diagnostic test in hematology
TRANSCRIPT
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HEMATOLOGIC DISORDERS: DIAGNOSTIC
TESTSBY: JOHN ARBIE T. TATTAO, RN
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A. Blood Examinations (CBC) Used to monitor a patient’s
progress response to treatment Most common laboratory test:
Hgb and Hct levels1. Hgb test : measures the amount
of Hgb in the peripheral blood by weightHct test : measures the ratio of RBC volume to the whole blood volume
I. LABORATORY TESTS
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2. RBC Indicesa. Mean Corpuscular Volume
(MCV) – N: 80 – 95%Formula: Hct/RBCb. Mean Corpuscular Hgb (MCH)
N: 27 – 32% Mean Corpuscular Hgb Conc.
(MCHC) – N: 32 – 36%Formula: MCH: Hgb/RBC
MCHC: Hgb/Hct
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3. Reticulocyte Count – measures the number of immature RBC’s circulating in the blood
- Provides useful info. about the erythropoietic activity of the bone marrow
4. Differential WBC Count5. Platelet Count6. RBC Count
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Laboratory Test of Blood CellsTest Male Female
Hgb Levels 13 – 18 g/dl 12 – 16 g/dl
Hct Levels 45 – 52% 37 – 48%
RC 1 – 2% of total RBC Count
MCV 80 – 95%
MCHC 32 – 36%
Differential WBC Count
Neutrophils 55 – 70%
Eosinophils 1 – 4%
Basophils Up to 1%
Monocytes 2 – 6%
Lymphocytes 25 – 40%
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B. PERIPHERAL BLOOD SMEARIdentifies the color, size, shape and contents of RBC
1. Color: (Normochromic, Hypochromic)
2. Anisocytosis: (Normocytic, Microcytic, Macrocytic)
3. Poikilocytosis: (Leptocytes, Spherocytes)
I. LABORATORY TESTS
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C. Coagulation Studies1. aPTT : N: 25 – 35 secondsMeasure the number of seconds in which a clot forms
2. PT: N: 10 – 13 secondsAlso measures the time needed to form a clot, but specifically measures clotting factors (I, II, V, VII, X)
I. LABORATORY TESTS
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A. Lymphangiography A radologic technique used for
visualization of the lymphatic system flow and nodes to detect the presence or stage of disease
Radiologist makes a small incision between the toes or fingers and instills dye. An iodine-based dye is injected and rediographs are taken then and again after 24 and 48 hrs after instillation of dye
II. RADIOLOGIC TEST
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Nursing Responsibility:Pre-procedure:1. Obtain informed consent2. Assess pt. For allergy to iodine
3. Local anaesthesia is used before the needle insertion
Lymphangiography
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4. Inform patient that he may experience a sensation of warmth and flushing as the iodine based dye is injected
5. The examiner may ask the patient to walk
Post Procedure:1. Elevate affected limb for 24 hrs.
Lymphangiography
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2. Assess pt. For signs of bleeding/adverse reaction to the dye
3. Assess the affected extremity for any change in sensorimotor function
Lymphangiography
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Purposes:1. To evaluate abnormal blood
cells2. Monitor the effects of bone
marrow depressants3. Monitor the patient’s
response to treatment4. Help diagnose disorders
associated with abnormal hematopoiesis
III. BONE MARROW EXAMINATION
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1. Bone Marrow Aspiration Most common procedure for
obtaining a bone marrow sample
√Most common site for BMA: Other site: sternum,
anterior/posterior iliac spines
III. BONE MARROW EXAMINATION
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Indication of BMA:Severe anemiaThrombocytopeniaAcute leukemiaNeutropenia
III. BONE MARROW EXAMINATION
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2. Bone Marrow BiopsyIndicated when a large sample of bone marrow is needed
√Most common site of BMBOther site: sternum, proximal tibia
III. BONE MARROW EXAMINATION
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Indication of BMB:PancytopeniaLymphomaMyelofibrosisMetastatic tumorMutliple myeloma
III. BONE MARROW EXAMINATION
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Pre-procedure:1. Education, preparation, and
emotional support of the patient before bone marrow aspiration
2. Remind the pt. to lie still during the entire procedure
Post-procedure:1. Apply pressure dressing over
the aspiration site
Nursing Responsibility
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2. Advise patient to lie on the biopsied side.
3. Monitor the site every 15 minutes.
4. An ice bag maybe applied to the site
Nursing Responsibility