department newsletter july 2013 - northwestern … epting, md is an assistant professor of...
TRANSCRIPT
Healthcare reform is here and will inevitably change the way medicine is
practiced. Care for patients will be centered in their medical homes and coordinated by
primary care physicians. Efficiencies together with the focus on measurable outcomes
will improve the health of our communities and lower the overall cost of health
care. Leaders of our Divisions, the Department, and Lurie Children’s have been
working to prepare us for these changes, including working in more formal partnerships
with our primary care physicians (Clinically Integrated Network) and the State of Illinois
(Coordinated Care Entity).
At the same time, we are committed to the growth and development of our clinical,
education, and research programs. National searches are underway, seeking
outstanding clinical and academic leaders for our Divisions of Neonatology and
Hematology/Oncology/Stem Cell Transplantation and a leader for Clinical and
Translational Research. Another search will soon be organized for a Division Head of
Academic General Pediatrics. Reflective of the growth of our Department and our
services, several new divisions have been organized and new division heads
appointed. These are:
Division of Hospital-based Medicine (Lurie Children’s): Robert Greenberg
Division of Hospital-based Medicine (Outreach): Patricia Chiamas
Division of Adolescent Medicine: Robert Garofalo
Division of Child Abuse Pediatrics: Emalee Flaherty
Division of Behavior/Development: Dana Brazdziunas
Again, I hope you enjoy the contents of this publication. Should you have ideas for
submissions going forward, please contact our Department Communications Associate,
Brian von Rueden, at: [email protected]. Thank you for your ongoing
work on behalf of our patients and families, and for your commitment to this department.
CHAIRMAN’S UPDATE : Thomas P. Green, MD
Depar tment Newsletter July 2013
Volume 1, Issue 3
Department of
Pediatrics
Northwestern University
Feinberg School of Medicine
Ann & Robert H. Lurie
Children’s Hospital of Chicago
Children’s Hospital of Chicago
Research Center
Phone: 312.227.3210
Fax: 312.227.9637
Email: [email protected]
The Department of
Pediatrics of Northwestern
University Feinberg School
of Medicine is dedicated
to understanding and
promoting optimal child
health and function.
Established in 1883, The Journal of the American Medical
Association (or JAMA) is one of the premier peer-edited medical
journals, released on a weekly basis. From July 2012 through
June 2013, Denise M. Goodman, Professor of Pediatrics
(Critical Care), served as the 31st Morris Fishbein Fellow in
Medical Editing at JAMA. The position involves working with
senior editorial leadership, while receiving intensive immersive
instruction in study design, analysis, and interpretation. When
articles are submitted for potential publication, they are
assigned to reviewing editors who meticulously evaluate them
and decide whether they will be sent out for peer review. If
they pass the initial step, they may still be rejected or presented
at a manuscript meeting, a twice-weekly session where the
senior and associate editors further discuss papers, evaluating
the novelty, validity, and implications of the manuscript.
For a physician normally involved with many clinical
responsibilities in the fast-paced ICU, a position focused on
literature may seem like a surprising jump. Goodman learned
about the fellowship while serving on the editorial board for
the AAP’s PREP® ICU. A professional medical editor is part of
that team. According to Goodman, at a review session, the
editor complimented her “wordsmithing skills” and mentioned
the Fishbein Fellowship as a possible opportunity to explore
development in that direction. From there, she obtained
letters of recommendation and formally applied for the
position. During her fellowship, Goodman says she spoke with
16 of the former Fishbein Fellows, about two-thirds of whom
remain in the medical editing field.
On a typical day at JAMA, Goodman needed to juggle multiple
assignments. Goodman was the reviewing editor for over 40
submitted manuscripts during her fellowship. She also read
approximately 2-3 dozen submitted papers per week, as
preparation for the weekly manuscript meeting. One of the
former Fishbein fellows described these meetings as “journal
club on steroids” and she certainly found this to be true, with
rigorous evaluation of candidate papers. In the back of the
journal, there are “ Patient Pages” listing Signs/Symptoms,
Diagnosis, Treatment and/or Prevention tips about various
conditions for the lay public, of which Goodman wrote 16 in
the last year. In addition to these assignments and copyediting
responsibilities, Goodman had several additional rotations,
broadening her experience with writing, editing, and
publishing. These included time working with the graphics
department, legal counsel, and with the news section. Her
last rotation entailed reporting on one of the presentations at
the recent professional meeting of the Radiological Society of
North America. Other highlights of her fellowship included
studying publication ethics with JAMA’s Executive Managing
Editor. JAMA has a significant humanities presence, including
art work in each issue. Goodman selected a painting for
inclusion and wrote the accompanying essay.
As a physician working in a journal setting, Goodman noted, “My
clinical experience helped me to contribute to the discussions
we had regarding candidate manuscripts, both in content and
implication. I was able to see how new discoveries might
influence practice, and to place manuscripts in context with
respect to current trends.” Going forward, she hopes to
incorporate some of the skills she learned at JAMA. Goodman
says she particularly enjoyed working with investigators to refine
their question, their analysis, and their interpretation of their
findings – and hopes to get to continue this work here at Lurie
Children’s. “Say someone has a research idea,” Goodman
explains. “I think it always helps to talk to someone who is not
necessarily the content expert but who can review and refine
the study plan. When it is ready for publication, it helps to listen
to the articulation of the words – how it all will look on paper to
someone unfamiliar with the scientific work being done.”
