overview of outcome data of potential meditation training for

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MILITARY MEDICINE, 176, 11:1232, 2011 1232 MILITARY MEDICINE, Vol. 176, November 2011 INTRODUCTION The high incidence of post-traumatic stress disorder (PTSD), suicides, and other adverse events in returning Operation Iraqi Freedom/Operation Endurance Freedom veterans 1,2 has made soldier (and family) resilience, defined as “the ability to meet challenges and to bounce back after difficult experiences,” 3 a priority for the Army. The mandatory Comprehensive Soldier Fitness (CSF) program requires soldiers to self-administer the Global Assessment Tool (GAT) and then segue online into Resilience Training (RT) currently comprising vignettes and didactic material. As the CSF is new and has as yet no clear “gold standard” metric for resilience in soldiers (nor does most published research 4 ), data prospectively confirming the efficacy of current RT are not yet available. 5,6 Modalities for future training are in development. In years to come, as sol- diers continue to take the GAT and then select training, it is appropriate that the training opportunities would not be lim- ited to a recapitulation of perhaps previously mastered edu- cational material and would include tools for development of high-level wellness and performance. Decisions regarding such training will need to be based upon inferences from the body of research that does exist regarding similar or related areas in the field of self-development. This analysis assumes that there are direct relationships between resilience and parameters such as enhanced physical health, freedom from anxiety and distress, improved social integra- tion and better family and workplace relationships, decreased substance abuse, and the other metrics reviewed herein. It fur- ther assumes that any training added to current RT will be evidence-based and amenable to execution in an operational environment. All such tools or activities should be portable and incon- spicuous (as practices that invite stares are unlikely to be acceptable to soldiers). For example, although no one should expect soldiers to practice eyes closed techniques while they need to pay attention to their environment, any such tech- nique should be possible to practice in “downtime” even while wearing cumbersome equipment, perhaps while in a vehicle, airframe, or austere setting. It should not require privacy, the cooperation or service of another person, nor further in- theater support or training. The modality should produce desired perceptible results promptly; training to standard should not add an undue burden of training time. Interpreting data from the fields of cognitively oriented self-development and resilience is a challenge. MEDLINE searches for resilience and self-development do not reveal many controlled studies. 7,8 This article focuses on the arena of eyes closed seated meditative techniques, widely known and studied as “stress management” or “relaxation techniques.” Interpreting data from meditation and relaxation also is not simple. Although experts in their fields (including abbots of monasteries and leaders of ashrams) readily distinguish the procedures, objects, contents, and goals of their meditation practices, 9 many researchers are indiscriminate in combining data from a number of different techniques; the value of their conclusions is at best unclear. 10–12 In fairness to those authors, some meditative or relaxation approaches are quite fuzzy in differentiating their procedures from each other. Comparison of both electroencephalographic and fMRI studies 13–15 reveals that those techniques so compared, insight meditation, Vipassana or mindfulness meditation, Tibetan Buddhist “unconditional loving-kindness and compassion,” and Transcendental Meditation (TM), show characteristic and reproducible findings that are readily distinguishable from one another. As one of the authors notes, “Brain patterns are a language that cuts across differences in cultures, worldviews, and emotionally vested terms that can cloud consideration of different meditation practices”. 13 This review demonstrates that different techniques from different traditions differ in procedure, have different effects Overview of Outcome Data of Potential Meditation Training for Soldier Resilience COL Brian Rees, MC USAR ABSTRACT In order to identify potential training to enhance comprehensive soldier fitness, this analysis searched MEDLINE via PubMed and elsewhere for 33 reasonably significant modalities, screening over 11,500 articles for rel- evance regarding soldier resilience. Evaluation of modalities that are exclusively educational or cognitive/behavioral in nature is deferred. Using the volume and quality of research over 40 parameters distributed among the five domains of resilience (physical, emotional, spiritual, social, and family life), these data allow culling of most of the meditative modalities and discrimination among the remaining techniques. The resulting order of merit is Transcendental Meditation, mindfulness, and progressive muscle relaxation. Transcendental Meditation, mindfulness, and progressive muscle relax- ation, in that order, have the most supporting data. Fortuitously, they also represent a cross section of the domain of tech- niques regarded as meditation, stress management, or relaxation, with three very different mechanisms of action. They are suitable potential options for improving soldier resilience. 63rd Regional Support Command, Moffett Field, CA 90435. Downloaded from https://academic.oup.com/milmed/article/176/11/1232/4345305 by guest on 20 August 2022

