department newsletter july 2013 - northwestern … epting, md is an assistant professor of...

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Healthcare reform is here and will inevitably change the way medicine is practiced. Care for patients will be centered in their medical homes and coordinated by primary care physicians. Efficiencies together with the focus on measurable outcomes will improve the health of our communities and lower the overall cost of health care. Leaders of our Divisions, the Department, and Lurie Children’s have been working to prepare us for these changes, including working in more formal partnerships with our primary care physicians (Clinically Integrated Network) and the State of Illinois (Coordinated Care Entity). At the same time, we are committed to the growth and development of our clinical, education, and research programs. National searches are underway, seeking outstanding clinical and academic leaders for our Divisions of Neonatology and Hematology/Oncology/Stem Cell Transplantation and a leader for Clinical and Translational Research. Another search will soon be organized for a Division Head of Academic General Pediatrics. Reflective of the growth of our Department and our services, several new divisions have been organized and new division heads appointed. These are: Division of Hospital-based Medicine (Lurie Children’s): Robert Greenberg Division of Hospital-based Medicine (Outreach): Patricia Chiamas Division of Adolescent Medicine: Robert Garofalo Division of Child Abuse Pediatrics: Emalee Flaherty Division of Behavior/Development: Dana Brazdziunas Again, I hope you enjoy the contents of this publication. Should you have ideas for submissions going forward, please contact our Department Communications Associate, Brian von Rueden, at: [email protected]. Thank you for your ongoing work on behalf of our patients and families, and for your commitment to this department. CHAIRMAN’S UPDATE : Thomas P. Green, MD Department Newsletter July 2013 Volume 1, Issue 3 Department of Pediatrics Northwestern University Feinberg School of Medicine Ann & Robert H. Lurie Children’s Hospital of Chicag o Children’s Hospital of Chicago Research Center Phone: 312.227.3210 Fax: 312.227.9637 Email: [email protected] The Department of Pediatrics of Northwestern University Feinberg School of Medicine is dedicated to understanding and promoting optimal child health and function.

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Healthcare reform is here and will inevitably change the way medicine is

practiced. Care for patients will be centered in their medical homes and coordinated by

primary care physicians. Efficiencies together with the focus on measurable outcomes

will improve the health of our communities and lower the overall cost of health

care. Leaders of our Divisions, the Department, and Lurie Children’s have been

working to prepare us for these changes, including working in more formal partnerships

with our primary care physicians (Clinically Integrated Network) and the State of Illinois

(Coordinated Care Entity).

At the same time, we are committed to the growth and development of our clinical,

education, and research programs. National searches are underway, seeking

outstanding clinical and academic leaders for our Divisions of Neonatology and

Hematology/Oncology/Stem Cell Transplantation and a leader for Clinical and

Translational Research. Another search will soon be organized for a Division Head of

Academic General Pediatrics. Reflective of the growth of our Department and our

services, several new divisions have been organized and new division heads

appointed. These are:

Division of Hospital-based Medicine (Lurie Children’s): Robert Greenberg

Division of Hospital-based Medicine (Outreach): Patricia Chiamas

Division of Adolescent Medicine: Robert Garofalo

Division of Child Abuse Pediatrics: Emalee Flaherty

Division of Behavior/Development: Dana Brazdziunas

Again, I hope you enjoy the contents of this publication. Should you have ideas for

submissions going forward, please contact our Department Communications Associate,

Brian von Rueden, at: [email protected]. Thank you for your ongoing

work on behalf of our patients and families, and for your commitment to this department.

CHAIRMAN’S UPDATE : Thomas P. Green, MD

Depar tment Newsletter July 2013

Volume 1, Issue 3

Department of

Pediatrics

Northwestern University

Feinberg School of Medicine

Ann & Robert H. Lurie

Children’s Hospital of Chicago

Children’s Hospital of Chicago

Research Center

Phone: 312.227.3210

Fax: 312.227.9637

Email: [email protected]

The Department of

Pediatrics of Northwestern

University Feinberg School

of Medicine is dedicated

to understanding and

promoting optimal child

health and function.

Established in 1883, The Journal of the American Medical

Association (or JAMA) is one of the premier peer-edited medical

journals, released on a weekly basis. From July 2012 through

June 2013, Denise M. Goodman, Professor of Pediatrics

(Critical Care), served as the 31st Morris Fishbein Fellow in

Medical Editing at JAMA. The position involves working with

senior editorial leadership, while receiving intensive immersive

instruction in study design, analysis, and interpretation. When

articles are submitted for potential publication, they are

assigned to reviewing editors who meticulously evaluate them

and decide whether they will be sent out for peer review. If

they pass the initial step, they may still be rejected or presented

at a manuscript meeting, a twice-weekly session where the

senior and associate editors further discuss papers, evaluating

the novelty, validity, and implications of the manuscript.

For a physician normally involved with many clinical

responsibilities in the fast-paced ICU, a position focused on

literature may seem like a surprising jump. Goodman learned

about the fellowship while serving on the editorial board for

the AAP’s PREP® ICU. A professional medical editor is part of

that team. According to Goodman, at a review session, the

editor complimented her “wordsmithing skills” and mentioned

the Fishbein Fellowship as a possible opportunity to explore

development in that direction. From there, she obtained

letters of recommendation and formally applied for the

position. During her fellowship, Goodman says she spoke with

16 of the former Fishbein Fellows, about two-thirds of whom

remain in the medical editing field.