Beyond that, Goodman believes that having someone challenge
ideas at an early stage may result in a better final product.
“Upon leaving the meeting, that person will see problems they
may not have noticed, but they will also have their eyes opened
to new possibilities. They can then go off to review the
literature and make the proposal even better.”
After a week back on the wards, Goodman had a chance to
reflect on her fellowship year: “This experience met and
exceeded every expectation. One of the editors there told me
that it is humbling to work at the journal because thousands of
medical decisions could be made based on what we decide to
publish. I was really struck by this responsibility, and found it
utterly gratifying to work in that environment.” She further
noted that enrichment can often come in surprising ways. “As I
was getting ready to leave to start the fellowship, some of my
colleagues wondered aloud whether it was scary to step away
from the familiarity of patient care for a year. I think that if you
have a passion for something you sometimes have to set that
fear aside and just jump in with both feet. Every new thing you
try helps you grow in insight, reenergizes you, and opens doors
to new opportunities.”
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 2
SPOTLIGHT:
Dr. Denise Goodman Serves as Fishbein Fellow at JAMA
Den
ise M
. Go
od
man
, MD
, MS
Professor of Pedia
trics - Critica
l Care
After 33 years as a member of the
Division of Kidney Diseases at Children's
Memorial Hospital and Lurie Children's
Hospital of Chicago, Dr. Richard A. Cohn
is retiring. For the past 20 years Rick has
served as Medical Director of the Kidney
Transplant Program, consistently ranked in
the top 10 programs in the nation by
transplant number. He has overseen care
for almost 500 transplant patients in their
journeys with their new kidneys.
Rick has been Professor of Pediatrics at
Northwestern University Feinberg School
of Medicine since 2003 and received the A
Todd Davis MD award as Outstanding
Physician in 2006. He was named by Lurie
residents as outstanding teacher in 1989
and again in 2004 and has been listed in
Chicago Magazine among Best Doctors,
Pediatric Nephrology, since 2004.
Dr. Sharon Unti, Residency Program
Director, notes: “Dr. Rick Cohn has
consistently been one of the pediatric
residents’ favorite faculty because of his
enthusiastic dedication to their
education. Dr. Cohn was the faculty
member who originally developed a series
of patient cases used by the residents to
better understand the approach to
pediatric problems from a general pediatric
perspective. This valued learning tool was
expanded throughout the residency
program, and today is incorporated across
all resident rotations as a key monthly
learning conference. His genuine dedication
and constant support were always
appreciated and will always be remembered!
Rick may still occasionally be seen at Lurie
Children’s, as he will be consulting on
outpatients in the near future. Dr. Craig
Langman and the Kidney Diseases
physicians and staff wish Rick and his family
all the best after a long career here.
2013 Master of Sc ience in Cl in ica l Invest igat ion Scholarsh ip Awards
The Clinical Departments of Ann & Robert H. Lurie Children’s Hospital of Chicago and the Ann & Robert H. Lurie Children’s
Hospital of Chicago Research Center recently awarded four scholarships to support tuition for affiliated clinical fellows and
faculty members who are pursuing the Northwestern University Master of Science in Clinical Investigation (MSCI). This is the
fourth cycle of these scholarships. The initiative began in 2010, with the intent of developing the clinical research skills of
trainees and junior faculty members in order to further their careers in academic medicine.
The MSCI Program is sponsored by the Center for Education and Career Development (CECD) of the Northwestern
University Clinical and Translational Sciences (NUCATS) Institute. This program is part-time and consists of evening courses
primarily for medical residents, fellows and junior faculty members who wish to receive formal training in clinical research.
Matriculants actively engage in a research project with a nationally funded Northwestern faculty mentor. Scholarship recipients
begin in the fall and complete the program within two years. Further information on the MSCI Program can be found here.
Leena Bhattacharya, MD Fellow Infectious Diseases Mentors: Ram Yogev, MD; Karen Mestan, MD
“Early Detection of Sepsis in Preterm Infants”
Benjamin Prince, MD Fellow Allergy/Immunology Mentors: Anne Marie Singh, MD; Jacqueline Pongracic, MD
“The Role of T Regulatory Cells in the Development of Tolerance in Food Allergy “
Waheeda Samady, MD Faculty Hospital-Based Medicine Mentor: Jacqueline Pongracic, MD
“Reexamining Maintenance IVF for Hospitalized Pediatric Patients with Gastrointestinal Symptoms”
Sushmita Yallapragada, MD Fellow Neonatology Mentor: Karen Mestan, MD
“Placental Markers of Bronchopulmonary Dysplasia and Pulmonary Hypertension in Extremely Premature Infants”
To contact the Division of
Kidney Diseases, please write:
Ann & Robert H. Lurie
Children’s Hospital of Chicago
225 E. Chicago Avenue #37
Chicago, IL 60611
or call 312.227.6160
Richard A Cohn, MD
Kidney Diseases
ANNOUNCEMENTS: Dr. Richard Cohn (Kidney Diseases) Retires
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 3
Conrad Epting, MD is an Assistant Professor of Pediatrics and
Pathology at Northwestern University Feinberg School of
Medicine and Ann & Robert H. Lurie Children’s Hospital of
Chicago. Epting joined the faculty in the Division of Critical
Care Medicine in October 2007. He completed his
fellowship in Pediatric Critical Care at Children’s Oakland/
University of California Medical Center, San Francisco in
2004. Prior to that, he received his MD from Johns Hopkins
University School of Medicine and completed his residency
training at Denver Children’s Hospital.
