Bone

Blood vessel

Collagen Fibres

Tendon

FasciculeMuscle

The most complete booklet on joints ever produced!presents

Preface 02

Introduction 03

Roles of collagen in the human body 04

Collagen, the glue of the body! 06

The virtues of amino acids 07

Some amino acids found in collagen 08

Importance of amino acids in cartilage 10

The role of collagen in the skeleton 12

Tendons act as elastic bands of the body 13

The role of collagen in ligaments 14

Muscle strength depends on muscular tissue 15

Collagen and aesthetics 16

Refreshing sleep 17

Tendinitis and sports 18

Genacol : success without boundaries 19

Genacol : Clinical studies 20

Genacol Original Formula 21

Genacol Instant 22

Genacol Plus 23

Genacol Fast Action 24

Genacol Triple Action 25

Frequently asked questions 26

Testimonials 30

contentsTable

of

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Dear Readers,

Science evolves at a rapid pace and scientists around the world are busy finding valuable solutions to many ailments that plague humankind. However, it is not always easy to shift through the numerous findings that reach us through various media whose quality and validity is sometimes hard to assess. This booklet is designed to provide you with accessible and reliable scientific explanations concerning joint pain and its causes. More specifically, it deals with the problems that arise from a lack of collagen.

Indeed, you will learn how vital this protein is for the body. In fact, as we humans age, our bodies produce less and less collagen. The decline begins in the thirties and becomes much more significant from the fifties onward. The lack or inadequate use of collagen by our bodies participates in the aging process and its associated symptoms. After reading this booklet, you should better understand why a collagen hydrolysate supplement, such as Genacol, offers the kind of help that you may need. Genacol represents a reliable solution that has been appreciated for over 10 years in Canada and in over forty countries around the world. The beneficial action of Genacol on joint health is scientifically proven by two independent clinical studies.

Happy reading!

Pierre S. Haddad, Ph.D. Professor in the Department of Pharmacology

Medicine Faculty Université de Montréal

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This multiple-benefit protein represents about a third of the proteins in the body. It supports, without exception, our tissues and organs, offering our body the necessary tonus to perform its vital functions.

Unfortunately, the aging process combined with modern life elements such as pollution, malnutrition, stress, lack of exercise, tobacco, alcohol, and medicine overdose affect this protein enormously. This situation creates a major impact on multiple aspects of our health, making our body vulnerable and prone to illness.

Scientific breakthroughs in relation to degeneration problems caused by aging, offer an interesting future perspective for those who want to improve their health and quality of life.

03

IntroductionWe are about to discover a protein that has in its structure an invaluable potential for health and well-being. Science acknowledges that collagen is the most important protein in the human body.

1804

We are about to discover a protein that has in its structure an invaluable potential for health and well-being. Science acknowledges that collagen is the most important protein in the human body.

Collagen is to the tissues in the human body, what steel rods are to reinforced concrete. If the steel rods of the frame are weak, all the structure weakens. More than twenty kinds of collagen are found in the tissues of the body. Depending on the different types of collagen contained in our body, we will find a variation in the sequences of amino acids. Let us examine collagen types I to V, which represent 99% of all the collagen found in our body. They are present in our body as follows:

Collagen is produced by specialized cells called fibroblasts and is gathered in the conjunctive tissues. The biological role of collagen has a double function. On the one hand, together with elastin and glycoproteins, it is responsible for the cohesion of tissues and organs. On the other hand, collagen gives these tissues and organs hydration, resistance, elasticity and flexibility properties.

With respect to conjunctive tissues, they form a weft rich in collagen, which is found practically in every part of our body. They mainly serve as support, filler, joint, insulation, protection or transport in the case of the blood system. Without this conjunctive tissue matrix rich in collagen that acts as “a sort of glue that keeps our body together,” we would be a puddle.

As previously mentioned, aging and lifestyle directly affect several metabolic processes such as our body’s ability to synthesize new proteins, including collagen. According to the Nutrition and Food Science Centre of the University of McGill, our body has to completely compensate with food the essential amino acids when it is unable to synthesize new proteins. It is also mentioned that if our body is under stress, due to injuries or degenerative problems related to aging, it would need even more amino acids than it normally does.

collagenRoles of

human bodyin th

e

Type I Bones, tendons, ligaments and skin

Type II Cartilages and structure of the eyes

Type III Liver, lungs and arteries

Type IV Kidneys and several internal organs

Type V Surface of cells, hair and placenta

The effects of aging, including a decrease in the synthesis of collagen proteins, appear when we are very young. If we analyze the available studies, this decrease starts at age 30 at an average of 1% per year. This phenomenon creates, in all our tissues and organs, a reduction of functions and a loss of resistance, elasticity and flexibility. This generates, in the short or medium term, a series of reactions that for most of us emerge as follows:

Even more ironically, in our early thirties, most of us accept to live with most of these discomforts as we do not experience any major health problems or we do not feel strong pain. However, as far as the reduction of collagen in our body is concerned, these problems are just the tip of the iceberg; as they announce, together with aging, direct effects on our health and quality of life.

