Scientific collaboration has always been a hallmark of the Diabetes Research Institute,where an open-door philosophy and willingness to share new findings has changed the international research paradigm. Today, these strategic alliances are playing an increasinglycritical role in the effort to cure diabetes by opening up new doors of discovery and aggregating expertise in key research areas.

“We actively seek partners who bring unique talents to the table, regardless of where theirbase institutions may reside, with each contributing simultaneously to answer a criticalquestion that is perhaps unanswerable unless we all work together,” says DRI Scientific Director Camillo Ricordi, M.D.

Accordingly, the DRI hosted several leading scientists over the last few months who cameto Miami to present their latest findings and join together on novel research initiativesaimed at re-educating the immune system and restoring tolerance, and increasing cellsupply. Below is a summary of the projects that were shared during their visit:

Reactivating Insulin-Producing Cells

Bart Roep, M.D., Ph.D., of Leiden University Medical Centre in Leiden, Netherlands, has recentlydemonstrated that islet cells may be reactivated, even years after the initial diabetes diagnosis.His recent study refutes the long-standing belief that those with type 1 have no insulin-producingcells left at all. It seems that many people do have the cells, although the cells are not active.

Dr. Roep, whose research focuses on developing immunological intervention strategies in type1 diabetes, has developed methods to identify and study white blood cells that are involvedin the destruction of the islets. Further studies will focus on developing a vaccine that

DRIfocus

DRI Foundation VP TomKarlya, a.k.a. DiabetesDad, made the cover of Diabetes Healthmagazine.

> Article on page 2

Actor Jake T. Austin, bestknown for his role in theDisney Channel’s Wizardsof Waverly Place, attendedLong Island's Kids Partyfor a Cure.> Article on page 14

Music legend Barry Gibbonce again entertainedthe DRI family at the38th Annual Love andHope Ball.

> Article on page 17

Chef Emeril Lagasseadded his essence at the American Fine WineCompetition Gala.

> Article on page 18

In Memory of Robin GibbThe Diabetes Research Institute andFoundation mourns the loss of one ofour family members, Robin Gibb. Alongtime supporter and member of ourHonorary Board of Directors, Robin reunited on stage with older brotherand Bee Gees bandmate Barry Gibb fora spectacular concert at the 2006 Loveand Hope Ball (pictured). Our hearts goout to the Gibb family and to everyonewho loved Robin.

Miami / New York / Long Island / California / Washington, D.C.

A Family Affair Emeril Dishes

Join us on social media!

Idol Action

American Idol season ninerunner-up Crystal Bowersoxperformed at the Walkwith Walgreens FamilyFun Day & Health Fair.

> Article on page 15

Continued on Page 11

Cover Dad A Magical Afternoon

Diabetes Research Institute Foundation Spring 2012 / Volume 39 / Issue 2

DRI AND PARTNERS EXPLORE NEW INITIATIVES,AIM TO FAST-TRACK FINDINGS

DRIF’S TOM KARLYA GRACES DIABETES HEALTH COVERDRIF Vice President Tom Karlya is known ubiquitously by his penname, Diabetes Dad. Thousands of people check in to read his columnon dLife and follow his quirky and inspirational posts on Facebook.Now, even more will read his article, “Don’t Do Nothing,” and see avintage photo of Tom with his daughter, Kaitlyn, as a little girl as itgraces the cover of Diabetes Healthmagazine.

In the article, Tom first states his connection to diabetes: Kaitlyn wasdiagnosed with type 1 at age 2 in 1992; his second of three children,Rob, was diagnosed at age 13 in 2009. He then speaks directly toparents about how to “navigate through the maze of diabetes.”

Tom offers advice on how to find friends online and talks about

the benefit of summer camp. He encourages families to attend theChildren With Diabetes annual conference, Friends for Life, in Orlando, FL, slated for July 3-8, 2012.Most importantly, he informs readersabout the DRI’s cure-focused missionand makes a push for parents to getinvolved, or “Don’t Do Nothing,” ashe aptly puts it.

Please visit DiabetesResearch.org/DiabetesDad.

With great sadness, the Diabetes Research Institute and Foundation mourns the loss of adear friend and National Board member,Mark H.Ayers. He was the president of the Building andContruction Trades Department (BCTD), whichis the largest contributor to our organization.

Mark was a labor leader of vision, innovation,passion and integrity, and it was through hisleadership that North America's BuildingTrades Unions are on the path to success and increased market share for the unionconstruction industry.

Although our hearts are heavy, our spirits arelifted by virtue of the unsullied legacy of aworking man who was grounded and guidedto his core through the values that were instilled in him during his upbringing in Peoria,IL. Mark was a true trade unionist in everysense of the word, and it was through that

commitment to bettering the lives of workingfamilies that he was able to offer so much to hiscountry, his family, and to the labor movement.

Mark’s dedication to the Diabetes Research Institute was also strong-felt and unwavering.He subscribed to a belief that “tough timesnever last, but tough people do,” and when theeconomy took a downturn, Mark announced thatthe BCTD would reconfirm their support witha gift of $5 million in 2010. He was resolutewhen he said of their tireless support, “We’vecome too far to turn back now.”

“Mark was a good friend and a great leader,”said Robert A. Pearlman, president and CEO ofthe DRI Foundation . “He led with vision andhonesty, and he will remain in our hearts for a long time to come. Our thoughts are withhis family and so many others who loved andrespected him.”

The Diabetes Research Institute Foundation is pleased to announcethe appointment of two new members to its regional boards inFlorida and the Northeast.

Sabrina Ferris of Miami, FL, joined the Florida Regional Board recentlyand kicked-off her service by becoming one of the top two fundraisers atthe Walk with Walgreens Family Fun Day & Health Fair. She is committedto finding a cure for her son, Colby, 6, who was diagnosed with type 1diabetes in the beginning of 2010. With her husband, Scott, andolder son, Sage, 9, Sabrina's family have immersed themselves intosupporting the DRI’s cure-focused mission. They have attendedfundraising events, and Sabrina even served as the evening’s speakerat the last Love and Hope Preview Party.

“We found great comfort at the DRI,” she said. “Everyone there is sowarm and welcoming. We truly feel like part of a family. We know…hope…believe the DRI will find a cure.”

A University of Miami alumnus, Sabrina is a shareholder with GreenbergTraurig in Miami. As a trial lawyer, she focuses her practice on productsliability and complex commercial litigation in federal and state courts.She has litigated matters involving fiduciary relationships, products liability, contract disputes, shareholder disputes, securities transactions,employee non-competition agreements, fraud and insurance claims.She has earned numerous professional and community achievements

and was listed as one of “40 Under 40” in the South Florida BusinessJournal in 2011 and as a “Rising Star” in Super Lawyers in 2009.

Bonnie Inserra of Mahwah, NJ, recently joined the Northeast RegionalBoard and has been a National Board member since 2009. She is theexecutive director and a benefactor of the Inserra Family Foundation.She serves on the boards of the Hackensack University Medical CenterFoundation and Tomorrow’s Children, as well as on the Advisory Boardof Columbia Presbyterian Babies Hospital for Hope and Heroes. She alsoserves on the board for The Colleen Giblin Foundation, an organizationfrom which Bonnie received the personal honor of becoming the firstrecipient of the Woman of the Millennium Award, in addition to receivingthe Humanitarian of the Year Award for the Inserra family.

A staunch advocate for medical research, Bonnie is especially knowledgeable about diabetes and cancer. Her son, Lawrence, is a 20-year cancer survivor. Her commitment to the DRI began after herdaughter, Lindsey, was diagnosed with a difficult-to-manage form of type1 diabetes at age 11. Due to Bonnie’s tireless pursuit of revolutionarymedical treatment to save her daughter’s life, Lindsey has directlybenefited from groundbreaking research and developments, as shewas the first child in the world to use the Mini Med Intra-PeritonealImplanted Pump.

3 |

A Messagefrom the Chairman

Dear Friends,

In this issue of DRIFocus, we pay tribute to many remarkable individuals,including two men whose lives were taken far too prematurely.

As you read on the cover, the DRI and Foundation, as well as theworld, lost a treasured legend when Robin Gibb of the Bee Gees succumbed to a challenging illness. Our thoughts and prayers arewith his brother, Barry, who, together with his wife, Linda, serve asInternational Chairmen of our Love and Hope committee, and his entirefamily at this sad time. Many of you have been fortunate to attendtheir private performances at our Love and Hope galas and thosememories will live on in our hearts.

Our DRI family also mourns the passing of National Board MemberMark H. Ayers, who served as president of the AFL-CIO Building andConstruction Trades Department, our most significant contributor.Mark was a man of high integrity and uncompromising principles,who championed the DRI’s efforts to find a cure. He recognized howdeeply diabetes affects patients and their families, including countlessunion members, and he was passionately committed to ending theirsuffering. He was a dear friend and will be truly missed by all of us.

In the wake of our sadness, we cannot dim the brightness of the futureand those who are shining examples of unrelenting dedication.Throughout these pages, you’ll read about our supporters who aredoing great things to bring us closer to cure for diabetes.

