biennial report 2003-05

The OrganizationThe OrganizationThe OrganizationThe OrganizationThe Organization

Indian Institute of Chemical Technology (IICT ),Hyderabad, a national Laboratory and a constituentof Council of Scientific & Industrial Research (CSIR), isa premiere R&D Institute in India. Established in1944,the Institute has made significant contributionsin the field of Chemical Sciences & Technology. Majorareas of research are: Agrochemicals, Drugs &Pharmaceuticals, Organic Intermediates, Lipid Scienceand Technology, Organic Coatings & Polymers,Catalysis, Coal, Chemical Engineering and Design &Engineering , Chemical Biology and ChemicalInformatics

The VisionThe VisionThe VisionThe VisionThe Vision

To Become an innovative global R&D provider inthe field of chemical technology with referenceto industrial and speciality chemicals

To Be an institution of international excellence inbasic research in organic chemistry and alliedadjacent chemical and engineering sciences.

The MissionThe MissionThe MissionThe MissionThe Mission

To Provide globally competitive environmentallyfriendly technologies in agrochemicals,drugs,organic intermediates, fine chemicals, lipidsciences and technology, speciality polymers andallied chemicals.

To Achieve world class expertise in frontier areas inorganic synthesis, heterogeneous andhomogeneous catalysis and chemical process design,modelling and simulation.

To Build technical competence to offer science basedtechnical services world over in relevant areas ofchemical. biological and engineering sciences.

IICT endeavours to provide high quality analyticalendeavours to provide high quality analyticalendeavours to provide high quality analyticalendeavours to provide high quality analyticalendeavours to provide high quality analyticalservices which foster international standard basic andservices which foster international standard basic andservices which foster international standard basic andservices which foster international standard basic andservices which foster international standard basic andapplied research outputs in chemical, biological andapplied research outputs in chemical, biological andapplied research outputs in chemical, biological andapplied research outputs in chemical, biological andapplied research outputs in chemical, biological and

engineering sciences with a high degree of satisfaction andengineering sciences with a high degree of satisfaction andengineering sciences with a high degree of satisfaction andengineering sciences with a high degree of satisfaction andengineering sciences with a high degree of satisfaction andconfidence to the customers with continual improvement.confidence to the customers with continual improvement.confidence to the customers with continual improvement.confidence to the customers with continual improvement.confidence to the customers with continual improvement.

28-01-200428-01-200428-01-200428-01-200428-01-2004

ISO 9001: 2000 Accredited Laboratories

● Mass Spectrometry

● X-ray Crystallography

● Nuclear Magnetic Resonance

● Analytical Chemistry

● Scanning Electron Microscopy

● Organic Coatings and Polymers

● Coal/Gas Characterization

● Thermal Analysis

● Properties Evaluation

● Paper Testing

● Toxicology

● Pharmacology

CONTENTS

Page No.

ßÓu™N˛Á ........ I

FOREWORD ........ II

IICT’S R&D APPROACH AND OUTPUTS - OVERVIEW ........* R & D Approach ........ V

* Organisation Structure ........ VI

* Research and Management Councils ........ VII

* Human Resource Strengths ........ IX

* Applied Research Outputs ........ XI

* IPR Protection ........ XII

* Publications record ........ XIV

* Financial Performance ........ XV

* Performance Indicators per Scientist ........ XVII

“y∫N˛ \ÆÊoy Ã™Á∫Áz“ (ETÀo 5, 20035, 20035, 20035, 20035, 2003 Ãz ETÀo 4, 20044, 20044, 20044, 20044, 2004) ........ 3

DIAMOND JUBILEE CELEBRATIONS ........ 9

SECTORIAL R&D PERFORMANCE ........* CSIR Network Projects ........ 21

* Natural Products ........ 30

* Drugs & Pharmaceuticals ........ 33

* Agrochemicals & Pheromone Chemicals ........ 43

* Speciality & Fine Chemicals ........ 47

* Fluoroorganics ........ 48

* Inorganic & Physical Chemistry ........ 50

* Lipid Science & Technology ........ 55

* Organic Coatings & Polymers ........ 60

* Coal, Gas & Energy ........ 62

* Chemical & Instrument Analysis and NMR ........ 64

* Biology ........ 70

* Pharmacology ........ 73

* Chemical Engineering Sciences ........ 74

* Mechanical Design & Engineering ........ 81

* Computer Centre ........ 84

* Bioengineering and Environment Centre ........ 86

* General Engineering Services ........ 89

* Pilot Plant (Upscaling) Facilities ........ 90

* Business Management ........ 91

* Research Management ........ 95

* Information Management ........ 96

HUMAN RESOURCE DEVELOPMENT

* Training Programme ........ 99

* Symposia, Seminars, Workshop, etc. ........ 100

* Honours & Awards ........ 103

* Staff List ........ 105

* Distinguished Overseas Visitors ........ 112

ANNEXURES

* New Contracts Signed/Assignments Undertaken ........ 115

* Technologies / Processes Demonstrated ........ 128

* Technologies / Processes / Reports Released ........ 129

* Patents Filed ........ 135

* Patents Granted ........ 140

* Publications ........ 144

Compiled, Edited & Produced by : Business Management Division

Indian Institute of Chemical Technology

Hyderabad - 500 007

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uåtzΔN˛

FOREWORDThe Biennial Report period (2003-2005) is significant for the Indian Institute

of Chemical Technology in several ways. The Institute celebrated its Diamond

Jubilee during 2003-04 and in addition to the review of progress done by the lab

from Golden Jubilee to Diamond Jubilee period, the report also throws light on the

Institute’s mid performance of the 10th Five-Year Plan (2002-07) during 2003-04.

The Institute celebrated its Diamond Jubilee in a big way with special

programmes / seminars / workshops/ training courses/ lectures organized during

the reporting period and covered in a chapter separately in this report.

I took over as Director w.e.f. October, 2003 from Dr. K.V. Raghavan who served

as Director for 7 years w.e.f. January 11, 1996. I proposed a road map for the Institute

to achieve excellence in innovation and discovery driven research in healthcare,

industrial research, strategic materials, etc; our efforts are bearing fruit now and there is improvement in Institute’s

overall performance. The year 2004-05 has been an excellent year for us, since IICT stood first amongst CSIR labs in

Patents Filed (62), Patents Granted (56), Scientific Papers Published (408) and External Cash Flow (Rs. 18.5 crores). The

Institute initiated mega projects (2003-05) during the period and played major role as nodal laboratory for CSIR

Network Projects, (a) Developing Green Technologies for Organic Chemicals and (b) Globally Competitive Chemicals,

Processes and Products. A separate chapter gives details of the CSIR Network Projects.

In another major initiative, Government of AP sought IICT’s scientific expertise and design engineering

capabilities to set up a Biotechnology Incubation Centre (BTIC) at Genome Valley near Hyderabad. Department of

Biotechnology (DBT) is also supporting the project. Some of the other major projects undertaken and successfully

completed during the period are: TBBA (Solaris Chemicals), HFC-134a (SRF, Navin), Hafnium (NFC), DME (IOC),

Esfenvalerate (RPGLS), Degumming of rice bran oil (TMOP), Gas Cracker PP (GAIL). IICT also attracted major overseas

clients like Aisin Cosmos (Japan), Glaxo Smithkline (UK), Du Pont (USA), Givaudan (Switzerland) for custom synthesis

and other collaborative projects.

The Institute created the major facilities such as (a) Centre for Analysis of Chemical Toxins (CACT) with two

GC-MS and GC instrument (b) Pre-Biotechnology Incubation Centre (PBPC) and (c) High Resolution Mass Spectrometer.

In addition, a high pressure catalytic vapour phase reactor with data acquisition system and a high pressure batch

reactor system was procured. Also, GC-MS & Trackphere at the Pheromone Centre, Table Top X-ray Diffractometer

with auto sampler & Ion Chromatograph with a special feature of having on-line analysis were installed.

In brief, IICT’s performance during the reporting period has encouraged us to go for successful completion

of 10th Five-year Plan Programmes. I acknowledge and congratulate the Business Management Division to bring

out the report to the current shape in the shortest possible time and the excellent support provided by the Research

Management & Information Management Divisions and the concerned R&D and other Departments.

Hyderabad

March, 2006

(Dr. J.S. Yadav)

Director

VIVIVIVIVI

Research and Management Councils

Members:

Dr. K. NagarajanDirector (R&D)Recon Limited (R&D Centre)Bangalore

Prof. J.B. JoshiDirector, UDCT, Mumbai

Dr. (Mrs) Sheela Bhide, IASPrincipal SecretaryIndustries & CommerceGovt. of Andhra PradeshHyderabad

Dr. M.G. KulkarniDy.Director, NCL, Pune

Prof. S. ChandrasekaranIndian Institute of ScienceBangalore

Dr. S.K. AroraPresident (Drug Discovery)Lupin Laboratories LimitedMandideep, M.P.

Dr. A.K. BhatnagarDirector (R&D)Indian Oil Corporation LtdFaridabad – 121 001.

Dr. G.N. QaziDirector, RRL, Jammu

Dr. K V RaghavanDirector, IICT

Permanent InviteeDG or his nominee

SecretaryShri T. SuryanarayanaTechnical Officer E II, IICT

RESEARCH COUNCIL OF IICT (2001-03) RESEARCH COUNCIL OF IICT (2003-05)

Members:

Prof. Ashutosh SharmaIndian Institute of TechnologyKanpur – 208 016

Prof. Mihir Kanti ChaudhuriIndian Institute of TechnologyGuwahati – 781039

Prof. Javed IqbalDistinguished Research ScientistDr. Reddy’s Laboratories LtdHyderabad – 500 050

Dr. Sumit BhaduriHead of ResearchM/s Reliance Industries LtdMumbai – 400 072

Prof. D.BalasubramanianDirector of ResearchL.V.Prasad Eye InstituteHyderabad – 500 034

Dr. P.K.GhoshDirector, Central Salt & MarineChemical Research InstituteBhavnagar – 364 002

SecretaryDeptt. of Chemicals andPetrochemicals, Govt. of IndiaNew Delhi – 110 001

Dr. M.K. GurjarScientist-GNCL, Pune – 411 008

Dr. J.S.YadavDirector, IICT


SecretaryDr.M.Vairamani, Scientist G, IICT

ChairmanProf. R.Kumar

Jawaharlal Nehru Centrefor Advanced Scientific Research

Bangalore – 560 012

ChairmanProf. R. Kumar

Jawaharlal Nehru Centrefor Advanced Scientific Research

Bangalore – 560 012

VIIVIIVIIVIIVII

Members

Dr.M.Vairamani,Scientist “F”IICT - Hyderabad

Dr. G.V.M.SharmaScientist “EII”IICT - Hyderabad

Dr. B. SatyavathiScientist “B”IICT - Hyderabad

Dr. D.Vijay KumarScientist “C”IICT - Hyderabad

Dr. B.V.S.K.RaoTechnical Officer “B”IICT - Hyderabad

Members

Shri G.Sampath KumarScientist “F”IICT, Hyderabad

Dr. P.Shantan RaoScientist “EII”IICT, Hyderabad

Mrs. C.B.LakshmiScientist “EII”IICT, Hyderabad

Dr. (Mrs.) A.L.PrasunaScientist “EI”IICT, Hyderabad

Dr. N. NarenderScientist “B”IICT, Hyderabad

MANAGEMENT COUNCIL OF IICT(1-7-2001 to 30-06-2003)

MANAGEMENT COUNCIL OF IICT(1-7-2003 to 30-6-2005)

ChairmanDr. K.V. Raghavan

DirectorIICT, Hyderabad

ChairmanDr. J.S.Yadav

DirectorIICT, Hyderabad

Dr. Veena K Parnaik,Sci.”F”,CCMB, Hyderabad

Shri T.Krishna ReddySci.”G”,IICT - Hyderabad

Sr.F&AO(SG)/Sr.F&AO/F&AOIICT - Hyderabad


Member SecretaryIICT - Hyderabad

Shri Uday RangrezTech. Officer “E”IICT, Hyderabad

Sr. FAO/FAOIICT, Hyderabad


COAMember-SecretaryIICT, Hyderabad

Research Council Meeting in progress

VIIIVIIIVIIIVIIIVIII

Human Resource Strengths

IXIXIXIXIX

Human Resource Strengths

XXXXX

Applied Research Outputs

XIXIXIXIXI

IPR’s Protection

XIIXIIXIIXIIXII

IPR’s Protection

XIIIXIIIXIIIXIIIXIII

Publications Record

XIVXIVXIVXIVXIV

XVXVXVXVXV

Financial Performance

Financial Performance

XVIXVIXVIXVIXVI

XVIIXVIIXVIIXVIIXVII

Performance Indicators Per Scientist

Performance Indicators Per Scientist

XVIIIXVIIIXVIIIXVIIIXVIII

Diamond Jubilee Celebrations

(August 5, 2003 to August 4, 2004)

“y∫N˛ \ÆÊoy Ã™Á∫Áz“ETÀo 5, 2003 - ETÀo 4, 2004

3

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1. “y∫N˛ \ÆÊoy Ã™Á∫Áz“Áı N˛Á ΔÏßÁ∫Êß - 5 ETÀo, 2003

“y∫N˛ \ÆÊoy (1944-2004) Ã™Á∫Áz“Áı N˛Á ΔÏßÁ∫Êßut. 5 ETÀo, 2003 N˛Áz “y∫N˛ \ÆÊoy À™wuo uY“Ωå NzEåÁƒ∫m Ãz “ÏEÁ@ gÁ}. ™ÁÃÁ™y FåÁtÁ, EÜÆq, ™zÃÃ|LuÃå N˛ÁÃ™Á}Ã, \ÁúÁå ™ÏPÆÁuous ∫“z@ EÁF| EÁF| Ãy byåz ™zÃÃ| LuÃå N˛ÁÃ™Á}Ã (\ÁúÁå), Nz Ãy úy (“{t∫Á§Át)osÁ Nz .Lå.§ÆÁzbzN˛ (“{t∫Á§Át) Nz ÃÁs FÃ EƒÃ∫ ú∫N˛∫Á∫åÁ™Áı ú∫ “ÀoÁq∫ uN˛Æz@ ÃÊÜÆÁ Ã™Æ Nz ÃÁÊÀNw uoN˛N˛ÁÆ|N¿ ™ Ãz Ã™Á∫Áz“ ÃÊúëÁ “ÏEÁ@

2. <YÁƒ¬ ßÓÃy oz¬ ÃÊÃÁáå ™ı EÁáÏuåN˛ EåÏÃÊáÁå ƒuƒN˛ÁÃ EÁÆÁ™ osÁ Gú-GnúÁtå GúÆÁzT> ú∫ ∫Á…b~yÆÃ©™z¬å - 30 ETÀo, 2003

u¬uúg uƒrÁå ƒ üÁ{ ÁzuTN˛y üßÁT åz ‘ßÁ∫oyÆ oz¬üÁ{ ÁzuTN˛y ÃÊV’(OTAI) (tuqm ™Êg¬) Nz ÃÁs ‘YÁƒ¬

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3. EÜÆÁúN˛ utƒÃ Ã™Á∫Áz“ - 5 uÃo©§∫, 2003

ÃÊÀsÁå åz EÁÊá¿ ützΔ uƒrÁå EN˛Át™y Nz ÃÁs 5uÃo©§∫, 2003 N˛Áz EÁF| EÁF| Ãy by “y∫N˛ \ÆÊoy EÜÆÁúN˛utƒÃ Ã™Á∫Áz“ N˛Á ÃÊÆÏMo EÁÆÁz\å uN˛ÆÁ@ GMo EƒÃ∫ú∫ üÁz.Lå.ÃnÆ™Óuo|, gyå ¢z N˛¡by ™Á™¬z, EÁF| EÁF| by,N˛ÁåúÏ∫ Á∫Á LN˛ uƒΔz EußßÁ m utÆÁ TÆÁ@ üÁz.úy.Nz .ÃÁF|üN˛ÁΔ, ™ÁååyÆ ÃuYƒ, EÁÂ.ü. uƒrÁå EN˛Át™y osÁ gÁ}.∫oå L¢˛. bÓuN| , §“Ï¬N˛ ∫ÃÁÆår, F| L™ EÁ∫ Ãy, Ãy¢z¬,“{t∫Á§Át Á∫Á ZÁfiÁı Nz u¬L GúÆÁzTy ƒ{rÁuåN˛ Ãfi EÁÆÁzu\ouN˛Æz TÆz@

“y∫N˛ \ÆÊoy Ã™Á∫Áz“ (ETÀo 5, 20035, 20035, 20035, 20035, 2003 Ãz ETÀo 4, 20044, 20044, 20044, 20044, 2004)

4

4. u“ãty ™ı ∫Á…b~yÆ ÃÊTÁz…ey -15 uÃo©§∫, 2003

‘∫ÃÁÆå ƒ \yƒ uƒrÁå ™ı EÊo∫ u§ÊtÏ - å√Æ uƒN˛ÁÃ’ u“ãty™ı LN˛ ∫Á…b~yÆ ÃÊTÁz…ey N˛Á EÁÆÁz\å ut. 15.9.2003 N˛ÁzuN˛ÆÁ TÆÁ@ üÁz.Ãy.ÃÏ£§Á∫Áƒ, EÜÆq, EÁÂ.ü., ∫Á[Æ GÄÁuΔqÁ úu∫ tΩ FÃ Ã™Á∫Áz“ Nz ™ÏPÆ Euous ∫“z@ ÃÊTÁz…ey N˛ÁüÁ∫Êß üΔÁÃå uåÆÊfiN˛ »y. ∫ÁNz Δ NÏ ™Á∫ Δ™Á| Nz ÀƒÁToƒYå Ãz “ÏEÁ@ ™ÏPÆ Euous åz Eúåz ßÁ m ™ı u“ãty NzÃÁs-ÃÁs üÁÊoyÆ ßÁ ÁEÁzÊ Nz uƒN˛ÁÃ ú∫ \Áz∫ utÆÁ EÁ{∫u“ãty ™ı EuáN˛ÁuáN˛ N˛Á™ N˛∫åz Nz u¬L ƒ{rÁuåN˛Áı N˛ÁEÁ“ΩƒÁå uN˛ÆÁ@ gÁ}. üN˛ÁΔ ƒy. utƒÁå åz ÃÊTÁz…ey Nz ƒ{rÁuåN˛-Ãfi N˛Á ÃÊYÁ¬å uN˛ÆÁ@

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gÁ}.gy.Δ{¬\Á, ƒ{rÁuåN˛, EÁF|.EÁF|.Ãy.by.åz ‘™ÂÓT¢˛¬yßÊgÁ∫m ™ı N˛yb ü§ãá “zoÏ uåÆÊufio uƒ™ÏuMo Nz u¬L §“Ï¬N˛ÃÁáå-, LN˛ EÁáÏuåN˛ ú“¬Ó’ EÁ{∫ gÁ}. EëÁúÓmÁ| \zbΩby,ƒ{rÁuåN˛, EÁF|.EÁF|.Ãy.by. åz ‘‘N˛ÁzuΔN˛Á - uƒΔÏÚ ∫ÃÁÆåN˛Á∫QÁåÁ” uƒ ÆÁı ú∫ ƒ{rÁuåN˛ ¬zQ üÀoÏo uN˛Æz@ gÁ}.ƒy.Nz .∫Áƒ, ƒ{rÁuåN˛ Lå.\y.EÁ∫.EÁF|., gÁ}.ƒy.Nz . ÀMÃzåÁ,ƒ{rÁuåN˛ Lå.\y.EÁ∫.EÁF|.EÁ{∫ gÁ} G Á TÁzÀƒÁ™y, ƒ{rÁuåN˛,Lå. EÁF|. EÁz, TÁzƒÁ EÁut åz ßy ƒ{rÁuåN˛ - ¬zQ üÀoÏouN˛Æz@ ƒ{rÁuåN˛Áı åz Eúåz ¬zQÁı ˚Á∫Á ∫ÃÁÆå LƒÊ \yƒuƒrÁå Nz EÊo∫ u§ãtÏEÁzÊ ú∫ YYÁ| N˛y EÁ{∫ u“ãty Nz ™ÁÜÆ™Ãz ∫ÃÁÆå LƒÊ \yƒ uƒrÁå N˛y uM¬…b §Áoı §‰gz Ã“\ ‰jÊTÃz »ÁzoÁEÁzÊ Nz ÃÁ™åz ∫Qåz N˛y N˛ÁzuΔΔ N˛y@

EÊo ™ı ÃÁÊÀNw uoN˛ N˛ÁÆ|N¿ ™ ™ı ‘§y™Á∫ N˛Á{å?’ åÁ™N˛“ÁÀÆ åÁbN˛ N˛Á ™ÊYå uN˛ÆÁ TÆÁ@

5. ‘\‰gy §Óby uYuN˛nÃÁ N˛Á ƒ{u≈ƒN˛ úu∫tw≈Æ’ ú∫EÊo∫Á|…b~yÆ Ã©™z¬å - 19 uÃo©§∫-20 uÃo©§∫, 2003

EÁF| EÁF| Ãy by, EÁF| \y Lå L osÁ ™{MÃ ™Ï¬∫ ßƒå,YzëÁF| ˚Á∫Á ÃÊÆÏMo øú Ãz EÁÆÁzu\o Æ“ Ã©™z¬å 19-20uÃo©§∫, 2003 N˛Áz EÁF| EÁF| Ãy by ™ı “ÏEÁ@ EÁ{ á qzfi NzEåÏÃÊáÁå - N˛o|Á, EN˛Át™y ÃtÀÆ, uYuN˛nÃN˛, uƒ˘Áus|ÆÁı ƒ

G˘ÁzTúuoÆÁı åz FÃ Ã©™z¬å ™ı ßÁT u¬ÆÁ@ gÁ}.Ãy.Nz . N˛ÁzN˛Ábz,Gú N Ï¬úuo, N˛ÁN˛oyÆ uƒ≈ƒuƒ˘Á¬Æ åz Ã©™z¬å N˛Á GtΩáÁbåuN˛ÆÁ@ Eúåz GtΩVÁbå ßÁ m ™ı üÁz. N˛ÁzN˛Ábz åz Ã™Á\ Nz u“oNz u¬L \‰gy §Óby-EÁáÁu∫o EÁ{ áÁı Nz uƒN˛ÁÃ N˛y EÁƒ≈ÆN˛oÁú∫ \Áz∫ tzoz “ÏL N˛“Á uN˛ Fã“Î Nz N˛Á∫m üÁYyå ßÁ∫o uƒ≈ƒN˛Á ET¿tÓo §åÁ “ÏEÁ sÁ@ gÁ}. (»y™oy) F| ∫Áu“™y, uåtzΔN˛,L™ L™ §y åz GtΩVÁbå Ã™Á∫Áz“ N˛y EÜÆqoÁ N˛y@ \‰gy §ÓbyEÁ{ á uƒN˛ÁÃ Nz EåzN˛ qzfiÁı ™ı N˛ÁÆ|∫o uƒuΔ…b ƒMoÁEÁzÊ åz\‰gy §Óby EÁ{ á uƒN˛ÁÃ Nz Fuo“ÁÃ Ãz EÁ∫Êß N˛∫ \‰gy §ÓbyEÁ{ á ™ÁåN˛yN˛∫m, \‰gy §Óby ãÆÓb~ÁÃÓubN˛¡Ã N˛Á uƒN˛ÁÃ, \‰gy§Óby EÁ{ áÁı N˛y ÃÏ∫qÁ Ãz ¬zN˛∫ üNw uoN˛ GnúÁtÁı ™ı ÃÊßÁƒåÁEÁzÊoN˛, EåzN˛ uƒ ÆÁı ú∫ Eúåz EåÏßƒÁı N˛Á EÁtÁå ütÁå uN˛ÆÁ@gÁ}.\z.L™.∫Áƒ, Gú uåtzΔN˛, üÁNw uoN˛ GnúÁt üßÁT åz \‰gy§Óby EÁ{ áÁı Nz ƒ{rÁuåN˛ uƒN˛ÁÃ “zoÏ ƒ{rÁuåN˛ úÚuoÆÁı NzGúÆÁzT ú∫ ßÁ m utÆÁ@ Ã©™z¬å ™ı otÏú∫ÁÊo “ÏF| ú{åz¬úu∫YYÁ| ™ı Ã©™z¬å Nz úÁeΩÆN¿ ™ Nz tÁ{∫Áå GeÁÆz TÆz ™ÏPÆ™ÏtΩtÁı ú∫ uƒYÁ∫ uƒ™Δ| uN˛ÆÁ TÆÁ@ FÃ ú{å¬ Nz uƒΔz rÁı ™ıgÁ}. ÃÊ\yƒ ∫Áƒ, ßÓoúÓƒ| EÁ{ á uåÆÊfiN˛ EÜÆq, gÁ}.Nz .ƒy.∫ÁVƒå, uåtzΔN˛, EÁF| EÁF| Ãy by, üÁz. “zYúyby E©™Ázå,ÃzƒÁ™ÏMo üÁz¢z Ã∫, gÁ}.\z. L™.∫Áƒ. EÜÆq, üÁNw uoN˛ GnúÁtüßÁT, EÁF| EÁF| Ãy by EÁut ΔÁu™¬ “ÏL@ Æ“ Ãƒ|Ã©™uo Ãzuåm|Æ u¬ÆÁ TÆÁ uN˛ uYuN˛nÃÁ úÁ{áÁı Nz uYuN˛nÃyÆ øú ÃzÃuN¿ Æ ßÁT N˛Áz Ã™^åz N˛y utΔÁ ™ı N˛ÁÆ| N˛∫åÁ EnÆuáN˛EÁƒ≈ÆN˛ “{@ tÁΔ|uåN˛ onƒÁı N˛y Eƒ“z¬åÁ å N˛∫oz “ÏL uƒußëÁÀo∫Áı ú∫ uƒ≈¬z mÁn™N˛ ™ÁåN˛Áı N˛y ÀsÁúåÁ N˛∫åz ú∫ EuáN˛\Áz∫ utÆÁ TÆÁ@ FÃ Ã©™z¬å Nz Ã“-ÃÊÆÁz\N˛ gÁ}.\z.LÃ.ÆÁtƒ,»y.Nz .ƒy.EÁ∫.LÃ.™Óuo| EÁ{∫ gÁ}. üN˛ÁΔ ƒy. utƒÁå ∫“z@

6. EÁF| EÁF| Ãy by “y∫N˛ \ÆÊoy »wÊQ¬Á - 21 uÃo©§∫,2003

gÁ}.EÁ∫.L.™ÁΔz¬N˛∫, ™“ÁuåtzΔN˛, Ãy LÃ EÁF| EÁ∫ ƒÃuYƒ, gy LÃ EÁF| EÁ∫ (ßÁ∫o Ã∫N˛Á∫) åz 21 uÃo©§∫,2003 N˛Áz EÁF| EÁF| Ãy by ™ı ‘EÁF| EÁF| Ãy by “y∫N˛\ÆÊoy »wÊQ¬Á’ N˛Á GtΩVÁbå uN˛ÆÁ@ üÁz. EÁ∫. NÏ™Á∫ EÜÆq,EÁF| EÁF| Ãy by EåÏÃÊáÁå úu∫ tΩ åz Ã™Á∫Áz“ N˛y EÜÆqoÁN˛y@ uå©å N˛ÁÆ|N¿ ™ Ã©úëÁ “ÏL:

úÏåøÚÁu∫o ™ÏPÆ ßƒå ™ı åF| EåÏÃÊáÁå üÆÁzTΔÁ¬ÁEÁzÊN˛Á GtΩVÁbå∫ÁÃÁÆuåN˛ tÏV|båÁ uåÆÊfim Nı ¸ N˛Á GtΩVÁbå

Biennial Report 2003-2005

5

EÁF| EÁF| Ãy by úu∫Ã∫ N˛Á úÏå: ƒåÁ∫Ázúm osÁ“u∫oyN˛∫m N˛Á GtΩVÁbå‘LåuƒÃ’ Nı ¸ N˛Á GtΩVÁbåEÁF| EÁF| Ãy by ™Áåƒ ÃÊÃÁáå uƒN˛ÁÃ ü¬zQ N˛Áuƒ™ÁzYåEÁF| EÁF| Ãy by N˛™|YÁu∫ÆÁı ƒ ΔÁzá ZÁfiÁı N˛Áz “y∫N˛\ÆÊoy À™wuo uY“ΩåÁı N˛Á uƒo∫mEÁÊá¿ ützΔ Nz ™“Á gÁN˛úÁ¬, »y.by.LÃ. TÁzuƒÊt∫Á\å˚Á∫Á “y∫N˛ \ÆÊoy À™Á∫N˛ uƒΔz gÁN˛ u¬¢˛Á¢z N˛Áuƒ™ÁzYå@gÁ}.EÁ∫.L. ™ÁΔz¬N˛∫ Á∫Á “y∫N˛ \ÆÊoy EußßÁ m@gÁ}.Nz .ƒy. ∫ÁVƒå N˛y üÀoÏuo: Z: tΔN˛Áı ™ı EÁF| EÁF|Ãy by N˛Á N¿ ™ uƒN˛ÁÃ@ƒ{rÁuåN˛ ¬zQ üÀoÏoyN˛∫m