So, what happens when this situation becomes a problem? To find out, let us analyze how amino acids, found in collagen, can offer an effective nutritional support to the main tissues in our body.

05

Roles of collagen in the human body (continued)

Bone

Blood vessel

Collagen fibres

Tendon

FasciculeMuscle

•Finewrinklesandwrinkles

•Lackoftonus

•Musclesoreness

•Jointandmuscularstiffness

•Slowerhealing ofwounds

•Morefrequentfatigue

06

Collagen is present in all multi-cellular organs in our body.

Collagen is the fibrous structural protein that makes up the white fibres (collagen fibres) of skin, tendons, bones, cartilage, and all other connective tissues. It is also found widespread in the gelatinous substances of the body to provide stiffening properties, such as in the vitreous humour of the eye. In other words, collagen is the natural protein that constitutes most of the body’s structural support and is the primary substance of connective tissue. It is this fibrous connective tissue that holds our body together.

Collagen gives to different organs and tissues their strength and elastic properties. Twenty-five percent of the protein weight in the human body and seventy-five percent of our skin are made of collagen. Collagen is part of the natural composition of our tendons, ligaments, joints, muscles, hair, skin, and vital organs. When there is a lack of collagen in the body, everything is affected. Weakness, fatigue, aches, pain, and an overall lack of energy are the main symptoms of a lack of collagen. In addition, all these symptoms increase with aging.

Besides its numerous structural properties, collagen serves as a main catalyst for growth and it repairs almost all the tissues of the body. Several diseases caused by aging are related to a lack of this vital protein that is collagen. When there is a lack of collagen, we get sick.

The production of collagen in the body slows down insidiously with age. It starts slowing down around thirty and decreases abruptly around fifty. A lack of collagen, or the inability to use it properly in our body, causes the early signs of aging.

of the body!glueCollagen,

the

Collagen fibres

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Proteins in our food contribute to the formation of all the tissues in the body.

Proteins in our food contribute to the formation of all the tissues in the body. When proteins are created in our body, sequences of amino acids relatively long called “polypeptides” are conceived in a determined order by our genetic code. The DNA (our genetic code) is our personal library where all the necessary information to the production and regeneration of our tissues and organs is contained. Therefore, our DNA plays a major role keeping one of the best-kept secrets in natural health. This secret is based on twenty amino acids that are the fundamental bricks from which all the living organisms are created.

“These twenty amino acids help form the 1600 proteins found in our body. For example, it is from these twenty amino acids extracted from food that our body can form the following elements: tendons, cartilage, bones, blood, hair, nails, skin, muscles and nerves. They can also help digestion (stomach enzymes), detoxify poisons, and fight illnesses.”

This means that, according to the regeneration needs our body has, the enzymes (which can be compared to construction workers) will gather amino acids to then duplicate the information in our DNA in order to build new proteins which will carry out specific functions in our body.

Below you will find, as an example, a concise summary of some amino acids found in collagen.

amino acids

The

virtuesof

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Arginine

Glycine

Leucine

Glutamine

0H

Gly GlyGly Gly GlyPro Pro Hypro Hypro HylysY X X X Y

0H

87 nm

0H

NH2

0,87 nm

08

• Indispensabletoeliminatetheammoniacreatedbyabaddigestion (ammonia is toxic for our cells)•Helpstheregulationofthemetabolismofproteins•Helpssecretethegrowthhormone(encouragesregeneration)•Supportstheimmunesystem(preventsillnessesandaging)•Hasfavourableeffectsonmalefertility

Arginine

•Hasascarringeffect(burns,postoperativetraumatisms)•Hasapositiveeffectoneyes,nervoussystemandmemory•Participatesinthesynthesisofproteinsoftheskin,collagenandDNA•Hasapositiveeffectagainstgout(jointpain)•Promotesdetoxification

Glycine

•Partofthemaincomponentsofcollagen•Promotesskin,joint,tendonandcartilagehealthHydroxylysine

•Partofthemaincomponentsofcollagen•PlaysamainroleinbonesandconjunctivetissuesHydroxyproline

•Essentialaminoacid•Participatesintheproductionofmuscularproteins• Importantelementinthedietoftheelderly• Importantforbrainandbalancefunctions

