chapter 23, part 1
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Chapter 23, part 1. The Respiratory System. SECTION 23-1 The Respiratory System: An Introduction. Learning Objectives. Describe the primary functions of the respiratory system Identify the organs of the respiratory system and describe their functions - PowerPoint PPT PresentationTRANSCRIPT
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Fundamentals of
Anatomy & PhysiologySIXTH EDITION
Frederic H
. Martini
PowerPoint® Lecture Slide Presentation prepared by Dr. Kathleen A. Ireland, Biology Instructor, Seabury Hall, Maui, Hawaii
Chapter 23, part 1
The Respiratory System
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
SECTION 23-1 The Respiratory System: An Introduction
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Learning Objectives
• Describe the primary functions of the respiratory system
• Identify the organs of the respiratory system and describe their functions
• Define and compare the processes of external and internal respiration
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Learning Objectives
• Summarize the physical principles governing the movement of air into the lungs and the diffusion of gases into the blood
• Explain the important structural features of the respiratory membrane
• Describe how oxygen and carbon dioxide are picked up, transported and released in the blood
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• Gas exchange between air and circulating blood
• Moving air from the exchange surface of the lungs
• Protection of respiratory surfaces
• Production of sound
• Provision for olfactory sensations
Functions of the respiratory system
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• Upper respiratory system
• Nose, nasal cavity, paranasal sinuses, pharynx
• Lower respiratory system
• Larynx, trachea, bronchi, bronchioles, alveoli
Organization of the respiratory system
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Figure 23.1 The Components of the Respiratory System
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• Conducting passageways carrying air to and from the alveoli
• Upper respiratory passages filter and humidify incoming air
• Lower passageways include delicate conduction passages and alveolar exchange surfaces
The Respiratory tract
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• Respiratory epithelium and underlying connective tissue
• Respiratory membrane, supported by lamina propria, changes along tract
• Lines conducting portion of respiratory tract
• Protected from contamination by respiratory defense system
Respiratory Mucosa
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Figure 23.2 The Respiratory Epithelium of the Nasal Cavity and Conducting System
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SECTION 23-2 The Upper Respiratory System
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• External nares
• Nasal cavity
• Vestibule
• Superior, middle and inferior meatuses
• Hard and soft palates
• Internal nares
• Nasal mucosa
The nose and nasal cavity consists of:
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Figure 23.3 The Nose, Nasal Cavity, and Pharynx
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Figure 23.3 The Nose, Nasal Cavity, and Pharynx
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• Shared by the digestive and respiratory systems
• Divided into three sections:
• Nasopharynx – superior portion
• Oropharynx – continuous with the oral cavity
• Laryngopharynx – between the hyoid bone and the esophagus
The pharynx
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SECTION 23-3 The Larynx
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• Air passes through the glottis on the way to the lungs
• Larynx protects the glottis
• Cartilages of the larynx
• Three large cartilages
• Thyroid, cricoid, and epiglottis
• Paired cartilages
• Arytenoids, corniculate, and cuneiform
The larynx
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• Inelastic vestibular folds
• Delicate vocal folds
Folds of the larynx
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Figure 23.4 The Anatomy of the Larynx
Figure 23.4
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• Air passing through the glottis vibrates the vocal folds producing sound waves
• Pitch depends on conditions of vocal folds
• Diameter
• Length
• Tension
Sound production
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Figure 23.5 The Glottis
Figure 23.5a, b
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• Muscles of the neck and pharynx position and stabilize the larynx
• When swallowing,these muscles
• Elevate the larynx
• Bend the epiglottis over the glottis
• Intrinsic muscles control tension on the vocal folds and open the glottis
The laryngeal musculature
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SECTION 23-4The Trachea and Primary Bronchi
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• Extends from the sixth cervical vertebra to the fifth thoracic vertebra
• A tough, flexible tube running from the larynx to the bronchi
• Held open by C-shaped tracheal cartilages in submucosa
• Mucosa is similar to the nasopharynx
