson A, Tyson H, Collins M, Sun Y, Nifong W, Muller-Borer B. “Significant Mechanical Loss Is Associated With Direct Intramyocardial Injection For Cellular Cardiomyoplasty”. Journal of Surgical Research, 2007:137(2);.295.

Collins MC, Hudson W, deFreitas D, Sun YS, Muller-Borer BJ, Kypson AP. “Beating And Arrested Intramyocardial Injections Are Associated With Significant Mechanical Loss: Implications For Cardiac Cell Transplantation”, Proceedings of the 2007 BSOM Department of Internal Medicine Research Day, May 2007.

Muller-Borer BJ, Cascio WE, Esch GL, Kim HS, Coleman WB, Grisham JW, Anderson PAW, Malouf NN, Mechanisms Controlling the Acquisition of a Cardiac Phenotype by Liver Stem Cells”. Proceedings of the 2007 BSOM Department of Internal Medicine Research Day, May 2007.

Burrows BJ, Collins MC, Muller-Borer BJ, Kypson AP.”Cellular Cardiomyoplasty: Results of Injected Human Mesenchymal Stem Cell Survival Rates in a Beating Rat Heart Model”. Journal of Surgical Research, 2008: 144(2);274-5

Carter JJ, Manwaring ML, Salleng KJ, Muller-Borer BJ, Collins MC, Stoner MC.” Paralysis and Cell Death from Thoracic Aortic Stenting Ameliorated by Peroxynitrite Decomposition Catalyst”. Journal of the American College of Surgeons 2008; 207(3 sup.):22.

Collins MC, Gunst PR, Virag JI, Muller-Borer BJ. “Thymosin-4 Treatment of Human Mesenchymal Stem Cells and Cardiomyocytes”. Proceedings of the 2008 BSOM Department of Internal Medicine Research Day, May 2008.

Byrum GV, Collins MC, Muller-Borer BJ, Virag JI. “ Role of Thymosin-4 in Human Mesenchymal Stem Cell Engraftment, survival and Differentiation in Murine Myocardium”. Proceedings of the 2008 BSOM Department of Internal Medicine Research Day, May 2008.

Midgette YA, Collins MC, Gunst PR, Muller-Borer BJ, “The Effects of Mechanical Strain on the Differentiation of Mesenchymal Stem Cells into a Cardiac Phenotype In Vitro”. Proceedings of the 2008 BSOM Department of Internal Medicine Research Day, May 2008.

Collins MC, Muller-Borer BJ, “Expression of Cardiogenic Markers in Bone Marrow Derived hMSC’s using Mechanical Strain and Treatment with Growth Factors”. Proceedings of the 2009 BSOM Department of Internal Medicine Research Day, April 2009.

Collins MC, Gunst PR, Byrum G, Virag JI, Muller-Borer BJ, “Thymosin β4 Pretreatment of Human Mesenchymal Stem Cells and Rat Neonatal Cardiomyocytes”, Proceedings of the Keystone Symposia

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on Molecular and Cellular Biology. Cardiac Disease: Development, Regeneration and Repair (D1), June 2009.

Moore JL ,Collins MC, Virag, JI, Muller-Borer BJ, ”Exploring Intramyocardial Stem Cell Engraftment with Laser Capture Microscopy”. Proceedings of the 2010 BSOM Department of Internal Medicine Research Day, May 2010.

Collins MC, Gunst PR, Moore JL, Virag JI, Muller-Borer BJ, ” Thymosin Beta-4 Provides Enhanced Environment for Human Stem Cell Transplantation”, Proceedings of the International Society for Stem Cell Research, 2010.

Collins MC, Midgette YA, Gunst PR, Muller-Borer BJ, ” Simulated Cardiac Micromechanical Environment Increases Cx43 Expression and Proliferation in Human Mesenchymal Stem Cells”, Proceedings of the International Society for Stem Cell Research, 2010.

Ajmera AA ,Collins MC, Pradhan PV, Anderson EJ, Muller-Borer BJ, ”The Effects of Growth Factors on the Mitochondrial Physiology of Human Mesenchymal Stem Cells”. Proceedings of the 2011 BSOM Department of Internal Medicine Research Day, April 2011.

Crifasi K, Collins MC, Muller-Borer BJ, ”Serum Deprivation and Hypoxia in Human Mesenchymal Sem Cells, and the Protective Role of Thymosin Beta-4”. Proceedings of the 2011 BSOM Department of Internal Medicine Research Day, April 2011.

Ajmera A, Collins MC; Pradhan PV; Thayne K; Anderson E; Muller-Borer BJ, “Growth Factors Enhance Adult Stem Cell Mitochondrial Function” Regenerative Medicine: Harnessing Biology for Regeneration, March 2012.

Collins MC, Sullivan ST, Muller-Borer BJ, “Integration and Differentiation of Human Mesenchymal Stem Cells on 3D Electrospun Nanofiber Scaffolds”. Proceedings of the 2012 BSOM Department of Internal Medicine Research Day, May 2012.

Brown DA, Hale SL, Del Rio C, Hamlin R, Frasier CR, Stewart LM, Patel HD, Collins MC, Muller-Borer BJ, Shaikh SR, Harris M, Fisher-Wellman KH, P. Neufer PD, Kloner RA. “Bendavia, a mitochondria-targeting peptide, reduces reperfusion injury and reactive oxygen species levels through a mechanism independent of direct oxygen radical scavenging: a multicenter study”, submitted for publication Circulation, 2012

g.Patents/disclosures/copyrights: Report of Invention -Cell Therapy Infusion Device, GH Tyson, MD, Co-Advisors Alan P.

Kypson, MD, Barbara J. Muller-Borer, Ph.D. Submitted and presented to the East Carolina University’s Office of Technology Transfer and the University Committee on Intellectual Property/Patents, January 2006.

5.Other:

a. Participation in scholarly collaborations with other universities, laboratories, & centers:PI of ECU Subaward (Sole ECU Investigator), “Mechanisms For Stem Cell Differentiation Into Cardiac Myocytes”. National Heart, Lung and Blood Institute R01 (PI: Margaret Kirby, PhD, Duke University), Annual Direct Costs $357,612 (07/2009 - 06/2011).

b. Service on related state/national/international boards or committees: Grant Peer Review

American Institute of Biological Sciences, New York State Department of Health and the Empire State Board NYSTEM Program, October 2008

Ad Hoc Peer Review er 1992-1994 IEEE Transactions Engineering in Medicine and Biology 2005 Cardiovascular Research 2005 Journal of Cardiac Electrophysiology2006 - present Engineering in Medicine and Biology Society

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2008 – 2009 Molecular Vision 2009 – 2010 Connective Tissue Research

Sigma Xi, Scientific Research Society – East Carolina University Chapter2006 – 2008 Membership Committee2009-2011 Executive Committee Secretary2009 - present Science Café, Steering Committee Member

North Carolina Tissue Engineering and Regenerative Medicine Society2012 – 2014 - Executive Committee Secretary

Employment History1979-1982 Human Factors Engineer, New Product Development, Eastman Kodak Co., Rochester, NY. 1985-1986 Masters Candidate and Research Assistant, Curriculum in Biomedical Engineering and

Mathematics, The University of North Carolina at Chapel Hill, Chapel Hill, NC. 1988-1991 Predoctoral Fellow Duke/North Carolina National Science Foundation, Engineering Research

Center for Emerging Cardiovascular Technologies, Curriculum in Biomedical Engineering and Mathematics, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

1991-1994 Postdoctoral Research Fellow, Department of Internal Medicine/Division of Cardiology, UNC School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

1994-1996 NIH Postdoctoral Research Fellow, Department of Internal Medicine/Division of Cardiology, UNC School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

1996-1998 Postdoctoral Research Assistant, Department of Internal Medicine/Division of Cardiology, UNC School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

1998-2001 Research Associate, Department of Internal Medicine/Division of Cardiology UNC School of Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.

Professional Honors and Awards2009 East Carolina University Chancellor’s Leadership Academy.2009 Bridges Academic Leadership for Women, William and Ida Friday Center for Continuing

Education, The University of North Carolina at Chapel Hill.Professional Societies1997 – present Tau Beta Pi, Engineering Honor Society1990 – present Biomedical Engineering Society1990 – present Institute of Electrical and Electronics Engineers (IEEE)1993 – present American Heart Association1997 – present Cardiac Electrophysiology Society1999 – present Sigma Xi, Scientific Research Society2005 – present International Society for Stem Cell Research2005 – present Society of Women Engineers2009 – present International Society for Heart Research

University Committees and Service2005 – present Member, Course Committee, Physiological Proteo-Genomics (PHLY-7704).2006 – present Member, Engineering Advisory Board, Department of Engineering.2006 – present Member, Biomedical Engineering Concentration Planning Committee, Department of

Engineering.2006 – present Member, Brody Women Faculty Committee.2006 – present Program Committee Co-Chair, Stem Cell Interest Group. Co-organize and arrange

monthly meetings and speakers.2006 – present Member, Brody School of Medicine Laser Capture Microdissection Advisory Board.

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2008 Member, Senior Design Capstone Project Review and Evaluation Committee, Department of Engineering.

2009 Member, Senior Design Capstone Project Review and Evaluation Committee, Department of Engineering.

2009 – 2010 Program Committee Co-Chair, Brody Women Faculty Committee. Co-organized and arranged monthly meetings and speakers. Co-organized Women in Science and Medicine Conference with the BSOM Office of Academic and Faculty Development, ECU Brody School of Medicine, March 2009.

2009 – 2010 Member, Faculty Search Committee, College of Health and Human Performance, Department of Exercise and Sport Science.

2009 – present Member, Biomedical Engineering Master’s Program Committee, Department of Engineering.

2009 – present Member, Industrial Outreach Committee, Department of Engineering.2009 – present Steering Committee Vice Chair, North Carolina Biotechnology Center Intellectual

Exchange Group for Laser Capture Microdissection (Laser TAG). 2009 – 2011 Elected Member, ECU Faculty Senate Faculty Information Technology Review

Committee, East Carolina University.2010 – 2011 Member, Brody School of Medicine Graduate Studies Committee. 2010 – 2011 Chair Brody Women Faculty Committee.2011 – present Co-Program Director for Interdisciplinary Studies Program in Biological Sciences,

Biomedical Science Graduate Program

Undergraduate Student Advising2008-2009 Instructor, Megan Watkins, Independent Study, “Analysis of Cardiac Calcium

Signaling”, Department of Engineering undergraduate student, ECU College of Technology and Computer Sciences.

2010 – present Mentor/research advisor, Arun Ajmera, recipient of ECU Early Assurance Award 2010, ECU Department of Biology. 2012 Recipient of ECU Undergraduate Research and Creative Activity Award

2011 Mentor, Daniel Deters, Summer Intern, Department of Engineering undergraduate student, ECU College of Technology and Computer Sciences.

2011 – 2012 Mentor, Shareh Hallaji, ECU Department of Biology2011 – present Mentor, Richard Steiner, ECU Department of Engineering. 2013 Recipient of ECU

Undergraduate Research and Creative Activity Award2012 – present Faculty Advisor, Senior Engineering Capstone Project, ECU Department of Engineering2012 – present Project Leader and Faculty Advisor, Senior Engineering Capstone Project, ECU

Department of Engineering2013 – present Mentor, Coriyon Arrington, ECU Department of Engineering2013 – present Mentor, Layne Barefield, ECU Department of Engineering

Other Teaching Activities2005 Preceptor, Undergraduate, 3 month laboratory rotation. Freshman undergraduate, Amherst

University, Amherst, MA.. 2006 Preceptor, Undergraduate, 3 month laboratory rotation. Park Fellow undergraduate student,

North Carolina State University, Raleigh, NC.2006 Preceptor, Undergraduate, 1 month laboratory rotation. Senior undergraduate in Biomedical

Sciences, University of South Florida, Tampa, FL.2006 Preceptor, High school student, 3 month laboratory rotation. Senior, JH Rose High School,

Greenville, NC.2006- 2007 Preceptor, Senior, JH Rose High School Medical Honors program. Greenville, NC.

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2008 Member, Review Committee, Senior Capstone Project, Department of Engineering, ECU College of Technology and Computer Sciences.

2009 Member, Review Committee, Senior Capstone Project, Department of Engineering, ECU College of Technology and Computer Sciences.

2010 Judge, Graduate Student Oral Presentation, 2010 Department of Internal Medicine Research Day.

2010 Preceptor, High school student ,1 month laboratory rotation. Junior, Chantilly HS, Chantilly, VA.

2010 – 2011 Preceptor, Senior, D.H. Conley High School Medical Honors program, Greenville, NC.Professional Development

MATLAB Fundamentals and Programming Techniques, Raleigh, NC. April 2003 Lecture and Presentation Skills, Office of Academic and Faculty Development , ECU Brody School

of Medicine. October 2004. Virtual Cell Short Course, University of Connecticut Health Center, Farmington, CT. June 2006. Basic Statistical Skills and Advanced Statistical Skills, Summer Workshop, Center for Faculty

Development, East Carolina University. June 2006. NIH Regional Seminar on Grant Preparation, Research Triangle Park, NC. April 24-26, 2007. International Society of Computerized Electrocardiography, Riverside, CA. May 1 – 5, 2008. Integrative Computational Modeling of the Cardiac Myocyte, NHLBI-JHU T15 Short course on

Myocyte Modeling, Baltimore, MD. August 18 – 22, 2008. East Carolina University Chancellor’s Leadership Academy, Office of Academic Affairs Special

Projects. Jan – May 2009. 9th Annual Coherent – Zeiss Workshop and Multiphoton Users Group Meeting, David H. Murdock

Research Institute, Kannapolis, NC. August, 27-28, 2009. Bridges Academic Leadership for Women, William and Ida Friday Center for Continuing Education,

The University of North Carolina at Chapel Hill, September – November 2009. Medical Education Grand Rounds, Blackboard, BSOM Office of Academic and Faculty

Development, ECU Brody School of Medicine. November 2009. Preparing a Personnel Action Dossier, BSOM Office of Academic and Faculty Development, ECU

Brody School of Medicine, March 2005, October 2009. Accreditation Board for Engineering and Technology (ABET) Faculty Workshop on Sustainable

Assessment Processes – January 2010.Research and Teaching Honors and Awards2005 W. James Metzger, Jr. MD, Brody School of Medicine, Department of Internal Medicine

Research Day, Junior Faculty Presentation Award.2006 Best Drawing Board Invention, “Cell Therapy Infusion Device”, Tyson GH, Co-Mentors Muller-

Borer BJ & Kypson AP. 9th Annual NewEra Cardiac Care Meeting.2007 Best Research Poster, 2007 BSOM Department of Internal Medicine Research Day. “Beating And

Arrested Intramyocardial Injections Are Associated With Significant Mechanical Loss: Implications For Cardiac Cell Transplantation”, Co-Authors Collins MC, Hudson W, deFreitas D, Co-Mentors Muller-Borer BJ & Kypson AP. Greenville, NC.

2006 Faculty Author Recognition Award, East Carolina University, Division of Health Sciences.2007 Faculty Author Recognition Award, East Carolina University, Division of Health Sciences.2008 Sigma Xi, 2008 Helms Award for Faculty Research in Biological Sciences, East Carolina

University Chapter.

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Faculty Information Sheet

Name: Jianchu (Jason) Yao, PhD

1. Rank: Associate Professor - Department of Engineering, East Carolina University

2. Degrees: Doctorate of Philosophy Electrical Engineering Dec. 2004

Kansas State University, Manhattan, KS, USA Dissertation: Design of Standards-Based Medical Components and a Plug-and-Play Home Health Monitoring System

Master of Engineering Electrical Engineering July, 1995Shaanxi University of Science and Technology, Shaanxi, China Thesis: On Papermaking Process Expert Control System

Bachelor of Science Electrical Engineering July, 1992Shaanxi University of Science and Technology, Shaanxi, China

3. Teaching Experience related to proposed degree (with emphasis on the past five years)Workload Assignment: 50% teaching, 30% research, 20% serviceAssociate Professor (Tenured) August 2010Department of Engineering, East Carolina University (ECU), Greenville, NC, 2005 –Present

Develop engineering curriculum, teach electrical engineering related courses, conduct scholarly research, and provide service to the department and the university. Specific duties and accomplishments include:

Started the Department of Engineering (General Engineering) at ECU along with other colleagues, in charge of electrical engineering curriculum and laboratory development. This includes a wide range of duties for structuring new courses from scratch, such as creating course catalog descriptions and course syllabi, identifying course-prerequisites and objectives, developing assessment instruments, planning laboratory space, and researching, purchasing, and maintaining lab equipment;

Develop, teach, and improve four courses, including both lectures and laboratories: ENGR-1014 Introduction to Engineering, ENGR-3014 Circuit Analysis, ENGR-3050 Instrumentation and Controls, and MENG 4350-Electromechanical Systems;

Teach ENGR1012-Engineering Graphics, ENGR 4501-FE Review, COAD 1000-Freshman Seminar; Advised three senior capstone projects; two projects established collaboration with the health science

campus. Started and direct the Bio-Sensors Laboratory (a research lab funded by ECU; currently has two

undergraduate students working in the lab; supported one research associate, one graduate student, and six undergraduate students); conduct technical research in telemedicine, novel application of vital sign signals, and ad-hoc research collaborating with researchers from the ECU medical and health community;

Serve on various committees: Department Assessment Committee, Engineering Core Curriculum Committee, Biomedical Engineering Committee, College International Committee, and University Teaching Grants Committee;

Serve as a reviewer for professional journals, conferences, and federal and local funding agencies Outreach K-12 students to expose them with science, technology, engineering, and mathematics.