Leucine

The scientific community is currently studying its possible therapeutic effectsagainstaging,alcoholism,schizophrenia,Parkinson’sdisease,and epilepsy.•HasanimportantroleinthesynthesisofDNA•Helpsmemoryandbrainenergy

Glutamine

amino acids

collagen

Some

found in

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•Essentialaminoacid•PlaysanimportantroleinthefunctioningofproteinsIsoleucine

•Contributestobrainhealth(intellectualperformance)•EssentialtothesynthesisofvitaminB3(niacin)Alanine

•Greatamountinmuscletissues• Increasesimmunedefences•Hasapositiveeffectagainstcertain sexually transmitted diseases•Hasaneffectagainstagingand calcium bone loss•Detoxifiesheavymetalsfoundinsomefoods and in the environment•Itisoneofthemostimportantaminoacids for the elderly

Lysine

•Constituentofcollagen(collagenisthemain reservoir of proline, representing 50% of all the proline in the body)•Stimulatesscarring

Proline

•Itsconcentrationinourmusclesisconsiderable•Ensuresadaptationtostress•Controlsappetite•Beneficialagainstdepression

Tyrosine

•Sourceofmuscularenergy•Hasapositiveeffectagainststress•Helpssecretethegrowthhormone (encourages regeneration)•Offerssupportagainstliverdiseases

Valine

Some amino acids found in collagen (continued)

•Essentialaminoacid•Participatesinthestructureandfunctionsofproteins•Participatesincontrollingacidity

Histidine

10

It has been acknowledged that a hydrolyzed collagen supplement, as Genacol®, supplies amino acids that contribute to the formation of cartilage.

Cartilage is dense, elastic and very rich in collagen (almost 67%) of conjunctive tissue. It is found at the junction of several bone pieces of the skeleton. It looks like rubber and absorbs the impact caused by movement. It is cool-white and smooth and about 3 mm thick. There are many kinds of cartilage; the one found in the knees or the discs between the vertebrae is very rich in fibres and contributes to improving movement. In children, we find a growth cartilage that is later transformed into bone, allowing the bone to lengthen.

The cartilage is a living tissue. It is formed by chondrocyte cells (cartilaginous cells) that can be destroyed after a traumatism, an injury or a disease as arthritis. The most common form of arthritis is osteoarthritis, also known as “degenerative arthritis.” It is associated to a selective destruction of cartilage cells in joints and it commonly affects the hips, knees, shoulders and spine. The lack of cartilage causes slower healing, accelerates the friction between the bones, produces pain, and limits joint mobility.

The main reasons of the selective destruction of cartilage cells are caused by two phenomena. First, the production of collagen is reduced with the normal process of aging. Second, the blood’s immune system attacks the cartilage to develop antibodies.

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67%Collagen

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32%Other

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Consequently, the immune system’s response is to attack all the cartilage degenerating in the body. Therefore, even if there is a problem in one single place, for example a wrist, the other wrist, knees, back, hips and shoulders can also hurt.

During the last 25 years, the costs related to traditional treatments for arthritis rapidly increased worldwide from 65 billion dollars in 1994, to almost 500 billion nowadays.

In fact, arthritis represents more than twenty thousand deaths and two million hospitalizations every year, plus the cost of medication. With 60 million Americans suffering from arthritis, we are facing an epidemic. John Klippel, Medical Director of the Arthritis Foundation, states that it is time to act. Some clinical studies and testimonials have shown that some products, such as Genacol, offer one of the most effective natural solutions.

11Normal collagen fibres Arthritic collagen fibres

Importance of amino acids in cartilage (continued)

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Osteoarticular diseases represent half of all the chronic diseases in people over 60.

Their increasing incidence with an aging population constitutes a major issue. With regard to this reality, the United Nations has determined that the next decade will be dedicated to bones and joints.

Without a skeleton, our body would be a mass of soft flesh. The skeleton is made up of more than 200 bones, and carries out four main functions. First, the skeleton supports the body’s weight and works as an anchor point for all the muscles and soft organs. Second, the skeleton plays an important role as a protector. The skull protects the brain, the rib cage protects the heart and the lungs, and the vertebrae protect the spinal cord. Third, the skeleton has a storage function. It contains 99% of the mineral reserves in the body. Finally, it participates in the immune functions, as it helps form the white and red cells in the bone marrow.

During the process of aging, the decrease of collagen significantly affects our bone structure, since our body loses the collagen that is used to fix the minerals in the bones. This critical situation modifies the bones’ rigidity, flexibility and density, making them more fragile.

