THE SIXTH ANNUAL

Children’s Hospital of Philadelphia Chronic Lung Disease ConferenceTuesday, March 10, and Wednesday, March 11, 2020

The Union League of Philadelphia • Philadelphia, Pa. • unionleague.orgThis 1½-day program is intended for the multidisciplinary team: physicians, nurses, respiratory therapists, occupational therapists, physical therapists, speech pathologists, social workers and dietitians who provide care for patients with CLD/BPD.

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Jeremiah, 3 months

COURSE OVERVIEWSevere chronic lung disease (CLD) of infancy, also known as bronchopulmonary dysplasia (BPD), is the most common chronic complication of premature birth. It affects approximately 25% of preterm infants with birth weights less than 1,500 grams and more than 50% of infants weighing less than 750 grams. Infants with BPD frequently require lengthy hospital stays and costly post-discharge medical care. A diagnosis of BPD is a strong predictor of long-term impairment in lung function, cardiovascular health, growth and neurodevelopment.

Management of infants with severe CLD/BPD presents a unique challenge due to its multisystem involvement and common association with multiple non-lung comorbidities. A coordinated, evidence-based, multidisciplinary approach is crucial to achieve the best outcomes for this high-risk population. Ideally, this strategy includes cohesive management between neonatal and pediatric care providers to facilitate high-level continuity of care during the transition to home and throughout the child’s life.

This multidisciplinary course is intended for physicians, advanced practice nurses, physician assistants, nurses, respiratory therapists and other members of the healthcare team such as occupational therapists, physical therapists, speech-language pathologists, dietitians and social workers who provide care for patients with CLD/ BPD and their families. This course will explore the pathophysiology, current research and key aspects of the management of severe CLD, including diagnostic and treatment options. This course will also discuss the long-term needs of infants with severe CLD, highlighting the chronic nature of this illness extending beyond the neonatal period.

GENERAL INFORMATIONThe conference will be held Tuesday, March 10, and Wednesday, March 11, 2020, at the Union League of Philadelphia. Registration will begin at 7 a.m., Tuesday, March 10. The registration fee includes continental breakfast both days, buffet lunch on Tuesday and program materials.

COURSE OBJECTIVES Upon completion of this course, participants should be able to:• Engage with experts in the field to discuss challenging

clinical cases and scientific abstracts• Discuss multidisciplinary modalities available to optimize

treatment of infants with BPD/CLD• Debate a clinical dilemma faced by clinicians caring for

infants with BPD/CLD• Identify co-morbidities that infants with CLD/BPD are at

risk for developing• Recognize the challenges parents face as they transition to

home with a medically complex child• Discuss prevention, pathogenesis and the differential

diagnosis of CLD/BPD

CALL FOR ABSTRACTS Share Your Knowledge and ExpertiseThe course directors and planning committee invite you to submit an abstract for consideration for the poster session held during the conference. Abstracts related to any aspects of the pathophysiology, prevention or clinical care of Bronchopulmonary Dysplasia or Chronic Lung Disease of Prematurity are welcomed. The top two abstracts will be invited to deliver an oral presentation.

Submission Deadline: Monday, Jan. 13, 2020 (11:59 p.m. EST)Accepted abstracts will be published in the conference syllabus. To learn more and submit an abstract, go to chop.cloud-cme.com.

Notification of Acceptance: Monday, Jan. 27, 2020

REGISTRATION FEESPhysicians .....................................................................$325 Trainees, nurses and all other members of the healthcare team ...........................................................$200

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MEETING LOCATION The Union League of Philadelphia is located on Avenue of the Arts in the heart of Center City. It is just 20 minutes from the Philadelphia International Airport and within walking distance of exclusive shopping, world-class restaurants, art museums and historical sites. The Union League of Philadelphia is one of the nation’s most historic private clubs. The league was founded in 1862 as a patriotic society to support policies of President Abraham Lincoln during the Civil War. It has hosted U.S. presidents, heads of state, industrialists, entertainers and visiting dignitaries from around the globe. It has evolved over time to become one of the most respected institutions in the country, overwhelmingly rich in history and tradition.