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MILITARY MEDICINE, 176, 11:1232, 2011

1232 MILITARY MEDICINE, Vol. 176, November 2011

INTRODUCTION The high incidence of post-traumatic stress disorder (PTSD), suicides, and other adverse events in returning Operation Iraqi Freedom/Operation Endurance Freedom veterans 1,2 has made soldier (and family) resilience, defi ned as “the ability to meet challenges and to bounce back after diffi cult experiences,” 3 a priority for the Army. The mandatory Comprehensive Soldier Fitness (CSF) program requires soldiers to self-administer the Global Assessment Tool (GAT) and then segue online into Resilience Training (RT) currently comprising vignettes and didactic material. As the CSF is new and has as yet no clear “gold standard” metric for resilience in soldiers (nor does most published research 4 ), data prospectively confi rming the effi cacy of current RT are not yet available. 5,6 Modalities for future training are in development. In years to come, as sol-diers continue to take the GAT and then select training, it is appropriate that the training opportunities would not be lim-ited to a recapitulation of perhaps previously mastered edu-cational material and would include tools for development of high-level wellness and performance.

Decisions regarding such training will need to be based upon inferences from the body of research that does exist regarding similar or related areas in the fi eld of self-development. This analysis assumes that there are direct relationships between resilience and parameters such as enhanced physical health, freedom from anxiety and distress, improved social integra-tion and better family and workplace relationships, decreased substance abuse, and the other metrics reviewed herein. It fur-ther assumes that any training added to current RT will be evidence-based and amenable to execution in an operational environment.

All such tools or activities should be portable and incon-spicuous (as practices that invite stares are unlikely to be acceptable to soldiers). For example, although no one should

expect soldiers to practice eyes closed techniques while they need to pay attention to their environment, any such tech-nique should be possible to practice in “downtime” even while wearing cumbersome equipment, perhaps while in a vehicle, airframe, or austere setting. It should not require privacy, the cooperation or service of another person, nor further in-theater support or training. The modality should produce desired perceptible results promptly; training to standard should not add an undue burden of training time.

Interpreting data from the fi elds of cognitively oriented self-development and resilience is a challenge. MEDLINE searches for resilience and self-development do not reveal many controlled studies. 7,8 This article focuses on the arena of eyes closed seated meditative techniques, widely known and studied as “stress management” or “relaxation techniques.”

Interpreting data from meditation and relaxation also is not simple. Although experts in their fi elds (including abbots of monasteries and leaders of ashrams) readily distinguish the procedures, objects, contents, and goals of their meditation practices, 9 many researchers are indiscriminate in combining data from a number of different techniques; the value of their conclusions is at best unclear. 10–12 In fairness to those authors, some meditative or relaxation approaches are quite fuzzy in differentiating their procedures from each other.

Comparison of both electroencephalographic and fMRI studies 13–15 reveals that those techniques so compared, insight meditation, Vipassana or mindfulness meditation, Tibetan Buddhist “unconditional loving-kindness and compassion,” and Transcendental Meditation (TM), show characteristic and reproducible fi ndings that are readily distinguishable from one another . As one of the authors notes, “Brain patterns are a language that cuts across differences in cultures, worldviews, and emotionally vested terms that can cloud consideration of different meditation practices”. 13

This review demonstrates that different techniques from different traditions differ in procedure, have different effects