On a typical day at JAMA, Goodman needed to juggle multiple

assignments. Goodman was the reviewing editor for over 40

submitted manuscripts during her fellowship. She also read

approximately 2-3 dozen submitted papers per week, as

preparation for the weekly manuscript meeting. One of the

former Fishbein fellows described these meetings as “journal

club on steroids” and she certainly found this to be true, with

rigorous evaluation of candidate papers. In the back of the

journal, there are “ Patient Pages” listing Signs/Symptoms,

Diagnosis, Treatment and/or Prevention tips about various

conditions for the lay public, of which Goodman wrote 16 in

the last year. In addition to these assignments and copyediting

responsibilities, Goodman had several additional rotations,

broadening her experience with writing, editing, and

publishing. These included time working with the graphics

department, legal counsel, and with the news section. Her

last rotation entailed reporting on one of the presentations at

the recent professional meeting of the Radiological Society of

North America. Other highlights of her fellowship included

studying publication ethics with JAMA’s Executive Managing

Editor. JAMA has a significant humanities presence, including

art work in each issue. Goodman selected a painting for

inclusion and wrote the accompanying essay.

As a physician working in a journal setting, Goodman noted, “My

clinical experience helped me to contribute to the discussions

we had regarding candidate manuscripts, both in content and

implication. I was able to see how new discoveries might

influence practice, and to place manuscripts in context with

respect to current trends.” Going forward, she hopes to

incorporate some of the skills she learned at JAMA. Goodman

says she particularly enjoyed working with investigators to refine

their question, their analysis, and their interpretation of their

findings – and hopes to get to continue this work here at Lurie

Children’s. “Say someone has a research idea,” Goodman

explains. “I think it always helps to talk to someone who is not

necessarily the content expert but who can review and refine

the study plan. When it is ready for publication, it helps to listen

to the articulation of the words – how it all will look on paper to

someone unfamiliar with the scientific work being done.”

Beyond that, Goodman believes that having someone challenge

ideas at an early stage may result in a better final product.

“Upon leaving the meeting, that person will see problems they

may not have noticed, but they will also have their eyes opened

to new possibilities. They can then go off to review the

literature and make the proposal even better.”

After a week back on the wards, Goodman had a chance to

reflect on her fellowship year: “This experience met and

exceeded every expectation. One of the editors there told me

that it is humbling to work at the journal because thousands of

medical decisions could be made based on what we decide to

publish. I was really struck by this responsibility, and found it

utterly gratifying to work in that environment.” She further

noted that enrichment can often come in surprising ways. “As I

was getting ready to leave to start the fellowship, some of my

colleagues wondered aloud whether it was scary to step away

from the familiarity of patient care for a year. I think that if you

have a passion for something you sometimes have to set that

fear aside and just jump in with both feet. Every new thing you

try helps you grow in insight, reenergizes you, and opens doors

to new opportunities.”

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 2

SPOTLIGHT:

Dr. Denise Goodman Serves as Fishbein Fellow at JAMA

Den

ise M

. Go

od

man

, MD

, MS

Professor of Pedia

trics - Critica

l Care

After 33 years as a member of the

Division of Kidney Diseases at Children's

Memorial Hospital and Lurie Children's

Hospital of Chicago, Dr. Richard A. Cohn

is retiring. For the past 20 years Rick has

served as Medical Director of the Kidney

Transplant Program, consistently ranked in

the top 10 programs in the nation by

transplant number. He has overseen care

for almost 500 transplant patients in their

journeys with their new kidneys.

Rick has been Professor of Pediatrics at

Northwestern University Feinberg School

of Medicine since 2003 and received the A

Todd Davis MD award as Outstanding

Physician in 2006. He was named by Lurie

residents as outstanding teacher in 1989

and again in 2004 and has been listed in

Chicago Magazine among Best Doctors,

Pediatric Nephrology, since 2004.

Dr. Sharon Unti, Residency Program

Director, notes: “Dr. Rick Cohn has

consistently been one of the pediatric

residents’ favorite faculty because of his

enthusiastic dedication to their

education. Dr. Cohn was the faculty

member who originally developed a series

of patient cases used by the residents to

better understand the approach to

pediatric problems from a general pediatric

perspective. This valued learning tool was

expanded throughout the residency

program, and today is incorporated across

all resident rotations as a key monthly

learning conference. His genuine dedication

and constant support were always

appreciated and will always be remembered!

Rick may still occasionally be seen at Lurie

Children’s, as he will be consulting on

outpatients in the near future. Dr. Craig

Langman and the Kidney Diseases

physicians and staff wish Rick and his family

all the best after a long career here.

2013 Master of Sc ience in Cl in ica l Invest igat ion Scholarsh ip Awards

The Clinical Departments of Ann & Robert H. Lurie Children’s Hospital of Chicago and the Ann & Robert H. Lurie Children’s

Hospital of Chicago Research Center recently awarded four scholarships to support tuition for affiliated clinical fellows and

faculty members who are pursuing the Northwestern University Master of Science in Clinical Investigation (MSCI). This is the

fourth cycle of these scholarships. The initiative began in 2010, with the intent of developing the clinical research skills of

trainees and junior faculty members in order to further their careers in academic medicine.

The MSCI Program is sponsored by the Center for Education and Career Development (CECD) of the Northwestern

University Clinical and Translational Sciences (NUCATS) Institute. This program is part-time and consists of evening courses

primarily for medical residents, fellows and junior faculty members who wish to receive formal training in clinical research.