Epting found a great fit going into pediatric medicine, noting:
“Who else but pediatricians could appreciate someone with a
Disney personality, who sings Rodgers & Hammerstein songs,
and wants to do teaching rounds at 1:00am?” Regarding his
subspecialty choice, he states, “The ICU environment works
well for me, as I live in the moment, can’t remember
yesterday, and am not organized enough to worry about
tomorrow.” Working in the Intensive Care Unit, he finds it
meaningful to shape the experience for families going through
difficult situations, including the potential loss of a child. He
notes, “Families may quickly forget ‘live-saving heroics,’ but
every detail during a death or withdrawal may become part of
a treasured memory. Guiding them through it gently and
compassionately is a real privilege.”
In his research, Epting is interested in understanding heart
failure and the age-related changes that underlie cardiac
regeneration. His lab specifically seeks to discover new
paradigms in pediatric heart failure at the cellular level. The
lab is also actively researching infectious myocarditis,
particularly Chagas disease, which is the leading cause of heart
failure in Latin America. As Chagas disease is caused by a
parasite, they seek to understand how the parasite can cross
the endothelial cells of the heart, and how it targets the membrane of
ventricular myocytes over other cell types. Several co-authored papers
have thus resulted from collaborations with the Engman laboratory in
parasitology, and more will be emerging soon.
A recipient of a number of awards, Epting was given a pilot award from
the NUCATS Center for Translational Innovation, pilot awards from
the Children’s Hospital of Chicago Research Center, and most recently
the Children’s Heart Foundation Research Award, which invested in the
Epting lab’s work studying age-regulated changes in cardiac stem cells.
With Carl Backer, MD, of the Department of Surgery, Epting developed
the Lurie Heart Center Biorepository Initiative, to enable current and
future research for those interested in congenital and acquired heart
disease. The pursuit of knowledge and the development of trainees’
research careers is a hallmark of Epting’s work. He states, “It brings me
daily pleasure to mentor students and fellows to surpass my own
modest contributions.”
Having been born in Iowa, Epting was pleased to return to the Midwest,
after completing much of his medical training elsewhere. When he
joined the faculty at Northwestern, he found a certain “sense of
familiarity, community, and belonging.” He further notes, “In the
Midwest, you scoop your neighbor’s sidewalk when you do your own.”
Accordingly, he says he feels very much part of the team at Lurie
Children’s, with its spacious, comfortable design and natural sunlight. In
Chicago, he enjoys the public space offered by the lakefront, and the
great nearby restaurants in Streeterville He particularly singles out the
sushi at Friends on Rush, the pan-Asian cuisine at Sunda, lunch at Deca,
and the numerous spots for steak as favorites. Though he doesn’t often
go to movie theatres, Epting is partial to classic Disney and Pixar films,
building rapport with his patients over Ratatouille, The Incredibles, and
others. In his spare time, one is likely to find him in the kitchen, as he
loves to cook and bake. In years past, he was known for bringing a pie
in for each rotation during residency.
FACULTY PROFILE: Conrad Epting, MD (Critical Care)
Epting and family on vacation in Switzerland
Each newsletter features
a faculty member,
to provide insight
into their work
inside the hospital
and their life outside.
Conrad Epting, MD
Critical Care
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 4
ADVOCACY CORNER: 2013 Phys ic ian Advocacy Grant Awards
The Department of Pediatrics Advocacy Board is pleased to announce the 2013
Physician Advocacy Grant awardees. Faculty members from 7 divisions were
awarded funding for their outstanding work. Each of these projects is intended to
improve behavioral, social, economic, or environmental factors for the health of
children and/or adolescents. Please contact Karen Sheehan
([email protected]) if you have questions.