Among them is Isabel May (page 8), who recently celebrated her 100thbirthday and still remains an active supporter of the DRI Foundation,among other organizations. Isabel’s continuing generosity, along withour other major donors, provides a critical base of support for the DRI.

Ron Darling, one of our National Board members whose name maybe familiar as a NY Mets superstar, is “obsessed” with ensuring thatour DRI scientists have the resources they need to find a cure for hisson and millions of others with diabetes. Through his foundation,Ron has helped to raise tens of thousands of dollars for the DRI, whilecementing a wonderful fundraising partnership with McFadden’sRestaurant and Saloon at Citi Field (page 8).

Another father taking action for his son is Kevin McGurgan, one ourDiabetes Diplomats who is a genuine diplomat. Kevin, who serves asBritish Consul-General in Miami, was inspired by the SummerOlympics taking place in his homeland and is running 12 races in 2012to benefit the DRI. You can read about his story and those of ourother Diabetes Diplomats on page 5.

And, there is the DRIF’s own Diabetes Dad, Tom Karlya, who is featuredon the cover of the April/May issue of Diabetes Health magazine.Tom, who has two children with type 1, urges parents to reach out toothers, help their kids succeed and support the DRI.

Many families are finding support through our PEP Squad (ParentsEmpowering Parents). Whether attending our mini-conferences orreaching out to others on our PEP Squad Facebook group, parents like JenYedo (page 12) are finding hope, inspiration and a dose of good ideas.

Patients and parents alike are getting involved throughout our regionsand around the country through our many events, as leaders and par-ticipants. We thank each and every one of you for your tireless efforts.

Everyone involved with this organization is providing the vital fundingneeded to further our research toward a cure, like the work of Dr.Chris Fraker (page 9). Dr. Fraker, who has type 1 diabetes himself, hasconducted ground-breaking studies on the critical need for oxygenby insulin-producing cells and is working together with our other scientists to build on these promising findings.

From our board members and countless loyal supporters to our DRIscientists and Foundation staff, we are all accomplishing great thingsfor those living with diabetes. Thank you again for all that you do tosupport our cure-focused mission.

Sincerely,

Harold DoranChairman of the Board

1. Sabrina Ferris, 2. Bonnie Inserra.

NEW DIRECTORS JOIN REGIONAL BOARDS

21

3 |

IN MEMORY OF MARK H. AYERS

Retirement planning is ahot topic that’s becominghotter as 77 million babyboomers prepare to enterand perhaps redefine retirement. For many individuals, retirement assets may comprise thelargest component oftheir estates. While justabout all of us have become concerned withthe accumulation of retirement assets, far toofew of us have thoughtabout the ultimate distri-bution of those assets andtheir tax consequences atthat time.

For those whose retirementassets have grown sub-

stantially over the years, charitable gift planning may offer an attractive alternative to having the assets depleted by taxes. A planned gift to the Diabetes Research Institute Foundation mayreduce or eliminate those taxes and, at the same time, better provide for family members. The key is to integrate your givingwith your overall financial and estate planning.

The following are some of the most frequently asked questionsthat we receive regarding the use of retirement assets for charitablegift planning:

Why are retirement assets subject to income taxes for heirs?The tax law classifies retirement assets such as traditional IRAs,401(k), 403(b) and Keogh plans as income in respect of a decedent(IRD), which refers to assets that would have been taxed as incomehad the decedent lived to receive them. Left to family members orfriends, retirement assets are subject to income tax, may also besubject to estate tax, and if given to grandchildren, could also incurthe generation-skipping transfer tax (GST). The combined taxes

could deplete the retirement account by as much as two-thirds.

How can I integrate charitable gifts of retirement assets with myfinancial and estate planning?Because of the potential multiple layers of tax that your familymay incur, retirement plan assets may be particularly attractive asan asset to leave to the DRI Foundation. If you designate the DRIFoundation as a beneficiary upon your death of all or a specifiedpercentage of a retirement plan, the portion of the plan payable tothe Foundation will generally escape estate taxes, and the Foundation,as a tax-exempt institution, will not be required to pay income taxon the distributions. As a general rule, if you intend to make bothnon-charitable and charitable gifts at death, it makes sense to consider using your tax-deferred retirement plan assets for charityand other assets, such as appreciated securities, for heirs.

How do I donate retirement assets?The easiest way to donate retirement plan assets is to designatethe Diabetes Research Institute Foundation as a beneficiary. Youcan contact the administrator of your plan and they will send youthe correct forms to sign. If you are married, your spouse mustwaive his or her right to survivor benefits from the plan (not thecase for IRAs). When you designate the DRI Foundation as a beneficiary,as with a charitable bequest, you have considerable flexibility. Youcan give a specific amount to us, or a percentage to us and otherbeneficiaries. You can name your spouse as the primary beneficiaryand the DRI Foundation as the secondary beneficiary. Another way togive from your retirement account is to have those assets transferredat death to a charitable remainder trust (CRT) with the remainderinterest going to us, but only after the termination of all income rights.If the beneficiary of the CRT is a spouse, it is possible (by combiningthis strategy with the unlimited marital deduction) to eliminate allfederal estate taxes attributable to the retirement account.

Can I make a gift to the DRI Foundation from my retirement accountduring my lifetime?Yes – if you are over age 59 ½, you can make withdrawals from yourretirement plan and contribute the amount withdrawn to the DRIFoundation. You can fully deduct it as a charitable gift and you willnot owe federal income tax on the amount donated. You will alsohave removed the amount from your estate.

RUNNING…DANCING…CREATING A CURE!

British Consul-General Kevin McGurgan of Miami, FL, was inspiredby the 2012 London Summer Olympics when he decided to run 12Races in 2012 in South Florida and throughout the country. Everydrop of sweat is mixed with the love Kevin has for his 7-year-oldson, Michael, who was diagnosed with type 1 diabetes at age 2, andthe hope he found at the DRI while touring the labs. So far he hasraised $4,332.

“Diabetes has changed our lives completely,” Kevin said. “I’ve neverdone anything like this. I’m just a regular guy who likes to exerciseand I decided to take it to another level.”

Sharing his sentiment in Virginia Beach, VA, is Aimee Curley.Though she has run half marathons in the past, Aimee felt that it would be appropriate to take on her first full marathon – the 40th Yuengling Shamrock Marathon – at age 40. She visited DiabetesResearch.org/DiabetesDiplomats and learned how to easily create a fundraising page. There she uploaded a photo of 15-year-old Shaelyn West, “my incredible niece who was diagnosedwith type 1 diabetes at age 3.” Friends and family members madedonations online that exceeded $5,500, and as Aimee ran 26.2miles on March 18, she silently gave thanks to each one.

Also in the Northeast, while Tara Byrnewas preparing to graduateearly (as a junior) from Warwick Valley High School in Warwick, NY,she was also organizing a Diabetes Dance Marathon to benefit theDRI. Held on May 19, the 12-hour event attracted 300 teens fromthroughout Orange County and raised more than $10,000. Tara became instantly dedicated to the cause after her step-father said

to her, “Some people joke that they would give anything for cash ora new car, but I rea lly would give anything – an arm or leg – to livea day without [type 1] diabetes.”

In Philadelphia, PA, another parent-child conversation revolvedaround a day spent at the DRI. For 11-year old Jonathan Berman, itwas “the best day of my life so far!” Motivated by the excitementand hope he witnessed in the labs, Jonathan and his family createda “store for a cure” at www.cafepress.com/curet1d, where creatived-centric flip-flops are available for sale to benefit the DRI.Jonathan encourages everyone to “Have fun in the sun this summer in our custom-designed flip flops and let your feet raiseawareness for a cure!”

Another Diabetes Diplomats initiative powered by creativity isKlips for a Cure, based in Daytona Beach, FL. Klips are decorativehair accessories handmade by teen Hannah Klippel, who has type 1diabetes, and her mother, Susan, and sold for a donation between$1 and $3. With a goal of raising $5,000 for the DRI, so far TeamHannah’s Hope has raised more than $1,600.

These Diabetes Diplomats make it clear that running, dancing andcreating are feasible ways to help the DRI move closer to a cure.What are your hobbies? Let us help you turn them into a DiabetesDiplomats project! Contact Tom Karlya at tomkarlya@drif.org or findout for yourself how easy it is to create your own fundraising pageat DiabetesResearch.org/DiabetesDiplomats. Just don’t do nothing!

Serving as advocates, educators and event fundraisers in their schools and communities, people from all over the world are participatingin the DRI Foundation’s Diabetes Diplomats program. Even an actual foreign diplomat has joined the ranks of these individuals dedicatedto helping the DRI find a cure!

The calendar year 2012 may turn out to be one of the best years for making a gift to the Diabetes Research Institute Foundation during yourlifetime. Despite continued uncertainty in the tax laws, donors will have some unique opportunities to make charitable gifts this year. Hereare some of the highlights:

• The lifetime gift tax exemption is $5.12M for individuals (up from $1M) and $10.24M for married couples (up from $2M). The estate taxexemption also increased to $5.12M.