One of the most common diseases related to bone aging is osteoporosis. It is characterized by a loss of resistance of bones, which leads to fractures. According to the Tunisian Society of Internal Medicine, one of the markers of bone density is defined by the increase of the urinary levels of C telopeptides of type I collagen. Type I collagen is the one that acts as cement to help minerals fix in the bones. Thus, a lack of this type of collagen weakens bones due to a lack of calcium, phosphor and other minerals. When bones are more porous, they are more susceptible to fracture during a simple fall that would normally have no consequences. Osteoporosis appears progressively with age.

collagenskeleton

The role of

in the

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The dry weight of each wall of tendons is made up of more than 95% of collagen.

The ends of tendons, which are the most solid parts, are composed almost exclusively of collagen, up to 99%. Our tendons’ properties and functions are directly dependant of the architecture and quality of the collagen fibres.

Tendons work as an essential support in joint movement. The multiple functions of tendons consist of attaching muscles to bones, joining and stabilizing skeleton joints, and transmitting muscular force to bone pieces. Tendons also allow muscles to be at an optimal distance from the joint.

Therefore, tendons, together with muscles and bones, form a unique team that constantly work in synergy. The decrease of collagen with aging weakens the area where tendons are attached to the bone, creating a more fragile area, which frequently is the cause of many injuries. For example, a common problem known as tendinitis or tendinosis is frequently linked to a lack of collagen.

Tendinitis is an inflammation of the tendons. It has frequently been considered as the cause of tendon pain and loss of force and movement. More recently, researchers have discovered that most people diagnosed with this disease have no sign of tendon inflammation. As a result, medical science has come to consider tendinitis more as tendinosis. Nowadays, both terms are used to describe the same condition. Tendinosis or tendinitis is caused by a lack of collagen in tendons’ tissues.

Collagen contributes to keep the structure and force of tendons. When collagen is broken down, small tears appear in the tendon, weakening it and causing pain. Tendinitis specially affects those who perform repetitive tasks in their jobs, sports or daily activities. Another example of a diseaserelatedtotendonsisbursitis.Bursitisistheswellingofthebursa,asmallfluid-filledsacthat allows muscles to glide easily over the other muscles and bones. When you hurt a joint or tendon or when you use it too much, the bursa swells causing pain, redness and burning.

Theregionsmostcommonlyaffectedbybursitisaretheshoulders,elbowsandhips.Peoplewho suffer from this disease will feel pain, tenderness and stiffness near the affected area. Consequently, certain muscles weaken because the person avoids painful movements such as climbing stairs. Whether it is tendinitis or bursitis, applying ice over the painful areas and letting the painful joint rest can successfully treat these two illnesses. A hydrolyzed collagen supple-ment can also be used as nutritional support.

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Tendonselastic bandsact as of the

body

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collagenligaments

The role of

in

Ligaments are short strands of fibrous conjunctive tissue rich in collagen (almost 80%), forming an extremely solid structure with multiple functions.

Among other functions, ligaments connect bones at the joints, but they do not attach bones to muscles, as tendons carry out this function. Certain ligaments are responsible for joint mobility, avoiding false movements. This protects the integrity of joints when there is a sprain, and protects from dislocations when there is a forced movement (hyperflexion or hyper-extension). Similarly, there is a complex system of eight ligaments that reinforces the knee bones to form a very resistant joint capsule.

Ligaments also serve to join several organs to the abdominal wall and other organs between each other, as the stomach and the spleen.

Moreover, ligaments are very important to chew food, holding teeth and jawbones, facilitating the movement. As collagen decreases with time, our ligaments lose resistance, elasticity and flexibility, which can cause a frequent sensation of stiffness in our joints.

Ankles, knees and wrists are the most vulnerable joints to ligament injuries and common sprains which are generally caused by stretching or tearing one or more joint ligaments. The principal symptoms of a sprain are pain, swelling and difficulty to move the joint.

© Monkey Business Images, 2013, with the authorization of shutterstock.com

force des muclesLa

ses tissusdépend de

The human body has more than 650 muscles, making up 40% of the body’s weight.

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Muscles are made up of cells intertwined by a conjunctive tissue that works as support. This tissue, rich in collagen, is one of the main constituents of the muscular tissues that surround the muscle fibre in which its role is to support and protect. Collagen is an integral part of a system that works as a link between the internal and external part of muscular cells. This fixation system between the two environments allows the muscular cells to adapt to the mechanical deformations they undergo when there is a muscular contraction.

Given that the aging phenomenon leads to a reduction in the production of collagen, the link between the external and internal part of the muscular cell is also reduced, causing deterioration and weakening of muscles as a whole over the years. This situation affects the muscular tissue and reduces the muscle potential of carrying out their essential roles.