Overview of Outcome Data of Potential Meditation Training for Soldier Resilience

COL Brian Rees , MC USAR

ABSTRACT In order to identify potential training to enhance comprehensive soldier fi tness, this analysis searched MEDLINE via PubMed and elsewhere for 33 reasonably signifi cant modalities, screening over 11,500 articles for rel-evance regarding soldier resilience. Evaluation of modalities that are exclusively educational or cognitive/behavioral in nature is deferred. Using the volume and quality of research over 40 parameters distributed among the fi ve domains of resilience (physical, emotional, spiritual, social, and family life), these data allow culling of most of the meditative modalities and discrimination among the remaining techniques. The resulting order of merit is Transcendental Meditation, mindfulness, and progressive muscle relaxation. Transcendental Meditation, mindfulness, and progressive muscle relax-ation, in that order, have the most supporting data. Fortuitously, they also represent a cross section of the domain of tech-niques regarded as meditation, stress management, or relaxation, with three very different mechanisms of action. They are suitable potential options for improving soldier resilience.

63rd Regional Support Command, Moffett Field, CA 90435.

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in brain and body, and have quite distinguishable clinical and psychological outcomes. These outcomes suggest some to be more suitable for enhancing soldier resilience than others.

METHODS This analysis used the following steps:

(1) Identifi es assumptions and screening criteria regarding training modalities for soldier resilience.

(2) Through MEDLINE searches and informally through contacts in the Army, identifi es signifi cant candidates for training modalities ( Table I ).

(3) Eliminates candidates who do not meet screening criteria.

(4) Searches MEDLINE via PubMed to determine the vol-ume of research done on the candidates ( Table II ).

(5) Eliminates those candidates without an adequate base of data to support them.

(6) Via searching MEDLINE as well as visiting Web sites for techniques known to be under consideration, com-poses a list of outcome parameters relevant to soldier

resilience that have been used (and published) to study the top candidates.

(7) Synopsizes the studies; reviews or meta-analyses that directly compare any of the selected modalities to one another are discussed, other studies listed in Table III .

(8) Discusses the fi ndings and constructs an order of merit list for the modalities that survived scrutiny.

(9) Makes recommendations based upon the fi ndings.

RESULTS

First Round Cuts as a Result of Feasibility Issues Three of the modalities listed in Table I do not meet the “aus-terity” criteria listed in the introduction and thus do not make the fi rst cut: pranayama includes breathing exercises that would be too conspicuous on an airplane or in an open bay; hatha yoga requires loose fi tting clothing and a fl at comfort-able surface (no go while wearing body armor, or in a vehicle, or living and sleeping in the dirt); and reiki requires the thera-peutic touch of a reiki practitioner.

TABLE I. List of Training Approaches Initially Considered (Alphabetical)

1 Battlemind2 Biofeedback3 Biofeedback (EMG)4 Boot Strap /STARS/Stress Gym Interventions5 Compassion Training6 Concentration7 Corporate Meditation (Thornton)8 Kripalu Meditation9 Mantra Meditation (Other Than TM)

10 Meditation (Any Other, Not Otherwise Specifi ed)11 Mindfulness Based Mind Fitness Training (by Jha)12 Mindfulness Based Stress Reduction (by Kabat-Zinn)13 Mindfulness Meditation (AKA Vipassana or Insight)14 One Shot-One Kill15 Penn Resiliency Program16 Pranayama17 PMR18 Qi Gong19 RR (Benson)20 RR Meditation21 Relaxation (other)22 Reiki23 Samurai Mind Training24 Soft Belly Meditation25 Super Calm Meditation26 Tibetan Buddhist Meditation27 Total Awareness28 Transactional Analysis29 TM30 Warrior Mindfulness31 Yoga, Hatha32 Yoga Medics33 Zen Meditation

TABLE II. Volume of Research

Training/Modality

Number of Studies Found in PubMed

1 Biofeedback 6,0832 TM 1,7213 PMR 7614 Transactional Analysis 4815 Mindfulness Meditation 3636 Concentration Meditation 2317 Mindfulness-based Stress Reduction