• The unified credit, which integrates the federal gift tax and estate tax into one unified tax system, enables you to give away $5.12 millionduring your lifetime without having to pay gift tax.

• There are a number of ways that you can transfer assests to your children, grandchildren or other people that you wish to make gifts tothat qualify for the current exemption amounts while also enabling you to make a charitable gift to advance the DRI’s most promisingcure-focused research. For more information, please contact Jill Shapiro Miller, vice president of Gift Planning, at jshapiro@drif.org or at(800) 321-3437. For more details on the tax law in 2012, please visit DiabetesResearch.org/TaxLawUpdate.

ARE YOU AWARE OF HOW THE 2012 TAX LAW AFFECTS YOU?

Charitable planning with retirement assets isone of the best ways to help bring us closerto a cure.

HOW GIFTS FROM RETIREMENT PLANSBENEFIT THE DRI AND YOUR FAMILY

5 |

1. British Diplomat Kevin McGurgan in Miami, FL, is also a Diabetes Diplomat, running 12 Races in 2012 in honor of his son, Michael., 2. Aimee Curley participatedin her first marathon in honor of her niece, Shae, in Virginia Beach, VA., 3. Tara Byrne, president and founder of Diabetes Dance Marathon, raised thousandsin Warwick, NY., 4. At the DRI Jonathan Berman gave a “high five for a cure” to Gary Kleiman, DRI and Foundation senior director of Medical Development.Back home in Philadelphia, PA, he created flip flops for a cure!, 5. In Daytona Beach, FL, the Klippel family created Klips for a Cure, a Team Hannah’s Hope initiative.

1 2 3 4 5

FOUNDATION DONORS RECOGNIZED

PERPETUATION AWARD: Larry Inserra accepted on behalf of The InserraFamily with DRI’s Scientific Director Dr. Camillo Ricordi and DRIF’sPresident and CEO Robert A. Pearlman(1).TRANSLATION AWARD: Roy Ripak accepted on behalf of Walgreens of South Floridawith DRIF’s Tom Karlya (2). REALIZATION AWARD: Bianca and Vince Wilfork of the New EnglandPatriotswith DRIF's Brian Huether (3).EXPLORATION AWARD: Lucy Carter and Ted Moudis of Ted MoudisAssociates, Inc. (4), Shelley and Steven Deutsch (5), Lisa and DavidDesmond with DRIF’s Pearlman and Deborah Chodrow (6), StanDoobin of Harvard Maintenance, Inc. (7), Tammy and Steven Klein(8), Allan and Louise Pashcow (9)HYPOTHESIS AWARD: John Gutleber, Deidre Costa-Major, Frank andRita Castagna representing Americana Manhasset with LI Boardmember Barbara Hatz (10), David and Iris Feldman (11), Jim Guy (12),RichardWood of Plaza Construction Corporation (13).QUERY AWARD: Kaye Garcia of the Forest County Potawatomi Foundationwith National Board member Glenn Kleiman (14), Jilland Robert Rosenhaus (15), Wendy Waller (16)

Awards from the DRI Foundation’s Cycle of Discovery series were presented to donors who recentlymade major gifts. The award program corresponds with the Foundation’s cumulative giving des-ignations. Awards were presented individually and at various events, including a lovely holiday re-ception at the Muttontown Club in Long Island and a post Empire Ball committee reception at theGrand Hyatt Hotel in New York City.

10

4

9

1615

86 7

21 5

Visionaries $10,000,000+ InnovationChairman’s Council $5,000,000+ ValidationLeadership Council $1,000,000+ PerpetuationGovernors’ Society $500,000+ TranslationDistinguished

Humanitarians $250,000+ RealizationGrand Founders $100,000+ ExplorationFounders $50,000+ HypothesisBenefactors $25,000+ Query

DONOR LEVEL AWARD

1412 1311

7 |

3

9 |

Over the last several years, the Diabetes Research Institute has shown the extraordi-nary potential of cell replacement therapyto restore insulin function. While progresshas been substantial, islet transplantation,one of the methods being pursued, remainsan experimental procedure and we areworking to overcome the remaining challenges that limit its widespread use.

One of the major challenges is to identifynew sites in the body in which to transplantthe cells, as the liver is no longer thought tobe an optimal environment. Our goal at theDRI is to identify sites that closely mimic thenative environment of the pancreas to givetransplanted insulin-producing cells thebest chance at long-term survival. The avail-ability of oxygen will be key to creating anoptimized site; islets make up only 1-2 per-cent of the entire pancreas where they re-side, yet they use almost 25 percent of theoxygen that flows through the organ.

At the DRI, we are developing ways to deliverthat level of oxygen to the islets. We arealso testing several strategies to deliver thevital oxygen levels more effectively to stemcells as they mature into insulin-producingcells. Achieving the required amounts ofoxygen is critical in our efforts to restorenatural insulin production.

At the center of much of this work is Dr.Chris Fraker, research assistant professor of surgery and cell transplantation at the Diabetes Research Institute, who has spearheaded many cutting-edge initiativesaimed at curing diabetes for both professionaland personal reasons.

Q. For you, this work is personal, isn't it?A. Yes. I was diagnosed with type 1 diabetes

on my 16th birthday. Today, 26 years later,I'm starting to develop low-level complica-tions and my children have the markers forthe disease. So, as you can imagine, I'm motivated to find a cure.

Q. How does your work at the DRI impactcure-focused research? A. Islet cells need a lot of oxygen to effectivelysense glucose and produce insulin. So whenwe harvest islets from a donor pancreas ordevelop insulin-producing cells in the lab,we need to make sure we're providing thosecells with an oxygen-rich environment sothey can survive and function. Withoutadequate oxygen, some cells will die beforethey can even be transplanted. Or worse,cells that are transplanted may not survivetheir first few days post transplant; a criticaltime when blood vessels are still formingthat will naturally carry oxygen to the cells.So providing an oxygen-rich environment isvital, both in terms of developing a supplyof cells for transplant and in the survival ofthose cells immediately following transplant.

Q. How is the DRI using oxygen to increasethe supply of insulin-producing cells?A. Stem cells represent one of the mostpromising sources of insulin-producing cellsfor transplant, since they have the potentialto become any type of cell. In the lab, we'veshown that oxygen plays a major role in theprocess of transforming stem cells into insulin-producing cells. We developed and patenteda device called the "oxygen sandwich" toprovide maturing stem cells with an oxygenenvironment that’s more like the nativepancreas, compared to traditional plasticculture containers. In testing, cells in thesandwich produced an increase in insulin geneexpression in precursor cells that was several

times higher than control precursor cells.

Q. Once insulin-producing cells are transplanted, how is the DRI using oxygento enhance the cells' chances of survival?A. During the first few days after transplant,cells are under a tremendous amount ofstress; they're subject to inflammatory reactions and immune attack. We're usingoxygen to help create environments thatwill shield the cells.

At the DRI, we’ve been working to optimizecell encapsulation technology – the processof coating the cells with a protective shieldso they go unnoticed by the immune system.Early in my career here, I worked with the lateDr. Marcos Mares-Guia, a Brazilian researcherwhose encapsulation work laid the ground-work for some of our recent efforts.

We've come a long way since that time, further developing the Tissue Engineeringprogram at the DRI and building upon thisearly work and using new, biocompatiblematerials. Recently, my colleague Dr. AliceTomei developed a type of coating that literally conforms to the unique size andshape of each islet. This “conformal coating,”as it’s called, allows the implanted islets togo unnoticed by the body and avoid an inflammatory reaction, yet still allows oxygenand other nutrients to easily reach the cell.

Now we’re taking that research a step further.I'm working with her to develop coatingmaterials that could potentially generateoxygen, which I hope will give the islets aneven greater chance to thrive.

I also worked with the DRI's Dr. Cherie Stablerin her lab, developing a novel biomaterialand a method to deliver a slow but steadystream of oxygen to cells. This material has

UNDER THEMICROSCOPE

with Chris Fraker, Ph.D.

Back in the day, Ron Darlingwas a high-profile, right-handed pitcherfor the New York Mets. He debuted in Major League Baseball in 1983,won the 1986 World Series and played his final game in 1995. Heremains in the spotlight as a color commentator for national baseballcoverage and has won an Emmy Award as “Best Sports Analyst.”But all that is secondary to his life’s one true mission – to find a curefor diabetes for his son, Jordan, 18, and the millions affected by it.

“I wanted to align myself with an organization where I thought peoplewere doing great work – not good work – but great work, and I waslooking for a place that was focused on a cure,” Ron recalled. “Whenyour child is sick, you try to educate yourself with the latest research.I came across the brilliant work being conducted at the DiabetesResearch Institute, and I am obsessed with making sure these scientists have the access to funding that they need to completetheir work.”