One of the diseases related to a reduction of collagen in muscles is fibromyalgia. Its diagnosis has been erroneous for a long time due to a lack of knowledge concerning the underlying physiopathology of this disease and the lack of specific biochemical markers to diagnose it. According to the research and standards of the American College of Rheumatology, several samples (muscular biopsy, urinary and blood dosage) have precisely led to the discovery of a deficit of collagen in those people suffering from fibromyalgia.

This deficit not only showed a lower amount of intramuscular collagen, it also showed a restructuring of the extracellular matrix with a collagen deposit around the nerve fibres. As a result, there is a decrease in the threshold of muscular microtraumatisms and a decrease in the pain threshold in the tender points.

During a clinical study carried out with fibromyalgia patients, pain was reduced in some people and had considerably been reduced in some others after taking a “hydrolyzed collagen” for a period of two to fifteen years.

Muscle strengthmuscular tissuedepends

on

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More than 90% of skin’s dermis is collagen.

Fibroblast cells in our body produce collagen, which is the base molecule that holds our skin together. With aging, the decrease in collagen production generates a loss of hydration and skin thinning which lead to the appearance of wrinkles.

Gradually, the capillary tissues in the skin become thicker and less efficient, reducing the skin’s ability to retain nutrients and water. Since skin is less healthy, there is a greater risk for it to develop stretch marks, brown spots and infections, as it no longer has the ability to work as a barrier against bacteria and viruses.

The body’s collagen production in the skin begins to decrease around the age of thirty. This process starts speeding up in our forties. Many studies have shown that our natural production of collagen could decrease at a rate of 1% per year after the age of thirty. So, by the time a person reaches 55,theycouldlose25%oftheircollagenproductioncapacity.Bytheageof70,thelosswouldbeover 40%.

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Collagenaesthetics

and

muscular tissue

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Research has proven that a great part of the metabolic work essential to repair the body takes place when we sleep. Sleep is divided into several phases or stages. Our body recovers during phases two and three of sleep, but generally, it works more during the first phase, called Alpha. Thus, it is during the Alpha phase that our body has its full capacity to regenerate. During this phase, our system looks for available collagen amino acids and other important nutrients to transform them into essential elements for our body. The sleep cycle repeats in the same manner over many hours and we go through most sleep phases several times during one night. The secret to build or repair the parts of the body consists in the ability to convert collagen into other necessary resources.

Therefore, in order to strengthen muscles, tendons, ligaments and cartilage, and to regenerate the organs and skin, the body has to go through a process of protein synthesis, which takes place precisely during the Alpha phase. Unfortunately, the protein synthesis is less efficient with aging and the regeneration process is slower. Collagen proves to be an excellent nutritional supplement for the body, as it supplies it with the sequences of amino acids that support the regeneration and synthesis of new proteins during sleep. Certainly, sleep is the base of regeneration and it is essential to our health.

Conclusion :Bettersleepequalsbetterrecovery.

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Refreshing sleepSleep is not an interruption of activity in the body; it is just another form. It is indispensable for recovery.

© Yuri Arcurs, 2013, with the authorization of shutterstock.com

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Tendinitissportsan

d

Sleep is not an interruption of activity in the body; it is just another form. It is indispensable for recovery.

According to the International Olympic Committee (IOC), it is estimated that the number of consultations in the world due to musculoskeletal (tendons, muscles, bones) sports injuries is higher than 100 million per year, 50% of which are tendons and ligaments.

The IOC states that these injuries lead to an important decrease in sports performance, reduce the functional capacities at work, and have a negative influence in the exercising ability of the general population. A high percentage of these injuries is difficult to treat and many people suffer from pain and dif-ficulties in the long term.

Whether we practice sports occasionally or professionally, the cause of most in-juries becomes apparent during the three following actions:

•Intenserepetitivemovements

•Overworking,leadingtoa weakeningofbones,cartilage, tendons, ligaments and muscles

•Badwarm-uptechniquesbeforetraining

Available research demonstrates that when practicing sports, the massive pressure on your joints is the main cause of two phe-nomena: it dehydrates tissues, rendering them more vulnerable and it increases the risk of traumatism. Therefore, all the sports consisting of repetitive movements and sudden high-speed stops can cause damage. Thus, when there is an impact, tendons, ligaments, mus-cles and cartilage may present fissures mainly on the surface of joint tissues, generating weaker scarred tissues.

The unique manufacturing procedure, called AminoLock® Sequence Technology, is an exclusive approach developed by the research and development department of Genacol Group and consists of an enhancement of the amino acids of collagen. Genacol® is manufactured respecting the highest biotechnological standards and complies with all the government requirements.

A collagen matrix is a safe, formulated substance that stimulates the production of different kinds of collagen in the body. The collagen matrix, formulated from pure collagen, produces exceptional results in the human body when used on a regular basis. Genacol® is a unique protein complex and no other collagen product on the market contains this concentration of specific amino acids.