PEDIATRIC GRAND ROUNDS (Updated schedule online)
Aug 2, 2013 Mitochondrial Disorders
Bruce Cohen, MD - Children’s Hospital Medical Center of Akron
Aug 9, 2013 Palliative Care: Forty is the New Twenty
Kelly Michelson, MD - NUFSM/Lurie Children’s
Aug 16, 2013 Giving Feedback is a Two-Way Street
Walter Eppich, MD, MEd - NUFSM/Lurie Children’s
Aug 23, 2013 Project DOCC
Project DOCC Parent Teachers - Lurie Children’s
Aug 30, 2013 Gastroenterology/Hepatology Topic TBA
Ashish Chogle, MBBS - NUFSM/Lurie Children’s
Sept 6, 2013 Endocrinology Topic TBA
Donald Zimmerman, MD - NUFSM/Lurie Children’s
Sept 13, 2013 The Golden Anniversary of Newborn Screening: Lessons & Evolution, as Illustrated by Cystic Fibrosi s
Phillip M. Farrell, MD, PhD - NUFSM/University of Wisconsin
Robert Liem Web-Based Video Education in the Transition Process for
Adolescents and Young Adults with Sickle Cell Disease
Hematology/
Oncology
Joseph DiCara Chicago Youth Programs: Engaging Medical Student & Resident
Advocacy in an Expansion into West Humboldt Park
Hospital-Based
Medicine
Sara Berkelhamer The Helping Babies Survive Program: Evaluation of
Educational Validity
Neonatology
Nguyenvu Nguyen Establishment of a Registry of Pediatric Cardiovascular (CV)
Centers in Low and Middle Income Countries (LMICs)
Cardiac
Intensive Care
Cynthia LaBella Development of Internet-based KIPP (Knee Injury Prevention
Program) training course for Spanish-speaking coaches
Sports
Medicine
Greg Webster Chicagoland Cardiac Connections Cardiology
Wendy Brickman Transitioning from Pediatric to Adult Care: Developing An Endocrine
Associate Chair, Advocacy
Professor, Pediatrics & Preventive Medicine
Click here for the “Salubrity” Advocacy Blog
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 5
Three Department of Pediatrics fellows recently received Children’s Research Foundation grant awards, intended to support basic or
translational research at the fellow level. The 2013 awardees are Mashael Alqahtani, MBBS (Critical Care, Mentor: Conrad Epting,
MD); Ankur Datta, MD (Neonatology, Mentor: Sara Berkelhamer, MD); and Surabhi Batra, MD (Hematology/Oncology, Mentor:
Steven T. Rosen, MD). The three were honored at the Foundation’s annual “Swing into Spring” event in late April. We took a
moment to get more acquainted with Dr. Batra, her research, and her experience to date in the course of her fellowship training at
Lurie Children’s.
As a fellow, one of the initial challenges in choosing a research project is identifying a mentor. Batra says she was pleased to have
connected with Dr. Rosen and gotten to work with his lab. “I initially made contact with Dr. Rosen after reviewing some of the work
his laboratory is doing in metabolism and Cancer. He was very approachable and I connected with him right away. He is an excellent
teacher and a mentor and always inspires me to continue learning with an open and positive mind. He always helps me to develop my
own opportunities and keeps motivating me through setbacks and hurdles. I am truly very thankful to him for all his support and
guidance.“
Batra’s project, “Targeting Glycolysis and Compensatory Mitochondrial Metabolism in Neuroblastoma With FDA
Approved Ritonavir and Metformin” hopes to determine the in vivo efficacy of the HIV protease inhibitor (ritonavir) in combina-
tion with metformin for the treatment of neuroblastoma using a xenograft neuroblastoma model. She tested the dependence of
Neuroblastoma cells on glucose by culturing six different neuroblastoma cell lines under aerobic conditions in the presence and ab-
sence of glucose. These cell lines included both N-myc amplified and non-amplified cell lines. They identified the critical glucose trans-
porters, identifying GLUT 4 as a potential target for intervention, and then cultured cells in the presence of metformin, ritonavir,
both, or neither. They found that GLUT 4 was essential for neuroblastoma cell function and that the presence of metformin and
ritonavir promoted cell death.
So far, results indicate that Neuroblastoma cells are highly dependent on glycolysis for their metabolism and to maintain viability.
Inhibition of glycolysis through the inhibition of glucose flux into the cells using metformin and ritonavir results in cell death. Further
studies to validate this hypothesis and to test in in vivo are underway in the laboratory.
Batra thinks that the relationship between The Robert H. Lurie Comprehensive Cancer Center and Lurie Children’s is developing in a
positive direction, especially given the close proximity. “Lurie Cancer Center offers a wide array of opportunities which can benefit us
at Lurie Children’s to widen our knowledge base and expand our horizons. At the same time, Lurie Children’s has some great re-
sources which can be utilized by the cancer center for various research purposes. Overall there is a scope for many
collaborative projects.” As for the new Lurie Children’s facility, her favorite part is the clinic area on Floor 18, where she sees her
patients. “It is wonderful to see patients interact and socialize with each other and with our wonderful Child Life staff in the waiting
area. The personnel here are all very helpful and truly amazing people!”
On a less formal note, Batra mentions that “Chicago is one of the best cities in the US that I have lived in. The pace of the city is just
about right. It is a perfect blend of a cosmopolitan and comfortable living, combining all of the culture and sophistication with an
affordable lifestyle and down-to-earth character.”
FELLOW
PROFILE:
Surabhi
Batra, MD Hematology/
Oncology
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 6
TECH TIPS: How to properly format your CV for Northwestern…
For Appointments, Promotions or Tenure decisions, all Northwestern University Feinberg School of Medicine faculty
members should format their Curriculum Vitae according to the guidelines established by the Faculty Affairs office.
Maintaining a CV in this format will help minimize delays and confusion in the process of applying for promotion or
tenure. Throughout, education, positions, awards, and other activities should be listed in chronological order, from
earliest to most recent. By following some of the standardized tips below, or using this document as a template, you
can be sure to have a properly formatted document.