HOTEL ACCOMMODATIONSChildren’s Hospital of Philadelphia has reserved a block of rooms with reduced rates at The Inn at the League, 1450 Sansom St., Philadelphia, Pa. The Inn at the League has four-diamond quality hotel rooms and suites in the same building as the conference. The group rates are $225 single and double occupancy plus a 7% percent room tax. Participants are required to make their own hotel reservations by calling The Inn directly at 215-587-5570. Please mention the name of this conference when making your reservations. This special room rate will be available until Sunday, Feb. 9, 2020. After that date, reservations will be accepted on a space and rate availability basis.

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SOCIAL WORK CONTINUING EDUCATION CREDIT STATEMENTCHOP is a pre-approved provider of continuing education credits for Pennsylvania Licensed Social Workers, Marriage and Family Therapists, and Professional Counselors. Participants licensed in Pennsylvania who attend the full workshop and complete the required evaluation are eligible for 10.5 continuing education credits. Participants licensed in other states should check with local licensing boards to determine continuing education approval.

OCCUPATIONAL THERAPY ACCREDITATION STATEMENT

Children’s Hospital of Philadelphia is an approved provider of continuing

education by the American Occupational Therapy Association, Inc. 10.5 contact hours or 1.05 AOTA CEUs will be awarded to participants at the completion of the program. Assignment of AOTA CEUs does not imply endorsement of specific course content, products or clinical procedures by AOTA.

Approved Provider Number: 4878. Appropriate for Intermediate-level Occupational Therapists. Course falls under category of Occupational Therapy Process.

RESPIRATORY ACCREDITATION STATEMENTPending approval from The American Association for Respiratory Care, this conference will be eligible for 10.33 Continuing Respiratory Care Education contact hours.

The educational content of this program has been endorsed by the PSRC.

CANCELLATION AND REFUND POLICYChildren’s Hospital of Philadelphia reserves the right to cancel or postpone any course due to any unforeseen circumstances. In the event of cancellation or postponement, Children’s Hospital of Philadelphia will refund any registration fees, but is not responsible for any related costs, charges or expenses to participants, including cancellation charges assessed by airlines/travel agencies. In order to process refunds for course withdrawals, cancellation must be received in writing by Monday, March 2, 2020. Refunds will be issued for the amount of registration minus a $40 administrative fee. No refunds will be issued thereafter.

SERVICES FOR PEOPLE WITH DISABILITIESIf special arrangements are required for an individual with a disability to attend this meeting, please contact the Continuing Medical Education Department at 215-590-5263.

DRESS CODE AT THE UNION LEAGUE The dress code at the Union League (unionleague.org) is business casual, which is defined as a collared shirt and slacks for men and appropriate attire for women. Jeans, other denim wear, athletic attire, T-shirts, shorts, baseball caps or sneakers are not permitted in the Union League.

ACCME ACCREDITATION STATEMENTChildren’s Hospital of Philadelphia is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

AMA CREDIT DESIGNATION STATEMENTChildren’s Hospital of Philadelphia designates this live activity for a maximum of 11.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with their participation in the activity.

CONTINUING NURSING EDUCATION APPROVED PROVIDER STATEMENTChildren’s Hospital of Philadelphia is an approved provider of continuing nursing education by the Pennsylvania State Nurses Association, an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. This conference will provide a maximum of 11.66 continuing nursing education contact hours of which a maximum of 2.0 are pharmacology hours.

ASHA CONTINUING EDUCATION CREDITSThis program is offered for 1.15 ASHA CEUs (Intermediate level, Professional area).

Instructional Personnel Disclosures, financial and nonfinancial, can be found at chop.cloud-cme.com.

CLINICAL NUTRITION CPEU STATEMENTChildren’s Hospital of Philadelphia is a Continuing Professional Education (CPE) Accredited Provider with the Commission on Dietetic Registration (CDR). Registered Dietitians (RDs) and Dietetic Technicians (DTRs), will receive 9 continuing education credits (CPEUs) pending approval, upon completion of this course.

PHYSICAL THERAPY CEU STATEMENTApplication has been made to the New Jersey State Board of Physical Therapy Examiners and the Pennsylvania State Board of Physical Therapy Examiners.

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PROGRAM | TUESDAY, MARCH 10, 2020

7 a.m. Continental Breakfast/Registration/Hang Posters

8 a.m. Welcome, Introductions and Program Overview • William W. Fox, MD

Moderator: Huayan Zhang, MD8:15 a.m. Keynote Speaker: Eduardo Bancalari, MD • BPD 50 Years After: Changes in Pathogenesis, Opportunities for Prevention

9 a.m. Discussion/Questions

A Parent’s JourneyModerator: Erik A. Jensen, MD, MSCE9:15 a.m. BPD: A Parent’s Perspective: Insights from a Parent Who Is a Physician • Rachel Day, MD

10 a.m. Break/Visit Exhibitors

New Frontiers for Infants with Chronic Lung DiseaseModerator: Howard Panitch, MD10:30 a.m. Is It More Than BPD? Developmental and Genetic Disorders of the Lung • Lisa R. Young, MD

11 a.m. Lymphatic Flow Disorders in Neonates: Novel Imaging Techniques and New Treatment Options • Yoav Dori, MD, PhD

11:30 a.m. Discussion/Questions

11:45 a.m. Lunch/Visit Exhibitors/Posters Available for Viewing

Poster Symposium Moderator: Nicolas Bamat, MD, MSCE1 p.m. Poster viewing, authors to be present

1:30 p.m. Platform Presentations: Top 2 selected abstracts will be presented

3 p.m. Break/Visit Exhibitors

ASK THE EXPERT WORKSHOP (Bring your difficult questions for discussion.)

2 p.m. Ask the Expert: The Physician Perspective

Ask the Expert: Developmental Care Specialists Outlook

Ask the Expert: The Bedside Providers Viewpoint

• Steven H. Abman, MD Colorado Children’s Hospital

• Susan K. Lynch, MD Nationwide Children’s Hospital, Ohio

• Martin Keszler, MD Women and Infant’s Hospital of Rhode Island

• Huayan Zhang, MD Children’s Hospital of Philadelphia (CHOP) Lead

• Julia Welc, MA, CCC/SLP CHOP

• Lydia D. Rawlins, MEd, OTR/L CHOP

• Sara DellaVolpe, BS, CCLS CHOP

• Melissa Hanin, MS, OT/L Nationwide Children’s Hospital, Ohio

• Sara B. DeMauro, MD, MSCE CHOP Lead

• Jillane Downs, MS, APRN, NNP-BC Nationwide Children’s Hospital, Ohio

• Leane Soorikian, RRT-NPS CHOP

• Karen Warren, MSN, NNP-BC CHOP Lead

• Emma Bracken, RN, BSN CHOP

Moderator: Jason Z. Stoller, MD4:15 p.m. The Great Debate: Post Pyloric Feeds: Friend or Foe? • Erik A. Jensen, MD, MSCE, and Huayan Zhang, MD

5 p.m. Discussion/Questions

5:15 p.m. Closing Remarks and Adjourn • Huayan Zhang, MD, and Kathleen Gibbs, MD

CASE PRESENTATIONS: CHALLENGES AND LESSONS LEARNED (Please choose one to attend.)A B C D

3:15 p.m.

Transitioning from Preemie to Chronic CLD/BPD Ventilator Settings• Kevin Dysart, MD• Stamatia Alexiou, MD• Heidi Morris, MMS, PA-C

Interface Woes: Choosing and Maintaining Non-invasive Interfaces• Kristin McKenna, MD, MPH• Lauren A. Stracuzzi, MSN, RNC-

NIC, ACCNS-P• Shawn O’Brien RRT-NPS, RN• Joanne Patykula, MSN, CRNP,

PPCNP-BC, NNP-BC

Methods to Assess and Improve Growth in Severe CLD/BPD• Kathryn L. Maschhoff, MD, PhD• Emily Bingham, RDAP, CNSC, LDN• Beth Thomas, MHS, PA-C