•Aftertwelveyearsofretail success, Genacol® has becomeoneofthebest-selling naturalproductsinQuebec.

•Genacolproductsare internationallyavailablein aboutfortycountries.

•GenacolGroupwona Mercadorin2008.

•GenacolGroupisthehealth companythathasshownthe greatestgrowthinCanada, accordingtoProfit100from 2004to2009(andobtained the28thpositionwithinallthe Canadian companies)!

•GenacolGroupwasafinalist inthecontestLesMercuriades in2011.

•GuyMichaud,Presidentof GenacolGroup,wasnamed EntrepreneuroftheYear2010 in the health area, according to the Ernst & Young Entrepreneurship International Contest.

•GenacolGroupwasafinalistin the contest ‘’Grand Prix Desjardins at the international’’ in2011.

•In2012,theMichaudfamily receivedanawardgivento familybusinessesthatpossess great values.

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Success without boundariesGenacol :

Genacol is a hydrolyzed collagen, created by a unique enzymatic process. This process is called the AminoLock® Sequence Technology.

20

Success without boundaries

Clinical studiesGenacol :

As such, two independent studies have scientifically confirmed that Genacol helps reduce joint pain.

These two trials, one carried out at the University of Liège (200 subjects), and the other one at the Veterans Memorial Medical Center Institution (113 subjects), have shown positive results. With Genacol, a “statistically significant” beneficial effect with relation to pain was observed in the subjects: the best result that can be obtained during a clinical trial.

ThestudycarriedoutattheUniversityofLiegebyDr.OlivierBruyèrefromtheDepartmentofPublicHealth, Epidemiology and Health Economics: ‘‘Effect of collagen hydrolysate in articular pain: A 6-month randomized, double-blind, placebo controlled study’’ has just been published in the journal Complementary Therapies in Medicine. To consult the abstract of the study, please visit our Website.

Both trialshaveconfirmed the resultsofseveralotherstudiescarriedout in thepast; revealing the beneficial effects of certain nutrients regarding joint health. Up to now, hydrolyzed collagen proves to be one of the most promising nutritional products.

The Genacol Group continuously invests in medical research to demonstrate the beneficial health effects of its products.

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Original FormulaGenacol

Genacol Original Formula is a bioactive complex of hydrolyzed collagen; scientifically proven by two published clinical studies (available on our website). Genacol is a safe substance that offers a supply of the necessary elements in order to nutritionally support the body’s efforts in the formation of collagen. In addition, Genacol Original Formula is a supplement that helps in the formation of conjunctive tissue; as well as in the development and maintenance of cartilage. Genacol Original Formula shows outstanding results in the human body when used regularly.

Our unique formula includes a complex of several amino acid sequences conceived by using The AminoLock Sequence Technology developed exclusively by Genacol Canada Corporation Inc.

We recommend taking Genacol Original Formula to people who:

•Wanttomaintainhealthycartilage

•Sufferfromjointpain(suchasin the knee, the hip, the fingers and so on)

•Sufferfromlimitedmovements

•Havediseasesthatcausejointinflammation

•Haveasportsinjury

•Sufferfromoverworkedjoints

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InstantGenacol

Genacol Instant is a natural anti-inflammatory topical gel of high quality that contains Arnica extract and Genacol microbeads. When you gently massage the painful area with Genacol Instant; the ingredients contained in the product favor a quick and in depth relief of muscular and joint pain.

One of the ingredients used in Genacol Instant, Arnica, is a plant that has been used in Europe for decades to fight pain. During clinical trials, it has revealed similar results to anti-inflammatory products available over the counter. Used to help relieve pain and /or inflammation of the muscles and joints (e.g sprains, bruises and joint pain).

We recommend the usage of Genacol Instant to people who:

•Wantquickrelieffrompainand/orinflammationof themusclesandjoints(suchassprains,bruises, joint pain).

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-STUDiO, 2013, with the authorization of shutterstock.com

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PlusGenacol

GenacolPlus iscomposedofGenacol’sbioactivecomplexofhydrolyzedcollagenaswell asglucosamine hydrochloride; which helps maintain joint health. In addition to contributing in the maintenanceofhealthycartilage,GenacolPlusimprovesthequalityofthesynovialfluid.

Sincetheproductionofcollagenandglucosaminenaturallydiminishwithage,theGenacolPlussupplement is important for people who have joint problems.