Matriculants actively engage in a research project with a nationally funded Northwestern faculty mentor. Scholarship recipients

begin in the fall and complete the program within two years. Further information on the MSCI Program can be found here.

Leena Bhattacharya, MD Fellow Infectious Diseases Mentors: Ram Yogev, MD; Karen Mestan, MD

“Early Detection of Sepsis in Preterm Infants”

Benjamin Prince, MD Fellow Allergy/Immunology Mentors: Anne Marie Singh, MD; Jacqueline Pongracic, MD

“The Role of T Regulatory Cells in the Development of Tolerance in Food Allergy “

Waheeda Samady, MD Faculty Hospital-Based Medicine Mentor: Jacqueline Pongracic, MD

“Reexamining Maintenance IVF for Hospitalized Pediatric Patients with Gastrointestinal Symptoms”

Sushmita Yallapragada, MD Fellow Neonatology Mentor: Karen Mestan, MD

“Placental Markers of Bronchopulmonary Dysplasia and Pulmonary Hypertension in Extremely Premature Infants”

To contact the Division of

Kidney Diseases, please write:

Ann & Robert H. Lurie

Children’s Hospital of Chicago

225 E. Chicago Avenue #37

Chicago, IL 60611

or call 312.227.6160

Richard A Cohn, MD

Kidney Diseases

ANNOUNCEMENTS: Dr. Richard Cohn (Kidney Diseases) Retires

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 3

Conrad Epting, MD is an Assistant Professor of Pediatrics and

Pathology at Northwestern University Feinberg School of

Medicine and Ann & Robert H. Lurie Children’s Hospital of

Chicago. Epting joined the faculty in the Division of Critical

Care Medicine in October 2007. He completed his

fellowship in Pediatric Critical Care at Children’s Oakland/

University of California Medical Center, San Francisco in

2004. Prior to that, he received his MD from Johns Hopkins

University School of Medicine and completed his residency

training at Denver Children’s Hospital.

Epting found a great fit going into pediatric medicine, noting:

“Who else but pediatricians could appreciate someone with a

Disney personality, who sings Rodgers & Hammerstein songs,

and wants to do teaching rounds at 1:00am?” Regarding his

subspecialty choice, he states, “The ICU environment works

well for me, as I live in the moment, can’t remember

yesterday, and am not organized enough to worry about

tomorrow.” Working in the Intensive Care Unit, he finds it

meaningful to shape the experience for families going through

difficult situations, including the potential loss of a child. He

notes, “Families may quickly forget ‘live-saving heroics,’ but

every detail during a death or withdrawal may become part of

a treasured memory. Guiding them through it gently and

compassionately is a real privilege.”

In his research, Epting is interested in understanding heart

failure and the age-related changes that underlie cardiac

regeneration. His lab specifically seeks to discover new

paradigms in pediatric heart failure at the cellular level. The

lab is also actively researching infectious myocarditis,

particularly Chagas disease, which is the leading cause of heart

failure in Latin America. As Chagas disease is caused by a

parasite, they seek to understand how the parasite can cross

the endothelial cells of the heart, and how it targets the membrane of

ventricular myocytes over other cell types. Several co-authored papers

have thus resulted from collaborations with the Engman laboratory in

parasitology, and more will be emerging soon.

A recipient of a number of awards, Epting was given a pilot award from

the NUCATS Center for Translational Innovation, pilot awards from

the Children’s Hospital of Chicago Research Center, and most recently

the Children’s Heart Foundation Research Award, which invested in the

Epting lab’s work studying age-regulated changes in cardiac stem cells.

With Carl Backer, MD, of the Department of Surgery, Epting developed

the Lurie Heart Center Biorepository Initiative, to enable current and

future research for those interested in congenital and acquired heart

disease. The pursuit of knowledge and the development of trainees’

research careers is a hallmark of Epting’s work. He states, “It brings me

daily pleasure to mentor students and fellows to surpass my own

modest contributions.”

Having been born in Iowa, Epting was pleased to return to the Midwest,

after completing much of his medical training elsewhere. When he

joined the faculty at Northwestern, he found a certain “sense of

familiarity, community, and belonging.” He further notes, “In the

Midwest, you scoop your neighbor’s sidewalk when you do your own.”

Accordingly, he says he feels very much part of the team at Lurie

Children’s, with its spacious, comfortable design and natural sunlight. In

Chicago, he enjoys the public space offered by the lakefront, and the

great nearby restaurants in Streeterville He particularly singles out the

sushi at Friends on Rush, the pan-Asian cuisine at Sunda, lunch at Deca,

and the numerous spots for steak as favorites. Though he doesn’t often

go to movie theatres, Epting is partial to classic Disney and Pixar films,

building rapport with his patients over Ratatouille, The Incredibles, and

others. In his spare time, one is likely to find him in the kitchen, as he

loves to cook and bake. In years past, he was known for bringing a pie

in for each rotation during residency.

FACULTY PROFILE: Conrad Epting, MD (Critical Care)

Epting and family on vacation in Switzerland

Each newsletter features

a faculty member,

to provide insight

into their work

inside the hospital

and their life outside.