In addition, the Faculty Affairs office has many other
online resources, which be helpful in understanding the
policies and procedures for the institution. There is an
online guide to the Promotion and Tenure process, a
listing of policies, a link to the Faculty Handbook, and
more. We encourage you to peruse these materials at
your leisure.
Date of Birth:
Citizenship:
Home Address:
Home Phone:
Business Address:
Business Phone:
Fax:
Email:
Step 1:
List personal details in the prescribed order below.
Step 2:
List Education and Training (in chronological order, ending
with most recent. Include degree, award date, institution,
and discipline.
Step 3:
Continue with the following main headings, in this order:
Licensure/Certification:
Academic Appointments:
Hospital Appointments:
Honors and Awards:
Professional Organizations:
Professional Activities:
Grant Awards:
Invited Lectures:
Publications:
Institutional Service (Committees, Task Forces)
Teaching (Past and Present)
Trainees
Extramural Membership
Editorial Responsibilities
Review Responsibilities
Step 4:
Under “Professional Activities,” please list as follows:
Step 5:
Under “Publications,” please list as follows:
A. Original Investigations
B. Reviews, Case Reports, Letters, Editorials
C. Books and Book Chapters
D. Abstracts
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 7
This annual showcase of clinical and basic research conducted by residents, fellows, graduate students, and research staff was held
on May 16, 2013 Bringing the Hospital and Research Center together, along with other labs and centers throughout the North-
western University community, participants submitted abstracts which were reviewed by faculty members to ensure proper pro-
gress for the level of training. Awards were given to one basic and one clinical project for each year of fellowship training, with
prizes for research staff and others, as deemed fitting.
FIRST YEAR FELLOW BASIC RESEARCH AWARD:
“Expansion of functionally active alloantigen-specific regulatory T cells using activated B cells ”
Scott McEwen, MD, PhD | KIDNEY DISEASES | Mentor: Joseph R. Leventhal MD, PhD
FIRST YEAR FELLOW CLINICAL RESEARCH AWARD:
“Early Detection of Neonatal Sepsis in Preterm Infants ”
Leena Bhattacharya, MD | INFECTIOUS DISEASES | Mentors: Karen Mestan, MD and Ram Yogev, MD
SECOND YEAR FELLOW BASIC RESEARCH AWARD:
“Targeting glycolysis and compensatory mitochondrial metabolism in neuroblastoma with FDA-approved ritonavir and metformin”
Surabhi Batra, MD | HEMATOLOGY, ONCOLOGY | Mentors: Malathy Shanmugam, PhD and Steven T. Rosen, MD
SECOND YEAR FELLOW CLINICAL RESEARCH AWARD:
“The effect of maternal race/ethnicity and weekend birth on induction of labor at 34 weeks' gestation ”
Gustave Falciglia, MD | NEONATOLOGY | Mentor: Karna Murthy, MD, MSc
THIRD YEAR FELLOW BASIC RESEARCH AWARD:
“Novel GCSFR mutation found in patients with SCN, CNL, and AML: a new oncogene”
Taly Glaubach, MD | HEMATOLOGY/ONCOLOGY | Mentor: Seth J Corey, MD/MPH
THIRD YEAR FELLOW CLINICAL RESEARCH AWARD:
“Resident Education in the Era of Work Hour Restriction: a Prospective Observational Study of PICU Bedside Rounds ”
Tara Petersen, MD | CRITICAL CARE | Mentor: Melissa L. Brannen, MD, MEd
POSTDOC RESEARCH AWARD:
“Reduction in microglial activation following experimental traumatic brain injury is associated with greater anxiety
and depression”
Chunshu Piao, PhD | NEUROLOGY & NEUROBIOLOGY PROGRAM
Mentors: Hantamalala Ralay Ranaivo, PhD and Mark S. Wainwright MD, PhD
JUDGES’ AWARD:
“Periostin is Upregulated in the Coronary Arteries of Patients with Kawasaki Disease ”
Rebekah Reindel, MD | INFECTIOUS DISEASES | Mentor: Anne Rowley, MD
JUDGES’ AWARD:
“TRPV1 Mediates Chronic Pain After Murine Urinary Tract Infection ”
John Rosen, MD |GASTROENTEROLOGY, HEPATOLOGY & NUTRITION | Mentor: David Klumpp, PhD
RESEARCH SCHOLARS DAY
2013 WINNERS
R E S E A R C H R E S E A R C H Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 8
R E S E A R C H R E S E A R C H New Awards Received in May 2013
Robert Garofalo, MD
YMAP: Young Men’s Affiliation Project of HIV risk & prevention venue
The University of Texas Houston Health Science Center/NIH subcontract
CVCTPlus: A couples-based approach to linkage to care and ARV adherence
Emory University/NIH subcontract
Stewart Goldman, MD
A phase III, multi-center, open label, randomized, controlled study of the efficacy and
safety of oral LDE225 versus Temozolomide in patients with Hh-pathway activated
relapsed medulloblastoma
Novartis Pharmaceuticals Corporation
Jane Holl, MD
National Children’s Study: Vanguard study (South ROC)
Northwestern University/NIH Subcontract
Marisa Klein-Gitelman, MD
An observational registry of Abatracept in patients with Juvenile Idiopathic Arthritis
Bristol-Myers Squibb Company
Rajesh Kumar, MD
Multi-level understanding of social contributors to SES disparities in Asthma
Northwestern University/NIH subcontract
Susanna McColley, MD
A phase 3 randomized, double blind, placebo-controlled, parallel group study to
evaluate the efficacy and safety of Lumacaftor in combination with Ivacaftor in sub-
jects aged 12 years and older with Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
An ocular safety study of Kalydeco-treated pediatric patients 11 years of age or
younger with Cystic Fibrosis
Vertex Pharmaceuticals Incorporated
Douglas Nordli, MD
Prevention of West syndrome
Citizens United for Research in Epilepsy, Inc.
