oxford university press - oxford academic

Official Publication of the European Dialysis and Transplant Association - European Renal Association I

Volume 8 Number 1 1993

Appreciation Wolfgang Thoenea (Mainz), 19291 992

Editorial Alex M. Davison, Editor-in-Chief

Editorial Review Tho role of complement in mosan~ial cell damage G. M. Hamh

Editorial Comment Tho effect o f armed conflict on dialy is patients J. S. Cameron

Original Articles The impact of Iraqi occupation on and-stage renal disene potients i n Kuwait, 19961991 K. El-Reshaid, K. V. Johny, M. Georgous, M. R. N. Nampoory and N. Al Hilal

Renal d i m associated w i th HIV infection: a mukicontric study of 60 potients from Paris hospitals D. Nochy, D. Glotz, P. Dosquet, A. Pruna, C. Guettier, L. Wiss, N. Hinglais, J.-M. Idatte, J. P. M&y, M. Kazatchkine, P. Druet and J. Bari6ty

Hypmrtemion in adults w i th idiopathic glonwrulonephritis and normal serum croatinine. A raport from the MRC G l o ~ u l o n o p h r i t ~ Rwistry P. A. Johnston and A. M. Davison

Elwation o f IgA i n IgA nophropathy m localized in tho -rum and not soliva and is rostrictad t o the IgAl s u b d m L. Layward, A. C. Allen, J. M. Hattenky, S. J. Harper and J. Faohally

Antinatriurotlc action o f insulin is -ed after a n g i o t d n I converting enzyme inhibition in normal man D. W. Eadington, D. A. Hapburn and C. P. Swainson

Urinary dopamina raponso t o ongiotonsin II h not abnormal in typo 1 (insulin-d.p.nd.nt) diabetw nwllitus D. W. Eadington, C. P. Swainson, B. M. Frier, N. Johnston, R. R. ! j a m and M. R. Lbb

Nan-invwhn conductivity methad for ktoction of dynamk body fluid changu: in vitm and in v i m volM.tion C. G. Okhof, P. M. J. M. & Vries, P. M. Kouw, P. L 00, H. Sct~nsida, J. J. de Lsnge and A. J. M. Donkm

Bi.ooomp.tibility of a new high-p~nnoebil i ty modifid dluk.. m a n & 8 ~ for h.modidysk R. A Wad, R. M. !kbdw, D. Fdk.nhrrgen, M. S. Joshua, A. Heidland, H. Klinkmann and H. J. Gurland 47

Now minimato cornpodtion in high UF hwmodiafiltration: doctrotvto sdut ion c o m b i d with b h r b m t o M. G d b , G. Calabrem, G. Pratesi, C. Baldin, A. Mazzotta and G. Vsgdli

Hnmodi.lWs rdrcul.tion dotocted by the threo- rmpk method h an artd~ct J. E. TmarrN. K. Farrington, P. D. Raniga. H. Thompson, C. Todinson, C. Aldrk&p, end R. N. Grsanwood 60

Clinical d u d i o c r o f the p o r i t o m l oquilibrotion tat: a popuktbn-band study S. J. Davisr, 8. Brawn, J. Bryan and G. I. Rurrdl

Sorum l ipoprotdn (a) conantrationr in p.tionts undugdng eontinuom ambulatory pd tonoo l d i . W N. Anwar, D. Bhamrgw, C. D. Shoa M. I. Macknert, P. N. Durrington, H. Pram and R. Gokal

Local production of intorl.ukin-6 during .cute rejection in human r o ~ l a l l og r sh M.H.M.R.rwkl,J.J.Hk.ning,J.M.Ksnt. S. Surachno and R. J. M. tan Bags

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© European Dialysis and Transplant Association-European RenalAssociation, 1993.All rights reserved; no part of this publication may be reproduced,stored in a retrieval system, or transmitted in any form or by anymeans, electronic, mechanical, photocopying, recording, or otherwise,without either the prior written permission of the Publishers, or alicense permitting restricted copying issued in the UK by the CopyrightLicensing Agency Ltd, 90 Tottenham Court Road, London W1P9HEor, in the USA, by the Copyright Clearance Center, 27 Congress Street,Salem, MA 01970.

Nephrology Dialysis Transplantation is published monthly by OxfordUniversity Press. Subscription is $375 per year. Second Class paid atNewark, New Jersey. ISSN 0931-0509.

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Can you afford to be without the mostcomprehensive clinical reference?

Oxford Textbook ofClinical NephrologyK th

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ENAL SPECIALISTS all over the world have already establishedthe Oxford Textbook of CImical Nephrology as the definitive

ference in clinical nephrology.