Conrad Epting, MD

Critical Care

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 4

ADVOCACY CORNER: 2013 Phys ic ian Advocacy Grant Awards

The Department of Pediatrics Advocacy Board is pleased to announce the 2013

Physician Advocacy Grant awardees. Faculty members from 7 divisions were

awarded funding for their outstanding work. Each of these projects is intended to

improve behavioral, social, economic, or environmental factors for the health of

children and/or adolescents. Please contact Karen Sheehan

([email protected]) if you have questions.

PEDIATRIC GRAND ROUNDS (Updated schedule online)

Aug 2, 2013 Mitochondrial Disorders

Bruce Cohen, MD - Children’s Hospital Medical Center of Akron

Aug 9, 2013 Palliative Care: Forty is the New Twenty

Kelly Michelson, MD - NUFSM/Lurie Children’s

Aug 16, 2013 Giving Feedback is a Two-Way Street

Walter Eppich, MD, MEd - NUFSM/Lurie Children’s

Aug 23, 2013 Project DOCC

Project DOCC Parent Teachers - Lurie Children’s

Aug 30, 2013 Gastroenterology/Hepatology Topic TBA

Ashish Chogle, MBBS - NUFSM/Lurie Children’s

Sept 6, 2013 Endocrinology Topic TBA

Donald Zimmerman, MD - NUFSM/Lurie Children’s

Sept 13, 2013 The Golden Anniversary of Newborn Screening: Lessons & Evolution, as Illustrated by Cystic Fibrosi s

Phillip M. Farrell, MD, PhD - NUFSM/University of Wisconsin

Robert Liem Web-Based Video Education in the Transition Process for

Adolescents and Young Adults with Sickle Cell Disease

Hematology/

Oncology

Joseph DiCara Chicago Youth Programs: Engaging Medical Student & Resident

Advocacy in an Expansion into West Humboldt Park

Hospital-Based

Medicine

Sara Berkelhamer The Helping Babies Survive Program: Evaluation of

Educational Validity

Neonatology

Nguyenvu Nguyen Establishment of a Registry of Pediatric Cardiovascular (CV)

Centers in Low and Middle Income Countries (LMICs)

Cardiac

Intensive Care

Cynthia LaBella Development of Internet-based KIPP (Knee Injury Prevention

Program) training course for Spanish-speaking coaches

Sports

Medicine

Greg Webster Chicagoland Cardiac Connections Cardiology

Wendy Brickman Transitioning from Pediatric to Adult Care: Developing An Endocrine

Associate Chair, Advocacy

Professor, Pediatrics & Preventive Medicine

Click here for the “Salubrity” Advocacy Blog

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 5

Three Department of Pediatrics fellows recently received Children’s Research Foundation grant awards, intended to support basic or

translational research at the fellow level. The 2013 awardees are Mashael Alqahtani, MBBS (Critical Care, Mentor: Conrad Epting,

MD); Ankur Datta, MD (Neonatology, Mentor: Sara Berkelhamer, MD); and Surabhi Batra, MD (Hematology/Oncology, Mentor:

Steven T. Rosen, MD). The three were honored at the Foundation’s annual “Swing into Spring” event in late April. We took a

moment to get more acquainted with Dr. Batra, her research, and her experience to date in the course of her fellowship training at

Lurie Children’s.

As a fellow, one of the initial challenges in choosing a research project is identifying a mentor. Batra says she was pleased to have

connected with Dr. Rosen and gotten to work with his lab. “I initially made contact with Dr. Rosen after reviewing some of the work

his laboratory is doing in metabolism and Cancer. He was very approachable and I connected with him right away. He is an excellent

teacher and a mentor and always inspires me to continue learning with an open and positive mind. He always helps me to develop my

own opportunities and keeps motivating me through setbacks and hurdles. I am truly very thankful to him for all his support and

guidance.“

Batra’s project, “Targeting Glycolysis and Compensatory Mitochondrial Metabolism in Neuroblastoma With FDA

Approved Ritonavir and Metformin” hopes to determine the in vivo efficacy of the HIV protease inhibitor (ritonavir) in combina-

tion with metformin for the treatment of neuroblastoma using a xenograft neuroblastoma model. She tested the dependence of

Neuroblastoma cells on glucose by culturing six different neuroblastoma cell lines under aerobic conditions in the presence and ab-

sence of glucose. These cell lines included both N-myc amplified and non-amplified cell lines. They identified the critical glucose trans-

porters, identifying GLUT 4 as a potential target for intervention, and then cultured cells in the presence of metformin, ritonavir,

both, or neither. They found that GLUT 4 was essential for neuroblastoma cell function and that the presence of metformin and

ritonavir promoted cell death.

So far, results indicate that Neuroblastoma cells are highly dependent on glycolysis for their metabolism and to maintain viability.

Inhibition of glycolysis through the inhibition of glucose flux into the cells using metformin and ritonavir results in cell death. Further

studies to validate this hypothesis and to test in in vivo are underway in the laboratory.

Batra thinks that the relationship between The Robert H. Lurie Comprehensive Cancer Center and Lurie Children’s is developing in a

positive direction, especially given the close proximity. “Lurie Cancer Center offers a wide array of opportunities which can benefit us

at Lurie Children’s to widen our knowledge base and expand our horizons. At the same time, Lurie Children’s has some great re-

sources which can be utilized by the cancer center for various research purposes. Overall there is a scope for many

collaborative projects.” As for the new Lurie Children’s facility, her favorite part is the clinic area on Floor 18, where she sees her

patients. “It is wonderful to see patients interact and socialize with each other and with our wonderful Child Life staff in the waiting

area. The personnel here are all very helpful and truly amazing people!”