Through his foundation, Ron has helped raise tens of thousands ofdollars for the DRI. This past December, he hosted his second TexasHold'em Tournament and Casino Night at Leonard's of Great Neck onLong Island. Currently, the Ron Darling Foundation has teamed upwith McFadden’s Restaurant and Saloon at Citi Field. All season long,restaurant patrons will have the opportunity to enter the McFadden’sSports Fan of the Month contest by making a donation. Everyonewho contributes $5 or more will be entered into the drawing. Eachmonth, one generous donor will receive: four of Ron’s personal ticketsto a game, access to batting practice and a booth visit with Ron(Learn more at DiabetesResearch.org/McFaddens).

“We’ve been lucky enough to partner with McFadden’s to help usreach out to Mets fans. It’s this kind of sexy idea that helps us notonly raise money but create awareness,” said Ron, who confessedhe didn’t know much about diabetes prior to Jordan’s diagnosis.

“I got that call,” he remembered. “I was on the other coast, and hismother brought him to the hospital. It was a shock to all of us. It was scary for Jordan, who was 11 at the time. But he is very intelligent, and he just got it. He knew what to do, and he’s beenvery independent.”

Ron continued, “Jordan is a gifted athlete, but he consciously decidedthat with everything on his plate, he couldn’t pursue the sportsthing. And he’s found a different outlet. He turned to music, and Ialways found that incredibly strong. He’s a pianist, a guitar player,and he writes his own music. He’s pretty brave,” said Ron poignantly,in the voice of a proud father who desperately wants a cure for his son.

“I want to say to my son one day, ‘Jordan, all the money we raised…all the good deeds we did…have found you a cure.” That’s exactlywhy Ron joined the National Board of Directors for the DiabetesResearch Institute Foundation and visited the world-renownedcenter in Miami to learn firsthand about the DRI’s vital research.

“The DRI is a cutting-edge facility. Once I visited, I was sold. Eversince, I’ve been trying to help in any way that I can.”

Story continues on page 11.

Isabel May recently celebrated her 100thbirthday. Still active and extraordinarily generous to many charitable causes, the Diabetes Research Institute is honored to be one of her favorite organizations.

Isabel has been involved with the DRI formore than three decades through the Loveand Hope Committee. Life Chairman SonjaZuckerman reached out to her and invited herto attend one of the Love and Hope Balls, andsoon she began taking a much more activerole, serving as the Preview Party Hostess for more than 10 years, and this year as theHonorary Chairman of the Ball.

Born in Brooklyn and residing on Long Island for many years, Isabel and her late husband,Sam, were originally snowbirds, and eventuallymoved to Miami Beach. Sam was a CPA, andset up a practice in Florida.

Isabel was a social worker with the Brooklyn Department of Welfareby profession and a “people person” by heart. Following in her

mother's philanthropic footsteps, Isabel said, “I’ve tried many things…knitting, sewing…but I really enjoy being with people...so you cansay that charitable organizations were my hobby.”

Isabel had a special piece of furniture built so she could display thenumerous awards she has been given over the years in recognition ofher generosity. While she didn’t make these contributions for thispurpose, it reminds her, and those who visit her, about the importanceof philanthropy.

Sam was diagnosed with diabetes as he got older, so Isabel knowsfirst-hand about living with it, but she is particularly compassionatewhen it affects young children.

Isabel has two children – a son who lives in Manhattan with hisfamily, and a daughter who splits her time between Long Island andPlantation. She also is a proud grandmother of five, and a great-grandmother of 10. They all recently joined her to celebrate her veryspecial birthday.

A member of the DRI Foundation’s prestigious Governors’ Society, Isabel has contributed over half a million dollars to help fund researchthat she believes will lead to a cure for this devastating disease.

Ron Darling and his son, Jordan, are hoping a new partnershipwith McFadden's at Citi Field will raise funds for the DRI!

BASEBALL GREAT RON DARLINGPITCHES IN TO SUPPORT THE DRI

The DRI family thanksIsabel May for herfriendship, caring andkindness.

100 YEARS YOUNG... AND A LEGACY OF PHILANTHROPY

specifically targets these cells. He will beworking with the DRI’s Luca Inverardi, M.D.,Jay Skyler, M.D. and Alberto Pugliese, M.D.,and their teams to further investigate these strategies.

Re-educating the Immune System with Stem Cells

Drs. Inverardi, Skyler and Pugliese, togetherwith Mark Atkinson, Ph.D., of the University ofFlorida, are also involved in another excitingproject with Yong Zhao, Ph.D., of the Universityof Illinois/Chicago. Dr. Zhao has completed astudy in Chinese patients with type 1 diabetesof long duration and shown that recirculationof the patient’s blood cells through a machineseeded with stem cells was followed by an increase in insulin production in patients thatwere not producing any insulin before thetreatment. It is believed that exposure of thepatients’ white blood cells to the stem cellsmay re-educate the immune system and facilitate regeneration of insulin-producingcells. Dr. Inverardi, who was very interested inthe study, provided commentary for the newsstory and shared the findings with our otherDRI scientists. Dr. Zhao was invited to the DRIto present his work on the preliminary studyconducted in China. The researchers are nowexploring avenues for working together and

further developing the therapeuticefficiency of this approach.

Learning from Cancer

Vincenzo Bronte, M.D., professor ofimmunology at the University ofVerona in Italy, is a world-recognizedimmunologist who pioneered thefield of myeloid-derived suppressorcells (MDSCs), which are special immune cells found in large numbersurrounding tumors. These cells interferewith the body’s ability to detect and destroythese malignancies. He and his colleagues areinvestigating methods to eliminate MDSCs incancer patients in order to destroy the tumors.

At the DRI, Dr. Inverardi and his team areworking with Dr. Bronte to achieve the oppositeresult. They are focusing on developingstrategies aimed at increasing the number of MDSCs to protect transplanted insulin-producing cells and eliminate the need forpowerful anti-rejection drugs.

Addressing Cell Supply with Pig Islets

Long-time DRI collaborator Bernhard Hering,M.D., professor of surgery and scientific directorof the Schulze Diabetes Institute at the University of Minnesota, has been pursuingthe use of pathogen-free pigs – a special

“clean” herd of pigs – as an unlimited sourceof insulin-producing islets cells. He and histeam have conducted a series of pre-clinicaltrials using innovative immunosuppressivetherapies, which have resulted in prolongedinsulin independence in the study models.

At the DRI, several research teams have beenworking with Dr. Hering and preparing toconduct clinical (patient) transplantation trialsusing the pig islets together with the newcocktails of drugs, as well as testing the newconformal coating encapsulation methodsdeveloped and patented by our tissue engineering team (see story Under the Microscope with Chris Fraker on page 9).

11 |

AROUND

THE DRIDRI AND FOUNDATION CO-ORGANIZERS OF WORLD STEM CELL SUMMITThe Diabetes Research Institute and Foundation are serving as co-organizing partners of the8th annual World Stem Cell Summit, scheduled for December 3 – 5, 2012 at the Palm BeachConvention Center in West Palm Beach, FL. This annual Summit is the global stem cell and regenerative medicine community’s flagship event and brings together scientists, patients,advocates, business people, government representatives and more who share knowledge andtackle the field’s most important issues.

This year’s Summit will feature more than 170 renowned international speakers conductingin-depth program tracks in science, business and society, and attract more than 1,200 attendees.

DRI Scientific Director Camillo Ricordi says, “Diabetes currently affects more than 360 millionpeople worldwide and it is predicted that within the next 18 years the toll will pass the 500million mark. Stem cells are central to ongoing cure-focused strategies at the DRI and at over30 collaborating centers worldwide that comprise the DRI Federation and the Cure Alliance.”

Joining the DRI and DRIF as co-organizers is the Genetics Policy Institute, the producer of theWorld Stem Cell Summit, the Interdisciplinary Stem Cell Institute (ISCI), one of the DRI’s partnercenters at the University of Miami Miller School of Medicine, the Karolinska Institutet inStockholm, Sweden, a partner in the DRI Federation, and the City of Hope.

For more information on the World Stem Cell Summit, visit WorldStemCellSummit.com.

NEW IMMUNOSUPPRESSION REGIMEN PROMOTES LONG-TERM INSULIN INDEPENDENCE DRI Director of Clinical Islet Transplantation Dr. Rodolfo Alejandro and the clinical cell transplantteam together with collaborators Dr. Bernhard Hering and his team at the University of Minnesota have shown that long-term insulin independence can be achieved in islet transplantpatients who receive potent immunosuppression during the pre-transplant phase. The patientswho received the new immunosuppressive regimen were twice as likely to remain insulin freefor more than five years as compared to patients receiving the previously-tested drug levels.Insulin independence rates in the recipients approach those seen in pancreas transplants. Theresults of the study, which were published in the May issue of the Journal of Transplantation,suggest that this drug regimen may benefit long-term outcomes through improved engraftmentof a greater number of islets – less islets die off during initial implantation – and minimizedrecurrent autoimmunity.

