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Tamm emagi Lun g Cancer Risk Predict ion Calculator

Calculator predicting 6-year risk of lung cancer by the Tammemagi (PLCOM2012)

Instructions: For the characteristics described in Column A fill in the individual's

Note: Values in columns C to F can be ignored and should not be changed.

Characteristics to be entered

Enter

Values

Centered or

referent group

Age in years 55 62

Education (enter the highest level obtained)

1 = less than high school grad;

2 = high school grad;

3 = Post high school training;

4 = Some college;

5 = College grad;

6 = Postgraduate/professional.

4 4

Body Mass Index (BMI, weight in kg/height in meters^2) 28 27

COPD, emphysema or chronic bronchitis (0=No; 1=Yes) 0 0

Personal history of cancer (0=No; 1=Yes) 0 0

Family history of lung cancer (0=No; 1=Yes) 0 0

Race/ethnicity

White (referent group) (0=No; 1=Yes) 1

Black (non-Hispanic) (0=No; 1=Yes) 0

Hispanic (0=No; 1=Yes) 0

Asian (0=No; 1=Yes) 0

American Indian/Alaskan Native (0=No; 1=Yes) 0

Native Hawaiian/Pacific Islander (0=No; 1=Yes) 0

Smoking status,

0 = Former-smoker

1 = Current-smoker

0

Average number of cigarettes smoked per day** 20 0.097845839

Duration smoked (years) 30 27

Years ago quit smoking. Enter zero for current smokers. 15 10

Model constant

Probability of lung cancer = 0.005


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* Reference: Tammemagi et al. Selection Criteria for Lung-Cancer Screening. NEJM.

** Transformation of smoking intensity =(((H_smokdday/10)^-1)-0.4021541613)

Example: The 6-year risk of lung cancer in a white

individual who is 55 years old, has some college

education, a BMI of 28, who is a former smoker who quit15 years ago and smoked on average 20 cigarettes per

day for 30 years is estimated to be 0.005 or 0.5%.

NOTE: This calculator was developed and tested in Microsoft Excel for Mac 2011 v


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model.* Version 22FEB13MT

values in Column B.

Coefficient

Contribution to

estimate ORs

0.0778868 -0.5452076 1.08

-0.0812744 0 0.92

-0.0274194 -0.0274194 0.97

0.3553063 0 1.43

0.4589971 0 1.58

0.587185 0 1.80

0 0

0.3944778 0 1.48

-0.7434744 0 0.48

-0.466585 0 0.63

0 0

1.027152 0 2.79

0.2597431 0 1.30

-1.822606 -0.178334413 nonlinear

0.0317321 0.0951963 1.03

-0.0308572 -0.154286 0.97

-4.532506 -4.532506

xb = -5.342557113

EXP(xb) = 0.0048


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013;368(8):728-36.

rsion 14.0.0.


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Individual Disclaimer

information provided here should not be substituted for a medical examination or physicians

advice, diagnosis or treatment. Your doctor is the most appropriate person to provide you

with guidance on specific health issues. If you are currently ill or have symptoms, seek the

help of your health care provider. If you are a current smoker, one of the most important

health decisions you can make, is to quit smoking. Your doctor should be able to provide you

Commercial Disclaimer

Tammemagi Lung Cancer Risk Calculator, (c) 2013, Brock University (the "Software").

The Software remains the property of Brock University ("the University").

hope that it will be useful, but in order that the University as a charitable foundation protects

its assets for the benefit of its educational and research purposes, the University makes clear

that no condition is made or to be implied, nor is any warranty given or to be implied, as to the

accuracy of the Software, or that it will be suitable for any particular purpose or for use under

against any and all claims, damages and liabilities asserted by third parties (including claims

for negligence) which arise directly or indirectly from the use of the Software.or by any means, electronic or mechanical, without the express permission of the University,

with the following exception. The permission of the University is not required if the said

reproduction, modification, transmission or transference is done without financial return, the

conditions of this Licence are imposed upon the receiver of the product, and all original and

any financial return is received shall be defined as commercial use, and includes (1)

integration of all or part of the source code or the Software into a product for sale or license

by or on behalf of Licensee to third parties or (2) use of the Software or any derivative of it for

research with the final aim of developing software products for sale or license to a third party

or (3) use of the Software or any derivative of it for research with the final aim of developing

non-software products for sale or license to a third party, or (4) use of the Software to provide

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