The trachea
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Figure 23.6 The Anatomy of the Trachea
Figure 23.6a, b
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Figure 23.6 The Anatomy of the Trachea
Figure 23.6c
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• Trachea branches in the mediastinum into right and left bronchi
• Bronchi enter the lungs at the hilus
• Root = the connective tissue mass including:
• Bronchus
• Pulmonary vessels
• Nerves
The primary bronchi
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SECTION 23-5 The Lungs
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• Lobes of the lung are separated by fissures
• Right lung has three lobes
• Left lung has two lobes
• Concavity on medial surface = cardiac notch
Lobes and surfaces of the lungs
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Figure 23.7 The Gross Anatomy of the Lungs
Figure 23.7
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Figure 23.7 The Gross Anatomy of the Lungs
Figure 23.7
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Figure 23.7 The Gross Anatomy of the Lungs
Figure 23.7
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Figure 23.8 The Relationship between the Lungs and the Heart
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• System of tubes formed from the primary bronchi and their branches
• Primary bronchi branch into secondary or lobar bronchi
• Secondary bronchus goes to each lobe of the lungs
• Secondary bronchi branch into tertiary bronchi
• Tertiary bronchi supply air to a single bronchopulmonary segment
• Cartilage in walls decrease and smooth muscle increase with branching
The bronchial tree
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Figure 23.10 The Bronchi and Lobules of the Lung
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Figure 23.10 The Bronchi and Lobules of the Lung
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• Ultimately branch into terminal bronchioles
• Delivers air to a single pulmonary lobule
• Terminal bronchiole becomes respiratory bronchioles
• Connective tissue of root branches to form interlobar septa
The bronchioles
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• Respiratory bronchioles end in ducts and sacs
• Respiratory exchange surfaces connected to circulatory system via pulmonary circuit
Alveolar ducts and alveoli
Animation: Lungs FlythroughPLAY
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Figure 23.11 The Bronchioles
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• Simple squamous epithelium
• Endothelial cell lining an adjacent capillary
• Fused basal laminae
Respiratory Membrane
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• Septal cells
• Scattered in respiratory membrane
• Produce surfactant
• Alveolar Macrophage
• Patrol epithelium and engulf foreign particles
Cells of the respiratory membrane include
Animation: Respiratory StructuresPLAY
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Figure 23.12 Alveolar Organization
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• Conducting portions
• Receive blood from external carotids, thyrocervical, bronchial arteries
• Respiratory exchange surfaces
• receive blood from the arteries of the pulmonary circuit
• are the source of angiotensin-converting enzyme (ACE)
• Pulmonary veins return blood to the left atrium
The blood supply to the lungs
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• Each lung covered by one pleura
• Pleura – serous membranes lining the pleural cavity
• Parietal - attaches to the walls of the pleural cavity
• Visceral - adheres to the surface of the lungs
• Pleural fluid – fills and lubricates the space between the pleura
The pleural cavities and pleural membranes
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SECTION 23-6 An Overview of Respiratory Physiology
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• Internal respiration
• Exchange of gases between interstitial fluid and cells
• External respiration
• Exchange of gases between interstitial fluid and the external environment
• The steps of external respiration include:
• Pulmonary ventilation
• Gas diffusion
• Transport of oxygen and carbon dioxide
Respiratory physiology is a series of integrated processes
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Figure 23.13 An Overview of Key Steps in Respiration
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SECTION 23-7 Pulmonary Ventilation
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• The physical movement of air into and out of the lungs
Pulmonary Ventilation
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• Movement of air depends upon
• Boyle’s Law
• Pressure and volume inverse relationship
• Volume depends on movement of diaphragm and ribs
• Pressure and airflow to the lungs
• Compliance – an indication of the expandability of the lungs
Air movement
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Figure 23.14 Respiratory Pressure and Volume Relationships
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• Relationship between intrapulmonary pressure and atmospheric pressure determines direction of air flow
• Intrapleural pressure maintains pull on lungs