Involvements include teaching high school summer programs, leading engineering/technology events, helping with university open houses, etc.

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4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)

a. Publications/Scholarly Activity related to proposed degree: Gregg Givens, Jianchu Yao, and Daoyuan Yao (2013), “ Innovation, Disruption and

Teleaudiology “ , Journal of Technology and Innovation, in review. Crowell, E., Givens, G., Jones, G., Brechtelsbauer, P., & Yao, J. Audiology Telepractice in a

Clinical Environment: A Communication Perspective. Journal of Otology, Rhinology and Laryngology, 120 (7), 441-447.

Howard, E., Williams R., and Yao J. (2010). “Simulations of Carnival Rides and Rube Goldberg Machines for the Visualization of Concepts of Statics and Dynamics,” Engineering Design Graphics Journal, Vol. 74, No. 2.

Yao, J., & Wan, Y. (2010). Improving Computing Efficiency of a Wavelet Method Using ECG as a Biometric Modality. International Journal of Computer and Network Security, 2(1), 15.

Yao, J., Wan, Y., & Givens, G. D. (2009). Using web services to realize remote hearing assessment. Journal of Clinical Monitoring and Computing.

Yao, J., Wan, Y., & Givens, G. (2009a). A Tele-Hearing Diagnosis System Based on Web Services (Abstract). Telemedicine and e-Health, 15(S1), 105.

Yao, J., Sullivan, S., Eckert, C., & Bartlett, E. (2009). An Orthopedic Injection Training Instrument Using Flow Impedance to Indicate Needle Tip Locations. Journal of Clinical Computing and Monitoring, 23( 6).

Yao, J., Givens, G., & Wan, Y. (2009). A Web Services-Based Distributed System with Browser-Client Architecture to Promote tele-audiology Assessment. Telemedicine and e-Health, 15(8,), 777-782.

Yao, J., & Limberis, L. (2009). Coupled-Tanks Level Control: an Effective Course Project and Its Software Design. Computer in Education Journal 19(4).

Yao, J., Limberis, L., Williams, R., & Howard, E. (2009). A Efficient PID Control Teaching Module with LabVIEW Simulation. Computer in Education Journal, 19(2), 30-41.

Yao, J., & Warren, S. (2005a). Applying the ISO/IEEE 11073 Standards to Wearable Home Health Monitoring Systems. Journal of Clinical Monitoring and Computing, 19(6), 427-436.

Yao, J., Schmitz, R., & Warren, S. (2005). A Wearable Point-of-Care System for Home Use that Incorporates Plug-and-Play and Wireless Standards. IEEE Transaction on Information Technology in Biomedicine, 9(3), 363-371.

Warren, S., Yao, J., & Lebak, J. (2005). Applying Emerging Interoperability Standards to Wearable Point-of-Care Systems (Abstract). Telemedicine and e-Health, 11(2), 193.

Yao, J., Ding, X., Zhan, Q., & Zhang, Q. (2000). On Task-based Directional Manipulability of Redundant Robot. Robots (Chinese), 22 (6).

Yao, J. (1999). Application of Single-Chipped Microcomputer on Automatic Package Machine. Machinery and Electronics (Chinese).

Yao, J., & Wang, M. (1998). Boiler Water Lever Control System in Sodium Recycling Process. Journal of Northwest Institute of Light Industry (Chinese).

Sun, Y., Yao, J., Fei, J., & Wang, M. (1998). Application of GENIE on Pulp-Making Process. Journal of Northwest Institute of Light Industry (Chinese).

b. Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners): National Science Foundation. Collaborative Research: Cyber-Physical Tools for the MOOC Age:

Personalized Hands-On Electrical Engineering Learning Experiences for Distributed Education. $150,063. 1/1/2014 – 12/31/2016. Pending. Role. PI.

National Science Foundation. “Portable Cyber-Laboratories: Virtual Instruments and Affordable Prototyping Kits to Enhance Learning and Improve Access to Electrical Engineering Education”, $88,100. Role: PI. Collaborate with Kansas State University.

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North Carolina Department of Transportation, “Fleet Management Criteria: Depreciated Life, Disposal Point & Utilization,” $95,334. Role: Co-PI. PI: Dr. Paul Kauffmann.

East Carolina University Office of Technology Transfer, Development of a Location Identification Device for Orthopedic Injections (Phase II), $1,500. Role: PI.

East Carolina University Office of Technology Transfer, Development of a Location Identification Device for Orthopedic Injections (Phase I), $6,000. Capstone project fund. Role: Faculty Advisor.

East Carolina University College of Allied Health, Development of a Web Services Based Distributed System for Tele-hearing Diagnosis, $25,000.

East Carolina University Start-up Award, Realizing Self-Help Healthcare through Pervasive Sensing and Intelligent Human-Device Interactions, $120,000. Role: PI.

ECU Teaching Grant 2013-2014: Development of a Suite of Project Modules Related to Real World in an Instrumentation and Controls Course. $10,000.

NSF-ECR program: Collaborative Research: Cyber-Physical Tools for the MOOC Age: Personalized Hands-On Electrical Engineering Learning Experiences for Distributed Education. $150,063 pending

c. Presentations/Talks “A Web Services-based Distributed System with Browser-Client Architecture to Promote

Tele-audiology Assessments”, ECU, Business of Healthcare Symposium 2010. “Conduct Scholar Research in a Developing Undergraduate Program,” East Carolina University

Engineering Advisory Board Annual Meeting, October, 27, 2009. “A Web-services Based Distributed Tele-audiology System,” East Carolina University Innovation

Expo, Brody School of Medicine, April 2, 2009. “A Web-services Based Distributed Tele-audiology System,” East Carolina University International

Scholars Symposium, April 1, 2009. “Design of PnP Home Health Monitoring Systems and Their Standards,” Chinese Academy Sciences,

Shenzhen Advanced Technology Institute, Shenzhen, China. June 4, 2008. “Development of Home Health Monitoring Systems,” Beijing University of Posts and

Telecommunications, Beijing, China. May 15, 2008. “Use a Personal Electronic Nurse to Promote Self Care,” 1st Healthcare Mini Research Symposium,

Nursing School, East Carolina University. November 9, 2006. “Plug-and-Play Home Health Monitoring Systems Using Wearable, Standards-Based Medical

Components,” Northwest Polytechnic University and Shaanxi University of Science and Technology, Xi’an, China. June 7, 2006.

“Design and Implementation of Standards-Based Point-of-care System for Home Use,” 8th Research Forum, Kansas State University, April 4, 2003, Manhattan, KS.

“Veterinary Telemonitoring for Disease Prevention in Cattle Herds,” Cattlemen’s Day, Kansas State University, March 7, 2003, Manhattan, KS.

d. Book Chapters Jianchu Yao, Yongbo Wan and Steve. Warren. Biometric Applications of One-Dimensional

Physiological Signals – Electrocardiograms. Recent Application in Biometrics. ISBN 978-953-307-488-7. Editors: Jucheng Yang and Norman Poh. InTech Publisher.

Wan, Y., & Yao, J. (2008). Human Identification with Electrocardiogram Signals: a Neural Network Approach IAENG Transactions on Engineering Technologies Volume II - Special Edition of the World Congress on Engineering and Computer Science 2008. ISBN: 978-0-7354-0663-6. American Institute of Physics, 2009.

Yao, J. (2008). Work Harder and Work Smarter to Land a Faculty Job. In Z. J. Pei (Ed.), Tips on getting an academic position. ISBN: 978-0-557-05363-6, Lulu.com, 2009.

e. Refereed Conference Proceedings :

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Yao D, Givens G., Yao J., “Using Wireless Telecommunication Technology to Promote Tele-audiology”. The 12th Annual Wireless Telecommunications Symposium. April 17-29, 2013, Phoenix, Arizona USA

Yao J, Yao D, Kim S, Givens G.”A Comprehensive Cloud-based Remote Hearing Diagnosis System”. June 20-22, 2013. Porto, Portugal.

Li, Jiting Zheng, Ruoyin Zhang, Yuru Yao, Jianchu. iHandRehab: An interactive hand exoskeleton for active and passive rehabilitation, presented at the 2011 IEEE International Conference on Rehabilitation Robotics (ICORR), Zurich, Switzerland, June 29 2011-July 1, 2011.

Yao, J., Limberis, L., & Warren, S. (2010). A Ubiquitous Laboratory Model to Enhance Learning in Electronics Courses Offered by Two Universities with Dissimilar Curricula. Presented at the 2010 Frontier in Education, Washington, DC.

Warren, S., & Yao, J. (2010). Updates to a Mobile Circuits-and-Signals Learning Kit that Incorporates a USB Data Acquisition Unit. Presented at the 2010 Frontier in Education, Washington, DC.

Warren, S., & Yao, J. (2010, June 20-23). Portable Cyber-Laboratories for Electrical Engineering Education. Paper presented at the 2010 Annual ASEE Conf., Louisville, KY, USA.

Howard, W., Williams, R., & Yao, J. (2009, October 12-18). Simulations of Carnival Rides and Rube Goldberg Machines for the Visualization of Concepts of Statics and Dynamics. Paper presented at the ASEE Engineering Design Graphics Division’s Mid Year Conference, Erie, PA.

Yao, J., Wan, Y., & Givens, G. (2009b, Sept. 3-6). Design of a Web Services Based System for Remote Hearing Diagnosis. Paper presented at the the 31st IEEE-EMBS Conf., Minneapolis, MN USA.

Yao, J., & Barttlet, E. (2009, June 14-17). Design and Prototype of an Injection Location Indicator: A Senior Capstone Project and Multi-Party Partnership. Paper presented at the 2009 Annual American Society of Engineering Education Conference, Austin, TX.

Yao, J., & Wan, Y. (2008, June 1-3, 2008). A Wavelet Method for Biometric Identification Using Wearable ECG Sensors. Paper presented at the the 5th International Workshop on Wearable and Implantable Body Sensor Networks (BSN 2008), Hong Kong, China.

Yao, J., & Limberis, L. (2008, June 22-25). A Project-Driven Approach to Teaching Controls in a General Engineering Program. Paper presented at the 2008 Annual American Society of Engineering Education Conference, Pittsburg, MA, USA.

Wan, Y., & Yao, J. (2008, October 22-24). A Neural Network to Identify Human Subjects with Electrocardiogram Signals. Paper presented at the the World Congress on Engineering and Computer Science (WCECS) 2008 of International Association of Engineers (IAENG), San Francisco, CA.

Yao, J., Sun, X., & Wan, Y. (2007). A Pilot Study on Using Derivatives of Photoplethysmographic Signals as a Biometric Identifier. Paper presented at the the 29th IEEE-EMBS Conf., Lyon, France.

Yao, J., Limberis, L., & Kauffman, P. (2007, June 21-24). An Electrical Systems Course in a General Engineering Program: Experience and Lessons. Paper presented at the Annual American Society of Engineering Education Conference, Hawaii, USA.

Wan, Y., Sun, X., & Yao, J. (2007, October 17-20). Design of a Photoplethysmographic Sensor for Biometric Identification,. Paper presented at the 2007 International Conference on Control, Automation and Systems, Seoul, Korea.

Sullivan, S., Williams, R., Howard, E., & Yao, J. (2007, June 21-24). Identifying the Content of a General Engineering Program Using Benchmarking and the Fundamentals of Engineering Examination. Paper presented at the 2007 Annual ASEE Conf, Hawaii, USA.

Yao, J., Warren, S., & Simmons, S. (2006, April, 2-4). Ease of Use Considerations for Point-of-Care Devices in Home Environments. Paper presented at the Conf. of Decentralization of Healthcare via Distributed Diagnosis and Home Healthcare (D2H2), Arlington, VA, USA.

Yao, J., & Lunsford, P. (2006, June 18-21). Laboratory from the First Day: an Efficient Method to Convey Electrical Concepts to Engineering Students. Paper presented at the 2006 Annual American Society of Engineering Education Chicago, IL.

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Yao, J., Dieck, G., Dixon, G., Howard, E., McLawhorn, S., Williams, R., et al. (2006). ‘Who is the Biggest Pirate?’ Design, Implementation, and Result of a Robotics Competition for General Engineering Freshmen. Paper presented at the 2006 Annual American Society of Engineering Education Conference, Chicago, IL.

Warren, S., Lebak, J., & Yao, J. (2006, April, 2-4). Lessons Learned from Applying Interoperability and Information Exchange Standards to a Wearable Point-of-Care System. Paper presented at the Conf. of Decentralization of Healthcare via Distributed Diagnosis and Home Healthcare (D2H2), Arlington, VA, USA.

Yao, J., & Warren, S. (2005b, September 1-4). A Short Study to Assess the Potential of Independent Component Analysis for Motion Artifact Separation in Wearable Pulse Oximeter Signals. Paper presented at the the 27th IEEE EMBS Conf, Shanghai, China.

Yao, J., & Warren, S. (2005). Stimulating Student Learning with a Novel ‘In House’ Pulse Oximeter Design. Paper presented at the 2005 Annual Conference and Exposition, American Society for Engineering Education.

Warren, S., Lebak, J., Yao, J., Creekmore, J., Milenkovic, A., & Jovanov, E. (2005, September 1-4). Interoperability and Security in Wireless Body Area Network Infrastructures. Paper presented at the the 27th IEEE EMBS Conf., Shanghai, China.

Yao, J., & Warren, S. (2004, Sept). A Novel Algorithm to Separate Motion Artifacts from Photoplethysmographic Signal Obtained with a Reflectance Pulse Oximeter. Paper presented at the the 4th Joint EMBS-BMES Conf., San Francisco, CA, USA.

Warren, S., Yao, J., Schmitz, R., & Lebak, J. (2004, Sept). Reconfigurable Point-of-Care Systems Designed with Interoperability Standards. Paper presented at the the 26th IEEE EMBS Conf, San Francisco, CA, USA.

Lebak, J., Yao, J., & Warren, S. (2004). HL7-Compliant Healthcare Information System for Home Monitoring. Paper presented at the the 26th IEEE EMBS Conf., San Francisco, CA, USA.

Yao, J., Schmitz, R., & Warren, S. (2003, Sept). A Wearable Standards-Based Point-of-Care System for Home Use. Paper presented at the the 3rd Joint EMBS-BMES Conf., Cancun, Mexico.

Warren, S., Yao, J., Schmitz, R., & Nagl, L. (2003, Sept.). Wearable Telemonitoring Systems Designed with Interoperability in Mind. Paper presented at the the 25th IEEE EMBS Conf, Cancun, Mexico.

Lebak, J., Yao, J., & Warren, S. (2003, Sept). Implementation of a Standards-Based Pulse Oximeter on a Wearable Embedded Platform. Paper presented at the the 25th IEEE EMBS Conf., Cancun, Mexico.

Yao, J., & Warren, S. (2002). Design of a Plug-and-Play Pulse Oximeter. Paper presented at the Second Joint Meeting of BMES and EMBS.

Warren, S., Yao, J., & Barnes, G. E. (2002, Oct). Wearable Sensors and Component-based design for Home Health Care. Paper presented at the the 2nd Joint EMBS-BMES Conf. , Houston, TX, USA.

f. Formal Reports

g.Patents/disclosures/copyrights : “Internet-based Multi-user Diagnostic Hearing Assessment Systems Having Client-server

Architecture with User-based Access Levels for Secure Data Exchange,” Provisional patent, 2009-2010; currently filing PCT (Patent Cooperative Treat) to protect intellectual property rights cross the world. Co-inventor: Gregg Givens

An Online Calculation Toolbox for Health Care,” Disclosed on July 29, 2011. Co-inventor: Zhibin Huang.

“Systems integrating virtual instruments and virtual reality to support ubiquitous laboratory learning,” disclosed on August 8, 2011.

5. Other:Service on related state/national/international boards or committees:

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East Carolina University Graduate Faculty East Carolina University Intellectual Property/Patent Committee: ’10 East Carolina University Teaching Grants Committee: ’07-’09. Secretary ’09 College of Technology and Computer Science International Committee: ’08-’09 Department of Engineering: Engineering Core Committee, Biomedical Engineering Concentration

Committee, Assessment Committee North Carolina Summer Ventures in Math and Science (’06-’10) Science Olympia Tournament (’09, ’10) East Carolina University Engineering/Technology Day (’06-’09) East Carolina University Open House (’05-’09) Outreach: Chinese New Year’s Traditionals presentation to 1st graders in W. H. Robinson Elementary

School, 2009

PROFESSIONAL EXPERIENCE:Research Assistant Medical Component Design Laboratory Kansas State University, Manhattan, KS 2001– 2005Designed, developed, and prototyped wearable, standards-based medical sensors and wireless body networks to construct plug-and-play health monitoring systems with an open architecture. Developed and tested a novel motion artifact reduction algorithm for wearable pulse oximeters.Accomplishments/duties include: Designed medical components in three categories (base station, data logger, and sensor unit) by

integrating Bluetooth with the Medical Information Bus; Prototyped a desktop base station with LabVIEW interfaces; a wearable, low-power data logger with

larger memory; two wearable, microcontroller sensor units (pulse oximeter and ECG); and a weight scale with temperature and humidity measuring capability;

Congregated the medical components into a plug-and-play, interoperable, scalable, dynamical health-monitoring system with an open architecture; built Bluetooth wireless body area networks and local area networks; and achieved device plug-and-play performance without human interventions;

Developed and tested a novel bio-signal process algorithm that improves signal-to-noise ratio by separating motion artifacts from desired PPG signal and calculates both venous and arterial oxygen saturation, surpassing its traditional alternatives that can only compute the arterial oxygen saturation.