7 Ãy.LÃ.EÁF|.EÁ∫. ÀsÁúåÁ utƒÃ - 26 uÃo©§∫, 2003

ut. 26 uÃo©§∫ 2003 N˛Áz ÃÊÀsÁå åz ƒ{rÁuåN˛ LƒÊEÁ{ ÁzuTN˛ EåÏÃÊáÁå úu∫ tΩ ÀsÁúåÁ utƒÃ ™åÁÆÁ@ FÃEƒÃ∫ ú∫ üÁz. ƒÁF| ƒıN˛b∫Á™ ∫zgΩgy, GúNÏ¬úuo, \ƒÁ“∫¬Á¬åz“ø uƒ≈ƒuƒ˘Á¬Æ, “{t∫Á§Át Ã©™ÁååyÆ Euous ∫“z@Ã™Á∫Áz“ N˛y ü™ÏQ §Áoı uå©åÁåÏÃÁ∫ “¯:-

ÃÊÀsÁå uåtzΔN˛ ˚Á∫Á EÜÆqyÆ ßÁ m\{ƒüÁ{ ÁzuTN˛y H…™ÁÆå EußN˛¡úåÁEÁzÊ N˛Á EåÁƒ∫m25 ƒ | N˛y ÃzƒÁ Ã™Áuõo ú∫ N˛™|YÁu∫ÆÁı N˛Áz À™wuouY“Ωå ütÁå N˛∫åÁÃzƒÁ uåƒwno N˛™|YÁu∫ÆÁı N˛Á Ã©™ÁåN˛uå…e / ƒu∫…e ΔÁzá ZÁfiÁı N˛Áz EåÏÃÊáÁå ¬zQ üN˛ÁΔåú∫ úÏ∫ÀN˛Á∫\z EÁ∫ L¢˛ Nz u¬L gÁ}. EÁ∫. Lå. Δ™Á| À™Á∫N˛úÏ∫ÀN˛Á∫, LÃ EÁ∫L¢˛ Nz u¬L »y TÁzúÁ¬Nw …m ∫ÁƒƒzúYztÏ À™Á∫N˛ úÏ∫ÀN˛Á∫u§bΩÃ, uú¬Áåy Nz L™ LÃ ∫ÁÃÁÆuåN˛ üÁ{ Á{uTN˛yuƒ˘Áus|ÆÁı Nz u¬L ü™Ámúfi LƒÊ N˛™|YÁu∫ÆÁı Nz §ÄÁÁı,u\ã“Áıåz ßÁ∫oyÆ üÁ{ Á{uTN˛yÆ ÃÊÀsÁå (IIT) ™ı üƒzΔüÁõo uN˛ÆÁ, Nz u¬L ZÁfiƒwuÆÁı N˛y VÁz mÁN˛™|YÁu∫ÆÁı Nz §ÄÁÁı, u\ã“Áıåz §Á∫“ƒÎ N˛y ú∫yqÁ ™ı

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EÁF| EÁF| Ãy by “y∫N˛ \ÆÊoy Qz¬ úÏ∫ÀN˛Á∫ Ã™Á∫Áz“N˛Á EÁÆÁz\å ßy FÃ EƒÃ∫ ú∫ uN˛ÆÁ TÆÁ@ »y. E∫ΔtEÆÓ§, ßÁ∫oyÆ uN¿ Nz b by™ Nz ßÓoúÓƒ| ÃtÀÆ, FÃ N˛ÁÆ|N¿ ™Nz ™ÏPÆ Euous ∫“z@ ™ÏPÆ Euous åz ÃÊÀsÁå Nz Gno™uQ¬ÁugÆÁı N˛Áz úÏ∫ÀN˛Á∫ ütÁå uN˛ÆÁ@

8. Nz .by. EÄÁÆΩÆÁ À™Á∫N˛ ßÁ m - 6 EMoÓ§∫, 2003

oz¬ ƒ ƒÃÁ Nz qzfi ™ı EåÏÃÊáÁå ƒ uƒN˛ÁÃ Nz u¬L gÁ}.EÄÁÆΩÆÁ Nz ÆÁzTtÁå N˛Áz tzQoz “ÏL Gã“ı »ÈÊÁ\¬y tzåz NzGtΩtz≈Æ Ãz GåNz \ã™utå ú∫ ßÁ∫oyÆ oz¬uΔ¡ú ƒ{rÁuåN˛ÃÊV åz üuo ƒ | À™Á∫N˛ ßÁ m EÁÆÁzu\o N˛∫åz N˛Á uåm|Æu¬ÆÁ “{@ EÁF|.EÁF|.Ãy.by. üzqÁTw“ ™zÊ 6 EMoÓ§∫, 2003 N˛ÁzgÁ}.Nz .by. EÄÁÆΩÆÁ Nz Vuå…e Ã“ÆÁzTy gÁ}. úy. L™. ßÁT|ƒ,ßÓoúÓƒ| uåtzΔN˛ Ãy.Ãy.L™.§y. åz gÁ} Nz .by. EÄÁÆΩÆÁ À™Á∫N˛ßÁ m utÆÁ@ gÁ}.\z.LÃ.ÆÁtƒ åz üuoßÁuTÆÁı N˛Á ÀƒÁTouN˛ÆÁ EÁ{∫ »ÁzoÁTm N˛Áz ƒMoÁ N˛Á úu∫YÆ utÆÁ@ gÁ}.Nz .by.EÄÁÆΩÆÁ Nz \yƒå ƒwno Ãz »ÁzoÁTm N˛Á úu∫YÆ N˛∫ÁÆÁTÆÁ@

gÁ}. N˛ÁıTgÁ Y©™Ï EÄÁÆΩÆÁ N˛Á \ã™ 6 EMoÓ§∫, 1923N˛Áz ou™¬åÁgÓ Nz N˛Ázu¡¬uT¬ TÁ}ƒ ™ı “ÏEÁ sÁ@ Δ{qumN˛¬flÆ üÁuõo Nz ú≈YÁoΩ ƒ | 1950 ™ı Gã“Áıåz üÆÁzTΔÁ¬Á ™ıN˛ÁÆ|ßÁ∫ ÃÊßÁ¬Á osÁ ƒ | 1971 oN˛ ÃÊÀsÁå Ãz \Ï‰gz ∫“z@Gú uåtzΔN˛ osÁ oz¬ ƒ ƒÃÁ üßÁT Nz EÜÆq Nz øú ™ıGã“Áıåz u¬uúg ∫ÃÁÆåΔÁÀfi ƒ üÁ{ ÁzuTN˛y ™ı ƒ{rÁuåN˛Áı N˛ÁzN˛Á™ N˛∫åz N˛Áz üÁznÃÁu“o uN˛ÆÁ EÁ{∫ FÃz åF| utΔÁ ty@ gÁ}.EÄÁÆΩÆÁ N˛Áz EåzN˛ ∫Á…b~yÆ ƒ EÊo∫Á|…b~yÆ úÏ∫ÀN˛Á∫Áı ÃzÃ©™Áuåo uN˛ÆÁ TÆÁ@ 5 uÃo©§∫, 2002 N˛Áz gÁ} EÄÁÆΩÆÁ N˛Áuåáå “ÏEÁ@ ßÁ∫oyÆ ∫ÁÃÁÆuåN˛ üÁ{ ÁuTN˛y ÃÊÀsÁå Nz™ÏPÆ ßƒå N˛Á úÏåøÚÁu∫o tÓÃ∫Á o¬ gÁ}.Nz .by. EÄÁÆΩÆÁuƒÊT Nz øú ™ı åÁu™o uN˛ÆÁ TÆÁ, u\ÃN˛Á úˆßÓ mgÁ}.úy.L™.ßÁT|ƒ, ÃÊÀsÁúN˛ uåtzΔN˛, Ãy Ãy L™ §y åzGtΩVÁbå uN˛ÆÁ@

9. ßÁ∫oyÆ ∫ÁÃÁÆuåN˛ üÁ{ ÁzuTN˛y ÃÊÀsÁå ÀsÁúåÁ utƒÃEußßÁ m - 7 åƒ©§∫, 2003

<Lå.L™.EÁ∫. GúÆÁzT Nz åƒyå EÁÆÁ™: ∫ÁzT uåtÁå,uYuN˛nÃÁ uåÆÊfim osÁ ünÆq ÃÁ™Áu\N˛ Ã©§ãá>, uƒ Æ

“y∫N˛ \ÆÊoy Ã™Á∫Áz“ (ETÀo 5, 2003 Ãz ETÀo 4, 2004)

6

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10 úÆÁ|ƒ∫myÆ ∫ÃÁÆåΔÁÀfi ú∫ ÆÓåzÀN˛Áz qzfiyÆ üuΔqmN˛ÁÆ|ΔÁ¬Á - 10-15 åƒ©§∫, 2003

Æ“ N˛ÁÆ|ΔÁ¬Á 10 åƒ©§∫ Ãz 15 åƒ©§∫, 2003 oN˛“ÏF|@ ÆÏåzÀN˛Áz qzfiyÆ Nı ¸, ut®y Á∫Á üÁÆÁzu\o úÆÁ|ƒ∫myÆ∫ÃÁÆåΔÁÀfi ú∫ Æ“ EÁƒÁÃyÆ N˛ÁÆ|ΔÁ¬Á-Ã“-üuΔqmúÁeΩÆN¿ ™ ßÁ∫o osÁ GÃNz ú‰gÁzÃy tzΔÁı \{Ãz »y¬ÊN˛Á,§ÊT¬ÁtzΔ osÁ åzúÁ¬ N˛y uΔqm ¢{ N˛¡by Nz u¬L EÁÆÁzu\ouN˛ÆÁ TÆÁ@ ßÁ∫o Ãz 12 osÁ »y¬ÊN˛Á Ãz 4, §ÊT¬ÁtzΔ Ãz1 osÁ åzúÁ¬ Ãz 1 üuoßÁTy, NÏ ¬ 18 üuoßÁuTÆÁı åz FÃN˛ÁÆ|ΔÁ¬Á ™ı ßÁT u¬ÆÁ@

15 åƒ©§∫, 2003 N˛Á z Ã™Áúå Ã™Á∫Áz“ ™ıgÁ}.\z.LÃ.ÆÁtƒ, uåtzΔN˛, EÁF|.EÁF|.Ãy.by., åz üuoßÁuTÆÁıN˛Áz ü™Ám úfi üÀoÏo uN˛Æz@ gÁ}.L™.LÃ.EÁ¬™, ƒu∫…e N˛ÁÆ|N¿™uƒΔz r ƒ{rÁuåN˛, ÆÏåzÀN˛Áz, åF| ut®y FÃ Ã™Á∫Áz“ Nz™ÏPÆÁuous ∫“z@ gÁ}.L™.ƒ{∫™um, Gú uåtzΔN˛ ƒ EÜÆq,uƒ≈¬z mÁn™N˛ ∫ÃÁÆå ΔÁÀfi üßÁT åz úÁeΩÆN¿™ N˛Á ÃÊuqõoøú üÀoÏo uN˛ÆÁ@

11 úÁ∫Êúu∫N˛ F|áå Ãz F|áå §{b∫y - ∫Á…b~yÆ Ã©™z¬å - 4-5 utÃ©§∫, 2003

4-5 utÃÊ§∫, 2003 N˛Áz EÁÆÁzu\o Ãzu™åÁ∫, T{∫-úÁ∫©úu∫N˛ H\Á| ÕÁÁzo ™ÊfiÁ¬Æ ˚Á∫Á Ã“-üÁÆÁzu\o uN˛ÆÁTÆÁ@ gÁ}.Nz .§y.LÃ.üÃÁt, EÜÆq, N˛ÁzÆ¬Á, T{Ã ƒ H\Á|üßÁT, EÁF|.EÁF|.Ãy.by., “{t∫Á§Át åz Ã©™z¬å N˛y ™“noÁN˛Á ÃÊuqõo úu∫YÆ utÆÁ@ EÁ\Nz úu∫tw≈Æ ™ı, N˛Á§|å GnÃ\|åNz §‰joz Ào∫ Nz üuo ƒ‰joy “ÏF| \ÁåN˛Á∫y Nz N˛Á∫m F|áå§{b∫y üÁ{ ÁzuTN˛y åz Ãßy GúÆÁzT “zoÏ úÁ∫©úu∫N˛ H\Á|GnúÁtå Nz Lƒ\ Nz øú ™ı ƒ{u≈ƒN˛ øú Ãz ™“Áå ÃÊTuo§åÁL ∫Qy “{@ ƒ{rÁuåN˛Áı EÁ{∫ GnúÁtN˛Áı Nz Ã™q YÏåÁ{oyÆ“ “{ uN˛ LzÃy F|áå üN¿™ ümÁ¬y N˛Áz üÁõo uN˛ÆÁ \ÁÆ, \ÁzÃÁ™ÁãÆ Ào∫ N˛y ÀƒXZoÁ ú∫ uƒÀowo ∫ı\ Nz F|áåÁı N˛ÁzÀƒyN˛Á∫ N˛∫z EÁ{∫ ÃÀoz tÁ™ ú∫ F|áå §{b∫y F¬zMb~ÁzgÁı Á∫Á

TÏmƒÁ Ã“ÁÆoÁ “ÁF|g~Áz\å Ãz ÆÏMo T{Ã Ãu©™»m N˛ÁzGnúëÁ N˛∫ ÃNz oÁuN˛ F|áå §{b∫y u§\¬y Ãßy ÀsÁåÁı ú∫Gú¬£á N˛y \Á ÃNz @ gÁ}.LÃ.EåÊo, uåtzΔN˛, ßÁ∫oyÆüÁ{ ÁzuTN˛y ÃÊÀsÁå, åF| ut®y Á∫Á FÃ Ãzu™åÁ∫ N˛Á GtΩVÁbå“ÏEÁ@ gÁ}.\z.LÃ.ÆÁtƒ, uåtzΔN˛, EÁF| EÁF| Ãy by åz FÃGtΩVÁbå Ã™Á∫Áz“ N˛y EÜÆqoÁ N˛y@

12. åÁÆÏg©™Á À™Á∫N˛ uN¿ Nz b bÓåÁ|™zzÊb -12-14 utÃ©§∫,2003

FÃ bÓåÁ|™ıb ™ı uå©åu¬uQo by™Áı åz ßÁT u¬ÆÁ:

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åÁußN˛yÆ F|áå Ãu©™», “{t∫Á§Át

uƒrÁå ƒ üÁ{ ÁzuTN˛y uƒßÁT, åF| ut®y

úÆÁ|ƒ∫m ƒ ƒå uƒßÁT, åF| ut®y

EÁ¬ FÊugÆÁ Ãy.LÃ.EÁF|.EÁ∫.by™

ßÁ∫oyÆ ™Á{Ã™ uƒrÁå uƒßÁT, åF| ut®y

F¬zMb~ÁuåN˛ N˛Á∫úÁz∫zΔå G˘ÁzT u¬u™bzg, “{t∫Á§Át

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12 utÃ©§∫, 2003 N˛Áz FÃ tÓåÁ|™ıb Nz GtΩVÁbå Ã™Á∫Áz“N˛Á EÁÆÁz\å uN˛ÆÁ TÆÁ@

gÁ}.\z.LÃ.ÆÁtƒ åz FÃ Ã™Á∫Áz“ N˛y EÜÆqoÁ N˛y EÁ{∫»y ∫ÁNz Δ NÏ ™Á∫ Δ™Á|, üΔÁÃå uåÆÊfiN˛ åz uƒußëÁ uN¿ Nz bby™Áı N˛Á ÀƒÁTo uN˛ÆÁ@ uN¿ Nz b ™{Y YÁ∫ utåÁı oN˛ Y¬z@úÆÁ|ƒ∫m ƒ ƒå uƒßÁT, åF| ut®y FÃ bÓåÁ|™ıb N˛Á uƒ\zoÁ∫“Á@ Ã™Áúå Ã™Á∫Áz“ N˛Á EÁÆÁz\å §gz ú{™Áåz ú∫ uN˛ÆÁTÆÁ@ »y. ∫ÁNz Δ NÏ ™Á∫ Δ™Á|, ÃÊÆÁz\N˛ åz áãÆƒÁt üÀoÏouN˛ÆÁ@

13. Nw˛ufi™ §ÏuÚ™noÁ ú∫ üs™ ßÁ∫oyÆ EÊo∫Á|…b~yÆÃ©™z¬å (EÁF| EÁF| Ãy L EÁF| - 03) - 18-20utÃ©§∫, 2003.

EÁF|.EÁF|.Ãy.by. ™ı Æ“ Ã™Á∫Áz“ utÃ©§∫ 18-20, 2003N˛Áz EÁÆÁzu\o uN˛ÆÁ TÆÁ osÁ EÁF|.EÁF|.Ãy.by., EÁF|.F|.F|.F|.uÃÀb©Ã, ™{å LÊg ÃÁF§∫åzubMÃ ÃÁzÃÁFby (ÆÓ.LÃ.L.): ÃÓYåÁüN¿ ™ “zoÏ EÊo∫Á|…b~yÆ ÃÊV (EÁÀbz~u¬ÆÁ), EÁF| EÁz LÃ üzÃ(åzt∫¬¯g) osÁ ÃÁ}¢ Ωb N˛©õÆÓubÊT ú∫ uƒ≈ƒ ÃÊV (\ÁúÁå)


7

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14. gÁ}.úy.LÃ.™Óuo| À™Á∫N˛ ßÁ m osÁ ∫ÁÃÁÆuåN˛EußÆÁÊufiN˛y ú∫ EÁF|.EÁF|.Ãy.by. “y∫N˛ \ÆÊoyÃzu™åÁ∫ - 10 \åƒ∫y, 2004.

ÃÊÀsÁå Nz ∫ÁÃÁÆuåN˛ EußÆÁÊufiN˛y üßÁT åz ‘∫ÁÃÁÆuåN˛EußÆÁÊufiN˛y-ƒ{u≈ƒN˛ YÏåÁ{uoÆÁÂ’ uƒ Æ ú∫ LN˛ utƒÃyÆ∫Á…b~yÆ Ãzu™åÁ∫ 10 \åƒ∫y, 2004 N˛Áz EÁÆÁzu\o uN˛ÆÁ@FÃ Ãzu™åÁ∫ Nz EÁÆÁz\å N˛Á ™ÏPÆ GtΩtz≈Æ G˘ÁzT, ∫Á…b~yÆüÆÁzTΔÁ¬ÁEÁı osÁ Δ{uqN˛ ÃÊÀsÁåÁı ™ı N˛ÁÆ|∫o ∫ÁÃÁÆuåN˛EußÆÊoÁEÁzÊ Nz §yY uƒYÁ∫Áı N˛Á EÁtÁå ütÁå EÁ{∫ ∫ÁÃÁÆuåN˛EußÆÁÊufiN˛y Nz qzfi ™ı EÁáÏuåN˛ EåÏÃÊáÁå ƒ uƒN˛ÁÃ NzÃ©§ãá ™ı Geåz ƒÁ¬y EÁúÃy Ã™ÀÆÁEÁı ú∫ uƒYÁ∫ uƒ™Δ|N˛∫åz Nz u¬L LN˛ ™ÊY Gú¬£á N˛∫ÁåÁ sÁ@ Ãzu™åÁ∫ ™ÏPÆo:EåÏüÆÏMo H…™ÁTuoN˛y, EußuN¿ ÆÁ EußÆÁÊufiN˛y ™Ázgu¬ÊTosÁ uÃ™Ï¬zΔå, tÁåztÁ∫ útÁsÁz N˛Á §“Áƒ osÁ üN¿™ ÃÏ∫qÁNz EÁáÏuåN˛ qzfi FnÆÁut uƒ ÆÁı ú∫ sÁ@ FÃ Ãzu™åÁ∫ NzoN˛åyN˛y Ãfi ™ı ∫ÁÃÁÆuåN˛ EußÆÁÊufiN˛y Nz qzfi ™ı uƒußëÁuƒΔz rÁı ˚Á∫Á EÁ™Êufio ßÁ m EÁÆÁzu\o uN˛Æz TÆz@ 8 ƒÁÂúy. LÃ. ™Óuo| À™Á∫N˛ EußßÁ m gÁ}.gy.LÃ. uƒ≈ƒåÁs,Lu™u∫bÃ üÁz¢z Ã∫, u™ÀÃÁz∫y uƒ≈ƒuƒ˘Á¬Æ, N˛Áz¬u©§ÆÁ, ÆÓLÃ L åz utÆÁ@

15. N˛y™ÁzFÊ¢˛∫™zubMÃ Nz EÁ{ ÁzuTN˛ GúÆÁzT osÁ N˛©õÆÓb∫Ã“ÁÆN˛ EÁ { á ug„\ÁFå-∫Á…b ~yÆ N˛ÁÆ |ΔÁ¬Á12-17 \åƒ∫y, 2004

ÃÊÀsÁå åz Gú∫ÁzMo uƒ Æ ú∫ 12-17 \åƒ∫y, 2004N˛Áz Z: utƒÃyÆ ∫Á…b~yÆ N˛ÁÆ|ΔÁ¬Á N˛Á EÁÆÁz\å uN˛ÆÁ@G˘ÁzT Ãz 13 Δ{uqN˛ ÃÀsÁåÁı Ãz 13 EÁ{∫ ∫Á…b~yÆüÆÁzTΔÁ¬ÁEÁzÊ Ãz 4 üuoßÁuTÆÁı åz FÃ™ı ßÁT u¬ÆÁ@∫ÃÁÆåΔÁÀfi, \yƒ uƒrÁå, ∫ÁÃÁÆuåN˛ FÊ\yuåÆu∫ÊT osÁuYuN˛nÃÁ EÁut uƒußëÁ qzfiÁı ™ı N˛ÁÆ| N˛∫åzƒÁ¬z üuoßÁTyFÃ Ãzu™åÁ∫ ™ı ΔÁu™¬ “ÏL@ Ãßy Z: utåÁı oN˛ EÁmuƒN˛

™Ázgu¬ÊT ƒ GÃNz √ÆÁƒ“Áu∫N˛ LƒÊ Ã{ÚÁÊuoN˛ ú“¬ÏEÁzÊ ú∫üN˛ÁΔ gÁ¬Á TÆÁ@ FÃ N˛ÁÆ|ΔÁ¬Á ™ı ™ÏPÆ §Áo Æ“ ∫“y N˛yü{uMbN˛¬ (“{ãgΩÃ - EÁå) bz~uåÊT ú∫ uƒΔz ÜÆÁå utÆÁ TÆÁEÁ{∫ üuoßÁuTÆÁı N˛Áz Ãßy ÃÁ°bƒzÆ∫ Ãy. gy. Nz øú ™ıuƒou∫o uN˛Æz TÆz@

16. ∫Á…b~yÆ uƒrÁå utƒÃ Ã™Á∫Áz“ - 28 ¢˛∫ƒ∫y, 2004

EÁÂá¿ ützΔ uƒrÁå ƒ üÁ{ ÁzuTN˛y úu∫ tΩ, “{t∫Á§Át NzÃ“ÆÁzT Ãz 28 ¢˛∫ƒ∫y, 2004 N˛Áz Æ“ Ã™Á∫Áz“ EÁÆÁzu\ouN˛Æz TÆz@ Ã∫ Ãy ƒy ∫Á™å Á∫Á ∫Á™å üßÁƒ Nz Eãƒz mN˛y VÁz mÁ N˛y À™wuo ™ı ünÆzN˛ ƒ | ∫Á…b~yÆ uƒrÁå utƒÃÃ™Á∫Áz“ N˛Á EÁÆÁz\å uN˛ÆÁ \ÁoÁ “{@ gÁ}.úy. ∫Á™Á ∫Áƒ,Ã¬Á“N˛Á∫, uƒrÁå ƒ üÁ{ ÁzuTN˛y osÁ GÄÁ uΔqÁ FÃ Ã™Á∫Áz“Nz ™ÏPÆ Euous ∫“z@ üÁz. Ãy. ÃÏ£§Á ∫Áƒ, EÜÆq, EÁÂá¿ ützΔ∫Á[Æ GÄÁ uΔqÁ úu∫ tΩ åz FÃ Ã™Á∫Áz“ N˛y EÜÆqoÁ N˛y@

17. 12 ƒÁÂ ΔÁÊuo Àƒøú À™Á∫N˛ EußßÁ m - 1 Eü{¬,2004

gÁ}. (»y™oy). ™Ê\Ó Δ™Á|, uƒrÁå ƒ üÁ{ ÁzuTN˛y ™ÊfiyN˛y Ã¬Á“N˛Á∫, ßÁ∫o Ã∫N˛Á∫ åz 12 ƒÁÂ ΔÁÊuo Àƒøú À™Á∫N˛EußßÁ m, 1 Eü{¬, 2004 N˛Áz utÆÁ@ gÁ}. Δ™Á| åz <ÆÁzSÆ\{ƒ-ßuƒ…Æ N˛y EÁz∫ EÊo∫uƒ Æy EåÏÃÊáÁå Nz §yY Ã“uN¿ÆÁ-\{ƒ üÁ{ ÁzuTN˛y ™ı G˘™Δy¬oÁ osÁ √ÆÁúÁ∫yN˛∫m> uƒ Æú∫ À¢Óuo|tÁÆN˛ EußßÁ m utÆÁ@ §“Ïo §‰gy ÃÊPÆÁ ™ıƒ{rÁuåN˛, uƒ≈ƒuƒ˘Á¬Æ Nz EÜÆÁúN˛ LƒÊ ZÁfi osÁ EãÆÃÊÀsÁå Nz ¬ÁzTÁı åz ßÁ m N˛Áz ÃÏåÁ.