• Pressure in the space between parietal and visceral pleura
Pressure changes during inhalation and exhalation
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Figure 23.15 Mechanisms of Pulmonary Ventilation
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Figure 23.15 Mechanisms of Pulmonary Ventilation
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• Single cycle of inhalation and exhalation
• Amount of air moved in one cycle = tidal volume
Respiratory cycle
Animation: Pulmonary VentilationPLAY
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Figure 23.16 Pressure Changes during Inhalation and Exhalation
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• Quiet breathing (eupnea)
• Diaphragm and external and internal intercostals muscles
• Forced breathing (hyperpnea)
• Accessory muscles
Mechanisms of breathing
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Figure 23.17 The Respiratory Muscles
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• Alveolar volume
• Amount of air reaching the alveoli each minute
• Tidal Volume (VT)
• Amount of air inhaled or exhaled with each breath
• Vital capacity
• Tidal volume plus expiratory and inspiratory reserve volumes
• Residual volume
• Air left in lungs after maximum exhalation
Respiratory volumes
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Figure 23.18 Respiratory Volumes and Capacities
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SECTION 23-8 Gas Exchange
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• Daltons Law and partial pressure
• Individual gases in a mixture exert pressure proportional to their abundance
• Diffusion between liquid and gases (Henry’s law)
• The amount of gas in solution is directly proportional to their partial pressure
The gas laws
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Figure 23.19 Henry’s Law and the Relationship between Solubility and Pressure
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Figure 23.19 Henry’s Law and the Relationship between Solubility and Pressure
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• Gas exchange across respiratory membrane is efficient due to:
• Differences in partial pressure
• Small diffusion distance
• Lipid-soluble gases
• Large surface area of all alveoli
• Coordination of blood flow and airflow
Diffusion and respiratory function
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
Fundamentals of
Anatomy & PhysiologySIXTH EDITION
Frederic H
. Martini
PowerPoint® Lecture Slide Presentation prepared by Dr. Kathleen A. Ireland, Biology Instructor, Seabury Hall, Maui, Hawaii
Chapter 23, part 4
The Respiratory System
Copyright © 2004 Pearson Education, Inc., publishing as Benjamin Cummings
SECTION 23-9 Gas Pickup and Delivery
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• Reactions are completely reversible
Blood in peripheral capillaries delivers O2 and absorbs CO2
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Animation: Respiratory Processes and Partial Pressures in RespirationPLAY
Figure 23.20 An Overview of Respiratory Processes and Partial Pressures in Respiration
Figure 23.20a, b
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• Carried mainly by RBCs, bound to hemoglobin
• The amount of oxygen hemoglobin can carried is dependent upon:
• PO2
• pH
• temperature
• BPG
• Fetal hemoglobin has a higher O2 affinity than adult hemoglobin
Oxygen transport
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Figure 23.21 The Oxygen-Hemoglobin Saturation Curve
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Figure 23.21 The Oxygen-Hemoglobin Saturation Curve
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Figure 23.22 The Effect of pH and Temperature on Hemoglobin Saturation
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Figure 23.23 A Functional Comparison of Fetal and Adult Hemoglobin
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• 7% dissolved in plasma
• 70% carried as carbonic acid
• buffer system
• 23% bound to hemoglobin
• carbaminohemoglobin
• Plasma transport
Carbon dioxide transport
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Figure 23.24 Carbon Dioxide Transport in Blood
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Figure 23.24 Carbon Dioxide Transport in Blood
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• Driven by differences in partial pressure
• Oxygen enters blood at lungs and leaves at tissues
• Carbon dioxide enters at tissues and leaves at lungs
Summary of gas transport
Animation: Gas Exchange and Gas TransportPLAY
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Figure 23.25 A Summary of the Primary Gas Transport Mechanisms
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• The primary functions of the respiratory system
• The organs of the respiratory system and their functions
• The processes of external and internal respiration
• The physical principles governing the movement of air into the lungs and the diffusion of gases into the blood
• The important structural features of the respiratory membrane
• How oxygen and carbon dioxide are picked up, transported and released in the blood
You should now be familiar with: