causes of nasal mass- joe
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CAUSES OF NASALMASS
Joseph Lim071303503
Group A1 Batch 22
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Causes of Nasal Mass
Congenital
Dermoid cysts
Glioma
Encephalocele
Acquired
Neoplastic Non-neoplastic
Benign Malignant
Invertedpapilloma
Juvenilenasopharyngeal
angiofibroma Squamous
papilloma Chondroma Haemangioma Rhinophyma
Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma Olfactory
neuroblastoma Hemangiopericytom
a Plasmacytoma
Nasal polyps Granulomas Traumatic Rhinolith
Causes of Nasal Mass
Congenital
Dermoid cysts
Glioma
Encephalocele
Acquired
Neoplastic Non-neoplastic
Benign Malignant
Invertedpapilloma
Juvenilenasopharyngeal
angiofibroma Squamous
papilloma Chondroma Haemangioma Rhinophyma
Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma Olfactory
neuroblastoma Hemangiopericytom
a Plasmacytoma
Nasal polyps Granulomas
Rhinolith
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Congenital
Dermoid cysto Simple dermoid: Midline swelling under the skin in front of the
nasal bone
o Associated with sinus: Midline swelling on the dorsum of nose
with an external opening (sinus). Hair may seen protruding
through the sinus. Sinus track can go under nasal bone orintracranial dural - meningitis
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Gliomaso Firm subcutaneous swelling on bridge, side of nose or near
inner canthuso Nipped off portion of encephalocele during embryonic
development
o Occur in infants & children - 60% are extranasal
o
Firm, non compressible and size does not increase on crying,no transillumination and telangiectasis on skin
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Extranasal Encephalocele/ Meningoencephaloceleo Subcutaneous pulsatile swelling in the midline at the root of the
nose (nasofrontal), side of nose (nasoethmoid) or on theanteromedial aspect of orbit (naso-orbital)
o Herniation of brain tissue & meninges through a congenital bony
defect
o Smooth, mobile, easily compressible, enlarges on crying, shows
cough impulse and may be reducibleo Contains CSF and sometimes cerebral tissue
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Causes of Nasal Mass
Congenital
Dermoid cysts
Glioma
Encephalocele
Acquired
Neoplastic Non-neoplastic
Benign Malignant
Invertedpapilloma
Juvenilenasopharyngeal
angiofibroma Squamous
papilloma Chondroma Haemangioma Rhinophyma
Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma Olfactory
neuroblastoma Hemangiopericytom
a Plasmacytoma
Nasal polyps Granulomas
Rhinolith
Causes of Nasal Mass
Congenital
Dermoid cysts
Glioma
Encephalocele
Acquired
Neoplastic Non-neoplastic
Benign Malignant
Invertedpapilloma
Juvenilenasopharyngeal
angiofibroma Squamous
papilloma Chondroma Haemangioma Rhinophyma
Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma Olfactory
neuroblastoma Hemangiopericytom
a Plasmacytoma
Nasal polyps Granulomas Traumatic Rhinolith
Foreign
bodies
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Non-Neoplastic
1. Nasal polyp
o Non neoplastic masses of edematous, prolapsedmucosa of paranasal sinus/nasal cavity
o Round, pedunculated, fleshy , grape-like mass which is
greyish/bluish white translucent in colour with smooth
glistening surfaceo Soft, mobile, insensitive, and does not bleed on touch
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Aetiology
o Chronic rhinosinusitis
o Asthmao Aspirin intolerance
o
Cystic fibrosiso Allergic fungal sinusitis
o Kartageners syndrome
o Youngs syndrome
o Churg-Strauss syndromeo Nasal mastocytosis
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Pathology
o End product of prolonged odemao Submucosa especially around middle meatus is lax
and is easily water logged
o
Increase vascular permeability fluid retention(odema) prolapse of mucosa
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Antrochoanal v/s Ethmoidal
Pathology
o Arises frommaxillary antrum
o Usually unilateraland solitary
o Arises fromethmoid sinuses
o Bilateral due toallergy
o Multiple due to
multiple ethmoidair cells (8-20)
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Antrochoanal v/s ethmoidal
Clinical features- Symptomso Childreno Unilateral nasal
obstruction Valvular
o Bilateral if opposite
choana is blocked in
nasopharynx
o Unilateral nasaldischarge-mucoid/mucopurulent
o No allergy symptoms
o Middle aged
Exception: in cystic
fibrosis/ mucovisidosisoccurs in children
o Allergy symptoms+
o Bilateral nasal
obstruction/dischargeo Anosmia
o Asthma/ aspirinintolerence
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Antrochoanal v/s ethmoidalClinical features: Signs