Jacqueline Pongracic, MD
The PRROTECT (Peanut Reactivity Reduced by Oral Tolerance in an anti-IgE Clinical
Trial) study
Children’s Hospital of Boston/Subcontract
Alexis Thompson, MD
A phase 3 study for the efficacy and safety comparison of Prasugrel and placebo in
pediatric patients with Sickle Cell Disease H7T-MC-TADO
Eli Lilly and Company
Jacek Topczewski, PhD
Identification of a gene involved in late stages of zebrafish craniofacial development
(NRSA pre-doctoral fellowship for Rebecca Anderson)
National Institute of Dental and Craniofacial Research
Sharon Unti, MD
Multi-center trial of limiting PGY 2 and 3 resident work hours in ICU patient safety
Brigham & Women’s Hospital/NIH subcontracts
Donald Zimmerman, MD
Travel grant application for PES 2013
Pediatric Endocrine Society
New Awards Received in June2013
Adam Becker, PhD
CPS Summer Bridge Curriculum
Chicago Public Schools
Anne Berg, PhD
Pediatric Epilepsy Research Consortium (PERC): Early Onset Epilepsy Consortium
(EOEC) infrastructure grant
Pediatric Epilepsy Research Foundation
Ellen Brooks, PhD
Prognostic biomarkers to predict progression of pediatric chronic kidney disease
National Institute of Child Health and Human Development
Barbara Burton, MD
A multicenter, open-label BMN 110 US Expanded Access Program (BMN 110 US EAP)
to provide BMN 110 to patients diagnosed with MPS IVA
BioMarin Pharmaceutical Inc.
Raye-Ann DeRegnier, MD
NICHD Maternal Fetal Medicine Units Network: A randomized trial of Thyroxine thera-
py for subclinical hypothyroidism or hypothyroxinemia diagnosed during pregnancy
Northwestern University/NIH subcontract
Christine DiDonato, PhD
Spina Muscular Atrophy: inducing SMN expression
National Institute of Neurological Disorders and Stroke
Stewart Goldman, MD
Children’s Oncology Group Phase 1/Pilot Consortium
Children’s Hospital of Philadelphia/NIH subcontract
Rajesh Kumar, MD
Choriamnionitis and Methylation in Asthma Disparities (CMAD) study
American Academy of Allergy, Asthma & Immunology
John Millichap, MD
Rational Intervention for KCNQ2 Epileptic Encephalopathy (RIKEE) Network
Baylor College of Medicine/Subcontract
Douglas Nordli, MD
Consequences of prolonged febrile seizures in childhood
Albert Einstein College of Medicine/NIH subcontract
M. Bento Soares, PhD
Radial glia-specific nanoplatforms for in vivo non-invasive diagnostic imaging of neural
stem cells
Northwestern University
Simone Sredni, MD, PhD
Avoiding unnecessary toxicity and improving survival of children with low grade gliomas
Voices Against Brain Cancer
Jacek Topczewski, PhD
Pilot experiment for AbbVie
AbbVie, Inc.
Ram Yogev, MD
A phase 1, open label, single dose study to investigate the pharmacokinetics, safety and
tolerability of Dalbavancin in hospitalized children aged 3 months to 11 years receiving
standard intravenous anti-infective treatment for Bacter
Duke University/Subcontract
FROM THE OFFICE OF SPONSORED PROGRAMS — New Awards
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 9
Emalee Flaherty , MD Marisa Klein-Gitelman, MD, MPH Cynthia Mears, DO Mary Clyde Pierce, MD Professor Professor Professor Professor Academic General Pediatrics Rheumatology Community-Based Primary Care Emergency Medicine
Christine diDonato, PhD Craig Garfield, MD Jolanta Topczewska, PhD Karen Mestan, MD Associate Professor (with tenure) Associate Professor Associate Professor (Research) Associate Professor Human Molecular Genetics Hospital-Based Medicine Developmental Biology Neonatology
Mary Nevin, MD Alan Rosenblatt , MD Julie Stamos, MD Associate Professor Associate Professor (Clinical) Associate Professor
Pulmonary Medicine Community-Based Primary Care Infectious Diseases
FACULTY PROMOTIONS ANNOUNCEMENT
We are delighted to announce the faculty promotions that have been approved by Northwestern University, effective
September 1, 2013. For these individuals, consideration of their promotions started over a year ago. Each was evaluated
by the Department Appointment, Promotions, and Tenure (APT) Committee, one or more medical school committees,
multiple outside referees, Dean Neilson, and, ultimately, Provost Linzer. The elaborate steps and great care involved in
this process are a reflection of the importance that the university ascribes to a positive decision for promotion. These
faculty have made outstanding contributions to the mission of the university and have distinguished themselves and their
institutions in their work.
