crouzon's syndrome: case report
TRANSCRIPT
ORAL AND MAXILLOFACIAL PATHOLOGY OOOO
e190 Abstracts February 2014
PE-301 - SIALOLIPOMA: A RARE TUMOR RECENTLYRECOGNIZEDASASEPARATEENTITY. TAIANE PRISCILAGARDIZANI, JOSÉ BURGOS PONCE, HELITON GUSTAVODE LIMA, KAREN HENRIETTE PINKE, HENRIQUEMARTINS FRANÇA BORGES, CLEVERSON TEIXEIRASOARES, VANESSA SOARES LARA. FACULDADE DEODONTOLOGIA DE BAURU (FOB) - UNIVERSIDADE DESÃO PAULO (USP).
Sialolipoma is a new category of benign lipomatous tu-mors of the salivary glands, that is also a rare variant ofsalivary gland lipoma. Characteristics include mature adiposeelements and salivary gland tissue that is well-circumscribedby a thin fibrous tissue. Until now, fewer than 40 cases havebeen reported. Few occurred in the minor salivary glands andone was in the tongue. Woman, 37, had an asymptomatic andslow-growing exophytic nodular lesion on the tongue thatmeasured 1 cm and had well-defined boundaries. The histo-pathological diagnosis was sialolipoma. The description ofsialolipoma is useful for distinguishing it from other lesionsthat also affect adipose and gland tissues; these include lip-omatosis, fibrolipoma, lipoma, and lipomatous adenomas. Weregard sialolipoma as a distinct variant of lipoma that canoccur in both the major and minor salivary glands. The his-togenesis of these lesions is unclear, and surgical resection isan appropriate treatment.
PE-302 - SIALOLITHIASIS IN BUCCAL MUCOSA OFELDERLY PATIENT: CASE REPORT. ALISSON CARDOSOALVES, MILENA RAYANE DE ANDRADE TEIXEIRA, JOSÉCADMO WANDERLEY FILHO, SÉRGIO HENRIQUEGONÇALVES DE CARVALHO, CASSIANO FRANSCISCOWEEGE NONAKA, GUSTAVO PINA GODOY, POLLIANNAMUNIZ ALVES. UEPB.
Sialoliths are calcareous concretions causing obstruction ofa salivary gland or its excretory duct, mainly in the subman-dibular gland. Only 2% occur in minor salivary glands. Man, 80,complained of a small asymptomatic nodular lesion on the leftbuccal mucosa. Palpation revealed the presence of small endo-phytic nodule. The preliminary diagnosis was traumatic neu-roma. Excisional biopsy was performed; the macroscopicexamination showed a rounded lesion of firm consistency withcalcified material inside. Microscopically there was a fragmentcalcified in concentric laminations contained within an enlargedsalivary duct. Adjacent to this there was a salivary parenchymawith chronic sialadenitis. The definitive diagnosis was sialoli-thiasis. The patient has been followed up for 6 months with norecurrence. Dentists should have accurate knowledge of sialo-liths to make an accurate diagnosis and provide appropriatetherapy.
PE-303 - SIALOLITHIASIS IN THE SUBMANDIBULARGLAND PRESENTING AS AN INFLAMMATORYFIBROUSHYPERPLASIA AND SECONDARY INFECTIONIN THE FLOOR OF THE MOUTH: CASEREPORT. MARCOS ANTONIO NUNES COSTA SILAMI,DANIELLE RESENDE CAMISASCA, MARCIA DUARTESOTHER, REBECA DE SOUZA AZEVEDO, SILVIAPAULA DE OLIVEIRA. ODONTOCLÍNICA CENTRAL DOEXÉRCITO (OCEX).
Sialolithiasis is the development of mineralized structureswithin excretory salivary ducts or glandular parenchyma. A largesialolith of the left submandibular gland is reported. Man, 55,presented an exophytic, irregular, firm, normochromic, andpainful nodule in the left posterior region of the floor of themouth. The lesion excreted pus and was present for 3 months.He gave a history of calcification in the submandibular glandover 10 years. Panoramic radiographs revealed coalescing radi-opacities; submandibular gland ultrasonography showed a 0.2-cmcalcification. Soft tissue biopsy results were compatible withinflammatory fibrous hyperplasia. The patient was given antibi-otics and anti-inflammatory agents. At follow-up the lesion wassmaller, and a hard yellowish nodule was observed. Surgicalexploration removed this calcification. A second panoramicradiograph revealed a small calcification, but the pain and pusexcretion had ceased. The definitive diagnosis was sialolithiasis.This case shows sialolithiasis with an unusual clinical presenta-tion and satisfactory outcome.