(Kabat-Zinn)173

8 Biofeedback (EMG)/Stress Related 1,396/1459 RR Meditation 102

10 Qi Gong (Chi Gung ~ Pranayam and/or Mindfulness)

90

11 Zen Meditation 6012 RR (Benson) 5813 Mantra Meditation (Other Than TM) 1014 Tibetan Buddhist Meditation 915 Total Awareness (Mindfulness or TM) 816 Compassion Training (Military, Other

Than Nurse Training)7

17 Penn Resiliency Program 618 Battlemind 3, Plus Those

Not Yet Published19 Boot Strap/STARS/Stress Gym

Interventions3

20 Mindfulness-based Mind Fitness Training (Jha)

2

21 Kripalu Meditation 122 One Shot-One Kill 123 Warrior Mindfulness 124 Corporate Meditation (Thornton) 025 Samurai Mind Training 026 Soft Belly Meditation 027 Super Calm 028 Yoga Medics 0

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1234 MILITARY MEDICINE, Vol. 176, November 2011

Second Round Cuts as a Result of Defi ciencies in Evidence-based Outcome Data Starting with the least researched, this analysis eliminates yoga medics, super calm meditation, soft belly meditation, samurai mind training, corporate meditation, warrior mindful-ness, kripalu meditation (assuming that the previous three are separate from other mindfulness discussed below), compas-sion training, Tibetan Buddhist meditation, and mantra medi-tation other than TM. These approaches may have value, but it is beyond the scope of this article to discern what that value might be. If they are to be included in the training modules for soldier resilience, inclusion would have to be for reasons other than evidence-based outcome data.

Nonspecifi c relaxation and meditation cannot be distin-guished from more specifi c modalities and thus are not con-sidered separately.

The three categories of mindfulness above, as well as the categories of both concentration and Zen meditation, 16 are fairly indistinguishable; searches for one or the oth-ers often identify the same articles, and the methodologies appear to overlap, with perhaps some proprietary differences opaque to this analysis. Qi Gong references variably describe both pranayama and mindfulness; “total awareness” arti-cles refer to either TM or mindfulness. Qi Gong and total awareness are cut. Although there may be signifi cant differ-ences among mindfulness techniques, they are not yet fully elucidated; for purposes of this evaluation, all mindful-ness, Zen, insight meditation, Vipassana, and concentration, whether done with eyes closed or executed during activ-

ity or both, are retained but rolled up into a single category: mindfulness.

The Army’s Battlemind Training (the precursor to RT) has been studied as employed after the combat stress event. 17,18 The Penn Resiliency Program (PRP) 19–22 and the One Shot-One Kill, Boot Strap, STARS, and Stress Gym 23–29 interventions have not been compared to one another; information is insuffi -cient for this review to distinguish among these programs nor to compare them meaningfully to the meditative techniques considered. This analysis assumes that online behavioral and coping skills RT such as that currently available through the Army Knowledge Online link of the CSF program and face-to-face training such as the PRP (or its cousins, progeny, or successors) are here to stay, but will not be further discussed in this article.

The proponents of relaxation response (RR), a technique derived from TM, contend that stress management and relax-ation and meditation techniques are all essentially the same. As a result of that assumption, they often borrow data freely from other specifi c techniques and attribute the results to the RR. 30 This contention is confusing and is not supported by neuroimaging data, 13 nor by meta-analyses or compara-tive studies. 31–33 But since its proponents also claim it can be learned from a book and is thus simple and inexpensive, it is tempting to include RR in further discussion. Three consid-erations militate against inclusion. First, its core assumption (of universal equivalence of techniques) appears unredeem-able. 13,31 Second, by its advocates’ own assertions, it is deriv-ative: it brings nothing new or different to the fi ght. Third, available data demonstrate that it is inferior in its outcomes, whenever data exist to compare, 31–33 to at least one other tech-nique (TM) under consideration. For these reasons, RR is eliminated.

Biofeedback does not make the cut. Although it has thou-sands of citations, they mostly have to do with specifi c clini-cal entities such as incontinence or tinnitus, and the studies related to stress reveal very little applicable to resilience or the types of holistic fi tness or continuous self-development objec-tives of CSF.