18. ∫Á…b~yÆ üÁ{ ÁzuTN˛y utƒÃ - 11 ™F|, 2004

ƒ | 11 ™F| 1998 N˛Áz ßÁ∫o åz úÁÊY ú∫™ÁmÏ ú∫yqmuN˛Æz osÁ ú∫™ÁmÏ M¬§ ™ı ÃtÀÆoÁ üÁõo N˛∫ ¬y@ FÃutƒÃ N˛Áz ünÆzN˛ ƒ | ∫Á…b~yÆ üÁ{ ÁzuTN˛y utƒÃ Nz øú ™ı™åÁÆÁ \ÁoÁ “{ EÁ{∫ EÁF|.EÁF|.Ãy.by. ßy ünÆzN˛ ƒ | FÃutƒÃ N˛Áz ™åÁoÁ “{@ FÃ ƒ | üÁ{ ÁzuTN˛y utƒÃ ßÁ m,gÁ.L.N˛y. ∫Á™Á∫Áƒ, ßÓoúÓƒ| uåtzΔN˛, EÁF|. EÁF|. Ãy. by. åzutÆÁ@ EÁF.LÃ.EÁz. T¿Á“N˛Áı Nz ÃÁs LN˛ ™yubÊT N˛Á ßyEÁÆÁz\å “ÏEÁ@

19. GnNw˛…eoÁ N˛y o¬ÁΔ ™ı ƒ∫YÏE¬ƒ∫YÏE¬ƒ∫YÏE¬ƒ∫YÏE¬ƒ∫YÏE¬ u∫ÆÁ¬by ú∫Ãzu™åÁ∫ 4-5 \Óå, 2004.

ƒ∫YÏE¬ u∫ÆÁ¬by (Virtual Reality) Nz qzfi ™ı ÃÊÆÊfi

“y∫N˛ \ÆÊoy Ã™Á∫Áz“ (ETÀo 5, 2003 Ãz ETÀo 4, 2004)

8

ÆÁz\åÁEÁzÊ Ãz ¬zN˛∫ “ƒÁF| \“Á\ uÃ™Ï¬z m osÁ gÁF™ıΔåTzu™ÊT oN˛ uƒN˛ÁÃ “ÏEÁ “{@ ƒ∫YÏE¬ u∫ÆÁ¬by LN˛ Gß∫oy“ÏF| üÁ{ ÁzuTN˛y “{ u\ÃN˛y uƒÀowo q™oÁ N˛Á GúÆÁzT ¬TßTÃßy ƒ{rÁuåN˛ qzfiÁı ™zÊ “ÁzoÁ “{ @ u¢˛∫ ßy FÃ N˛Á uƒN˛ÁÃEuáN˛o∫, EåÏÃÊáÁå osÁ Tzu™ÊT oN˛ “y Ãyu™o “{ EÁ{∫uåÆu™o EÁ{ ÁzuTN˛ GúÆÁzT oN˛ FÃN˛Á tÁÆ∫Á Eßy ¢{ ¬Áå“Î “{ @

FÃ Ãzu™åÁ∫ N˛Á GtΩtz≈Æ ÃÁ™ÁãÆ \åoÁ oN˛ FÃüÁ{ ÁzuTN˛y N˛Áz ú“ÏÊYÁåz N˛y ÃÊßÁƒåÁEÁı ú∫ uƒYÁ∫ N˛∫åÁosÁEåÏÃÊáÁå ƒ uƒN˛ÁÃ ÃÊÀsÁå, Δ{uqN˛ ÃÊÀsÁå, ∫qÁ,G˘ÁzT osÁ Ã∫N˛Á∫ Nz ÃÁs - ÃÁs T{∫ - Ã∫N˛Á∫y L\ıuÃÆÁıNz uƒΔz rÁı osÁ üÆÁzMoÁEÁı Nz §yY uƒYÁ∫ uƒ™Δ| N˛∫ƒÁåÁsÁ @

gÁ}. EÁ∫. Lå. uÃÊ“, uåtzΔN˛ T¿zg ƒ{rÁuåN˛, Lå.\y.EÁ∫.EÁF|., “{t∫Á§Át åz FÃ Ãzu™åÁ∫ N˛Á GtΩVÁbå uN˛ÆÁ @ FÃÃzu™åÁ∫ ™ı 5 oN˛åyN˛ Ãfi ΔÁu™¬ sz @ FÃ™ı EÁ™ÊuÊfioEußßÁ mÁzÊ Nz ÃÁs-ÃÁs 21 ¬zQ üÀoÏo uN˛Æz TÆz @EÁF|.EÁF|.Ãy.by. ˚Á∫Á ∫ÁÃÁÆuåN˛ G˘ÁzT ™zÊ ƒ∫YÏE¬u∫Æu¬by Nz GúÆÁzT ú∫ Z: ¬zQ üÀoÏo uN˛Æz TÆz @

20. 14ƒÁÂ uÃÚÓ uƒrÁå EußßÁ m - 2 \Ï¬ÁF| 2004

üÁz. LÃ. Nz . §¿“Ω™YÁ∫y, uåtzΔN˛, \yåÁzu™N˛ ƒ Ã™T¿\yƒ uƒrÁå, åF| ut®y åz <LÃLåúy, uYõÃ, FÊ¢˛∫™zubMÃLƒÊ ßuƒ…ÆƒÁmy uYuN˛nÃÁ> uƒ Æ ú∫ ΔÏN¿ ƒÁ∫, 2 \Ï¬ÁF|,2004 N˛Áz LÃ.§y.“Á}¬, Lå.\y.EÁ∫.EÁF|. Gõú¬ ∫Ázg,“{t∫Á§Át ™ı EußßÁ m utÆÁ@

ƒ | 1981 ™ı gÁ}.\y.LÃ.uÃÚÓ ÀsÁúåÁ ãÆÁÃ N˛Á EÁ∫ÊßGåNz F…b u™fiÁı EÁ{∫ Ã“ÆÁzuTÆÁı Á∫Á uN˛ÆÁ TÆÁ@ FÃ ãÆÁÃNz uN¿ ÆÁN˛¬ÁúÁı ™ı Ãz LN˛ Æ“ “{ uN˛ GåNz \ã™ utå ú∫ƒ{rÁuåN˛ uƒ ÆÁı ú∫ uƒuΔ…b ƒ{rÁuåN˛Áı ˚Á∫Á EußßÁ mÁzN˛Á EÁÆÁz\å “ÁzoÁ “{@

21. EÁF|.EÁF|.Ãy.by. “y∫N˛ \ÆÊoy Ã™Áúå Ã™Á∫Áz“ -4 ETÀo, 2004

ßÁ∫oyÆ ∫ÁÃÁÆuåN˛ üÁ{ ÁzuTN˛y ÃÊÀsÁå, “{t∫Á§Át ™ı“y∫N˛ \ÆÊoy Ã™Áúå Ã™Á∫Áz“ N˛Á EÁÆÁz\å 4 ETÀo,2004 N˛Áz “ÏEÁ@ »y. N˛uú¬ uÃ£§¬, ™ÁååyÆ ∫Á[Æ ™Êfiy(ÀƒoÊfi YÁ\|), uƒrÁå ƒ üÁ{ ÁzuTN˛y osÁ Ã™Ï uƒN˛ÁÃ,ßÁ∫o Ã∫N˛Á∫ osÁ GúÁÜÆq, Ãy.LÃ.EÁF|.EÁ∫., FÃÃ™Á∫Áz“ Nz ™ÏPÆÁuous ∫“z@


»y. uÃ£§¬ åz Eúåz “y∫N˛ \ÆÊoy EußßÁ m ™ı N˛“ÁuN˛ Ãy.LÃ.EÁF|.EÁ∫. N˛Áz 21 ƒÎ Ãty ™ı üÁ{ ÁzuTN˛yÆ N¿ ÁÊuoN˛Áz EÁTz §‰jÁåÁ “{@ üÁ{ ÁzuTN˛yÆ åƒyN˛∫mÁı N˛y q™oÁ N˛yú“YÁå osÁ ßuƒ…Æ ™ı Gå üÁ{ ÁzuTuN˛ÆÁı N˛Áz üÆÁzTΔÁ¬Á Ãz§Á„\Á∫ ™ı ¬Áåz Nz u¬L EÊo∫ uƒ Æy Ã“ÆÁzT osÁ ƒ{rÁuåN˛Ã™ÏtÁÆ ™ı Ã“ßÁuToÁ Euo EÁƒ≈ÆN˛ “{@ »y. uÃ£§¬ åzƒ{rÁuåN˛Áı Ãz EÁ“ΩƒÁå uN˛ÆÁ uN˛ ƒz T∫y§y ∫zQÁ Ãz åyYz¬TßT 70 N˛∫Áz‰g ßÁ∫oyÆ \åoÁ Nz u¬Æz ßÁz\å, EÁƒÁÃosÁ ÀƒÀ·Æ ÃÏ∫qÁ ™Ï“{ÆÁ N˛∫ÁÆı@

gÁ}.EÁ∫.L. ™ÁΔz¬N˛∫, ™“ÁuåtzΔN˛, Ãy.LÃ.EÁF|.EÁ∫.åz N˛“Á uN˛ uƒrÁå ƒ üÁ{ ÁzuTN˛y qzfi ™ı tzΔ åz Ã∫Á“åyÆN˛ÁÆ| uN˛ÆÁ “{ osÁ Ãy.LÃ.EÁF|.EÁ∫. ™ı EÁ¬Á ÃÊÀsÁå “ÁzåzNz åÁoz EÁF|.EÁF|.Ãy.by. åz ∫ÃÁÆåΔÁÀfi osÁ ∫ÁÃÁÆuåN˛üÁ{ ÁzuTN˛y Nz qzfi ™ı EúåÁ ™“nƒúÓm| ÀsÁå §åÁ u¬ÆÁ “{@Gã“Áıåz ƒ | 2005 Ãz EÁ∫Êß “Ázåz ƒÁ¬z úzbıb ΔÁÃå Nz ÃÊtß|™ı tzΔ ™ı åƒyå GnúÁtÁı N˛y EÁƒ≈ÆN˛oÁ ú∫ §¬ utÆÁ@EÁ∫Êß ™ı gÁ}.\z.LÃ.ÆÁtƒ, uåtzΔN˛, EÁF|.EÁF|.Ãy.by. åzƒ{rÁuåN˛Áı, uΔ¡úuƒrÁuåÆÁı, Δ{uqN˛ ÃÊÀsÁå ƒ G˘ÁzT NzÃtÀÆÁı osÁ EÁF|.EÁF|.Ãy.by. Nz N˛™|YÁu∫ÆÁı Ãz ÆÏMo §w“oÃßÁ N˛Á ÀƒÁTo uN˛ÆÁ EÁ{∫ “{t∫Á§Át Nz uå„\Á™ Nz ¢˛∫™Áå˚Á∫Á ÃÊÀsÁå Nz EÁ∫Êß Ãz ¬zN˛∫ ƒ | 1989 ™ı ßÁ∫oyÆ∫ÁÃÁÆuåN˛ üÁ{ ÁzuTN˛y ÃÊÀsÁå Nz øú ™ı úÏå: åÁu™oüÆÁzTΔÁ¬Á Nz uƒN˛ÁÃ osÁ ƒ | 1994 ™ı GÃN˛y Àƒm| \ÆÊoyoN˛ N˛y ÆÁfiÁ ú∫ üN˛ÁΔ gÁ¬Á@ FÃ EƒÃ∫ ú∫ »y N˛uú¬uÃ£§¬ åz À™Áu∫N˛Á N˛Á uƒ™ÁzYå uN˛ÆÁ EÁ{∫ EÁF|.EÁF|.Ãy.by.Nz ÃzƒÁuåƒwno ƒ N˛ÁÆ|∫o ƒ{rÁuåN˛Áı N˛Áz Ã©™Áåúfi ütÁåuN˛ÆÁ @ EåzN˛ ßÓoúÓƒ| uåtzΔN˛Áı LƒÊ EÁF|.EÁF|.Ãy.by. NzT¿Á“N˛Áı åz üÆÁzTΔÁ¬Á Nz ÃÁs Eúåz ÃÊ§ÊáÁı ƒ N˛ÁÆ| ú∫üN˛ÁΔ gÁ¬Á@ gÁ}.L.Ãy.NÂ Ïƒ∫. uåtzΔN˛ T¿zg ƒ{rÁuåN˛ åz áãÆƒÁtüÀoÁƒ üÀoÏo uN˛ÆÁ@

™ÁååyÆ ™Êfiy \y åz EÁF|.EÁF|.Ãy.by. “y∫N˛ \ÆÊoyÀ™Á∫N˛ N˛Á GtΩVÁbå uN˛ÆÁ EÁ{∫ FÃ EƒÃ∫ ú∫ LN˛ úÁ{áz N˛Á∫Ázúm uN˛ÆÁ@ Gã“Áıåz \yƒ üÁ{ ÁzuTN˛y osÁ \yƒ üuƒuá Nı ¸osÁ EÁz úy Ãy g£¡ÆÓ ú∫yqm üÆÁzTΔÁ¬Á N˛Á ßy GtΩVÁbåuN˛ÆÁ@ “Á¬ “y ™ı uƒN˛uÃo å{åÁz™zubu∫Æ¬ uƒrÁå üÆÁzTΔÁ¬Á,\ÊoÏ MƒÁ∫ÊbÁFå ÃÏuƒáÁ osÁ üÁNw uoN˛ GnúÁt ∫ÃÁÆåΔÁÀfiüÆÁzTΔÁ¬Á N˛Áz ßy tzQÁ@

9

Sixty years is a long period in the life of an R&D

institution. It is a momentous occasion when the

institution has to pause to recall the struggles and

efforts of its founding fathers and those who have

contributed in many ways to the growth of the

institution.

To celebrate the Diamond Jubilee, an IICT Diamond

Jubilee Celebrations Apex Committee was constituted

in the month of March 2003 along with various

subcommittees. Curtain raiser ceremony was held on

August 5, 2003. The Apex Committee along with the

Chairmen of various Sub-committees first met on April

9, 2003 under the chairmanship of Dr.K.V.Raghavan, the

then Director, to draw a tentative plan for year-long

celebrations covering scientific, cultural and social

events. The Apex Committee met several times during

the year and reviewed the progress. Dr.J.S.Yadav took

over as Chairman of the Apex Committee on 1st October

2003 and held several meetings to discuss the

arrangements of the Diamond Jubilee celebrations. The

various events conducted during the diamond jubilee

year are outlined below:

Curtain Raiser - August 5, 2003Curtain Raiser - August 5, 2003Curtain Raiser - August 5, 2003Curtain Raiser - August 5, 2003Curtain Raiser - August 5, 2003

The Curtain Raiser for the IICT Diamond Jubilee (1944-

2004) Celebrations was held on August 5, 2003 and the

IICT Diamond Jubilee logo was unveiled. Dr. Masami

Inada, President, M/s Aisin Cosmos, Japan was the Chief

Guest. IICT signed agreements with M/s Aisin Cosmos

(Japan), KCP (Hyderabad) and K. N. Biotech (Hyderabad)

on this occasion. A cultural programme was held in the

evening.

Independence Day Indoor SportsIndependence Day Indoor SportsIndependence Day Indoor SportsIndependence Day Indoor SportsIndependence Day Indoor Sports - August 15, August 15, August 15, August 15, August 15,20032003200320032003

The Independence Day IICT Diamond Jubilee Indoor

Sports meet for the employees and their family

members was held and the following events were

conducted :

Badminton (Men & Women)

Carrom (Men & Women)

Table Tennis (Men & Women )

Chess

Track and field events for the residents of the

staff quarters

National Seminar on National Seminar on National Seminar on National Seminar on National Seminar on ‘‘Recent R & D TrendsRecent R & D TrendsRecent R & D TrendsRecent R & D TrendsRecent R & D Trendsin Rice Bran Oil Processing and By-Productin Rice Bran Oil Processing and By-Productin Rice Bran Oil Processing and By-Productin Rice Bran Oil Processing and By-Productin Rice Bran Oil Processing and By-ProductUtilizationUtilizationUtilizationUtilizationUtilization”- August 30, 2003- August 30, 2003- August 30, 2003- August 30, 2003- August 30, 2003

Lipid Science & Technology Division along with the Oil

Technologists’ Association of India (Southern Zone)

organized a one-day National Seminar on “ Recent R&D

Trends in Rice Bran Oil Processing and By-product

Utilization” on August 30, 2003. Dr. K.V. Raghavan,

Director, IICT presided at the seminar. The seminar was

dedicated to the memory of Dr.K.T.Achaya – a well

known oil technologist and former Head of Oils & Fats

Division of IICT. Shri V.Sobhanadreeswara Rao,

Honourable Minister, Department of Agriculture, Govt.

of Andhra Pradesh inaugurated the seminar. The

Honourable Minister also handed over agreements of

MoU signed by the IICT with Ganapati Solvex Pvt. Ltd.,

Rajnandgaon and Mecpro Heavy Engineering Ltd., New

Delhi for the establishment of 50 tonnes per day rice

bran oil refineries with the grant-in-aid assistance from

TMOP & M, Govt. of India. The first two sessions were

devoted to the discussion on the recent R&D trends in

rice bran oil processing and by-product utilization. A

distinguished panel of speakers discussed the various

topics related to prospects of rice bran oil technology

upgrading during the third session of the seminar. The

seminar was sponsored by Technology Mission on

Oilseeds, Pulses and Maize, Ministry of Agriculture, Govt.

of India and Council of Scientific & Industrial Research,

DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004)DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004)DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004)DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004)DIAMOND JUBILEE CELEBRATIONS (AUGUST 5, 2003 TO AUGUST 4, 2004)

During the curtain raiser, seen from left to right : Dr. J.S. Yadav,Director, Dr. K.V. Raghavan Ex. Director & Dr. M. Inada

10

New Delhi and co-sponsored by M/s Muez Hest Process

Technologies Pvt. Ltd., Mumbai. The convener of the

seminar was Dr. R.B.N. Prasad, Deputy Director and Head,

Lipid Science & Technology Division.

Teachers Day Celebrations - September 5,Teachers Day Celebrations - September 5,Teachers Day Celebrations - September 5,Teachers Day Celebrations - September 5,Teachers Day Celebrations - September 5,20032003200320032003

The IICT Diamond Jubilee Teachers Day Celebrations

were organized jointly by IICT and AP Akademi of

Sciences on 5th September 2003. A special talk was

delivered by Prof. N.Satyamurthy, Dean, Faculty Affairs,

IIT, Kanpur and scientific sessions were conducted for

the benefit of students by Prof. P. K. Sai Prakash, Hon.

Secretary, A. P. Academy of Sciences and Dr. Ratan F.

Toorkey, Polymer Chemist, EMRC, CIEFL, Hyderabad.

children and members of staff who participated in

various Hindi competitions. A scientific National Seminar

in Hindi “Rasayan evam jeev vigyan ke antarbindu”,

organized in connection with the Diamond Jubilee of

IICT was inaugurated by Prof.C.Subba Rao, Chairman, A.

P. State Council for Higher Education. About nine papers

were presented in Hindi supported by multi-media done

in Hindi. Dr. S.E.Hasnain, Dr. K.V. Raghavan, Dr.Usha

Goswami, Dr.Annapurna, Dr.V.K.Rao, Dr.V.K.Saxena,

Dr.Ishratullah Dr.D.Shailaja were some of the scientists,

who presented their papers in Hindi. Some of the topics

presented in the seminar were : Chemistry Biology

Interface, Traditional Indian Drugs, Globalization-New

Dimensions, Cell-A Chemical Factory, Pest Management

in Groundnut with Controlled Release of Polymers- New

Dimensions. The programme concluded with a Hindi

comedy “Beemar Koun” staged by the staff of the

Institute.

Hindi Day Celebrations - September 15, 2003Hindi Day Celebrations - September 15, 2003Hindi Day Celebrations - September 15, 2003Hindi Day Celebrations - September 15, 2003Hindi Day Celebrations - September 15, 2003

On the occasion of the Hindi day, celebrations took place

on September15, 2003 in collaboration with CDFD. Prof.

Mukul Chand Panday, Member, Hindi Advisory

Committee, Home Ministry, Govt. of India was the chief

guest. Dr. K. V. Raghavan, the then Director of IICT,

welcomed the gathering. In his welcome address, Dr.

Raghavan outlined the Hindi language implementation

activities involving scientists and administrators.

Dr.Syed E. Hasnain, Director, CDFD appreciated the steps

taken by both the Institutes and suggested the

scientists to write scientific articles in Hindi. In his Hindi

Day message, Prof. Pandey suggested various simple

steps to further the implementation of the Official

Language. The chief guest gave away the prizes to the

International Seminar on International Seminar on International Seminar on International Seminar on International Seminar on ‘‘Global Scenario ofGlobal Scenario ofGlobal Scenario ofGlobal Scenario ofGlobal Scenario ofHerbal MedicineHerbal MedicineHerbal MedicineHerbal MedicineHerbal Medicine” - September 19 - SeptemberSeptember 19 - SeptemberSeptember 19 - SeptemberSeptember 19 - SeptemberSeptember 19 - September20, 200320, 200320, 200320, 200320, 2003

The seminar was jointly organised by IICT, IGNA and

Max Muller Bhavan, Chennai at IICT on Sept. 19 – 20,

2003. The seminar received good attention from

researchers, academicians, medical practitioners,

students and industrialists from the Pharma sector. The

seminar was inaugurated by Dr. C. K. Kokate, Vice

Chancellor, Kakatiya University. In his inaugural address

Prof. Kokate stressed the need for the development of

herbal-based medicines for the benefit of the society,

which India once pioneered in ancient times. Dr (Mrs) E

Teachers Day Celebrations at IICT

The Chief Guest is welcomed during the Hindi Seminar


11

Rahimi, Director, MMB presided over the inaugural

function. Prof. Hermann PT Ammon, Professor Emeritus,

Pharmacology and Toxicology, University of Tuebingen,

Germany delivered a keynote lecture “ Boswellia serrata

from an ayurvedic medicine to a modern drug -

pharmacological and clinical studies” and gave an

excellent exposition on transformation of Boswellia

serrata to a modern herbal drug that is clinically proven.

Eminent speakers drawn from various sections involved

in the herbal drugs development shared their

experiences on diverse topics starting from history of

herbal drug development, standardisation of herbal

medicines, development of herbal nutraceuticals, safety

of the herbal drugs to opportunities in natural products.

Dr J.M Rao, Deputy Director, Natural Products Division

of IICT gave a lecture on application of scientific methods

towards scientific development of herbal medicines. The

seminar was followed by a panel discussion that

debated key issues raised during the course of the

seminar. The panel of experts included, Dr Sanjeeva Rao,

Ex-Drug Controller, Dr. K. V. Raghavan, the then Director

of IICT, Prof. HPT Ammon, Emeritus Professor, Dr T.S.S.

IICT Diamond Jubilee Initiatives - SeptemberIICT Diamond Jubilee Initiatives - SeptemberIICT Diamond Jubilee Initiatives - SeptemberIICT Diamond Jubilee Initiatives - SeptemberIICT Diamond Jubilee Initiatives - September21, 200321, 200321, 200321, 200321, 2003

Dr. R. A. Mashelkar, Director General, CSIR & Secretary,

DSIR (GOI) inaugurated the “IICT Diamond Jubilee

Initiatives” on September 21, 2003 at IICT. Prof. R. Kumar,

Chairman, IICT Research Council presided. Some of the

highlights of the function are given below:

Inauguration of new research laboratories in the

renovated main building

Inauguration of the incident control centre for

chemical accident mitigation

Inauguration of reforestation and green belting of

IICT campus

Launch of ENVIS centre

Release of IICT HRD Document

Presentation of Diamond Jubilee Mementos to IICT

staff and research scholars

Release of IICT special postal cover commemorating

the diamond jubilee of IICT by Shri T. S. Govindrajan,

Chief Post Master General, A. P. Region

Diamond Jubilee address by Dr. R. A. Mashelkar

IICT’s evolution in six decades by Dr. K. V. Raghavan

Scientific presentations

Dixit, Consultant, Pharmacology Evaluation and Dr. J.M.

Rao, Head, Natural Products Division, IICT. It was

unanimously accepted that it is highly essential to work

towards understanding the therapeutically active part

of medicinal plants. A great emphasis was laid on

establishing analytical standards at various levels

without deviating from the philosophical concepts. The

Co-ordinators of the seminar were : Dr. J. S. Yadav, Shri

K.V.R.S. Murthy and Dr. Prakash V. Diwan of IICT.

International Seminar ‘Global Scenario of Herbal Medicine’

Dr. R.A. Mashelkar, DGSIR is presented with the special postalcover released on the occasion of Diamond Jubilee

Diamond Jubilee Celebrations (August 5, 2003 to August 4, 2004)

12

CSIR Foundation Day - September 26, 2003CSIR Foundation Day - September 26, 2003CSIR Foundation Day - September 26, 2003CSIR Foundation Day - September 26, 2003CSIR Foundation Day - September 26, 2003

a. This was celebrated on September 26, 2003 at IICT.

The Guest of Honour was Prof.Y. Venkatarami Reddy,

Vice Chancellor, JNTU, Hyderabad. Some of the

highlights are given below:

Presidential Address by Director, IICT

Unveiling of Biotechnology Incubator Designs

Presentation of mementos to staff members

completing 25 years of service

Honouring of retired staff members

Research papers publication awards to JRF/SRF

Dr. R. N. Sarma Memorial Award for JRF and Shri

Gopalakrishna Rao Vepachedu Memorial Award for

SRF

Award of certificates to MS Chemical Technology

students of BITS, Pilani

Declaration of studentships to children of staff who

secured admission in Indian Institute of Technology

(IIT)

Presentation of cash awards to children of staff who

scored more than 90% marks in each of the three

science subjects in the XII standard examination. On

this occasion, the IICT Diamond Jubilee Sports Award

Function was also held. Shri Arshad Ayub, ex-

member of Indian cricket team was the Guest of

Honour. Dr. K. V. Raghavan, the then Director of IICT,

spoke on the occasion highlighting the sports

activities in IICT. Awards were presented to IICT

sportsmen by the chief guest.

K.T. Achaya Memorial Lecture - October 1,K.T. Achaya Memorial Lecture - October 1,K.T. Achaya Memorial Lecture - October 1,K.T. Achaya Memorial Lecture - October 1,K.T. Achaya Memorial Lecture - October 1,20032003200320032003

The lecture was the first Diamond Jubilee event under

the leadership of Dr. J. S. Yadav who took over as Director

on 1st October, 2003. The Indian Institute of Chemical

Technology and Oil Technologists’ Association of India,

Southern zone decided to organize a memorial lecture

every year on Dr. Achaya’s birthday, as a fitting tribute

to his outstanding contributions to the growth of Indian

oils & fats R & D. The K.T. Achaya Memorial lecture was

delivered by Dr.P. M.Bhargava, a close associate of Dr.

K.T. Achaya on October 6, 2003 in the IICT Auditorium.

Dr. J. S. Yadav welcomed the participants and introduced

the speaker to the audience. Dr. Vijay Kale, President

OTAI (SZ) informed about the genesis of K. T. Achaya

Endowment Fund instituted by the OTAI and how the

finances would be raised. The short biodata of Dr.K. T.

Achaya was read out to the august audience which is

given below:

Dr. Konganda Thammu Achaya was born on October 6,

1923 at village Kolligil in the state of Tamil Nadu. After

completing his educational pursuits in 1950, he joined

the laboratory and was associated with the Institute till

1971. As deputy Director and Head of Oils and Fats

Division, he built the school of Lipid Chemistry and

Technology. Dr. Achaya, a doyen in the field of Oils and

Fats, was honoured with several national and

international awards. Dr. Achaya breathed his last on

September 5, 2002. Dr.K.V.Raghavan, Director Grade

Scientist, spoke about his association with Dr. Achaya

and the achievements of Dr. Achaya. Dr. P. M. Bhargava

paid tributes to Dr.Achaya and then delivered the First

K. T. Achaya Memorial Lecture on “The Relationship

between Science and Arts”. Dr.Bhargava in his

presentation lucidly explained the intricate relationship

and symmetry between art and science. He kept the

audience spell bound with his presentation. The

meeting ended with a vote of thanks by Dr. B.V.S.K.Rao,

Honorary Secretary, OTAI (SZ). On this occasion, the

renovated second floor of the main building of IICT,

named as K. T. Acharya Wing, was declared open by

Padmabhushan Dr. P.M.Bhargava, Founder Director of

CCMB.

Dr. P.M. Bhargava is garlanding the photo of Dr. Achaya


13

IICT FounderIICT FounderIICT FounderIICT FounderIICT Founder’s Day Lecture- November 7,s Day Lecture- November 7,s Day Lecture- November 7,s Day Lecture- November 7,s Day Lecture- November 7,20032003200320032003

The lecture was on the topic “New Dimensions to NMR

Applications: Disease Diagnosis, Treatment, Monitoring

and Direct Social Relevance” was delivered on Friday, 7th

November 2003 by Dr. C. L. Khetrapal, FNA &

Distinguished Professor, Centre for Biomedical Magnetic

Resonance, Sanjay Gandhi P.G.Institute of Medical

Sciences, Lucknow. Dr. J. S. Yadav, Director, IICT presided

over the function.

‘‘UNESCO Regional Training Workshop onUNESCO Regional Training Workshop onUNESCO Regional Training Workshop onUNESCO Regional Training Workshop onUNESCO Regional Training Workshop onEnvironmental ChemistryEnvironmental ChemistryEnvironmental ChemistryEnvironmental ChemistryEnvironmental Chemistry’’- November 10 -- November 10 -- November 10 -- November 10 -- November 10 -November 15, 2003November 15, 2003November 15, 2003November 15, 2003November 15, 2003

The workshop was held from November 10 to

November 15, 2003. This residential Workshop - cum -

Training Course on Environmental Chemistry was

sponsored by UNESCO Regional Centre, Delhi for the

teaching faculty from India and neighbouring countries

like Sri Lanka, Bangladesh and Nepal. 18 Participants

from all over India and 4 from Sri Lanka, one each from

Bangladesh and Nepal attended the Workshop. It was

inaugurated by Dr. A. C. Kunwar, Incharge Director of

IICT and Dr. K. V. Raghavan, Director Grade Scientist of

IICT delivered the Inaugural Lecture on “Green

Technologies”. Experts from IICT, Jawaharlal Nehru

Technological University (JNTU), Environmental

Protection Training Research Institute (EPTRI),

Patancheruvu Environmental Tech. Ltd (PETL) and M/s

Sarvotham Chemicals delivered 16 lectures on different

topics viz., air, water and soil pollution, ecology, safety,

hazard treatment & risk assessment technologies by

physical, chemical and biological methods, sampling

techniques, phytoremediation etc. The participants were

taken to environmental facilities of JNTU, PETL & EPTRI

for exposing them to latest state of art facilities in

environmental chemistry. At the Valedictory Function

on 15th November, 2003, Dr.J.S. Yadav, Director, IICT

presented certificates to the participants. Dr. M. S. Alam,

Senior Programme Specialist - Science, UNESCO, New

Delhi, was the Chief Guest. The Course Coordinator, Dr.