Norma Kenyon NamedChief Innovation Officerat UMThe DRI’s Norma Sue Kenyon, Ph.D.,has been appointed chief innovationofficer at the University of Miami MillerSchool of Medicine. In this new role,Dr. Kenyon will lead the University-wide efforts to identify and promoteits innovative discoveries and bringthem to market to serve a widergroup of patients suffering withhealth conditions.

Her appointment comes at a time whenthe University of Miami is advancingits goal to reach the top ranks of thenation’s medical centers by becominga top 20 medical school by 2020, aswell as a medical destination for allpatients from South Florida and beyond.

Dr. Kenyon succeeds UM's Jack Lord,M.D., who recently was named chiefoperating officer of the Miller schooland UHealth. She also serves as theMartin Kleiman Professor of Surgery,Medicine, Microbiology and Immunol-ogy and Biomedical Engineering, andthe executive director of the Wallace H.Coulter Center for Translational Researchat UM. She is also a senior scientist atthe DRI.

Please join us in congratulating Dr.Kenyon on this prestigious and well-deserved appointment.

the capacity to generate oxygen when it'sexposed to water. In testing, the materialcreated an environment that sustainedoxygen supplementation for more than sixweeks – which could bridge that critical gapbetween the time islets are transplantedand the time blood vessels are formed tosupport them. Our hope is that an addedinfusion of oxygen will make Dr. Stabler’s"scaffold," a three-dimensional frameworkdesigned to promote the survival of trans-planted cells, a more viable tool for futureclinical trials.

Q. How will this body of research lead us toa cure for diabetes?A.We know that oxygen plays a critical rolein the development and function of insulin-

producing cells. By delivering oxygen moreeffectively to stem cells as they mature inthe lab, we can create an unlimited supplyof islet cells for transplantation. And, if wecan ensure transplanted cells get the oxygenthey need, especially during those criticalfirst few days, they'll have a better chanceto survive long term. Both of these need to happen if we're going to make cellulartherapy viable and available to the millionsof people who can benefit from it.

Q. Why the DRI?A. Early in my career, I was involved in moretreatment-based work: designing implantableglucose sensors with the hope of couplingthem with insulin pumps. But I knew thatwas never going to lead to a true cure. I found

the cellular-based therapy work being doneat the DRI fascinating, and I literally badgeredDr. Camillo Ricordi, the Institute's scientificdirector, or rather his executive assistant,Mabel Luis, until he hired me. That was 15years ago, and there's a simple reason I'mstill here. Everyone at the DRI and at theDRI Foundation is committed and driven tofind a cure. It's a remarkable place.

To learn more about the cure-focused research being conducted by the DRI or to view scientist profiles and published findings in peer-reviewed journals, sign up to receive our Under the Microscope e-Newsletter. Simply login or create your DRInsider profile.

Under the Microscope story continues from page 9.

Cover story continues.

Dr. Roep, pictured with the DRI’s Drs. Inverardi and Ricordi, has demonstrated that islet cells can be reactivated after a type 1 diagnosis.

13 |

Shop Cure Thrift Shop OnlineWhen even Kate Middleton, the Duchess of Cambridge, is donning thriftshop finds, the allure of thrifting cannot be denied. Vintage-over-newis all the rage, and the ultimate advantage is uncovering items thatare no longer available, which means no one can copy your personalstyle. Perhaps that’s why Elizabeth Wolff’s Cure Thrift Shop to benefitthe Diabetes Research Institute has become the go-to NYC spot forbargains, trends and unique treasures. Can’t make it to Manhattan?

Shop online at CureThriftShop.com.Liz sifts through the various donatedgoods each week to select a numberof interesting items specifically forthe online store, which is continuouslybeing updated. Affordable and easilyshipped right to your door…you can’tbeat that!

In Honor and Memory, In Lieu of GiftsGraduation parties abound, and soonwe’ll all be recognizing dear ol’ dadon Father’s Day. Rather than sendtraditional gifts or yet another tie, whynot send an e-card with a donationto the Diabetes Research Institute in honor of your loved one? It’s a wonderful way to show someone youcare and express your commitmentto a cure. The DRI Foundation makes

it simple to do. Just call 1-800-321-3437 or visitDiabetesResearch.org/ecards.

E-Giving…“E” as in Easy!Online giving continues to grow at a rapid pace. That’s because it’snever been so easy to support the cure-focused research at the DRI.Every day, donors are finding the green Donate Now button on everypage of our website (DiabetesResearch.org), and we can’t thank youenough! But why not take it a step further? Become an e-activist.Share the fact that you made an online gift on Facebook. Statisticsshow that a friend’s FB post is a more powerful motivator than a solicitation directly from the organization. If finding a cure for diabetes is one of your top priorities, get wired and watch yourwords go viral.

“Don’t Do Nothing” This SummerSummer is upon us. To most families, that means summer camp, vacation plans, beach days and much-needed relaxation. And yes,you absolutely do deserve a break! But have you thought about organizing your own fundraising project and joining other DiabetesDiplomats to support the DRI’s work toward a cure? Make summermeaningful for you and your family. Host a lemonade stand or a car wash. Create your own fundraising webpage at DiabetesResearch.org/DiabetesDiplomats, then share with your network. The possibilities are endless. Just don’t do nothing! Be theHero this summer by becoming a Diabetes Diplomat for the DRI.

If you have an idea of your own and just aren’t sure how to executeit, contact us at TomKarlya@drif.org.

There are so many different ways to contribute to the Diabetes Research Institute Foundation. Below is a short list of easy ways to give,and we have additional ideas posted on our website. Go to: DiabetesResearch.org/WaystoGive

LET ME COUNT THE WAYS TO GIVE

A FREE GUIDE TO PLANNING YOUR WILLDeveloping your estate plan and preparing a will are two of the most important things you can do to protect your family and your legacy.For a limited time, the DRI Foundation is pleased to provide you with a free Wills Kit, which contains worksheets that will make it easierto compile the required information and outline your wishes. Whether you are creating or updating your will, A Guide to Planning YourWill is designed to encourage you to think about how you want your assets to be distributed and to assist you in gathering the infor-mation for your attorney.

Contact us today – call (800) 321-3437.

LET US PAY TRIBUTE TO YOU!If you have named the DRI Foundation as a beneficiary in your will or in your estate plans (such as your retirement plan, life insurance, giftannuity or trust), you are eligible for membership in the DRI Heritage Society.

DRI Heritage Society members are recognized in perpetuity on a designated Wall of Honor at the Diabetes ResearchInstitute. Members also receive a distinctive Heritage Society award and are listed in our Annual Report.

As a token of our appreciation, new members who join the DRI Heritage Society by December 31, 2012 will receive an additional special memento. For more information, please contact Jill Shapiro Miller, vice president of gift planning, at (800) 321-3437.

SHARING DIABETESTHE YEDO FAMILY’S STORYWhen your child is diagnosed with diabetes, a thousand thoughtsstart pulsing through your mind…but there’s no family history…havewe done something to cause this…if only I could change places withmy child. Jennifer Yedo, a South Florida mother of three girls,Stephanie, Madeline and Charlotte, had all these thoughts and morewhen her eldest daughter, was diagnosed with type 1 diabetes atthe age of 4. And though she couldn’t change places with Stephanieand couldn’t take away the pain and the burden of this disease, shehas recently gained a newfound respect for all that her daughterhas had to endure over the last 13 years.

Diagnosed with diabetes earlier this year, Jen is now insulin-dependent herself.

“I had the classic symptoms, the thirst, the hunger – everything Iremember my daughter going through,” Jen said. “I checked myblood sugar, and it was 400. The doctor put me on insulin rightaway, and I was also diagnosed with celiac disease.”

Jen’s double diagnosis was a low blow for a family that had alreadybeen dealt a difficult hand. Jen also has chronic myeloid leukemia(CML). “It’s been one thing after the other for many years,” she said.Yet, the Yedo family has found a “new normal” that works for them.

“Our whole family is gluten free. My husband, Jim, was adamantabout all of us doing the same thing and adapting to what needsto be done. He is my rock, and actually I feel really fortunate,”stated Jen, who is one of the DRI Foundations’ PEP Squad leaders(Parents Empowering Parents). “But more than anything else, I feltguilty. I was getting upset that I have diabetes – that I have tocheck my blood sugar and take insulin. There are days when I justdon’t want to do it. But, my child has been doing this since she was4 years old! Who am I to feel upset?

“When I had my first low, Stephanie was right next to me talkingme through it,” recalled Jen, referring to the role reversal as surreal.

“My mom got really nervous because it was her first really lowblood sugar,” said Stephanie, who is 17 and a junior in high school.“She was overdosing on sugar, and I told her, ‘You just have to calmdown and everything will be fine. I’ve felt like that too.’”

Jen explained how her perspective has changed. “The first wordsout of my mouth were always, ‘What were your numbers today atschool?’ It drives me crazy now that Jim asks that of me! So, it’s nolonger the first thing we talk about, and I’m not as hard on her as Iused to be.

“I can’t imagine doing all of this as a teenager. They are dealingwith something that’s well beyond their years. Hopefully, otherparents can understand that from me,” Jen stated.