How Much CPAP Do I Need? A Multidisciplinary Approach to Assessing Adequacy of Support• Kathleen Gibbs, MD• Audrey Wood, PT, MS, DPT, PCS• Kara Harris, RN, BSN• Amanda Ball, MMS, PA-C

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PROGRAM | WEDNESDAY, MARCH 11, 2020

7 a.m. Continental Breakfast

7:45 a.m. Welcome/Program Overview

Moderator: Steven H. Abman, MD8 a.m. A Multidisciplinary Approach to PH Management in the BPD and CLD Population • Alicia Grenolds, RN, MSN, CPNP

8:30 a.m. Discussion/Questions

Track I

Moderator: Dave Munson, MD

Track II

Moderator: Laura Sillers, MD

Track III

Moderator: Stephanie Murphy, MSN, RNC-NIC, PCNS-BC

Track IV

Moderator: Iyalla Peterside, MD, MCRP, FAAP

8:40 a.m.

Aersolization of Surface Active Agents for Pediatric Critical Care: Challenges and Opportunities

Speakers:Thomas Miller, PhD, MBA;William W. Fox, MD

Babies on the Move: Implementing Early Mobility in the NICU

Speakers: Sara R. DeMauro, MD, MSCE;Meghan Burkhardt, MS, OTR/L, BCP

Big Babies, Big Problems: Caring for the Older CLD Patient

Speaker: Jayne Celeste, RN, ADN

Beyond the CRIB: Navigating the Inpatient to Outpatient Transition

Speakers: Shazia Bhombal, MD;Michael C. Tracy, MD

9:10 a.m. BREAK BREAK BREAK BREAK

9:15 a.m.

Surgical Management of Patients with Chronic Lung Disease

Speaker:Pablo Laje, MD

Can We Take the Pressure Off ? An Innovative Treatment Strategy for Lymphedema in Severe Chronic Lung Disease

Speakers: Dalal K. Taha, DOElizabeth Cross, PT, DPT, MSW, CLT

Holding the Medically Fragile Infant: Benefits for the Family and Challenges for the Medical Team

Speaker: Amy G. Kelly, RN, BSN, RNC-NIC

Pharmacotherapies for Established Severe Bronchopulmonary Dysplasia

Speaker: Nicolas Bamat, MD, MSCE

BREAKOUT SESSIONS (Please choose your track.)

9:45 a.m. Break

Moderator: Kathleen Gibbs, MD10 a.m. Keynote Speaker: Kara Goss, MD • BPD and Beyond: Understanding the Late Cardiopulmonary Sequelae of Premature Birth

10:45 a.m. Discussion/Questions

Hot Topics in BPD: Developmental Pathophysiology and Pulmonary HypertensionModerator: Leif D. Nelin, MD11 a.m. The Role of the Placenta in the Pathogenesis and Management of BPD • Karen Mestan, MD

11:30 a.m. Risk Assessment and Monitoring of Chronic Pulmonary Hypertension: The Role of Echocardiography, Cardiac Catheterization and Other Imaging Strategies • Philip Levy, MD

Noon Discussion/Questions

12:15 p.m. Closing remarks and Adjourn • Huayan Zhang, MD, and Kathleen Gibbs, MD

From left: Jeremiah, 3 months, and Trey, 3 months

Unless otherwise noted, faculty is from Children’s Hospital of Philadelphia and/or the Perelman School of Medicine at the University of Pennsylvania.

COURSE DIRECTORSKathleen Gibbs, MD Medical Director, Newborn and Infant Chronic Lung Disease Program Associate Medical Director, Harriet and Ronald Lassin Newborn/Infant Intensive Care Unit (N/IICU)Attending NeonatologistAssociate Professor of Clinical Pediatrics

Kathleen A. Nilan, RNNurse CoordinatorNewborn and Infant Chronic Lung Disease Program (N/IICU)

Huayan Zhang, MDDirector, Newborn and Infant Chronic Lung Disease ProgramAttending Neonatologist, N/IICUAssociate Professor of Clinical PediatricsChief, Division of Neonatology and Center for Newborn Care Guangzhou Women and Children’s Medical Center