On a less formal note, Batra mentions that “Chicago is one of the best cities in the US that I have lived in. The pace of the city is just

about right. It is a perfect blend of a cosmopolitan and comfortable living, combining all of the culture and sophistication with an

affordable lifestyle and down-to-earth character.”

FELLOW

PROFILE:

Surabhi

Batra, MD Hematology/

Oncology

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 6

TECH TIPS: How to properly format your CV for Northwestern…

For Appointments, Promotions or Tenure decisions, all Northwestern University Feinberg School of Medicine faculty

members should format their Curriculum Vitae according to the guidelines established by the Faculty Affairs office.

Maintaining a CV in this format will help minimize delays and confusion in the process of applying for promotion or

tenure. Throughout, education, positions, awards, and other activities should be listed in chronological order, from

earliest to most recent. By following some of the standardized tips below, or using this document as a template, you

can be sure to have a properly formatted document.

In addition, the Faculty Affairs office has many other

online resources, which be helpful in understanding the

policies and procedures for the institution. There is an

online guide to the Promotion and Tenure process, a

listing of policies, a link to the Faculty Handbook, and

more. We encourage you to peruse these materials at

your leisure.

Date of Birth:

Citizenship:

Home Address:

Home Phone:

Business Address:

Business Phone:

Fax:

Email:

Step 1:

List personal details in the prescribed order below.

Step 2:

List Education and Training (in chronological order, ending

with most recent. Include degree, award date, institution,

and discipline.

Step 3:

Continue with the following main headings, in this order:

Licensure/Certification:

Academic Appointments:

Hospital Appointments:

Honors and Awards:

Professional Organizations:

Professional Activities:

Grant Awards:

Invited Lectures:

Publications:

Institutional Service (Committees, Task Forces)

Teaching (Past and Present)

Trainees

Extramural Membership

Editorial Responsibilities

Review Responsibilities

Step 4:

Under “Professional Activities,” please list as follows:

Step 5:

Under “Publications,” please list as follows:

A. Original Investigations

B. Reviews, Case Reports, Letters, Editorials

C. Books and Book Chapters

D. Abstracts

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 7

This annual showcase of clinical and basic research conducted by residents, fellows, graduate students, and research staff was held

on May 16, 2013 Bringing the Hospital and Research Center together, along with other labs and centers throughout the North-

western University community, participants submitted abstracts which were reviewed by faculty members to ensure proper pro-

gress for the level of training. Awards were given to one basic and one clinical project for each year of fellowship training, with

prizes for research staff and others, as deemed fitting.

FIRST YEAR FELLOW BASIC RESEARCH AWARD:

“Expansion of functionally active alloantigen-specific regulatory T cells using activated B cells ”

Scott McEwen, MD, PhD | KIDNEY DISEASES | Mentor: Joseph R. Leventhal MD, PhD

FIRST YEAR FELLOW CLINICAL RESEARCH AWARD:

“Early Detection of Neonatal Sepsis in Preterm Infants ”

Leena Bhattacharya, MD | INFECTIOUS DISEASES | Mentors: Karen Mestan, MD and Ram Yogev, MD

SECOND YEAR FELLOW BASIC RESEARCH AWARD:

“Targeting glycolysis and compensatory mitochondrial metabolism in neuroblastoma with FDA-approved ritonavir and metformin”

Surabhi Batra, MD | HEMATOLOGY, ONCOLOGY | Mentors: Malathy Shanmugam, PhD and Steven T. Rosen, MD

SECOND YEAR FELLOW CLINICAL RESEARCH AWARD:

“The effect of maternal race/ethnicity and weekend birth on induction of labor at 34 weeks' gestation ”

Gustave Falciglia, MD | NEONATOLOGY | Mentor: Karna Murthy, MD, MSc

THIRD YEAR FELLOW BASIC RESEARCH AWARD:

“Novel GCSFR mutation found in patients with SCN, CNL, and AML: a new oncogene”

Taly Glaubach, MD | HEMATOLOGY/ONCOLOGY | Mentor: Seth J Corey, MD/MPH

THIRD YEAR FELLOW CLINICAL RESEARCH AWARD:

“Resident Education in the Era of Work Hour Restriction: a Prospective Observational Study of PICU Bedside Rounds ”

Tara Petersen, MD | CRITICAL CARE | Mentor: Melissa L. Brannen, MD, MEd

POSTDOC RESEARCH AWARD:

“Reduction in microglial activation following experimental traumatic brain injury is associated with greater anxiety

and depression”

Chunshu Piao, PhD | NEUROLOGY & NEUROBIOLOGY PROGRAM

Mentors: Hantamalala Ralay Ranaivo, PhD and Mark S. Wainwright MD, PhD

JUDGES’ AWARD:

“Periostin is Upregulated in the Coronary Arteries of Patients with Kawasaki Disease ”

Rebekah Reindel, MD | INFECTIOUS DISEASES | Mentor: Anne Rowley, MD

JUDGES’ AWARD:

“TRPV1 Mediates Chronic Pain After Murine Urinary Tract Infection ”

John Rosen, MD |GASTROENTEROLOGY, HEPATOLOGY & NUTRITION | Mentor: David Klumpp, PhD

RESEARCH SCHOLARS DAY

2013 WINNERS

R E S E A R C H R E S E A R C H Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 8

