effective strategies for blood pressure control
TRANSCRIPT
Effective strategies for blood pressure controlVerna L. Lamar Welch, PhD, MPHa,b,*,
Martha N. Hill, RN, PhD, FAANc
aFormerly, Division of Applied Public Health Training, Epidemiology Program Office, assigned
to the Cardiovascular Health Branch, Division of Adult and Community Health, National Center
for Chronic Disease Prevention and Health Promotion,
Centers for Disease Control and Prevention, 4770 Buford Highway, Atlanta, GA, USAbCenter on Health Outcomes and Quality, Emory University, School of Public Health, 1518 Clifton Road, NE,
Room 670, Atlanta, GA 30322, USAcCenter for Nursing Research, Johns Hopkins University School of Nursing, 525 N. Wolfe Street,
Baltimore, MD 21205-2110, USA
Hypertension is the leading preventable cause
of premature morbidity and mortality from cor-
onary heart disease, stroke, heart failure, and kid-
ney failure. Although substantial progress has
been made in developing and distributing both
antihypertensive medications and guidelines for
hypertension treatment, rates of blood pressure
control remain dismal. Of the estimated 50 million
Americans with hypertension, less than one fourth
have their blood pressure under control. One-year
costs of failing to control hypertension were
recently estimated at $964 million for the total
US hypertensive population and $467 million for
those being treated [1]. This article describes effec-
tive strategies for blood pressure control at
national, state, and community levels.
Background
One in four US adults, as many as 50 million
Americans, has hypertension [2]. From the second
phase (1991–1994) of the National Health and
Nutrition Examination Survey, researchers esti-
mated that of persons with hypertension, 31.6%
were unaware of their condition, 14.8% were not
on any therapy (including special diet or medica-
tions), 26.2% were on inadequate therapy, and
27.4% were on adequate therapy and had their
blood pressure under control. Hypertension is a
costly disease that is associated with an increased
risk for most forms of cardiovascular disease,
especially in the coronary, cerebrovascular, renal,
and peripheral vascular beds [2–6].
The Healthy People 2010—National Health
Promotion and Disease Prevention Objectives in-
cludes as one objective an increase to 50% by
the year 2010 in the proportion of adults with high
blood pressure who have it under control [7]. This
is a major challenge but one that seems attainable
with community-based and team approaches.
Effective strategies for blood pressure control are
summarized in Table 1.
Public health approaches
in hypertension prevention
Research has shown that reducing sodium con-
sumption, losing weight, engaging in regular physi-
cal activity, and taking medications can lower
elevated blood pressure. To translate research into
practice, in 1972 the National Heart, Lung, and
Blood Institute (NHLBI) undertook amajor initia-
tive, the National High Blood Pressure Education
Program (NHBPEP), which has used mechanisms
ranging from setting guidelines for optimal blood
pressure levels, to national educational campaigns,
to community-based demonstration projects.
Cardiol Clin 20 (2002) 321–333
* Corresponding author. Center on Health Out-
comes and Quality, Emory University, School of Public
Health, 1518 Clifton Road, NE Rm. 670, Atlanta, GA
30322.
E-mail address: [email protected](V.L.L.Welch).
0733-8651/02/$ - see front matter � 2002, Elsevier Science (USA). All rights reserved.
PII: S 0 7 3 3 - 8 6 5 1 ( 0 1 ) 0 0 0 0 7 - 8
NHBPEP
The NHBPEP is a cooperative effort of profes-
sional and volunteer health agencies, the federal
government, state health departments, and com-
munity groups. NHBPEP’s goal is to reduce
death and disability related to uncontrolled
hypertension through programs of professional,
patient, and public education. The program offers
resources in information collection and dissemina-
tion; public, patient and professional education;
community program development, evaluation,
and data analysis; and technology transfer and
electronic distribution [8]. There is no empiric eval-
uation data for the NHBPEP, but the vast inc-
rease in public knowledge signals its effectiveness.
In 1972, less than one fourth of the American
population was aware of the relationships between
hypertension and both stroke and heart disease
and the benefits of treating and controlling hyper-
tension. Today, more than three fourths of Amer-
icansareawareof these relationships.Furthermore,
Americans know the importance of having their
blood pressure measured, and three fourths have
it measured every 6 months [9].
NHLBI community-based demonstration projects
In the 1970s, responding to new evidence on
the effectiveness of hypertension control, the
NHLBI began to sponsor innovative community-
based demonstration projects. The overarching
goal of four NHLBI sponsored projects, begun
in 1972, 1978, and 1980 (two projects), respec-
tively, was to develop and evaluate educational
strategies leading to a decreased population risk
of cardiovascular disease. The studies were carried
out independently but concurrently and in tech-
nical cooperation with each other.
Table 1
Effective strategies for blood pressure control
Level Setting/program Strategy
National National High Blood Pressure
Education Program
Provide resources in information collection and
dissemination; public, patient, and professional
education; community program development;
evaluation and data analysis; and technology
transfers and electronic distribution
Community-based
demonstration projects
See Table 2
State-run programs Preventive Health and Health
Services Block Grant
Provide funds to 61 grantees for preventive health
services to reduce illness and premature death and
improve quality of life
Centers for Disease Control and
Prevention—Cardiovascular
Health Branch
Provide funds, technical support, surveillance data,
epidemiologic analyses, and public health
recommendations to states and territories
Community health
partnerships
Work site Onsite screening, onsite antihypertensive treatment
during work hours, referrals to community
resources, and health education
Faith-based organizations Health education, onsite screening, referrals; use
existing volunteer pool and lay health workers.
Barbershops/beauty
salons/fire stations
Onsite screening, health education, referrals, regular
clientele, and convenient locations
Pharmacies Onsite screening, health education, referrals, follow-up
calls for encouragement and to monitor compliance,
home blood pressure monitoring, and management
of drug reactions
Community outreach Comprehensive approach with social, psychological,
behavioral, economic, and biomedical components
Clinical care Nurse-run clinics Comprehensive approach incorporating information
regarding the patient’s background, social
environment, lifestyle, health history, and other
relevant factors to develop a health plan; referrals,
follow-up, and maintenance therapy
322 V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
The Stanford Three-Community Study
(1972–1975)
The Stanford Three-Community Study was a
demonstration project conducted in northern Cali-
fornia in three nonrandomized communities: two
treatment and one control. Designed to develop
and evaluatemethods for achieving positive behav-
ioral change that would be both cost-effective
and applicable to large populations, the study
involved comprehensive media campaigns to edu-
cate community residents about cardiovascular dis-
ease risk factors, including hypertension. Special
programs were developed for Spanish-language
media, and school-based programs were developed
to reach students, parents, teachers, and adminis-
trators. In the two treatment communities, health
promotionmaterialswere disseminated via a 2-year
mass media campaign; in one of these communities
individual counseling was provided to a randomly
selected subset of residents at high risk of develop-
ing coronary heart disease.
Residents of each community were interviewed
and examined before, during, and after the project
to assess their knowledge of and risk factors for
cardiovascular diseases. Results showed a signifi-
cant reduction in overall cardiovascular risk in
both treatment communities, when compared with
the control community. Specifically, changes in sys-
tolic blood pressure were significant for the inter-
vention communities, ranging from 6.6 mm Hg to
8.9 mm Hg. Results for diastolic blood pressure
were mixed: the media-only community expe-
rienced a 2.5 mm Hg increase; in the second treat-
ment community, a 6.2 mm Hg decrease in
diastolic blood pressure was observed among the
high-risk subset and a 3.9 mm Hg decrease among
the remainder of the community. Diastolic blood
pressure decreased by 5.4 mm Hg in the control
community, resulting in no significant difference
between the treatment and control communities
on that measure [10–13].
The Stanford Five-City Project (1978–1998)
The Three-Community Study generated the
Stanford Five-City Project, which involved five
cities: two treatment and three control. A 6-year
educational intervention targeting multiple risk
factors was delivered through television, radio,
newspaper, other print materials, direct educa-
tion, and community events. Community groups
and organizations participated by conducting
activities such as workshops, conferences, and
other community forums. Health professionals
from various intermediary agencies were trained
to provide educational information on risk factors
and behavioral change [14–17].
To evaluate the effect of the intervention on
cardiovascular disease risk factors, four indepen-
dent cross-sectional surveys and four repeated
surveys of a cohort were conducted in the treat-
ment cities and two of the three control cities.
After 5.3 years of intervention, the treatment cities
observed a decline of 7.4 and 5.5 mm Hg for sys-
tolic and 5.0 and 3.7 mm Hg for diastolic blood
pressures, respectively, in the cohort and indepen-
dent surveys. The overall difference in change over
time between the treatment and control cities ran-
ged from )1.1 to )3.8 mm Hg [14].
The Minnesota Heart Health Program
(1980–1993)
The Minnesota Heart Program selected three
pairs of nonrandomized communities, with one of
each pair assigned to educational intervention
and the other to comparison status. The commu-
nities were matched for size, type, and distance
from the Minneapolis–St. Paul metropolitan area.
Means of education interventions consisted of
direct education, mass media campaigns, and com-
munity organization, the last of which was used to
involve community groups and organizations in
promoting the reduction of risk factors for cardio-
vascular disease. Constituents of the community
involved in disseminating information included
health care professionals, schools, work sites,
churches, organizations, city task forces, mass
media, grocery stores, and restaurants [18–21].
Cross-sectional surveys, a longitudinal survey,
and surveillance of morbidity and mortality were
used to evaluate the program. For the comparison
communities, the cross-sectional survey showed a
declining trend in blood pressure (annual change
of )0.4 mm Hg for systolic and )0.2 mm Hg for
diastolic), whereas the longitudinal analysis indi-
cated a flat or slightly rising trend, which is
expected with an aging cohort. In the education
communities, after 3 years the cross-sectional analy-
sis showed that both systolic and diastolic blood
pressure declined modestly (systolic from 121.7 to
118.2 mm Hg, diastolic from 76.2 to 71.6 mm Hg);
the cohort survey found after 4 years that the
systolic declined from 122.3 to 120.4 mm Hg and
the diastolic declined from 76.2 to 75.0 mm Hg.
At 6 years, the cross-sectional analysis showed a
decline in systolic pressure from 121.7 to 118.6
mm Hg and in diastolic pressure from 76.2 to
73.3 mm Hg, but none of these findings on blood
pressure was statistically significant [18].
323V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
The Pawtucket Heart Health Program
(1980–1997)
The Pawtucket Heart Health Program used a
longitudinal design to follow a treatment (Paw-
tucket, RI) and a control (New Bedford, MA)
community, which were similar sociodemographi-
cally. Pawtucket received a 7-year intervention
consisting of community-wide educational strat-
egies that emphasized public awareness campaigns,
behavioral change, and community activation to
promote involvement and environmental change.
More than 500 community organizations, includ-
ing schools, faith-based organizations, social orga-
nizations, work sites, and city government, were
involved [22–24].
An evaluation unit conducted random house-
hold surveys, designed and implemented a complex
process evaluation system, and monitored relevant
changes in Pawtucket and New Bedford. The over-
all outcome evaluationwas based on surveys froma
cross-sectional random sample of 1200 persons
aged 18 to 65 years in Pawtucket and an equal num-
ber from New Bedford. The initial survey was con-
ducted in 1981 and repeated every 2 years through
1993. No statistically significant effect on blood
pressure was found for the program.
The community-based intervention projects
highlighted above had several common interven-
tion strategies, including direct education of the
general public and health professionals through
media and personal contact and community
mobilization to foster institutional and environ-
mental support (Table 2). Variations were ob-
served in effectiveness, but each study successfully
developed and implemented its community-based
intervention. Taken together, the estimated net in-
tervention effect for systolic blood pressure was an
annual reduction of approximately 0.6 mm Hg in
the treatment cities. Overall, no significant differ-
ences were observed in diastolic blood pressure
between treatment and control cities [25].
State-run programs in hypetension detection,
treatment, and control
In the early 1980s, broader initiatives emerged
at the national, state, and local levels to address
the burden of cardiovascular disease and the need
for risk factor intervention. Although these initia-
tives had a goal similar to the community inter-
vention trials, a different approach was taken,
not as scientifically rigorous and more focused on
community involvement. Broad coalitions invol-
ving groups such as patients, the medical commu-
nity, family and children services, community
organizations, pharmaceutical companies, and
government adopted initiatives. Programs to iden-
tify persons with hypertension, refer them to care,
and improve blood pressure control rates incorpo-
rated the principles of health promotion as the
first step in disease prevention. Funding came
from federal, state, and local government as well
as private sources. State-run programs in hyper-
tension detection, treatment, and control were
instrumental to the success of these initiatives.
The next section of this article reviews two fund-
ing mechanisms for the state-run programs.
The Preventive Health
and Health Services Block Grant
In the 1970s, earmarked funds were designated
to states for hypertension screening programs. All
the states participated and eventually developed
hypertension detection and control programs. In
1981, Congress combined various areas of health
funding, including the hypertension program, into
the Preventive Health and Health Services Block
Grant. This grant provides funds to 61 grantees to
reduce illness and premature death and improve
the quality of life [26]. Grantees are the 50 states,
the District of Columbia, eight territories, and
two tribes. The goal is to provide states with the
flexibility and autonomy to tailor prevention and
health promotion programs to address their prior-
ity health needs. In 1992, changes were made that
require states to (1) submit a state health plan
that specifies health outcome objectives, describes
health problems, and identifies target populations,
and (2) account for their funding by evaluating and
reporting on program activities and health indica-
tors [26].
Chronic disease prevention and health promo-
tion is one of the seven major program areas
funded; funds secured under this umbrella can
be used for hypertension detection, treatment,
and control. For fiscal year 2000, more than $26
million was given to 47 of the 61 grantees to
address health issues related to coronary heart dis-
ease, and stroke, and end-stage renal disease.
Cardiovascular Health Branch of
the Centers for Disease Control and Prevention
The mission of the Centers for Disease Control
and Prevention’s Cardiovascular Health Branch
(CHB), which is within the agency’s Division
of Adult and Community Health, is to promote
cardiovascular health and prevent disability and
324 V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
Table
2
Community-baseddem
onstrationprojectsoftheNationalHeart,Lung,andBloodInstitute
Study
Interventionactivities
Setting(treatm
ent:control)
andpopulationsize
Years
ofintervention
Changes
inbloodpressure
(mm
Hg)
Stanford
Three-Community
Study
TV,radio,new
spaper,
printedmaterials,
directeducation
3towns(2:1);n¼45,000
1972–75
SBP:)6.6
to)8.9
DBP(m
edia
only
group):+2.5
Stanford
Five-CityProject
TV,radio,new
spaper,
printedmaterial,
directeducation,community
activities
5cities
(2:3);n¼350,000
1980–86
SBP(city1):)7.4
SBP(city2):)5.5
DBP(city1):)5.0
DBP(city2):)3.7
Minnesota
Heart
Health
Program
Mass
media,community
organization,directeducation
2towns,
2cities,2suburbs(1:1);
n¼412,371
1981–88
SBP:)0.4
DBP:)0.2
Pawtucket
Heart
Health
Program
Communityorganization,printed
materials,environmental
programs,community
volunteers
2cities
(1:1);n¼169,682
1984–91
SBP(treatm
ent):)1.81
SBP(control):)0.42
DBP(treatm
ent):0.28
DBP(control):1.12
Abbreviations:DBP,diastolicbloodpressure;SBP,systolicbloodpressure
325V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
premature death. Prevention of hypertension is
a major initiative. To accomplish this goal, the
CHB provides funding, technical support, state-
specific surveillance reports, epidemiologic anal-
yses, and public health recommendations to states
and territories. In fiscal year 2001, 25 states received
more than $15 million from the branch to develop
state cardiovascular health programs. The CHB
also funds two projects designed to reduce the
high prevalence of hypertension in older, African-
American women in two low-income communities:
Project Joy, a church-based project in urban Balti-
more,MD, and TheUniontown Project, a commu-
nity-based project in rural Alabama. Both projects
are evaluating the efficacy of a lay leader model
in delivering a 12-month cardiovascular health
program to the leader’s peers [27].
Community health system partnerships
Community health system partnerships offer
approaches that complement hypertension control
programs in the primary care setting, with a wide
variety of organizations and community members
working collectively to accomplish a common
goal. Such partnerships use diverse strategies,
including health education, community develop-
ment, advocacy for policy and environmental
change, screening and early detection and treat-
ment. These strategies can provide monitoring of
hypertension control and, with appropriate coun-
seling, reinforce the achievement of hypertension
treatment and control goals.
The community-wide approach potentially
involves all persons living or working in the com-
munity, including community leaders, policy-
makers, employers, employees, business owners,
members of volunteer and civic organizations,
faith-based organizations, and families. Box 1
summarizes lessons learned from community
health system partnerships. The following are
examples of community settings in which hyperten-
sion programs have been implemented.
Work sites
Promoting health in the workplace serves as a
vehicle for employees to increase their awareness
of specific health risks, develop more positive
health attitudes, and adopt healthier lifestyles.
Box 1. Community Health System Partnerships: Lessons Learned
Work site hypertension programs are• economically feasible• easy to implement• safe, acceptable, and effective when overseen by nurses
Faith-based organizations are• present in most communities and have a history of volunteering and outreach• ideal settings for hypertension programs• important venues for health promotion and disease prevention programs, not only
among their members but nonmembers as wellBarbershops and beauty salons are
• prevalent in most communities• venues for social, political, and educational activities• ideal for screening because customers visit frequently and are a captive audience while
receiving servicesFire stations are
• attractive settings for screening because they are easily accessible• ideal for screening because they are open 24 hours a day, 7 days per week
Pharmacists are• positive influences on medication compliance when included in the health care delivery
team• valuable resources who can encourage compliance, answer questions, manage mild
drug reactions, monitor blood pressure, and provide referrals when needed
326 V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
The goal is to increase healthy behaviors among
employees and thereby improve job performance.
Hypertension is a common condition at most
work sites, with prevalence estimates ranging from
15%to25%[28].Manycompanies,whichasagroup
spend billions on health care costs, realized some
time ago the advantages of health promotion pro-
grams. Studies have shown that work site hyperten-
sion programs, which are primarily overseen by
nurses, are safe, acceptable, and effective [29,30].
Their success is due in part to the controlled envir-
onment and because these programs are economic-
ally feasible and easy to implement. Screening can
be done fairly quickly during working hours.
Employees diagnosed with hypertension can be
referred to community resources for treatment or
providedwith antihypertensive therapy at thework
site. Referring to community resources has been
found less effective in maintaining a long-term regi-
men than systematic approaches to care at thework
site [29,31,32]. Alderman [29] reported that less
than 50% of workers referred to community
resources actually visited a physician, and among
those who did, only 50% had achieved and main-
tained control of their blood pressure 2 years later.
In contrast, more than 80% of those managed at
the work site achieved and maintained control.
Similarly, a voluntary onsite screening, referral,
and follow-up hypertension program conducted
by the Massachusetts Mutual Life Insurance
Company resulted in an increase of controlled
hypertension from 36% to 82% after 1 year of
operation [33].
Work site programs that focus on hypertension
have shown potential for success in reducing
blood pressure. The programs are accessible at
little or no cost to the recipient with systematic
monitoring and ongoing patient education pro-
vided. These programs generally rely on multidis-
ciplinary teams working by a well-defined,
stepped-care protocol. Globally instituting such
programs might serve as a mechanism to improve
hypertension control. The cost of work site hyper-
tension programs may vary substantially, how-
ever. When calculating cost, employers must
consider program frequency, level of control
achieved, cost of treatment, impact on disability
costs, effect on absenteeism, cost of heart attacks
and strokes, and so forth [28]. Once established,
work site hypertension programs benefit both
the employees and the employers. For the
employee, they provide a convenient and econom-
ical means for hypertension management. For the
employer, the initial start-up cost is recovered
through a healthier and more productive work-
force [28].
Faith-based organizations
Faith-based organizations can be an ideal set-
ting for detection, treatment, and control pro-
grams. These organizations exist in virtually every
community and may serve not only as places for
worship but also as places for social, political, and
educational activities. Their leaders are often well
known and respected in the community and sought
after for advice. Generally, the organizations have
congregations with a diversity of experience (blue
collar, white collar, government, industry, etc.)
and a history of volunteering and outreach. Mem-
bers may work in a variety of settings and be
involved in other community organizations. The
collaboration between faith-based organizations
and the community further facilitates the dissemi-
nation of health programs. These traits make
faith-based organizations attractive sites for imple-
menting and sustaining health programs [34–38].
Since 1970, Hatch and colleagues have imple-
mented faith-based education programs in rural
black communities in the South, with hyperten-
sion often a major focus. Positive results from
these programs show that it is feasible to conduct
health education programs in faith-based organi-
zations [34–39]. In 1978, a consortium of health-
related organizations requested and received
funding from the NHLBI to organize churches
as hypertension control centers. Three years later,
the National Black Health Providers Task Force
on High Blood Pressure Education and Control
recommended the use of faith-based organizations
for health education [40,41].
In 1994, the American Heart Association laun-
ched a national faith-based campaign, ‘‘Search
Your Heart,’’ to reach persons in church settings
and encourage them to change their lifestyle so
as to make their bodies heart healthy. This cam-
paign, which also focused on high blood pressure
education, was revamped in 1997 to include com-
ponents addressing blood pressure screening, phy-
sical activity, nutrition, and stroke [42].
Although data on the effectiveness of faith-
based hypertension programs is not readily avail-
able, this approach has wide support [34–38], In
addition, a 1994 Gallup survey found that 60% of
Americansbelieved that religionwas important and
that 42% attended church weekly or almost weekly
[43]. Results from the Pawtucket Heart Program
support the use of faith-based organizations
327V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
for health promotion; 58% of persons attending
health education events at faith-based organiza-
tions were members of the sponsoring organiza-
tion, 24% were members of another faith-based
organization, and just 18% were not members
of any faith-based organization. These results
suggest that not only members of the sponsoring
organization but also nonmembers attend health
education events sponsored by faith-based organi-
zations [22–24]. Furthermore, although much of
the experience has been in the black community,
faith-based organizations may serve as important
venues for health promotion and disease preven-
tion programs with other minority groups, particu-
larly Hispanics [34,44–46].
Barbershops/beauty salons/fire stations
Barbershops, beauty salons, and fire stations,
as in the case with faith-based organizations, may
serve as places for social, political, and educational
activities. Two published accounts, both by Kong
[47,48], document the use of barbershops and
beauty salons as alternative settings to churches
for health programs. After researchers involved
in faith-based programs realized that men were
not using the services as frequently as were women,
they investigated the barbershops as an alternative
setting for reaching the male population. Many
men visit the barbershop on a monthly basis and,
while seated in the chair, are captive audiences
for 15 minutes of health education and could easily
get their blood pressure checked.
Beauty salons also provide opportunities to
reach unique audiences not present in other set-
tings. ‘‘Healthy Hair Starts with a Healthy Body’’
is a program started by the National Kidney Foun-
dation in Michigan in June 1999 to prevent kidney
disease. Program partners include the Michigan
Department of Community Health, Diabetes Out-
reach Networks, American Heart Association,
local health departments, hospitals and managed
care programs, and 55 stylists from 39 salons. Sty-
lists give their clients a ‘‘health chat,’’ brochures, a
risk survey, blood pressure check, and a canvas bag
of health- and beauty-related incentives [49].
Fire stations are an attractive setting for
screening because they are generally easily accessi-
ble and open 24 hours a day, 7 days per week.
Firefighters trained in measuring blood pressure
can provide free screening and counseling while
they are waiting to fight fires, affording them the
opportunity to provide an additional and needed
service while interacting with the public [47,48].
Pharmacists
With 16% to 50% of hypertensive patients dis-
continuing their medications within the first year
of treatment, compliance is a major issue. Phar-
macists, if included in the health care delivery
team, can positively influence compliance and
help achieve blood pressure control [50–53]. A
simple pairing of a physician and pharmacist
may also be effective, judging from the results of
a study by Bogden and colleagues [54]. They con-
ducted a 6-month trial in a resident teaching
clinic, in which the intervention arm consisted of
a pharmacist interacting with physicians and
patients on each visit to optimize antihypertensive
drug therapy. Patients assigned to the control arm
received the same medical care as those in the
intervention but did not receive input from a
pharmacist. At the end of the trial, almost three
times as many persons in the intervention arm
controlled their hypertension (55% versus 20%,
P\0.001) compared to the control arm. Systolic
blood pressure declined by 23 mm Hg in the inter-
vention arm and 11 mm Hg in the control arm
(P\0.01). Diastolic blood pressure dropped 14
mm Hg in the intervention arm and 3 mm Hg
among controls (P\0.001).
In another study, the intervention group mon-
itored their blood pressure at home using manual
electronic monitors and received monthly tele-
phone calls from their pharmacist to evaluate
their blood pressure response; controls received
neither intervention. After 6 months, 44% of the
intervention arm, but only 22% of controls, had
controlled their hypertension [53].
Incorporating the concept of ‘‘pharmaceutical
care,’’ in which the pharmacist assumes additional
responsibility for the patient by ensuring the
appropriate use of specific drugs to achieve the
desired outcome, is overdue in the arena of hyper-
tension control. The role of the pharmacist can and
should go beyond filling the prescription. The
pharmacist can encourage compliance, answer
questions, manage mild drug reactions, monitor
blood pressure, and provide referrals when needed.
Community outreach
Effective hypertension control programs require
a comprehensive approach that incorporates
social, psychologic, behavioral, economic, and bio-
medical components. Community outreach, which
is a proven strategy, encompasses many of these
approaches and has gone far beyond its traditional
328 V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
role of helping tomeet the needs of the underserved.
It provides the link between health professionals
and health care organizations with current or
potential patients and connects to resources in the
patients’ communities. Indeed, today community
outreach is an extension of medical and nursing
care that is used to meet marketing, public rela-
tions, and population needs as well as health pro-
motion and disease prevention objectives. Hill
and colleagues [55] cite, from the clinical perspec-
tive, three important lessons learned from including
community outreach in hypertension care and con-
trol programs:
1. Clinicians can use resources in the community
to directly enhance their care of patients, thus
improving long-term control of hypertension
and reducing associated target organ damage.
2. Community programs can provide reinforce-
ment of the clinician’s recommendations and
teaching efforts.
3. Physicians, nurse practitioners, and other
clinicians can provide community service
and leadership by accepting referrals, pro-
moting outreach programs, and acting as
consultants.
Results from clinical trials unequivocally
demonstrate that lifestyle changes combined with,
if necessary, pharmacologic intervention contri-
bute to hypertension control and reduce asso-
ciated morbidity and mortality. The challenge,
however, is translating research into practice,
which is where community outreach can play a
major role. Involving community leaders in the
design, implementation, and evaluation of out-
reach programs so that they are acceptable and
responsive to the community can be critical.
Incorporating the priorities and strategies of both
the community and health professionals reflects a
broader definition of health by recognizing its
social, cultural, and economic context [56]. To
accomplish long-term blood pressure control,
health care providers need to know and be sup-
portive of the social context of their patients’ lives.
Community outreach offers new opportunities to
explore the most cost-effective and efficient strate-
gies for hypertension control among diverse popu-
lations and those bearing a disproportionate
burden of hypertension and its sequelae [55].
Clinical care
There is no doubt that the effective control of
high blood pressure saves lives, but reaching
higher rates of control can be a daunting task.
Multidisciplinary teams involving professional
associations, government agencies, volunteer
health agencies, health care facilities, consumer
groups, community groups, community health
workers, social workers, nurses, and pharmacists
have been very successful in raising rates of high
blood pressure detection and treatment. Specia-
lized clinics with designated, well-trained staff
have achieved impressive control rates. Descri-
bed next are programs involving nurses and
pharmacists.
Nurse-managed clinics
Management of hypertensive patients, as out-
lined in many published national and interna-
tional guidelines, is complex and time consuming,
and increasing demands on physicians make them
less able to deliver such care. Since the 1950s,
however, nurses have been involved in screening
for hypertension and caring for hypertensive per-
sons and thus are ideal for delivering such care
[55,57]. Numerous studies, including national
multisite clinical trials such as the Hypertension
Detection and Follow-up Program (HDFP) and
Systolic Hypertension in the Elderly Program
(SHEP), have demonstrated the effectiveness of
nurses and nurse-managed clinics in hypertension
detection, treatment, and control [58,59].
Both the HDFP and SHEP showed that blood
pressure could be reduced effectively and that
rates of cardiovascular disease events could
be lowered by controlling hypertension [58,59].
The HDFP observed an average reduction of
5 mm Hg in diastolic blood pressure; the SHEP
showed a reduction of 4 mm Hg in diastolic blood
pressure. Less often noted is that the care in both
trials was delivered primarily by nurses, who were
responsible for screening, counseling, and medica-
tion management.
The Division of Hypertension at the Mayo
Clinic, in Rochester, MN, established a hyperten-
sion clinic that relied on a multidisciplinary team
of physicians specializing in hypertension, nurses,
dietitians, and nurse educators to achieve optimal
control of hypertension in their outpatients. A
horizontal rather than hierarchical approach was
used to manage the clinic. Nurses were responsible
for maintaining blood pressure equipment,
teaching patients, addressing compliance issues,
managing medications, reinforcing therapeutic
goals, and ensuring follow-up visits. The patients
benefited by their interaction with health care
329V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
providers in setting goals, having easy access to
medical care with no treatment delays, and
having access to home monitoring [60].
Because the nurse is often the first professional
the patient encounters within the health care
delivery system, his or her interaction with the
patient and the family influences the patient’s
behavior and attitude toward the health care sys-
tem significantly. Often the nurse incorporates
information regarding the patient’s background,
lifestyle, health history, and other relevant factors
into determining the patient’s health status and
health care plan. By understanding the social
environment, the nurse can assist the patient in
attaining and maintaining a healthy lifestyle.
Nurses can facilitate and support high blood pres-
sure control by developing a health care plan and
providing referrals, follow-up, and maintenance
of therapy after the original diagnosis of hyperten-
sion. Ultimately, having a nurse manage the
hypertensive patient instead of making a referral
to specialty care keeps patients in the primary care
setting with their provider, which can result in
more comprehensive care and an increase in com-
pliance [55,61].
Rates of control of hypertension in nurse-run
clinics are comparable to those achieved by physi-
cians [57]. Still, although the success is documented,
financial reimbursement for patient education and
counseling is usually unavailable, and in some set-
tings medical opposition to nurse practitioners
has impeded the development of nurse-managed
clinics for hypertension control. Additionally,
many people prefer to have a physician be their pri-
mary care provider and manage their health care.
Still, nurses play a critical role in the health care
delivery system and have proved beneficial in the
detection and control of high blood pressure.
Conclusion
Since the initiation of the NHBPEP, we have
seen remarkable increases in awareness, treatment,
and control of hypertension. During the past dec-
ade, however, rates of awareness and treatment
have leveled off and rates of control have declined.
Thus, health care providers and patients must not
become complacent. Providers need to give their
attention both to those with moderate hyperten-
sion and those with uncontrolled hypertension.
Hypertension that is uncontrolled usually reflects
nonadherence, undermedication, or both. Nonad-
herence to hypertension therapy is a major public
health problem, suggesting the need for innovative
intervention that takes advantage of underutilized
venues already existing in the community. Regard-
ing undermedication, additional research is needed
to explore the extent to which health care providers
are adopting the current guidelines for detecting,
treating, and managing of hypertension in daily
practice. Also warranted is an exploration of the
decision-making process used by health care provi-
ders to determine when to start drug therapy and
when to adjust the regimen to achieve optimal
blood pressure.
Technologic advances have made it possible
for patients to take a more active role at home
in their care. Telephone, fax, fax modems, electro-
nic mail, handheld and personal computers, vir-
tual physician’s offices, and the Internet are
examples of advanced technology being used suc-
cessfully to transmit data between the home and
health care settings. These technologies provide
opportunities for patient self-monitoring and
communication of information between patients
and laboratories, nurse case managers, primary
care physicians, and specialist physicians. Extend-
ing patient care into the home via these mechan-
isms has been shown to improve adherence by
allowing quick tailoring of therapy and has earned
high levels of patient and provider satisfaction
and improved outcomes [62,63].
In summary, effective strategies for blood pres-
sure control at the national, state, and community
levels are presented here. It is the intent of the
authors to provide an impetus for discussing
why the rates of hypertension awareness, treat-
ment, and control are stable in spite of the afore-
mentioned successes. Is there a need to redefine
our strategies? Clearly, increasing our prevention
efforts, improving entry into care, and promoting
adherence to treatment recommendations are
areas that demand our commitment.
References
[1] Flack JM, Doyle J, Casciano R, Arocho R,
Casciano J, Gonzales MA. The health economic
impact of failure to reach blood pressure goals. Am
J Hypertens 2000;13:17A–8A.
[2] Burt VL, Whelton P, Roccella EJ, Brown C,
Cutler JA, Higgins M, et al. Prevalence of hyperten-
sion in theUS adult population: results from the Third
National Health and Nutrition Examination Survey,
1988–1991. Hypertension 1995;25:305–13.
[3] National Institutes of Health. National Conference
on High Blood Pressure Education: report on
330 V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
proceedings. 1973. Bethesda, MD: Public Health
Services, Department of Health Education and
Welfare Publication (NIH) 73–486.
[4] The Pooling Project Research Group. Relation-
ship of blood pressure, serum cholesterol, smoking
habit, relative weight and ECG abnormalities to
incidence of major coronary events: final report of
the Pooling Project. J Chronic Dis 1978;31:201–306.
[5] JointNational Committee on Prevention.Detection,
Evaluation, and Treatment of High Blood Pres-
sure. The sixth report. Arch Intern Med 1997;157:
2413–46.
[6] American Heart Association. High blood pressure
statistics. http://www.americanheart.org/Heart_and_
Stroke_A-Z_Guide/hbp.html. Accessed April 11,
2001.
[7] U.S. Department of Health and Human Services.
Healthy people 2010: national health promotion
and disease prevention objectives. Washington, DC:
Government Printing Office; 2000.
[8] Roccella EJ, Burt V, Horan MJ, Cutler J. Changes
in hypertension awareness, treatment, and control
rates: 20-year trend data. Ann Epidemiol 1993;3:
547–9.
[9] National High Blood Pressure Education Program.
The National Heart, Lung, and Blood Institute
page. Available at: http://www.nhlbi.nih.gov/about/
nhbpep/index.htm. Accessed April 11, 2001.
[10] Williams PT, Fortmann SP, Farquhar JW, Varady
A, Mellen S. A comparison of statistical methods
for evaluating risk factor change in community-
based studies: an example from the Stanford Three-
Community Study. J Chronic Dis 1981;34:565–71.
[11] Farquhar JW. The community-based model of life
style intervention trials. Am J Epidemiol 1978;108:
103–11.
[12] Meyer AJ, Nash JD, McAlister AL, Maccoby N,
Farquhar JW. Skills training in a cardiovascular
health education campaign. J Consult Clin Psychol
1980;48:129–42.
[13] Maccoby N, Farquhar JW, Wood PD, Alexander J.
Reducing the risk of cardiovascular disease: effects
of a community-based campaign on knowledge and
behavior. J Community Health 1977;3:100–14.
[14] Fortmann SP, Winkleby MA, Flora JA, Haskell
WL, Taylor CB. Effect of long-term community
health education on blood pressure and hyperten-
sion control. The Stanford Five-City Project. Am J
Epidemiol 1990;132:629–46.
[15] Farquhar JW, Fortmann SP, Maccoby N, Haskell
WL, Williams PT, Flora JA, et al. The Stanford
Five-City Project: design and methods. Am J
Epidemiol 1985;122:323–34.
[16] Flora JA, Maccoby N, Farquhar JW. Commu-
nication campaigns to prevent cardiovascular
disease: the Stanford Community Studies. In:
Rice RE, Atkin CK, editors. Public communication
campaigns. Newbury Park, CA: Sage Publications,
1989. p. 233–52.
[17] Farquhar JW, Fortmann SP, Flora JA, Taylor CB,
Haskell WL, Williams PT, et al. Effects of commu-
nitywide education on cardiovascular disease risk
factors. The Stanford Five-City Project. JAMA
1990;264:359–65.
[18] Luepker RV, Murray DM, Jacobs Jr. DR, Mittel-
mark MB, Bracht N, Carlaw R, et al. Community
education for cardiovascular disease prevention:
risk factor changes in the Minnesota Heart
Health Program. Am J Public Health 1994; 84:
1383–93.
[19] Mittlemark MB, Luepker RV, Jacobs DR, Bracht
NF, Carlaw RW, Crow RS, et al. Community-wide
prevention of cardiovascular disease: education
strategies of the Minnesota Heart Health Program.
Prev Med 1986;15:1–17.
[20] Blackburn H, Luepker RV, Kline FG, Bracht N,
Carlaw R, Jacobs D, et al. The Minnesota Heart
Health Program: a research and demonstration
project in cardiovascular disease prevention. In:
Matarazzo JD, Weiss SM, Herd JA, Miller NE,
Weiss SM, editors. Behavioral health: a handbook
of health enhancement and disease prevention. New
York: Wiley and Sons: 1984. p. 1171–8.
[21] Jacobs Jr. DR, Luepker RV, Mittelmark MB,
Folsom AR, Pirie PL, Mascioli SR, et al. Commu-
nity-wide prevention strategies: evaluation design of
the Minnesota Heart Health Program. J Chronic
Dis 1986;39:775–88.
[22] Carleton RA, Lasater TM, Assaf A, Lefebvre RC,
McKinlay SM. The Pawtucket Heart Health Pro-
gram: I. an experiment in population-based disease
prevention. Rhode Island Medical Journal 1987;70:
533–8.
[23] Carleton RA, Lasater TM, Assaf AR, Feldman
HA, McKinlay S. The Pawtucket Heart Health
Program: community changes in cardiovascular
risk factors and projected disease risk. Am J Public
Health 1995;85:777–85.
[24] LefebvreRC,LasaterTM,CarletonRA,PetersonG.
Theory and delivery of health programming in
the community. The Pawtucket Heart Health
Program. Prev Med 1987;16:80–95.
[25] Winkleby MA, Feldman HA, Murray DM. Joint
analysis of three U.S. community intervention trials
for reduction of cardiovascular disease risk. J Clin
Epidemiol 1997;50:645–58.
[26] U.S. Department of Health and Human Services.
Fulfilling state priorities for prevention: The
Preventive Health and Health Services Block
Grant. Washington, DC: Government Printing
Office; 1998.
[27] National Center for Chronic Disease Prevention
and Health Promotion. Cardiovascular Health.
Available at: http//www.cdc.gov/nccdphp/cvd.
Accessed April 10, 2001.
[28] Fielding JE. Health promotion and disease preven-
tion at the worksite. Annu Rev Public Health
1984;5:237–65.
331V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
[29] Alderman MH. Hypertension control programs in
occupational settings. Public Health Rep 1980;95:
158–63.
[30] Alderman MH, Madhavan S, Davis T. Reduction
in cardiovascular disease events by worksite hyper-
tension treatment. Hypertension 1983;5(6 Pt 3):
V138–43.
[31] Foote A, Erfurt JC. Hypertension control at the
work site: comparison of screening and referral
alone, referral and follow-up, and on-site treatment.
N Engl J Med 1983;308:809–13.
[32] Logan AG, Milne BJ, Achber C. Work-site treat-
ment of hypertension by specially trained nurses.
A controlled trial. Lancet 1979;2(8153):1175–8.
[33] National High Blood Pressure Education Program.
At Massachusetts Mutual off-site care and good
monitoring reduce medical costs. RE: High Blood
Pressure Control in the Work Setting [Newsletter].
1980. Washington, DC: National Heart, Lung, and
Blood Institute.
[34] Lasater TM, Becker DM, Hill MN, Gans KM.
Synthesis of findings and issues from religious-
based cardiovascular disease prevention trials. Ann
Epidemiol 1997;7(S7):S46–S53.
[35] Hatch JW, Lovelace KA. Involving the south-
ern rural church and students of the health profes-
sions in health education. Public Health Rep 1980;
95:23–8.
[36] Hatch JW, Jackson C. North Carolina Baptist
church program. Urban Health 1981;10:710–71.
[37] Hatch JW, Voorhorst S. The church as a resource
for health promotion activities in the black com-
munity. Health Behavior Research in Minority
Populations: Access, Design, and Implementation.
Bethesda, MD: US Department of Health and
Human Services; 1992. NIH-NHLBI Publication
92–2965:30–33.
[38] Hatch JW, CallanA, Eng E, JacksonC. TheGeneral
Baptist State Convention Health and Human
Services Project. Contact, 77 1984; February.
[39] Eng E, Hatch J, Callan A. Institutionalizing social
support through the church and into the commu-
nity. Health Educ Q 1985;121:81–92.
[40] Bronner YL. Session II wrap-up: community-based
approaches and channels for controlling hyperten-
sion in blacks: barriers and opportunities. J Nat
Med Assoc 1995;87(Suppl 8):652–5.
[41] National Institutes of Health. Churches as an
avenue to high blood pressure control. Bethesda,
MD: National Heart, Lung and Blood; 1987. NIH
Publication 87–2725.
[42] American Heart Association. Search your heart, a
church-based heart health and stroke program [kit].
Dallas, TX: American Heart Association; 1997.
[43] EdmondsonB.UnclaimedbyGod.AmericanDemo-
graphics 1995;17:60.
[44] Castro FG, Elder J, Coe K, Tafoya-Barraza HM,
Moratto S, Campbell N, et al. Mobilizing churches
for health promotion in Latino communities:
Companeros en la Salud. J Nat Cancer Inst
Monogr 1995;18:127–35.
[45] Davis DT, Bustamante A, Brown CP, Wolde-
Tsadik G, Savage EW, Cheng X, Howland I,
et al. The urban church and cancer control: a
source of social influence in minority communities.
Public Health Rep 1994;109:500–6.
[46] Suarez L, Lloyd L, Weiss N, Rainbolt T, Pulley L.
Effect of social networks on cancer-screening be-
havior of older Mexican-American women. J Natl
Cancer Inst 1994;86:775–9.
[47] Kong BW. Community-based hypertension control
programs that work. J Health Care Poor Under-
served 1997;8:409–15.
[48] Kong BW. Community programs to increase hyper-
tension control. J Natl Med Assoc 1989;81(Suppl):
13–6.
[49] National Kidney Foundation. Healthy hair starts
with a healthy body [pamphlet]. Detroit, MI:
National Kidney Foundation of Michigan, 1999.
[50] Carter BL, Elliot WJ. The role of pharmacists in the
detection, management, and control of hyperten-
sion: a national call to action. Pharmacotherapy
2000;20:119–22.
[51] Carter BL, Barnette DJ, Chrischilles E, Mazzotti
GJ, Asali ZJ. Evaluation of hypertensive patients
after care provided by community pharmacists in a
rural setting. Pharmacotherapy 1997;17:1274–85.
[52] Erickson SR, Slaughter R, Halapy H. Pharmacists’
ability to influence outcomes of hypertension
therapy. Pharmacotherapy 1997;17:140–7.
[53] Mehos BM, Saseen JJ, MacLaughlin EJ. Effect of
pharmacist intervention and initiation of home
blood pressure monitoring in patients with uncon-
trolled hypertension. Pharmacotherapy 2000;20:
1384–9.
[54] Bogden PE, Abbott RD, Williamson P, Onopa JK,
Koontz LM. Comparing standard care with a
physician and pharmacist team approach for
uncontrolled hypertension. J Gen Intern Med
1998;13:740–5.
[55] Hill MN, Bone LR, Levine DM. Community Out-
reach. In: Oparil S, Weber MA, editors. Hyperten-
sion: a companion to Brenner and Rector’s Kidney.
Philadelphia: WB Saunders Co; 1999. p. 415–9.
[56] Robertson A, Minkler M. New health promotion
movement: a critical examination. Health Educ Q
1994;21:295–312.
[57] Miller NH, Hill MN. Nursing clinics in the
management of hypertension. In: Oparil S,
Weber MA, editors. Hypertension: a companion
to Brenner and Rector’s Kidney. Philadelphia: WB
Saunders Co; 1999. p. 409–14.
[58] Hypertension Detection and Follow-up Program
Cooperative Group. Five-year findings of the hyper-
tension detection and follow-up program. JAMA
1979;242:2562–71.
[59] Schron EB, Davey JA, Jensen JM, Probstfield JL.
The systolic hypertension in the elderly program:
332 V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333
implications for nursing practice and research.
Progr Cardiovasc Nurs 1989;4:138–45.
[60] Schultz JF, Sheps SG. Management of patients with
hypertension: a hypertension clinic model. Mayo
Clin Proc 1994;69:997–9.
[61] Hill MN, Miller NH. Compliance enhancement:
a call for multidisciplinary team approaches. Cir-
culation 1996;93:4–6.
[62] DeBusk RF, Miller NH, Superko HR, Dennis CA,
Thomas RJ, Lew HT, et al. A case-management
system for coronary risk factor modification after
acute myocardial infarction. Ann Intern Med 1994;
120:721–9.
[63] Friedman RH, Kazis LE, Jette A, Smith MB,
Stollerman J, Torgerson J, et al. A telecommunica-
tions system for monitoring and counseling patients
with hypertension: impact on medication adherence
and blood pressure control. Am J Hypertens 1996;
9(4 Pt 1):285–92.
333V.L.L. Welch, M.N. Hill / Cardiol Clin 20 (2002) 321–333