e116 Abstracts / Journal of the American Society of Hypertension 8(4S) (2014) e115–e118

P-201

Effect of an exercise program on blood pressure, body mass index

and abdominal circumference in elderly hypertensive patients

Leandra G. Lima, Jose Maria, Thiago Bonardi, Giulliard O. Campos,

Rodrigo F. Bertani, Luria M.L. Scher, J�ulio C. Moriguti, Eduardo Ferriolli,

Nereida K.C. Lima. School of Medicine of Ribeirao Preto–University ofS~ao Paulo -FMRP- Brazil, Ribeir~ao Preto, Brazil

The study was approved by the Ethic Committee of the School of Medi-

cine of Ribeirao Preto-University of S~ao Paulo - Brazil.

Objectives: To investigate and compare the effects of ten weeks of isolated

aerobic and aerobic exercise associated with resistance exercise in blood

pressure (BP), body mass index (BMI) and abdominal circumference

(AC) older individuals with treated hypertension.

Methods: 90 elderly volunteers aged from 65 to 75 years, on regular use of

antihypertensive drugs (diuretics, ACE inhibitors, angiotensin receptor

blockers or calcium channel blockers (diidropiridinic)) were selected.

We excluded those with diabetes, BP greater than 160/100 mmHg, use

of medications beta-blockers, obese grade II and III. Of the 90 seniors,

44 were able to perform the study protocols. Subjects were randomized

into 3 groups : G1 (aerobic training, n ¼ 15 ), G2 ( aerobic training

with anaerobic, n ¼ 15 ) and G3 (control, n ¼ 14 ). The aerobic sessions

were held three times per week at intensity between 50% to 80% of

maximum heart rate obtained by the maximum exercise test. The

maximum load work was calculated by one-repetition maximum (1RM)

and they exercised at 50 to 60% of 1RM. The ambulatory blood pressure

monitoring (ABPM - Space Labs Medical , 90207 ) was installed in the left

arm, lasting for 24 hours, in before and after 10 weeks. The measurements

of weight, height and abdominal circumference before and after training

were also obtained. Statistics: We used the linear regression model with

mixed effects and the Pearson correlation test.

Results: Mean age was 68.5�5.1 years, with no diferences between

groups (p ¼ 0:44), with a predominance of women (84 %) in the three

groups (p ¼ 0:32 ). After 10 weeks of training, systolic BP (SBP) was

reduced of 4.2 mmHg and 7.7 mmHg for G1 and G2, respectively. G3

had an increase of 5.7 mmHg during the 10 weeks. . Basal diastolic BP

(DBP) was 75.4 mmHg in G1 , 75.8 mmHg in G2 and 72.8 mmHg in

G3 , modifying these values to 72 mmHg, 72 mmHg and 73.7 mmHg,

respectively. BMI values were reduced in G1 (p¼0.01) , G2 (p¼0.01)

and increased in G3 (p¼0.01). Similarly, measures the abdominal circum-

ference decreased in G1 (p <0.01) and G2 (p < 0.01), while the values of

G3 tended to increase at the end of observation (p¼0.07). BMI values were

correlated with: SBP 24 (p < 0.01, rho 0.6); waking SBP (p<0.001, rho

0.7) ;sleep SBP (p<0.001, rho 0.6 ); DBP 24 (p¼0.001; rho 0.47), DBP

wake / sleep (p<0.001; 0:56 rho / p¼0.001, rho 0:45 ) and fat mass

(p<.001, rho 0.74) .

Conclusion: Ten weeks of isolated aerobic training and combined aerobic

and resistance training were equally effective in reducing BP, in decreased

abdominal circumference and body mass index. The weight loss achieved

with the training may have influenced the drop in blood pressure.

Keywords: aerobic and resistance exercises; blood pressure; body compo-

sition; elderly

P-202

Effects of a clinic-initiated behavioral nutrition intervention

emphasizing the dash diet on blood pressure control in adolescents

with elevated blood pressure

Sarah C. Couch,3 Brian E. Saelens,2 Kelli Hinn,3 Katie B. Dart,1

Phil Khoury,3 Mark Mitsnefes,3 Stephen R. Daniels,4 Elaine M. Urbina.3

1Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United

States; 2University of Washington, Seattle, WA, United States; 3University

of Cincinnati, Cincinnati, OH, United States; 4University of Colorado,

Denver, CO, United States

Change in systolic BP (SBP), diastolic BP (DBP), and diet quality were

compared among adolescents with elevated BP who participated in either

a 6-month clinic-initiated behavioral nutrition intervention emphasizing

the DASH diet or usual hospital-based nutrition care for BP management.