M. Vairamani, Deputy Director & Head, Analytical

Chemistry Division, summarized the proceedings of

the course.

National Seminar National Seminar National Seminar National Seminar National Seminar ‘‘ Fuel To Fuel Cells Fuel To Fuel Cells Fuel To Fuel Cells Fuel To Fuel Cells Fuel To Fuel Cells’’ - - - - -December 4-5, 2003December 4-5, 2003December 4-5, 2003December 4-5, 2003December 4-5, 2003

The seminar which was held on Dec. 4-5, 2003 was co-

sponsored by the Ministry of Non-conventional Energy

Sources. Dr. K B S Prasad, Head, Coal, Gas & Energy

Division, IICT, Hyderabad introduced about the seminar

and its importance. In the present scenario with

increased awareness on the levels of carbon emissions,

the fuel cell technology has assumed great relevance

globally as substitute to conventional power

generation for all applications. The fuel processor must

be small, have high reforming efficiency, give hydrogen

of high purity and must not be expensive. To achieve

this, it must feature extensive integration between heat

and mass transfer, chemical reactions and impurity

removal. It is a task which presents the designers and

manufacturers unusual challenges, that is evading

solution. The overall challenge, therefore, is to achieve

a fully integrated fuel processing system, which accepts

a wide range of fuels at normal levels of purity and

produces a hydrogen rich gas mixture of quality

tolerated by the fuel cell electrodes at an affordable

cost so that fuel cell power becomes widespread and

common. The issues connected with R&D support,

Government’s role, codes & standards, commercial

financing, infrastructure and time scale of development

were identified as critical for the development of this

technology. The seminar was inaugurated by Prof.

M.S.Ananth, Director, Indian Institute of Technology,

Delhi. Dr. R K Bhattacharya, General Manager, Corporate

R&D, BHEL, Hyderabad gave the Keynote Address. The

two-day seminar was divided into five Technical

Sessions, a Panel Discussion, an IICT Session and a

Concluding Session. Dr. J S Yadav, Director, IICT presided

over the Inaugural Function. Among the eminent

speakers of the seminar were: Prof. B Viswanathan, Head,

Department of Chemistry, IIT, Madras, Prof. Basu, IIT, Delhi,

Dr. Devotta, Director, NEERI, Nagpur, Dr. K V Raghavan,

former Director, IICT, Hyderabad, Dr. H S Maiti, Dierctor,

CGCRI, Kolkata, Dr. V V Krishnan, University of


14

Pennsylvania, USA, Dr. V M Desai, E I DuPont India Ltd.,

Gurgaon, Dr. K S Dhathathreyan, formerly, SPIC Science

Foundation, Madras, Mr. Sidhartha Sen, GAIL, New Delhi

and Mr R K Kashyap, GAIL, New Delhi. Dr.M

Subrahmanyam, Scientist, Catalysis, IICT proposed a

vote of thanks.

Nayudamma Memorial Cricket Tournament

December 12- December 14, 2003

It was organized from December 12 to December 14,

2003. The following teams participated in the

tournament:

Department of Information Technology

Nuclear Fuel Complex, Hyderabad

Department of Science and Technology, New

Delhi

Department of Environment and Forests, New

Delhi

All India CSIR Labs

Indian Meteorological Department, New Delhi

Electronics Corporation Industries Limited,

Hyderabad

CSIR Laboratories of Hyderabad

Anand, Vice-President, Hyderabad Cricket Association

and Assistant Commissioner of Police, Hyderabad. The

cricket matches were held for four days on knock–out

basis in the IICT cricket ground. The winner of the

tournament was the Department of Environment and

Forests, New Delhi. The closing ceremony was arranged

in a grand way in front of the main building and the

chief guest was Shri Ranga Reddy, President, Hyderabad

Cricket Association. The vote of thanks was proposed

by Shri R.K. Sharma, Convener of the event.

The First Indian International Conference onThe First Indian International Conference onThe First Indian International Conference onThe First Indian International Conference onThe First Indian International Conference onArtificial Intelligence (IICAI-03)Artificial Intelligence (IICAI-03)Artificial Intelligence (IICAI-03)Artificial Intelligence (IICAI-03)Artificial Intelligence (IICAI-03)’’-December 18-December 18-December 18-December 18-December 18-20, 2003-20, 2003-20, 2003-20, 2003-20, 2003

The inaugural function was held on 12 December 2003.

It was presided over by Dr. J. S Yadav, Director, IICT. Shri R.

K Sharma, COA welcomed the various cricket teams to

IICT. The tournament was inaugurated by Shri C.V.

The conference was held in IICT from December 18 -

December 20, 2003 and was co-sponsored by IICT, IEEE

Systems, Man and Cybernetics Society (USA);

International Federation for Information Processing

(Australia); IOS Press ( The Netherlands) and World

Federation on Soft Computing (Japan). Dr. JS Yadav,

Director, IICT inaugurated the conference and

highlighted the importance of artificial intelligence and

its applications in various fields. Dr. USN Murty, Head,

Biology Division spoke on the genesis of the conference

and the possible applications of artificial intelligence in

controlling the vector borne diseases. 126 Papers were

presented in 18 sessions during the three-day

conference. Biocomputing and Bioinformatics session

attracted the attention of many scientists. The

conference was successfully concluded on December

20, 2003.

Shri C.V. Anand (Right) is inaugurating the NayudammaCricket Tournament

Inauguration of the ‘IICAI-03’ by Dr. J.S. Yadav, Director


15

Dr. P. S. Murti Memorial Lecture and IICTDr. P. S. Murti Memorial Lecture and IICTDr. P. S. Murti Memorial Lecture and IICTDr. P. S. Murti Memorial Lecture and IICTDr. P. S. Murti Memorial Lecture and IICTDiamond Jubilee Seminar on ChemicalDiamond Jubilee Seminar on ChemicalDiamond Jubilee Seminar on ChemicalDiamond Jubilee Seminar on ChemicalDiamond Jubilee Seminar on ChemicalEngineering - January 10, 2004Engineering - January 10, 2004Engineering - January 10, 2004Engineering - January 10, 2004Engineering - January 10, 2004

The Chemical Engineering Division of the Institute

organized a one-day National Seminar “Chemical

Engineering–Global Challenges” on January 10, 2004.

The basic objective of this seminar was to provide a

forum for the chemical engineers working in industry,

national laboratories and academic institutions to

exchange ideas and discuss problems of mutual interest

to advance R&D in frontier area of chemical engineering.

The focus of the seminar was on the frontier areas of

Applied Thermodynamics, Reaction Engineering,

Modeling and Simulation, Flow of Granular Materials

and Process Safety. The seminar theme included

technical sessions with invited lectures by various

experts the field of Chemical Engineering. These lectures

include, the 8th P.S. Murti Memorial Lecture delivered by

Dr. D.S. Viswanath, an Emeritus Professor at the

University of Missouri, Columbia, USA, followed by

special lectures by eminent chemical engineers like Dr.

K.V. Raghavan, former Director of IICT, Dr. B.D. Kulkarni,

Director Grade Scientist and Head of the Chemical

Engineering Division at the National Chemical

Laboratory, Pune, Professor D.V. Khakhar of the Indian

Institute of Technology, Mumbai, and Sri. V.V. Bhujle of

Ciba-Geigy Pvt. Ltd, Mumbai. The seminar had also a

Panel Discussion. About 200 delegates from industry,

academy and R&D institutions participated in the

seminar.

National Workshop on National Workshop on National Workshop on National Workshop on National Workshop on ‘‘Industrial ApplicationsIndustrial ApplicationsIndustrial ApplicationsIndustrial ApplicationsIndustrial Applicationsof Chemoinformatics and Computer Aidedof Chemoinformatics and Computer Aidedof Chemoinformatics and Computer Aidedof Chemoinformatics and Computer Aidedof Chemoinformatics and Computer AidedDrug DesignDrug DesignDrug DesignDrug DesignDrug Design” - January 12 to January 17, - January 12 to January 17, - January 12 to January 17, - January 12 to January 17, - January 12 to January 17,20042004200420042004

Molecular Modeling Group, Organic-I division organized

a six-day national workshop on “Industrial applications

of chemoinformatics and computer aided drug design”

from January 12 to January 17, 2004. It had about 13

participants from Industry, 13 from academic institutes

and 4 from national laboratories. The participants were

from various backgrounds, such as chemistry, biology,

computer science, chemical engineering and medicine.

Among the faculty, there were 5 each from Industry

and Universities and 8 from national laboratories. All

the six-days, the participants were exposed to the

molecular modeling and its practical and theoretical

aspects. It was an intensive, brainstorming and a

thought-provoking workshop dealing with most of the

multifaceted aspects of chemoinformatics and

computer-aided drug design. An important feature of

the workshop was that it occupied almost 50% of the

time schedule on hands-on sessions. In addition to the

brochure of all the invited lectures, forty (40) interesting

papers running into 400 pages were photocopied and

given to all the participants. Most of the publicly

available software packages were put in a CD and

distributed among the participants.

National Science Day Celebrations - FebruaryNational Science Day Celebrations - FebruaryNational Science Day Celebrations - FebruaryNational Science Day Celebrations - FebruaryNational Science Day Celebrations - February28, 200428, 200428, 200428, 200428, 2004

The celebrations were held on February 28, 2004 in

collaboration with A.P. Council of Science and

Technology, Hyderabad. National Science Day is

celebrated every year on February 28 to commemorate

the announcement of the discovery of Raman effect

by Sir C.V. Raman. Dr. P. Rama Rao, Adviser, S&T and Higher

Education was the chief guest at the function which

was presided over by Prof. C Subba Rao, chairman, AP

State Council for Higher Education. Prof. J. M. Naidu

spoke about the importance of the National Science

Day followed by the address of Dr. A. C. Kunwar, Incharge

Director, IICT. On this occasion, the Andhra Pradesh

Scientist Award was presented to Dr. B.M. Choudary,

National Science Day Celebrations - 2004


16

Representative, ISO 9001:2000 Quality Management

System welcomed the participants. Dr. J. S.Yadav,

Director, IICT, in his opening remarks, gave a brief

description of various research and analytical activities

at IICT. Dr. A. C. Kunwar, Director grade Scientist, made a

detailed presentation on the analytical facilities at IICT.

Sri A. Krishna Reddy, Scientist-In-Charge, Pilot Plants

made a brief presentation on pilot plant facilities

available at IICT. Twenty two representatives from

various industries participated in the meeting. They had

direct interaction with the Director, Dr.A.C.Kunwar, Dr .

Shakunthala Madhavendra, Dr. Md. Kifayatullah and

Scientists–in-Charge of various analytical centres. The

meeting was quite useful in getting information for

improving the scope and quality of analytical services.

Seminar on Virtual Reality in Pursuit ofSeminar on Virtual Reality in Pursuit ofSeminar on Virtual Reality in Pursuit ofSeminar on Virtual Reality in Pursuit ofSeminar on Virtual Reality in Pursuit ofExcellence - June 4-5, 2004Excellence - June 4-5, 2004Excellence - June 4-5, 2004Excellence - June 4-5, 2004Excellence - June 4-5, 2004

Developments were made in Virtual Reality (VR)

technology ranging from walk throughs in plant layout

to aircraft simulations and 3D gaming. Virtual reality is

an emerging technology, which has wide potential with

applications in almost all the scientific fields. However,

the developments were mostly confined to research

and gaming rather than any regular industrial

applications. This seminar aimed to bring experts and

users from R&D Institutes, Academic Institutes, Defence,

Industry and Government as well as Non-Governmental

agencies to discuss various possibilities of bringing this

technology to the common man. The seminar was

inaugurated by Dr R N Singh, Director’s Grade Scientist,

NGRI, Hyderabad. The seminar consisted of five technical

scientist, IICT by the special invitee Dr. A. V. Rama Rao,

Chairman & Managing Director, AVRA Laboratories in

recognition of his significant contributions to science

and technology. Vote of thanks was proposed by Mrs. C.

B. Lakshmi, Head, Research Management.

Dr. Manju Sharma is garlanding the photo of Dr. S.S. Bhatnagar

12th S.S.Bhatnagar Memorial Lecture - April12th S.S.Bhatnagar Memorial Lecture - April12th S.S.Bhatnagar Memorial Lecture - April12th S.S.Bhatnagar Memorial Lecture - April12th S.S.Bhatnagar Memorial Lecture - April1, 20041, 20041, 20041, 20041, 2004

On April1, 2004 the 12th S.S.Bhatnagar Memorial Lecture

was delivered by Dr. (Mrs) Manju Sharma, Adviser to

Minister for Science and Technology, Government of

India. Dr. Sharma gave a scintillating lecture on the topic

‘Towards a Sustainable Biofuture-A Synergy between

Interdisciplinary Research, Entrepreneurship and

Commercialisation in Biotechnology”

National Technology Day - May 11, 2004National Technology Day - May 11, 2004National Technology Day - May 11, 2004National Technology Day - May 11, 2004National Technology Day - May 11, 2004

India conducted five nuclear tests on May 11, 1998 and

joined the Nuclear Club. This day is celebrated as

National Technology Day and IICT too celebrates the

day every year.

a)a)a)a)a) National Technology Day lecture- 2004National Technology Day lecture- 2004National Technology Day lecture- 2004National Technology Day lecture- 2004National Technology Day lecture- 2004

On this ocassion, Padmashree Dr. A. V. RamaRao

delivered the National Technology Daylecture-2004. The

topic of the lecture was “Process Chemistry - Can an

academic lend fresh perspective to the subject?”

b)b)b)b)b) Interactive Meeting with ISO ClientsInteractive Meeting with ISO ClientsInteractive Meeting with ISO ClientsInteractive Meeting with ISO ClientsInteractive Meeting with ISO Clients

An interactive meeting with ISO clients was held on

May 11, 2004 as part of Technology Day Celebrations.

Dr. Shakunthala Madhavendra, Management

Dr. A.V. Rama Rao, CMD, AVRA Labs is welcomed byDr. J.S. Yadav, Director, IICT


17

sessions spread over one and a half days. About 98

members participated in the seminar. The first technical

session dealing with concepts reality, started with an

invited speech on “Virtual reality an advanced tool of

visualization and digital prototype” delivered by an

exponent in virtual reality technologies, Shri K

Raghuram, Senior Deputy General Manager, BHEL

Corporate R&D, Hyderabad. Dr CRJ Prakash Naidu, a

stalwart from Defence Organization Centre for Artificial

Intelligence and Robotics, Bangalore delivered an

invited speech on “Current application of Virtual Reality

and Technologies Trends”. Dr.K Ramanathan, Scientist G,

ADA, Bangalore spoke on “Virtual Reality Prototyping

Technologies in the development of LCA”. The discussion

started with the development of flight simulators,

interest of NASA in the development of flight simulators

and molecular modeling. Major aspects of Virtual Reality

such as Software, Database, Objects, Geometry Creation,

Objects in VR Environment & VR Environment were

Efficient usage of MSDS using VR

Virtual Library is an Information tool for

scientists

VR Training for inspection staff of TAC/ Fire

Fighting personnel for hazardous occupancies

Virtual Welding, Myth or Reality

Virtual Environment Training

Agitation Systems

14th Sidhu Science Lecture - July 2, 200414th Sidhu Science Lecture - July 2, 200414th Sidhu Science Lecture - July 2, 200414th Sidhu Science Lecture - July 2, 200414th Sidhu Science Lecture - July 2, 2004

It was delivered by Professor S. K. Bramhachari, Director,

Institute of Genomics and Integrative Biology, New Delhi

on SNPs, Chips, Informatics and Predictive Medicine, on

Friday, the July 2, 2004 at S. B. Hall, National Geophysical

Research Institute, Uppal Road, Hyderabad.

Dr. G. S.Sidhu Foundation Trust was founded in the year

1981 by some of his close associates. One of the activities

of the Trust is to organize lectures by eminent scientists

on topics of scientific interest to coincide with his

birthday. Thirteen such lectures have already been

organised till date hosted by the Indian Institute of

Chemical Technology.

IICT Diamond Jubilee Valedictory Function -IICT Diamond Jubilee Valedictory Function -IICT Diamond Jubilee Valedictory Function -IICT Diamond Jubilee Valedictory Function -IICT Diamond Jubilee Valedictory Function -August 4, 2004August 4, 2004August 4, 2004August 4, 2004August 4, 2004

Indian Institute of Chemical Technology, Hyderabad

organised its Diamond Jubilee Valedictory Function on

discussed. The invited lectures were of Dr Manjunath, a

scientist of NRSA, Hyderabad, on “Fly – 3D Terrain

Visualization Software”; Prof.C Kameswar Rao of Deccan

College of Engineering, on “Patenting Trends in Virtual

Prototyping”. Prof. P J Narayanan from IIIT, Hyderabad

discussed in detail the Modeling languages. Besides the

above invited lectures, 21 papers were presented on

the applications of Virtual Reality. IICT presented the

following on applications of Virtual Reality in Chemical

Industry :

Prof. Bramhachari is delivering the lecture


Dr.J.S.Yadav, Director, IICT is welcoming the chief guest duringthe Seminer on Virtul Reality in Pursuit of Excellence

18

August 4,2004. Shri Kapil Sibal, Hon’ble Minister of State

(Independent charge), S&T and Ocean Development,

Govt. of India and Vice-President, CSIR was the chief

guest. Shri Sibal, in his Diamond Jubilee address, said

that Council of Scientific & Industrial Research (CSIR)

should forge technological revolution in the 21st

century. Inter-disciplinary co-operation and partnerships

in the scientific community were most important to

realize the potential of technological innovations and

facilitate their transfer from the laboratories to the

market in the coming days. Shri Sibal asked the

scientists to focus on technology that would ensure

food, shelter, healthcare and education to the 700 million

people of the country whose monthly earnings are less

than $2 a day (Rs.3000/- per month). He explained that

if we did not touch the lives of these people, technology

will be of no use. While land productively was decreasing,

population was on the rise. He reminded the scientific

community to solve some of these complex problems

of the people. The Minister assured the scientists that

autonomy of scientific institutions like IICT would be

protected.

Dr. R.A.Mashelkar, Director General, CSIR said that

country had done well in the science and technology

and IICT had created a niche for itself in the field of

chemistry and chemical technology, being a Diamond Shri Kapil Sibal is addressing the gathering during D.J. function

in the CSIR chain. He stressed the need for coming with

newer products in the wake of the patent regime to be

introduced from 2005. He said that the laboratories

should adopt to the emerging ambience and new

reforms should take the country in the path of progress.

Earlier, Dr. J.S.Yadav, Director, IICT welcomed the huge

gathering comprising of scientists, technologists,

members from academia and industry and IICT staff

members and explained in detail the growth of the

laboratory in the past sixty years, right from its inception

on 5th August 1944 through the Firman of Nizam of

Hyderabad to its renaming as Indian Institute of

Chemical Technology in 1989 and its Golden Jubilee in

1994. On this occasion, Shri Kapil Sibal released the

Diamond Jubilee Souvenir and presented ‘Role of

Honour’ to retired and working scientists of IICT. A

number of former Directors and IICT clients recalled

their association and the works done at the laboratory

earlier. Dr.A.C.Kunwar,Director Grade Scientist proposed

a vote of thanks.

The Hon’ble Minister inaugurated the IICT Diamond

Jubilee monument and planted a sapling on this

occasion. He also inaugurated the Biotechnology and

Bioprocessing Centre and OPCW test lab in the Mass

Spectrometry Centre. He visited the newly developed

Nanomaterials Science Laboratory, Animal Quarantine

Facilities and Natural Products Chemistry Laboratory.

Hon’ble Minister Shri Kapil Sibal is releasing the Souvenir


21

CSIR conceived and identified around 56 Network

Programmes / Projects for implementation during 10th

Five Year Plan (2005-07) by networking among CSIR

laboratories. Based on the expertise and competence

available with CSIR Laboratories and specific role to be

performed by different CSIR Labs, DG has constituted

Task Force Network Project / Programme on Developing

Green Technologies for Organic Chemicals (CMM-0006)

and Globally Competitive Chemicals, Processes (COR-

0003) with Director, IICT as Chairman and IICT as Nodal

Laboratory. The other members / participating

laboratories with regard to CMM-0006 are Directors or

their nominees of CECRI, CFRI, CIMAP, IIP, NCL, NEERI, RRL

(Jorhat), RRL (Tri.), RRL (Jam), RRL (Bhu), CSMCRI, IHBT

along with representatives and a senior scientist of CSIR

Hqrs. The other members / participating labs with

regard to COR-0003 are Directors or their nominees of

CFRI, CIMAP, IIP, NCL, NEERI, RRL (Tri), RRL (Jam), RRL (Bhu),

CSMCRI, IHBT along with representative and a senior

scientist of CSIR Hqrs.

Participating laboratories identified 26 projectcomponents under Development of Green Technologiesfor Organic Chemicals covering areas like (a) Greenprocesses for medicinal plants (b) Value added productsfrom bio-mass and agro industrial wastes (c) Alkylationand oxidation of aromatic compounds (d)Fluoroorganics and (e) Novel mesophorous nanomaterials and 16 project components were identifiedunder Globally Competitive Chemicals and Processescovering the areas like (a) Functional and natural dyesefficiency processes for bio-actives (b) Novel Ti-TiO

2

processes and (c) Alternative fuels/fine chemicals.

Various project components along with participatinglaboratories are given in Fig. 1 and Fig. 2.

i) Developing Green Technologies for OrganicChemicals (CMM-0006)

ii) Globally Competitive Chemicals, Processes andProducts (COR - 0003)

Output of the following networking projects during2003-05 are given in table 1 & 2. IICT outputs are alsogiven in respective R&D sections and other participatinglaboratories may be reporting in their annual reports.

CSIR NETWORK PROJECTSCSIR NETWORK PROJECTSCSIR NETWORK PROJECTSCSIR NETWORK PROJECTSCSIR NETWORK PROJECTS

Dr. A.V. Rama Rao, CMD, AVRA Labs and former Director,IICT & Dr. J.S. Yadav, Director IICT (right) are seen during the

Network Projects Meeting.

Meeting in Progress

22

Biennial Report 2003-2005 F

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23

Fig. 2

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CSIR Network Projects

24


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25

CSIR Network Projects1

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•Des

ign

, in

stal

lati

on

op

erat

ion

an

dev

alu

atio

n o

f p

erfo

rman

ce o

fb

ench

sca

le u

nit

s fo

r g

ener

atio

n o

fp

roce

ss p

aram

eter

s vi

z.en

viro

nm

enta

l co

nd

itio

ns.

Dev

elo

pm

ent

of

gre

en p

roce

sses

,va

lue

add

ed p

rod

uct

s, o

rgan

icch

emic

als

fro

m b

iom

ass.

Lab

ora

tory

sc

ale

sy

nth

esi

s o

fp

her

om

on

e co

mp

on

ents

IV a

nd

V is

succ

ess

full

y co

mp

lete

d i

n t

hre

est

ages

i.e.

on

2g

m b

atch

siz

e, 1

0gm

bat

ch s

ize

, an

d 2

5g

m b

atch

siz

e.

Syn

the

sis

and

up

sca

lin

g o

f th

ep

roce

ss t

ech

no

log

y fo

r p

her

om

on

eco

mp

on

ents

I, II

an

d II

I is

com

ple

ted

on

50

gm

bat

ch s

ize.

Diff

eren

t ty

pes

of

mar

ket

avai

lab

le d

isp

ense

rs w

ere

pro

cure

d a

nd

th

e p

roce

du

res

for

pre

-tre

atm

ent

wer

e st

and

ard

ized

.

Ben

ch s

cale

un

it f

erm

enta

tio

n u

nit

cou

ple

d w

ith

mem

bra

ne

syst

em h

asb

een

in

stal

led

. Th

e p

rod

uct

ion

of

Lact

ic a

cid

usi

ng

iso

late

d N

LS9

cult

ure

usi

ng

hyd

roly

zed

po

tato

was

te w

as t

aken

up

an

d t

he

syst

emh

as b

een

op

tim

ized

fo

r se

lect

ion

of

en

viro

nm

en

tal

(pH

an

d

tem

pe

-ra

ture

) co

nd

itio

ns

L –

Lac

tic

acid

pro

du

ctio

n u

sin

gca

ssav

a b

iog

ases

th

rou

gh

var

iou

sfe

rmen

tati

on

pro

cess

es.Is

ola

ted

few

po

ten

t cu

ltu

res

cap

able

o

fp

rod

uci

ng

Gam

ma

lin

ole

nic

aci

dfr

om

ch

eap

ly a

vaila

ble

ag

ro b

ased

bio

mas

s.

Scal

ing

up

the

pro

cess

in b

ench

sca

leb

iore

acto

r.

-

-

1 (-

)

1 (-

)

-

-

2 (-

)

-

-

26

Biennial Report 2003-20053.

1A

lkyl

atio

n o

f A

rom

atic

Co

mp

ou

nd

s

3.2

Oxi

dat

ion

s o

f Aro

mat

icC

om

po

un

ds

4.1

Flu

oro

O

rga

nic

sTri

flu

oro

eth

an

ol

He

lta

flu

oro

p

rop

an

e

(FM

20

0)i

. Ch

emic

al ro

ute

ii.El

ectr

o c

hem

ical

1,1

,1-

trif

luo

ro-2

,2-d

ich

loro

eth

an

e

(HF

CF

C-1

23

)D

iflu

or

om

eth

an

e(H

FC-3

2) I

ICT

4.2

Mes

op

oro

us

mat

eria

ls

5.1

Gas

Sto

rag

e m

ater

ials

5.2

Me

tha

ne

to

v

alu

ead

ded

pro

du

cts

5.3

Org

anic

Sil

icat

es

To d

evel

op

an

act

ive,

sel

ecti

ve a

nd

stab

le c

atal

yst

for

alky

lati

on

of

nap

hth

alen

e an

d p

hen

ol

Oxi

dat

ion

o

f p

-xyl

en

e

to

tere

-p

hth

alic

ac

idO

xid

atio

n

of

met

hyl

amis

ole

.

Syn

thes

is o

f nan

o s

tru

ctu

red

car

bo

n,

carb

on

co

vere

d m

eso

po

rou

s si

lica

Fun

ctio

nal

izat

ion

of

silic

ates

.

Larg

e p

ore

zeo

lite

bas

ed c

atal

ysts

and

mix

ed o

xid

e ca

taly

sts

hav

e b

een

pre

par

ed b

y m

od

ifica

tio

n w

ith

met

alim

pre

gn

atio

n a

nd

th

eir

acti

viti

esh

ave

bee

n e

valu

ated

fo

r al

kyla

tio

no

f n

aph

thal

en

e a

nd

ph

en

ol

wit

hen

cou

rag

ing

res

ult

s an

d c

atal

ysts

hav

e b

een

ch

arac

teri

zed

by

XR

D,

SEM

an

d s

urf

ace

area

an

alys

is

A n

ew s

trat

egy

for

pre

par

atio

n o

fte

re-p

hth

alic

aci

d b

y o

xid

atio

n o

f p

-xy

len

e in

aq

ueo

us

med

ia

Op

tim

ize

d

the

p

roce

ss

and

dem

on

stra

ted

to

in

du

stry

i.O

pti

miz

ed p

roce

ss d

evel

op

edan

d b

ein

g d

emo

nst

rate

dii.

Perf

luo

rois

ob

uty

ric

acid

is m

ade

by

Elec

tro

Ch

emic

al F

luo

rin

atio

n(5

Kg

)La

b s

cale

pro

cess

dev

elo

ped

Lab

scal

e pr

oces

s und

er d

evel

op m

ent

Met

han

e ab

sorp

tio

n s

tud

ies

carr

ied

.

Pre

par

ed

M

o

and

W

ca

rbid

ep

rom

ote

d Z

SM-5

an

d e

valu

ated

fo

rd

ehyd

roar

om

atis

atio

n o

f m

eth

ane

to b

enze

ne

and

hyd

rog

en

4 (-

)

-

-

2 (-

)2

(2)

-

5 (-

)2

(1)

1 (-

)

* Fi

gu

res

in b

rack

ets

ind

icat

es o

vers

eas.