WerecommendtakingGenacolPlustopeoplewho:

•Wanttomaintainhealthycartilage

•Sufferfromjointpain(suchasinthe knee, the hip, the fingers and so on)

•Sufferfromlimitedmovements

•Havediseasesthatcausejointinflammation

•Haveasportsinjury

•Haveoverworkedjoints

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Fast ActionGenacol

Genacol Fast Action is a revolutionary 100% natural anti-inflammatory that can help reduce inflammation and relieve joint pain. This product has been created with a secret formula offered by our research laboratory. Genacol Fast Action contains Curcuma. Research has shown that this ingredient is a safe bioactive component that is recognized for its potent anti-inflammatory activity. Genacol Fast Action is a natural alternative without the long term side effects of pain medication and is made to help decrease throbbing aches and pains! The active ingredients found in Genacol Fast Action have revolutionary and efficient capabilities in targeting inflammation and easing away pain. This can certainly play a positive role in improving one’s quality of life and physical condition.

We recommand taking this product for at least 2 to 6 weeks for optimal results.

Genacol offers natural alternatives that can lead to a healthier and pain free life; because we believe individuals deserve the absolute best for their health. Genacol Fast Action is gentle and safe for the stomach, like all other products from the Genacol brand! The next time you experience pain; Genacol Fast Action is a natural and effec-tive choice. Get back to living the best life you can pain free!

We recommend taking Genacol Fast Action to people who have:

•Diseasesthatcause jointinflammation

•Sportinjuries

•Overworkedmuscles and joints

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aridav, 2013, with the authorization of shutterstock.com

WEEKS OF DAILY USAGE

OptimalResults

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Triple ActionGenacol

Genacol Triple Action works in 3 big ways: it is an anti-inflammatory; it has penetrating Action and fast Action! Genacol Triple Action is a secret formula in the same family of great quality products offered by our research laboratory. Its ingredients contain 10% arnica, which is a popular medicinal plant that has been used for centuries to relieve stiffness, inflammation, muscle aches and pains.

This topical anti-inflammatory spray penetrates deeply into the skin to quickly relieve both chronic and temporarypain.Practicalandeasytouse,ithasamildscentofwintergreenthatfadesquickly.Thisproduct is designed specifically to bring fast aid to sore muscles and joints. Furthermore, it leaves no greasy residue, has no known side effects and delivers quick acting pain relief to the areas you need it most! Genacol Triple Action is a natural spray that allows you to get the most out of life!

We recommend using Genacol Triple Action to people who:

•requirereliefofachesandpainswhileonthego

•arelookingforaconvenientproductwhiletravelling

•doalotofphysicalactivity

•havestiffnessandinflammation

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•WhoshouldbetakingGenacol® products?

Since the formation of collagen decreases with age, every adult can benefit from a Genacol supplement, whether to maintain healthy joints or to promote rapid and penetrating relief of your muscle and joint pain.

•WhichGenacol® products should I take?

To target your specific needs, you can opt for one or more items in the Genacol range of products. Each product has its own properties, making it possible for you to use certain ones in combination.

Contact us or ask your pharmacist for advice; we will be able to recommend the Genacol product/products that best suit your needs.

•Howlongwillittakeformetofeeltheeffects?

With the exception of our topical products, Genacol Instant and Genacol Triple Action, which were designed to relieve pain upon application, the testimonies that we have received indicate that the majority of people noticed considerable improvement of their condition in very little time. Of course, each case is different and, according to the nature of the problem or the person’s general condition, the effects of Genacol can be felt more or less quickly.

FrequentlyAsked Questions

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•Howlongdoestheproducthavetobeusedfor?

There is no set period of use. Genacol products give the best results when they are used on a regular basis. It is advised, primarily in the case of degenerative disease, to use them continually in order to maximize the effects and to prevent discomfort-related pain from coming back. If in doubt, we recommend seeking the advice of a pharmacist.

•Whatistheidealdosagetotake?

Refer to the packaging or visit our website to learn about the recommended dosage of each Genacol product.

•IsGenacoleasilyabsorbedbythebody?

Yes, absolutely! Thanks to its enzymatic approach and its AminoLock® Sequence Technology, which reduces molecular weight, Genacol allows even more efficient intestinal absorption.

•Whatarethecontraindications?

We do not have sufficient information to recommend collagen consumption for women who are pregnant or breastfeeding. It is better to seek the advice of a pharmacist first.

Refer to the packaging or visit our website to learn about the contraindications of each Genacol product.

•Whataretheadversereactions?

Taking Genacol has not produced any known adverse reactions to date. If in doubt, we recommend seeking the advice of a pharmacist.

Refer to the packaging or visit our website to learn about the warnings and precautions with regard to each Genacol product.

•CanItakeGenacol®whiletakingothermedicationsorsupplements?

There is no known medicinal interaction, except with Genacol Fast Action, for which we recommend seeking the advice of a pharmacist. Genacol Original Formula and Genacol Plus are both primarily concentrated complex proteins, also considered to be nutritional supple-ments. However, it is always better to wait two hours between taking your medication and any all-natural product.