o Solitary and unilateralo Seen more postnasally
than anteriorly
o External: Frog-facedeformity +/-(intercanthal widening)
o Multiple and bilateralo Seen more anteriorly
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Tuberculosis
Lupus vulgaris
Sarcoidosis
Leprosy
Rhinoscleroma
Foreign bodyoreosinophilicgranuloma
Idiopathic
Wegenersgranulomatosis
Stewarts
granuloma
Fungal
Rhinosporidiosis
Spirochetal
Syphilis
Bacterial
Granulomatous
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Rhinoscleroma Caused by Klebsiella rhinoscleromatis
(gram negative bacilli)
Starts in the nose, extends tonasopharynx, oropharynx, larynx,
trachea, and bronchi. 3 stages :
Atrophic stage: foul smellingpurulent discharge
Granulomatous stage: painless andnon-ulcerative nodules form in nasal
mucosa, lips and external nose
Hebra nose, woody feeling
Cicatricial stage: Stenosis of nares,
distortion of upper lip, adhesion in
the nose, nasopharynx, and
oropharynx.
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Rhinosporidiosis
Caused by yeast like fungi
Rhinosporidium seeberi A leafy, polypoidal mass, pink
to purple in colour, attached to
nasal septum and lateral wall
Surface is studded with whitedots sporangia of fungus
Strawberry appearance
Vascular and bleeds on touch
May extend to nasopharynx
and hang behind soft palate
Nasal discharge blood
tinged, epistaxis
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3. Traumatic:
Septal haematoma Collection of blood under the perichondrium or periosteum
of the nasal septum Smooth soft rounded swelling of the septum in both the
nasal fossae Bilateral nasal obstruction, frontal headache
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Septal abscess
Results from secondary infection of septal haematoma/
follows furuncle of nose/upper lip Smooth bilateral swelling of the nasal septum
Severe bilateral nasal obstruction Pain and tenderness over the bridge of nose.
May associated with fever with chills, frontal headache Congested septal mucosa Enlarged submandibular lymph nodes
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4. Rhinolith Stone formation in the nasal
cavity Deposition of Ca and Mg salts
around the nucleus of a small
exogenous foreign body,
blood clot or inspissatedsecretion.
Pressure necrosis of
septum/lateral wall.
Unilateral nasal obstruction,foul smelling and blood-
stained discharge.
Grey /greenishmassirregular surfacestony hard
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Foreign bodies
If a child presents with unilateral, foul smelling nasaldischarge, foreign bodies must be excludedAetiology:
pieces of paper, chalk, button, pebbles, seed
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Causes of Nasal Mass
Congenital
Dermoid cysts
Glioma
Encephalocele
Acquired
Neoplastic Non-neoplastic
Benign Malignant
Invertedpapilloma
Juvenilenasopharyngeal
angiofibroma Squamous
papilloma Chondroma Haemangioma Rhinophyma
Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma
Olfactoryneuroblastoma
Hemangiopericytoma
Plasmacytoma
Nasal polyps Granulomas
Rhinolith
Causes of Nasal Mass
Congenital
Dermoid cysts
Glioma
Encephalocele
Acquired
Neoplastic Non-neoplastic
Benign Malignant
Invertedpapilloma
Juvenilenasopharyngeal
angiofibroma Squamous
papilloma Chondroma Haemangioma Rhinophyma
Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma
Olfactoryneuroblastoma
Hemangiopericytoma
Plasmacytoma
Nasal polyps Granulomas Traumatic
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Benign Neoplastic
Inverted papilloma
Benign but locally aggressive premalignant tumor of thenasal cavity
Pedunculated grey or reddish mass arise from the lateral
nasal wall, usually in the region of the middle meatus and
turbinate
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Symptoms Elderly males, 4070 years old
Unilateral nasal obstruction
Blood stained nasal discharge
Epistaxis
Pain, epiphora, proptosis +/-
H/O multiple previous nasal polypectomy+/-
Signs Reddish, vascular, firm, mobile, insensitive
pedunculated mass from lateral nasal wall
Looks like unilateral infected polyp May bleed on probing
Proptosis, facial swelling especially if associated with
malignancy
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Histologically benign yet locally
aggressive tumour ofnasopharynx seen in adolescentboys
Exact cause is unknown
testosterone dependent? Site: posterior part of nasal cavity
close to sphenopalatine foramen
Made of vascular and fibrous
tissue The vessels have a single endothelial cell lining without a
muscle coat, which probably explains the tumor's
propensity for hemorrhage; no muscle, cant contract.
