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    CAUSES OF NASALMASS

    Joseph Lim071303503

    Group A1 Batch 22

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    Causes of Nasal Mass

    Congenital

    Dermoid cysts

    Glioma

    Encephalocele

    Acquired

    Neoplastic Non-neoplastic

    Benign Malignant

    Invertedpapilloma

    Juvenilenasopharyngeal

    angiofibroma Squamous

    papilloma Chondroma Haemangioma Rhinophyma

    Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma Olfactory

    neuroblastoma Hemangiopericytom

    a Plasmacytoma

    Nasal polyps Granulomas Traumatic Rhinolith

    Causes of Nasal Mass

    Congenital

    Dermoid cysts

    Glioma

    Encephalocele

    Acquired

    Neoplastic Non-neoplastic

    Benign Malignant

    Invertedpapilloma

    Juvenilenasopharyngeal

    angiofibroma Squamous

    papilloma Chondroma Haemangioma Rhinophyma

    Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma Olfactory

    neuroblastoma Hemangiopericytom

    a Plasmacytoma

    Nasal polyps Granulomas

    Rhinolith

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    Congenital

    Dermoid cysto Simple dermoid: Midline swelling under the skin in front of the

    nasal bone

    o Associated with sinus: Midline swelling on the dorsum of nose

    with an external opening (sinus). Hair may seen protruding

    through the sinus. Sinus track can go under nasal bone orintracranial dural - meningitis

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    Gliomaso Firm subcutaneous swelling on bridge, side of nose or near

    inner canthuso Nipped off portion of encephalocele during embryonic

    development

    o Occur in infants & children - 60% are extranasal

    o

    Firm, non compressible and size does not increase on crying,no transillumination and telangiectasis on skin

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    Extranasal Encephalocele/ Meningoencephaloceleo Subcutaneous pulsatile swelling in the midline at the root of the

    nose (nasofrontal), side of nose (nasoethmoid) or on theanteromedial aspect of orbit (naso-orbital)

    o Herniation of brain tissue & meninges through a congenital bony

    defect

    o Smooth, mobile, easily compressible, enlarges on crying, shows

    cough impulse and may be reducibleo Contains CSF and sometimes cerebral tissue

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    Causes of Nasal Mass

    Congenital

    Dermoid cysts

    Glioma

    Encephalocele

    Acquired

    Neoplastic Non-neoplastic

    Benign Malignant

    Invertedpapilloma

    Juvenilenasopharyngeal

    angiofibroma Squamous

    papilloma Chondroma Haemangioma Rhinophyma

    Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma Olfactory

    neuroblastoma Hemangiopericytom

    a Plasmacytoma

    Nasal polyps Granulomas

    Rhinolith

    Causes of Nasal Mass

    Congenital

    Dermoid cysts

    Glioma

    Encephalocele

    Acquired

    Neoplastic Non-neoplastic

    Benign Malignant

    Invertedpapilloma

    Juvenilenasopharyngeal

    angiofibroma Squamous

    papilloma Chondroma Haemangioma Rhinophyma

    Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma Olfactory

    neuroblastoma Hemangiopericytom

    a Plasmacytoma

    Nasal polyps Granulomas Traumatic Rhinolith

    Foreign

    bodies

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    Non-Neoplastic

    1. Nasal polyp

    o Non neoplastic masses of edematous, prolapsedmucosa of paranasal sinus/nasal cavity

    o Round, pedunculated, fleshy , grape-like mass which is

    greyish/bluish white translucent in colour with smooth

    glistening surfaceo Soft, mobile, insensitive, and does not bleed on touch

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    Aetiology

    o Chronic rhinosinusitis

    o Asthmao Aspirin intolerance

    o

    Cystic fibrosiso Allergic fungal sinusitis

    o Kartageners syndrome

    o Youngs syndrome

    o Churg-Strauss syndromeo Nasal mastocytosis

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    Pathology

    o End product of prolonged odemao Submucosa especially around middle meatus is lax

    and is easily water logged

    o

    Increase vascular permeability fluid retention(odema) prolapse of mucosa

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    Antrochoanal v/s Ethmoidal

    Pathology

    o Arises frommaxillary antrum

    o Usually unilateraland solitary

    o Arises fromethmoid sinuses

    o Bilateral due toallergy

    o Multiple due to

    multiple ethmoidair cells (8-20)