27

Tab

le (2

):C

SIR

NET

WO

RK

ED P

RO

JEC

T O

N “

GLO

BA

LLY

CO

MP

ETIT

IVE

CH

EMIC

ALS

PR

OC

ESSE

S A

ND

PR

OD

UC

TS”

Pro

ject

Co

de:

CO

R -0

003

Nam

e o

f th

e A

ctiv

ity

Maj

or

Del

iver

able

s d

uri

ng

20

05

-06

Pro

gre

ss m

ade

till

20

05

Pap

ers

Pat

ents

1.1

.Tis

sue

C

ult

ure

a

nd

Pro

cess

ing

of

Nat

ura

lD

yes

1.2

Fun

ctio

nal

Dye

s

Stu

dy

the

C

om

po

siti

on

fo

ro

pti

miz

atio

n o

f cu

ltu

re m

edia

and

scr

een

ing

an

d s

elec

tio

n o

fTi

ssu

e o

r O

rgan

of

Ind

igo

fera

pla

nt

for

syn

the

sis

and

loca

liza

tio

n o

f In

dic

am i

n i

tsti

ssu

e. U

se A

bio

tic

and

Bio

tic

elic

ito

rs t

o e

nh

ance

syn

thes

is o

fin

dic

am

�To

d

eve

lop

p

roce

ssin

gte

chn

olo

gy

for

the

pro

du

ctio

n o

f xa

nth

op

hyl

ld

ye f

rom

tag

etes

ere

cta

�T

issu

e

cult

ure

o

f p

anax

sikk

ime

nsi

s fo

r th

ep

rod

uct

ion

of

red

Pig

men

t.

Cal

li w

ere

form

ed f

rom

all

the

five

typ

es o

f in

ocu

lum

pla

nt t

issu

es in

the

thre

e b

asal

me

dia

. R

ate

of

call

ifo

rmat

ion

w

as

in

the

o

rde

r;n

od

e>

inte

rno

de

>le

af>

lea

fla

min

a>ro

ot.

Aft

er 2

/3 m

on

ths

of

gro

wth

on

ag

ar-

gel

led

med

ium

th

eca

lli t

urn

ed b

row

m. T

he

cell

lines

hav

e b

een

pre

serv

ed f

or

assa

y o

fin

dig

o t

in. n

atu

re a

nd

tex

ure

of

calli

we

re d

ocu

me

nte

d a

nd

use

d f

or

bio

syn

thes

is o

f in

dig

oti

n. T

he

bas

alm

ed

ium

is

en

rich

ed

wit

h h

igh

er

con

cen

trat

ion

o

f in

org

anic

ph

osp

hat

e,

cyto

kin

in a

nd

GA

3 t

oin

du

ce f

aste

r g

row

th r

ate

of

cells

un

der

su

spen

sio

n c

ult

ure

.

Pro

cess

kn

ow

-ho

w f

or

xan

tho

ph

yll

dye

fro

m T

ere

cta

flo

wer

s 50

Ger

mp

lasm

a ac

cess

ion

s w

ere

cult

ivat

ed &

the

fl

ow

ers

o

bta

ine

d

we

rep

roce

sse

d

for

xan

tho

ph

yll

esti

mat

ion

, ran

ges

bet

wee

n 0

.059

to

2.06

%. F

resh

T e

rect

a flo

wer

s (1

0 K

g)

wer

e p

rod

uce

d i

n o

ur

exp

erim

enta

lfa

rm, L

uck

now

.Pro

cess

for e

xtra

ctio

n;

iso

lati

on

of

cru

de

dye

up

to

5 K

gfr

esh

flo

wer

s b

asis

was

dev

elo

ped

.Ev

alu

atio

n

of

T

ere

cta

inm

ult

iloca

tio

n tr

ails

is b

ein

g ta

ken

up

.B

ench

sca

le e

xtra

ctio

n p

roce

ss f

or

the

dye

fro

m t

he

cult

ure

d c

ells

(30

gle

vel)

is b

ein

g s

tan

dar

diz

ed.

-

--

-

--

New

Nat

ura

l an

d F

un

ctio

nal

Dye

s

Tech

.Tra

ns


28


2.1

Bro

min

ati

on

/He

ck/

Ca

rbo

xy

lati

on

to

ob

tain

ch

ira

lm

ole

cule

s

2.2

Co

mp

lex

d

yn

am

icp

roce

ss,

asy

mm

etr

icsy

nth

esi

s fo

r ch

ira

ld

rug

s/in

term

edia

te

2.3

No

vel r

eact

ion

med

ia

3.1

Vap

ou

r p

has

e p

roce

ssfo

r T

iO2 &

Ele

ctro

lyti

cre

du

ctio

n o

f TiO

2

Inve

stig

atio

ns

on

Hec

k re

acti

on

sw

ith

al

read

y sy

nth

esi

zed

cata

lyst

s w

ill

be

ca

rrie

do

ut.H

eter

og

eneo

us

cata

lyst

s fo

rH

eck

reac

tio

ns

will

be

targ

eted

.

Sca

le-u

p t

ech

no

log

y fo

r th

esy

nth

esis

of T

axo

l sid

e ch

ain

an

dD

ilti

aze

m b

y m

ult

ifu

nct

ion

alca

taly

sts

in 2

0g s

cale

is in

itia

ted

in a

sso

ciat

ion

wit

h a

pri

vate

firm

.

Pre

par

atio

n,

Ch

arac

teri

zati

on

and

eva

luat

ion

of T

iO2 e

lect

rod

e.La

bo

rato

ry s

cale

stu

die

s o

nd

irec

t el

ectr

oly

tic

red

uct

ion

of

TiO

2.C

12

re

cove

ry f

rom

HC

L,al

tern

ate

reac

tor

con

figu

rati

on

s,m

od

elin

g o

f ch

lori

nat

ion

reac

tor.

Ear

lie

r a

set

of

ho

mo

ge

ne

ou

sca

taly

sts

are

sy

nth

esi

zed

an

dst

ud

ied

fo

r h

eck

re

acti

on

. N

ew

pal

lad

ium

cat

alys

ts o

n b

iop

oly

mer

sup

po

rts

are

sy

nth

esi

zed

an

dp

erfo

rmed

mo

del

Hec

k re

acti

on

s.

As

per

th

e si

gn

ed a

gre

emen

t w

ith

ap

riva

te f

irm

fo

r u

p s

calin

g o

f Ta

xol

sid

e ch

ain

an

d d

iltia

zem

usi

ng

th

esu

pp

ort

ed c

atal

ysts

, la

b s

cale

wo

rkfo

r Ta

xol

sid

e ch

ain

is

fin

ish

ed a

nd

de

mo

nst

rati

on

to

th

e I

nd

ust

ry i

sco

mp

lete

d.

Lab

sca

le w

ork

on

th

eD

iltia

zem

is

un

der

pro

gre

ss.

New

cat

alys

ts a

re s

ynth

esiz

ed a

nd

pre

limin

ary

test

s o

n M

ich

ael a

dd

itio

nh

ave

bee

n c

arri

ed o

ut.

C-C

an

d C

-Nco

up

ling

reac

tio

ns

in io

nic

liq

uid

s ar

ecu

rren

tly

un

der

in

vest

igat

ion

.

Tita

niu

m o

xid

e el

ectr

od

es h

ave

bee

np

rep

ared

fro

m c

hem

ical

gra

de

TiO

2

and

so

me

Ch

arac

teri

zati

on

stu

die

sh

ave

bee

n i

nit

iate

d. E

lect

roly

tic

cell

syst

em

su

itab

le f

or

con

du

ctin

gex

per

imen

ts in

a m

uff

le fu

rnac

e w

asse

t up

an

d e

xper

imen

tati

on

init

iate

d.

Stu

die

s o

n

low

te

mp

era

ture

hyd

roly

sis

com

ple

ted

. Mo

del

ing

an

dva

lid

atio

n

of

hyd

roly

sis

com

ple

ted

.,Pri

limin

ary

stu

die

s o

nch

lori

ne

reco

very

in

itia

ted

.

1 (-

)

-

-

1 (-

)

-

-

Hig

h A

tom

Eff

icie

ncy

Pro

cess

es fo

r Bio

acti

ve a

nd

Sp

ecia

ltie

s

Ti-

TiO

2 N

ovel

an

d E

ner

gy

Effi

cien

t Syn

thes

is

29

4.1

DM

E fr

om

CO

an

d C

O2

4.2

Wa

ter

for

H2

pro

du

ctio

n v

ia s

ola

ren

erg

y ir

rad

iati

on

4.3

De

ve

lop

me

nt

of

cata

lyti

c am

mo

xid

at-

ion

te

chn

olo

gie

s a

tp

ilo

t sc

ale

fo

r th

esy

nth

esis

of

aro

mat

ica

nd

he

tero

aro

ma

tic

nit

rile

s

4.4

Dir

ect

hyd

roxy

lati

on

/o

xid

atio

n o

f b

enze

ne

and

its

der

ivat

ives

Pre

par

atio

n o

f M

EOH

deh

ydra

tio

nca

taly

sts

to g

et D

ME.

Act

ivit

y st

ud

ies:

Wat

er s

plit

tin

g w

ith

Ach

ieve

d m

ercu

ry v

apo

r la

mp

.

Scal

e u

p s

tud

ies

for

pre

par

atio

n o

fIN

H o

f p

har

mac

op

oe

ia g

rad

e i

nd

iffe

ren

t sc

ales

fro

m 5

0g

to

25

0g

bat

ch f

rom

4-c

yan

op

yrid

ine.

Stu

die

s o

n

de

velo

pm

en

t o

f an

effi

cien

t ca

taly

st f

or

pre

par

atio

n o

f3-

cyan

op

yrid

ine

fro

m 3

-pic

olin

e an

dto

gen

erat

e d

ata

for

tran

sfer

rin

g t

he

pro

cess

in

to c

om

mer

cial

pra

ctic

e.

Syn

thes

is a

nd

ch

arac

teri

zati

on

of

Ach

ieve

d m

eso

po

rou

s si

lica

(SBA

-15)

Alu

min

um

ph

osp

hat

e ca

taly

sts

wit

hA

I/P

=1

an

d A

lum

inu

m z

irco

niu

mp

ho

sph

ate

wit

h A

I/Z

r/P=

1:1:

2 w

ere

pre

par

ed b

y p

reci

pia

tio

n o

f m

ixtu

reo

f al

um

inu

m

and

/or

zirc

on

ium

nit

rate

an

d p

ho

sph

ate

pre

curs

or

(eit

he

r p

ho

sph

ori

c ac

id

or

dia

mm

on

ium

hyd

rog

en p

ho

sph

ate)

wit

h

NH

3

and

p

reci

pia

tio

n

of

alu

min

um

nit

rate

wit

h N

H3 f

ollo

wed

by

imp

reg

nat

ion

o

f p

ho

sph

ate

pre

curs

or

(eit

her

ph

osp

ho

ric

acid

and

d

iam

mo

niu

m

hyd

rog

en

ph

osp

hat

e).

Prep

arat

ion

of 5

0g a

nd

100

g b

atch

eso

f Iso

nic

oti

nam

ide

and

INH

has

bee

nst

and

ard

ized

get

tin

g 9

5% y

ield

of I

NH

wit

h h

igh

pu

rity

. Pre

par

atio

n o

f 250

glo

t o

f IN

H i

s in

pro

gre

ss t

o g

et t

he

des

ired

yie

ld a

nd

pu

rity

.

Pre

par

atio

n

of

cata

lyst

s an

dev

alu

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lter

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30

APPLIED RESEARCH :

Extraction and Isolation of Novel Synergistic

Anti-cancer Chemical Composition from Cedar

wood(US patent No. 6649650*).

Cedar wood(Cedrus deodara), a commercial source for

cedar wood oil is discovered as a source of a novel

synergistic lignan mixture of non volatile compounds

for anticancer activity. The nonvolatile fraction is

essentially found to be a mixture of three lignans, (-)-

matairesinol, (-)-nortrachelogenin and a dibenzylbuty-

rolactol lignan. These three compounds constitute

about 3-4% of the dried wood. Further when these

three compounds when tested over various cancer cell

lines, individually they are active only on one or two cell

lines. As mixture they are found to be active over a

wide range of cell lines and also more effective on each

of the cell lines. Based on this observation a process

has been developed to isolate the lignan mixture where

the mixture of the three lignans contribute to >96%

and present in a ratio of approximately 10:80:10. The

impurity profiling shows that these three compounds

are responsible for the biological activity. It is also found

that these three compounds are present in this ratio in

this plant. A process is developed for the extraction of

this lignan mixture from the plant which is commercially

viable and involves no chromatography. The LD50 value

is found to be >2200mg/Kg with signs of initial sedation.

It is licensed to M/S Indigene Pharmaceuticals Ltd., USA

and further developmental work is in progress.

New Natural Agent for Treatment of

Gastrointestinal Toxicity, Associated Symptoms

and Ulcers

The plants create unexpected and novel structures to

protect themselves from predator organism. By trial

and error, several plants and plant products are

identified as drugs. Natural Product drugs although are

highly effective and free from side effects have a

disadvantage with respect to short supply and often

have a complicated structure making their manufacture

difficult or sometimes impossible. Natural product

drugs have been a source of lead structure in drug

design and development. Semi synthetic analogues or

synthetic analogues closely related to the natural

product drug of lead are synthesized and screened to

improve their action. In the light of above descriptions,

isolation work at IICT afforded flavonoid derivatives

which are potent antiulcer agents increasing the gastric

pH, mucosal lining of stomach and related disorders

leading to the identification of plants belonging to the

genus Oroxylum, which contained in substantial yields

potent antiulcer flavonoids. Plants belonging to the

genus Oroxylum have been advocated in traditional

medical practice of India for several diseases. In folklore

medicine in India, the powdered stem bark is used to

treat dysentery, diarrhoea, sore throat, cough and bone

fractures (Kausik, P and Dhaman A. K, The medicinal

plants and crude drugs of India, 2000, 398). A new potent

broad spectrum antiulcer agent has been isolated which

displayed remarkable activity when tested in vivo

against different models. US, PCT and Indian Patents

have been filed.

NATURAL PRODUCTSNATURAL PRODUCTSNATURAL PRODUCTSNATURAL PRODUCTSNATURAL PRODUCTS

Accelerated Solvent Extractor

31

Single Molecule Antidiabetics

In the course of study IICT has identified several

traditional medicinal plants that bears substantial

amounts of α-glucosidase inhibitors coupled with

antioxidant activities. These activities together may

have superior preventive as well as therapeutic

importance than the existing modern α-glucosidase

inhibitors. Some of the well studied, potential and

published medicinal plants by IICT are given below:-

1). Veera taru ( Dichrostyches cinerea) is described in

Ayurvedic texts to tackle diabetes by multiple

mechanisms. IICT has isolated very potent α-

glucosidase inhibitor antioxidant molecule (-) mesquitol

in substantial yields from this medicinal plant based on

in-vitro studies and IICT also prepared several analogues

of this molecule. Some of the molecules have also

shown antihyperglycemic activity in animal

experimentation.

(Ref: Bioorganic Medicinal Chemistry Letters, 2003, 13,

2777-2780. USA 6,781,002., USA 0171674 A1, WO 054993

A1, WO 054995 A1)

2). Pippali (Piper longum) also contains very high yields

ofα-glucosidase inhibitors. Several molecules of various

class have been isolated and identified by IICT as α-

glucosidase inhibitors. IICT work was awarded first prize

in recent IUPAC international conference held in New

Delhi ( India ), Jan 26-31,2004. (Ref: USA 2004/0081711

AI, WO 041295 AI, MAPA,2004,26,194(Abstract No 2004-

02-0877)

3) Revandchini or Rhubarb (Rheum emiodi)is a

prescribed in several traditional preparation for various

diseases including diabetes from the rhizoma of this

medicinal herb. IICT has isolated several α-glucosidase

inhibitors coupled with anti oxidant activities in

substantial yields (Ref: Bioorganic Medicinal Chemistry

Letters, 2004, 14, 3841-3845)

4) Similarly, Tuvaraka (Hydnocarpus wightiara) has been

advocated in Ayurvedic classics as very potent

medicinal plant for diabetes. IICT isolated active

ingredient from this medicinal plant with high yields

and the α-glucosidase antioxidant principle shown

multiplies activities. (Ref: Phyto therapy Research

2005,19,277-281).

All these molecules offer exciting opportunity for their

development as antidiabetic therapeutics.

Candidates from CSIR CoordinatedProgramme

During the last six to seven years, IICT has developed

state-of-the art and world class facilities in ‘New

bioactive molecules from natural sources’ and

Standardization of Herbal Drugs. The facilities include

Personal Sepbox, an automatic chromatographic

purification system and Accelerated Solvent Extractor.

IICT has also entered into strategic alliance with M/S

Arya Vaidya Sala, Kottakal, Kerala for new bioactive

molecule research and process & product

standardization of certain classical antiarthritic

Ayurvedic Drugs. The later programme is supported

by DST under R&D pharmaceutical Section and will help

this Ayurvedic Industry in modernization and globalize

their products. The development of new bioactive

molecules from natural sources is carried out under

the umbrella of CSIR coordinated programme

‘Discovery, Development and Commercialization of New

Bioactives & Traditional Preparations’:

Under this programme IICT is exclusively dealing with

Ayurvedic Preparations from Arya Vaidya Sala, Kotttakal.

So far 72 Ayurvedic preparations were fractionated and

about 220 fractions were screened for 20 diseases. Based

on the In Vitro & In Vivo studies of these fractions 23

discovery groups have been formed under Drug

Discovery Programme. Some achievements of these

discovery groups are described below:

Natural Products

32

Antigastric Ulcer:

Originally AP-19 & AP-20 have shown antigastric ulcer

activity. Fractionation of these two preparations led to

loss of activity. Hence several herbal formulations have

been designed in collaboration with AVS. Out of these

75k and 76p have shown excellent antigastric ulcer

activity. 76p is taken up for further development

because of its superiority over allopathic drugs such as

omeprazole. CDRI has conducted the In vivo

experiments on five models 1. Cold Restraint induced

Ulcer test(CRU) 2. Aspirin Induced Ulcer 3. Histamine

Induced Ulcer 4. Pyloric ligation and 5. Ethanol Induced

Ulcer and IICB has conducted H. Pylori in vitro test. In all

these models 76p has shown equal or better activity.

76p is originally designed with eleven constituents. The

necessity of each and every constituent is now

established. From these studies efforts are then made

to minimize the number of constituents. 76p Batch-18

with the five constituents in equal proportions is found

to be equally effective. The final composition of 76p is

thus established. Preclinical toxicology studies are in

progress.

Memory Enhancing Activity:

AP-20 has originally shown Memory Enhancing

properties in In vivo models at CDRI. Fractionation led

to loss of activity. However, based on the literature

report isolation of active ingredient in the major plant

used in AP-20 is taken up. A single molecule is identified

which has shown Acetylcholine esterase inhibition in In

vitro model at CDRI. Racemic form of this compound

has been synthesized at IICT and found to be active in

Acetylcholine esterase model though the inhibition is

less. Efforts are then made to optimize this lead-

molecule. About 25 analogues were synthesized. All of

them were tested both in In vitro & In vivo models at

CDRI. Four compounds, AP-20am13, AP-20am14, AP-

20am15 and AP-20am16 were identified for further

development. The first two compounds have also

shown positive results for antidepressant activity at

ITRC in vitro model.

Leishmania:

Two single chemical entities, AP-38PL10 & AP-38PL15

are also reported to be strongly active by IICB. AP-

38PL15 and AP-38PL10 are tested in vivo at IICB and

found to be active.

New Bioactive Molecules(natural) discovered during

2003-05 are as below:

a. Single molecule antioxidants: No.

Free Radical Scavengers(DPPH): 21

Xanthine Oxidase Enzyme Inhibitors: 10

b. α-Glucosidase Inhibitors: 13

c. Hepatoprotective agent: 1

d. Anticancer compounds: 5

e. Acetylcholine esterase inhibitors: 2

f. Antibacterial Compounds: 8

g. Antifungal Compounds: 6

h. Leishmania 2

i. Antigastric ulcer 1

j. Antidiabetic 1

& analogues 2

————

Total: 72

————

These molecules are available for release to industry

on case to case basis.


33

BASIC RESEARCH BASIC RESEARCH BASIC RESEARCH BASIC RESEARCH BASIC RESEARCH

Designer Molecules from Sugar Amino Acidsand Other Scaffolds:

Cyclic and acyclic homooligomers of furanoidsugar amino acids: Cyclic homooligomers offuranoid sugar amino acids were synthesized,e.g, cyclic dimer (left) and trimer (right) of Gaa.Conformational analysis by NMR andconstrained MD studies revealed that all thecyclic products had symmetrical structures (J.Org. Chem. 2003, 68, 6257-63).

DRUGS & INTERMEDIATESDRUGS & INTERMEDIATESDRUGS & INTERMEDIATESDRUGS & INTERMEDIATESDRUGS & INTERMEDIATES

di-O-myristoylated Gaa into Leu-enkephalinestablished a well-defined β-turn structure inthe molecule (Tetrahedron Lett. 2004, 45, 5623-5627).

Conformational analysis of the linear tetramerof a glucose-derived furanoid sugar aminoacid:Gaa revealed that the fully protected tetramerhad a well-defined structure in CDCl

3 with

repeating b-turns (I), each involving a 10-membered ring structure with intramolecularhydrogen bonds between NH

i ® C=O

i-2. Its

deprotected versions showed aggregation inorganic solvents (II and III) with structuressimilar to that of the protected one(Tetrahedron Lett. 2004, 45, 3573-3577).

I II III

3,4-Di-O-acylated derivatives of furanoidsugar amino acids: 3,4-Di-O-acylatedderivatives of Gaa were synthesized as novelpeptide building blocks to study their effectson peptide conformation. Introduction of the

Conformational studies of peptides containingcis-3-hydroxy-D-proline: Conformationalanalysis of peptides containing cis-3-hydroxy-D-proline (D-cis-3-Hyp) by NMR studies revealedthat the 3-hydroxyl group in this amino acidplays a significant role in the overall three-dimensional structures of the peptidesexhibiting hydroxyl-assisted turn structures, inpolar solvents, similar to those found in theirfuranoid congeners (J. Org. Chem. 2004, 69,7399-7402).

Organic Synthesis and Synthesis of NaturalProducts

Total synthesis of (+)-crocacin A: Total synthesisof the potent antifungal and cytotoxic agent(+)-crocacin A has been carried out, wherecrucial (Z)-5,6-enoic amide moiety was built bystereoselective partial reduction of a skippeddiyne precursor. The diene, thus obtained, wastransformed into a silyl epoxide that wasregioselectively opened with an azide ion tofurnish an α-azido-β-hydroxyalkylsilaneintermediate. Peterson elimination of this b-hydroxysilane component in the final stepresulted in the formation of the (Z)-8,9-enamidemoiety of the molecule leading to a successfulcompletion of its first total synthesis.(Tetrahedron Lett. 2003, 44, 4989-4992).

34


Synthesis of δ-lctones: Radical-mediatedopening of a chiral trisubstituted epoxy alcoholusing cp

2TiCl furnished the “2-methyl-1,3-diol”

moiety with the desired stereochemistry whichled to a total synthesis of (3R,4S,5S,9S)-3,5,9-trihydroxy-4-methylundecanoic acid δ-lactone(I) (Tetrahedron Lett. 2004,45, 7637-7639) and 3,5-dihydroxy-2,4-dimethyl-n-heptanoic acidlactone (II) (Arkivoc 2005, iii, 170-178).

(Lys) (x 2.7). Inositol showed exceptionalproperty to solubilize silica (x 5). Designedpyridine- N oxides also solubilize silica(J.Chem.Sci., 2004,116,169-174).

Detailed SEM studies shown that the carrierimidazole significantly enhances the orderlydeposition of silica at bundle sheath sites in theleaf and that there is a direct correlationbetween the silicon deposited and the carrierefficiency. The SEM of the leaves of rice plantgrown with all the carriers have been securedand all of them show the expected silica uptake(biologia plantareem, 2005).

Acyl azides are valuable synthetic intermediatesin preparative organic chemistry. They undergofacile thermal rearrangement to isocyanatesfrom which urethanes, thiourethanes, amines,ureas, carbodiimides can be convenientlyprepared. A new method is developed for theone-pot oxidation of aldehydes to acyl azidesby using Dess-Martin periodinane and sodiumazide of 00C. (Tet Lett., 2003, 44, 3543-3545).Tegrahhedron LeH. 2003, 443543-3545.

A general and practical green chemistry routeto the Biginelli cyclocondensation reactionusing CeCl

3. 7H

2O as the catalyst (25% mol) is

described under three sets of reactionconditions ethanol, water and solvent – freeconditions (J.Org.Chem. 2003,68, 587-590).

Enantiomerically pure (S)- and (R)-naftopidil and(S)-atenolol was synthesized by utilizingJacobsen’s Hydrolytic Kinetic Resolutionmethod (Bioorg.Med.Chem.2005, 627-630;Chem. Lett. 2004, 1212-1213).

Environmentally benign selective method forthe regeneration of carbonyl compounds fromoximes and N,N-dimethylhydrazones inacetonitrile at ambient temperature of aqueousmedia has been carried in excellent yields underK

5C

oW

12O

40.3H

2O (0.01 equiv) catalysis (Synthesis

2003, 1883-1885).

Synthesis of highly substituted tetrahy-dropyrans: A propionate-derived polyketidebuilding block containing 2-methyl-1,3-diolmoiety was built by a Ti(III)-mediated ringopening reaction of a trisubstituted 2,3-epoxyalcohol precursor and used as a commonstarting material for the syntheses of highlysubstituted tetrahydropyrans, one of thembeing the C20-C28 fragment of cytotoxic naturalproducts, phorboxazoles (Tetrahedron 2003,59, 8613-8622).

Solubilization of silica: The ability of each ofthe coded a-amino acids to solubilize silica underambient conditions has been carried out bystandard analytical procedures to enable thedesign of peptides that could solubilize silica.Noteworthy enhancement was observed withimidazole (lm) (x 5), Histidine (His) (x 3), Glutamine(Gln) (x 3.5), Glutamic acid (Glu) (x 2.6) and Lysine

35

Glycochemistry: New disaccharides were synthesized fromthe chirons derived from easily and abundantly availablemonosac charides as chiral building blocks. Metalmediated reactions such as RCM protocol has been veryefficiently utilized to synthesize the cyclic pyran ringsystems, while, another metal mediated reaction such ascis-hydroxylation was later used to convert them intodeoxy disaccharides. Spiro saccharides also were preparedusing the RCM protocol on the sugar-derived chirons.Similarly, intramolecular nitrone cycloaddition protocolwas used for the construction of a variety of isoxazolidinesaccharides, having fused pyran and oxepene ring systems.

Synthesis of carbo-β-peptides and identificationof new secondary structures: A new area ofchemistry on carbo-b-peptides was initiated,wherein, C-linked carbo-b-amino acids (Caas) havingcarbohydrates as side chains were prepared andconverted into peptides. These were thoroughlyanalyzed by extensive NMR, MD and CD studies toidentify new helical structures, such as, right- andleft-handed 12/10- and 10/12-helices in thepeptides with alternating chirality and mixedpeptides, while a new helix namely 9/11-(11/9-)-helixwas for the first time identified in a/b-hybridpeptides. The cyclic peptides derived have shownthe presence of nanotubes through the TEMstudies.

Synthesis of bioactive natural products anddevelopment of new synthetic methods: Synthesisof anti-cancer active mocrotriolide class of naturalproducts, namely, macrosphelides (16-memberedlactones) A, C, E and F was achieved by chironapproach, using Yamaguchi macrolactonisa- tionmethod. Synthesis of verbalactone and attemptedsynthesis and structure determination of naturalproducts such as, feigrisolide, cladospilide and iso-cladospilide, acremonol and acremodiol resultedin non-natural products, while iso-avenaciolide, iso-canadensolide and iso-sporo- thriolide are theother non-natural products that have beensynthesized.

Trichlorotriazine and zirconium chloride wereutilized as Lewis acids for the protection/deprotection chemistry, besides being used for theefficient one-pot multicomponent couplingsreactions to prepare coumarins and otherglycoconjugates.

Stereoselective synthesis of L-733,060

Enantioselective synthesis of non-peptidic neurokininNK1 receptor antagonist L-733,060 is described usingring-closing metathesis as a key step, starting fromL-phenylglycine.

Tetrahedron Letters, 2003, 915-917

A short, simple and general approach for thesynthesis of (3S,4S)-3-methoxy-4-methylamino pyrrolidine and (3S,4R)-3-methoxy-4-methyl amino pyrrolidine

A general and efficient stereoselective approach for thesynthesis of (3S,4S) and (3S,4R)-3-methoxy-4-methylamino pyrrolidines, a part of the structure of AG-7352, a naphthyridine antitumor agent and quinolineantibacterial compounds has been described.