R E S E A R C H R E S E A R C H New Awards Received in May 2013

Robert Garofalo, MD

YMAP: Young Men’s Affiliation Project of HIV risk & prevention venue

The University of Texas Houston Health Science Center/NIH subcontract

CVCTPlus: A couples-based approach to linkage to care and ARV adherence

Emory University/NIH subcontract

Stewart Goldman, MD

A phase III, multi-center, open label, randomized, controlled study of the efficacy and

safety of oral LDE225 versus Temozolomide in patients with Hh-pathway activated

relapsed medulloblastoma

Novartis Pharmaceuticals Corporation

Jane Holl, MD

National Children’s Study: Vanguard study (South ROC)

Northwestern University/NIH Subcontract

Marisa Klein-Gitelman, MD

An observational registry of Abatracept in patients with Juvenile Idiopathic Arthritis

Bristol-Myers Squibb Company

Rajesh Kumar, MD

Multi-level understanding of social contributors to SES disparities in Asthma

Northwestern University/NIH subcontract

Susanna McColley, MD

A phase 3 randomized, double blind, placebo-controlled, parallel group study to

evaluate the efficacy and safety of Lumacaftor in combination with Ivacaftor in sub-

jects aged 12 years and older with Cystic Fibrosis

Vertex Pharmaceuticals Incorporated

An ocular safety study of Kalydeco-treated pediatric patients 11 years of age or

younger with Cystic Fibrosis

Vertex Pharmaceuticals Incorporated

Douglas Nordli, MD

Prevention of West syndrome

Citizens United for Research in Epilepsy, Inc.

Jacqueline Pongracic, MD

The PRROTECT (Peanut Reactivity Reduced by Oral Tolerance in an anti-IgE Clinical

Trial) study

Children’s Hospital of Boston/Subcontract

Alexis Thompson, MD

A phase 3 study for the efficacy and safety comparison of Prasugrel and placebo in

pediatric patients with Sickle Cell Disease H7T-MC-TADO

Eli Lilly and Company

Jacek Topczewski, PhD

Identification of a gene involved in late stages of zebrafish craniofacial development

(NRSA pre-doctoral fellowship for Rebecca Anderson)

National Institute of Dental and Craniofacial Research

Sharon Unti, MD

Multi-center trial of limiting PGY 2 and 3 resident work hours in ICU patient safety

Brigham & Women’s Hospital/NIH subcontracts

Donald Zimmerman, MD

Travel grant application for PES 2013

Pediatric Endocrine Society

New Awards Received in June2013

Adam Becker, PhD

CPS Summer Bridge Curriculum

Chicago Public Schools

Anne Berg, PhD

Pediatric Epilepsy Research Consortium (PERC): Early Onset Epilepsy Consortium

(EOEC) infrastructure grant

Pediatric Epilepsy Research Foundation

Ellen Brooks, PhD

Prognostic biomarkers to predict progression of pediatric chronic kidney disease

National Institute of Child Health and Human Development

Barbara Burton, MD

A multicenter, open-label BMN 110 US Expanded Access Program (BMN 110 US EAP)

to provide BMN 110 to patients diagnosed with MPS IVA

BioMarin Pharmaceutical Inc.

Raye-Ann DeRegnier, MD

NICHD Maternal Fetal Medicine Units Network: A randomized trial of Thyroxine thera-

py for subclinical hypothyroidism or hypothyroxinemia diagnosed during pregnancy

Northwestern University/NIH subcontract

Christine DiDonato, PhD

Spina Muscular Atrophy: inducing SMN expression

National Institute of Neurological Disorders and Stroke

Stewart Goldman, MD

Children’s Oncology Group Phase 1/Pilot Consortium

Children’s Hospital of Philadelphia/NIH subcontract

Rajesh Kumar, MD

Choriamnionitis and Methylation in Asthma Disparities (CMAD) study

American Academy of Allergy, Asthma & Immunology

John Millichap, MD

Rational Intervention for KCNQ2 Epileptic Encephalopathy (RIKEE) Network

Baylor College of Medicine/Subcontract

Douglas Nordli, MD

Consequences of prolonged febrile seizures in childhood

Albert Einstein College of Medicine/NIH subcontract

M. Bento Soares, PhD

Radial glia-specific nanoplatforms for in vivo non-invasive diagnostic imaging of neural

stem cells

Northwestern University

Simone Sredni, MD, PhD

Avoiding unnecessary toxicity and improving survival of children with low grade gliomas

Voices Against Brain Cancer

Jacek Topczewski, PhD

Pilot experiment for AbbVie

AbbVie, Inc.

Ram Yogev, MD

A phase 1, open label, single dose study to investigate the pharmacokinetics, safety and

tolerability of Dalbavancin in hospitalized children aged 3 months to 11 years receiving

standard intravenous anti-infective treatment for Bacter

Duke University/Subcontract

FROM THE OFFICE OF SPONSORED PROGRAMS — New Awards

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 9

Emalee Flaherty , MD Marisa Klein-Gitelman, MD, MPH Cynthia Mears, DO Mary Clyde Pierce, MD Professor Professor Professor Professor Academic General Pediatrics Rheumatology Community-Based Primary Care Emergency Medicine

Christine diDonato, PhD Craig Garfield, MD Jolanta Topczewska, PhD Karen Mestan, MD Associate Professor (with tenure) Associate Professor Associate Professor (Research) Associate Professor Human Molecular Genetics Hospital-Based Medicine Developmental Biology Neonatology

Mary Nevin, MD Alan Rosenblatt , MD Julie Stamos, MD Associate Professor Associate Professor (Clinical) Associate Professor

Pulmonary Medicine Community-Based Primary Care Infectious Diseases

FACULTY PROMOTIONS ANNOUNCEMENT

We are delighted to announce the faculty promotions that have been approved by Northwestern University, effective

September 1, 2013. For these individuals, consideration of their promotions started over a year ago. Each was evaluated

by the Department Appointment, Promotions, and Tenure (APT) Committee, one or more medical school committees,

multiple outside referees, Dean Neilson, and, ultimately, Provost Linzer. The elaborate steps and great care involved in

this process are a reflection of the importance that the university ascribes to a positive decision for promotion. These

faculty have made outstanding contributions to the mission of the university and have distinguished themselves and their

institutions in their work.

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 10

Rachel Robison, MD Suzanne M Schmidt, MD Assistant Professor Assistant Professor Allergy/Immunology Emergency Medicine

Robert Greenberg Melanie Makhija Deepa Nair Srishti Nangia Assistant Professor Assistant Professor Assistant Professor Assistant Professor Hospital-Based Medicine Allergy/Immunology Emergency Medicine Neurology

Ashish Chogle, MBBS Leslie Cordes Christopher Donohoe Naomi Fogel

Assistant Professor Assistant Professor (Clinical) Assistant Professor (Clinical) Assistant Professor Gastroenterology/Hepatology/Nutrition Community-Based Primary Care Community-Based Primary Care Endocrinology

Not pictured:

Marta Perez

Assistant Professor (Neonatology)

Parag Shah

Assistant Professor (Hospital-Based Medicine)

Angkana Roy

Assistant Professor (Clinical)

FACULTY PROMOTIONS ANNOUNCEMENT

July 15, 2013 Two Pediatrics Faculty Members Receive Searle Teaching Fellowships

July 3, 2013 Ruchi Gupta, MD, MPH Discusses New Study Linking Antibiotics to Eczema

June 28, 2013 Cynthia LaBella, MD Notes Changes in Cheerleading May Lead to More Injuries

June 26, 2013 Fellow Reeti Chawla, MD Presents on Genetics and Newborn Adiposity at National Meeting

June 12, 2013 Sookyong Koh, MD, PhD Contributes to New Therapy for Febrile Seizures in Children

May 20, 2013 Leon Epstein, MD Investigates Link Between Circadian Rhythms, Colic, and Migraines

NE W S H IG H L IG H TS : Faculty Research, Ref lect ions , & More in the Media

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 11

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 12

NEW FACULTY MEMBERS

We often welcome a bumper crop of new faculty members in the summer, and this year is no exception.

Between the beginning of July and the middle of August 2013, sixteen new physicians will be joining our

department faculty. Several recent graduates of our pediatric residency program have stayed on as

hospitalists, designated with an asterisk below. Others come to us from equally esteemed positions from

across the country. The Department of Pediatrics Faculty Affairs Board (FAB) will be sponsoring a

meet-and-greet event onsite at Lurie Children’s later this summer. Details for this event will be

forthcoming. Meanwhile, please extend your greetings to these new colleagues.

07/01/2013 Zarina Dohadwala, MD * Hospital-Based Medicine Lurie/Prentice

07/01/2013 James Felker, MD * Hospital-Based Medicine Lurie/Prentice

07/01/2013 Christine Higham, MD * Hospital-Based Medicine Lurie/Prentice

07/01/2013 Kiley Johnson, MD * Hospital-Based Medicine Lurie/Prentice

07/01/2013 Irini Kolaitis, MD * Hospital-Based Medicine Lurie/Prentice

07/01/2013 Alina Lopez, MD * Hospital-Based Medicine Lurie/Prentice

07/01/2013 Melisa Nassin, MD Hospital-Based Medicine Lurie/Prentice Recently completed residency at Boston Children’s Hospital and Boston Medical Center 07/01/2013 Kirsten Rose-Felker, MD * Hospital-Based Medicine Lurie

07/01/2013 Courtney Weems, MD Hospital-Based Medicine Lurie/LaRabida Recently completed residency at University of Chicago 07/01/2013 Jacqueline Winikoff Wallis, MD * Hospital-Based Medicine Lurie/Prentice

07/12/2013 Kavita Hodgkins, MD Kidney Diseases Lurie/Prentice

07/15/2013 Mahima Keswani, MD Kidney Diseases Lurie/Prentice Most recently Attending and Assistant Professor (Clinical) joining from Children’s National Medical Center 08/01/2013 Mjaye Mazwi, MD Cardiology Recently completed fellowships in Cardiology and Critical Care/Anesthesia at Boston Children’s Hospital

08/01/2013 Lauren Marsilio MD Critical Care Medicine Recently completed fellowship in Critical Care at Children’s Hospital of Philadelphia 08/01/2013 Zachary Pittsenbarger, MD Emergency Medicine Recently completed fellowship and chief fellow year in Emergency Medicine at Boston Children’s Hospital

08/01/2013 Patrick Myers, MD Neonatology Completed fellowship in Neonatology and served as Clinical Neonatology Associate at University of Chicago

(from L to R)