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 10
Rachel Robison, MD Suzanne M Schmidt, MD Assistant Professor Assistant Professor Allergy/Immunology Emergency Medicine
Robert Greenberg Melanie Makhija Deepa Nair Srishti Nangia Assistant Professor Assistant Professor Assistant Professor Assistant Professor Hospital-Based Medicine Allergy/Immunology Emergency Medicine Neurology
Ashish Chogle, MBBS Leslie Cordes Christopher Donohoe Naomi Fogel
Assistant Professor Assistant Professor (Clinical) Assistant Professor (Clinical) Assistant Professor Gastroenterology/Hepatology/Nutrition Community-Based Primary Care Community-Based Primary Care Endocrinology
Not pictured:
Marta Perez
Assistant Professor (Neonatology)
Parag Shah
Assistant Professor (Hospital-Based Medicine)
Angkana Roy
Assistant Professor (Clinical)
FACULTY PROMOTIONS ANNOUNCEMENT
July 15, 2013 Two Pediatrics Faculty Members Receive Searle Teaching Fellowships
July 3, 2013 Ruchi Gupta, MD, MPH Discusses New Study Linking Antibiotics to Eczema
June 28, 2013 Cynthia LaBella, MD Notes Changes in Cheerleading May Lead to More Injuries
June 26, 2013 Fellow Reeti Chawla, MD Presents on Genetics and Newborn Adiposity at National Meeting
June 12, 2013 Sookyong Koh, MD, PhD Contributes to New Therapy for Febrile Seizures in Children
May 20, 2013 Leon Epstein, MD Investigates Link Between Circadian Rhythms, Colic, and Migraines
NE W S H IG H L IG H TS : Faculty Research, Ref lect ions , & More in the Media
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 11
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 12
NEW FACULTY MEMBERS
We often welcome a bumper crop of new faculty members in the summer, and this year is no exception.
Between the beginning of July and the middle of August 2013, sixteen new physicians will be joining our
department faculty. Several recent graduates of our pediatric residency program have stayed on as
hospitalists, designated with an asterisk below. Others come to us from equally esteemed positions from
across the country. The Department of Pediatrics Faculty Affairs Board (FAB) will be sponsoring a
meet-and-greet event onsite at Lurie Children’s later this summer. Details for this event will be
forthcoming. Meanwhile, please extend your greetings to these new colleagues.
07/01/2013 Zarina Dohadwala, MD * Hospital-Based Medicine Lurie/Prentice
07/01/2013 James Felker, MD * Hospital-Based Medicine Lurie/Prentice
07/01/2013 Christine Higham, MD * Hospital-Based Medicine Lurie/Prentice
07/01/2013 Kiley Johnson, MD * Hospital-Based Medicine Lurie/Prentice
07/01/2013 Irini Kolaitis, MD * Hospital-Based Medicine Lurie/Prentice
07/01/2013 Alina Lopez, MD * Hospital-Based Medicine Lurie/Prentice
07/01/2013 Melisa Nassin, MD Hospital-Based Medicine Lurie/Prentice Recently completed residency at Boston Children’s Hospital and Boston Medical Center 07/01/2013 Kirsten Rose-Felker, MD * Hospital-Based Medicine Lurie
07/01/2013 Courtney Weems, MD Hospital-Based Medicine Lurie/LaRabida Recently completed residency at University of Chicago 07/01/2013 Jacqueline Winikoff Wallis, MD * Hospital-Based Medicine Lurie/Prentice
07/12/2013 Kavita Hodgkins, MD Kidney Diseases Lurie/Prentice
07/15/2013 Mahima Keswani, MD Kidney Diseases Lurie/Prentice Most recently Attending and Assistant Professor (Clinical) joining from Children’s National Medical Center 08/01/2013 Mjaye Mazwi, MD Cardiology Recently completed fellowships in Cardiology and Critical Care/Anesthesia at Boston Children’s Hospital
08/01/2013 Lauren Marsilio MD Critical Care Medicine Recently completed fellowship in Critical Care at Children’s Hospital of Philadelphia 08/01/2013 Zachary Pittsenbarger, MD Emergency Medicine Recently completed fellowship and chief fellow year in Emergency Medicine at Boston Children’s Hospital
08/01/2013 Patrick Myers, MD Neonatology Completed fellowship in Neonatology and served as Clinical Neonatology Associate at University of Chicago
(from L to R)
Zarina Dohadwala, MD
James Felker, MD
Christine Higham, MD
Kavita Hodgkins, MD
Kiley Johnson, MD
Irini Kolaitis, MD
Alina Lopez, MD
Zachary Pittsenbarger, MD
Kirsten Rose-Felker, MD
Courtney Weems, MD
Jacqueline Winikoff-Wallis, MD
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 13