Tetrahedron Letters 2003, 5687-5689

An efficient synthesis of protected( 2 R , 3 R , 4 S ) - 4 , 7 - d i a m i n o - 2 , 3 -dihydroxyheptanoic acid, a constituent ofcallipeltins A and D

Drugs & Intermediates

NH

O

CF3

CF3

L-733,060

N

N S

NN

O

MeHN

MeO

COOH

N N

O

MeO

COOH

2HN

F

FMeHN

36


Stereoselective synthesis of (-)-cytoxazoneand (+)-5-epi-Cytoxazone

Stereoselective synthesis of (-)-cytoxazone anImmuno modulator and its epimer (+)-5-epi-Cytoxazone has been achieved from 4-hydroxyphenyl glycine. They also found to haveantibacterial activity.

Synthetic Communications, 2003, 2907

A versatile and efficient synthesis of (2S)-2-(hydroxymethyl)-N-Boc-2,3-dihydro-4-pyridone

A versatile and efficient method for the preparationof (2S)-2-(hydroxymethyl)-N-Boc-2,3-dihydro-4-pyridone from L-(-)-phenylalanine utilising thearomatic system as a masked â-keto aldehyde wasdeveloped. The key step in the sequence is anintramolecular cyclisation to give 2,3-dihydropyridin-4-ones

Tetrahedron Letters: 2003, 4261-4263

Stereoselective synthesis of 1,4-dideoxy-1,4-imino-L-allitol and formal synthesis of(2S,3R,4S)-3,4-dihydroxyproline

A stereoselective synthesis of 1,4-dideoxy-1,4-imino--allitol and formal synthesis of (2S,3R,4S)-3,4-dihydroxyproline was achieved via the addition ofvinylmagnesium bromide to the benzyliminederived from (R)-2,3-O-isopropylideneglyceraldehyde followed by N-allylation, ring-closing metathesis (RCM), and dihydroxylation.


A shortest stereoselective syntheses ofChloramphenicol and Thiamphenicol:

A common strategy for the synthesis of (-)-chloramphenicol and (+)- thiamphenicol isdescribed These antibiotics have been synthesizedfrom commercially available 4-nitrobenzaldehydeand 4-(methylthio)benzaldehyde in three and foursteps, respectively.

Tetrahedron:Asymmetry 2004, 1279-1283

An efficient and stereoselective synthesis of protected(2R,3R,4S)-4,7-diamino-2,3-dihydroxyheptanoic acid, aconstituent of the depsipeptides, callipeltins A and D,from L-ribose is described.

Tetrahedron Letters, 2003, 5645 Stereoselective synthesis of (-)- and (+)-pentenomycins using RCM

An efficient synthesis of enantiopure (-)- and (+)-pentenomycins are described by reductive iodoelimination and ring-closing metathesis (RCM), asthe key steps. The first synthesis of the unnatural(+)-isomer is described.

Tetrahedron Letters, 2003, 5103

NH

NH

NH

2HN

NH

OH

OHO

HN

O

OH

O

O

NH2

HN

OO

O

NH

O

MeN O

MeO

OH

NH

O

NMe

CONH2

O

NHO

HN

OH

NH

NH

NH2

Callipeltin A

NBoc

OH

O

NHBoc

OH3 steps

OMe

H

HO

O

O

45

NH

H

OMe

H

HO

O

O

45

NH

H

O

OH

OH

OH

O

OH

OH

OHD-Mannose D-Ribose

(-)-Pentenomycin (+)-Pentenomycin

NH

HO OH

HO

HO

NH

HO OH

COOHandD-Mannitol

37

Chiron approach to (1R,2R,5S,7R)-2-hydroxy-exo-brevicomin

Chiron approach to the synthesis of (1R, 2R, 5S, 7R)-2-hydroxy-exo--brevicomin 1, a component of thevolatiles obtained from male mountain pinebeetles, Dendroctonus ponderosae has beenachieved. Our synthesis started with commerciallyavailable D-Mannitol and involved Wittigoleifination, acid catalysed one pot hydrogenationand internal acetalization as key steps.


Stereoselective synthesis of (3R,4S)-3-methoxy - 4-methylaminopyrrolidine

An efficient stereoselective approach for thesynthesis of (3R,4S)-3-methoxy-4 methylamino

Stereoselective synthesis of (-)-pestalotin

The asymmetric synthesis of (-)-pestalotin isdescribed using OsO

4-catalyzed asymmetric

dihydroxylation and utilization of substitutedaromatic system as masked â-ketoester as the keysteps in the reaction sequence.

ARKIVOC, 2005, 74-82

Asymmetric syntheses of (1R, 1’R, 5’R, 7’R)and (1S, 1’R, 5’R, 7’R)-1- hydroxy-exo-brevicomin and a formal synthesis of (+)-exo-brevicomin:

Asymmetric syntheses of (1R, 1’R, 5’R, 7’R) and (1S,1’R, 5’R, 7’R)-1-hydroxy-exo-brevicomins 1 and 2,volatiles of the male mountain pine beetle and aformal synthesis of (+)-exo-brevicomin 3, acomponent of the attracting pheromone systemof several bark beetles has been achieved. The keysteps are Birch reduction of commercially availablea-picoline, selective Wittig olefination and Sharplessasymmetric dihydroxylation.


pyrrolidine, a part of the structure of quinolineantibacterial compound (1a) and the naphthyridineantitumour agent (1b) has been described.


The first stereoselective synthesis of naturalanhydrophytosphingosine Pachastrissamine (Jaspine B):

The synthesis of the natural anhydrophytosphingosine pachastrissamine (jaspine B) 1a fromGarner_s aldehyde is described.



O

O

OH

O

O

OH

O

O

OH

O

OBnO

O H2, Pd/C

aq HCL(cat)MeOH

D-Mannitol

(1R, 2R, 5S, 7R)-2-hydroxy-exo- brevicomin

N

O

O

O

O

OH

O

O

OH

5 steps 7 steps

+

(+)-exo-brevicomin(1R, 1'R, 5'R, 7'R) and (1S, 1'R, 5'R, 7'R)-1-hydroxy-exo-brevicomins

2ON

OH

OH

NHCOCHCl2MeS2O

OH

OH

NHCOCHCl2

(-)-Chloramphenicol (+)-Thiamphenicol

O O

O

H

NH

MeO NHMe

(R,S)-2

.2HCl

O NBOC

O

H

O O

RHN OR

C14H29

RHN OR

C14H29

+

9 steps

1a R=H2a R=Ac

1b R=H2b R=Ac

O

O

OEt

OH

OH

OMe

OH

OMe

O

(-)-Pestalotin

38


A short, stereoselective and commonapproach for the synthesis of 4,5-disubstituted δ-lactones simplactone B and its C-5analogue:

A short, stereoselective, and a common approachfor the synthesis of 4,5-disubstituted d-lactonessimplactone B and its analogue using Evansprotocol is described.

Bioorganic Medicinal Chemistry letters, 2005, 2085-2086

A new approach to (+)-anisomycin

An efficient approach to optically pure (+)–deacetylanisomycin 2a and a formal synthesis of(+)-anisomycin 2 have been achieved throughsimple and good yielding reactions, starting from1,2:3,4:5,6-tri-O-isopropylidene-D-mannitol 3.Grignard reaction and intramolecular cyclisationreactions are key steps in our strategy.

Tetrahedron: Asymmetry: Article in press 2005

A chiron approach to (1R,2R,5S,7S)-2-hydroxy-endo-brevicomin:

A chiron approach for the synthesis of (1R,2R,5S,7S)-2-hydroxy-endo-brevicomin 1, a component of thevolatiles obtained from male mountain pinebeetles, Dendroctonus ponderosae has been

Stereoselective synthesis of (2S,7S)-7-(4-phenoxymethyl)-2-(1-N-hydroxyureidyl-3-butyn-4-yl)oxepane:

We have achieved a short, efficient stereoselectivesynthesis of 7-membered oxepane derivatives withpotential against asthma. Highlights of oursynthetic strategy are regioselective oxidation of ahydroxyl group and efficient ring closure of an openchain aldehyde to a 2-benzenesulfonyl oxepanederivative with PhSO

2H. Surprisingly the cis-isomer

showed better activity than the trans-isomer.

Tetrahedron: Asymmetry 2005, 935-939

Stereoselective synthesis of (-)-gabosine C:

An efficient synthesis of (-)-gabosine C and a formalsynthesis of (-)-COTC 4 are described using theNozaki– Hiyama–Kishi (NHK) reaction and RCM asthe key steps.


achieved. Our synthesis started with commerciallyavailable D-ribose and involves a Wittig olefination,an acid catalyzed one-pot hydrogenation and theinternal acetalization as key steps.

Tetrahedron: Asymmetry 2005, 1611-1614

O

N

O

NH2

OH

OF

H H

(2S,7S)-7-(4-phenoxymethyl)-2-(1-N-hydroxyureidyl-3-butyn-4-yl)oxepane

O

OH

H3C

O O

OH

C14H29

O

O NH

Bn

O

Simplactone B 2 C-5 analogue ofsimplactone 3

HO

O

OH

OH

OH

O

O O

HO

MOMO HO

O O

OTHP

(-)-gabosine C

O

O

OH

H

D-Ribose

7 steps

(1R,2R,5S,7S)-2-hydroxy-endo-brevicomin

NR'

RO OHMeO

D-(+)-Mannitol

R = Ac, R' = H (+)-anisomycinR = R' = H (+)-deacetylanisomycin

39

Asthma and allergic disorders mitigation mission-Synthesis of PDE-4 inhibitors: Asthma is a complex,multifactorial disease characterized by reversible airwayobstruction, airway-inflammation, non-specific airwayhyperactivity with a variety of pharmacological andenvironmental challenges. Cyclic 3’, 5’-adenosinemonophosphate (cAMP) and cyclic 3’, 5’-guanocinemonophosphate (cGMP), are second messengers thatare involved in a wide range of physiological processes.It has been established that PDE-4 enzyme is responsiblefor the breakdown of cAMP/cGMP in many types ofinflammatory cells and generate 5’-AMP and 5’-GMPrespectively, as inactive products. Thus, the obviousbiochemical consequence of cAMP specific PDE-4inhibition is the increase in the intra-cellular level of cAMP.Hence, design and synthesis of PDE-4 inhibitors wasundertaken for the development of potential drugs for

APPLIED RESEARCHAPPLIED RESEARCHAPPLIED RESEARCHAPPLIED RESEARCHAPPLIED RESEARCHDST-DABUR-IICT collaborative project on

development of peptide based anti-cancercompounds : In this project, several peptidomimeticanalogs of the VIP receptor binding inhibitor Leu-Met-Tyr-Pro-Thr-Tyr-Leu-Lys were prepared by insertingfuranoid sugar amino acids into the molecule at variousplaces. The resulting analogs were tested for their anti-cancer activities in vitro, following the standard MTTassay on a panel of human cancer cell lines. One of thepotent analogs was tested in vivo for tumor regressionon primary colon tumor xenografted nude mice, whichshowed that the percentage inhibition of tumor growthcaused by that particular analog as compared tocontrols on day 21 was 57%. The experimental resultssuggest that many of these analogs show eitherretention or enhancement of biological activity(Tetrahedron 2004, 60, 8329-8339).

the treatment of asthma. A large number of NCEs weresynthesized and subjected to testing. 30 NCEs haveshown promising PDE activity, which are under furtherinvestigation for the lead generation and leadoptimization.

New route identification for fragranc e chemicals(Givaudan, Switzerland): A collaborative project wasinitiated between IICT and Givaudan, Switzerland, forthe identification of new synthetic routes for twofragrance molecules and developing them intoeconomically viable process routes. Innovative chemicalroutes for the Givaudan molecules are alreadyestablished. Simple and high yielding conditions wereestablished for reducing double bond, while the yieldsin the acid catalysed cyclisation were improved from6% to 40%. Further work is in good progress tocomplete the synthesis.

Synthesis of combinatorial libraries for theevaluation as agrochemicals (Dupont, USA): Fourprojects were undertaken with DuPont, USA, for thesynthesis of libraries of NCEs to evaluate them asagrochemicals. New chemistry was developed forpreparing the scaffolds and the thus made scaffoldswere efficiently converted into NCEs, wherein severalmodifications were brought about in chemical reactions.

BIOTRANSFORMATIONS:

IICT has been actively involved in biotransformations/biotechnology with a view to develop greener and saferprocesses/technologies catalyzed by enzymes. Incontinuation of our efforts towards the synthesis ofbiologically important compounds, new and simplemethodologies have been developed for the synthesissome drugs, drug intermediates and for commerciallyimportant chiral compounds.

Enantiomerically pure ß-hydroxy nitriles

Optically active ß-hydroxy nitriles are usefulintermediates in the preparation of functionalized chiralsynthons and have wide applications in the preparationof a large number of natural products, antibiotics,serotonin reuptake inhibitors (fluoxetine, duloxetineetc.) and chiral auxiliaries. Various methodologies havebeen reported in literature for the preparation of thesenitriles. Nevertheless, there is a scope for preparingthese optically active compounds by employingenzymatic approaches. In this context, different lipases


Superimposition of the H-bonded regions of the VIP

antagonist (blue) and its analogs (other colors)

40

O

S

NHCH3

(S)-Duloxetine

US patent Appl. No. 10/393,406Tetrahedron Lett. 2003, 44, 4783


Amino alcohols

Optically active secondary amino alcohols areimportant intermediates for asymmetric synthesis ofbiologically active substances such as adrenergicagents, antihelmintics, antidepressants, â-blockers andantiarrhythmic agents. A new one-pot enzymaticresolution method has been developed which providesan alternate short synthetic route for the preparationof enantiopure propranolol and sotalol.

US Patent Appl. No. 11/022,275Tetrahedron: Asymm, 2005, 16, 1485

S-Levamisole

Bioorg. Med. Chem. Lett. 2005, 15, 613

Tetrahedron: Asymm. 2004, 15, 3939

have been investigated for the kinetic resolution of 3-aryl-3-hydroxypropane nitriles by transesterificationprocess. The resolved hydroxy nitriles have been utilizedfor the preparation of fluoxetine and duloxetine. Thisapproach has been extended for chemoenzymaticsynthesis of different â-blockers and also GABOB andcartinine. Further, this methodology has also beenutilized for the preparation of optically pure â-hydroxylnitriles and their application towards the synthesis oflevamisole.

US patent Appl. No. 10/393,406Tetrahedron Lett. 2003, 44, 4783US patent Appl. No. 10/393,406Tetrahedron Lett. 2003, 44,4783

Bioorg. Med. Chem. Lett. 2004, 14,4581

Azido alcohols

Azidoalcohols are commercially useful intermediatesfor different pharmaceutically important compounds.A simple and highly efficient methodology has beendeveloped for the preparation of optically active â-azidoalcohols, which have been utilized towards thepreparation of biologically active amino alcohols suchas tembamide, aegeline and denopamine.

HO OCOR

OCOR

HO OCOR

OCOR

R= C15H31

HN

O

OH

MeO

HN

O

OH

MeO

HN

OH

MeO

OCH3

OCH3

Tembamide Aegeline Denopamine

N

N

S

COOHH2N

OHCOOHN

OH

Cl-

(R) - GABOB Carnitine hydrochloride

+

OHN

OH

(S)- Propranolol

HN

OH

NH

SMe

O

O

(S)-Sotalol

NHCH 3

O

F3C

(R)-Fluoxetine

PCT Appl. No. WO 02/057475

O

S

NHCH 3

(S)-Duloxetine

US patent Appl. No. 10/393,406Tetrahedron Lett. 2003, 44, 4783

(S)-and (R)-O-(4-methoxyphenyl)-glycidol

Tetrahedron: Asymm. 2005, 16, 1485

41

Indian Patent Applied.

A large number of organisms have been screened forthis transformation and some of the positive strainsare being investigated for their practical utility in thistype of transformation. Some microbes belonging toCandida, Pichia, Rhodotorula, and Gordonia sp. have beeninvestigated for the production of brassylic acid fromtridecane and found them to be positive.

Pre-Biotech Incubator Process Generator(PBG)

This centre, which is in the process of completion, will

house facilities for carrying out biotechnology based

research. This will allow fermentation and enzymatic

reactions to be carried out at bench scale. It also

includes auxiliary facilities for cell culture, media

preparation and related down stream facilities.

Design and Synthesis of Anticancer Agents:Molecular Recognition of DNA

In recent years there has been considerable interest in

the design and development of DNA interactive ligands

that are capable of binding the DNA in a sequence

selective manner. These gene-targeting compounds

have potential in the therapy of genetic based diseases

including some cancers, diagnostics and validation of

DNA sequences. Naturally occurring pyrrolo[2,1-

c][1,4]benzodiazeipnes (PBDs) have attracted the

attention of many researchers largely because of the

potent anticancer activity exhibited in most of the

compounds with this ring system. As a part of

continuing research on design and synthesis of new

anticancer agents, a number of hybrid molecules

containing PBD ring system have been synthesized to

improve upon the binding ability and sequence

selectivity. During this process some new and efficient

synthetic strategies including the solid phase synthesis

have also been developed.

Some of the notable findings of this research activity

include the linkage of DNA interactive moieties like

naphthalimides and alkyl amino compounds, pyrene,

acridone, fluoro aryl substituted pyrimidines and

benzimidazoles through different type of spacers. A

number of compounds from the new class of hybrids

have promising in vitro anticancer activity with efficient

DNA binding ability and base pair sequence selectivity.

Few new molecules are undergoing in vivo studies for

anticancer activity.

Intermediate for antitumour compound AG7352

Tetrahedron Lett. 2004, 45, 8057

Compound AG 7352 claimed to possess equal orsuperior antitumor activity to those of cisplatin andetoposide against human breast, ovarian and coloncancers implanted in nude mice. The stereo chemistryof 3-methoxy-4-methyl aminopyrrolidine group at theC-1 position of AG-7352 is responsible for its antitumoractivity. An efficient chemoenzymatic method has beendeveloped for the synthesis of 3-methoxy-4-methylamino pyrrolidine in high enantioselectivity.

Microbial oxidation of long chain alkanesThe terminal oxidation of long chain alkanes such asdodecane and tridecane (petrochemical feed stocks)provides the industrially important dicarboxylic acids.Microbial oxidation of such alkanes is a potential andversatile method.


COOHHOOC

Brassylic acid

N N

SN

NMeHN

CO2H

AG-7352

MeO

O

NR

1

MeO NHR

(S,S)

R=Me, R1=H

R= R1=Boc

42

Design and Synthesis of AntitubercularAgents

The research in drug resistant tuberculosis hasgenerated a renewal of interest in a strategic search for

Bioorg. Med. Chem. Lett. 2005, 15, 1927-1929

Bioorg. Med. Chem. Lett. 2005, 15, 1923-1926

IP Licensing

IICT/CSIR entered into an exclusive agreement withM/s. Ind US Pharmaceuticals, USA, for licensing of USpatents [US 6884799, US 6800622, US 6362331 & US6683073 and US patent application US2004/0192678Aof Dr. Ahmed Kamal, et al] with respect to pharma-ceuticals, drug discovery and drug development of newmolecule entity.

Contract Value: US $ 1,00,000 (including patent costs)followed by milestone payments at different stages.

prototype leads. Many studies are being attempted todevelop new anti-tubercular compounds to resolvesome of the problems with the currently availableantitubercular drugs. In this connection a project wasinitiated in this laboratory to design and synthesizestructurally modified new molecules based on theexisting leads. In this effort a number of compoundssuch as phthalimido, naphthalimido linked phenazines,thiolactones, benzothiadiazines, coumarines andquinalones have been synthesized and evaluated fortheir antitubercular activity. Amongst these,benzothiadiazine based scaffolds have exhibitedpromising antimycobacterial activity.


N

N

O

H

H3CO

OO (CH2)n

n = 3-5R = H, N-methylpiperazine

R

HN

NR

N

N

O

H

H3CO

O

O

(CH2)nN

H

n = 3, 4

N

N

O

H

H3CO

O

O

(CH2)nN

H

n = 3, 4

N

N

O

HN

N

O

H HO

OCH3

O

H3CO

n = 1, 3

n

N

N

HN

NN N Cl N

O

O

( )2 ( )n

Cl

S

O

O

SOCH3

O

n

CH3

H3C

N

N

O

H

H3CO

O

NH

N

OO

O

N

O

O

43

Esfenvalerate

IICT has developed a technology for manufacture ofchiral esfenvalerate an insecticide with export potentialand Indian market. The introduction of single isomerpesticides has become a requirement to achieve higheractivity, lower requirement per hectar and minimizationof residual toxicity. A bench scale process wasdeveloped and transferred to Virchow LaboratoriesLtd., Hyderabad and Bharat Rasayan Ld., New Delhi.

The significant achievement in the process is kineticcontrol / dynamic resolution technique that gives highchiral purity product. This claim has been applied forgrant of patent in PCT, India.

Indoxacarb

Process for manufacture of Indoxacarb is nearingcompletion. The project was sponsored by a consortiumof Pesticide Formulator and Manufacturers Associationof India (PFMAI). The technology will be transferred soon.

Bio-Pesticides from Neem

Market need based technology upgraded process toprepre high azadirachtin was developed on the benchscale and transferred to Mythri Agro Industries, Kerala.The export grade azadirachtin required stringentspecification requirements such as 40% ± 5 azadirachtincontent (assay by HPLC & PTLC), characterization of otherconstituents present above 0.2%, stability data ofseveral export grades of azadirachtin on storage; toxicitydata for application in health care products preparation;variation of azadirachtin content in various varieties ofneem seeds and kernels procured at different agroclimatic conditions. Much of the critical data requiredfor other than agrochemical use was developed at IICTand the work has already been patented in the US, EP,Canada, Japan and Australia.

AGROCHEMICALSAGROCHEMICALSAGROCHEMICALSAGROCHEMICALSAGROCHEMICALS

Director, IICT (left) is seen with the project team of the processfor biopesticide formulation from neem seed/kernel

Field Pheromone Lures developed by IICT

Bio-pesticides technologies developed on bench scaleare for annona and karanja and transferred to SriBiotech, Hyderabad. These technologies meet due tomeeting of specification requirements for export.

PHEROMONE CHEMICALSInsect pheromones with their unique mode of actionoffer an excellent potential for monitoring and controlof insect pests and are considered as an importantcomponent in Integrated pest managementprogrammes. Insect pheromones are highly specific inaction, low toxic to human, easily biodegradable andleave negligible or zero residues in the environment.Continuous research on Isolation and identification ofpheromone systems of pests having economicimportance pertaining to India and synthesis ofcommercially significant pheromone components intheir purest form is essential for practicalimplementation of technology. In this direction, thepheromone group at IICT as a package programme isactively engaged in all aspects of pheromonetechnology right from isolation, identification, synthesisof pheromone components, dispenser developmentand finally the field application.

Isolation and Identification of PheromoneComponents: Pheromone systems of ten insectspecies of Indian origin have been identified duringthe previous years. Currently work on isolation andidentification of pheromone systems ofpomegranate fruit pests Eucidoma maternal/fullonia and Deudorix isocrates is under progress.

Synthesis of Pheromone Components:Pheromone components of the followingcommercially important crop pests weresynthesized at 25 gm batch size and thetechnologies are ready for transfer to industry:

44

Insect Pheromone components Crop

1. Chilo sacchariphagous indicus Z13

Octadecenyl acetate (7) Sugarcane

(Sugarcane inter node borer ) Z13

Octadecenol (1 )

2. Scirpophaga excerptalis E11

Hexadecenal (70) Sugarcane

(Top shoot borer) Z11

Hexadenol (30)

3. Chilo infesculatus Z11

Hexadenol Sugarcane

(Early shoot borer)

4. Plutella xylostella Z11

Hexadecenyl acetate (10) Cabbage &

(diamond back moth) Z11

Hexadecenal (10 ) Cauliflower

Z11

Hexadecenol (0.1)

5. Leucinodes orbonalis E11

Hexadecenyl acetate (10) Brinjal

(Brinjal fruit & Shoot borer) E11

Hexadecenol (1)

6. Helicoverpa armigera Z11

Hexadecenal (97) Cotton

(American bollworm) Z9 Hexadecenal (3)

7. Pectinophora gossypiella Z7,Z

11 – Hexadecadienyl acetate (50) Cotton

(Pink bollworm) Z7,E

11 Hexadecadienyl acetate (50)

8. Earias vitella E10

,E12

Hexadecadienal (10) Cotton

(Spiny bollworm) Z11

Ooctadecenal (2)

Z11

Hexadecenal (2)

9. Aproaerema modicella E7 Decadienyl acetate (20) Groundnut

(Groundnut leafminer) Z7 Decadienyl acetate (100)

Z7

Decenyl acetate (14)

10 Musca domestica Z9 Tricosene Domestic

(Common housefly)

Dispenser Development: Identification of suitable

dispenser is important for the successful release rates

of pheromone blend over a period of time during the

crop cycle. Trap catch data, release rates and persistence

of pheromone blend in the dispenser are taken as

parameters for the selection of proper dispenser for

particular insect pest . Solvent pretreatment and lure

impregnation methods for each dispenser types are

also standardized while identifying the suitable

dispenser. Anti oxidant was always added to the lures

in order to protect the pheromone components from

light, temperature etc. The following is the summary/

achievements of the work carried out during 2003-2005


45

S.No. Insect Dispenser Type

1. Groundnut leafminer Plasticvial

2. Pink bollworm Plastic vial

3. American bollworm Yellow/white rubber septa

4. Sugarcane internode borer Black rubber septa

5. Spiny bollworm Green rubber septa

6. Brinjal fruit and shoot borer Rubber septa

7. Diamond back moth Rubber septa

Field Evaluation and Popularization: Field evaluation of synthesized components is the crucial and most importantstep to bring the developed technology to the end user for the benefit of society. This challenge was taken up atvillage level basis in farmers fields with the help of various Agricultural universities, NGO groups and ICAR institutes.Laboratory synthesized pheromone lures were placed in cost effective trapping devices/traps designed (particularlyfor groundnut leaf miner) and prepared with locally available raw material. Different trap types were designeddepending upon the size and flight activity of particular insect pest. Weekly trap catch data was recorded in differenttrap type to select the best suitable trap for each targeted insect The various field experiments conducted atdifferent locations are summarized below.

S.No. Insect Crop Location Mode of Control CollaboratingInstitute/ NGO

1.

2.

3.

4.

5.

Yellow

Stemborer

Gram Pod

Borer

Groundnut

leaf miner

Sugarcane

internode

borer

Spiny boll

worm

Rice

Cotton

Groundnut

Sugarcane

Cotton

West Godavari (A.P.)

Nizamabad (A.P.)

Warangal& Nizamabad

(A.P.)

Dhule (Maharashtra)

Mahboobnagar and Nalgonda

(A.P.)

Dindivanam (TN)

Coimbatore (TN)

Dhule (Maharashtra)

Mahaboob nagar (A.P.)

Monitoring

Mass

trapping

Monitoring

Monitoring

and Mating

Disruption

Monitoring

and Mass

trapping

- do -

Monitoring

and Mass

trapping

Monitoring

& Mass

trapping

- do -

Directorate of

Rice Research

(DRR)

PEACE (NGO)

MPKV Dhule

IICT SDDPA

and KVK

(NGO)

NRCG,

Junagadh

Rajashree

Chemicals Pvt.

Ltd.

MPKV, Dhule

IICT

PPPPPheromone Chemicalsheromone Chemicalsheromone Chemicalsheromone Chemicalsheromone Chemicals

Agrochemicals

46

The feed back from the farmers was encouraging and

the farmers during the farmers meet were found eager

and fully co-operative to adopt pheromone technology

for the pest management.

Quality Assessment : Successful application of

pheromone technology in IPM depends on the purity

and specific ratio of each of the pheromone

component of the specific blend. Slight variation in the

purity or the blend ratio may influence trap catches in

the field. Hence, a careful check / quality assurance of

the product is needed at the laboratory level, before

being brought in to the market. Laboratory evaluation

for the presence of pheromone components by

analytical methods before and after field exposure of

the lure is important to ascertain the efficacy

persistence of pheromone formulations. Sophisticated

analytical techniques like Gas Chromatograph (GC) and

GC-linked Mass Spectrometer (GC- MS) are employed

for the purpose of analysis. Structure confirmation and

purity profiles of the synthetic intermediates of the

process technology are done by standard

spectroscopic methods (NMR, IR, MS and GC). This also

helps in avoiding the usage of spurious lures.

Pheromone group at IICT regularly provides its service

to Department of Agriculture (Govt. of A.P.) and other

Private entrepreneurs to attain quality assurance

certification for the different pheromone lures.