Transactional analysis does not make the cut; it has not been signifi cantly studied. The culling above leaves three training modalities:

mindfulness — progressive muscle relaxation (PMR) — TM —

Descriptions of the Modalities and Differentiating Brain Effects Mindfulness is traditional with some modern cognitive ele-ments; its effects are mediated by changing the interpretation of internal and environmental cues and by enhancing cop-ing skills. PMR is a modern laboratory-derived technique, which promotes muscular and subsequent mental relaxation. TM is a traditional technique, effecting changes in physical,

TABLE III. References for the 3 Modalities Relevant to CSF Domains

Domain TM Mindfulness PMR

Physical Hypertension 64–69 — — CV Disease and Risk 70–76 — — Tobacco, Alcohol, and

Substance Abuse83–87 37,77–82 88

HPA Axis, Lipids, Hormones, and Aging

90–99 89 —

Stress Reactivity and Reaction Time

46,58,100–103 — —

Pain 113,114 106–112 104,105Emotional and Spiritual Intelligence, Cognition,

and Academics102,115–120 121–123 —

Creativity and Morals 62,124–132 — — Anxiety and Depression 151–154 38,133–148 149,150 Sleep, Attention defi cit

hyperactive disorder, and PTSD

157–159,161 155,160 156

Social and Family Marital and Family 162,163 — — Discipline and Legal 164–169 — — Leadership, Effi ciency,

Tolerance, Social and Workplace Integration

170–183 — —

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psychological, and social health and behavior through changes in brain (and related physiological) functioning.

Mindfulness A variety of practices are fall under the rubric of “mindful-ness,” which is commonly defi ned as a:

…dispassionate, non-evaluative and sustained moment-by-moment awareness of perceptible mental states. This includes continuous, immediate awareness of physical sensations, perceptions, affective states, thoughts, and imagery. Mindfulness is non-deliberative. It merely im -plies sustained paying attention to mental content without thinking about it, comparing or in other ways evaluating the ongoing mental phenomena that may arise during periods of practice. 34

Mindfulness meditation is described as a systematic pro-cedure to develop enhanced awareness of moment-to-moment experiences. Mindfulness can include at least two meditation practices:

with eyes closed: attention on breath — with eyes open: dispassionate observation of body, —senses, and environment. This meditation involves inten-tion or directing of attention to physiological rhythms, inner thoughts, sensations, or outer objects.

Though derived from a Buddhist background, mindfulness is not a religion, does not require faith, and is compatible with any religious tradition.

Mindfulness is negatively correlated with resting activity in the amygdala bilaterally, as opposed to depressive symptoma-tology positively correlated with amygdalar activity. 35 During an “affect labeling” task of dispositional mindfulness, func-tional magnetic resonance imaging reveals widespread pre-frontal cortical activation and reduced amygdalar activity. 36 A review of 7 “mainly poor quality studies” of Vipassana mindfulness included 3 with neuroimaging results, showing activation of prefrontal and anterior cingulate cortex. 37 Patients suffering from social anxiety disorder completing a course in mindfulness-based stress reduction (MBSR) showed reduced amygdalar activity and “increased activity in brain regions implicated in attentional deployment” 38 during one of two mind-fulness tasks; healthy subjects had increased regional gray matter density after the MBSR course. 39 A review of Zen meditation showed an increase in alpha and theta waves frontally. 16

Per a mindfulness instructor contacted by this author, a course in mindfulness was to include six sessions, a full day retreat and then a fi nal session, with ~15 hours of contact time. As of 2008, the cost was $100 an hour per person or $1,500 for each individual. This course and fee structure may or may not be typical. Per its website, MBSR in 2010 had fees from $450 to $600 depending upon income.

Mindfulness is taught by many psychologists, Masters of Social Work, and other individuals. Some programs (such as MBSR) are fairly standardized. There is no umbrella organi-

zation that determines or enforces a standard for all mindful-ness practice or instruction.

Progressive Muscle Relaxation Descriptions of PMR abound. That in Wikipedia 40 is typical:

… a technique of stress management developed by American physician Edmund Jacobson in the early 1920s. 41 Jacobson argued that since muscular tension accompanies anxiety, one can reduce anxiety by learning how to relax the muscular tension….