Research Engineer Robotics Research InstituteBeijing, China 1998–2000Researched redundant robot kinetic control and tasks-based directional manipulability to maximize path planning with given tasks; built motion control units for modular robots which can work either as a stand-alone controller or under a host controller with commands received over a RS-232 serial port.

Controls Engineer and Group Leader Institute of Microcomputer Applications, Shaanxi, China 1995–1998 Design, developed, and installed SCADA (supervisory control and data acquisition) systems for industrial processes, primarily focusing on manufacturing processes in pulp & paper industry. Managed two projects with 4 members – assigned work to members, planned timelines, and examined daily progress.Responsibilities include:

Analyzed target processes and documented system specifications; Evaluated, selected, and integrated components (sensors, controllers, and actuators); Designed control algorithms and human-machine interfaces; Tuned control parameters (e.g., PID); Performed field installation, debugging, and testing; Oversaw two contract projects valued at $150,000.

Representative projects:

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Designed and developed SCADA systems for the following pulp & paper processes: Sodium recycling, Linqing Pulp & Paper Inc. Shangdong, Jan.1997–July, 1998Pulp plant, Zhongwei Pulp & Paper Inc. Ningxia, Sep.1996–Apr. 1997 Paper basis weight & moisture, Dongying Papermaking Co., Shangdong, Jan. 1995–Sep. 1996Pressurized Headbox, Shouguang Pulp & Paper Inc., Shangdong, July 1995–Feb.1996

Implemented sequence-control for automatic package machines.

HONORS AND AWARDS The Oppenheimer Award: 64th ASEE Engineering Design Graphics Division’s Mid Year Conference,

2009 (coauthor: William Howard, Rick Williams) Treasured Pirate Award 2009 for Display of Creativity and Initiative, East Carolina University International Travel Award to present papers at Hong Kong and Shenzhen, China, ECU International

Affairs Office, 2008. Best Paper Nominee, Experimentation and Laboratory-Oriented Studies, ASEE 2008, (coauthor:

Loren Limberis) Elevated to IEEE Senior Member in 2007 New Faculty Research Award, 2006. East Carolina University Graduate Travel Award, Kansas NSF EPSCoR, 2004 Graduate Travel Award, Kansas State University Graduate Student Council, 2003

REVIEWER: IEEE Transactions on Instrumentation and Measurement Sensors China National Science Foundation proposal review, 2011 National Science Foundation proposal review panelist, twice in 2006 Technology Interface Journal International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC ’07-’09) American Society of Engineering Education Annual Conference (ASEE ’06-’09) International IEEE Conference on Industrial Informatics (INDIN 2006) International IEEE Conference on Control, Automation and Systems (ICCAS 2007)

PROFESSIONAL DEVELOPMENT: “Conducting Rigorous Research in Engineering Research” Workshop, Golden, CO (4 days, August,

2010) ABET Accreditation Assessment Training Workshop, Baltimore, MD (one day, February, 2007) MIT Leadership Skill Workshop, Boston, MT (two days, July, 2007) VaNTH ERC “How People Learn Engineering” Workshop, Nashville, Tennessee (two days, April,

2006)

MEMBERSHIPS2001 – Present Institute of Electrical and Electronics Engineers (IEEE) (S’01-M’05-S’07)2009 – Present American Telemedicine Association 2002 – Present IEEE Engineering in Medicine and Biology Society2005 – Present American Society of Engineering Education2003 IEEE Instrumentation and Measurement Society

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Faculty Information Sheet

Name: Loren Limberis, PhD1. Rank: Associate Professor of Engineering - East Carolina University

2. Degrees: University of Utah, Department of Bioengineering, 2006 Ph.D. in BioengineeringDissertation title: Toward Kinesin-Powered Chemomechanical Devices

University of Utah, Department of Electrical and Computer Engineering, 1992 B.S. Electrical Engineering

3.Teaching Experience: Workload Assignment: 45% teaching, 30% research, 25% service

Assistant Professor of Engineering Fall 2006—present East Carolina University

Assistant Professor of Electrical and Biomedical Engineering Fall 2002 – Spring 2006The College of New Jersey

Teaching Assistant, Department of Bioengineering Fall 1998Biopolymer CharacterizationUniversity of Utah

Teaching Assistant, Department of Biology Fall 1993Human PhysiologyUniversity of Utah

Courses:BIOE 3000 Bioprocess Engineering Systems (with laboratory)BIOE 3016 Engineering Applications in MicrobiologyBIOE 4010 Bioprocess Separation Engineering (Developed and delivered 4-week laboratory)BIOE 4020 Bioprocess Plant Design, Simulation, and AnalysisBIOL 7345 Cell Motility (Guest lecturer)COAD 1000 Engineering Freshmen ExperienceENGR 1014 Introduction to Engineering (with laboratory)ENGR 3014 Circuit Analysis (with laboratory)ENGR 3050 Instrumentation and Control Systems (with laboratory)ENGR 3902 Undergraduate Research in EngineeringENGR 3903 Undergraduate Research in Engineering ENGR 4010 and 4020 Senior Capstone (Faculty advisor)ITEC 2010 Introduction to Industry and Technology (Guest lecturer)

4.Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)a. Publications/Scholarly Activity related to proposed degree:

Williams, R., Klein-Gardner, S., Limberis, L., and Sullivan S. (2012) The Implementation of a Challenge-Based Curriculum into a Bioprocess Engineering Program. International Journal of Engineering Education. 28(5):1150-1160

Limberis, L. and Yao, J. (2012) From Parallel Plates to LabVIEW Program Design: An Effective Capacitive-Based Liquid Level Instrumentation Course Project. Computers in Education Journal. 22(1):99-112.

Limberis, L. and Beierlein, J. (Submitted June 2011;revising for resubmission) How to Approve Biosimilars: An Analysis of the FDA’s Public Hearings on the Implementation of the Biologics Price Competition and Innovation Act of 2009. National Center for Case Study Teaching in Science.

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Yao, J. and Limberis, L. (2009) Coupled-Tanks Level Control: An Effective Course Project and Its Software Design. Computers in Education Journal. 19(4):53-62.

Yao, J, Limberis, L, Williams, R, Howard, E. (2009) An Efficient PID Control Teaching Module with LabVIEW Simulation. Computers in Education Journal. 19(2):30-41.

Limberis, L., Magda, J.J., and Stewart, R.J. (2001) Polarized alignment and surface immobilization of microtubules for kinesin-powered nanodevices. Nano Letters 1:277-280.

Limberis, L. and Stewart, R.J. (2000) Toward kinesin-powered microdevices. Nanotechnology 11:47-51.

Ho, C-H., Limberis, L., Caldwell, K.D., and Stewart, R.J. (1998) A metal-chelating pluronic for immobilization of histidine-tagged proteins at interfaces: immobilization of firefly luciferase on polystyrene beads. Langmuir 14:3889-3894.

b. Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners): Limberis, L. (PI) & Hu, X-H. “Engineering photoreceptor-controlled aggregation and disaggregation

of nanoparticle suspensions as a platform for biotechnology devices,” North Carolina Biotechnology Center Biotechnology Research Grant (BRG), ($82,500).

Williams, R. (PI), Aswell, J., Limberis, L., Amico, L., Picard, G., Umphlett, R., Yarley, D., “Integration of Hands‐on Short Courses into a Bioprocess Engineering Curriculum,” North Carolina Biotechnology Center Education Enhancement Grant (EEG), ($59,533).

Limberis, L. (PI) & Millard, S., “Project Photo-Link: Photoreversible Control of Nanoparticle Aggregation and Disaggregation as a Platform for Biotechnology Devices,” Office of Technology Transfer, East Carolina University, ($5,000).

Limberis, L. (PI), Stellwag, E., Bier, M., & Hu, X., "Development of a Biohybrid DNA Separation Device Featuring Fast and Linear Separation with Single Base Pair Resolution," Research Development Award (RDA) Program at ECU, ECU Research Development Award (RDA) Program, ( $19,820).

Williams, R. (PI), Klein, S., Limberis, L., & Sullivan, S., "Design and Development of Educational Modules for Bioprocess Engineering," GOV-National Science Foundation (NSF), ( $136,480).

Small Grants VaNTH – “How People Learn Engineering” Workshop Scholarship 2007 The College of New Jersey – Support of Scholarly Activity 2006

3 credit course release The College of New Jersey – Support of Scholarly Activity 2005

3 credit course release Biobased Engineering Fellowship, The Whitaker Foundation 1996 National Institutes of Health Research Training Grant 1995

c. Invited research presentations outside ECU: Limberis, L . and Yao, J. (2011) Temperature Alarm Laboratory Design Project for a Circuit Analysis

Course in a General Engineering Curriculum; American Society for Engineering Education (ASEE) Annual Conference Proceedings—ASEE Annual National Conference, June 2011, Vancouver, BC, Canada.

Klein, S., Williams, R., Limberis, L., and Sullivan, S., (2009) Bioprocess Engineering Curriculum Development and Assessment—ASEE Annual National Conference, June 2009, Austin, TX.

Nanoengineering with Motor Proteins, Guest Lecturer BIOL 7345 Cell Motility (Spring 2010) Introduction to Biotechnology, Guest Lecturer ITEC 2010 Introduction to Industry and Technology

(Fall 2007; Spring 2008) Nanosystem Engineering with Kinesin Motor Proteins. Invited presentation at Science at the

Starlight; North Carolina Biotechnology Center and Sigma Xi The Scientific Research Society, Greenville, North Carolina, December 2007.

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Nanoengineering with Motor Proteins, Professional Engineers of North Carolina, Greenville, NC, February 2007

Nanoengineering with Motor Proteins, The College of New Jersey, Ewing, NJ, March 2005 Introduction to Biotechnology, The College of New Jersey, Ewing, NJ, March 2005 Ultrasonic Bioinstrumentation, The College of New Jersey, Ewing, NJ, March 2005 Review of Mathematics (Fundamentals of Engineering Review Course) The College of New Jersey,

Ewing, NJ, February 2005 Review of Chemistry (Fundamentals of Engineering Review Course) The College of New Jersey,

Ewing, NJ, February 2005 What is Bioengineering?, The College of New Jersey, Ewing, NJ, October 2004 Toward Kinesin-Powered Chemomechanical Devices, The College of New Jersey, Ewing, NJ,

December 2003 The Emerging Field of Biomedical Engineering: Opportunities for all Engineering Disciplines The

College of New Jersey, Ewing, NJ, October 2003 Toward Kinesin-Powered Chemomechanical Devices, The College of New Jersey, Ewing, NJ,

October 2002 Kinesin-Based Active Microdevices, Department of Bioengineering, University of Utah, Salt Lake

City, UT, October 2000 Overview of Microtubule Motor Proteins; In Vitro Kinesin Motility, Department of Bioengineering,

University of Utah, Salt Lake City, UT, November 1999.

d. Invited Book Chapters: Stewart, R.J. and Limberis, L., (2007) Engineering a Molecular Railroad, In: NanoBioTechnology:

BioInspired device materials of the future; Editors: Oded Shoseyov and Ilan Levy, Humana Press, NJ.

e. Peer-Reviewed Conference Proceedings Williams, R., Limberis, L., Umphlett, R., and Yarley, D. (2012) Professional development-styled

short courses for a highly effective bioprocess engineering laboratory experience; American Society for Engineering Education (ASEE) Annual Conference Proceedings—ASEE Annual National Conference, June 2012, San Antonio, TX.

Limberis, L. and Yao, J. (2011) Temperature Alarm Laboratory Design Project for a Circuit Analysis Course in a General Engineering Curriculum; American Society for Engineering Education (ASEE) Annual Conference Proceedings—ASEE Annual National Conference, June 2011, Vancouver, BC, Canada. (Best Paper Award—Division of Experimentation and Laboratory Oriented Studies)

Yao, J., Limberis, L., and Warren, S. (2011) Using Portable Electronics Experiment Kits for Electronics Courses in a General Engineering Program; American Society for Engineering Education (ASEE) Annual Conference Proceedings—ASEE Annual National Conference, June 2011, Vancouver, BC, Canada.

Yao, J., Limberis, L., and Warren, S., (2010) Work in Progress – A ubiquitous laboratory model to enhance learning in electronics courses offered by two universities with dissimilar curricula. Frontiers in Education Annual Conference, Washington, DC.

Williams, R., Klein, S., Limberis, L., and Sullivan, S., (2009) Design and Development of Educational Modules for Bioprocess Engineering. American Society for Engineering Education (ASEE) Annual Conference Proceedings—ASEE Annual National Conference, June 2009, Austin, TX.

Klein, S., Williams, R., Limberis, L., and Sullivan, S., (2009) Bioprocess Engineering Curriculum Development and Assessment. American Society for Engineering Education (ASEE) Annual Conference Proceedings—ASEE Annual National Conference, June 2009, Austin, TX.

Yao, J, Limberis, L. (2008) A Project-Driven Approach to Teaching Controls in a General Engineering Program. American Society for Engineering Education (ASEE) Annual Conference Proceedings—ASEE Annual National Conference, June 2008, Pittsburgh, PA.

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Yao, J., Limberis L., and Kauffmann, P. (2007) An Electrical Systems Course in a General Engineering Program; American Society for Engineering Education (ASEE) Annual Conference Proceeding.

Sepahpour, B. Clark, E. and Limberis, L. (2004) Modular Lumped Mass Experiment, Experimentation & Laboratory Oriented Studies; American Society for Engineering Education (ASEE) Annual Conference Proceedings.

Limberis, L. and Stewart, R.J. (1998) Biological transport in a microfabricated device: active immunochromatography with motorized antibodies; in Microfluidic Devices and Systems, A. Bruno Frazier, Chong Hyuk Ahn, Editors, Proceedings of SPIE Vol. 3515, 66-75.

Limberis, L., Ho, C-H., and Stewart, R.J. Kinesin-powered microchemomechanical systems(MCMS). Seventh Foresight Conference on Molecular Nanotechnology, October 1999, SantaClara, CA.

f. Formal Reports

g. Patents/disclosures/copyrights: Metal-Chelating Surfactant. U.S. Patent 6,087,452—July 11, 2000. Inventors Russell Stewart, Karin

D. Caldwell, Chih-hu Ho, and Loren Limberis5.Other:

Professional Employment: Research Assistant, Biomolecular Engineering Laboratory 1995 – 2001

University of Utah, Department of Bioengineering Research Associate 2000 – 2001

Allvivo of Birmingham, Alabama, University of Utah Research Analyst 1994 – 1995

Southwest Research InstituteHill Air Force Base, Clearfield, Utah

Service on related state/national/international boards or committees:Reviewer IEEE Transactions on Advanced Packaging Special section on Packaging for Micro/Nano-Scale Systems ASEE Annual Conference Proceedings NSF Career Awards ECU Undergraduate Research and Creative Activities grant reviewer

Faculty Advisor 2009 – present ISPE ECU Student Chapter

Student Activities Coordinator 2002 – 2006 IEEE Princeton/Central New Jersey Section (Region 1) Includes Princeton University, The College of New Jersey, Rutgers University, Middlesex County College, and DeVry University

East Carolina University and Engineering Department Committees: Departmental Bioprocess Engineering Committee (Chairman) (2006-present) Departmental Assessment Committee (2006-present) Departmental Biomedical Engineering Curriculum Committee (2006-2009) Departmental Capstone Committee (2008-present) University Undergraduate Research and Creative Activities Committee (2006-present)

Affiliations International Society for Pharmaceutical Engineering (ISPE) American Society Engineering Education (ASEE)

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Graduate Research Committee Membership Tess Byers (2008-2009) Master’s Thesis Committee Member (Paul Gemperline Chair) – Research

involves slurry sampling, measurement, and chemometric methods of evaluation.