Zarina Dohadwala, MD

James Felker, MD

Christine Higham, MD

Kavita Hodgkins, MD

Kiley Johnson, MD

Irini Kolaitis, MD

Alina Lopez, MD

Zachary Pittsenbarger, MD

Kirsten Rose-Felker, MD

Courtney Weems, MD

Jacqueline Winikoff-Wallis, MD

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 13

McGaw Medical Center of Northwestern University

Department of Pediatrics | New Fellows, July 2013

Yuemi An-Grogan, MD

Emergency Medicine

Seema Bansal, MD

Clinical Neurophysiology

Jillian Bybee, MD

Critical Care Medicine

Joseph Casadonte, MD

Cardiology

Christina Cochran, MD

Emergency Medicine

James Feinstein, MD, MPH

Academic General Pediatrics

Rebecca Garcia-Sosa, MD

Child Neurology

Tracy Gertler, MD

Child Neurology

Katherine Gregersen, DO

Critical Care Medicine

Barry Pelz, MD

Allergy/Immunology

Tyler Harris, MD

Cardiology

Karla Wehrheim, MD

Cardiology

Luda Sorin, MD

Clinical Neurophysiology

Vishal Gunnala, MD

Critical Care Medicine

Astha Sharma, MD

Critical Care Medicine

Adnan Mir, MD, PhD

Dermatology

Rachel Kadakia, MD

Endocrinology

Chantal Lucia-Casadonte, MD

Gastroenterology/Hepatology

Michael Malandra, MD

Gastroenterology/Hepatology

Prev. Position: Asst. Professor,

University of Colorado Denver

Prev. Position: Pediatrics Resident,

NUFSM/Lurie Children’s

Prev. Position: Pediatrics Resident,

University of Chicago

Prev. Position: Pediatrics Resident,

NUFSM/Lurie Children’s

Prev. Position: Pediatrics Resident,

NUFSM/Lurie Children’s

Prev. Position: Pediatrics Resident,

NUFSM/Lurie Children’s

Prev. Position: Pediatrics Resident,

Miami Children’s Hospital

Prev. Position: Child Neuro Resident,

Children's National Medical Center

Prev. Position: Child Neuro Resident,

Loma Linda University

Prev. Position: Pediatrics Resident,

Phoenix Children’s Hospital

Prev. Position: Pediatrics Resident,

University of Connecticut

Prev. Position: Med/Peds Resident,

Loyola University

Prev. Position: Pediatrics Resident,

SUNY Upstate—Syracuse

Prev. Position: Dermatology Resident,

NYU School of Medicine

Prev. Position: Research Fellow,

Northwestern Memorial Hospital

Prev. Position: Pediatrics Resident,

Medical University of South Carolina

Prev. Position: Pediatrics Resident,

NUFSM/Lurie Children’s

Prev. Position: Pediatrics Resident,

Miami Children’s Hospital

Prev. Position: Pediatrics Resident,

University of Tennessee

Lacey Kruse, MD

Dermatology

Prev. Position: Dermatology Resident,

Southern Illinois University

Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 14

McGaw Medical Center of Northwestern University

Department of Pediatrics | New Fellows, July 2013

Matthew Abts, MD

Pulmonary Medicine

Sherif Badawy, MD

Hematology/Oncology

Rakhee Bowker, MD

Neonatology

Larisa Broglie, MD

Hematology/Oncology

Eileen Broomall, MD

Neurocritical Care

Amy Feldman, MD

Hepatology/Transplant

Marielle Fricchione, MD

Infectious Diseases

Paul Lee, MD, PhD

Hematology/Oncology

Mina Kim, MD

Kidney Diseases

Shayna Hibbs, MD

Neonatology

Grace Lin MD

Neonatology

Vamshi Rao, MD

Neuromuscular Medicine

Natasha Pillay Smiley, MD

Neurooncology

Sarah Kinsella, MD

Sports Medicine

Pallavi Patwari, MD

Sleep Medicine

The Department of Pediatrics fellowship programs have grown significantly in

recent years, from 60 positions in 2003-2004 to 85 positions in 2013-2014.

Many of these additional fellows are in newer subspecialties, like Sleep Medicine

and Child Abuse Pediatrics, or in advanced programs, such as Neurocritical

Care and Neuromuscular Medicine.

If you are a graduate of one of our fellowships, we encourage you to keep in

touch with us. Please send updated information on your current position and

contact details to [email protected].

Prev. Position: Pediatrics Resident

Mount Sinai Medical Center

Prev. Position: Pediatrics Resident,

NUFSM/Lurie Children’s

Prev. Position: Peds GI Fellow,

Children’s Hospital of Colorado

Prev. Position: Pediatrics Resident,

Rush University Medical Center

Prev. Position: Pediatrics Resident,

University of Chicago

Prev. Position: Pediatrics Resident

University of Iowa

Prev. Position: Pediatrics Resident,

Columbia University

Prev. Position: Pediatrics Resident,

New York University

Prev. Position: Pediatrics Resident,

NUFSM/Lurie Children’s

Prev. Position: Child Neurology

Mayo Clinic

Prev. Position: Child Neuro Resident,

NUFSM/Lurie Children’s

Prev. Position: Pediatrics Resident,

NUFSM/Lurie Children’s

Prev. Position: Heme/Onc Fellow,

Nationwide Children’s Hospital

Prev. Position: Pediatrics Resident,

NUFSM/Lurie Children’s

Prev. Position: Attending, Center for

Autonomic Medicine, NUFSM