PMR involves alternately tensing and relaxing the mus-cles. 42 A person practicing it may start by sitting or lying down in a comfortable spot and taking some deep breaths, and then he or she will proceed to tense, then relax, groups of mus-cles in a prescribed sequence…. The effect of the tension–relaxation sequence is to cause deeper relaxation than would be achieved by simply attempting to relax.

In theory, one can practice PMR on one’s own after simply reading some instructions, with perhaps some guidance as to which muscles to involve in what order. PMR also is commonly taught by therapists from many disciplines, including physical and occupational therapists. Fees for such services are variable.

Transcendental Meditation TM is an effortless purely mental technique, practiced for 15 to 20 minutes twice daily, seated with eyes closed, requiring no other changes in lifestyle. It comes from the Vedic tradi-tion of India and was popularized over the last 50 plus years by the late Maharishi Mahesh Yogi. Like mindfulness, it is not religious in nature. It uses what proponents describe as the “natural tendency of the mind” to move toward greater enjoy-ment and charm, effecting “automatic self-transcending” 43 ; during the practice, the mind easily moves toward subtler levels of thought and can “transcend” thinking altogether, allowing the mind and body to experience “restful alertness,” a state of unique and salubrious mental and physiological functioning.

Physiologically, restful alertness is associated with a state of rest, as refl ected in decreased metabolism, respiration rate, and blood fl ow to the limbs, decreased sympathetic activity, 44 and increased mental alertness, as refl ected in higher frontal electroencephalogram (EEG) coherence. 45 This experience allows the body to remove effects of previous stressors and to be more resilient to current stressors. 46

Restful alertness is associated with both activation of atten-tional systems and deactivation of thalamic input circuits in a positron emission tomography study 15 and higher frontal EEG coherence—a measure of functional connectivity. 47,48 The expe-rience and associated brain state of restful alertness during TM practice is refl ected in long-term changes in brainwave patterns during tasks outside of meditation practice—broadband frontal coherence, normally seen during TM practice, is progressively seen during challenging tasks with regular TM practice, 47–49 enhancing frontal executive functioning. 50 Multiple studies

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have documented characteristic EEG fi ndings in TM; within the practice, power and alpha coherence increases, 48,50–53 coher-ence which increased within 2 weeks of practice. 54

TM is proprietary and standardized. All TM instruction is performed only by teachers certifi ed to teach TM by the global TM organization. The course of instruction is always the same, involving fi ve sessions in the fi rst week followed by optional “checking” weekly for the fi rst month and monthly for the fi rst year. As of early 2011, the U.S. course fee is $1,500 per person, with a discount to $1,200 per person for groups (fam-ily rates, military rates as low as $750, and low-income schol-arships also exist). Follow-up (“checking”) is included in the course fee, lifelong and worldwide, as frequently as may be desired by the TM meditator.

Head-to-Head Comparisons and Meta-analyses

Comparing PMR and TM

In the fi rst of two prospective randomized controlled trials (RCTs) of hypertensive African-Americans, the TM group had signifi cantly decreased blood pressure compared to the PMR group and to usual care in a 3-month study of 150 subjects. 55 These fi ndings were replicated in the second RCT, a 1-year-long study of 127 subjects. The TM group decreased its use of anti-hypertensive medication; the PMR group increased its use. 56

Comparing PMR and Mindfulness

In this 1-month RCT, 83 distressed college students were randomized to mindfulness, “somatic relaxation,” or a no-treatment control. Both the mindfulness and relaxation groups similarly decreased distress and increased positive mood. Mindfulness was more effective in decreasing distractive and ruminative thought behaviors than was PMR or control. 57

Comparing TM and PMR

Eighty-three African-American college students were ran-domized to TM, PMR, or “cognitive strategies.” A year later, both the TM and PMR groups were signifi cantly improved in mental health and anxiety; TM showed greater reduction in neuroticism compared to both PMR and cognitive strategies. The TM group showed increased EEG coherence compared to eyes closed, other groups did not. The TM group had faster habituation to stressful stimuli than did the PMR group. 58