McGaw Medical Center of Northwestern University
Department of Pediatrics | New Fellows, July 2013
Yuemi An-Grogan, MD
Emergency Medicine
Seema Bansal, MD
Clinical Neurophysiology
Jillian Bybee, MD
Critical Care Medicine
Joseph Casadonte, MD
Cardiology
Christina Cochran, MD
Emergency Medicine
James Feinstein, MD, MPH
Academic General Pediatrics
Rebecca Garcia-Sosa, MD
Child Neurology
Tracy Gertler, MD
Child Neurology
Katherine Gregersen, DO
Critical Care Medicine
Barry Pelz, MD
Allergy/Immunology
Tyler Harris, MD
Cardiology
Karla Wehrheim, MD
Cardiology
Luda Sorin, MD
Clinical Neurophysiology
Vishal Gunnala, MD
Critical Care Medicine
Astha Sharma, MD
Critical Care Medicine
Adnan Mir, MD, PhD
Dermatology
Rachel Kadakia, MD
Endocrinology
Chantal Lucia-Casadonte, MD
Gastroenterology/Hepatology
Michael Malandra, MD
Gastroenterology/Hepatology
Prev. Position: Asst. Professor,
University of Colorado Denver
Prev. Position: Pediatrics Resident,
NUFSM/Lurie Children’s
Prev. Position: Pediatrics Resident,
University of Chicago
Prev. Position: Pediatrics Resident,
NUFSM/Lurie Children’s
Prev. Position: Pediatrics Resident,
NUFSM/Lurie Children’s
Prev. Position: Pediatrics Resident,
NUFSM/Lurie Children’s
Prev. Position: Pediatrics Resident,
Miami Children’s Hospital
Prev. Position: Child Neuro Resident,
Children's National Medical Center
Prev. Position: Child Neuro Resident,
Loma Linda University
Prev. Position: Pediatrics Resident,
Phoenix Children’s Hospital
Prev. Position: Pediatrics Resident,
University of Connecticut
Prev. Position: Med/Peds Resident,
Loyola University
Prev. Position: Pediatrics Resident,
SUNY Upstate—Syracuse
Prev. Position: Dermatology Resident,
NYU School of Medicine
Prev. Position: Research Fellow,
Northwestern Memorial Hospital
Prev. Position: Pediatrics Resident,
Medical University of South Carolina
Prev. Position: Pediatrics Resident,
NUFSM/Lurie Children’s
Prev. Position: Pediatrics Resident,
Miami Children’s Hospital
Prev. Position: Pediatrics Resident,
University of Tennessee
Lacey Kruse, MD
Dermatology
Prev. Position: Dermatology Resident,
Southern Illinois University
Northwestern University Feinberg School of Medicine | Department of Pediatrics | Newsletter, Jul. 2013 | P. 14
McGaw Medical Center of Northwestern University
Department of Pediatrics | New Fellows, July 2013
Matthew Abts, MD
Pulmonary Medicine
Sherif Badawy, MD
Hematology/Oncology
Rakhee Bowker, MD
Neonatology
Larisa Broglie, MD
Hematology/Oncology
Eileen Broomall, MD
Neurocritical Care
Amy Feldman, MD
Hepatology/Transplant
Marielle Fricchione, MD
Infectious Diseases
Paul Lee, MD, PhD
Hematology/Oncology
Mina Kim, MD
Kidney Diseases
Shayna Hibbs, MD
Neonatology
Grace Lin MD
Neonatology
Vamshi Rao, MD
Neuromuscular Medicine
Natasha Pillay Smiley, MD
Neurooncology
Sarah Kinsella, MD
Sports Medicine
Pallavi Patwari, MD
Sleep Medicine
The Department of Pediatrics fellowship programs have grown significantly in
recent years, from 60 positions in 2003-2004 to 85 positions in 2013-2014.
Many of these additional fellows are in newer subspecialties, like Sleep Medicine
and Child Abuse Pediatrics, or in advanced programs, such as Neurocritical
Care and Neuromuscular Medicine.
If you are a graduate of one of our fellowships, we encourage you to keep in
touch with us. Please send updated information on your current position and
contact details to [email protected].
Prev. Position: Pediatrics Resident
Mount Sinai Medical Center
Prev. Position: Pediatrics Resident,
NUFSM/Lurie Children’s
Prev. Position: Peds GI Fellow,
Children’s Hospital of Colorado
Prev. Position: Pediatrics Resident,
Rush University Medical Center
Prev. Position: Pediatrics Resident,
University of Chicago
Prev. Position: Pediatrics Resident
University of Iowa
Prev. Position: Pediatrics Resident,
Columbia University
Prev. Position: Pediatrics Resident,
New York University
Prev. Position: Pediatrics Resident,
NUFSM/Lurie Children’s
Prev. Position: Child Neurology
Mayo Clinic
Prev. Position: Child Neuro Resident,
NUFSM/Lurie Children’s
Prev. Position: Pediatrics Resident,
NUFSM/Lurie Children’s
Prev. Position: Heme/Onc Fellow,
Nationwide Children’s Hospital
Prev. Position: Pediatrics Resident,
NUFSM/Lurie Children’s
Prev. Position: Attending, Center for
Autonomic Medicine, NUFSM