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Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson Education, Inc.

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Page 1: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Chapter 3Mendelian Genetics

Art and Photos in PowerPoint®

Concepts of GeneticsNinth Edition

Klug, Cummings, Spencer, Palladino

Copyright © 2009 Pearson Education, Inc.

Page 2: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

http://www.mendelweb.org

Page 3: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson
Page 4: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.1

Page 5: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.1 Mendel Used a Model Experimental Approach to Study Patterns of Inheritance

Page 6: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.2 The Monohybrid Cross Reveals How One Trait Is Transmitted from Generation to Generation

Page 7: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

• Pairs of Unit Factors of Inheritance (aka “genes”)

• Dominance/Recessiveness

• Principle of Segregation

Mendel’s First Three Postulates:

Page 8: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.2

Page 9: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson
Page 10: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson
Page 11: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.3

Page 12: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Fig 3-3

Page 13: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson
Page 14: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

How can we determine the genotype of an organism displaying a dominant phenotype?

Page 15: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.2 The Monohybrid Cross Reveals How One Trait Is Transmitted from Generation to Generation

3.2.5 The Testcross: One Character

Page 16: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.4

Page 17: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.4a

Page 18: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.4b

Page 19: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.3 Mendel’s Dihybrid Cross Generated a Unique F2 Ratio

Page 20: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.5

Page 21: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.6

Page 22: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Mendel’s Dihybrid Cross Revealed His Fourth Postulate:

Independent Assortment

Page 23: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.7

Page 24: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Fig 3-7

Page 25: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Fig 3-7

Page 26: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

How many phenotypes and genotypes do you expect among the F2 generation?

Page 27: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Fig 3-7

Page 28: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.3 Mendel’s Dihybrid Cross Generated a Unique F2 Ratio

3.3.2 The Testcross: Two Characters

Page 29: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.8

Page 30: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.4 The Trihybrid Cross Demonstrates That Mendel’s Principles Apply to Inheritance of Multiple Traits

Page 31: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3-9 Copyright © 2006 Pearson Prentice Hall, Inc.

Trihybrid cross

???

Page 32: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.4 The Trihybrid Cross Demonstrates That Mendel’s Principles Apply to Inheritance of Multiple Traits

3.4.1 The Forked-Line Method, or Branch Diagram

Page 33: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.10

Page 34: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Table 3.1

Page 35: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.5 Mendel’s Work Was Rediscovered in the Early Twentieth Century

Page 36: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.6 The Correlation of Mendel’s Postulates with the Behavior of Chromosomes Provided the Foundation of Modern Transmission Genetics

3.6.1 Unit Factors, Genes, and Homologous Chromosomes

Page 37: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.11

Page 38: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.11a

Page 39: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.11b

Page 40: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.11c

Page 41: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.7 Independent Assortment Leads to Extensive Genetic Variation

Page 42: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.8 Laws of Probability Help to Explain Genetic Events

Page 43: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.9 Chi-Square Analysis Evaluates the Influence of Chance on Genetic Data

3.9.1 Chi-Square Analysis and the Null Hypothesis

Page 44: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Table 3.3

Page 45: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.12ab

Page 46: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.12a

Page 47: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.12b

Page 48: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.10 Pedigrees Reveal Patterns of Inheritance of Human Traits

3.10.1 Pedigree Conventions

Page 49: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.13

Page 50: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

3.10 Pedigrees Reveal Patterns of Inheritance of Human Traits

3.10.2 Pedigree Analysis

Page 51: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.14a

Page 52: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Figure 3.14b

Page 53: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Chapt 3, Prob 26

Page 54: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Chapt 3, Prob 27

Page 55: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Chapt 3, Prob 33

Page 56: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Tt Tt

tt

TT or Tt2/3 chance Tt

1/2 x 2/3 =1/3 chance Tt1/3 chance Tt

So, chance that child hasTay Sachs (tt)= 1/4 x 1/3 x 1/3 = 1/36

Page 57: Chapter 3 Mendelian Genetics Art and Photos in PowerPoint ® Concepts of Genetics Ninth Edition Klug, Cummings, Spencer, Palladino Copyright © 2009 Pearson

Table 3.4