eye dropper concept presentation
TRANSCRIPT
5 January, 2010
Improving Patient Compliance
Blueworks – Ophthalmologic Decision Support System
• Clinical compliance is one of the critical issues in healthcare.
• In ophthalmology, this is even a bigger issue due to the inherentdifficulty of self-administrating eye-drops.
• Even when someone tries to correctly apply it, he may fail
• In chronical diseases such as glaucoma, even if diagnosis andmedication are correctly defined, patients may go irreversible blind dueto poor compliance
• Clinical trial pose the biggest challenge, due to intentional non-compliance
5 January, 2010
Compliance Assessment
Blueworks – Ophthalmologic Decision Support System
Current Solutions:
• Weight drops flasks between visits
• Ask patients to keep compliance diary
• In clinical trials, dislocate volunteers to study center every day tohave someone apply them the eye-drops
• In clinical trials, rent an hotel or private clinic• Accommodate in there all volunteers• Accommodate physicians, nurses and researchers.
• Use electronical devices to get data regarding compliance
5 January, 2010
Electronical Devices
Blueworks – Ophthalmologic Decision Support System
• Existing devices only address drop application attempts, and not itsactual success.
•Typically, they store data regarding:• Date• Time• Flask squeeze / Drop leaving flask
• As mentioned, the big question in ophthalmology compliance is:
As the drop reached the eye ?
Is that eye the correct one ?
5 January, 2010
Proposed Solution
Blueworks – Compliance Validation System
- Under development *
Success
• Video-recording of each drop application
• Device inclination sensors assess optimal angle of usage
• Sound cues guide user to optimal angle of drop
• Drop-use and recording synchronization mechanisms*
This device has a Patent Pending
5 January, 2010
Proposed Solution
Blueworks – Compliance Validation System
Failure
• Local data upload to study center via Bluetooth or USB
• Remote data upload to study-center via UMTS data-transmission *
• Drop-application success evaluation trough image analysis*
- Under development *This device has a Patent Pending
5 January, 2010
Blueworks – Compliance Validation System
• Subject identificationthrough iris pattern
• Laterality assessmentthrough iris pattern
Proposed Solution
- Under development *This device has a Patent Pending
5 January, 2010
Proposed Solution
Blueworks – Compliance Validation System
• Small-sized autonomous device
• Portable Device able to contain adrop dispenser
• Schedule alarms
• Light and sound alarms
• Remotely programmable therapeutical schedule*
Current Prototype
- Under development *This device has a Patent Pending
5 January, 2010
System Workflow
Blueworks – Ophthalmologic Decision Support System
1 - Innitial Contact 2 – Patient takes EyeDropper home 3 – Patient applies
drops as usual
4 – Patient Returns with EyeDropper
5 – Researcher plugs device to PC
6 – Data is downloaded and analysed
7 – Researcher reviews results
5 January, 2010
Alternative Workflow
Blueworks – Ophthalmologic Decision Support System
1 - Innitial Contact 2 – Patient takes EyeDropper home
3 – Patient applies drops as usual
5 – Data is received and analyzed
6 – Researcher reviews results
4 – Data is sent in real-time by GSM/UMTS
5 January, 2010
Alternative Workflow v2
Blueworks – Ophthalmologic Decision Support System
1 - Innitial Contact 2 – Patient takes EyeDropper home
3 – Patient applies drops as usual
5 – Data is downloaded 7 – Researcher reviews results
6 – Researcher analyses gathered
data
4 – Data is sent in real-time by GSM/UMTS
5 January, 2010
Researcher Software
Blueworks – Ophthalmologic Decision Support System
Define Therapy Schedule
Register / Import Patient Data Gather an Iris Sample
Step 1
Innitial
Contact
5 January, 2010
Researcher Software
Blueworks – Ophthalmologic Decision Support System
Manually define instillation success
View Gathered Videos
Step 2
Analyze
Gathered
Data
Use Algorithms
5 January, 2010
Researcher Software
Blueworks – Ophthalmologic Decision Support System
Statistics
Monthly Schedule Graphic Representation
Step 3
Review
Compliance
Results
Detailed event List