The Oxford Textbook of Clinical Nephrology is edited by five leadingEuropean authorities and contains outstanding contributions frominternationally renowned experts in the field. Each has drawn on avast experience of clinical practice to produce a comprehensiveguide to every aspect of renal disease.

Throughout the three volumes emphasis is placed on the clinicalaspects of nephrology and ultimately the needs of the renal patient.The text adopts an integrated approach to renal disease,incorporating the important contributions to the subject from otherspecialities such as immunology, genetics, and molecular biology.Full coverage is given to the biological basis of the latest diagnosticand therapeutic tools.

The Oxford Textbook of Clinical Nephrology also contains some uniquefeatures. It deals with many of the rarer renal problems and renalmanifestations of systemic disease that are not dealt with in othertexts - as a glance at the index will show. Paediatric nephrologyhas been blended into the text throughout and several chapters dealwith the special problems faced by the growing number of elderlypatients with renal disease. The authors have taken a globalapproach and take care to highlight the different problems causedby renal disease in the tropics. Special attention is paid to thehandling of drugs by the kidney and the effects of drugs on thekidney and renal tract. The final section provides a unique guide toclinical nephrology for other specialist physicians such asgastroenterologists. rheumatologists. and neurologists.

To order your copy contact your local bookseller or OUP DistributionServices, Saxon Way West, Corby, Northants NN18 9ES Tel 0536744964 (24 hour credit card hotline) or Fax 0536 746337 (add£2.75 for P&P). When using the credit card hotline please haveready the name of the author of the book and the title, your nameand address (this should be the address that your credit cardstatement is sent to), and your credit card number and expiry date.

EDITORSJ. Stewart Cameron, Professorof Renal Medicine, Guy's Hospital,LondonAlex M. Davison, ConsultantRenal Physician, St James'sUniversity Hospital, LeedsJean-Pierre Grunfeld, Professorof Nephrology, Hospital Necker,Paris, FranceDavid N. S. Kerr, Professor ofRenal Medicine, Royal PostgraduateMedical School LondonEberhard Ritz, Head of Divisionof Nephrology, University ofHeidelberg. Germany

ASSOCIATE EDITORSA. Rees, Consultant Physician,Hammersmith Hospital, LondonC. Winearls, ConsultantNephrologist. Churchill Hospital,OxfordL. Hernando, Professor. Servicode Nephrologia, University ofMadrid, SpainC. van Ypersele, Professor ofMedicine, University of IjouvainMedical School. BelgiumC. Ponticelli, Director. Division ofNephrology and Dialysis. OspedaleMaggiore. Milan, Italy

THREE VOLUME SETAll volumes 27.5 x 22 cm withline and halftone illustrationsthroughout. Full colour platesection.Published March 1992 £2750-19-262093-2, 2500 pages

O X F O R D U N I V E R S I T Y P R E S S

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NE W FROM OXFORD

Mycotoxins, Nephropathyand Urinary Tract Tumours

Edited by M. Castegnaro, R. Plestina, G. Dirheimer,I. Chernozemsky, and H. Bartsch

This volume contains the Proceedings of an international meeting on"Mycotoxins, Endemic Nephropathy and Urinary Tract Tumours" held at

I ARC, Lyon. The 49 articles reflect current interest in the role of mycotoxins(known to be nephrotoxic to several animal species) in human diseases such asendemic nephropathy and urinary tract tumours prevalent in the Balkans and

other countries. The aetiology of these diseases has long been obscure, butnephrotoxic mycotoxins, such as ochratoxin A, (OA) have recently emerged as

key factors. Ochratoxins are produced by several Aspergillus and Penicilliumspecies, OA being the most potent known animal nephrotoxin, producing

kidney and liver tumours in two rodent species. Regulatory limits for the levelsof OA in selected foods and feed have been set by several countries.

New data on environmental occurence and human biomonitoring using newanalytical methods are reviewed in this volume. An increasing body of data

suggests that mycotoxin exposure is associated with nephropathy of people inthe Balkan region where exposure may be endemic. The toxic effects of OA are

described, including suppression of natural killer cells, inhibition of specificenzymes and induction of lipid peroxidation, adverse effects are also dealt with

in this volume. Other contributions deal with the roles of genetics and drugmetabolism in the nephrotoxic and carcinogenic effects.

International Agency for Research on Cancer Scientific Publications No. 115

92-832-2115-X, 358 pp., illus., paperback (OUP/IARC), January 1992 £45.00

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Regular features include: For theRecord - useful data which is notappropriate as a full paper.Sequence Update - recent databaseentries available on the EMBL FileServer. Surveys and Summaries -brief reviews which bring togethermaterial not often found in aformal review article.Vol. 21,1993,24 issues + 1 supplement

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