box jellyfish _ australian venom research unit

Upload: danielcc-lee

Post on 14-Apr-2018

217 views

Category:

Documents


0 download

TRANSCRIPT

  • 7/27/2019 Box Jellyfish _ Australian Venom Research Unit

    1/2

    ellyfish | Australian Venom Research Unit

    /www.avru.org/compendium/biogs/A000042b.htm[2010/6/15 09:13:45]

    Box jellyfish

    in category: Box jellyfish.

    The Box jellyfish (Chironex fleckeri) is found during the summer months in the

    coastal waters of northern Australia, from Gladstone in Queensland to Broome in

    Western Australia, but not on the Great Barrier Reef. It is the most dangerous

    jellyfish and indeed one of the most dangerous venomous creatures in the world.

    It is large, weighing up to 6 kg and measuring about 20-30 cm across the bell.

    The tentacles may stretch up to 2 metres. It is transparent in the water, and

    therefore difficult to see. It has 4 bundles of tentacles, which may number up to

    60 in total. Each tentacle contains many millions of nematocysts or stinging cells

    which discharge venom through the skin on contact. Contact with a large amount

    of tentacular material over a wide surface area can result in massive

    envenomation. Most stings occur in the summer months in shallow water near

    the beach, and are particularly common in children. (In two case series the

    average age of box jellyfish sting victims was 14 years with a median age of 11

    years.)

    Symptoms and Signs of Box Jellyfish Envenomation These can include:

    Severe localized pain, often associated with vigorous attempts by the patient

    to remove the tentacles (this may make the envenomation worse by causing

    the discharge of further nematocysts)

    Wide (0.5 -1cm) erythematous lines where the tentacles have been in

    contact with the skin. These may cover a large area, an indication of severe

    envenomation.

    Confusion, agitation, unconsciousness, collapse with respiratory failure

    and/or cardiac arrest

    cardiorespiratory arrest, or cardiac arrythmias

    difficulty with breathing, speech or swallowing

    severe pain

    extensive skin lesions.

    Avoid swimming in areas where box jellyfish are found during the jellyfish

    season (variable, but approximately September to March) and heed warning

    signs on beaches. N.B. avoid swimming alone or at remote beaches.

    Wear specially designed "stinger suits" while in known box jellyfish waters

    Swim at beaches patrolled by life savers, preferably equipped with vinegar,

    antivenom and basic resuscitation facilities

    Death can occur within 5 minutes following massive envenomation. The

    mechanism of toxicity are poorly understood, but death is thought to be due to

    respiratory failure, possibly central in origin, or to direct cardiotoxicity leading to

    A-V conduction disturbances or to paralysis of the cardiac muscle in systole.

    Patients may become unconscious before they can leave the water. There have

    been at least 63 confirmed deaths from envenomation by Chironex fleckeri in the

    Indo-Pacific region. In addition to cardiotoxic and neurotoxic properties, the

    venom also contains dermatonecrotic components producing patches of full

    thickness skin necrosis (see gallary images for 'Jellyfish') that may result in

    severe and permanent scarring. There is also a haemolytic component in

    Chironex fleckeri venom, although it is of doubtful clinical significance.

    Treatment of Box Jellyfish Envenomation Due to the rapidity of onset of

    symptoms, immediate first aid is vital and cardiopulmonary resuscitation may be

    required. Remaining undischarged nematocysts should be inactivated with large

    quantities of dilute (3-5%) acetic acid (i.e. household vinegar) once the patient

    has been safely removed from the water. Antivenom may be administered by

    lifesaving or other paramedical personnel at the scene, via the intramuscular

    route, although intravenous administration is preferable if appropriately skilled

    personnel are available. The antivenom, which has been available since 1970,

    consists of purified sheep immunoglobulin and no adverse reactions have been

    reported following its use in over 100 cases. Its efficacy has been established

    experimentally by in vitro neutralization and subsequent protection of

    experimental animals.

    Indications for Box Jellyfish Antivenom Box Jellyfish antivenom is recommended

    for all but minor stings. Specific indications include:

    In hospital, intravenous antivenom should be administered promptly if i t has not

    already been given or if the patient remains symptomatic. Assisted ventilation and

    narcotic analgesia may be required. Early administration of antivenom may result

    in reduced pain and decreased scarring secondary to dermatonecrosis.

    Precautions to Avoid Envenomation To minimise the risk of a potentially fatal box

    jellyfish sting in Australian beaches:

    http://www.avru.org/taxonomy/term/160http://www.avru.org/taxonomy/term/160
  • 7/27/2019 Box Jellyfish _ Australian Venom Research Unit

    2/2

    ellyfish | Australian Venom Research Unit

    /www.avru.org/compendium/biogs/A000042b.htm[2010/6/15 09:13:45]

    Exercise caution on entering the water (do not dive or run into the water)

    Strictly supervise children, who are more prone to stings, and whose lesser

    body weight may render them more susceptible to the effects of the venom

    Swim at beaches that have been netted to exclude box jellyfish

    Related

    Related

    Jellyfish

    Related

    Jellyfish, Australian

    http://www.avru.org/compendium/biogs/A000071b.htmhttp://www.avru.org/compendium/biogs/A000043b.htmhttp://www.avru.org/compendium/biogs/A000043b.htmhttp://www.avru.org/compendium/biogs/A000071b.htm