PE-304 - SIMPLE BONE CYST OF BILATERAL OCCUR-RENCE: CASE REPORT. JAMILE DE OLIVEIRA SÁ,ADRIANO FREITAS DE ASSIS, JANDSON MICHEL DOSSANTOS, CAMILA SANE VIENA, PATRÍCIA DE CASTROVEIGA, ALENA RIBEIRO ALVES PEIXOTO MEDRADO,SÍLVIA REGINA DE ALMEIDA REIS. FACULDADE BAHI-ANA DE MEDICINA E SAÚDE PÚBLICA.
Simple bone cyst is an intraosseus, non-neoplastic lesionthat affects especially the jaw. Higher incidences are reported forthe body and symphysis. The etiology remains controversial.This report presents a clinical case of bilateral lesions discoveredon routine radiographic examination. Mulatto man, 19, hadundergone clinical examinations and imaging for bilateral le-sions, then was referred for evaluation by an Oral and Maxil-lofacial Surgery service. Surgical aspiration from both lesionsshowed clear liquid and the remaining cavity consisted of softtissue. Pathological examination of both lesions revealed anarrow band of loose connective tissue with no epithelial lining.The diagnosis was simple bone cyst of multiple occurrence. Theabsence of root resorption, the lamina dura, and the presence ofinvolved teeth whose pulp remained vital are referenced in theliterature. It is rare to see these cysts in more than oneanatomical site.
PE-305 - CROUZON’S SYNDROME: CASE REPORT.CAROLINE FARIAS LEMOS, BERNANDO FERREIRABRASILEIRO, LUIZ CARLOS FERREIRA DA SILVA,NAYANE CHAGAS CARVALHO, MARTA RABELLO PIVA.UNIVERSIDADE FEDERAL DE SERGIPE.
Crouzon’s syndrome (CS) is a rare condition that affectsthe development of the craniofacial skeleton. Although un-common, CS has a 50% risk of transmission when one parenthas the disease. Man, 19, was diagnosed with CS at age 12 butrefused surgical treatment. He returned complaining of toothpain and difficulty opening the mouth. Physical examinationshowed exophthalmos, flattening of the occipital protuberanceof the frontal and occipital areas, prognathism, and deviatedseptum. Clinical examination revealed intraoral malocclusion,narrowing of the hard palate, limited mouth opening, andseveral carious lesions. Treatment requires a multidisciplinary
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Volume 117, Number 2 Abstracts e191
approach involving physiotherapy, TMA surgery, and clinicaldental care.
PE-306 - SJOGREN’S SYNDROME: MANAGEMENT OFA CASE. SORAYA DE MATTOS CAMARGO GROSSMANN,PATRÍCIA CALDEIRA, MARIA AUXILIADORA VIEIRA DOCARMO, LUCINEI ROBERTODEOLIVEIRA, TUFI MEYER,RINALDO BORGES DE ALMEIDA. UNIVERSIDADE FED-ERAL DE MINAS GERAIS/UNIVERSIDADE VALE DO RIOVERDE.
Woman, 53, complained of “dry mouth and swallowingdifficulty.” In addition to the xerostomia, she had xerophthalmiaand was being treated for rheumatoid arthritis. Extraoral examshowed bilateral red eyes. Intraoral examination revealed drydull-looking mucosa. The result of a questionnaire about xero-stomia indicated she had moderate xerostomia. Stimulated andnonstimulated flow measurements indicated hyposalivation, andlaboratory tests were requested, showing she was ANA and RFpositive. Clinical findings indicated a diagnosis of Sjögren’ssyndrome, so an incisional biopsy was performed in the salivarygland in the lower lip. It showed focal areas of lymphocyticinfiltrate and destruction of ductal and acinar salivary glands,confirming the diagnosis of Sjögren’s syndrome. The patient wastreated with artificial saliva and alteration of certain habits. Shewas referred to an ophthalmologist and a rheumatologist and hasshown significant improvement in symptoms. (Support: CNPq;Fapemig).
PE-307 - SOFT TISSUE RECURRENCE AFTER TREATMENTOF AMELOBLASTOMA: CASE REPORT WITH CLINICO-PATHOLOGICAL CONSIDERATIONS. LEORIK PEREIRADASILVA,VANESSADECARVALHOMELO,CAMILACARLAMARIA XIMENES OLIVEIRA, EDMILSON ZACARIAS DASILVA JÚNIOR, EMANUEL DIAS DE OLIVEIRA E SILVA,EMANUEL SÁVIO DE SOUZA ANDRADE, ANA CLAUDIAAMORIM GOMES. FACULDADE DE ODONTOLOGIA DEPERNAMBUCO - UNIVERSIDADE DE PERNAMBUCO.
Ameloblastomas are locally aggressive jaw tumors with ahigh propensity for recurrence. They are believed to arise fromremnants of dental lamina or odontogenic epithelium. Radicalsurgery remains the therapy of choice. Patient, 69, was seenexactly 9 years after hemimandibulectomy for the treatment ofmulticystic ameloblastoma. The patient underwent a maxillofacialsurgery procedure at University Hospital Oswaldo Cruz in Per-nambuco, Brazil. She reported having two well-demarcated areasof painful swelling that measured about 4 cm in the submucosanext to a titanium bone plate used for reconstruction. Computedtomography and an incisional biopsy were performed. The tumorswere diagnosed as ameloblastoma. They were resected, and theanatomopathological analyses showed predominantly follicularand acanthomatous ameloblastoma within intense cicatricialfibrosis, constituting a soft tissue recurrence. This report showsthe need to monitor ameloblastomas for a long-term period afterradical treatment.
PE-308 - SOLITARY PERIPHERAL OSTEOMA OF THEMANDIBLE: RARE CASE REPORT. DENISE HÉLENIMACULADA PEREIRA DE OLIVEIRA, ANA MIRYAMCOSTA DE MEDEIROS, ANTÔNIO DE LISBOA LOPESCOSTA, ÉRICKA JANINE DANTAS DA SILVEIRA. UNI-VERSIDADE FEDERAL DO RIO GRANDE DO NORTE.
Osteomas are relatively rare benign osteogenic neoplasmscharacterized by the proliferation of compact and/or cancellousbone. Osteomas can develop as peripheral (periosteal) massesattached to the cortical plates or as central lesions arising fromendosteal bone surfaces. Multiple osteomas of the facial bones arean important early marker for Gardner’s syndrome, but the soli-tary peripheral osteoma of the mandible is uncommon. Woman,39, was referred to the oral diagnostic service with a complaint ofpainful swelling in the mandible of about 2 years’ duration.Physical examination showed a hard, sessile mass measuring2 cm in diameter on the buccal side of the mandible in the regionof teeth #44 and #45. Microscopic examination of the surgicalspecimen showed chiefly mature lamellar bone containing a smallamount of bone marrow. A diagnosis of compact osteoma wasmade. Postoperative was uneventful and there has been norecurrence.
PE-309 - SOLITARY PLASMACYTOMA OF THEMANDIBLE: CASE REPORT. MARISOL MARTÍNEZMARTÍNEZ, ALICIA RUMAYOR PIÑA, KATYA PULIDODÍAZ, WILSON DELGADO AZAÑERO, OSLEI PAES DEALMEIDA. DEPARTMENT OF ORAL DIAGNOSIS, PIRA-CICABA DENTAL SCHOOL, STATE UNIVERSITY OFCAMPINAS.
Solitary plasmacytoma is a rare malignant tumor in thefamily of plasma cell proliferative diseases that affect bones. Amandibular location is extremely rare. Man, 48, presented a sol-itary plasmacytoma in his mandible. Panoramic radiographsrevealed a large irregular radiolucent lesion in the body of themandible. Histologically the lesion consisted of sheets of poorlydifferentiated plasma cells. The immunoprofile showed positivereactions to VS38c, CD138, and MUM-1. Low-index cell pro-liferation was analyzed with Ki-67. Monoclonality of the light(kappa) chains confirmed the diagnosis. Complementary testsruled out multiple myeloma. Appropriate treatment combinessurgery and radiotherapy. Careful surveillance is required becausethis lesion often progresses to multiple myeloma according to theliterature.
PE-310 - SPORADIC BURKITT’S LYMPHOMA: CASEREPORT IN A CHILD. MARCO ANTONIO ALVES DASILVA, ELISSAMA DE JESUS SENA REIS, JARIELLEMASCARENHAS OLIVEIRA ANDRADE, BRUNO CUNHAPIRES, VALÉRIA SOUZA FREITAS, TARSILA DECARVALHO FREITAS RAMOS, MÁRCIO CAMPOSOLIVEIRA. UNIVERSIDADE ESTADUAL DE FEIRA DESANTANA.
Burkitt’s lymphoma is an aggressive malignancy that canaffect children. This condition is characterized as an undifferen-tiated lymphoma caused by B lymphocytes. Dark-skinned boy, 6,was referred to a stomatology clinic for investigation of a cervicaltumor. After rigorous clinical evaluation, there were neither signsnor symptoms that justified odontogenic etiology. The broadimmunohistochemical panel of the incisional biopsy suggestedBurkitt’s lymphoma, so chemotherapy treatment was begun atan oncology therapy center. However, after the second cycle ofthe therapy, the patient developed serious complications and died.Although delays in diagnosing Burkitt’s lymphoma may allowthe disease to continue unchecked and hinder successful thera-peutic outcomes, early diagnosis of the disease plus appropriatetherapy can ensure significant cure rates.