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Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

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Page 1: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Correction of Ring Artifacts in Micro CT

Wes ArmstrongMedical Biophysics 3970Z

University of Western OntarioMarch 23, 2011

Page 2: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Introduction

Computed Axial Tomography• Compiles a series of 2D X –

rays into a 3D volume of data.

• Our Protocol: 1200 X – rays.

GE eXplore speCZT

Page 3: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Introduction

Ring Artifacts• Why do they happen?• Why are they a

problem?

Page 4: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Objective

To determine if ring artifacts in micro CT images up to a year old can be corrected using this bright field calibration

Page 5: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Approach

Correct images using a bright field acquired over 100 minutes.

Page 6: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Hypothesis

Null – There will be no difference in the standard deviation (SD) of the grey scale values in the images before and after the bright field correction.

Alternate – There will be a difference in the standard deviation (SD) of the grey scale values in the images before and after the bright field correction.

Page 7: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Methods

• Reconstruct the images using the 100 minute bright field.

• Once corrected compare the standard deviations in various regions of interest (ROI) using Microview.

• Measure standard deviation due to photon counting noise

• Use quadature equation to determine the standard deviation due to the rings.

Page 8: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Results

April July November December January January0

20

40

60

80

100

120

140

160

180

ROI 1 (Center of the Ring Artifacts)St

anda

rd D

evia

tion

Paired t – test: p = 3.89298 x 10-7

Page 9: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

ResultsRegion of Interest Average

% ReductionAverage Reduction

in SDP Value*

Center of Rings 39.57 79.04 3.89298 x 10-7

Above Center of Rings

47.03 28.05 0.007266483

In Object 65.28 13.58 0.00673873

Outside Object 50.78 15.51 0.000117016

*Calculated using a paired, two – tailed t-test

Page 10: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Results

Before Correction After Correction

Page 11: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Discussion

• Accept the alternate hypothesis for ring artifact correction.

- Amount of correction decreases as distance from the center of the rings increases.

- GE Healthcare - Fine tuning

Page 12: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Conclusions

• Using the 100 minute bright field in reconstructions significantly reduces the ring artifacts.

Page 13: Correction of Ring Artifacts in Micro CT Wes Armstrong Medical Biophysics 3970Z University of Western Ontario March 23, 2011

Acknowledgements

Dr. David Holdsworth, PhD- Professor, Departments of Medical Biophysics and Surgery,

Shulich School of Medicine and Dentistry, UWO.- Scientist, Robarts Research Institute.- Dr. Sandy Kirkley Chair in Musculoskeletal Research.

Matt Teeter, BSc - PhD candidate