Comparing TM and PMR

Older hypertensives randomized to TM, PMR, or usual care were followed for mortality for a mean of 7.6 years. The TM group had 23% less all-cause mortality, 30% less cardiovas-cular mortality, and 49% less cancer mortality than combined controls. 59

Comparing Mindfulness and TM (and RR)

Seventy-three elderly were randomized to TM, mindfulness, or RR. The TM group had signifi cantly better cognitive func-tion, mental health, blood pressure, and survival compared to the other groups. 32 Eight- and fi fteen-year follow-ups con-

fi rmed TM group superiority in both cardiovascular and all-cause mortality. 60

Meta-analysis of PMR and TM (and Biofeedback) in Hypertension

TM signifi cantly outperformed PMR (and biofeedback) in reduction of blood pressure among hypertensives. 61

Meta-analysis of TM, PMR, and Other Meditations in Trait Anxiety

In 146 studies, the effect size for TM was more than double that of the others, including placebo, PMR, and other medita-tions including mindfulness, (and non-TM mantra meditation, biofeedback, and RR). 33

Meta-analysis of TM, Relaxation, Other Meditation (Including but Not Specifying Mindfulness)

In 42 studies, the effect size for TM was 3 times that of relax-ation and other meditation in increasing self-actualization. 62

Meta-analysis of TM, PMR, and Mindfulness (and Numerous Other Modalities)

In eight meta-analyses of 597 studies of over 20,000 subjects, TM signifi cantly outperformed other modalities across a host of outcomes, including improved psychological outcomes and decreased use of cigarettes, drugs, and alcohol. 31

A review and meta-analysis of 27 studies concluded that “meditation” was more effective than progressive relaxation, autogenic training, and applied relaxation in reducing anxiety. 63

Studies of the 3 Modalities CSF Parameters The Army’s CSF Program recognizes fi ve domains of life that require fi tness/wellness for the soldier to function optimally: physical, emotional, spiritual, social, and family. Table III cites the extant literature regarding the three selected techniques. 37,38,47,58,62,64–183

DISCUSSION Discussion is along four axes: effi cacy, acceptability, quality control, and cost.

Effi cacy Limitations to the determination of effi cacy are at least three: there may be signifi cant distinctions between resilience, as desired by the U.S. Army, and the parameters cited in this evaluation; mindfulness and more so PMR have not been studied at all in some CSF domains ( Table III ); and the stud-ies cited were almost universally not performed on American soldiers.

Of the three modalities, mindfulness, PMR, and TM, avail-able data support TM as the most effi cacious in virtually all the outcomes studied to date. 31 TM has the greater volume of supporting research (with the exception of a larger vol-ume of studies on mindfulness and pain) and more high-quality studies (prospective randomized controlled design) than the other two approaches. Virtually all the meta-analyses and

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comparative studies show greater effect sizes for TM in con-ditions from hypertension 56,60,61 to anxiety 33 to mortality, 32,60 in populations varied in age, ethnicity, and nationality.

Confl icting data inhibit conclusions regarding the relative effi cacy of mindfulness versus PMR. PMR may reduce anxi-ety 63 and substance abuse 88 ; the physiological underpinning of the cognitive improvements is as yet undetermined. 88 Some reviewers conclude that mindfulness has effi cacy in stress reduction 140,141,184 and a variety of other health issues. 139 Others conclude that it does not have a reliable effect on depres-sion or anxiety 145 and has equivocal fi ndings for sleep distur-bance 155 and that the paucity of research does not support a strong endorsement of this approach. 185

Acceptability There are no data to indicate that any one of the modalities would be more or less acceptable to soldiers than the others.

PMR is lab-generated with no elements from a non-Western culture. It may be more attractive to soldiers with muscular tension issues or those not comfortable with any form of “meditation.” PMR appears to be simple and have a modest time requirement and gentle learning curve although one review of 29 studies with various psychophysiological outcomes indicated that its effects are greater with more ses-sions, individualized treatment, and greater treatment dura-tion. 186 There is no evidence of poor acceptability.