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    Antrochoanal v/s ethmoidal

    Clinical features- Symptomso Childreno Unilateral nasal

    obstruction Valvular

    o Bilateral if opposite

    choana is blocked in

    nasopharynx

    o Unilateral nasaldischarge-mucoid/mucopurulent

    o No allergy symptoms

    o Middle aged

    Exception: in cystic

    fibrosis/ mucovisidosisoccurs in children

    o Allergy symptoms+

    o Bilateral nasal

    obstruction/dischargeo Anosmia

    o Asthma/ aspirinintolerence

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    Antrochoanal v/s ethmoidalClinical features: Signs

    o Solitary and unilateralo Seen more postnasally

    than anteriorly

    o External: Frog-facedeformity +/-(intercanthal widening)

    o Multiple and bilateralo Seen more anteriorly

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    Tuberculosis

    Lupus vulgaris

    Sarcoidosis

    Leprosy

    Rhinoscleroma

    Foreign bodyoreosinophilicgranuloma

    Idiopathic

    Wegenersgranulomatosis

    Stewarts

    granuloma

    Fungal

    Rhinosporidiosis

    Spirochetal

    Syphilis

    Bacterial

    Granulomatous

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    Rhinoscleroma Caused by Klebsiella rhinoscleromatis

    (gram negative bacilli)

    Starts in the nose, extends tonasopharynx, oropharynx, larynx,

    trachea, and bronchi. 3 stages :

    Atrophic stage: foul smellingpurulent discharge

    Granulomatous stage: painless andnon-ulcerative nodules form in nasal

    mucosa, lips and external nose

    Hebra nose, woody feeling

    Cicatricial stage: Stenosis of nares,

    distortion of upper lip, adhesion in

    the nose, nasopharynx, and

    oropharynx.

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    Rhinosporidiosis

    Caused by yeast like fungi

    Rhinosporidium seeberi A leafy, polypoidal mass, pink

    to purple in colour, attached to

    nasal septum and lateral wall

    Surface is studded with whitedots sporangia of fungus

    Strawberry appearance

    Vascular and bleeds on touch

    May extend to nasopharynx

    and hang behind soft palate

    Nasal discharge blood

    tinged, epistaxis

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    3. Traumatic:

    Septal haematoma Collection of blood under the perichondrium or periosteum

    of the nasal septum Smooth soft rounded swelling of the septum in both the

    nasal fossae Bilateral nasal obstruction, frontal headache

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    Septal abscess

    Results from secondary infection of septal haematoma/

    follows furuncle of nose/upper lip Smooth bilateral swelling of the nasal septum

    Severe bilateral nasal obstruction Pain and tenderness over the bridge of nose.

    May associated with fever with chills, frontal headache Congested septal mucosa Enlarged submandibular lymph nodes

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    4. Rhinolith Stone formation in the nasal

    cavity Deposition of Ca and Mg salts

    around the nucleus of a small

    exogenous foreign body,

    blood clot or inspissatedsecretion.

    Pressure necrosis of

    septum/lateral wall.

    Unilateral nasal obstruction,foul smelling and blood-

    stained discharge.

    Grey /greenishmassirregular surfacestony hard

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    Foreign bodies

    If a child presents with unilateral, foul smelling nasaldischarge, foreign bodies must be excludedAetiology:

    pieces of paper, chalk, button, pebbles, seed

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    Causes of Nasal Mass

    Congenital

    Dermoid cysts

    Glioma

    Encephalocele

    Acquired

    Neoplastic Non-neoplastic

    Benign Malignant

    Invertedpapilloma

    Juvenilenasopharyngeal

    angiofibroma Squamous

    papilloma Chondroma Haemangioma Rhinophyma

    Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma

    Olfactoryneuroblastoma

    Hemangiopericytoma

    Plasmacytoma

    Nasal polyps Granulomas

    Rhinolith

    Causes of Nasal Mass

    Congenital

    Dermoid cysts

    Glioma

    Encephalocele

    Acquired

    Neoplastic Non-neoplastic

    Benign Malignant

    Invertedpapilloma

    Juvenilenasopharyngeal

    angiofibroma Squamous

    papilloma Chondroma Haemangioma Rhinophyma

    Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma

    Olfactoryneuroblastoma

    Hemangiopericytoma

    Plasmacytoma

    Nasal polyps Granulomas Traumatic

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    Benign Neoplastic

    Inverted papilloma

    Benign but locally aggressive premalignant tumor of thenasal cavity

    Pedunculated grey or reddish mass arise from the lateral

    nasal wall, usually in the region of the middle meatus and

    turbinate

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    Symptoms Elderly males, 4070 years old