International Collaboration : Pheromone group has

established several collaborative linkages withinternational research institutes and universities. TNOthe Netherlands, was the first collaborative institutewhich helped in establishing the requiredelectrophysiological equipment and the expertise in thefield of pheromone research. Several successivelinkages with Department of Biological OrganicChemistry IIQAB/ CSIC Spain under DST programmeand University of Keele U.K. under DFID highereducation links also helped for successful transfer ofexpertise. During this period the CID-CSIC, Barcelona,Spain research programme with the support of Ministryof Spain and University of Keele, UK programme undersponsorship of British Council are activelyimplemented.

Training Programmes Organized: Training in

pheromone lure preparation and impregnationtechniques is provided to enthusiastic personnel fromGovernment (NCIPM, Delhi) Non governmentorganizations and industry (Rajashree Sugars Pvt. Ltd.)on payment and non payment basis in order topopularize pheromone technology.

6.

7.

8.

Brinjal

shootand

fruit borer

Diamond

back moth

Pink

bollworm

Brinjal

Cabbage

Cotton

Bhuvaneswar (Orissa)

Rangareddy (A.P.)

Rangareddy (A.P.)

Dhule (Maharashtra)

Rangareddy &

Mahaboob nagar (A.P.)

Monitoring

& Mass

trapping

- do -

Monitoring

&Mass

trapping

Monitoring

& Mass

trapping

- do-

IIHR

IICT

IICT

MPKV

IICT


47

Value upgradation and Byproduct Utility for n-Butylbenzene

SPECIALITY AND FINE CHEMICALSSPECIALITY AND FINE CHEMICALSSPECIALITY AND FINE CHEMICALSSPECIALITY AND FINE CHEMICALSSPECIALITY AND FINE CHEMICALS

application for resolution of 1-arylalkymaines in 74-99%

enantiomeric purity has been demonstrated. This work

finds application in manufacture of single isomer drugs

and pesticides by diastereomeric crystallization

method.

New Photolabile Molecules

Photolabile protecting group find application in biology

for study of biological processes through labeling. The

study makes use of triggering the molecule with light

and track the product with detection at –ë 350 nm and

–ë 400 nm. A new efficient ‘Bis(4,5-dimethtoxy-2-

nitrophenyl) ethylene glycol’ protecting group has been

synthesized and shown its potential for biological

application.

Strategic Materials for Manufacture of

Photoresists

Photoresists are used in manufacture of

microelectronics required for developing strategically

important instruments. Such materials are not available

in public domain for use. Hence, IICT has taken up this

activity and prepared ‘photo activating compounds

(PAC)’ and filed several patents world over. This work is

done in collaboration with several other institutes (NCL,

Pune, Defence Departments, etc.) to formulate then

before they are found suitable for end use.

Design and Development of New Chiral

Resolving Agents: Phthalate Esters of Sugar-

Derivatives

Several acidic chiral resolving agents derived from

carbohydrate templates have been designed. Their

n-Butylbenzene is a byproduct obtained in the

manufacture isobutylbenzene, the key raw material for

anti-inflammatory drug Ibuprofen. About 250 MT /

annum of n-butylbenzene is obtained in the process.

IICT has developed a process to manufacture six

products namely Butyrophenone, 1-phenyl n-

butylamine (recemic) (R)1-phenyl n-butylamine (1), (S)1-

phenylbutylamine (2), 4-n-Butylaniline (3)and 2-n-

butylaniline (4), will be available in commercial

quantities. The chiral versions of the same is likely to

find market in drug discovery research as a resolving

agent and development of new chiral scaffolds.

(3)(3)(3)(3)(3)

48

Fluoroquinolones- Antibacterial agents

APPLIED RESEARCH

2,2,2-Trifluoroethanol (TFE)

TFE is an important fluoroorganic compound used asheat absorption liquid in pumps, an intermediate foranaesthetic desflurane etc. IICT has entered into anagreement with M/s. Navin Fluorine Industries, Surat,on non-exclusive basis to develop a catalytic processfor TFE starting from HCFC-133a. The IICT hassuccessfully developed and demonstrated a lab scaleprocess on 250g scale and submitted demonstrationreport to M/s. Navin Fluorine. The project is underimplementation by the firm.

Heptafluoropropane (FM-200)

Heptafluoropropane (HFP) is a hydrofluoro carbon, hasbeen accepted world over for many applications due toits zero ODP, low GWP and toxicity and is one of the bestchemical substitutes for halons. HFP has wideapplications where halon-1301 was used in the past.

IICT has entered into an agreement with M/s. Centre forExplosive and Environment Safety (DRDO) Delhi forDevelopment of process for HFP on non-exclusive basis.An optimized process is developed on bench scale andplanned to demonstrate during October-November2005. CFEES is looking for an industrial partner forcommercialization of process.

1,1,1-Trifluoro,2,2-dichloroethane (HCFC-123)

It is a hydrofluorochlorocarbon aimed at using as anintermediate range substitute for banned chlorofluoroarbons. HCFC-123 is used as refrigerant foam blowing

FLUOROORGANICSFLUOROORGANICSFLUOROORGANICSFLUOROORGANICSFLUOROORGANICS

agent. The process for HCFC-123 is developed atlaboratory scale and ready for release. Upscaling ofprocess on pilot plant scale may be takenup onsponsorship bais.

HFC-134a

HFC-134a pilot plant studies have been completedsatisfactorily. A commercially acceptable quality HFC-134a product (99.8%) is produced. All the technicalinformation is compiled and submitted demonstrationreport.

BASIC RESEARCH

The synthesis of fluorinated heterocyclic molecules ofbiological importance were planned and executedunder basic research programme. The contributiontowards basic research resulted in good number ofpublications and patents. Some of them are highlightedbelow:

Lab-scale unit for Fluoroorganics process development

Bench scale unit for fluoroorganics process development

NN

N

NHCH3

OO

F

CH3

Ar

Et

NHCH3

F

H3C-N

O O

N

N

Ar

H

NHCH3

F

O O

Et

NH3C-N

NH

RR1

NHCH3

F

O O

Et

NH3C-N

NH

CF3

NH

N

Ar

O2N

CF3

NH

O2N NH

R

R1

CF3

NH

O2N NH

(CH2)n

(CH2)n

49

16 compounds sent to Bayer Crop Science,Germany(Herbicidal, Fungicidal, Insecticidal)

Benzo[b]furans

Quinazolinones

Total compounds = ~ 50Synth. Commun. 32, 2467 (2002)J Fluorine Chem. 124, 203 (2003)Product patents - 2Process patents - 3

Benzoxazepines(Cholesterol regulating agents)

1,3-oxazino[5,4-b] Indoles(Synthon for Benzoxazepines)

Tetrahedron 60 (2004) 12231-12237

Fluoroorganics

R NH2

CF3

CONH2

CONH2

CF3

NH

NH

H

R'

O

R

CONH2

+

MnO2MnO2

N

NH

CF3

R

O

CONH2

R1

RNH

2

CF3

CN

CN

R

NH

NH

R'

H

O

CONH2

F3C

N

NH

R

F3C

O

CONH2

R1

J Flourine Chem. 118, 73 (2002)

Tetrahedron 61 (2005) 3999-4008(Synthon for Benzoxazepines)

N

O

O

CF3

R

R"CN

R'

H

COOH

CF3

NH2

CN

CN

R

PhMgBr

CF3

NH2

CN

R

Ph

NH+

(Major)

R

NH2

CN

NH

Ph

F3C

(Minor)

CF3

NH2

CN

Ph

OH

H

Ph

CF3

NH2

CN

Ph

O

Ph

Zn(

BH

4)2

50

Applied Research

Innovative processes employing catalysts were

developed for the first time which were unique in nature

in all respects, basic & engineering, and these

technologies opened up new frontiers in the areas of

Asymmetric synthesis, Solid acid-bases and Oxidation.

The new catalytic materials perform catalytic reactions

to achieve the highest possible atom economy in an

effort to realize cutting edge technologies and to meet

stringent environmental specification in pollution

abatement. The following process technologies

culminated out of the efforts in this direction.

Synthesis of TBBA

Synthesis of TBBA, a fire retardant has been

demonstrated to BILT Industries on a lab scale in batch

mode. This process is a mimic of haloperoxidase enzyme

observed in nature, utilising both the atoms of bromine

molecule. This is an unique technology with the catalyst

developed by IICT. Continuous pilot plant studies with

a capacity of 1.2 tonnes per day are completed.

Commercial plant with the capacity of 10,000 tpa is being

set up, based on the technology developed by IICT.

(Sponsored by : M/S. Solaris)

Selective air oxidation of toluene to benzaldehyde

Selective air oxidation of toluene to benzaldehyde has

been demonstrated to M/s. Vinati Organics Ltd. The pilot

plant studies are at an advanced stage for compilation

of data to set up commercial plant by Vinati Organics

Ltd. with the capacity of 15,000 tpa.

Solid acid catalysts for nitration

Friedel-Crafts reactions are very important to obtain

intermediates for drugs, pesticides, perfumes and

fragrances, etc. The major disadvantages encountered

with the use of classical AlCl3 and H

2SO

4 include corrosion,

environmentally unfriendly and expensive due to the

requirement of excess of reagent and waste by-

products.

Nitration of toluene: The most significant achievement

is the selectivity i.e., the nitration of toluene provided a

product mixture containing >60% p-isomer as against

the 34% by conventional method. The present process

has been demonstrated to M/s. Vasant Chemicals Ltd.

Pilot plant studies for continuous process are

completed and due for demonstration. Sponsored by

Vasant Chemicals Ltd. and Deepak Nitrites Ltd.

Development of LPG gas sensor using Nanotechnology (DST, New Delhi)

Nanosized SnO2 powders were synthesized using

anionic surfactant as template. The particle size was

controlled in the range between 4 – 12 nm with a BET

surface area of 125m2g-1.Thick film LPG sensor was

fabricated using the synthesized SnO2nanopowder and

its electrical response of the sensor to LPG to 200 ppm

was studied by sensitivity measurement.The Sensitivity

of nano - SnO2

was high compared to conventional

SnO2 powder at the same operating temperature.

Nanostructured Semiconducting Oxidebased materials for development ofAmmonia Gas Sensor. (Department ofAtomic Energy)

Mesoporous Zinc oxide was identified as good

candidate for ammonia gas sensing synthesized by Sol-

gel route with particle size of 8 nm which increased to

14 nm at elevated temperature of 500oC. Gas Sensing

characteristics were carried using the synthesized ZnO

powder towards NH3 gas. Further effect of additives

i.e.,choice of additives on the bases of different chemical

reactions between the sensor and test gas, its selectivity

and fabrication of prototype of sensor element using

ZnO and WO3 material are ongoing.

Pre-commercial studies on adsorbed naturalgas technology (Gas Authority of India Ltd(GAIL), New Delhi sponsored project)

This project is executed as a collaborative project with

INORGANIC & PHYSICAL CHEMISTRYINORGANIC & PHYSICAL CHEMISTRYINORGANIC & PHYSICAL CHEMISTRYINORGANIC & PHYSICAL CHEMISTRYINORGANIC & PHYSICAL CHEMISTRY

51

Coal, Gas and Energy Division of IICT. Characterization

of composite blocks for pore size distribution and

surface area carried out in order to check the maximum

methane storage. Adsorbent composite blocks

prepared by mastering the manufacture procedure of

composite blocks to their application in the filed of

natural gas adsorption are being carried out.

Furthermore characterization of adsorbent is carried

out to evaluate and correlate their efficiency.

BASIC RESEARCHSynthesis new dye molecules for DyeSensitized Solar Cells (DSSC) applications

(IICT- Aisin Cosmos R&D Co., Ltd Japan Collaborative

Project)

Nanoparticles in Catalysis

Nanoparticles, very active catalysts are to be stabilized

via immobilization process in order to prevent

agglomeration during catalytic reaction. In this

direction, nanoparticle immobilized clays and

nanozeolites weredeveloped for catalytic organic

transformations. These catalysts successfully displayed

superior activity to the tune of 5-20 fold excess than

the currently known catalysts in the aldol , Heck ,

Michael, nitroaldol, Wadsworth-Emmons reactions and

synthesis of tetrazoles.

Solid Acid Catalysts

Montmorillonite and zeolites are versatile hosts for

various Brönsted and Lewis acid catalyzed organic

transformations such as nitration, acylation, alkylation,

sulfonylation, etc. Molybdenum or tungsten oxide

modified zirconia catalysts obtained by an

unconventional method exhibit very strong acidity

and interesting catalytic activity for the facile synthesis

of 1,1–diacetates from aldehydes under solvent free

conditions. The major advantage of Mo- or W- modified

zirconia, over sulfated catalysts, is that the former does

not suffer from dopent loss during thermal treatments

and also undergoes significantly less deactivation

during catalytic runs. An efficient synthesis of 1,5-

benzodiazepine derivatives catalyzed by the solid

super-acid sulfated zirconia catalyst was also

developed.

Solid Base Catalysts

C-C bond formation reactions are of prime importance

for fine chemical and bulk chemical synthesis. Solid

bases conceived, designed and synthesised are found

to be very good catalysts in C-C bond formation

reactions such as Aldol, nitroaldol, Knoevenagel,

Michael, Wittig-Horner, aza-Michael, arylation and

cyanosilylation of carbonyl compounds . These are the

promising candidates to replace soluble bases, which

are contributing for the effluent generation in

enormous amounts.

Asymmetric Catalysis

The work involves a design and synthesis of new

complexes homogeneous as well as heterogenisation

via immobilisation of the resulting complexes on

natural and synthetic zeolites, anionic clays,

nanomaterials for asymmetric cyclopropanation,

epoxidation, dihydroxylation and hydrogenation

reactions. Design and development of innovative

anion exchange technique to immobilise OsO4

2- on

hydrotalcite, resin, silica supports to perform

asymmetric hydroxylation successfully is the landmark

in the asymmetric dihydroxylation area. The diols thus

obtained have wide spectrum of applications as

intermediates in drugs such as taxol and diltiazem.

Transmission Electron Microscope (TEM)

Inorganic & Physical Chemistry

52


Catalysis in Ionic Liquids

Ionic liquids offer the opportunity of combining the

advantages of both homogeneous and hetero geneous

catalysis in one system. That is to say, immobilization of

a catalyst ( metal/oxide/complex) by supporting it in an

ionic liquid rather than on a surface may create highly

free, three-dimensional centers as in a homogeneous

catalyst but the catalytic reaction occurs at the interface

between the ionic liquid and the reactants in either the

gas or immiscible liquid phase. Application of ionic

liquids in chemical processes has blossomed only within

the last decade. Metal complexes immobilized in ionic

liquids are used in Aza-Michael , sulfimidations and

aziridnations reactions.

Silver Catalysts in Controlling Micro-or ganism in Water

Ag catalysts supported on carbon and carbon coverd

alumina, prepared by electrochemical deposition exhibit

superior activity in controlling microorganism in water

compared to those prepared by impregnation

technique.

Catalysts for Ammoxidation

A new type of catalyst, based on heteropolyacid, was

developed for obtaining high (more than 90 %)

selectivity to the nitrile. A novel method, called the in

situ synthesis method, was developed for the

preparation of ammonium salt of heteropolyacid.

Carried out extensive work on VPO catalysts for the

ammoxidation of methylpyrazine. The studiy was

extended to ammoxidation of cresol using mixed metal

phosphate catalysts. Established the noval

potentiometric titration technique for acidity

determination.

Catalytic Chlorination of Ethane

Development of a catalyst system that could convert

ethane and chlorine into vinylchloride, ethylene and

hydrogen chloride was taken up. After separation of

VCM, the other two products could be easily converted

again into additional VCM by the established catalytic

processes. This process is a better option compared to

the alternative process based on ethane

dehydrogenation which is highly energy intensive and

offers lower yields. A lab-scale reactor for the

preliminary catalyst evaluation was set up with on-line

analytical facilities. Several catalysts were prepared and

their preliminary evaluation was carried out. The best

catalyst was identified. Standardization of the reaction

conditions to obtain optimum yields of VCM, ethylene

and HCl. Reproducibility studies were conducted on

catalyst preparation.

Pd based Catalysts for the Hydrodechlorination of Chloroaromatics & CFC-12

Pd based catalyst for HDC reaction was synthesized by

adopting three different methods namely

impregnation, deposition – precipitation and

microwave heating. The supported catalysts were

prepared by impregnating the commercial supports

ZrO2, Al

2O

3, CeO

2, Nb

2O

5, SiO

2and CeO

2. Two types of

catalysts were evaluated for activity studies. (i) catalyst

with high Pd content (up to 10 wt. % Pd) and (ii) catalysts

with low Pd content (1 wt. % Pd). The HDC runs were

carried out on these catalysts. Catalysts prepared by

DP method with chloride precursor provided a

convenient approach for the preparation of active and

stable catalysts with low Pd content. The nature of the

active site was evaluated after a thorough

characterization.

Development of Solid Catalysts forBiodiesel Synthesis

The existing catalysts for the esterification and

transesterification of vegetable oils for biodiesel

production are essentially based in homogeneous

catalysts or mineral acids and alkalies. Since the

processes based on these conventional catalysts are

53

not eco-friendly, attention was focused on development

of solid catalysts. As a part of this programme

esterification of palmitic acid with methanol was carried

out on various solid catalysts like zeolites, solid super

acids and heteropolyacids and their salts.

Novel nano-sized CeO2 based mixed oxide

catalysts for three way catalysts (TWC) andother applications

Novel nano-sized CeO2/ZrO

2 and CeO

2/TiO

2 combination

carriers were prepared and characterized by various

physicochemical techniques. The relative influence of

SiO2, TiO

2 and ZrO

2 on the OSC properties CeO

2 was also

systematically investigated.

Microwave assisted combustion synthesis ofnano-oxides

A nanocrystalline titania-silica (1:1 molar ratio) binary

oxide was synthesized by microwave induced

combustion process in a modified domestic microwave

oven (operated at 2.45 GHz frequency and 700 W power)

in ~60 minutes from in situ synthesized titanyl nitrate

and siliconyl nitrate using urea as fuel. For the purpose

of comparison, two different types of TiO2-SiO

2 powders

were also synthesized by the sol-gel and coprecipitation

methods. The TEM in particular confirmed the presence

of nanosized particles in the microwave induced

combustion synthesized powder. Among the three

analogies, microwave synthesis was found to be

superior in terms of ease of processing leading to time

and power savings.

Catalyst Design for one Step Synthesis of2,6-Dimethylphenol

Novel V2O

5/In

2O

3-TiO

2 catalyst system was designed and

thoroughly investigated for the methylation of phenol

reaction .

Aromatization of Isophorone to 3,5-xylenol

The role of acidic and basic sites of the catalysts were

studied in the aromatization of isophorone to 3,5-

xylenol by selectively blocking either acidic or basic sites

by pumping NH3 or CO

2 respectively.

NOx Abatement Catalysts

A systematic investigation was undertaken to make

titania-based mixed oxide supports for selective catalytic

reduction (SCR) and other applications. In this study

various mixed oxide supports were designed and were

characterized by different physicochemical techniques.

Defluoridation of Ground water

Adsorbent technology is adopted for the removal of

excess of fluoride ion in ground water. Carbon and

alumina based adsorbents with dopants are studied

for this purpose and the results are quite encouraging.

Nonlinear Optics

Computational evaluation of nonlinear optical (NLO)

properties of some Donor-Bridge-Acceptor (D-B-A) type

of molecules have been carried out. The systems studied

are either 3D molecules (or octupolar), zwitterionic and

nonzwitterionic Push-Pull type of organic molecules. The

main focus of this work was to model efficient organic

molecules with very large NLO activity, absorption

transparency to the visible region and various other

spectroscopic and charge transfer related properties.

Besides the theoretical modeling, some of these NLO

molecules are also synthesized and their characteristic

properties were also estimated experimentally. These

results show the existence of a good correlation

between the modeling and experiment.

Molecular Electronics

Frontier Molecular Orbital (FMO) studies have been

applied to analyze the electron transport characteristics

of some D-B-A type of molecules. The studies show that

the electron transfer and conductance properties of

these molecules largely depend on their differential

bonding patterns and structural orientations. In this

Inorganic & Physical Chemistry

54

regard some potential molecular wires and molecular

rectifier are suggested.

Organic Light Emitting Diode

The main interest lies in modeling of suitable organic

molecular materials, which probably can find

applications in electro luminescent (EL) layer of organic

light emitting devices (OLED). In this regard our

modeling studies suggest some ? and ? substituted

anthracene derivatives as active EL materials.

Transient Molecules

Theoretical as well as mass spectral analysis of some

elusive molecules, which have lifetime in pico second

range have been undertaken. These studies have

significant importance in the field mapping organic

reaction mechanism (i.e., possible finding the nature of

various intermediates and transitions states),

interstellar and circumstellar reactions (these studies

can give some clue in finding new stellar entities).

Functional Dyes

The studies are directed in the investigations of new

functional dyes, which can find applications in various

fields like solar cell and various optical devices.

Binary Clusters

Studies on Au-Cu clusters are carried out by using

various computational techniques for small

clusters[clusters with fixed size of n=6 while varying the

composition of the cluster from pure Cu (Cu6) to pure

Au (Au6) through Au

xCu

6-x (x= 1- 5)] and the

observations extrapolated to larger clusters to

understand the effect of the shape of the cluster on

common properties like dipole moment and

absorptions which give us a fair understanding of the

natur of crystallization into such matrixes as not only

energy but also dipoles which play an important part

in crystallization.

Separation of Hf from Zr Tailings

With the general view of understanding the interactions

of Zr and Hf metal complexes with the solvents and

with the more specific aim of developing an efficient

extractant, theoretical study was done. Our aim is to

get the quantitative picture of the interaction energies

(primary interactions), which will give an insight into

the nature of Zr/Hf interacting with TBP/MIBK. Here the

main goal is to understand the molecular level

interactions (gas phase) of Zr and Hf complexes with

P=O group and the C=O groups, and what

conformations do these complexes adopt with the

ligands. For this we define some energy terms, which

should help to understand which metal complex (Hf or

Zr) has more preference in the solvent and what would

be the gain or loss in energy when it passes from the

aqueous media to the organic phase. Studies were

carried out using the ab initio/DFT software, Gaussian

98(G98) which is based on the Gaussian orbitals and

also using Amsterdam Density Functional package

(ADF) which is based on the Slater type orbitals.

Bandgap engineering: Doping titania with anions

like C, S, N extends the absorption into the visible

spectrum. This shift is accompanied by a concomitant

narrowing of the band gap.

Photocatalysis Ag-TiO2: Using TiO

2 nanoparticles

as the photocatalyst, reduction of silver nitrate to silver

metal was done to make a new metal-metal oxide

nanocomposite.

Nanostructured morphology by templating:

Synthesis of nanostructured â-FeOOH and thereby a-

Fe2O

3 with different architectures by a simple process

by controlling the synthesis parameters.


55

The Lipid Science & Technology Division has been

transformed into more industry-friendly during this

period. The Division has refocused its R & D in

upgradation of traditional processing methods and

new technologies for downstream products of

commercial importance using modern approaches like

biotechnology and membranes. The Division ushered

lipid biotech revolution during this period by

developing enzymatic degumming technology for rice

bran oil.

ENZYMATIC DEGUMMING OF RICE BRANOIL

Rice bran is a valuable co-product of the rice milling

industry and its oil content ranges from 12-25%

depending upon the quality of the bran. Chemical

refining of rice bran oil generally results in losses

considerably higher than those encountered in other

vegetable oils due to the presence of larger amounts

of free fatty acids and non-triacylglycerol constituents.

Refining losses can be considerably reduced by using

physical refining. For successful implementation of

physical refining, the most important pre-requisite is

the efficient removal of gums. Many Indian oil-

processing units have adopted physical refining

without taking measures to lower the content of

phosphorus. This is resulting in producing dark colored

oils, which fetch less value in the market. Enzymatic

process is the answer for the entire problem as it

catalyzes the conversion of non-hydratable

phospholipids into water-soluble lyso-phospholipids,

which are then removed by centrifugation, yielding

degummed oil with lower phosphorus. During this

period IICT came out with an efficient enzymatic

degumming technology for rice bran oil (patent filed)

employing a commercially available enzyme to bring

down the residual phosphorus levels to 0 to 5 ppm

after bleaching and dewaxing. This oil, if refined in a

well-maintained physical refining unit, will produce good

quality edible rice bran oil. The enzymatic degumming

process is less energy intensive, minimizes the loss of

oil, and reduces water consumption and more

environmental friendly.

This is one of the outstanding projects of IICT in terms

of its reach and impact on the Indian Vegetable Oil

Industry. During the last three years IICT has transferred

this process to about 14 rice bran refineries and 8 Project

Engineering Companies (as licensee) spread over 9

states for implementation of enzymatic degumming

technology. Execution of the project at another four

industries is in advanced stage. The Technology Mission

on Oilseeds, Pulses and Maize (TMOP & M) came forward

to extend a grant-in-aid assistance of Rs.75 lakhs each

to 15 industries (out of the above 19) for establishing

50 tpd rice bran oil refinery by employing IICT’s

degumming process.

ECO-FRIENDLY SYNTHETIC AVIATIONLUBRICANTS

Environmental considerations and dwindling

petroleum reserves are likely to see the emergence of

LIPID SCIENCE & TECHNOLOGYLIPID SCIENCE & TECHNOLOGYLIPID SCIENCE & TECHNOLOGYLIPID SCIENCE & TECHNOLOGYLIPID SCIENCE & TECHNOLOGY

Degumming Commercial Unit from Industry Synthetic Aviation Lubricant (SAL) experimental unit

56


oleochemicals as viable alternative feedstocks for

synthetic lubricants. IICT has initiated several

programmes in this direction and one such project is

the development of synthetic aviation lubricants. A

consortium of six leading Indian Institutes with IICT as

the nodal agency was formulated with a proposed

project cost of over Rs.17 crores for executing this

project. The project is sponsored by Centre for High

Technology (CHT), Ministry of Petroleum & Natural Gas,

Govt. of India to the extent of Rs.8.4 crores. CSIR, DRDO

and participating organizations share rest of the project

cost. The project was initiated in December 2002. The

role of IICT in the project is to develop a pilot scale

process for the preparation of SVS 1 and SVS 2 base

stocks for synthetic aviation lubricants. Physico-

chemical properties like TAN, Viscosity, Pour point, Flash

point etc., are the inherent properties of the base stock.

Sophisticated analytical testing equipments to

determine Viscosity (at low and high temperatures),

Pour point, Flash point, Foam Tendency, Evaporation

loss, Corrosiveness and Oxidation stability. During this

period, laboratory scale experiments were carried out

for the synthesis of base stocks with the required

specifications. A 5 kg/batch esterification reaction

system has been designed, fabricated and

commissioned to collect data for the design of the pilot

plant.

BIODIESEL

Biodiesel is an eco-friendly fuel originating from

renewable source. It can partly or totally replace the

petroleum based diesel. Presently biodiesel is being

used by several countries like Germany, Austria, USA,

Canada, France. In order to hasten the biodiesel usage,

the Planning Commission of India has recommended

launching of National Mission to initiate the plantation

of oilseed crops like Jatropha and Karanja followed by

gradual introduction of biodiesel blending in diesel

upto 20% by 2011. IICT was actively participated in the

preparation of Biodiesel Report of Planning

Commission and also helping AP State Government by

participating in its Task Force formed for the

implementation of biodiesel programme in the state.

TMOP&M has provided a funding of Rs. 40 lakhs for

executing a project on “Development of pilot scale

process for biodiesel from high FFA oils and acid oils”

during 2004-06. Work was initiated on two step catalytic

process using acidic catalyst for esterification and

transesterification of glycerides in the Jatropha oil at 5

and 50 kg oil per batch. Work has been imitated on

other catalysts such as biocatalysts (lipases) and solid

chemical catalysts. Both esterification and

transesterification methodologies are being optimized

using all the potential oil sources like Karanja. Work

has also been initiated for the development of a

continuous process for handling multi-feed stock. A

project proposal entitled “Studies on Physico-Chemical

Properties of Jatropha Seeds and Continuous Process

Development for the Preparation of Biodiesel” was

submitted to AP State Government for financial grant.

IICT is also looking at developing potential applications

of by-products such as unsaponifiable matter, oilseed

cake, glycerine etc., The scientists of IICT delivered a

number of invited lectures at different workshops,

conferences, brain storming meetings to strengthen

the biodiesel movement in the country.

VALUE-ADDED PRODUCTS FROMVEGETABLE OILS AND BY-PRODUCTS OFPROCESSING INDUSTRIES

Rice bran wax: Rice bran wax (3 to 6% of crude

oil) is a by-product obtained during dewaxing

process. A simple and efficient bench-scaleBiodisel experimental unit

57

process (patent filed) was developed for the

upgradation and bleaching of crude rice bran

wax. The upgraded wax may substitute the

imported carnauba wax fully or partially. The

process has been demonstrated to four

industries. One Project Engineering Company

has taken license for this project.