COURSE FACULTYStamatia Alexiou, MDAttending Physician, Division of Pulmonary MedicineAssistant Professor of Pediatrics

Amanda Ball, MMS, PA-CPhysician AssistantDivision of Neonatology

Nicolas Bamat, MD, MSCE Attending Neonatologist, N/IICU Instructor in Pediatrics

Emily Bingham, RD-AP, CNSC, LDNNeonatal Dietitian, N/IICU

Emma Bracken, RN, BSNClinical Nurse, N/IICUN/IICU Transport Team

Meghan Burkhardt, MS, OTR/L, BCPEducation and Development CoordinatorPediatric Occupational Therapy Fellowship Coordinator

Jayne Celeste, RN, ADNPeak 1 Clinical Nurse, N/IICU

Elizabeth A. Cross, PT, DPT, MSW, CLTOutpatient Physical Therapy Supervisor

Sara DellaVolpe, BS, CCLSAdvanced Child Life Specialist, N/IICU

Sara B. DeMauro, MD MSCEAttending Neonatologist, N/IICUProgram Director, Neonatal Follow-up Associate Professor of Pediatrics

Yoav Dori MD, PhD Director, Pediatric Lymphatic Imaging and Interventions and Lymphatic ResearchInterventional Cardiologist Assistant Professor of Cardiology

Kevin Dysart, MDAssociate Medical Director, N/IICUProfessor of Clinical Pediatrics

William W. Fox, MDAssociate Director, Infant Breathing Disorder CenterAttending Neonatologist, N/IICUPI, Frontier ProgramProfessor Emeritus of Pediatrics

Kara Harris, RN, BSNClinical Nurse, N/IICU

Erik A. Jensen, MD, MSCEAttending Neonatologist, N/IICU Assistant Professor of Pediatrics

Amy G. Kelly, BSN, RN, RNC-NICClinical Nurse Expert, N/IICUN/IICU Transport Team

Pablo Laje, MDAttending Surgeon, Division of General, Thoracic and Fetal Surgery

Kathryn L. Maschhoff, MD, PhDAttending Neonatologist, N/IICUAssociate Professor of Clinical Pediatrics

Kristin McKenna, MD, MPHAttending Neonatologist, N/IICUAssociate Professor of Clinical Pediatrics

Heidi Morris, MMS, PA-CDivision of NeonatologyResearch Coordinator, Newborn and Infant Chronic Lung Disease Program

Shawn O’Brien, RRT-NPS, RNSenior Respiratory Therapist

Joanne Patykula, MSN, CRNP, PPCNP-BC, NNP-BCNurse Practitioner, Division of Neonatology

Iyalla E. Peterside, MD, MRCP, FAAP Attending Neonatologist, N/IICUProfessor of Clinical Pediatrics

Lydia D. Rawlins, MEd, OTR/LAcute Care Occupational Therapy Supervisor

Leane Soorikian, RRT-NPSRespiratory Clinical Specialist, N/IICUSpecial Delivery Unit

Lauren A. Stracuzzi, MSN, RNC-NIC, ACCNS-PClinical Nurse Specialist, N/IICU

Dalal K. Taha, DOAttending Neonatologist, N/IICU and Center for Lymphatic Imaging and InterventionsAssistant Professor of Clinical Pediatrics

Beth Thomas, MHS, PA-CPhysician Assistant, Division of Neonatology

Karen Warren, MSN, NNP-BCNurse Practitioner, Division of Neonatology

Julia Welc, MA, CCC/SLPInpatient CoordinatorSpeech-Language Pathology

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Audrey Wood, PT, MS, DPT, PCSPhysical Therapist III, N/IICU

Lisa R. Young, MDDivision Chief, Division of Pulmonary MedicineJohn M. Keating Endowed Chair in Pulmonary MedicineProfessor of Pediatrics

KEYNOTE SPEAKERSEduardo Bancalari, MDProfessor of Pediatrics, Obstetrics and GynecologyDirector, Division of NeonatologyUniversity of Miami Miller School of Medicine