TM is unabashedly traditional. Professional teachers describe its origins in the Vedic tradition of India when intro-ducing prospective students. Personal instruction in TM is always done on a one-to-one basis, in private. Also, it is pro-prietary; students are asked to keep their instruction private. In addition, “dabbling” in TM is actively discouraged. Teachers ask prospective students to commit to make and take the time to be regular in their twice-daily practice of TM, asserting that greater effi ciency and enjoyment more than make up for the time spent meditating. These points may constitute barriers to learning TM for some soldiers. In the challenging population of psychiatric inpatients, TM was “more readily accepted with longer compliance than training in progressive relaxation or EEG alpha rhythm enhancement.” 187

The term “unique” is often used when describing TM; this term is a red fl ag for many. 188–190 TM proponents explain “unique” thusly: automatic self-transcending is an innate human capability, but there are more and less effi cient ways to reach that state, and the technique to elicit it is acquired. TM advocates quote their data and say that, by virtue of its long, many millennia-old tradition, TM is “uniquely” effi cient in bringing about that healthy style of functioning in mind and body.

Mindfulness may be somewhat between TM and PMR in the areas discussed above. It is traditional; not as overtly as TM, but more than PMR. Acceptability may be a function of local issues as mindfulness is not standardized; but at least one program demonstrated 88% of participants still meditating after 4 months. 108 In a 2009 study, mindfulness was acceptable

when added to behavioral interventions in a family-focused adolescent drug prevention program. 191 Time requirements for mindfulness may be comparable to PMR and TM. Long-term follow-up requirements have not been specifi ed.

Quality Control Mindfulness and PMR are both taught by a variety of thera-pists and counselors or in theory could be self-taught. Reliance upon qualifi ed personnel should be adequate.

TM is always taught by certifi ed TM teachers. A program of mandatory ongoing recertifi cation of instructors assures good quality control.

Cost There are no published data demonstrating any signifi cant risks associated with the practice of any of the three modali-ties. Indeed, a study by the Swedish National Health Board in 1975 found that hospitalization for psychiatric care was 150 to 200 times less common for TM practitioners than for the general population. 192 However, it is inevitable that some unfortunate young soldier who is destined to experience his or her initial psychotic break will do so soon after having been trained in one of the modalities; some stakeholders may see a cause–effect relationship where one has not been shown to exist.

Costs for TM and for mindfulness may be comparable. The cost for PMR may be less depending on the nature of contract-ing for individuals to instruct PMR.

TM has demonstrated lower health care utilization and costs. 193–198 This may make TM attractive to soldiers, fami-lies, and organizations responsible for providing their medi-cal and mental health services as the costs to society from combat-related PTSD alone are in the billions of dollars per year. 1 Mindfulness and PMR may have as yet undemonstrated benefi cial effects on health costs. The magnitude of those sav-ings, if any, is unknown.

RECOMMENDATIONS

(1) Include one or more of the three modalities in the menu of training options for the promotion of soldier resilience, in this order: TM, a form of mindfulness, and PMR.

(2) After proper Institutional Review Board vetting, ran-domize soldiers in unit(s) about to deploy to be trained in either one of the three recommended modalities or in a “usual care” control group. During and after deploy-ment, measure performance on the GAT, the incidence of PTSD, Uniform Code of Military Justice actions, administrative discharges, divorces, substance abuse, and other physical, psychological, and behavioral health endpoints.

(3) Adopt or develop metrics adequate to measure antici-pated high-level growth in the domains of CSF (phys-ical, emotional, spiritual, family, and social) as a result of this training; alternatively, the GAT could be

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expanded and revalidated to accomplish this. Study a selected subpopulation with more in-depth physiologi-cal and psychological tests and neuroimaging.

(4) Use the Soldier Fitness Tracker to identify the most effective of the training modalities.

(5) Adopt the “best practice”’ identifi ed by recommenda-tions (2) and (4) and disseminate throughout the Army.

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