complete blood count ppt

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Lab : CBC Hematology


Complete Blood Count

Complete Blood CountRBC : RBC Count, Hb, Hct, RBC indices (MCV, MCH, MCHC )WBC : WBC Count, WBC Differential.Platelet : Platelet Count, MPV. PDW



RBC Count

Normal Values

Adult Females : 4.0-5.5 mill/LAdult Male : 4.5-6.2 mill/LRBC indices (MCV, MCH, MCHC, RDW)

Mean corpuscular volume (MCV) is a measurement of the average size of a single red blood cell. Mean corpuscular hemoglobin (MCH) is a calculation of the average amount of hemoglobin inside a single red blood cell. Mean corpuscular hemoglobin concentration (MCHC) is a calculation of the average concentration of hemoglobin inside a single red blood cell.The Mean Cell Volume (MCV) Normal Values Adults 7696 fl.MCV is reduced in microcytic anemias MCV is raised in macrocytic anemias The Mean Cell Hemoglobin (MCH) Normal MCH in adults is from 27 to 32 pg. MCH is reduced in hypochromic anemias. The Mean Cell Hemoglobin Concentration (MCHC) 3135 g% This too, is low in hypochromic anemias.

InterpretasiLow MCV : Indicates RBCs are smaller than normal (microcytic); caused by iron deficiency anemia or thalassemias, for example.High MCV : Indicates RBCs are larger than normal (macrocytic), for example in anemia caused by vitamin B12 or folate deficiency, liver disease, hypothyroidismWBC CountIn the total leukocyte count, the reference interval for adults is 4.511.0 109/L.

Concise Book of Medical Laboratory Technology: Methods and InterpretationsWBC Differential

Pathway for differential cell count.

Normal Values ( Adult)Neutrophil (segs) : 54-62%Neutrophil (bands) : 3-5%Eosinophils : 1-4%Basophils : 0.75%Monocyte : 2-10%Lymphocyte :20-40%Concise Book of Medical Laboratory Technology: Methods and Interpretations

Type of Cell Increase DecreaseWhite Blood Cells (WBC): leukocytosis leukopenia lymphocytes lymphocytosis lymphocytopenia granulocytes: granulocytosis granulocytopenia or agranulocytosis neutrophils neutrophilia neutropenia eosinophils eosinophilia eosinopenia basophils basophilia basopeniaInterpretasiInterpretasiNeutrophil granulocytes: May indicate acute bacterial infection. May also be raised in acute viral infections. Lymphocytes: Higher with some viral infections such as glandular feverMonocytes: May be raised in cronic bacterial infection, tuberculosis, malaria, Eosinophil granulocytes: Increased in parasitic infections, asthma, or allergic reaction. Basophil granulocytes: May be increased in bone marrow related conditions such as leukemia or lymphomaPlatelet CountReference values for platelet counts are 150450 109/L.

Concise Book of Medical Laboratory Technology: Methods and InterpretationsInterpretasiThrombocytopenia: Viral infection (mononucleosis, measles, hepatitis), Platelet autoantibody, Drugs (acetaminophen, quinidine, sulfa drugs), Autoimmune disorders, Chemo or radiation therapyThrombocytosis: Cancer (lung, gastrointestinal, breast, ovarian, lymphoma), Iron deficiency anemia, Hemolytic anemia

Mean platelet volume (MPV) : It is a calculation of the average size of platelets.

Reference values for MPV are approximately 6.512 fL in adults.

Low Result : Indicates average size of platelets is small; a low MPV may mean that a condition is affecting the production of platelets by the bone marrow. High Result : Indicates a high number of larger,this may be due to the bone marrow producing and releasing platelets rapidly into circulation.Platelet distribution width (PDW) : It reflects how uniform platelets are in size.


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