Undergraduate Research Projects and Senior Theses Supervised: DSM Water Conservation (2010-2011) Faculty Advisor Design and Optimization of Firefly Luciferase Production, Purification, and Characterization at the Benchtop Bioreactor Scale (2008-2009) Faculty Advisor IEEE Micro-mouse (2004-2006) Co-advisor The 2005-2006 team won first place in the 2006 IEEE Region 1 Micro-mouse competition in Maine

and was awarded $700 The 2004-2005 team won first place in the 2005 IEEE Region 1 Micro-mouse competition in Buffalo,

NY and was awarded $1000. Home Theater Calibration System (2003-04) Principal Advisor Prosthetic Hand (2002-2004) Co-advisor Use of emerging technologies for a distributed HVAC system in Armstrong Hall (2002-03) Co- Advisor

Professional Workshops Attended that are Related to Teaching: VaNTH workshop on “How People Learn Engineering”, February 2007, Vanderbilt University Council on Undergraduate Research workshop titled “Institutionalizing Undergraduate Research”, October

2004, The College of New Jersey Week-long NSF sponsored workshop titled “How to Engineer Engineering Education”, July 2004,

Bucknell University

AwardsCentennial Award for Excellence (Spirit) – East Carolina University 2010

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Faculty Information Sheet

Name: Stephanie M. George, PhD1. Rank: Assistant Professor of Engineering - East Carolina University

2. Degrees: Ph.D. Biomedical Engineering, August 2008 Georgia Institute of Technology, Atlanta, Georgia Emory University, Atlanta, GeorgiaClassification of Portal Hypertension and Cirrhosis using Magnetic Resonance Imaging- Using MRI to classify and quantify the hemodynamics of the portal venous system as relating to portal hypertension and cirrhosis.

Advisor: Don P. Giddens, PhD, Dean of Engineering

B.S. Engineering Science and Mechanics, May 2002 Virginia Polytechnic Institute and State University, Blacksburg, Virginia

3. Teaching Experience related to proposed degree (with emphasis on the past five years):Workload Assignment: 60% teaching. 30% research, 10% serviceAssistant Professor of Engineering, August 2010 to Present

College of Technology and Computer ScienceEast Carolina University, Greenville, NC

Teaching undergraduate courses, ENGR 1012, ENGR 2000, ENGR 3024, BIME 2080 (3000), BIME 4030, Capstone advisor Designed and re-designed biomedical engineering concentration courses (BIME 2080/3000 and BIME 4030) including labs

Problem Based Learning Across the Curriculum Fellowship, Fall 2007-Spring 2009Center for Science Education, Emory University

Designed, implemented and assessed problem based learning cases at a City of Atlanta High School

Gandy/Diaz Teaching Fellowship, Fall 2007, Spring 2008, Spring 2010, Summer 2010Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech

Designed, implemented and assessed cases in an undergraduate biomedical engineering problem based learning class, BMED 1300

Developed and gave lecture on mathematical modeling Facilitated small groups of students as they solved cases

Engineering Science I, Graduate, Spring 2005Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech and Emory University

Held review and homework help sessions Graded papers

Problem Based Learning II, Undergraduate BMED 2300, Fall 2004Wallace H. Coulter Department of Biomedical Engineering, Georgia Tech

Facilitated small group of students and assessed research, teamwork, and communication skills

T.A.T.T.O Training, Emory University, Fall 2003 Teacher Assistant training

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)

Publications/Scholarly Activity related to proposed degree: S.M. George, D.R. Martin and D.P. Giddens. Portal Vein Hemodynamics in Normal Subjects and

Patients with Chronic Liver Disease. In Submission to Journal of Biomechanical Engineering.

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S.M. George, J.N. Oshinski, F.C. Tong and D.P. Giddens. Quantitative Comparison of Velocity Values from MRI and Computational Fluid Dynamics. Annals of Biomedical Engineering. In Preparation.

S.M. George, B. Fasse and K.S. Lee. Acquiring Experimental Design Skills Through Problem-Based Learning. In Preparation.

S.M. George, D.R. Martin and D.P. Giddens. Portal Vein Contribution to the Right and Left Lobes of the Liver Using MRI and CFD. 6th World Congress of Biomechanics (WCB 2010). August 1-6, 2010 Singapore, IFMBE Proceedings, 2010, Volume 31, Part 2, 473-476.

Y.Yang, S. George, D. Martin, A. Tannenbaum, and D. Giddens. 3D Modeling ofPatient-Specific Geometries of Portal Veins Using MR Images. In Proceedings ofthe 28th IEEE EMBS Annual International Conference, pages 5290-5293, 2006.

Invited research presentations outside ECU: S.M. George, P. Ghasemi, S. Mehra, S. Sharma, and J. Cahill. Investigation of Pulmonary Artery

Hypertension in Patients with Sickle Cell Disease. 2012 Biomedical Engineering Society Annual Meeting. Atlanta, Georgia. October 2012 (see II.E)

Cao and M. Mehdi. A Simple, Cost Effective Shoulder Dislocation Task Trainer. 2012 Biomedical Engineering Society Annual Meeting. Atlanta, Georgia. October 2012* student presenters

S.M. George, A.Cao, D.P. Giddens, J.N. Oshinski, F.C. Tong. Quantitative Hemodynamic Comparison of Velocity Values from Computational Fluid Dynamics and Phase-Contrast MRI in an In-Vitro Aneurysm Model. Proceedings of the ASME 2012 Bioengineering Conference. Farjado, Puerto Rico, June 2012.

Cao, J.N. Oshinski, F.C. Tong, and S.M. George. Quantitative Comparison of Computational Fluid Dynamics and MRI Velocity Values in an in-vitro Aneurysm Model. National Conference on Undergraduate Research. Ogden, UT. March 2012.*student presenter

Cao, J.N. Oshinski, F.C. Tong, and S.M. George. Quantitative Comparison of Computational Fluid Dynamics and MRI Velocity Values in an in-vitro Aneurysm Model. State of North Carolina Undergraduate Research and Creativity Symposium. Greenville, NC. November 2011.*student presenter

E. Mitchell and S.M. George. A Sickle Cell Disease Learning Module for Middle School Classrooms. State of North Carolina Undergraduate Research and Creativity Symposium. Greenville, NC. November 2011.*student presenter

D. Rogers, A. Bott, J. Browder, A. Malicdem, S.M. George. Design of a Mechanical Labor and Delivery Bed for Low Resource Settings. State of North Carolina Undergraduate Research and Creativity Symposium. Greenville, NC. November 2011.*student presenters

K. Abshire, P. Watson, J.N. Oshinski, F.C. Tong, and D.P. Giddens, S.M. George. Quantitative Comparison of Computational Fluid Dynamics and MRI Velocity Values in an in-vitro Aneurysm Model. Summer Scholars Research Day. Greenville, NC. August 2011.*student presenter

S.M. George, B. Fasse and K.S. Lee. Acquiring Experimental Design Skills Through Problem-Based Learning. 2010 Biomedical Engineering Society Annual Meeting. Austin, Texas. October 2010.

S.M. George, D.R. Martin and D.P. Giddens. Portal Vein Contribution to the Right and Left Lobes of the Liver Using MRI and CFD. 6th World Congress of Biomechanics (WCB 2010). Singapore, August 2010.

S.M. George, P. Watson, J.O. Oshinski, C.W. Kerber, D. Karolyi, F.C. Tong, D.P. Giddens. Computation Analyses of an In-Vitro Aneurysm Model Based on Three-Dimensional Angiography with Comparison to Phase Contrast Magnetic Reonance Imaging and Dye Injection Studies. Proceedings of the ASME 2010 Summer Bioengineering Conference, Naples Florida, June 2010

S. M. George, D. R. Martin, and D. P. Giddens. Computational Analysis of Flow in the Portal Vein of Normal Subjects and Patients Using MRI and CFD. Electronic Poster Presentation at the

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International Society for Magnetic Resonance in Medicine 2010 Annual Meeting. Stockholm, Sweden. May 2010.

S.M. George, D.R. Martin, D.P. Giddens. Contribution of Superior Mesenteric Vein Flow to the Right and Left Lobes of the Liver Using CFD. Proceedings of the ASME 2008 Summer Bioengineering Conference, Lake Tahoe, CA. June 2009.

S. M. George, D. R. Martin, and D. P. Giddens. Hemodynamic Investigation of Flow in the Normal Portal Vein. Student Poster Competition. Proceedings of the ASME 2008 Summer Bioengineering Conference. Marco Island, Florida. June 2008.

S. M. George, P. Sharma, D. R. Martin, and D. P. Giddens. Geometry and Flow in the Portal Vein of Normal Subjects and Patients using Magnetic Resonance Imaging. Electronic Poster Presentation at the International Society for Magnetic Resonance in Medicine 2008 Annual Meeting. Toronto, Ontario. May 2008.

S.M. George, P. Sharma, Y. Yang, Y. Gao, D.R. Martin and D.P. Giddens. Investigation Of Geometry And Flow In The Portal Vein Using Magnetic Resonance Imaging Poster Presentation at Biomedical Engineering Society 2007 Annual Meeting. Hollywood, CA. Sept. 2007.

S.M. George, D.R. Martin and D.P. Giddens. A Computational Model of Hemodynamics in the Portal Vein. Poster Presentation at Biomedical Engineering Society 2007 Annual Meeting. Hollywood, CA. Sept. 2007.

S.M. George. Medieval Women Mystics and the Question of Anorexia. Conference on Gender Studies, Radford University, Radford, Virginia, March 2001

5. Other Research Experience:

Comparison and Statistical Validation of Cerebral Flow Results Obtained Using Phase Contrast MRA and Computational Flow Dynamics in an In Vitro Cerebral Aneurysm Model. August 2009 to Present Frank Tong, M.D., Emory University, Atlanta, GA

Developed computational models of two cerebral aneurysm models Validated and compared the in vitro measurements with computational results

Patient Outcome Assessment Comparative Evaluation: Rabia Balkhi Hospital, Afghanistan, January 2009 to October 2009 (unpaid)Denise Giles, MPH, WHO Collaborating Center in Reproductive Health, Centers for Disease Control and Prevention, Atlanta, Georgia

Comparison of YR2003, YR2005, and YR2008 Patient Outcome Assessment data using epidemiologic and industrial systems engineering methods.

Improvement of maternal and newborn services in a low resource setting. Calculation of risk profiles and modeling of risk through health services areas.

Post-Doctoral Fellowship, August 2008 to August 2010Diego Martin, M.D., PhD and Don Giddens, PhD, Georgia Tech and Emory University, Atlanta, Georgia

Investigated clinical significance of hemodynamic parameters to diagnosis, progression and monitoring of chronic liver disease.

Used CFD to determine source of the right liver lobe’s blood supply

Effect of Problem Based Learning on Undergraduate Students, July 2008 to Present Barbara Fasse, PhD, Dept. of Biomedical Engineering, Georgia Tech, Atlanta, Georgia

Created scoring system for pre- and post-Problem Based Learning assessments Quantitatively measured experimental design knowledge gained from PBL

Doctoral Student, August 2002 to August 2008Don Giddens, PhD, Georgia Tech and Emory University, Atlanta, Georgia

Optimized data acquisition for portal vein geometry and flow measurements using MRI and phase contrast-MR

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Analyzed normal subject and patient flow data to determine potential parameters that may change due to disease

Created four computational model of the blood flow within the portal vein

Investigating the Use of Resin, Summer 2003 Robert Taylor, M.D., PhD Emory University, Atlanta, Georgia

Researched different types of resin and tested them as a means of fixing tissues. Constructed polymerization chamber, cut histological sections using microtome and

conducted tissue staining.

Imaging Aortic Wall Compliance using MRI and High Speed Camera Imaging, Spring 2003 John Oshinski, PhD, Emory University, Atlanta, Georgia

Measured the area changes of a phantom model using MRI and high speed camera imaging and compared the results.

Co-op Student, Jan 2000 to May 2000, Aug 2000 to Jan 2001, May 2001 to Aug 2001 DuPont Advanced Fiber Systems- Kevlar, Richmond, Virginia

Hypothesized and tested design differences in parts to determine potential causes of process instability

Developed and implemented Uptime model for use in monitoring, auditing, and upgrading Kevlar performance

Learned and applied Six Sigma tools and methodology in polymer isolation, pump reliability, and fiber materials handling

Pending Extramural Research GrantsPI, “MR and Computational Analysis of the Pulmonary Artery and Right Ventricle in Pulmonary Hypertension”, American Heart Association Beginning Grant-in-Aid Mid-Atlantic Affiliate, $153,115, Submitted 1/22/13.

PI, “Hemodynamic Investigation of Pulmonary Hypertension using MRI and CFD”, NIH Heart, Lung, and Blood Institute, $440,396, Submitted 2/25/13.

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Faculty Information Sheet

Name: Sunghan Kim, PhD1. Rank: Assistant Professor of Engineering - East Carolina University

2. Degrees: 2005 – 2009 Ph.D. Electrical and Computer Engineering, Portland State University, Oregon, U.S.A.2003 – 2005 M.S. Electrical and Computer Engineering, Portland State University, Oregon, U.S.A.2001– 2003 B.S. Electrical and Computer Engineering, Portland State University, Oregon, U.S.A.1995 - 1997 Transfer Electrical Engineering, Korea University, Seoul, Korea

3. Teaching Experience related to proposed degree (with emphasis on the past five years)Workload Assignment: 65% teaching. 20% research, 15%

Teaching ExperienceCourses:East Carolina UniversityBIME 4200 Biomedical InstrumentationENGR 1012 Engineering GraphicEENG 3020 Signals and SystemsENGR 1016 Introduction to Engineering Design

Portland State UniversityECE 223 Signal & System II, instructor ECE 223 Signal & System II, instructor ECE 223 Signal & System II, teaching assistantECE 203 Signal & System II, lab instructorECE 222 Signal & System I, guest lecturerECE 302 Electric Circuit II, lab instructorECE 222 Signal & System I, teaching assistant

4.Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years):a. Publications/Scholarly Activity related to proposed degree :

S. Kim, R. Hamilton, S. Pineles, M. Bergsneider, and X. Hu, “Noninvasive Intracranial Hypertension Detection Utilizing Semi-Supervised Learning,” IEEE Transactions on Biomedical Engineering, Accepted.

X. Hu, M. Sapo, V. Nenov, T. Barry, S. Kim, D. Do, N. Boyle, and N. Martin, “Predictive Combinations of Monitor Alarms Preceding In-Hospital Code Blue Events,” Journal of Biomedical Informatics, in press.

S. Kim, M. Aboy, and J. McNames, “Pulse Pressure Variation Tracking using Sequential Monte Carlo Methods,” Biomedical Signal Processing and Control, Accepted in January 2012.

F. Scalzo, R. Hamilton, S. Asgari, S. Kim, and X. Hu, “Intracranial Hypertension Prediction using Extremely Randomized Decision Trees,” Medical Engineering & Physics, Accepted in November 2011.

F. Scalzo, S. Asgari, S. Kim, M. Bergsneider, and X. Hu, “Bayesian Tracking of Intracranial Pressure Signal Morphology,” Artificial Intelligence in Medicine, Accepted in October 2011.

S. Kim, M. Bergsneider, and X. Hu, “A Systematic Study of Linear Dynamic Modeling of Intracranial Pressure Dynamics,” Physiological Measurement, Vol. 32, No. 3, March 2011, pp. 319-336.

S. Kim, X. Hu, D. McArthur, R. Hamilton, M. Bergsneider, T. Glenn, N. Martin, and P. Vespa, “Inter-Subject Correlation Exists between Morphological Metrics of Cerebral Blood Flow Velocity

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and Intracranial Pressure Pulses,” Neurocritical Care, December 2010, pp. 1-9. S. Kim, F. Scalzo, M. Bergsneider, P. Vespa, N. Martin, and X. Hu, “Noninvasive Intracranial

Pressure Assessment based on Data Mining Approach using Nonlinear Mapping Function,” IEEE Transactions on Biomedical Engineering, November 2010, pp. 1-7.

F. Scalzo, S. Asgari, S. Kim, M. Bergsneider, and X. Hu, “Robust Peak Recognition in Intracranial Pressure Signals,” Biomedical Engineering Online, Vol. 9, No. 61, October 2010.

S. Kim, A. Paul, E. Wan, and J. McNames, “Multiharmonic Frequency Tracking Method using The Sigma-Point Kalman Smoother,” EURASIP Journal on Advances in Signal Processing, Vol. 2010, Article ID 467150, 2010.

S. Kim and J. McNames, “Detecting and Tracking Tremor in Binary Spike Trains using the Rectangular Model Based Extended Kalman Smoother,” Journal of Neuroscience Methods, Vol. 188, No. 1, August 2010, pp. 97-104.

L. Holmstrom, S. Kim, J. McNames, and C. Portfors, “Stimulus Design for Auditory Neuroethology using State-Space Modeling and the Extended Kalman Smoother,” Hearing Research, Vol. 247, No. 1, January 2009, pp. 1-16.

S. Kim and J. McNames, “Automatic Spike Detection Based on Adaptive Template Matching for Extracellular Neural Recordings,” Journal of Neuroscience Methods, Vol. 165, No. 2, September 2007, pp. 165-174.

b.Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners):

“Noninvasive Transcranial Doppler Intracranial Hypertension Detection,” UCLA Business of Science Center Venture Competition Grant, X. Hu (PI), 9/15/2012-6/10/2013. Role: Co-PI

“Data Mining Based Noninvasive Intracranial Pressure Assessment,” National Institute of Health Exploratory Research Grant (R21), X. Hu (PI), 2/15/2007-2/14/2009. Role: Researcher

“Modeling Intracranial Pressure Dynamics in Pediatric Traumatic Brain Injury,” Thrasher Research Funding, B. Goldstein (PI), J. McNames (co-PI), W. Wakeland (co-PI), 10/1/03-9/30/06. Role: Researcher

c. Invited research presentations outside ECU Noninvasive Intracranial Hypertension Diagnosis using Ensemble Sparse Classifiers,” Workshop for

Data Mining for Medicine and HealthCare at Conference on Knowledge Discovery and Data Mining, San Diego, CA, 21–24 August 2011.