Kara Goss, MDAssistant Professor of Medicine and PediatricsDivision of Allergy, Pulmonary and Critical CareUniversity of Wisconsin

GUEST FACULTYSteven H. Abman, MDDirector, Pediatric Heart Lung CenterChildren’s Hospital ColoradoProfessor, Department of PediatricsUniversity of Colorado School of Medicine

Shazia Bhombal, MDClinical Associate Professor, PediatricsMedical Director, NICU Heart TeamDivision of Neonatal & Developmental MedicineStanford University School of Medicine

Rachel Day, MDMom of two former N/IICU patients with BPD

Jillane Downs, MS, APRN, NNP-BCNurse PractitionerComprehensive Center for Bronchopulmonary Dysplasia Program (CCBPD) NICU, Nationwide Children’s Hospital

Alicia Grenolds, RN, MSN, CPNPSenior InstructorThe Breathing Institute & Pediatric Heart Lung CenterChildren’s Hospital Colorado

Melissa Hanin, MS, OT/LNeonatal TherapistDevelopmental Coordinator, CCBPDNationwide Children’s Hospital

Martin Keszler, MDProfessor of PediatricsWarren Alpert Medical School of Brown UniversityAssociate Medical Director, Neonatal Intensive Care UnitDirector of Respiratory ServicesWomen & Infants Hospital of Rhode Island

Philip Levy, MDAssistant Professor, Division of Newborn MedicineDepartment of Pediatrics Harvard Medical School and Boston Children’s HospitalBoston, Mass.

Susan K. Lynch, MD Clinical Director, CCBPDNationwide Children’s Hospital, Columbus, OhioAssociate Professor of Pediatrics, Ohio State University

Karen Mestan, MDAssociate Professor, Pediatrics/NeonatologyDirector, Perinatal Origins of Disease Research ProgramLurie Children’s Hospital/Stanley Manne Children’s Research Institute of ChicagoNorthwestern University Feinberg School of Medicine

Thomas Miller, PhD, MBAVice President and Global Head, Pediatric Development, BayerWhippany, N.J.

Michael C. Tracy, MDDirector of Bronchopulmonary Dysplasia ClinicClinical Assistant Professor, Pulmonary MedicineLucile Packard Children’s Hospital StanfordStanford University School of Medicine

MODERATORSDavid Munson, MDAttending NeonatologistMedical Director, N/IICUProfessor of Clinical Pediatrics

Stephanie Murphy, MSN, RNC-NIC, PCNS-BCClinical Nurse Specialist, N/IICU

Leif D. Nelin, MD, FAAPDean W. Jeffers Chair in NeonatologyDivision Chief, Division of NeonatologyNationwide Children’s HospitalProfessor of PediatricsOhio State University

Howard Panitch, MDDirector, Technology Dependence CenterDivision of Pulmonary MedicineProfessor of Pediatrics

Laura Sillers, MDAttending Neonatologist, N/IICUAssistant Professor of Clinical Pediatrics

Jason Z. Stoller, MDAttending Neonatologist, N/IICUAssociate Professor of Clinical Pediatrics

CONFERENCE PLANNING COMMITTEESteven H. Abman, MDNicolas Bamat, MD, MSCEEmily Bingham, RD-AP, CNSC, LDNMeghan Burkhardt, MS, OTR/L, BCPKevin Dysart, MDRegina Flynn-Roth, MSN, RN-BC, Nurse PlannerKathleen Gibbs, MDKara Harris, RN, BSNErik A. Jensen, MD, MSCEKathryn L. Maschhoff, MD, PhDHeidi Morris, MMS, PA-CLeif D. Nelin, MD, FAAPKathleen Nilan, RNShawn O’Brien, RRT-NPS, RNPatti O’Connor, RN, MSIyalla Peterside, MD, MRCP, FAAPJason Z. Stoller, MDAudrey Wood, PT, MS, DPT, PCSHuayan Zhang, MD

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CONTINUING MEDICAL EDUCATION DEPARTMENT3401 Civic Center Blvd., Phila., PA 19104

ADDRESS SERVICE REQUESTED

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Attendees at the 2019 conference

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