Download - Drug Agency Regulatory Warnings
-
7/30/2019 Drug Agency Regulatory Warnings
1/6
Drug Agency Regulatory Warnings: There have been 31 drug regulatory agency warnings
issued from eight countries on ADHD drugs causing:
Aggression
Agitation
Anxiety
Convulsions
Depression Disturbed sleep
Drug addiction/abuse
Hallucinations
Heart attack
Heart problems
Hostility
Mania/psychosis
Seizures
Stroke
Sudden death
Suicidal ideation/behavior
Violence Weight changes
Drug Studies: There have been 20 studies published from four countries on ADHD drugs
causing:
Abnormal heart rate/rhythm
Birth defects
Blood pressure changes
Delinquency risk
Depression
Drug abuse/addiction
Emotional outbursts
Hallucinations Heart problems
Homicidal ideation
Insomnia
Irritability
Mania/psychosis
Low academic performance
Stunted growth
Sudden death
Suicide risk
Violence
Weight changes
Documented Side Effects of ADHD Drugs:
Aggression/hostility
Agitation
Blood pressure changes
Changes in vision or blurred visionDepression
Dizziness or faintness
Fever
-
7/30/2019 Drug Agency Regulatory Warnings
2/6
Hallucinations
Heart attack
HivesHypersensitivity
Impotence
Increased irritability
InsomniaInvoluntary tics/twitching
Irregular heartbeat
Liver problemsLoss of appetite
Mania
Mental/mood changes
Muscle/joint tightness
Nausea
Nervousness
Painful menstruation
Psychosis
RestlessnessSeizures
Sexual dysfunction
Slow/difficult speech
Stomach pain
Stroke
Stunted growthSudden death
Suicidal thoughts
Swelling of face or throat
Tourettes Syndrome
Toxic psychosis
Unusual bleeding/bruisingUnusual sadness/crying
Violent behaviorVomiting
Weight loss
Zombie demeanor
Note: Side effects of psychiatric drugs can persist for months, if not years, after
stopping them. (1)
ADHD Drug Side Effects Reported to the FDA: There have been 14,158 Adverse Drug
Reactions in connection with ADHD drugs/stimulants that have been reported to the FDAsAdverse Event Reporting System (MedWatch), between 2004 and 2011.
The FDA estimates that less than 1% of all serious events are ever reported to it, so the actual
number of side effects occurring are most certainly higher.
-
7/30/2019 Drug Agency Regulatory Warnings
3/6
These include:
871 cases of suicidal ideation/behavior (completed suicides and suicide attempts)
636 cases of aggression
593 cases of hallucinations
499 cases of anxiety
495 cases of abnormal behavior
464 cases of depression
220 cases of death/sudden death
147 cases of mania
113 cases of withdrawal symptoms
52 cases of homicidal ideation
44 cases of diabetes
30 cases of hostility
25 cases of coma
23 cases of physical Assault
21 cases of birth defects
13 cases of violence-related symptoms
12 cases of psychosis
11 cases of homicide
9 cases of sexual dysfunction
(2)
ADHD Drug Warnings:
There have been 31 warnings from eight countries (United States, United Kingdom, Canada,
Japan, Australia, New Zealand, France and Singapore) warning that ADHD drugs/stimulants
cause harmful side effects. These include the following (note that some warnings cite more
than one side effect, so the list below may not be equal to the total number of warnings):
http://www.cchrint.org/psychdrugdangers/medwatch_psych_drug_adverse_reactions.php?g=1&advanced=false&dn=dc:Stimulant&arg=&arl=&aru=&mf=&advanced=0&search_generic=Stimulant%20(Drug%20Class)&link=true -
7/30/2019 Drug Agency Regulatory Warnings
4/6
12 warnings on stimulants causing heart problems
8 warnings on stimulants causing mania/psychosis
8 warnings on stimulants causing death
3 warnings on stimulants causing hallucinations
2 warnings on stimulants causing depression
2 warnings on stimulants causing violence, hostility or aggression
2 warnings on stimulants causing seizures 1 warning on stimulants causing suicide risk/attempts
1 warning on stimulants causing anxiety
ADHD Drug Studies:
There are 20 studies from four countries (United States, Australia, Denmark and Italy) showing
that ADHD drugs/stimulants cause harmful side effects. These include the following (note that
some studies cite more than one side effect, so the list below may not be equal to the total
number of studies):
5 studies on stimulants causing medication abuse
3 studies on stimulants causing heart problems
2 studies on stimulants causing death 1 study on stimulants causing suicide risk/attempts
1 study on stimulants causing birth defects
1 study on stimulants causing violence
1 study on stimulants causing homicidal ideation
1 study on stimulants causing depression
1 study on stimulants causing mania, psychosis and hallucinations
(1) Psychiatric Drug Side Effects Can Persist After
Stopping Them
Below are studies showing that, even after stopping certain psychiatric drugs, the side effects
may last several months to years afterwards.
Psychotherapy and Psychosomatics Journalpublished a study in October 2012 about
persistent withdrawal effects six months after cessation of taking SSRI antidepressants.
Researchers reviewed self-reporting adverse events between February 2010 andSeptember 2010 and found post-withdrawal symptoms may last several months to
years. Reported symptoms included disturbed mood, emotional liability, irritability, and
poor stress tolerance.
We note in table 1, persistent postwithdrawal disorders, which occur after 6 weeks of drug
withdrawal, rarely disappear spontaneously, and are sufficiently severe and disabling to havepatients returned to previous drug treatment. When their drug treatment is not
restarted,postwithdrawal disorders may last several months to years. Significant
persistent postwithdrawal emergent symptoms noted consist of anxiety disorders, includinggeneralized anxiety and panic attacks, tardive [developing slowly] insomnia, and depressive
disorders including major depression and bipolar illness. Anxiety, disturbed mood, depression,
mood swings, emotional liability, persistent insomnia, irritability, poor stress tolerance, impaired
concentration and impaired memory are the more frequent postwithdrawal symptoms reported
online.
-
7/30/2019 Drug Agency Regulatory Warnings
5/6
Dr. John Zajecka reported in the Journal of Clinical Psychiatrythat the agitation and
irritability experienced by patients withdrawing from one SSRI antidepressant could cause
aggressiveness and suicidal impulsivity. The study stated that, Symp toms of[antidepressant] discontinuation have been reported to last as long as 1 month.
(2) The U.S. Drug Enforcement Administration classified the stimulant methylphenidate, also known asRitalin, in the same category as cocaine, morphine and opium.
These graphs show psychiatric drug side effects that have been reported to the FDA. Scroll down to view furthedetails such as STUDIES and WARNINGS for the returned drug(s).
-
7/30/2019 Drug Agency Regulatory Warnings
6/6
(3)