dna testing goes to the dogs

1
News News News News C anine DNA testing is now available in Australia and appears set to be mandatory for all pure bred dogs used as frequent studs and donor sires for artificial insemination from January 2006. Endorsed by the Australian National Kennel Council (ANKC) in May 2004, the Australian Canine Pedigree Assurance Program is being conducted by Genetic Technologies Limited (GTG) at its Melbourne laboratory. GTG, (through its molecular genetics division), has been performing commercial genotyping since the late 1980’s and all the canine DNA results are ANKC certified with dog owners being issued with a certificate to establish their animal’s paternity and pedigree. The innovative program allows authorised collection officers including veterinarians, to gather non-invasive buccal swab samples for DNA analysis. The ANKC insists all dogs must be microchipped or tattooed prior to having the sample taken to ensure that the dog being tested is positively identified and correct. Veterinarians need to obtain collection kits from GTG before collection and can charge a nominal fee for providing the service. While many breeders have expressed their desire to test through veterinarians, GTG also plans to train members for each of the major breed associations to collect at state and national breeding shows. “If someone does question a sibling and its parentage, it will be on a DNA database for them to verify,“ says George Sofronidis, GTG’s Manager of Animal Diagnostics. “Families buying pure bred puppies will have peace of mind when they take the newest family member home with a DNA certificate, attesting that it is pure bred and free from disease.” In Australia the Greyhound Racing Association and pure breed horse associations already have mandatory DNA typing programs for parentage testing and by January 2008 all stud sires will need to be DNA profiled. If the owner/breeder desires, the dog can also be checked to see whether it has, or carries, an inherited disease. Mr Sofronidis says the testing provides an effective method of disease prevention without the need to cull any breeding stock. GTG are working in close association with ophthalmologist Dr Robin Stanley who has been taking samples from PRA (Progressive Retinal Atrophy) affected dogs with owner consent and Professor Bruce Parry at Werribee Veterinary Clinic who’s assisted the company to gather samples for Canine von Willebrand in Dobermans and Scottish Terriers. “So far all forms of von Willebrand disease type 1-3 have been evaluated in our offering, PRA and Clad in Irish Setters and we’re still developing the linkage based tests on PRA and VRCD in cocker spaniels,” said Mr Sofronidis. “What we’re hoping is that a breed will come to us with a disease they see as being a big issue and then we’ll discuss this with vets and the ANKC and animal health committees and if people are in agreeance we will develop tests for the disease.” “We’re trying to ensure that everything we offer is relevant to Australian pedigrees and that’s why we want to develop our own database for all these diseases.” There are currently genetic tests for approximately 50 canine hereditary diseases across various breeds, but to date few Australian dogs have been tested due to largely inconvenient and expensive overseas testing. The new Australian Canine Pedigree Assurance Program test costs compare favourably with its American Canine DNA testing equivalent. Clients can expect to pay up to $65 for a DNA profile or parentage and from $154-$297 for hereditary disease testing depending on the test to be performed. DNA Testing goes to the Dogs By Mark Thornley

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Page 1: DNA Testing goes to the Dogs

NewsNewsNewsNews

Canine DNA testing is now availablein Australia and appears set to bemandatory for all pure bred dogs

used as frequent studs and donor sires forartificial insemination from January 2006.

Endorsed by the Australian NationalKennel Council (ANKC) in May 2004, theAustralian Canine Pedigree AssuranceProgram is being conducted by GeneticTechnologies Limited (GTG) at itsMelbourne laboratory.

GTG, (through its molecular geneticsdivision), has been performing commercialgenotyping since the late 1980’s and all thecanine DNA results are ANKC certifiedwith dog owners being issued with acertificate to establish their animal’spaternity and pedigree.

The innovative program allowsauthorised collection officers includingveterinarians, to gather non-invasive buccalswab samples for DNA analysis. TheANKC insists all dogs must bemicrochipped or tattooed prior to havingthe sample taken to ensure that the dogbeing tested is positively identified andcorrect.

Veterinarians need to obtain collectionkits from GTG before collection and cancharge a nominal fee for providing theservice. While many breeders haveexpressed their desire to test throughveterinarians, GTG also plans to trainmembers for each of the major breedassociations to collect at state and nationalbreeding shows.

“If someone does question a sibling andits parentage, it will be on a DNA databasefor them to verify,“ says George Sofronidis,GTG’s Manager of Animal Diagnostics.

“Families buying pure bred puppies willhave peace of mind when they take thenewest family member home with a DNAcertificate, attesting that it is pure bred andfree from disease.”

In Australia the Greyhound RacingAssociation and pure breed horseassociations already have mandatory DNAtyping programs for parentage testing andby January 2008 all stud sires will need tobe DNA profiled.

If the owner/breeder desires, the dog canalso be checked to see whether it has, orcarries, an inherited disease. Mr Sofronidissays the testing provides an effectivemethod of disease prevention without theneed to cull any breeding stock.

GTG are working in close associationwith ophthalmologist Dr Robin Stanleywho has been taking samples from PRA(Progressive Retinal Atrophy) affected dogswith owner consent and Professor Bruce

Parry at Werribee Veterinary Clinic who’sassisted the company to gather samples forCanine von Willebrand in Dobermans andScottish Terriers.

“So far all forms of von Willebranddisease type 1-3 have been evaluated in ouroffering, PRA and Clad in Irish Setters andwe’re still developing the linkage based testson PRA and VRCD in cocker spaniels,”said Mr Sofronidis.

“What we’re hoping is that a breed willcome to us with a disease they see as beinga big issue and then we’ll discuss this withvets and the ANKC and animal healthcommittees and if people are in agreeancewe will develop tests for the disease.”

“We’re trying to ensure that everythingwe offer is relevant to Australian pedigreesand that’s why we want to develop our owndatabase for all these diseases.”

There are currently genetic tests forapproximately 50 canine hereditary diseasesacross various breeds, but to date fewAustralian dogs have been tested due tolargely inconvenient and expensive overseastesting.

The new Australian Canine PedigreeAssurance Program test costs comparefavourably with its American Canine DNAtesting equivalent. Clients can expect to payup to $65 for a DNA profile or parentageand from $154-$297 for hereditary diseasetesting depending on the test to beperformed.

DNA Testing goes to the DogsBy Mark Thornley