    Unilateral nasal obstruction

    Blood stained nasal discharge

    Epistaxis

    Pain, epiphora, proptosis +/-

    H/O multiple previous nasal polypectomy+/-

    Signs Reddish, vascular, firm, mobile, insensitive

    pedunculated mass from lateral nasal wall

    Looks like unilateral infected polyp May bleed on probing

    Proptosis, facial swelling especially if associated with

    malignancy

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    Histologically benign yet locally

    aggressive tumour ofnasopharynx seen in adolescentboys

    Exact cause is unknown

    testosterone dependent? Site: posterior part of nasal cavity

    close to sphenopalatine foramen

    Made of vascular and fibrous

    tissue The vessels have a single endothelial cell lining without a

    muscle coat, which probably explains the tumor's

    propensity for hemorrhage; no muscle, cant contract.

    Juvenile Nasopharyngeal Angiofibroma (JNA)

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    Symptoms Adolescent males; 14-18 years

    Nasal obstruction, nasal discharge (80%)

    Profuse, painless, unprovoked paroxysms of epistaxis (60%) Less common symptoms include hearing loss, anosmia,

    mouth breathing, diplopia and blindness

    Signs Lobulated, firm, non-encapsulated mass, pink-gray or

    purple-red in colour, Sessile or pedunculated

    Probe test: CONTRAINDICATED

    Proptosis, palatal bulge, or swelling of the cheek or over the

    zygoma- Ominous indications of extensive tumor spread -tumor extension well beyond the nasopharynx.

    Otitis media

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    Intranasal meningoencephalocoele

    o Herniation of brain tissue and meninges through

    foramen caecum or cribriform plate

    o Present as smooth polyp in upper part of nose

    between septum and middle turbinateo Usually in infant and young children

    o Misdiagnosed as simple polyp excise

    meningealand brain damage

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    Squamous papilloma Similar to skin wart Can arise from nasal vestibule or

    lower part of nasal septum Maybe single /multiple,

    pedunculated/sessile

    Rhinophyma Slow-growing tumour, due to

    hypertrophy of the sebaceousglands of the tip of external nose

    Pink, lobulated mass over thenose with superficial vasculardilation.

    seen in the long standing case ofacne rosacea

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    Haemangioma

    Soft, dark red, pedunculated orsessile tumour

    Chondroma Arise from ethmoid, nasal cavity or

    nasal septum. Pure chondromas are smooth, firm

    and lobulated.

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    Causes of Nasal Mass

    Congenital

    Dermoid cysts

    Glioma

    Encephalocele

    Acquired

    Neoplastic Non-neoplastic

    Benign Malignant

    Invertedpapilloma

    Juvenilenasopharyngeal

    angiofibroma Squamous

    papilloma Chondroma Haemangioma Rhinophyma

    Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma

    Olfactoryneuroblastoma

    Hemangiopericytoma

    Plasmacytoma

    Nasal polyps Granulomas

    Rhinolith

    Causes of Nasal Mass

    Congenital

    Dermoid cysts

    Glioma

    Encephalocele

    Acquired

    Neoplastic Non-neoplastic

    Benign Malignant

    Invertedpapilloma

    Juvenilenasopharyngeal

    angiofibroma Squamous

    papilloma Chondroma Haemangioma Rhinophyma

    Ca of nasal cavity Malignant melanoma Lymphoma Sarcoma

    Olfactoryneuroblastoma

    Hemangiopericytoma

    Plasmacytoma

    Nasal polyps Granulomas Traumatic

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    Malignant neoplastic

    Carcinoma of nasal cavity

    Squamous cell carcinoma (80%) Vestibular Septal Lateral wall

    Adenocarcinoma and Adenoid cystic carcinoma

    Gland of mucous membrane or minor salivary glandsMalignant melanoma

    Malignant tumor of melanocytes, >50 years old Slate grey or bluish black polypoid mass

    Site usually at anterior part of nasal septum followed bymiddle and inferior turbinates

    Early signs are changes to the shape or color of existingmoles. The mole may itch, ulcerate or bleed.

    Spread is by lymphatics and blood

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