“Noninvasive Intracranial Hypertension Detection based on Cerebral Blood Flow Velocity Waveform Alone,” International Conference on Complexity in Acute Illness, Atlanta, Georgia, 10–11 September 2010.

“Multi-Harmonic Tracker based on Sequential Monte Carlo Methods,” Annual International Conference of the IEEE Engineering in Medicine and Biology, Vancouver, BC, 20- 24 August 2008.

“Sigma-Point Kalman Filter Multi-Harmonic Tracker”, Annual International Conference of the IEEE Engineering in Medicine and Biology, Vancouver, BC, 20-24 August 2008.

d. Invited Book Chapters:

e. Peer-Reviewed Conference Proceedings D. Do, S. Kim, X. Hu, and Boyle, “In-hospital Cardiopulmonary Arrest: QRS Duration as a

Prognostic Marker of Survival to Discharge,” American College of Cardiology 61st Annual Scientific Session, Chicago, IL, 24-27 March 2012.

S. Kim, F. Scalzo, X. Hu, “Noninvasive Intracranial Hypertension Diagnosis using Ensemble Sparse Classifiers,” Workshop for Data Mining for Medicine and HealthCare at Conference on Knowledge Discovery and Data Mining, San Diego, CA, 21–24 August 2011.

S. Kim, M. Aboy, and J. McNames, “A Novel State-Space Model for Arterial Blood Pressure Signals under Mechanical Ventilation,” Annual International Conference of the IEEE Engineering in

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Medicine and Biology-Proceedings, Boston, MA, 30 August – 3 September 2011. S. Kim, M. Bergsneider, and X. Hu, “Use of Nonlinear Mapping to Improve Noninvasive Intracranial

Pressure Estimation derived from Data Mining Approach,” International Conference on Intracranial Pressure and Brain Monitoring, Tübingen, Germany, 12–16 September 2010.

S. Kim, F. Scalzo, M. Bergsneider, P. Vespa, and X. Hu, “Noninvasive Intracranial Hypertension Detection based on Cerebral Blood Flow Velocity Waveform Alone,” International Conference on Complexity in Acute Illness, Atlanta, Georgia, 10–11 September 2010.

S. Kim, M. Aboy, and J. McNames, “Pulse Pressure Variation Estimation using a Sequential Monte Carlo Method,” Annual International Conference of the IEEE Engineering in Medicine and Biology-Proceedings, Minneapolis, Minnesota, 2–6 September 2009.

S. Kim, L. Holmstrom, J. McNames, “Multi-Harmonic Tracking using Marginalized Particle Filters,” Annual International Conference of the IEEE Engineering in Medicine and Biology-Proceedings, Vancouver, BC, 20 August – 24 August 2008.

S. Kim, A. Paul, E. Wan, J. McNames, “Multiharmonic Tracking using Sigma-Point Kalman Filter”, Annual International Conference of the IEEE Engineering in Medicine and Biology-Proceedings, Vancouver, BC, 20 August – 24 August 2008.

S. Kim, J. McNames, “Tracking Intermittent Tremor Frequency using a Particle Filter,” IEEE Statistical Signal Processing Workshop, Madison, WI, 26 August – 29 August 2007.

f. Formal Reports Printed g. Patents

S. Kim, M. Aboy, and J. McNames, “Method and Apparatus for Assessment of Fluid Responsiveness,” 31 March 2011, 20110077532

5. OtherProfessional Experience

2010 – In-hospital sudden cardiac arrest prediction. Developing a proactive alert system to prevent unexpected in-hospital sudden cardiac arrest utilizing various types of clinical data

2009 – Noninvasive intracranial pressure assessment. Developing a noninvasive method to estimate intracranial pressure accurately utilizing arterial blood pressure and cerebral blood flow velocity

2006 – 2009 Rhythmicity tracking in biomedical signals. Developed an automated and robust tracking algorithm for various biomedical signals with cyclical patterns such as microelectrode recording, electrocardiogram, and arterial blood pressure

2006 – 2008 Cardiovascular dynamics of intracranial pressure for traumatic brain injury. Demonstrated the impact of hypoventilation induced hypercapnic episodes on intracranial pressure during routine mechanical ventilation management in pediatric patients with traumatic brain injury

2005 – 2007 Synchronization of essential tremor. Developed a reliable quantitative measure of synchronization between multiple sites in essential tremor

2005 – 2007 Optimization of the deep brain stimulation therapy. Studied objective methods to quantify the efficacy of the deep brain stimulation therapy

2003 – 2005 Microelectrode recording analysis. Developed an automated algorithm to detect action potentials in microelectrode recording Developed a robust algorithm to track tremorous activity in microelectrode recording related with movement disorders

2003 – 2004 Microelectrode recording image registration. Developed a reliable method to locate implanted microelectrodes via postoperative brain MRI images

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Industry Experience2005 – 2006 LSI fault isolation consultancy. Developed a fault isolation algorithm based on a step-wise

regression on a chamber level. Analyzed the end-of-line data of semiconductor manufacturing processes

2002 – 2003 Senior capstone at Intel Ronler Acres campus. Performed the power coordination analysis with EZ-power software. Assisted Intel engineers to correct errors in the coordination data sheets of FAB 20

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Faculty Information Sheet

Name: Tarek Abdel-Salam, PhD1. Rank: Associate Professor of Engineering - East Carolina University

2. Degrees: May 2003 Ph.D., Department of Mechanical Engineering, Old Dominion University,Norfolk, Virginia.March 1994 M. Sc., Department of Mechanical Engineering, Cairo University, Cairo, EgyptJuly 1988 B. Sc., Department of Mechanical Engineering, Cairo University, Cairo, Egypt

3. Teaching Experience related to proposed degree (with emphasis on the past five years)Workload Assignment: 50% teaching. 40% research, 10% service

TEACHING EXPERIENCEUndergraduate Courses Taught: Thermodynamics I/II, Fluid Mechanics, Energy Conversion, HeatTransfer, Statics, Energy Processing and Transactional Power Systems, Fluid Power, Thermal-FluidsSystems, Dynamics, Strength of Materials, Engineering Graphics, Capstone Design, FE Prep.,Engineering materials, Engineering Economics, Numerical Methods, Fluids laboratory, Thermal-Fluids lab, Undergraduate Research, and Wastewater Treatment Technology.Graduate Courses Taught: Hazmat and Environmental Management, Productivity Improvement, Computational Software for Fluids-Thermal Applications

DIRECTION OF GRADUATE STUDENT RESEARCH:Faculty Advisor/Committee Chair

Sharon Rouse, Ph.D student, Manufacturing Systems, East Carolina University. Advisory Committee member

Jimmy Linn, Ph.D, Manufacturing Systems, East Carolina University, 2011. Dissertation Committee Member:

Sanjay Garg, MS, Department of Mechanical Engineering, Old Dominion University, VA, 2012. Ravi Vedula, MS, Department of Mechanical Engineering, Old Dominion University, VA, 2011. Ajinkya S. Bhosale, MS, Department of Mechanical Engineering, Old Dominion University, VA,

2011. Kaustubh A Dharwadkar, MS., Department of Mechanical Engineering, Old Dominion University,

VA, 2008. Vaibhav Gagrani, MS, Mechanical Engineering, Old Dominion University, VA, 2008. Robert Miller, MSOS, East Carolina University, Greenville, 2007. Gaurav S. Ranzekar, Mechanical Engineering, Old Dominion University, 2005. Anurag A Chandorkar, MS, Mechanical Engineering, Old Dominion University, 2005. A. Almogbel, Ph. D., Department of Mechanical Engineering, Old Dominion University, VA, 2004. S. Hariharan, MS., Department of Mechanical Engineering, Old Dominion University, VA, 2004.

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years):

a. Publications/Scholarly Activity related to proposed degree: Tarek Abdel-Salam and Gerald Micklow, “Three-Dimensional Computational Study of the Effect of

the Inlet Conditions on Supersonic Mixing and Combustion,” IMechE, Part G, Journal of Aerospace Engineering (in print, Available online, DOI: 10.1177/0954410012438023)

Nehad Elsawaf, Tarek Abdel-Salam, and Leslie Pagliari, “Evaluation of Heat Pumps Usage in Residential Buildings in Eastern North Carolina,” International Journal of Energy and Environment, Vol. 3, No. 3, 2012, pp.399-408.

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Tarek Abdel-Salam, “Computational Study of Flow and Heat Transfer Characteristics of Circular and Rectangular Jets,” Journal of Fluids and Thermal Sciences, Vol.1, No.1, 2012, pp 19-38.

Sushil Chaturvedi, Ramamurthy Prabhakaran, Jaewan Yoon, and Tarek Abdel-Salam, “Engineering Laboratory Instruction in Virtual Environment - “eLIVE”,” Advances in Engineering Education Journal, Vol. 2, No. 4, Summer 2011, pp. 1-24 (Invited).

Gene Dixon, Tarek Abdel-Salam, and Paul Kauffmann, “Evaluation of the Effectiveness of an Energy Efficiency Program for New Home Construction in Eastern North Carolina,” Journal of Energy, Volume 35, Issue 3, March 2010, Pages 1491-1496.

Sushil Chaturvedi, Tarek Abdel-Salam, and Sai Sreedharan, “Two-Stage Direct Expansion Solar- Assisted Heat Pump for High Temperature Applications,” Journal of Applied Thermal Engineering, Vol. 29, No. 10, July 2009, pp. 2093- 2099.

Tarek Abdel-Salam, Nehad El Sawaf, and Keith Williamson, “Robotics Exploration to Enhance Information Technology Literacy in Rural Schools,” Journal of Communication and Computer, Vol.6, No.3, March 2009, pp.55-63.

Tarek Abdel-Salam, G. Micklow, and K. Williamson, "Numerical Study of Two-Dimensional Turbulent Jets Issued from Inclined Wall," International Journal of Fluid Mechanics Research(IJFMR), Vol. 35, No.1, 2008, pp 61-76.

Sushil Chaturvedi, and Tarek Abdel-Salam," Development of Building Blocks for Internet-Based Interactive Courses for Engineering Education," International Journal of Internet Education (IJIE), Vol. 11, January 2007, pp 51-57.

Sushil Chaturvedi, and Tarek Abdel-Salam, “A Web-based Module for Teaching Engineering Students About Environmental Effects of Fossil Fuel Combustion,” Computers in Education Journal. Vol. 17, No. 4, 2007.

Tarek M. Abdel-Salam and Paul J. Kauffmann, and Gary. R. Crossman, “Are Distance Laboratories Effective Tools for Technology Education?,” American Journal of Distance Education, Volume 21 No. 2, scheduled for publication in June 2007.

Tarek. M. Abdel-Salam, Paul Kauffmann, and Gary. R. Crossman,” Does The Lack of Hands-On Experience In A Remotely Delivered Laboratory Course Affect Student Learning?,” European Journal of Engineering Education. Vol. 31, No. 6, Dec. 2006.

Keith M. Williamson and Tarek Abdel-Salam, “A Moving Boundary Formulation for Recursive Plastic Heat Release during Friction Stir Welding,” Journal of Materials Processing Technology.Volume 180, Issues 1-3, 1December 2006, Pages 49-52.

S.K. Chaturvedi, T. Abdel-Salam, Sai Shrinivas S, H. M. Khan and Anurag Chandorkar, “A Web-Based Virtual Supersonic Nozzle Module as an Interactive Visualization Tool for Teaching Concepts Related to One-Dimensional Gas Dynamics” Computer in Education Journal, Vol. 16 No.2, April 2006, pp80-89.

Abdel-Salam, T. M., Tiwari, S. N., and Mohieldin, T. O., “Effects of Ramp Side Angle in Supersonic Mixing,” AIAA Journal , Vol. 41, No.6, June 2003, pp.1199-1202.

Abdel-Salam, T. M., Tiwari, S.N., and Mohieldin, T. O., “Numerical Study on Supersonic Mixing,” Virginia Journal of Science, Vol. 52, No.2, pp. 71, Summer 2001.

Tiwari, S.N., Mohieldin, T. O., and Abdel-Salam, T. M. “Numerical Study of Characteristics of Two Dimensional Plane Parallel Jets,” Virginia Journal of Science, Vol. 51, No.2, pp. 68, Summer 2000.

Elbahar, O M F; Kamel, M M; Hilal, M M; Abdel-Salam, T , “Experimental Investigation of the Structure of Air-blast Atomizer Sprays ,” Journal of Archivum Combustionis, Vol. 16, no. 1-2, 1996, pp. 55-69

b. Status of Grants & Contracts submitted related to proposed degree (including agency names, years of funding, collaborative partners): Environmental Protection Agency (EPA): Greening Coastal Vacation Rental Properties, PI,($30,000),

Oct. 2012-April 2014

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North Carolina State Energy Office: Upgrade and Save with Energy Star, Co-PI, ($200,000), April 2012-June2014.

North Carolina State Energy Office: Upgrade and Save, Co-PI, ($378.000), July 2010-June 2011. Golden Leaf- Building Engineering Pathways through Engineering Physics, and Introduction to

Engineering Courses, Co-leader ($148,472), 2010. ECU, Development of Flow Simulations Modules to Enhance Student Learning in Thermal Fluids

Systems, PI, ($7,500) July2010-June2011 Evaluation of a Wind Energy Generator, PI, ($3,600), 2009. North Carolina State Energy Office: Upgrade and Save, Co-PI , ($199,500), January 2009-June 2010. Electricities: Evaluation of the Effectiveness of an Energy Efficiency Program for New Home

Construction in Eastern North Carolina, PI, ($22,800)2006-2007. Division of Research and Graduate Studies, ECU: The Use of Triethylaluminum as a Scramjet Fuel

Conditioner and Ignition Source, PI,($15,100), 2007-2008. Division of Research and Graduate Studies, ECU: Modeling of diesel fuel sprays for direct injection

diesel engine, Co-PI,($15,192), 2007-2008. NCSU Institute for Maintenance Science and Technology (IMST): The State Of The Art In Non-

Destructive Testing (NDT) Techniques For Vertical Lift Aircraft Composite, Co-PI, ($90,000), 2007-2008.

American Society of Heating, Refrigerating and Air-Conditioning Engineers: Design and construction of a laboratory unit for testing the characteristics of axial flow fans, PI, ($2,850) 2007-2008.

North Carolina State Energy Office: Upgrade and Save, Co-PI , ($534,796), June. 2006-December 2008.

North Carolina State Energy Office: Upgrade and Save, Co-PI , ($115,000), Feb. 2006-June2006. North Carolina State Energy Office: Upgrade and Save, Co-PI , ($96,000), June2005-Feb.2006. National Science Foundation: Biomechanics and Robotics Explorations for IT Literacy and Skills in

Rural Schools, Investigator, ($1,354,847), Sept.2006-Sept.2009. North Carolina State Energy Office: Upgrade and Save, Co-PI, ($260,690), June2004-June 2005.

c. Invited research presentations outside ECU Over 50 research presentaions national and international professional meetings and conferences

Presentation at the Professional Engineers of North Carolina (PENC) Presentation at the Center For Sustainable Tourism Open House (invited) Presentations at the American Society of Mechanical Engineering Conferences (ASME) Presentations at the annual conferences of the American Society of Engineering Educators

(ASEE) Presentations at the American Institute of Aeronautics and Astronautics conferences (AIAA) Presentations at the Society of Automotive Engineers conferences (SAE) Presentations at Virginia Academy of Science Annual Meetings. Presentation at the International Conference of Internet Based Learning ICT-Learn. . Presentations at the ASEE/IEEE Frontiers in Education Conferences (FIE). Presentation at the 8th International Conference for Mechanical Power Engineering

d. Invited Book Chapters: Tarek Abdel-Salam, Numerical Studies On Supersonic Mixing and Combustion Phenomena, VDM

Verlag, 2009, ISBN 978-3-639-20188-8. Sushil Chaturvedi, Tarek Abdel-Salam, and Prashanth Muthoju, “a Computer-Based Active

Learning Tool for Simulating Performance of Steam Power Cycles,” INNOVATIONS 2009: World Innovations in Engineering Education and Research, Chapter 12, ISSN 1553-9911, ISBN 978-0-9741252-9-9, August 2009.

Sushil Chaturvedi, Tarek Abdel-Salam, “Virtual Assembly” – A Web-Based Student Learning Tool for Thermodynamics Concepts Related to Multistaging in Compressors and Turbines INNOVATIONS

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2008: World Innovations in Engineering Education and Research, Chapter 36, ISSN 1553-9911 , ISBN 978-0-9741252-8-2, July 2008.

Sushil Chaturvedi, Tarek Abdel Salam, Prashanth Muthoju , Sai Shrinivas and Vaibhav Gagrani, “Mapping of a Thermo-fluids Laboratory Experiment into a Web-based Virtual Experiment for Application as a Prelab Practice Tool” INNOVATIONS 2007: World Innovations in Engineering Education and Research, Chapter 28, ISSN 1553-911, ISBN 978-0-9741252-6-8, August 2007.

Sushil Chaturvedi, Tarek Abdel-Salam, and Sai Sreedharan “A Web-Based Interactive Student Learning Tool for Visualization, Simulation and knowledge Integration in the Undergraduate Thermodynamics Course,” INNOVATIONS 2006: World Innovations in Engineering Education and Research, Chapter 27, ISBN 0-9741252-5-3, July 2006

e.Peer-Reviewed Conference Proceedings Joshua Wheeler and Tarek-Abdel Salam, “A Three-Dimensional Numerical Study of Biodiesel Flow

Characteristics in Diesel Injectors,” State of North Carolina Undergraduate Research and Creativity Symposium, November 2011.

Srikanth Pidugu, Tarek Abdel-Salam, “Modeling of Taylor Flows in T-junction Microchannel with Mixing Chambers,” Proceedings of the 11th ASME International Symposium on Numerical Methods for Multiphase Flow, AJK2011-04034, July 24-29, 2011, Hamamatsu, Shizuoka, Japan.

Tarek Abdel-Salam and Srikanth Pidugu, “Mixing Characteristics of a Two-Phase Flow (gas-liquid) in a Microchannel Mixer,” Proceedings of the International Conference on Nanochannels, Microchannels and Minichannels, ICNMM 2011-58239, June 2011.

Tarek Abdel-Salam, “Numerical Study of Flow and Heat transfer Characteristics of Impinging Jets,” Proceedings of the ASME 2010 International Mechanical Engineering Congress and Exposition, paper # IMECE2010-40205, November 2010.

Tarek Abdel-Salam, Srikanth Pidugu, and Tuba Byrakhtar, “Two-Dimensional Numerical Study of Two-phase Flow (gas-liquid) in a Microchannel Mixer” Proceedings of the ASME 2010 International Mechanical Engineering Congress and Exposition, paper # IMECE2010-39830, November 2010.

Tarek Abdel-Salam, “Two Dimensional Simulation of Flow and Heat Transfer Charactristics of Turbulent Jets,” Proceedings of the 14th ASME International Heat Transfer Conference, Manuscript No. IHTC14-23150, August 2010.

Srikanth Pidugu, Tarek Abdel-Salam, and Tuba Byrakhtar, “Flowfield Analysis in T-Junction Microchannel with Bubble Formations” Proceedings of the International Conference on Nanochannels Microchannels and Minichannels, ICNMM 2010-30786, August 2010.

Sushil Chaturvedi, Tarek Abdel Salam, “Transformation of a Physical Experiment into a Virtual Experiment for Web applications,” Proceedings of the 8th international Conference on Web-based Education, WBE, March 2009, paper No.644-019, Phuket, Thailand.

Tarek Abdel-Salam and Gerald Micklow" Study Of Mixing Characteristics Of Rectangular Turbulent Jets ," Proceedings of the 2008 ASME/JSME Fluids Engineering Summer Conference, FEDSM2008, Jacksonville, FL, August 2008.

Gerald J. Micklow, Krishna Ankem, and Tarek Abdel-Salam,"A Comprehensive Fuel Spray Model for High Pressure Fuel Injectors," Proceedings of the ASME Turbo-Expo 2008, GT2008-50457, Berlin Germany, June 2008.

Gerald Micklow, B. Murphy and Tarek Abdel-Salam, “An Efficient Thermodynamic Cycle Analysis for the Performance Prediction of Fuel Inducted Spark Ignition Engines,” Proceedings of the 2008 SAE World Congress, paper # 2008-01-0289, April 2008.

G. Micklow, K. Ankem , and T. Abdel-Salam, “Fuel Spray Modeling for Direct Injection Compression Ignition Engine Configurations,” Proceedings of the 2008 SAE World Congress, paper # 2008-01-0947, April 2008.

Tarek Abdel-Salam and Gerald Micklow, “Numerical Investigation of the Effect of the Inlet Conditions on Supersonic Mixing and Combustion,” The 46th AIAA Aerospace Sciences Meeting and Exhibit, AIAA Paper No. 2008-93 Reno, Nevada, January 2008.

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Sushil Chaturvedi, Tarek Abdel-Salam and Omkar Kasinadhuni, "Virtual Assembly: A Web-Based Student Learning Tool for Thermodynamics Concepts Related to Multistaging in Compressors and Turbines," Proceedings of the International Conference of Engineering Education, ICEE 2007, Coimbra, Portugal, September 2007.

Tarek Abdel-Salam, "Numerical Study of Two-Dimensional Co-Flowing Turbulent Jets," Proceedings of the 2007 ASME/JSME Fluids Engineering Summer Conference, FEDSM2007, San Diego, CA, July-August 2007.

Paul Kauffmann, Tarek Abdel-Salam, and John Garner, “Predictors of Success in The First Two Years: A Tool For Retention,” Proceedings of the ASEE 2007 Annual Conference, June 2007.

Gerald Micklow, Sai Kotha , and Tarek Abdel-Salam, "Three Dimensional Bluff Body Aerodynamic Analysis for Automotive and Automotive Racing Applications," Proceedings of the SAE-Motorsoprts Engineering Conference, Dearborn, Michigan, December 2006. (Received Best Paper Award)

Sushil Chaturvedi, Tarek Abdel-Salam, Omkar Kasinadumi, and Sai Sreedharan, “A Web-based Module for Teaching Engineering Students About Environmental Effects of Fossil Fuel Combustion,”Proceedings of 2006 ASEE Global Colloquium on Engineering Education, October 2006.

Tarek Abdel-Salam, Gerald Micklow, and Keith Williamson, “Numerical Study of Two-Dimensional Turbulent Jets,” Proceedings of FEDSM2006. (2006 ASME Joint U.S. - European Fluids Engineering), July 2006.

Ranjeet Agarwala, Tarek Abdel-Salam, “Development and Implementation of a Rapid Prototyping Course,” Proceedings of the International Conference of Agile Manufacturing, July 2006

Keith M. Williamson, Gene Dixon, Paul Kauffmann, and Tarek Abdel-Salam, “Developing a Fundamentals of Engineering (FE) Based Competency Module for a Freshman Engineering Course,” Proceedings of the ASEE 2006.

Ranjeet Agarwala, Tarek Abdel-Salam, and Craig Sanders, “A New Undergraduate Course in Electromechanical Systems for Industrial Engineering Technology,” Proceedings of the ASEE 2006.

Craig Sanders, Tarek Abdel-Salam , and Kathryn Griffin, “Choices: Educational Delivery Options For The Working Professional And Traditional Student,” Proceedings of ASEE-CIEC, January 2006.

Tarek Abdel-Salam, Paul Kauffmann, and Keith Williamson, “A Case Study: DO High School GPA/ SAT Scores Affect The Performance Of Freshmen Engineering Students?” Proceedings of the 35 th ASEE/ IEEE Frontiers in Education (FIE), October 2005.

Tarek Abdel-Salam, Keith Williamson, and Paul Kauffmann, “Using the Web to Invite the Local Community Into the Engineering Classroom” Proceedings of the 35th ASEE/ IEEE Frontiers in Education October 2005. (Received ASEE Faculty Fellowship)

Tarek Abdel-Salam, Paul Kauffmann, and Keith Williamson, “Do On-Campus Students Write Better than Their Distance Learning Counterparts in Engineering and Technology Fields?” Proceedings of the American Society of Engineering Education (ASEE), June 2005.

Paul Kauffmann, Tarek Abdel-Salam, Keith Williamson, and Carol Considine, “Privatization Initiatives: A Source for Engineering Economy Case Studies,” Proceedings of the American Society of Engineering Education (ASEE), June 2005.

Chaturvedi, S. K., Bawab, S., Akan, H., and Abdel-Salam, T., “ Development of a Methodology to Visualize and conduct a Physical Experiment as a Web-based Virtual Experiment,” Proceedings of the Fourth IASTED International Conference on We-Based Education, Grindelwald, Switzerland, February 2005.

Tarek Abdel-Salam, and Carson, R., “Investigation of Mixing and Flow Characteristics in a Dual- Mode Combustor,” 38th AIAA Thermophysics Conference, AIAA Paper No. 2004-2384, Portland, Oregon, June 2004.

Tarek Abdel-Salam, and Tiwari, S. N., “Mixing Characteristics of Two-Dimensional Parallel Jets,” The 42th AIAA Aerospace Sciences Meeting and Exhibit, AIAA Paper No. 2004-1270 Reno, Nevada, January 2004.

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Crossman, R. G., and Abdel-Salam, T. M., “A CD-ROM Based Laboratory in Fluid Mechanics, Assessment and Evaluation,” Proceeding of Frontiers in Education Conference FIE 2003, Westminster, Colorado, Nov. 2003.

Chaturvedi, S. K., Akan, O. A., bawab, S., Abdel-Salam, T. M., and Manjunath, S., “A Web-Based Multi-Media Virtual Experiment,” Proceeding of Frontiers in Education Conference FIE 2003, Westminster, Colorado, Nov. 2003.

Tarek Abdel-Salam, Tiwari, S. N., and Mohieldin, T. O., “Study of Supersonic Combustion Characteristics in a Scramjet Combustor,” 16 AIAA Computational Fluid Dynamics Conference, AIAA Paper No. 2003-3550, Orlando, Florida, June 2003.

Chaturvedi, S. K., Akan, O. A., Abdel-Salam, T. M., and Priyadershini, A., “Performing Interactively a Thermo-Fluids laboratory Experiment in the Virtual Domain,” Proceeding of the 2003 ASEE Annual Conference and Exposition, Nashville, Tennesee, June 2003.

Abdel-Salam, T. M., Tiwari, S. N., and Mohieldin, T. O., “Investigation of Mixing and Flow Charactristics in a Dual-Mode Combustor,” The 41th AIAA Aerospace Sciences Meeting and Exhibit, AIAA Paper No. 2003-0372 Reno, Nevada, January 2003.

Abdel-Salam, T. M., Tiwari, S. N., and Mohieldin, T. O., “Numerical Study of a Dual-Mode Combustor Flowfield,” 36th AIAA Thermophysics Conference, AIAA Paper No. 2002-2889, Saint Louis, MO, June 2002.

Abdel-Salam, T. M., Tiwari, S. N., and Mohieldin, T. O., “Three-Dimensional Numerical Study of a Scramjet Combustor,” The 40th AIAA Aerospace Sciences Meeting and Exhibit, Paper No. 2002-0805 Reno, Nevada, January 2002.

Tiwari, S.N., Taha, A. A., Abdel-Salam, T. M., and Mohieldin, T. O., “Supersonic Mixing and Combustion Characteristics in Scramjet Engines,” Proceeding of the 15th International Symposium on Airbreathing Engines (XV ISABE), ISABE Paper No. 2001-1002, September 2001, Bagalore, India

Abdel-Salam, T. M., Tiwari, S.N., and Mohieldin, T. O., “Analysis of a Dual-Mode Scramjet Combustor,” 37th AIAA/ASME/SAE/ASEE Joint Propulsion Conference, AIAA Paper No. 2001- 3194, July 2001.

Abdel-Salam, T. M., Tiwari, S.N., and Mohieldin, T. O., “Dual-Mode Flowfield in a Scramjet Combustor,” 35th AIAA Thermophysics Conference, AIAA Paper No. 2001-2966, June 2001.

Tiwari, S. N., Abdel-Salam, T. M., Taha, A. A., and Mohieldin, T. O., “Supersonic Mixing and Combustion in Scramjet Combustors Using Unstructured Grids,” Proceedings of the 9th Annual Conference of the CFD Society of Canada, Paper No. 2001-066, Waterloo, Ontario, Canada, May 2001.

Abdel-Salam, T. M., Tiwari, S.N., and Mohieldin, T. O., “Study of Dual-Mode Flowfield In Scramjet Combustors,” 39th Aerospace Sciences Meeting , AIAA Paper No. 2001-0380, January 2001.

Abdel-Salam, T. M., Tiwari, S.N., Mohieldin, T. O., and S.K. Chaturvedi., “Numerical Study of the Effects of Ramp Swept Angle in Supersonic Mixing and Combustion,” Proceeding of the 34th National Heat Transfer Conference, ASME Paper No. 2000-12028, Pittsburgh, PA, August 20-22, 2000 (On CD-Rom).

Tiwari, S. N., Abdel-Salam, T. M., and Mohieldin, T. O., “Characteristics of Two-Dimensional Turbulent Plane Parallel Jet Flows,” NASA Langley Research Center, Hampton, Virginia, NASA Cooperative Agreement NCC 1-349, August 2000.

Abdel-Salam, T. M., Tiwari, S. N., Chaturvedi, S.K., and Mohieldin, T. O., “Mixing and Combustion in Scramjet Combustor with Raised and Relieved Ramps,” 36th AIAA/ASME/SAE/ASEE Joint Propulsion Conference, AIAA Paper No. 2000-3709, July 2000.

Abdel-Salam, T. M., Tiwari, S.N., and Mohieldin, T. O., “Effects of Ramp Swept Angle In Supersonic Mixing,” 21st AIAA Fluids 2000 Conference, AIAA Paper No. 2000-2377, June 2000.

Mohieldin, T. O., Abdel-Salam, T. M., and Tiwari, S.N. “Numerical Study of Supersonic Mixing Using Unstructured Grid,” Hyper-X program Office, NASA Langley Research Center, Hampton, Virginia, HX Report HX-781, March 2000.

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Tiwari, S.N., Mohieldin, T. O., and Abdel-Salam, T. M., “Numerical Study of Interaction of Two- Dimensional Parallel Jets,” 38th Aerospace Sciences Meeting, AIAA Paper No. 2000-0816, January 2000.

Mohieldin, T. O., Abdel-Salam, T. M., and Tiwari, S.N., “Numerical Study of Supersonic Mixing and Combustion Using Unstructured Grid,” 38th Aerospace Sciences Meeting , AIAA Paper No. 2000- 0439, January 2000.

Elbahar, O. F., Abdel-Salam, T. M., Kamel, M. M., and Hilal, M. M., “Experimental Investigation of the Structure of Air-Blast Atomizer Sprays,” Proceeding of the Eighth International Conference for Mechanical Power Engineering, Alexandria, Egypt, April 1993, Vol. 1, pp. 133-147.

f. Formal Reports Printed Upgrade and Save, October 2011. Evaluation of a Vertical Wind Turbine, November 2009. The State of the Art in Non-Destructive Testing (NDT) Techniques for Vertical Lift Aircraft Composite, March 2009. Design and Construction of a Laboratory Unit for Testing the Characteristics of Axial Flow Fans, May 2008. Evaluation of the Effectiveness of an Energy Efficiency Program for New Home Construction in Eastern North Carolina, January 2008. Heat Pumps in Manufactured Homes, July 2005.

5.Other:INDUSTRIAL EXPERIENCE 04/00 - 03/01 Senior Engineer Industrial Assessment Center, Old Dominion University, Norfolk, VA. 10/95 –8/97 Senior Environmental Engineer Energy Conservation and Environment Project (US project),

Development Research and Technological Planning Center, Cairo University, Cairo, Egypt

PROFFESSIONAL SERVICE ACTIVITIES: Founding Faculty and Advisor of ECU’s Student Branch of the American Society of Mechanical

Engineers (ASME) 2010-present Founding Faculty and Advisor of ECU’s Student Branch of the American Society of Heating,

Refrigerating and Air Conditioning Engineers (ASHRAE) 2007-present

Review Panel Department of Defense, the 2012 National Defense Science and Engineering Graduate Fellowship

(NDSEG). Arlington, VA, February 2012. NSF-Research Initiation Grants in Engineering Education Program (RIGEE), Arlington, VA, May-June

2011. NASA Aeronautics Scholarship Program, Washington D.C., February 2011.

Conference Session Organizer Heat Transfer and Advances in Thermal & Fluid Science, Society of Automotive Engineers, The 2013

Powertrain, Fuels & Lubricants Conference, Seoul, Korea, October 2013. Fuel Injection and Sprays (Numerical and Experimental sessions), Society of Automotive Engineers, SAE

World Congress, Detroit, April 2013. Heat Transfer and Advances in Thermal & Fluid Science, Society of Automotive Engineers, SAE World

Congress, Detroit, April 2013. Cold Start and Transients, Society of Automotive Engineers, Powertrains Fuels & Lubricants Conference,

Malmo, Sweden September 2012. Fuel Injection and Sprays (Numerical and Experimental sessions), Society of Automotive Engineers, SAE

World Congress, Detroit, April 2012. Heat Transfer and Advances in Thermal & Fluid Science, Society of Automotive Engineers, SAE World

Congress, Detroit, April 2012.

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Compression Ignition Combustion, Society of Automotive Engineers, Intl Powertrain, Fuels & Lubricants International Meeting, Tokyo, Japan, August 2011.

Fuel Injection and Sprays (Numerical and Experimental sessions), Society of Automotive Engineers, SAE World Congress, Detroit, April 2011.

Numerical and Experimental Heat Transfer, ASME- International Mechanical Engineering Conference and Exposition, Vancouver, British Columbia, November 2010.

Kinetically-Controlled CI Combustion, Society of Automotive Engineers, Intl Powertrain, Fuels & Lubricants, Brazil, May 2010.

Fuel Injection and Sprays (Numerical and Experimental sessions), Society of Automotive Engineers, Intl Powertrain, Fuels & Lubricants, Brazil, May 2010.

Diesel Fuel Injection and Sprays(Numerical and Experimental sessions), Society of Automotive Engineers, SAE World Congress, Detroit, April 2010.

Direct Injection and Sprays (Numerical and Experimental sessions), Society of Automotive Engineers, Powertrains, Fuels & Lubricants Conference in Florence, Italy, June 2009.

Diesel Fuel Injection and Sprays (Numerical and Experimental sessions), Society of Automotive Engineers, SAE World Congress, Detroit, April 2009.

Conference Session Chair ECE session, American Society of Engineering Education, San Antonio, TX, June 2012. Fuel Injection and Sprays (Numerical and Experimental sessions), Society of Automotive Engineers, SAE

World Congress, Detroit, April 2012. Heat Transfer and Advances in Thermal & Fluid Science, Society of Automotive Engineers, SAE World

Congress, Detroit, April 2012. Fuel Injection and Sprays (Numerical and Experimental), Society of Automotive Engineers, SAE World

Congress, Detroit, April 2011. Numerical and Experimental Heat Transfer session, ASME- International Mechanical Engineering

Conference and Exposition, Vancouver, British Columbia, November 2010. Diesel Fuel Injection and Sprays (Numerical and Experimental), Society of Automotive Engineers, SAE

World Congress, Detroit, April 2010. Diesel Fuel Injection and Sprays (Numerical and Experimental), Society of Automotive Engineers, SAE

World Congress, Detroit, April 2009.Editorial Board International Journal of Engineering (2012-present) Journal of Fluids and Thermal Sciences (2010-present) Journal of Mechanical, Aerospace, and Industrial Engineering (2010-present).Editorial Advisory Board International Journal of Energy and Environment (2009-present) Scientific Journals International (2010-present)Reviewer Journal of Fluids Engineering, 2010-present. Journal of Mechanical Engineering, Institution of Mechanical Engineers, Part C. (2010-present) Journal of Aerospace Engineering, Institution of Mechanical Engineers, Part G (2010-present) Journal of Process Mechanical Engineering, Institution of Mechanical Engineers, Part E (2010- present) Journal of Engineering Technology (JET), (2009-present) Journal of Zhejiang University- Science, Part A (Energy) (2008-present) Journal of Applied Energy(2005-presesnt) Journal of Applied Thermal Engineering. (2004-present) Journal of Energy.(2004-present) International Network for Engineering Education and Research “iNEER” (2005-present) IAJC-IJME International Conference SAE World Congress (2007-present) Frontiers in Education Conference

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ASEE Annual Conference Wiley and Sons Publisher McGraw Hill Company Prentice Hall Publisher Member of the focus group on engineering mechanics, John Wiley and Sons, June 2005. Member of the focus group on engineering Thermodynamics, John Wiley and Sons, October 2005.

UNIVERSITY SERVICEUniversity Wide Performance Review Advisory Panel, 2013. University Research Council, 2011-2013. Faculty Senate, 2009-2011. University Undergraduate Curriculum Committee, 2009-2010. University Libraries Committee, 2009-2010. Visual Arts Committee, 2009-2010. International Faculty and Staff Committee, 2006-present Research and Creative Activities Committee, 2005-2008. Affordable Computers for Everyone (ACE), 2005-present

College Wide College Scholar Teacher Award, Chair 2012-2013. College Elections Committee, Chair, 2011-2013. College Graduate Curriculum Committee, 2012-present. College Scholar Teacher Award, 2009-2012. College Technology Committee, 2004-Present. College Ad-Hoc Graduate Committee, 2007-presnet College Laboratory Committee, Chair, 2005- 2006 Department of Construction Management, Tenure Committee, 2012-2014. Department of Construction Management, Personnel Committee, 2012-2014. Department of Construction Management, Promotion Committee, 2012-2014

Department of Engineering Department of Engineering, Mechanical Engineering Concentration, Program Coordinator, 2012-present. Department of Engineering, Personnel Committee, Chair, 2012-2013. Department of Engineering, Capstone Committee, 2012-present. Department of Engineering, Electrical Engineering Search Committee, Chair, 2012. Department of Engineering, Biomedical Engineering Search Committee, Chair, 2011. Department Engineering Chair Search Committee, 2009. Department of Engineering, Tenure and Promotion Committee, 2009-present. Department of Engineering, Personnel Committee, 2009-present. Department of Engineering, K-12 and CC Marketing and Outreach, 2009. Department of Engineering, Admission Committee, 2007-2010. FAR Rubric and Promotion / Tenure Guidelines Committee, 2007-present. Student Life Committee, 2006-2007. Department of Engineering, Grants Committee, 2006-2007. Department of Engineering, Assessment Committee, 2005-present. Department of Engineering, Core and Curriculum committee, 2005-present. Engineering Committee, 2004- 2005 Department of Technology Systems, Technology Assessment Committee, 2004- 2005 Department of Technology Systems, Awards Committee, 2003- 2004

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Faculty Information Sheet

Name: Ricky T. Castles1. Rank: Assistant Professor of Engineering - East Carolina University

2. Degrees: Ph.D. Computer Engineering, May 2010Virginia Polytechnic Institute and State University, Blacksburg, VirginiaDissertation: A Knowledge Map-Centric Feedback-Based Approach to Information Modeling and Academic Assessment, Co-Advisors: Dr. Pushkin Kachroo (ECE) and Dr. Vinod Lohani (Engineering Education)Graduate Certificate in Human Computer Interaction, May 2009, Virginia Polytechnic Institute and State University, Blacksburg, VirginiaMS in Industrial and Systems Engineering, May 2008, Virginia Polytechnic Institute and State University, Blacksburg, VirginiaMS in Computer Engineering, May 2006, Virginia Polytechnic Institute and State University, Blacksburg, VirginiaBS in Computer Engineering, May 2003, Virginia Polytechnic Institute and State University, Blacksburg, Virginia

3. Teaching Experience related to proposed degree (with emphasis on the past five years):Workload Assignment: 60% teaching. 30% research, 10% serviceEast Carolina University 2011 – present - Teaching Assistant Professor 2010 – 2011 - Teaching Instructor

EENG 2410- Digital CircuitsThe first electrical engineering course offered at East Carolina University. Emphasis on Boolean logic, digital logic minimization techniques, and hardware implementation including both combinational and sequential logic design.

ENGR 2514- Circuit AnalysisA junior level first course in circuit theory emphasizing AC and DC circuit analysis techniques.

MENG 4350- Electromechanical System DesignA senior level technical elective focusing on the integration of electrical and mechanical systems. Emphasis is placed upon digital logic, analog signal conditioning, microcontroller programming, motor control, pneumatic and hydraulic systems, and hands-on analysis and design experience. .

ENGR 1000- Introduction to EngineeringA first semester freshman-level seminar course introducing the engineering profession, engineering problem solving, engineering design, the various engineering opportunities at East Carolina University, and advice for becoming a successful student.

ENGR 1014- Introduction to Engineering (2011) ENGR 1016- Intro to Engineering Design (2012)A second semester hands-on freshman-level course introducing electronics, robotics, sensors, problem solving, and the engineering design method.

ENGR 2050- Computer Applications in EngineeringA second semester freshman-level course introducing advanced applications of Microsoft Excel and an introduction to computer programming using Matlab.

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ENGR 1012- Engineering GraphicsA first semester freshman level introductory engineering course focused on graphics communication. The course covers both traditional hand drawing techniques in 2D and 3D and the use of SolidWorks solid modeling software.

Virginia Polytechnic Institute and State University, Blacksburg, Virginia2003 – 2010 - Graduate Teaching Assistant

ENGE 1024- Engineering ExplorationA first semester freshman level introductory engineering course required for all engineering majors. The course introduces the various engineering disciplines and the fundamentals of professional practice. Additional course topics include teamwork, professionalism, ethics, design, globalization, sustainability, graphic communication, problem solving, flowcharting, and introductory programming. The course includes a weekly lecture and a weekly hands-on workshop. Students also work in teams on an eight-week sustainable energy design project. In the fall semester this course has an enrollment of nearly 1,500 students while in the spring there is an enrollment of approximately 180 students.

ECE 1574- Engineering Problem Solving with C++A second semester freshman level introductory object-oriented programming course for Electrical and Computer Engineering majors.

ECE 3534- Microprocessor System DesignA junior level course for Electrical and Computer Engineering majors involving intensive machine level programming using the Motorola 68HC11 microcontroller. Students complete various labs involving both hardware and software development. This is the ECE in-major writing intensive course.

ECE 2504- Introduction to Computer EngineeringA sophomore level course in which Electrical and Computer Engineering students learn the fundamentals of computer engineering including Boolean logic, integrated circuits, and machine-level programming. Students complete a series of labs involving digital logic design, wiring of digital circuits, and assembly programming.

ECE/ME 4734- MechatronicsA senior level design course in which Electrical, Computer, and Mechanical Engineering students complete a series of labs involving programming a PIC microcontroller using assembly, control of a motor, and reading in data from an A/D converter. The course culminates with students developing a mechatronic design project in teams.

4. Scholarly & Professional Activities related to proposed degree (with emphasis on the past five years)

Publications/Scholarly Activity related to proposed degree:

Journal Articles1. M.C. Hand, M. A. Rose, M. E. Pokorny, R. T. Castles, F. Watkins, M. K. Kirkpatrick, M. Swanson, M.

Engelke, R. Moore, W. Wu, K. Chen (2013). “Pilot testing the Augmentech Body Position Sensor on the morbidly obese patient.” in Applied Nursing Research, (In Press).

2. R. T. Castles, T. Zephirin, V. K. Lohani, P. Kachroo, “Design and Implementation of a Mechatronics Initiative in a Large First Semester Engineering Course” in IEEE Transactions on Education, Vol 53, Issue 3, pp. 445-454, August 2010.

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3. V. K. Lohani, R. Castles, J. Lo, H. Griffin, “Tablet PC Applications in a Large Engineering Program,” in Computers in Education Journal, Vol. XVIII, No. 2, pp. 52-63, April-June 2008.

Conference Proceedings- Peer Reviewed Full Papers1. R. Castles, L. Mellish, M. Frank, K. De Urquidi, D. Majewski, W. Howard, J. Foeller, O. Griffin, E.

Coghill, J. Geissler “Use of an Early Alert Warning System to Guide Students Toward Success in Statics” in ASEE Annual Conference and Exposition, Atlanta, GA June 23-26, 2013. (Abstract accepted, full paper acceptance pending)

2. R. Castles, P. Kachroo, V. Lohani “Quantifying the Distance Between Student Knowledge Maps Using the Principles of Topology” in ASEE Annual Conference and Exposition, Atlanta, GA June 23-26, 2013. (Abstract accepted, full paper acceptance pending)

3. P Kauffmann, S. Archava, R. Castles, H. Ries, S. Sullivan, K. DeUrquidi “Factors Impacting Poor Performance in Pre-Calculus” in ASEE Annual Conference and Exposition, Vancouver, BC, Canada, June 26-29, 2011.

4. R. Castles, V. K. Lohani, P. Kachroo “Utilizing Software-Generated Concept Maps Based on Customized Concept Inventories to Illustrate Student Learning and Knowledge Gaps” in ASEE Annual Conference and Exposition, Louisville, KY, June 20-23, 2010.

5. V. Lohani, R. Castles, G. Riggins “A Workshop for Indian Engineering Faculty Under the Indo-US Collaboration in Engineering Education” in ASEE Annual Conference and Exposition, Louisville, KY, June 20-23, 2010.

6. R. Castles, V. K. Lohani, and P. Kachroo, " Utilizing Hands-On Learning to Facilitate Progression Through Bloom’s Taxonomy Within the First Semester" in IEEE Frontiers in Education, San Antonio, TX, October 18-21, 2009.

7. R. Castles and V. K. Lohani, "A paradigm for comprehensive concept map-based modeling of student knowledge," in American Society for Engineering Education Annual Conference and Exposition, Austin, TX, June 14-17, 2009.

8. R. Castles, J. Lo, V. K. Lohani, E. Scott, “Tablet PC based electronic grading system in a large first year engineering course” in American Society for Engineering Education Annual Conference and Exposition, Austin, TX, June 14-17, 2009.

9. R. Castles, V. K. Lohani, and P. Kachroo, "Knowledge maps and their application to student and faculty assessment," in IEEE Frontiers in Education, Saratoga Springs, NY, October 22-28, 2008.

10. V. K. Lohani, R. Castles, A. Johri, D. Spangler, D. Kibler “Analysis of tablet PC based learning experiences in freshman to junior level engineering courses” in ASEE Annual Conference and Exposition, Pittsburgh, PA, June 22-25, 2008.

11. V.K. Lohani, R. Castles, J. Lo, O. H. Griffin, “Tablet PC applications in a large engineering program” in ASEE Annual Conference and Exposition, Honolulu, HI, June 24-27, 2007.

Posters

1. M. Hand, M. Kirkpatrick, M. Pokorny, M. Rose, F. Watkins, R. Castles, M. Engelke, R. Moore, Q. Wu, K. Chen “Pilot Testing the Augmentech Body Position Sensor on the Morbidly Obese Patient” in 21st Annual Collaborative Nursing Research Day, Greenville, NC February 24, 2012.

2. R. Castles “Using Detailed Graphical Models to Advance Personalized Learning” in National Academy of Engineering Regional Summit on the Grand Challenges, Phoenix, AZ, April 8-9, 2010

3. 1st place winner in regional student design poster contest

4. Presented poster and video at National NAE Summit on the Grand Challenges, Los Angeles, CA, October 6-8, 2010

5. R. Castles “Coupling Concept Maps with Concept Inventories to Perform Detailed Student Learning Assessment.” NSF Engineering Education Division Awardees Conference, Reston, VA, Jan 31-Feb 2, 2010

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6. R. Castles “A Knowledge Map-Centric Feedback-Based Approach to Personalized Learning” in National Academy of Engineering Summit on the Grand Challenges, Durham, NC, March 1-3, 2009

5. OtherExtramural Research Grants

S. Ganter, R. Castles, M. Oros, C. Schwartz, M. Sprague “ECU Connects! Expanding the STEM Pipeline through long-term partnerships between schools and industry” NSF Math Science Partnership Grant Program. $1,378,264, 36 months 2013-2016, funding pending

Graduate Research work and conference travel sponsored in part by NSF Department Level Reform Grant 0431779

Industry Experience

2002 – present - Imaging Science Research, Inc, Burke, VASoftware Consultant Developed radar system software to configure a custom data acquisition card Developed Graphical User Interface (GUI) software Developed multithreaded acquisition software Converted Fortran 77 code to modern language

2001 - Navy Center for Applied Research in Artificial Intelligence –Washington, D.C., Summer Intern Developed computer vision algorithms for autonomous aerial vehicle navigation

Professional Affiliations

IEEE - member 2002-2003, 2009-Present

American Society for Engineering Education Member 2008-Present Educational Research Methods Division Computers in Education Division Electrical and Computer Division Information Systems Division

eLearning Guild 2005-Present

Associate Member, Tau Beta Pi, Engineering Honor Society 2001-Present

National Society of Collegiate Scholars 2000-Present

Professional Service

AdvisingAcademic Advisor, August 2010-presentAdvise half of the ECU engineering students (~200 students)

MentorFaculty Mentor for High School Graduation Project, Fall 2010 and 2011-Introduced 2 high school students to robotic theory and application

International WorkshopIndo-US Collaboration for Engineering Education, July 2009-Invited to India to present hands-on learning initiatives used at Virginia Tech in the first semester engineering program

Invited PanelistPanel on Teaching in Engineering- 18th Annual GTA Workshop-August 19, 2008How GTAs Can Affect Student Learning- September 17, 2008

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ReviewerInvited Reviewer IEEE Transactions on Education- 2009-present-Reviewed three articles in the area of mechatronics education

Research PresentationsHour long research presentation on my research work to Sue Kemnitzer, deputy division director for education, National Science Foundation- January 13, 2009Invited lecture on my research work to Dr. Terry Wildman’s graduate level advanced educational psychology class

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Curriculum VitaeAmanda K. Funai, Ph.D.

PERSONAL INFORMATION Name: Amanda Kay Funai Email: amanda.funai@gmail.com Address: 8056 Venetian Dr. Apt.8 Phone: (734) 945-1800 St. Louis, MO, 63105 Citizenship: United States

EDUCATION 2011 Ph.D. University of Michigan, Electrical Engineering, GPA: 7.82/9.00 (A+:9)

Mentor: Jeffrey Fessler, Co-Mentor: Douglas Noll Dissertation Title: “Regularized Estimation of Main and RF Field Inhomogeneity and Longitudinal Relaxation Rate in Magnetic Resonance Imaging”

2007 M.S. University of Michigan, Electrical Engineering 2005 B.S. Northeastern University, Electrical and Computer Engineering, GPA: 4.00/4.00

AWARDS 2010 Margaret Ayers Host Award, University of Michigan 2007-2010 National Science Foundation (NSF) Graduate Research Fellowship 2005-2007 Rackham College of Engineering Fellowship, University of Michigan 2005 Valedictorian, Northeastern University 2005 Flag Marshall, College of Engineering, Northeastern University 2005 President’s Award, Northeastern University 2004 Junior Ring Award, Northeastern University 2003 Outstanding ECE Middler, Northeastern University 2003 William Rand Award, Northeastern University 2002 Outstanding ECE Sophomore, Northeastern University 2002 Women in Engineering Grant Recipient, Northeastern University 2001 Outstanding ECE Freshman, Northeastern University 2001 Phi Kappa Phi Award, Northeastern University 2000-2005 Ell Scholar, Northeastern University 2000-2005 Dean’s List, Northeastern University 2000 Honors Program, Northeastern University

PROFESSIONAL EXPERIENCE 2006-2011 Graduate Research Fellow, Fessler Lab, EECS Department, University of Michigan

Develop new statistically based iterative estimators for MRI main and RF field maps as well as T1 mapping. Use statistical methods and Matlab to show the strength of these new estimators.

2004 Research Assistant/Programmer, Dy Lab, ECE Department, Northeastern University Develop software in C++ and Java for visualization and interactive feature selection for unsupervised data.

2003-2004 Hardware Design Co-op, Sun Microsystems, Burlington, MA Test and help finish a block on the Sparc Chip. Test and help resolve timing, electromigration, physical, and extraction issues. Resolve layout and pin issues and implement new level of hierarchy. Schematic entry. Critical Path simulations and modeling. Writing scripts and html. Learn basics of SPARC architecture and implementation methodology.

2002 Engineering Co-op, TEK Microsystems, Burlington, MA

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Test and debug circuit cards. Create drawings in AutoCAD, ACCEL (schematic), and Adobe Illustrator. Manage and create procedures, parts lists, and other engineering documents and spreadsheets. Basic chassis wiring.

TEACHING EXPERIENCE 2005 Instructor, Women In Engineering Connections Program, Boston, MA

Teach weekly physics review sessions, prepare physics review sheets, and tutor struggling students geared towards freshman engineering students, with the goal of increasing freshman women retention.

2005 Instructor, STEM Teach, Boston, MA Teach middle school students at a local public school an NSF engineering module “4 Schools for Women in Engineering” to teach students engineering skills using gender-inclusive approaches as part of the science curriculum as well as encourage students, especially women, to pursue engineering.

2001-2005 Tutor, Northeastern University, Boston, MA Tutor in Calculus, Physics, and Algorithms and Data Structures.

2002-2005 Tutor, Greater Boston Area, Boston, MA Tutor students from middle school through college level in various subjects, especially Calculus. Also tutor through Summit Educational Group offering in-home tutoring in math and physics as well as SAT and AP test preparation.

COURSES University of Michigan: Public Policy in Science & Technology, Machine Learning, Function Methods in System Theory, Advanced Calculus, Advanced Topics in Signal Processing, Estimation and Detection Theory, Image Processing, Medical Imaging Lab, Medical Imaging, Probability, Mathematical Methods for Signal Processing.

Northeastern University: Senior Capstone Design Project, Digital Signal Processing , Noise and Stochastic Processes Communication Systems, Networks, Computer Architecture, VLSI, Discrete Systems, Electromagnetic Fields and Waves, Electronics, Digital Logic, Circuits 1&2, Engineering Design (AutoCad); Optimization Methods (C++), Engineering Programming Models and Structures (C++), Data Structures & Algorithms (Java), Problem Solving with Applications (C, Excel, Matlab); Calc 1,2,3 & 4, Differential Equations, Discrete Math, Linear Algebra; Physics 1,2,3 & 4; Technical Writing.

PROFESSIONAL AFFILIATIONS IEEE Society of Women in Engineering Tau Beta Pi – The Engineering Honor Society

SERVICE 2008-2009 National Science Foundation Fellowship Panel, University of Michigan, Ann Arbor, MI 2002-2003 Pediatrics Volunteer, Massachusetts General Hospital, Boston, MA 2001-2002 Webmaster, Society of Women in Engineering, Northeastern University, Boston, MA

PEER-REVIEWED PUBLICATIONS 1. A K Funai, J A Fessler, W Grissom, D C Noll. Regularized B1 mapping in MRI. IEEE Trans. Med. Imag.

Submitted as TMI-2009-0270 2. A K Funai, J A Fessler, D T B Yeo, V T Olafsson, D C Noll. Regularized field map estimation in MRI.

IEEE Trans. Med. Imag., 27(10):1484-94, Oct. 2008.

CONFERENCE PUBLICATIONS 1. A K Funai, J A Fessler. Cramer Rao bound analysis of joint B1/T1 mapping methods in MRI. Proc. IEEE

Intl. Symp. Biomed. Imag., 2010. Poster presentation.

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2. A K Funai, J A Fessler, D C Noll. Estimating K transmit B1+ maps from K+1 scans for parallel transmit MRI. Proc. Intl. Soc. Mag. Res. Med., p. 2609, 2009. Poster presentation.

3. R. Reisberg, A. Funai, and B. Maheswaran. "Supplemental Freshman Physics/chemistry: Programs to Support Women in Engineering." ASEE Annual Conference and Exposition, Conference Proceedings, (2009). Oral Presentation.

4. A K Funai, J A Fessler, W Grissom, D C Noll. Regularized B1+ map estimation with slice selection effects. Proc. Intl. Soc. Mag. Res. Med., p. 3145, 2008. Oral (e-poster) presentation.

5. A Funai, J A Fessler, W Grissom, D C Noll. Regularized B1+ map estimation in MRI. Proc. IEEE Intl. Symp. Biomed. Imag., pp. 616-9, 2007. Oral presentation.

6. R. Reisberg, A. Funai, A. Interrante, S. Wadia-Fascetti, B. Maheswaran. (2006) “Connections Physics Review (CPR) Program.” ASEE Annual Conference and Exposition, Conference Proceedings, (2006). Oral Presentation.

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Zhen Zhu, Ph.D.Phone: (740)2740337

Email: zhuz@ohiou.eduResearch Interests Embedded systems, software radio and programmable hardware Unmanned systems Robotic vision and laser Sensor integration GPS and CDMA signal processing Artificial intelligenceExperiences

Dec. 2010 - present Senior Research Engineer & Principal Investigator, Northrop Grumman Electronic Systems

Acquired and lead several multi-million dollar research projects Received the 2013 "Distinguished Engineering Project Achievement

Award" from the Engineer's CouncilOct. 2006 - present Adjunct Assistant Professor, School of EECS, Ohio University

Mentored undergraduate, masters and PhD students Courses taught:

Introduction to Electrical Engineering,Microcontrollers, Microprocessors, Intermediate Electronics Lab,Electrical Navigation, Integrated Navigation, GPS Receiver Design

Oct. 2006 - Dec. 2010 Senior Research Engineer, Avionics Engineering Center, Research on aircraft navigation and landing systems

Sponsored Research At Northrop Grumman:1. PI, Collaborative Robust Integrated Sensor Positioning (CRISP), 2010 to present

Sponsored by Air Force Research Lab (AFRL), vision aided navigation and a collaborative solution between heterogeneous airborne platforms

2. PI, All Source Positioning and Navigation (ASPN), 2011 to presentSponsored by Defense Advanced Research Projects Agency (DARPA), design of a plug and play navigationarchitecture

3. PI, Northrop Grumman internal research projects on vision-aided navigation for ground and airborne systems, 2010 to present

4. Navigation Algorithm leader, Autonomous Control of UAS Ground Operations in the Terminal Area (ACUGOTA), 2011 to presentSponsored by AFRL, autonomous operation of UAVs at civilian airports

5. Algorithm leader, Micro Airborne GPS, IMU, and imagery Combination (MAGIC), 2012 to presentSponsored by AFRL, precise navigation and geo registration for UAVs in GPS and GPS-denied environments

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At Ohio University:1. Local and Wide Area Augmentation Systems (LAAS/WAAS), 2000 to 2010

Sponsored by Federal Aviation Administration (FAA), GPS-based aircraft landing system2. Sferics-Based Underground Geopositioning, 2010

Sponsored by DARPA3. Tightly-Integrated LADAR/INS Algorithm Development to Support Urban Operations, 2008 to 2010

Sponsored by Air Force Office of Scientific Research (AFOSR)4. Integrated Intelligent Flight Deck, 2007 to 2010

Sponsored by NASA, runway obstacle detection5. PI, GPS/WAAS receiver design, 2004 to 2008

Sponsored by FreeFlight Systems, design and certification of avionics including GPS receiver

EducationAug. 2006 Ph. D. of Electrical Engineering, Ohio University Jun. 2002 M. S. of Electrical Engineering, Ohio University

Professional Memberships and Services

1. IEEE: Senior Member; Student Conference Chair 2009-2010, IEEE Columbus Section2. Institute of Navigation (ION): Session Chair, ION GNSS meeting 2007, ITM 2011, GNSS 2012; Parkinson

Award Committee3. GPS Solutions Journal: Editorial Board Member , 2009 to present4. SPIE: Instructor, 2009 to present5. Sigma Xi (The Scientific Research Society:) OU chapter Treasurer, 2007 to 2010,6. Reviewer, IEEE Trans. AESS. IEEE Trans. CST., Navigation, Signal Processing, Journal of Information Sciences,

Applied Soft Computing Journal

Peer-Reviewed Journal Publications1. "Carrier Phase Multipath Error Characterization and Reduction in Single Aircraft Relative Positioning," J.

Dickman, Z. Zhu and C. Bartone, GPS Solution, April 2009.2. "Remote-Controlled, Continuously Operating GPS Anomalous Event Monitor" S. Gunawardena, Z. Zhu, M.

Uijt de Haag and F. van Graas, Navigation, Vol. 56 No. 2, 20093. “Earth-Surface Multipath Detection and Error Modeling for Aircraft GPS Receivers,” Z. Zhu and F. van Graas,

accepted by Navigation, Vol. 56 No. 1, 20094. “Optimized Approximation Algorithm in Neural Network without Overfitting,” Y. Liu, J. Starzyk and Z. Zhu,

IEEE Trans. On Neural Networks, June 2008. 5. “GPS Signal Acquisition Using the repeatability of Successive Code Phase Measurements,” Z. Zhu and F. van

Graas, (online first) in GPS Solutions, Springer-Verlag, 2007. 6. “Self-Organizing Learning Array and its Application to Economic and Financial Problems,” Z. Zhu, H. He, J. A.

Starzyk and C. Tseng, Journal of Information Sciences, Vol. 177, Issue 5, pp. 1180-1192, March 2007. 7. “Associative Learning in Hierarchical Self Organizing Learning Arrays,” J. A. Starzyk, Z. Zhu and Y. Li, IEEE

Trans. on Neural Networks, vol.17, no. 6, pp.1460-1470, November 2006. 8. “Self-Organizing Learning Array,” J. Starzyk, Z. Zhu and T. Liu, IEEE Trans. on Neural Networks, vol. 16, no. 2,

pp. 355-363, March 2005. 9. ”Fast Direct GPS P-code Acquisition,” J. Pang, F. van Graas, J. Starzyk and Z. Zhu, GPS solutions, vol. 7 no. 3,

pp. 168-175, December 2003.

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Under preparation:1. "3D LADAR Navigation with Integrity"2. "Attitude of In-door Ground Vehicle from 2-D LADAR Scans"3. "Tight Optical Integration, the Algorithm and Experimental Results”4. "C/A Code Cross-Correlation and Its Effect on GPS Receivers"

Other Publications

1. "Scalable Architecture for Plug-and-Play Navigation," H. Park, Z. Zhu, P. Dimonte, and K. Kirwood, Presented at the JSDE/ION Joint Navigation Conference, June 2012.

2. "Architecture for Asymmetric Collaborative Navigation", Z. Zhu , S. Roumeliotis, J. Hesch, H. Park, D. Venable , Proc. IEEE/ION PLANS Conf., Myrtle Beach, SC, 2012

3. "Tropospheric Delay Threats for the Ground Based Augmentation System," Z. Zhu, F. van Graas, Proc. ION ITM., San Diego, CA, 2010

4. “First Look-Observing the GPS L5 Test Transmission from SVN49 Using Software Radio Processing,” S. Gunawardena, Z. Zhu and M. Braasch, INSIDEGNSS, Summer Issue, 2009

5. “Integration of Forward-looking Infrared (FLIR) and Traffic Information 6. for Moving Obstacle Detection with Integrity,” Zhen Zhu, Sudha Vana, Sumit Bhattacharya, Maarten

Uijt de Haag, SPIE Defense, Security and Sensing Conf., Orlando, FL, April 2009,7. "GNSS Watch Dog: A GPS Anomalous Event Monitor," Z. Zhu, S. Gunawardena, M. Uijt de Haag F. van

Graas and M. Braasch, Cover Story of INSIDEGNSS, Fall Issue, 20088. "Triple Frequency RF Front-End for GNSS Instrumentation Receiver Applications," S. Gunawardena, Z.

Zhu, and F. van Graas, Proc. ION GNSS Conf., Fort Worth, TX, September 2008,9. "Runway Obstacle Detection Using Onboard Sensors: Modeling And Simulation Analysis," Proc. 27th

Digital Avionics Systems Conf., A. Vadlamani, M. Smearcheck, S. Bhattacharya, Z. Zhu, M. Uijt de Haag, St. Paul, MN, October 2008

10. "An Evaluation of the Tight Optical Integration (TOI) Algorithm Sensitivity to Inertial and Camera Errors," S. Bhattacharya, T. Arthur, M. Uijt de Haag, Z. Zhu and K. Scheff, Proc. IEEE/ION PLANS Conf., Monterey, CA, May 2008

11. "Demonstration of the Tight Optical Integration (TOI) Algorithm using Field Data," T. Arthur, Z. Zhu, S. Bhattacharya, K.L. Johnson and K. Scheff, Proc. IEEE/ION PLANS Conf., Monterey, CA, May 2008

12. "Performance Analysis and Integrity Aspects of Tight Optical Integration (TOI) with GPS," M. Uijt de Haag, Z. Zhu and T. Arthur, Proc. IEEE/ION PLANS Conf., Monterey, CA, May 2008

13. "An Algorithm for GPS Tight Optical Integration," S. Bhattacharya, T.Arthur, Z. Zhu, Proc. ION National Technical Meeting, San Diego, CA, January, 2008

14. “Advanced GPS Performance Monitor,” Z. Zhu, S. Gunawardena, M. Uijt de Haag and F. van Graas, Proc. ION GNSS Conf., Forth Worth, TX, September 2007.

15. “Satellite Anomaly and Interference Detection Using the GPS Anomalous Event Monitor,” Z. Zhu, S. Gunawardena, M. Uijt de Haag and F. van Graas, Proc. ION Annual Meeting, Cambridge, MA, April 2007.

16. “Optimizing Number of Hidden Neurons in Neural Networks,” Y. Liu, J. Starzyk and Z. Zhu, Proc. Artificial Intelligence and Application, Innsbruck, Austria, February 2007.

17. “Remote Controlled, Continuously Operating GPS Anomalous Event Monitor,” S. Gunawardena, M. Uijt de Haag, F. van Graas and Z. Zhu, Proc. ION GNSS Conf., Forth Worth, TX, September 2006.

18. "Associative Learning in Hierarchical Self Organizing Learning Arrays," J. A. Starzyk, Z. Zhu, and Y. Li, Proc. Int. Conf. Artificial Neural Networks, Warsaw, Poland, September 2005; also included in Lecture Notes in Computer Science 2005.

19. “Operational Considerations for C/A Code Tracking Errors Due to Cross Correlation,” Z. Zhu and F. van

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Graas, Proc. ION GNSS Conf., Long Beach, CA, September 2005. 20. “Detection of Ground Reflection Multipath for Airborne Antennas,” Z. Zhu and F. van Graas, Proc. ION

GNSS Conf., Long Beach, CA, September 2005.21. "Effects of Cross Correlation on High Performance C/A Code Tracking," Z. Zhu and F. van Graas, Proc.

ION National Technical Meeting, San Diego, CA, January 2005.22. "Self-Organizing Learning Array and Its Application to Economic and Financial Problems," J. A. Starzyk,

Zhen Zhu, H. He and Zhineng Zhu, Proc. Joint Conference on Information Systems, Cary, North Carolina, September, 2003.

23. "Software Simulation of a Self-Organizing Learning Array System," J. Starzyk and Z. Zhu, Proc. 6th IASTED Int. Conf. Artificial Intelligence & Soft Comp.(ASC 2002), Banff, Alberta, Canada, July 2002.

Public presentations:24. “When Navigation Meets Artificial Intelligence - Integration of Computer Vision with GPS,” Invited

speech by the IEEE Columbus Section, August 2008.25. "Tight Optical Integration (TOI) – The algorithm and an experiment," presented at the ION Dayton

Section Luncheon., Athens, OH, May 2008. 26. “Detection of Ground Reflection Multipath for Airborne Antennas,” presented at the ION GNSS

Meeting, Long Beach, CA, September 2005; and 27. Invited speech at the 34th Annual Meeting of the Joint University Program for Air Transportation

Research (Tri-U), July 2006.

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