Juvenile Nasopharyngeal Angiofibroma (JNA)
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Symptoms Adolescent males; 14-18 years
Nasal obstruction, nasal discharge (80%)
Profuse, painless, unprovoked paroxysms of epistaxis (60%) Less common symptoms include hearing loss, anosmia,
mouth breathing, diplopia and blindness
Signs Lobulated, firm, non-encapsulated mass, pink-gray or
purple-red in colour, Sessile or pedunculated
Probe test: CONTRAINDICATED
Proptosis, palatal bulge, or swelling of the cheek or over the
zygoma- Ominous indications of extensive tumor spread -tumor extension well beyond the nasopharynx.
Otitis media
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Intranasal meningoencephalocoele
o Herniation of brain tissue and meninges through
foramen caecum or cribriform plate
o Present as smooth polyp in upper part of nose
between septum and middle turbinateo Usually in infant and young children
o Misdiagnosed as simple polyp excise
meningealand brain damage
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Squamous papilloma Similar to skin wart Can arise from nasal vestibule or
lower part of nasal septum Maybe single /multiple,
pedunculated/sessile
Rhinophyma Slow-growing tumour, due to
hypertrophy of the sebaceousglands of the tip of external nose
Pink, lobulated mass over thenose with superficial vasculardilation.
seen in the long standing case ofacne rosacea
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Haemangioma
Soft, dark red, pedunculated orsessile tumour
Chondroma Arise from ethmoid, nasal cavity or
nasal septum. Pure chondromas are smooth, firm
and lobulated.
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Causes of Nasal Mass
Congenital
Dermoid cysts
Glioma
Encephalocele
Acquired
Neoplastic Non-neoplastic
Benign Malignant
Invertedpapilloma
Juvenilenasopharyngeal
angiofibroma Squamous
papilloma Chondroma Haemangioma Rhinophyma
Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma
Olfactoryneuroblastoma
Hemangiopericytoma
Plasmacytoma
Nasal polyps Granulomas
Rhinolith
Causes of Nasal Mass
Congenital
Dermoid cysts
Glioma
Encephalocele
Acquired
Neoplastic Non-neoplastic
Benign Malignant
Invertedpapilloma
Juvenilenasopharyngeal
angiofibroma Squamous
papilloma Chondroma Haemangioma Rhinophyma
Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma
Olfactoryneuroblastoma
Hemangiopericytoma
Plasmacytoma
Nasal polyps Granulomas Traumatic
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Malignant neoplastic
Carcinoma of nasal cavity
Squamous cell carcinoma (80%) Vestibular Septal Lateral wall
Adenocarcinoma and Adenoid cystic carcinoma
Gland of mucous membrane or minor salivary glandsMalignant melanoma
Malignant tumor of melanocytes, >50 years old Slate grey or bluish black polypoid mass
Site usually at anterior part of nasal septum followed bymiddle and inferior turbinates
Early signs are changes to the shape or color of existingmoles. The mole may itch, ulcerate or bleed.
Spread is by lymphatics and blood
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