R E S P I R A T O R Y

N

on

I n

va

si v

e V e n t i l a t i o n

vylife® Boussignac1 device,3 ventilation modes

vylife® Boussignac

2 3

Proven interest of NIV-2P (5,6):

vylife® Boussignac, 1 device, 3 ventilation modes

CPAP mode

Non Invasive Ventilation with 2 levels of pressure

Continuous Positive Airway Pressure (one pressure level)

NIV-2P mode

COPD (Chronic Obstructive Pulmonary Disease) and Pneumopathy with hypoxemia

APE (Acute Pulmonary Edema)

1211109876543210

0 1 2 3 4 5 6 7 8

WOB

CPAP7.5 cmH2O

Spontaneousventilation

DELTA P

Time

cmH2O

Exp.

Insp.

9 10 11 12

DELTA P

Atmosphericpressure

Decreaseof venous return

Decreaseof left ventricular afterload

APE Hypoxemia CPAPmode

Alveolar recruitment

Improvment of ventilation /perfusion ratio

Decrease the WOB

Pulmonaryvolume

Hemodynamic

COPD, Pneumopathy

with hypoxemiaHypercapnia NIV-2P

mode

Decrease the WOB

Increase of tidal volumeIS

(Inspiratory Support)

Alveolar recruitmentPEP

(PositiveExpiratory Pressure)

Improvement of ventilation /perfusion ratio

Decrease the WOB

The Work Of Breathing (WOB)is the expenditure of energy required to inspire air in the lungs.

Delta Pis the difference between inspiratory pressure and expiratory pressure.

• Increased gazometric and ventilator parameters• Decreased morbidity and mortality• Decreased length of stay• Reduced risk of reintubation

12

11

10

9

8

7

6

5

4

3

2

1

0

-1

Insp.

Insp.

Exp.

Exp.

EPAP

Time

IPAP

cmH2O

Temps0

5

10

15

12

1 2

4

5 6

3

1 EPAP: Expiratory Positive Airway Pressure2 Inspiratory trigger3 IS (Inspiratory Support) = IPAP-EPAP4 Slope: speed from expiratory pressure to inspiratory

pressure5 IPAP: Inspiratory Positive Airway Pressure6 Expiratory triggerIPAP : Inspiratory Positive Airway Pressure

EPAP : Expiratory Positive Airway Pressure

Respiratory cycle in NIV-2P

APNEA mode

Return to spontaneous ventilationfollowing cardiac arrest

Mechanical ventilationAPNEA Mode

Transport of intubated patient

Proven interest of CPAP:

Interest of mechanical ventilation:

• Pressure control• Physiological mechanical ventilation: in open system, lung elastance and compliance regulates the speed and volume of gas

• Proven efficiency in the management of acute pulmonary edema (1,2)

• Avoids the need for tracheal intubation (3)

• Cost/benefit ratio shows a positive result in favour of CPAP in pre-hospital medical care (4)

vylife® Boussignac

4 5

3 Easy to use

• vylife® Boussignac starts with the chosen mode of ventilation and pressures• Adjustable pressure with buttons “+” and “-”• Inspiratory Support (IS)=IPAP-EPAP• Portable• Capnograph connection via interface or manometer port

1 Effective

Mode VNI-2P (10, 11)

• Pressurisation quality• Accurate trigger

CPAP mode (7,8)

• Flow rate of gas available for inspiration is 280 to 320 l/min• The difference between inspiratory pressure and expiratory pressure (Delta P) is only1.5 +/- 0.2 cmH2O (9)

• Regulation of inspired FiO2

2 Safevylife® Boussignac is an open system, if necessary the patient can breathe atmospheric air and thus constantly breathe the required volume of gas.The pressure in the lungs cannot be superior to the virtual valve (A):

Oxygen accelerationOxygen supplyOxygen molecules arrivein the chamber

The oxygen molecules collide with each other,generating turbulence which transforms the speedinto pressure

The oxygen molecules are acceleratedat the speed of sound when they pass troughfour micro-channels

The oxygen molecules strike a deflectorwhich sends them back to the central zone(mixing zone)

Pressure monitoringor administration of additional oxygen or EtCO2 monitoring

Oxygen breaking

Creation of a virtual valve

Pressure (A)

Pressure directlydepends on

flow rate of gas

When you increase the flow rate,you increase the pressure

When you decrease the flow rate,you decrease the pressure

Flow rate of gas available280 – 320 L/min

Open toatmosphere

No risk of barotrauma / volotraumaNo risk of hypoventilation

vylife® Boussignac: all the advantages of Boussignac CPAP + a trigger

Open system: no risk of asphyxia

Special “star”shaped O2 tube: Thanks to this design, the patient will always get O2 even if the tube is kinked

Large screen: Easy to read (ventilation mode,pressures, battery, respiratory frequency)

One click connection:no risk of misconnection

Disposable kit: ready to use

Easy to use:+ increases pressure- decreases pressure

www.vygon.com

References

(1) Hubble Mw, and al. Effectiveness of continuous positive airway pressure in the management of acute pulmonary edema. Prehosp Emerg Care. 2006;10:430-439(2) Gray A et al. Noninvasive ventilation in acute cardiogenic pulmonary edema. N Engl J Med. 2008;359:142-151(3) Wang He, and al. Medical conditions associated with out-of-hospital intubation. Prehosp Emerg Care. 2011;15:338-346(4) Hubble MW, and al. Estimates of cost-effectiveness of prehospital continuous positive airway pressure in the management of acutepulmonary edema. Prehosp Emerg Care. 2008;12:277-285(5) Meduri Gu and al. Noninvasive positive pressure ventilation via face mask. First-line intervention in patients with acute hypercapnic and hypoxemic respiratory failure. Chest 1996 Jan;109(1):179-93(6) Ram FS and al. Non-invasive positive pressure ventilation for treatment of respiratory failure due to exacerbations of chronic obstructive pulmonary disease. Cochrane DatabaseSyst Rev. 2004;(3):CD004101(7) Templier F and al. Ann Fr Anest Reanim 2003 ;22 :103-7(8) Lyazidi A and al. Evaluation des systèmes à Pression Positive Continue (CPAP) sur banc d’essai. Hôpitaux Universitaires de Genève(9) P. Valero MD, A. Khoury MD, G. Capellier MD, Phd, D. Robert MD, Phd. Comparison between 3 devices delivering Continuous Positive Airway Pressure (CPAP). Poster(10) Brochard L. et al. Evaluation d’un nouvel appareil de ventilation assistée portable : la Vylife Boussignac. Poster SRLF 2009(11) Jaber S. et al. Un nouveau ventilateur «léger», la Vylife - BiPAP Boussignac : évaluation sur banc test. Poster SFAR 2012

AU

GU

ST 2

013

/ DB

CPA

P 13

207

E

Complete range

vylife® kit without harnessCodes 5567.303 / 403 / 503 / 603

Oxygen extension tubeRinged tubeCPAP BoussignacFiO2 ringTriggerFacial mask

Codes 5582.802 (AFNOR)

2 vylife® kits

1 vylife® charger

1 vylife®device1 Rapid instructions for use1 Oxygen stopcock

Codes 5582.700 (without Oxygen stopcock)

2 vylife® kits

1 vylife® charger

1 vylife®device1 Rapid instructions for use

vylife® kit with harnessCodes 5568.303 / 403 / 503 / 603

Oxygen extension tubeRinged tubeCPAP BoussignacFiO2 ringTriggerFacial mask

Single use kit

O2 vylife® kit

5568.303 / 403 / 503 / 603 5568.303 / 403 / 503 / 603

Vygon – 5, rue Adeline • 95440 ECOUEN • FRANCEReception: +33 (0)1.39.92.63.63 – Service clients France: +33 (0)1.39.92.63.81Export customer service: +33 (0)1.39.92.64.15Fax: +33 (0)1.39.92.64.44 • www.vygon.com

For further information, please contact: questions@vygon.comThe specifications shown in this leaflet are for information only and are not, under any circumstances, of a contractual nature.