Adolescents with pre-hypertension or stage 1 hypertension (n¼159), newly

enrolled in a hospital-based hypertension clinic, were randomized to the

DASH intervention (DASH, n¼81) or usual nutrition care (UC, n¼78).

Exclusion criteria: use of BP altering medications, receipt of prior formal-

ized diet therapy, presence of target organ damage, diagnosed diabetes or

an eating disorder. The DASH intervention included 2 counseling sessions

with a dietitian on the DASH diet, 6 mailings and 15 telephone calls on

behavioral strategies to promote dietary change. UC included 2 sessions

with a dietitian on dietary guidelines consistent with the Fourth Pediatric

Report of the National High Blood Pressure Education Program. Adoles-

cents in both groups were prescribed calorie levels for weight mainte-

nance. Physical activity was encouraged, but was not a target for

change. Weight, height, 3-day dietary intake, 7-day physical activity (con-

verted to MET minutes), SBP and DBP were assessed at pre-treatment

(baseline) and after the 6 month intervention. General linear regression

models were used to compare BP and diet change (post-treatment - base-

line) between groups; models adjusted for demographics (age, gender,

race, and income), change in BMI z-score, change in daily MET minutes,

and baseline BP and nutrient level as appropriate. Based on intention-to-

treat analyses, changes in SBP and SBP z-score were greater among

DASH participants vs. UC (means + SD, SBP: -3.4 + 6.5 vs. -0.6 + 7.1

mm Hg, p¼ 0.02; SBP z-score: -0.4 + 0.7 vs. -0.2+ 0.7, p¼0.03); change

in DBP and DBP z-score did not differ between groups. Changes in daily

servings of fruit (2.0 + 2.3 vs. -0.4 + 1.7, p<0.0001), vegetables (0.9 + 1.5

vs. 0.3 + 1.5, p¼0.04), low fat dairy (0.9 + 1.2 vs. -0.2 + 0.7, p<0.0001),

total fat (-5.5 + 7.8 vs. 0.1 + 1.4 % kcal; p<0.001) and sodium (-316 +

1052 vs. 197 + 1287 mgs; p¼0.01) were greater in DASH vs. UC. Findings

suggest that a 6-month telephone and mail-based behavioral nutrition inter-

vention initiated in tertiary care emphasizing the DASH diet can improve

BP and diet quality in adolescents over usual hospital-based nutrition care

for BP management. Supported by NIH Grant R01HL088567

Keywords: nutrition intervention; adolescents; dietary pattern;

hypertension

P-203

Eligibility for renal denervation: experience from 11 European

expert centers

Alexandre Persu,1 Yu Jin,12 Marie Baelen,1 Michiel L. Bots,10

Bernhard Schmidt,6 M. Blicher,5 Francesca Severino,1

Gr�egoire Wuerzner,8 Alison Taylor,11 Antoinette Pech�ere-Bertschi,4

Fadi Jokhaji,2 Fadl Elmula Fadl-Elmula,13 Jan Rosa,3 Danuta Czarnecka,7

Georg Ehret,4 Thomas Kahan,2 Jean Renkin,1 Jiri Widimsk�y,3

Lotte Jacobs,12 Wilko Spiering,10 Michel Burnier,8 Patrick B. Mark,11

Jan Menne,6 M. Olsen,5 Peter Blankestijn,10 Sverre Kjeldsen,13

Jan A. Staessen.12,.9,

earch on Renal Denervation (ENCOReD) Consortium on Behalf of theEuropean Network COordinating Res 1Cliniques Universitaires Saint-Luc

(UCL), Brussels, Belgium; 2Danderyd Hospital, Stockholm, Sweden;3General Faculty Hospital, Prague, Czech Republic; 4Geneva University

Hospital, Geneva, Switzerland; 5Glostrup University Hospital, Glostrup,Denmark; 6Hannover Medical School, Hannover, Germany; 7Jagiellonian

University Medical College, Krakow, Poland; 8Lausanne University

Hospital, Lausanne, Switzerland; 9Maastricht University, Maastricht,Netherlands; 10University Medical Center, Utrecht, Netherlands;11University of Glasgow, Glasgow, United Kingdom; 12University of

Leuven, Leuven, Belgium; 13University of Oslo, Oslo, Norway

Objective: To investigate the proportion of patients eligible for renal

denervation (RDN) and the reasons of non-eligibility in 11 expert centres