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•WhatdoesAminoLock®SequenceTechnologymean?

AminoLock® Sequence Technology generates a concentrate of amino acid sequences by the principle of selection. This method is an exclusive approach developed by our Research and Development Division, which consists of enhancing amino-peptides from collagen according to the highest biotechnology manufacturing standards. This method offers excellent nutritional support to compensate for the decrease in collagen caused by the natural aging process.

Furthermore, this method makes Genacol the only product on the market that offers this amino acid concentrate, with results supported by two clinical studies.

•CanIgiveGenacolsupplementstomypet?

It is indeed possible to give Genacol Original Formula to pets. One capsule can be administered daily to animals that weigh 32 kg (70 lbs) or less. For heavier animals, we recommend an extra capsule per every 32 kg (70 lbs). To obtain the best results, open the capsule and give the powder to your pet between meals (on an empty stomach). All you have to do is pour it onto a clean, dry surface, because animals generally love it! Although there is little chance of giving your pet a collagen overdose, as the body naturally eliminates any excess, it is recommended to respect the indicated dosages.

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•WheredoesthecollagenfoundinGenacolcomefrom?

The bioactive complex of hydrolyzed collagen from Genacol is produced using amino acids from hormone-free bovine. From Europe and certified by our governmental agencies, including Health Canada, they are of the highest nutraceutical standards. This collagen is hydrolyzed into smaller fragments by an enzymatic process. Thanks to our AminoLock® Sequence Technology, Genacol Corporation Canada Inc. enriches these fragments with amino acids from this collagen protein. Throughout the fabrication and extraction processes, this protein has no direct contact with animal blood or organs. Each batch undergoes in-depth and rigorous analyses carried out by an independent laboratory in order to confirm that the product is completely safe.

•Whatareaminoacids?

Amino acids are molecules that form the proteins that are essential to our body. Collagen is the most abundant protein in the human body and Genacol contains 19 of the 20 amino acids. Since the body does not always effectively synthesize protein, as is often the case, Genacol is a proven way to improve this condition. In addition, it is free of any filler agents. In other words, Genacol is an internationally proven specific amino acid complex that comes from collagen.

•Doyouhavefurtherquestions?

For more information, contact our customer service or visit our website at www.genacol.ca

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Yvan Cournoyer Professional hockey legend

Eight years ago, I heard about Genacol Original Formula. At the time, I was really skeptical about the effectiveness of natural products. However, when I started taking it, I quickly felt a difference! I had a knee injury that required surgery, and I was able to continue doing activities without too much difficulty. Not too long ago, I finally had my surgery and I have to say that Genacol allowed me to recover in a way that was satisfying! The results I got convinced me of becoming a spokesperson for Genacol and I now talk about it to as many people possible. It is always a great pleasure when people come to thank me about the great advice I gave them about using this product. My wife, who suffered from arm tendinitis, has no more pain. I truly encourage everybody who suffers from arthritis or joint pain to use this great Canadian product!

Linda Lang Hamilton,ON

My name is Linda Lang. I am 61 years old and have lived with fibromyalgia for about 18 years. The flare-ups would often send me to bed. I have tried several prescription drugs, including anti-depressants, and had no relief. Moderate exercise would sometimes help, but if the weather was damp, it made no difference. I have been taking Genacol, 3 capsules in the evening, and after finishing the 3rd bottle, I realized that I had not had a fibromyalgia flare-up since I started.

I am writing this as I start my 4th bottle, and will continue to use this product faithfully.

DeanAnderson SaultSteMarie,ON

I have been taking Genacol for 2 months now and have seen a problem that I have had for almost 30 years vanish. I played University volleyball and had to retire after my first season due to joint problems in my ankles. I have never blown out my ankles, but since grade 4 had issues which would cripple me to the point that I had to attempt to stand up and fall down 2-3 times before I could get close enough to my door to hang onto it. I always thought that it was just the high-impact sports that I played, but since I have taken Genacol I have been able to climb ladders, stand on my feet for long lengths of time and do squats in the gym without any side effects. My wife and family notice a huge difference and it has allowed me to take part in my son’s «Nerf Wars» which I would commonly have to opt out of. Genacol has changed the quality of my life to the point that I need to write you and thank you for producing this.

Sincerely,

Testimonials

For more information on the variety of Genacol® products:

Any kind of reproduction is strictly prohibited and subject to copyright infringement laws. Legal deposit: 1st trimester of 2013. National Library of Canada. National Library of Quebec.

The bibliography of the texts included in this booklet is available on our website.

1-888-240-3002 | genacol.com | /genacol

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