Stephanie, who just made the dance team at school and looks forwardto college in another year, said, “Before, we used to have littlefights when my blood sugars were out of range, but now that’sbetter because she understands.”

Stephanie is also proud that her family is so involved with the DiabetesResearch Institute. In addition to being part of the PEP Squad,they’ve sponsored and attended multiple fundraising events. “Ilove helping out because it means we’re even closer to a cure.”

DOLLARS ADD UP WITH CAESARS ENTERTAINMENT AND THE UNIONSWhen you hear the name “Caesars,” you might think of the lavish Las Vegaslifestyle, spectacular dining, unbelievable spa treatments and pool scenes fit forRoman gods and goddesses, plus extraordinary entertainment. If you add “good will”to that account, you’ll be right on the money! For each Building and ConstructionTrades Department (BCTD) convention held on a Caesars Entertainment property(which own s Harrah’s, Caesars and Horseshoe, to name a few), the company donates $1 per room night to the Diabetes Research Institute. Those dollars add upremarkably fast, and the company has donated more than $1 million for ourcure-focused work.

Caesars Entertainment National Sales Manager, Nancy Smalkas, stated, “Wecould not be prouder of our partnership with both the BCTD and the Labor of Lo ve event. We know that the research we have funded over the years at the Diabetes Research Institute, through this event, is money well spent in the

unyielding efforts to find a cure. We are here, with our Labor Partners, until the millions who suffer with this disease see the cure we all hopeto one day realize.” Nancy recently presented the latest check to new BCTD President Sean McGarvey (pictured).

A generous contribution has been made in your name to supportthe promising work of the Diabetes Research Institute (DRI).Write your message here.

HAPPY FATHER’S DAY!A Gift of Love …

A Gift of Hope

200 S. Park Road, Suite 100, Hollywood, FL 33021 (800) 321-3437 DiabetesResearch.org

Julia Gardner raised $21,000 by accepting donations to the Douglas B. Gardner Foundation in lieu ofBat Mitzvah gifts. With the support of her mom, Jennifer Gardner Trulson, Julia used that impressivesum to make her family’s foundation one of the top sponsors of Carnival for a Cure. Julia was eager tosupport the DRI in honor of two important people in her life who have type 1 diabetes – her friend,Remi Katz, and her step-father, Derek Trulson. The humanitarian teenager is shown here accepting acertificate of appreciation from WCBS-TV news anchor Chris Wragge, the event’s entertaining emcee.Julia makes it clear that age has no bearing on one’s ability to be an effective fundraiser. Will you follow in her philanthropic footsteps?

HUMANITEENEVENTS

Fall into Fashion

One of Long Island’s most anticipated events, Fall into Fashion attracted more than 400 guests to FreshMeadow Country Club in Great Neck, NY, on November 3, 2011. A colorful fashion show was presented byRED Valentino in collaboration with stylist, entrepreneur, designer and philanthropist Steven Dann. Threeaccomplished women were honored, including Frances B. Reid, director of Environmental Planning for theTown of North Hempstead, Humanitarian Wendy Waller, and Honorary Chairperson Nassau County Dis-trict Attorney Kathleen M. Rice. According to Co-chairs Fran Helfant, Korey Liebman and Roberta Waller,the event raised more than $235,000 for the DRI.

15 |

Effectively warding off the cabin fever thatlingers in early spring, nearly 1,000 New YorkTri-state area residents of all ages jumpedat the chance to get out of the house andinto a party on two different weekends ofMarch. While focusing on fun, they helpedraise nearly $400,000 for the DRI.

“Our goal has always been to get people involved and engage them in the fight to finda cure,” said Frankie Lam, who co-chaired KidsParty for a Cure along with René Checchia.“The Kids Party does that by combining funand a very important message of hope andsupport for diabetes research.”

At the Ninth Annual Kids Party for a Cure children and adults alike were busy fromthe moment they entered Dave and Buster’sat the Mall at The Source in Westbury.While some were mesmerized by endlessvideo and arcade games, others enjoyedjumping on inflatables, sharpening theirpool skills or bowling. Food and prizes werea hit, but the highlight of the afternoon formany was the opportunity to meet 17-year-old actor Jake T. Austin, who is best known

for starring in Disney’s award-winning series,“Wizards of Waverly Place” alongside SelenaGomez. Guests of all ages were charmed byJake as he chatted with fans, signed every-thing from cell phones to teddy bears, andeven made a donation to the DRI!

“We couldn't be happier with our specialguest,” René said. “He is a wonderful and giving young man. His compassion for children with type 1 diabetes and to finding a cure is to be commended.”

In New York City at the Metropolitan Pavilion,the Seventh Annual Carnival for a Cure alsooffered family-friendly fun. Led by Sabrinaand Scott Chosed and Meredith and ScottBuchwald, the hard-working Carnival committee was proud to give kids andadults alike a spectacular Sunday afternoonfilled with tasty foods, thrilling games, magic,crafts and prizes galore.

“I’ll do anything to find a cure for mydaughter, and this event allows the kids tofeel like they’re part of finding the curetoo,” commented Meredith.

As their children raced from one activity to the next, parents and grandparentsshopped the silent auction, which featuredseveral exclusive offerings such as a chanceto have “Elmo” from Sesame Street leave apersonalized voicemail, tickets to Broadwayshows, Pinkalicious-branded items, high-end hotel stays, sports packages, jewelryand more.

Activities came to a standstill when NewYork’s WCBS-TV News anchor Chris Wragge,took the stage to introduce teen singingsensation, Jenna Rose. Flanked by back-updancers, she performed two lively choreo-graphed songs.

Thanks to the generosity and participation of so many, Kids Party and Carnival producedmuch-needed funds for the DRI, while creating a fun-filled afternoon for familymembers of every generation.

No matter what your age or the place youlive, you can get involved too! Don’t miss out on a thing. Like us on Facebook atwww.Facebook.com/DiabetesResearch.org.

Reflecting the burgeoning partnership between Walgreens and theDRI Foundation, the second Walk with Walgreens Family Fun Day andHealth Fair, presented by LifeScan and Neutrogena SunCare, morethan doubled the proceeds of its premier event! Held simultaneouslyin four South Florida locations on March 24, the family affair attractedthousands of walkers, including dozens of members of the DRI’sfaculty and staff, to Central Broward Regional Park in Fort Lauderdale,Tradition Square in Port St. Lucie, Amelia Earhart Park in Miami, andOkeeheelee Park in West Palm Beach.

In Fort Lauderdale, singer/songwriter Crystal Bowersox gave anacoustic performance, which was presented by LifeScan, Inc., makersof the OneTouch® Brand of blood glucose monitoring systems. Diagnosed with type 1 diabetes two decades ago, she was a seasonnine American Idol finalist and has used her rising star status toencourage others with diabetes to live their dreams.

Other VIPs participating in the special day included: former NewYork Mets pitcher and DRI Foundation board member Ron Darling;Walgreens Market Vice President Roy Ripak; LifeScan National AccountDirector Vince DeTurris; Diabetes Research Institute Scientific DirectorCamillo Ricordi; Walgreens Market Pharmacy Director GeorgiaLehoczky; former Miami Dolphins players John Offerdahl and NatMoore; Mayor Richard J. Kaplan of Lauderhill; Mayor JoAnn Faiella ofPort St. Lucie; and teen pop singer Meghan Ritmiller. Also deservingspecial thanks are Walgreens Site Coordinators Steve Flynn, Dan Espinosa, Tim Martinez, Anthony Contento, Mariela Tuero and TomLehoczky, as well as Family Team Chair Rita Hart.

The top fundraisers of the day were: Team Jace, The Tacher Family;Team Colby, The Ferris Family; Team Brother Sister, The GreenwaldFamily; Team Sammy, The Schechter Family; and Team Jax, led byLisa Grace and family.

at Kids Party for a Cure & Carnival for a CureMISSION: ENGAGE EVERY AGE...ACCOMPLISHED

1. Carnival for a Cure Chairpersons Scott and MeredithBuchwald and Sabrina and Scott Chosed

2. DRIF Long Island Regional Chairman Allan L. Pashcowwith Jake T. Austin and Kids Party for a Cure ChairpersonsRené Checchia and Frankie Lam

1 2

WALK WITH WALGREENS FAMILY FUN DAY & HEALTH FAIRS OFFERHEALTH, HOPE & HARMONY

1. Walgreens Market VP Roy Ripak with his daughter, Samantha, LifeScan National Account Director Vince DeTurris, Crystal Bowersox, and DRI Foundation VP Tom Karlya. 2. Team Jace, led by Jenn and Jared Tacher, raised more than $7,700 and was comprised of 60 friends and family members of 4-year-old Jace. 3. Ron Darling speaks of hishope for a cure as Port St. Lucie Walgreens Site Coordinator Steve Flynn, Family Team Chair Rita Hart, and DRI Foundation COO Debora Chodrow look on. 4. DRI ScientificDirector Camillo Ricordi, MD, who participated with several other members of DRI faculty and staff, is pictured with Walgreens Market Pharmacy Director GeorgiaLehoczky. 5. Colby, Sabrina and Sage Ferris of Team Colby, which raised nearly $6,500 in honor of Colby. 6. Raising more than $5,500 was Team BS (Brother Sister), organized by Jonny Greenwald, far right, in honor of his sister, Lexi, 3rd from left.

1 2 3 4 5 6

17 |

At the Empire Ball, the signature event of the DRI Foundation’s Real Estate Division, Chairman Peter L. DiCapua and Special Guest Ron Darling kicked off the organization’s first-ever “Text to Pledge” campaign. Attendees responded withenthusiasm, adding nearly $40,000 to the amount raised and bringing the totalto nearly $1 million. Three distinguished notables of the industry were singledout, including Camillo Ricordi Humanitarian Award recipient Michael Rodriguez,Leadership Award recipient William (Billy) Macklowe, and Distinguished ServiceAward recipient Richard A. Laskowski, who are pictured (l-r) with Darling (secondfrom left.) More than 750 guests were in attendance at the elegant affair, whichwas held on December 14 at the Grand Hyatt Hotel in New York City.

Empire Ball

Holiday music and candlelight set the mood for the DRIF’s annual Long Island regional holiday celebration on December 15 at the Muttontown Club in East Norwich, NY. Attendees sampled delectable cuisine as many special guests were recognized for their dedication to the DRI. The holidayreception was graciously hosted by Roberta and Bruce Waller, and awards were presented to Gigi andMichael Otten, Addy Fritzhand, Wendy Waller, Iris and David Feldman, and Allan and Louise Pashcow,among others. Pictured are Roberta and her daughter, Dara Melnick.

EVENTSLI Holiday ReceptionPleasures of the Palate

In South Florida, Miami’s recently revamped restaurant, The Forge, played host to the 13th Annual Pleasures of the Palate dinner on November 11. Known for its dramatic wine cellarsand innovative fare, it was the perfect setting for a crowd of foodies and wine enthusiaststo enjoy a four-course dinner paired with wines. According to Chairpersons Tammy andSteven Klein, shown with their daughter and son, Carly and David, the affair attracted 140guests and raised more than $80,000 for the DRI.

All In for a Cure

The fourth annual All In for a Cure Texas Hold ‘em poker tournament tookplace on the evening of November 8 at The Grand Havana Room in midtownManhattan, NY. More than 200 guests enjoyed fine wines, spirits and cigars,while taking in breathtaking views of the city and playing spirited handsof poker. Thanks to the dedication of the co-chairs (pictured l-r) JordanDickstein, Samantha Shanken Baker, Troy Gregory, Greg Rosenberg, Ricardo Salmon and Isaac Khafif, the event raised in excess of $300,000,moving cumulative proceeds above the $1 million mark! Among theguests were famed sports personalities Carl Banks and Ron Darling. NeilRock clinched the winner’s cup, while Dr. Stephen Silver took second place.

Love and Hope Preview Party

Commencing their 38th season, the fabulous ladies of Love and Hope raised morethan $600,000 at the Love and Hope Preview Party on November 17. Life ChairmanSonja Zuckerman welcomed nearly 200 guests to the Diplomat Country Club in Hallandale, FL, and extended heartfelt thanks to Isabel May for underwriting themagnificent evening for the ninth consecutive year. Executive Chairman Sandra Levyannounced that International Chairman Barry Gibb would provide a private concert at the 38th Annual Love and Hope Ball. Sabrina Ferris also stood before theguests with her son, Colby, to express their appreciation for the group’s efforts inraising money toward a cure for him and everyone else living with type 1 diabetes.May is pictured (center) with Neiman Marcus Bal Harbour GM Frances Esquenaziand models displaying jewelry from the store.

Champions for Charity

Kicking off the holiday season for DRIF supporters on Long Island, Americana Manhasset’s Donna Karan New York store hosted a livelycocktail reception on December 1, where Hal Rubenstein, the charmingfashion editor, presented his favorite dresses from the Donna Karan resortcollection. Rubenstein was on hand throughout the reception to autograph copies of his new book, 100 Unforgettable Dresses. Duringthe first three days of the month, 25 percent of all purchases made witha Champions for Charity Card at participating Americana Manhassetand Wheatley Plaza stores were donated to the DRI when it was selected as the cardholder's organization of choice. Pictured withRubenstein (center) are (l-r) Co-chairs Korey Liebman, Eileen Zinn andFran Helfant, plus Americana Manhasset President Diedre Costa-Majorand DRI Foundation COO Deborah Chodrow.

Held at the Westin Diplomat Resort & Spa in Hollywood, the 38th Annual Love and Hope Ball was truly A Family Affair for International Chairmen Barry and Linda Gibb and 600 others in attendance. While honorees shared the spotlight with their children and grandchildren, themusic legend shared the stage during an extraordinary, full length concert with his son, Stephen Gibb, and his niece, Samantha Gibb. According to Life Chairman Sonja Zuckerman and Executive Chairman Sandra Levy, the spectacular gala, combined with November’s PreviewParty, raised $1 million. During the dinner program, Mistress of Ceremonies Lisa Petrillo recognized the evening’s honorees: Grand HumanitarianShirley Harris; Humanitarian Honorees Sheila Wohl and Family; Honorary Chairman Isabel May; Love Honorees Tova Leidesdorf and Family; andHope Honorees Senator Paul and Sandy Steinberg. She also gave thanks to the sponsors: The GEO Group; Saks Fifth Avenue Bal Harbour;Neiman Marcus Bal Harbour; Gold Coast magazine; and Norwegian Cruise Lines. Apropos of the evening’s theme, one other family was honored, the Love and Hope Family (pictured), many members of which have been working on the committee for 38 years.

Love and Hope Ball

American Fine Wine Competition Gala

Sportsmen for Charity

19 |

Benefiting the DRI for the tenth year, the Sportsmen for Charity sporting clay fundraiser was held onFriday, April 20 at the Pawling Mountain Club in Pawling, NY. The club, bordered by a 1500-acre expanse,features panoramic views of the Appalachian Trail National Park.  Chaired, as always, by Charles Guigno,the sold-out event started with a hearty breakfast and practice rounds. It continued with a friendlycompetition among sportsmen, followed by a cocktail reception in the main lodge, where guests enjoyeddessert, coffee, wine, cheese, cigars and awards. Pictured with Charlie Guigno (far right) are DRI Foundation

Long Island Regional Director Tony Childs, Phil DeLorenzo, and Charlie’s grandson, Joseph Ferrigno.

While people all over the world were going green on Earth Day, friends of the DRI inBoca Raton, FL, were raising ‘green’ on the green! According to Jeannie and Ken Fibus,chairpersons and presenting sponsors, the event’s proceeds surpassed $120,000. Namedfor their daughter, the Randi Fibus-Caster Pro Am Diabetes Golf Classic provided the opportunity for amateur golfers to play alongside pros. It also featured a cocktail reception and dinner, where two children with type 1 diabetes, Brooke Miller, 13, and JoshEspinosa, 8, thanked the 200 guests in attendance for helping the DRI move closer to acure. Randi Fibus-Caster, the event’s namesake, said, “In the past decade I’ve received

two islet cell transplants at the Diabetes Research Institute, and now I take no insulin. I am living proof of the science and research taking placethere.” Randi is pictured with her husband, Ron Caster (l) and her parents (r).

Randi Fibus-Caster Pro Am Diabetes Golf Classic

EVENTS

The DRI was thrilled to benefit for the second year from the auctions and raffles of the AmericanFine Wine Competition Gala, the brainchild of Shari Gherman and Sara and Monty Preiser. Thisyear, the trio “kicked it up a notch” with the participation of Celebrity Chef Emeril Lagasse, whoprepared the evening’s main course on stage. A lottery was held to determine which lucky eightattendees would be seated on stage with Emeril. The extensive silent auction offered wine baskets from boutique style wineries across the nation, as well as exotic vacation packages and

more. Presided over by Alan Kalter of the Late Show with David Letterman, the live auction featured such items as a dream dinner preparedby renowned chefs in the area. World famous Saxophone player Dayve Stewart & the Vibe entertained, and close to $65,000 was raised forthe DRI during this unforgettable evening presented by Patriot National Insurance Group. Pictured with DRIF’s Robert Pearlman are (l-r)Gherman, Kalter and Lagasse.

Cooking for a Cure

Now in its ninth year, Cooking for a Cure was held on April 2 at PageOne Restaurant in Glen Cove, NY. Celebrated Chef Jeanine Dimennaonce again prepared a gourmet dinner for the guests in attendance.Chaired by Delia DeRiggi-Whitton, who is a Nassau County Legislatorand a DRIF board member, the event honored Jeannie and GregTrunz of The Swan Club and Special Guest Glen Cove City CouncilmanAnthony Jimenez. Long Island’s own Kevin Covais, American Idol

season five finalist, provided special entertainment. Pictured (l-r) are: Glen Cove Mayor Ralph Suozzi, Covais, DeRiggi-Whitton, Ellen McCormack, Jeannie and Greg Trunz, Anthony Jimenez and Kathy Jimenez.

A Gift of Love… A Gift of Hope

Fitting for the elegant ladies of the Palm Beach Auxiliary, the luxurious Polo Club of Boca Raton played hostto the 13th annual A Gift of Love…A Gift of Hope event on February 27 in Boca Raton, FL. The sold-out affair,featuring a luncheon, shopping boutique and card party, raised more than $55,000. While enjoying a deliciouslunch, 220 guests heard from Randi Fibus-Caster, who has lived with type 1 diabetes for 50 years, as well asher mother, Jeanne Fibus. Pictured are DRIF COO Deborah Chodrow and Renee Aronin, event chairperson.Since its inception in 1998, the Palm Beach Auxiliary has raised nearly $500,000 for the DRI. Anyone wholives in Palm Beach County and is interested in joining should call the DRI Foundation at 800-321-3437.

New England Patriots nose tackle Vince Wilfork and his wife, Bianca, (bothpictured center) welcomed 900 fans to Pinz in Milford, MA, on April 26 fortheir annual Draft Day Fundraiser. The sold-out affair featured autograph-signing sessions and photo opportunities with Wilfork and several of histeammates, including Kevin Faulk, Jerod Mayo, Ron Brace, Patrick Chung,Gerard Warren, Kyle Love, Ras-I Dowling, Devin McCourty, Sterling Moore,Ryan Mallet, Zoltan Mesko, Matthew Slater and Sergio Brown. The event,which was emceed by Boston Channel 5 news anchor Bianca de la Garza,also offered unlimited bowling, food and the perfect ambience for watching

the NFL draft. Thanks to title sponsor EMD Millipore and the generosity of many others, the event raised $200,000. Though Wilfork has beenfundraising for the cause ever since his father passed away from complications of diabetes a decade ago, he called this “the best year yet.”

Vince Wilfork’s Draft Day Fundraiser

Shell Key West Fishing Challenge

Now in its 14th year, The Crystal Ball was held on April 28 at The Garden City Hotel in GardenCity, NY. John C. Doscas (center) served as Crystal Ball Honoree, while Nicholas H. Racanelli(left) received The Gillin Family Humanitarian Award and Charles Rizzo (right) received theDistinguished Service Award. Each of these three gentlemen spoke passionately about thecause, sharing with the 325 people in attendance how diabetes has personally touched theirlives. According to Co-chairs Bruce Waller, Michael Genatt and Allan L. Pashcow, $640,000was raised for the DRI.

The Crystal Ball

The Shell Key West Fishing Challenge was created 24 years ago by Jo and HaydenBlaylock, founder and CEO of Blaylock Oil Company. The event started benefiting theDRI after their grandson, Matthew Sanchez, was diagnosed with type 1 diabetes andhas now raised close to $500,000 toward a cure. Just as they have the past six years,DRI representatives, including Dr. Luca Inverardi, joined hundreds of Shell executives,employees, wholesalers and corporate sponsors April 26-29 on the gorgeous waterssurrounding Key West for a deep sea fishing competition. Thanks to the leadership ofCrystal Blaylock, Matthew’s mother and the event coordinator, the long weekend en-deavor was as big of a success as ever.

Spin For a Cure

On April 22, the first annual Jake, Jesse and Ally Rosenberg “Spin For A Cure” took place at the Maxfit studioin Cresskill, NJ. The entire Rosenberg clan, including mom Denise and dad Greg, cycled with 50 friendsin two 55-minute sessions, led by instructor Jennifer Sherman. The idea for this event came straightfrom the Rosenberg children. (Greg co-chairs the Northeast region’s All in for a Cure poker event.) Onthe Spin for a Cure invitation, Jake, Jesse, and Ally had this to say about diabetes, “…this terrible disease has changed the lives of our family. The DRI is our best hope for a cure.” Thank you to

the Rosenberg family for getting the word out and raising funds in honor of Jake (14), who was diagnosed with type 1 diabetes a year ago. Pictured (l-r) are Greg Rosenberg, Jake Rosenberg, Ally Rosenberg, Denise Rosenberg, Jennifer Sherman and Jesse Rosenberg.

CALENDARBuy In for a Cure June 14, 2012 / LONG ISLANDThis Texas Hold'em Tournament willbe held at The Garden City Hoteland feature an evening of games,prizes, sweepstakes, food, wine andspirits.

Mastering Your Diabetes June-August-October 2012 / FLORIDAThis 5-day intensive course is specifically for patients who injectinsulin. June classes, from the 18th-22nd are geared for the under 18 crowd, while the August 23rd-27thand October 18th-22nd classes are foradults. Five classes offered every year.For more information, call ArleenBarreiros at 305-243-3696.

Ron Darling Celebrity Golf Classic July 9, 2012 / LONG ISLANDDRIF National Board member andformer Major League pitcher RonDarling hosts this afternoon of golf followed by cocktails and anawards dinner, to be held at the PineHollow Country Club.

Rod Gilbert DRI Golf ClassicAugust 6, 2012 / LONG ISLANDTo be held at Pine Hollow CountryClub, this event will honor Sam Barrettaand feature an afternoon of golf followed by an awards dinner and asilent auction. It is co-chaired by EricReeps and Bob Zuckerman.

Gold Coast Concours / Bimmerstock September 9, 2012 / LONG ISLANDHundreds of exotic cars and BMWswill be showcased throughout theday at this magnificent exhibit, to be held at the City of Glen Cove’sdowntown business district and presented by Martino Auto Concepts/ MAC Auto Coutureof Glen Cove. Join us from 11 a.m. to 4 p.m., rain or shine.

Phil Peterson’s Key West Poker RunSeptember 13–16, 2012 / FLORIDAPhil Peterson will host his 40th annual motorcycle run, which startsin Miami and finishes in Key West forSouth Florida’s biggest biker partyweekend of the year. Participantscan make stops along the way to

purchase poker hands in hopes of winning a new Harley!

Brindisi Coalition for the Cure September 15, 2012 / NEW YORKAttorney Louis Brindisi will hold his second event at The Fort SchylerClub in Utica in honor of his son,Louis Thomas Brindisi, 14, who was diagnosed with type 1 at age 11.

The Donaldson Organization Golf Outing October 1, 2012 / NEW YORKThe Donaldson Organization willhost a golf outing at a private golfclub in Westchester County, NY. A full day of golf will be followed by a cocktail reception and dinner.

Fall Into Fashion November 1, 2012 / LONG ISLANDThe annual luncheon, to be held atthe beautiful Fresh Meadow CountryClub at 11 a.m., will feature a runwayfashion show, presented by Oscar dela Renta. Chaired by Barbara Hatz,the event will have fabulous one-of-a-kind auction items on display.

All in for a CureNovember 13, 2012 / NEW YORKTo be held at the Grand HavanaRoom, the fifth annual TexasHold’em tournament for poker enthusiasts will feature vintagewines, fine cigars, hors d’oeuvres and panoramic views of New York City.

Empire Ball December 12, 2012 / NEW YORKThis annual black-tie event at theGrand Hyatt Hotel is the social eventof the season for New York City’s realestate industry.

For information on the events or to make reservations, visitDiabetesResearch.org or call one of the DRI Foundation officeslisted below.

Diabetes Research Institute Foundation National Office200 South Park RoadSuite 100Hollywood, FL 33021

address service requested

Non-Profit Org.US Postage

PAIDDiabetes Research

Institute Foundation

DRIfocus

DRIfocus

The Diabetes Research Institute Foundation supports the Diabetes Research Institute at the University of Miami Leonard M. MillerSchool of Medicine, whose mission is to develop and rapidly apply the most promising research to treat and cure those now livingwith diabetes. To obtain additional information or request copies of DRIfocus, please call (800) 321-3437 or e-mail lweintraub@drif.org, or visit DiabetesResearch.org.

Marketing & Communications Dept.Lori Weintraub, APRLauren SchreierNatasha NorrisLaurie Cummings

ContributorsGary KleimanJill SalterAimee Siegel-HarrisMitra Zehtab, M.D.Stacy Zolotin

is a publication of the Diabetes Research Institute Foundation.Spring 2012 / Volume 39 / Issue 2

National Office200 South Park Road, Suite 100 Hollywood, FL 33021 Phone: (954) 964-4040 Fax: (954) 964-7036 info@drif.org

Northeast Regional Office381 Park Avenue South, Suite 1118New York, NY 10016 Phone: (212) 888-2217 Fax: (212) 888-2219neregion@drif.org

Long Island Regional Office410 Jericho Turnpike, Suite 201Jericho, NY 11753Phone: (516) 822-1700 Fax: (516) 822-3570 liregion@drif.org

DIABETES RESEARCH INSTITUTE FOUNDATION

PhotographyPatty DanielsDRIF volunteersMarc S. Levine Joe Marzo Sarah Merians Photography and Video CompanyAndrew MilneTom SteppClaude Zick

DesignFranz Franc Design Group Inc.