Hydrogenated rice bran wax: A Process for the

hydrogenated wax was also developed and

transferred to one industry.

Triacontanol / polycosanol: Triacontanol and

polycosanol are presently being marketed as

plant growth stimulant and cholesterol

reducing agent respectively. IICT has developed

a bench-scale patented process for the recovery

of these two products from crude rice bran wax

and transferred the process to three industries.

Oyrzanol: The soap-stock generated during

alkali refining is a good source for g-oryzanol, a

biologically active component used in foods

and pharmaceuticals. A process was

standardized on laboratory scale for the

isolation of oryzanol in about 70% yields with

about 65-95% purity (Two Patents granted).

Lecithin and Lysolecithin: Lecithin and

lysolecithin are the by-products of water and

enzymatic degumming processes of rice bran

oil. These products have lot of potential in food

and pharmaceuticals applications. A laboratory

scale-process was developed for bleaching of

these products and the products are being

characterized and evaluated for newer

applications using a financial grant of TMOP&M

in collaboration with Project Directorate on

Poultry, ICAR, Hyderabad

Phytic acid and Inositol: Phytic acid is present

to the extent of 3-10 in rice bran and is endowed

with attractive biological properties. A bench-

scale process was successfully developed for the

extraction of phytic acid from deoiled rice bran.

A laboratory scale process was also optimized

for the preparation myo-inositol from phytic

acid (TMOP&M sponsored project)

Preparation of novel phospholipids from soya

lecithin: During the execution of this project,

main thrust was given to add value to soybean

oil gums as there is lot of scope for the Indian

soybean oil industry to exploit soya lecithin for

their economic growth by preparing food grade

and modified lecithins for various applications.

Reaction conditions were optimized for the

preparation of various products from soya

lecithin namely Non-hydrogenated solid

lecithin, Hydroxlated lecithin, Epoxy lecithin,

Lysolecithin, and Development of chemo-

enzymatic method for the preparation of

phosphatidylcholine with desired fatty acids

(DBT sponsored project)

Synthesis and evaluation of reduced calorie

fats: Reduced calorie fats are not being prepared

in our country and there is no indigenous

technology available for the preparation of such

type of compounds. A novel structured fat was

synthesized enzymatically with improved

nutrition and reduced calorific value (5.3 kcal/

mole) from easily available renewable sources.

The reduced-calorie plastic fat has the

consistency of vanaspati without any

deleterious trans fatty acids. The presence of

essential fatty acids and natural antioxidants

makes the reduced calorie fat superior to the

other reduced calorie fats available in the

international market. This is completely a new

area of research in our country. The upscaling

studies of some selected novel reduced calorie

fats are in progress with the financial grant

received from DBT.

Synthesis of alkyl ricinoleates and 12-hydrocy

stearates: A simple enzymatic method was

Lipid Science & Technology

58


developed for the preparation of cosmetic base

materials like alkyl ricinoleates and 12-hydroxy

stearates without formation of estolides. These

compounds were sulphated and found to

exhibit good surfactant properties.

Preparation of ricinoleic acid and 12-hydroxy

stearic acid estolides and evaluation of their

sodium and sulfated sodium salts for

surfactant properties: Estolides exhibit high

viscosity indices, good oxidative stability and

are biodegradable. These compounds have a

variety of potential applications as base

materials in lubricants, greases, plastics, inks,

cosmetics, and surfactants. In the present study

ricinoleic and 12-hydroxy stearic acid estolides

were prepared with varying molecular weights

and evaluated for their surfactant properties as

their sodium salts and sulfated sodium salts. The

sulfated sodium slats of monomer, dimer and

trimer exhibited superior surfactants properties

compared to their corresponding sodium salts

Enzymatic fat splitting: Enzymatic fat

hydrolysis is a very mild process and has many

advantages over the conventional fat splitting.

A laboratory scale method was developed for

the enzymatic fat splitting using soybean and

rice bran oils and also for hard fats like

hydrogenated castor oil, sal and mango fats

using thermostable lipases. Further work is in

progress to upscale the process (Sponosred by

Directorate of Vanaspati, Vegetable Oils & Fats)

Sebacic Acid: Sebacic acid is used in the

manufacture of commercially important

plasticizers and lubricants. The process has

been optimized in continuous mode (0.5 kg/hr)

using the funding of TIFAC (DST).

Miscellaneous projects: During this period Lipid

Science & Technology Division has initiated

work in variety of specific areas like

Development of Specialty fat liquors

(Sponosred by Balmer Lawrie Ltd., Leather

Chemicals Division, Chennai), Evaluation of

Bbended edible oils containing EPA & DHA

(Sponsored by M/s Recon Oil Industries,

Mumbai), Recombinant approach to produce

µ-linolenic acid and docosahexaenoic acid

(DHA) in Sunflower and Yeast (NMITLI project,

Avesthagen Ltd., Bangalore as an industrial

partner), Explorative studies on eripupae and

eripre-pupae Oil (Sponsored by Central Silk

Board, Bangalore)

Value-added products from glycerol pitch:

Glycerol pitch is a by-product of fat splitting and

the industry is struggling to even dispose this

material. Work was initiated to purify and

prepare variety of esters with good surfactants

properties (Sponosred by Directorate of

Vanaspati, Vegetable Oils & Fats).

TASK FORCE PROJECTS

The Lipid Science and Technology Division is also

participating in the following from Task Projects of CSIR

for the development of new generation lubricants,

nutraceuticals and enzymatic extraction of oil from rice

bran.

Task Force on Technologies for Organic Chemicals

� Enzymatic Extraction of Rice Bran Oil (IICT & RRL-T)

� Gamma Linolenic acid from agro products (RRL-

J, RRL-T & IICT)

� Pilot scale process for the isolation of

phytosterols from vegetable oil deodorizer

distillate (RRL-J, IICT)

Task Force on New Generation Fuels and Lubricants

(Nodal Agency – IIP)

� Development of Biodegradable lubricants from

vegetable oils (IICT, IIP)

Task Force on Nature and nature-like bio-active

molecules (Nodal Agency-CFTRI)

59

� Potential synthesis of oryzanol (IICT, CFTRI)

Task Force on Positioning Nutraceuticals and

nutragenomics in global platform (Nodal Agency:

CFTRI)

� Development of scale-up of laboratory scale

process for the production of lecithin and

glycolipids (IICT, CFTRI)

� Enzymatic modification of specific oils and fats

for tailor made nutritional and functional fats

(IICT, CFTRI)

MEMBRANE SEPARATIONS

Membrane Separation sciences is one of the newer

separation techniques used in the industries. Though

the use of this technique in aqueous system is well

known, information regarding its uses in non-aqueous

system is too sparse and there exist tremendous scopes

for developing some uses for non-aqueous system like

in vegetable oil. IICT has initiated a project in

collaboration with CGCRI with a financial grant of

TMOP&M on “Development of technology package for

ceramic membrane module for ultrafiltration of

vegetable oils for physical refining”. In this project, CGCRI

has to develop the UF ceramic membranes and IICT has

to evaluate their performance for degumming of rice

bran and soybean oils and work is in progress.

IICT has developed a process for recycling/reuse of the

wastewater coming out of a physical refining unit of a

vegetable oil refinery and presently IICT is trying to

upscale the process. It has also developed a similar

process for Dairy wastewater also. The water quantity

obtained after the membrane treatment was found to

be very good and that can be recycled back to the

process.

BASIC RESEARCH

Lipid Science & Technology Division has taken up many

initiatives to spread their research base into varieties of

areas like low calorie fats, infant milk substitutes,

structured fats for novel applications, oleochmical-based

lubricants, surfactants, cosmetics and perfumery, novel

methodologies for derivatization of unsaturation and

carboxylic group of fatty acids, leather chemicals, animal

fats for possible applications in industrial and

nutraceutical sectors.

Development of New Lipid based DeliverySystems for Bio-actives

A series of novel cationic amphiphiles have been

designed & synthesized and the gene transfer properties

of these new generation of cationic transfection lipids

have been evaluated. Our results have enriched the

field of liposomal gene delivery. (DBT-funded project).

Six novel cationic transfection lipids have been designed

& synthesized and sent to Dabur for evaluation of their

gene transfer properties (Dabur Research Foundation

(DRF) sponsored project). A series of novel

histidinylated cationic amphiphiles have been designed

and synthesized. Studies aimed at exploring the

potential of these novel cationic lipids in DNA

vaccination are in progress (DBT sponsored project).

Bulk preparation of two of our most in vivo promising

cationic transfection lipids have been completed aimed

at exploring their potential use in healing chronic

wounds (IICT-Virchow Biotech-DST project). The initial

in vitro experiments using cultured animal cells towards

exploring the potential of our novel RGD-lipid in

targeting tumor vasculatures have been completed. A

number of publications in high impact factors journals

and overseas patents have resulted from this important

research carried out both independently by IICT and in

collaborative research with CCMB, Hyderabad and CNRS,

France.

Lipid Science & Technology

60

APPLIED RESEARCH

Development of special grade epoxy

novolac system suitable for canister ( PJ-10)

application, Defense Research and

Development Laboratory (DRDL),

Hyderabad

Filament winding is an important fabrication technique

for making large composite structural parts. Epoxy

resins are being widely used for this purpose because

of good mechanical and retention of properties under

severe operating conditions. This technology is not

available to India due to strategic reasons. The

development of this technology is critical to our

supersonic missile technology for launching the

missiles from submarines. IICT has identified the

constituents of the resin system of Russian origin and

developed a resin system suitable for manufacture of

prepregs meeting the specifications of the Russian

made samples. Technical report has been submitted to

sponsor on completion of the project.

Low loss polyester resin for aircraft radomes

Radome, a thin cover protecting radar, is a functional

composite structure made up of reinforcing fibers

embedded in a resin matrix. IICT has developed a resin

system useful for the fabrication of Radome. The

performance of radar depends on the quality of

radome, which transmits the signals back and forth for

identifying the targets. The resin system has passed all

the test parameters and the process has been

approved by ADA after stringent testing procedure.

The resin was produced in our pilot plants and supplied

to sponsors, ADA, Bangalore (500Kg) and to HAL,

Bangalore (350Kg).

Synthesis and Development of new

Biodegradable and Biocompatible poly

mers for Tissue Contacting Applications

Work has been completed successfully and report

submitted to sponsor Department of Science and

Technology, DST, New Delhi

Synthesis and Development of Cyanate

Ester Based Resins for Advanced Aircraft

Applications

Work has been completed successfully and report

submitted to sponsor ADA, Bangalore

Development of Solder resistant Cfoating

This coating formulation has been developed which is

a dual curing system ie., thermal as well as UV curing

and report submitted to an overseas client.

ORGANIC COATINGS AND POLYMERSORGANIC COATINGS AND POLYMERSORGANIC COATINGS AND POLYMERSORGANIC COATINGS AND POLYMERSORGANIC COATINGS AND POLYMERS

Polymer developed in IICT used in the radome ofLight Combat Aircraft (LCA)

61

Development of Polymeric Materials for PU

coatings

Two polyols based on castor and linseed oils developed

by IICT have shown good properties compared to

imported samples. The products are ready for

commercial exploitation.

Development of Polymeric Binder for the

preparation of composites from tannery

waste

A polymeric emulsion was developed to be used as

binder for the preparation of composites using waste

material from animal skins. These composites have

shown promising results. Process may be released to

interested parties on sponsorship basis.

Development of Rain Erosion resistant

Coating

A series of segmented polyurethane resins have been

prepared and formulate a rain erosion resistant coating,

which has shown promising results. Further work is in

progress. Some of the panels have passed 180 mts. of

rain erosion test at 1 mm rain drop size and 1800 RPM

as per MIL specification.

BASIC RESEARCH

Biomaterials

Polymer adhesives and sealants have been used for

several years in medical practice for joining and sealing

tissues. During surgeries or injury a surgeon needs to

arrest fluid leaks in a patient and sutures or staples are

routinely used to control such fluid leaks. But several

internal organs are either too delicate or small for

surgeons to use methods effectively without causing

additional trauma. Development of biologically

acceptable sealants could improve a surgeons’

efficiency either by completely replacing sutures or by

augmenting them. In this work a series of hydrophobic

ally graded, in situ polymerizable liquid sealants were

prepared and investigated for sealant and drug delivery

applications. They were also found to be bio compatible

upon subcutaneous implantations in Swiss albino rats.

Fiber reinforced composites

Fiber reinforced composites made with synthetic resins

are widely used in automobile and aeronautical

industries for their advantageous strength to weight

ratio. For elevated temperature service applications,

high Tg thermo set resins are normally used. Cyanate

ester resins have recently attracted attention of

composite fabricators with their high Tg

and relative

easy, epoxy like processing. Like any other highly cross

linked thermosetting resin, cyanate esters also tend to

be brittle and need to be modified suitably to be able

to serve mechanical or structural functions. In this work

efforts have been made to improve the basic properties

of cyanate ester based composites using reactive

blending and thermoplastic modification with

polysulfone.

Organic Coatings and Polymers

62

Direct Sourcing of Coal for Value-added

Chemicals:

Coal is predominantly aromatic, coal matrix contains

basic aromatic building blocks with 2-6 condensed rings,

which otherwise are not available in any other natural

source including petroleum. These aromatics find use

in industry - or engineering plastics e.g. fibers, aromatic

polyamides and liquid crystalline polymers (LCP). The

methodology of this project is to selectively obtain the

aromatics and phenols by catalytic cleavage of

methylene and ether bridges interspersed between the

polycyclic aromatic rings. The residual coal fuel value is

also enhanced by tapping these compounds. Results

of experiments with Co-W/Al2O

3 and CO-Mo/Al

2O

3

catalysts, at reaction temperatures 150-3750C and <50

kg/cm2 pressures on catalytic degradation of coal

showed that i) the catalysts are effective to cleave the

methylene bridges in coal, ii) aromatic rings are not

hydrogenated, iii) the alkyl groups on aromatic rings

are cleaved. iv) pressures in the range 30-50 kg/cm2 are

necessary for improved yields, v) it is possible to

enhance the yield of low boiling aromatics, particularly

2- and 3-ring aromatics by choosing proper catalysts

and process conditions.

(sponsored by Ministry of Coal, Govt. of India)

Hot Gas Clean-up:

This is a collaborative work between IICT and the Centre

for Energy Technology (CET) of Osmania University,

Hyderabad. The aim is production of clean fuel gas from

coal-derived gases using reactive, regenerable sorbents

for sulfur removal and ceramic candle filters for fine

particulates control. The hot gas desulphurization setup

made of Inconel-600 alloy designed to operate at 850oC,

20 bar pressure and 20 Nlpm flow was found to be

durable during the repeated heating/cooling cycles. The

sorbents selected for the studies on sulfur removal

from coal gas mixtures include 3 mm pellets of Zinc

oxide (on Zeolite) and Zinc ferrite with high affinity to

sulphur while those with low affinity to sulphur include

Iron Ortho-silicate and Iron Chromite. Online analysis

of different process gas streams such as Feed, Clean

gas, sour gas is done by an on-line Gas Chromatograph

with (TCD + FID + FPD) assembly. Dust removal trials

are completed and sulphur removal/recovery trials are

in progress.

Trial runs of adding coal ash using a Dusty Gas Simulator

into the hot air stream at 20 bar pressure and 850oC

and subsequent removal of dust in the candle filters

were successfully completed. Removal of the dust by

dedusting the candle filter surfaces by frequent back-

pulsing with hot nitrogen (40 bar, 200oC) was carried

COAL, GAS AND ENERGY COAL, GAS AND ENERGY COAL, GAS AND ENERGY COAL, GAS AND ENERGY COAL, GAS AND ENERGY

Hot gas clean up unit for IGCC application

63

out and dust collected in the filter vessel was

successfully reclaimed. Number of experiments using

air were completed. Experiments using simulated gas

mixtures could not be completed as the heater coils

got snapped during the experimentation. Collection of

process & analytical data on Desulphurisation is in

progress. One high-affinity sorbent (ZnO) and one low-

affinity sorbent (Fe2SiO

4) were packed in the dual bed

adsorbers. Simulated gas mixtures containing CO2,

hydrogen, nitrogen and COS were prepared,

compressed and stored at 60 bar in the storage cylinder.

Gas at 20 Nlpm flow rate and 20 bar pressure was heated

to 850oC in the gas heater, passed through the adsorbers

at 850oC and outlet gas was analysed. 100% carbonyl

sulfide removal was achieved. Work is in progress for

evaluation of data and preparation of Technical Report.

(Sponsored by Ministry of Coal, Govt. of India).

CO2

Free Hydrogen (NMITLI)

The project is aimed at study, evaluation and

development of carbon / Ni catalysts to obtain CO2

free

hydrogen by thermocatalytic decomposition of

methane. IICT prepared and evaluated catalysts of IICT

along with IIP and commercial Engelhard catalysts in

fluidized bed reactor. 10 hours catalyst life with a

methane conversion of 140-40 mol/gr – 1/S-1 is achieved

while producing pure H2

and C. The carbon deposits

matched with methane conversion. Catalyst

characterization studies are in progress to select

suitable catalyst to meet the project objectives.

Fuel Cell Power Pack (50 kW) with Methanol

as Primary Fuel

This project is sponsored by Ministry of Non-Conventio

nal Energy Sources (NMEs), New Delhi.

The existing 10 kW methanol reforming system was

modified for better heat transfer and more efficiency.

After modification, the reforming unit was continuously

operated totally about 500 hours for system endurance.

During operation design data was generated for scaling

up the unit to 50 kW level. The hydrogen rich gas was

produced from the methanol reformer containing

about 1% of CO. It has to be reduced to about 10 ppm

level to suit for the PEMFC application. Work has been

carried out using both low temperature shift and

preferential oxidation of CO. Based on the results it was

proposed to integrate the reformer with two stage

PROX. The mechanical design of the methanol reformer,

gas clean up, equipment, and heat transfer unit and

other sub-systems has been completed. Specifications

were drawn for all the instruments. Order has been

placed for fabrication of the 50 kW methanol reforming

system. The unit is expected to be delivered shortly.

Work is in progress for commissioning and testing of

the 50 kW Methanol Reformer and demonstration of

the reformer – Fuel Cell integrated unit.

Coal, Gas and Energy

64

Chemical and Instrument Analysis plays a pivotal rolein R&D and manufacturing practices. It has developedtremendously over the years with the help ofsophisticated analytical instruments. R&D for NCEs,nanotechnology, biotechnology, composite materialsand pollution control could not have been possiblewithout the leverage of chemical and instrumentanalysis. It has immensely contributed to productquality, cost control, minimization of waste andenvironmental regulations.

Chemical & Instrument Analysis Division at IICT playsan important role in providing analytical services in theprocess development activities in different areas of R&D.The Division, in brief, provides the following services:

1. Analytical support to R&D projects

2. Supports different governmental agenciesthrough analytical services

3. Gives quality assurance and assessment ofindustrial and consumer goods

4. Carries out basic and applied research inanalytical chemistry and

5. Supports human resource development byorganizing training courses, seminars,workshops, etc.

The Division provided service to many industries,government agencies and consumers in assessing thequality of industrial and consumer products.

APPLIED RESEARCH

Synthesis and characterization by EI, CI and ESIMass Spectra of the precursors for sulfurmustards, schedule compounds under CWC.

Synthesis and differentiation of isomeric O, O-dialkyl N,N-dialkyl phosphoramidatecompounds by EI mass spectroscopy.

Identification and fingerprinting of aroma andvolatile organic compounds in short grain andBasmati rice by GC-MS. The major aromacompound 2-acetyl pyrrolidine (2-AP) wasquantified. Methyl nicotinate was also foundand monitored by GC-MS.

Isoproturon and chloroyriphos pesticides asCertified Reference Materials were made andreleased. Cypermethrin and Fenvelarate areunder process for release.

HPLC method for residue determination ofAzadiractin in tobacco leaves was developed.

HPLC method for flavonoid compounds inPigeonpea (Cajanus cajan) was developed.

An HPLC method was validated for Topiramate.

Impurity profiling and validation as per ICHguidelines for Cyclosporin – A

HPLC method for lactic acid and GPC methodfor polymeric lactic acid

Characterization of homo polymers/ copolymers of acrylic acid and acrylamide using GPC.

BASIC RESEARCHGas phase acidities for a series of dicarboxylicacids were estimated

Gas phase basicity values for galactose,mannose and talose were measured for thefirst time

A chemical ionization method for molecularweight information of chloropicrin (CP) aknown warfare agent and insecticide wasdeveloped

Proton affinity values for fifty common matricesused in MALDI were determined.

ESI mass spectral studies of lactic acid and itsmethyl ester in presence of CO 2+, Ni2+, Cu2+ andZn2+

Gas phase generation and characterization ofdi-coordinated phosphorus species, [HS-P-OH],S=P(OH)

2 CH

3OPO+,CH

3OPNH

2+, Selenoketene

(H2C=C=Se), Selenoketyl Cumulenes (HC=C=Se)

Selenocumulene HC3Se,Methylene

isothiocyanate [CH2NCS],Neutral protonated

silanoic acid HSi(OH)2 by NRMS was done.

Electrospray ionization tandem massspectrometry was used to characterize someBoc protected non-natural amino acid peptides

CHEMICAL & INSTRUMENT ANALYSISCHEMICAL & INSTRUMENT ANALYSISCHEMICAL & INSTRUMENT ANALYSISCHEMICAL & INSTRUMENT ANALYSISCHEMICAL & INSTRUMENT ANALYSIS

65

and their gas phase interaction with alkalimetal ions.

Preparation, isolation and characterization ofminor impurities of Astaxanthin by HPLC

Monitoring photodegradation pathways withPDA, MS-MS detectors for Stilbene sulfonic acidsindustrial waste waters using HPLC

Separation and determinatin of syntheticimpurities in Sildenafil, Norfloxacin andDifloxacin by HPLC

Biodegradation and bisorption studies ofaromatic sulfonic acids in industrialwastewaters

Enantiomeric purity of chiral drugs by celluloseand amylose based phases using PDA andpolarometric detectors

Zeolite and metal incorporated zeolites asstationary phases in TLC for catalytic in-situsynthesis of complex molecules

Tissue culture of Urginea congesta andcharacterization of glycosidic components

Evaluation of Chloroxylon swietenia DC forinsecticidal and larvicidal activity

Synthesis and Atropisomerism of meso-tetrakis(4-chlorocoumarin-3-yl)porphyrins

Physicochemical properties like activitycoefficients, heats of solution were determinedfor commonly used organic solvents ondimmer acid methyl and tritolyl phosphateesters

Trace level inorganic impurity profiling ofpharmaceutical substances by ICP-MS

Method validation for bulk drug and impuritiesfor Indinavir, Zudovidine, Lamivudine andGabapantin by Capillary Electrophoresis

Studies on rain water sol chemistry using ionchromatography and electrophorosis

Heavy Metal Speciation for monitoringpollution in the contaminated areas aroundHyderabad

Phytofiltration for the removal of arsenic (III)species from arsenic contaminated waters

Statistical and Mathematical modeling to assessthe extent of pollution in the industrial areasand to predict the movement of arsenic in thegeological layers

Phytoextraction for the remediation ofpesticides contaminated soils

Atmospheric chemistry studies in north-eastern India

Detection of cellular changes duringdifferentiation of PCC4 cells by curcumin.

Electrospray ionization, tandem massspectrometry and ion-molecule reactions wereused to characterize transition metalcomplexes of 2-acetyl benzimidazolethiosemicarbazone.

The effect of spacer chain length on Li+ ionbinding to µ, w-diamine was studied usingelectrospary ionization and theoreticalcalculations.

List of Processes / Technologies Developed andtheir Importance

A process using Zeolite as statoonary phasehas been developed for the synthesis ofPorphrins, Calix(4, Pyrrle and 2 methylnapthoquinoline (vitamin K-3)

An active mosquito repellant process has beendeveloped using Chloroxylon swieteniaessential oils.

Chemical & Instrument Analysis

MALDI - TOF Mass Spectrometer

66


X-RAY CRYSTALLOGRAPHY CENTRE

The Center has established a state-of-the-art facility for

three-dimensional structure elucidation (APEX SMART

CCD Single Crystal X-ray Diffractometer) and material

characterization (Bruker D8 Advance Powder X-ray

Diffractometer). Today, the group enjoys a well-

established reputation amongst industry and academia

for its contributions in drug polymorphism and

elucidation of complex molecules (ambiguous through

spectroscopic techniques).

The Center has built up an excellent Institute – Industry

network. From just sample analysis and

characterization in the earlier years, the X-ray

Crystallographic Center has today metamorphosized

into a well-established center for conducting

polymorphism studies of drug molecules towards

Regulatory, IPR and US FDA requirements. A noteworthy

clientele of major pharmaceutical companies viz.,

Merck, Ind-swift, Torrent, Cadila, Lupin, IPCA, USV, Natco,

Dabur, etc., stand testimony to the expertise of the

Center in drug polymorphism studies, product

characterization and quality control issues.

The current research on novel drug molecule towards

structure activity relationship using x-ray

crystallographic studies has fetched the Center a

unique identification in the area of chemical

crystallography. It is noteworthy that several crystal

structures elucidated by the Center has resulted in

publication in leading international journals. The

Center’s own crystallographic research has also

resulted in 23 research papers in international

crystallographic journals.

HPLC/UV GROUP OF ACD

BASIC RESEARCH

Isolation, purification and characterization of

High Resolution ESI - Q TOF Mass Spectrometer

A Close view & Gas Chromatograph - MassSpectrometer (GC-MS) vis Micromass 70-70H

Gas Chromatograph - Mass Spectrometer (GC - MS) AUTOSPEC M

Ion Chromatograph

67

minor impurities and degradation products of

bulk drugs (viz; Astraxanthin, Cyclosporin A,

Cefuroxime Axetil, Bisacodyl etc.) by Prep LC,

FT-IR, MS and NMR.

Enantiomeric resolution studies of chiral drugs

and their synthetic precursors (viz; Mosapride

citrate, Citalopram, doxazosin mesylate,

Rabeprazole, Bicaltamide etc.) by

polysaccharide based chiral stationary phases

(CSPs) using photodiode array and

polarimetric detectors. Comparison of

resolution studies using b-CDs, crownethers

as mobile phase additives by HPLC.

Development and validation of liquid-

chromatographic methods for determination

of process related impurities of Mosapride,

Venalafaxine, doxazosin, Valdecoxib, etoricoxib,

Paracetamol etc.

APPLIED RESEARCH

Development of extraction procedures (i.e.

soxlett and liquid phase) and determination of

Solanesol from tobacco leaves by RP-HPLC.

Development of extraction procedures (i.e.

liquid phase) and residual determination of

Azadirachtin from neem cake oil and tobacco

leaves by RP-HPLC.

NUCLEAR MAGNETIC RESONANCESPECTROSCOPY

The activities of the group involve the study of themolecular structure, conformation and dynamics ofmolecules of interest in chemistry and biology and toprovide efficient and state of the art analytical supportto the scientific projects in the institute and theacademic and industrial users all over the country. IICThas developed expertise in the area of NMRspectroscopy in liquids, liquid crystals and solid stateand magnetic resonance imaging. Study of structuresand conformations of novel molecules and molecularmotions in confined geometries are the niche researchareas of the group.

Research activity: The main emphasis of the research

activity has been on the study of the structure,

conformation and dynamics of peptides,

peptidomimetics and novel organic molecules and

motion of molecules in restricted geometries.

Conformational restrictions, amide bond isosteres,

modifications of native peptide backbone are very often

used in the mimicry of the peptide scaffolds. This group,

designed and carried out extensive structural studies

on peptides containing higher homologues of α- amino

acids, which is a natural extention in the backbone space

of the peptidomimetics and alleviates the

disadvantages of the conventional peptides as

therapeutic agents. The activity in this area

encompasses studies of both linear, cyclic and pseudo

peptides. The capability of NMR spectroscopy to probe

systems at molecular level and providing both structural

and dynamical information was utilized to investigate

liquid crystals, polymers and thin films.

Peptides with β-amino acids: The β-peptides,

oligomers of β-aminoacids, adopt a variety of novel

secondary structures. Mixed 10/12-helices, with

intertwined 10- and 12- membered H-bonds, are unique

to this class of molecules. NMR and CD spectroscopy

were used to show that very small oligomers of a new

family of C-linked carbo β-peptides obtained from C-

linked carbo b-amino acids (Caa) depict right handed

10/12- and 12/10- helices. The observation of such short

helices in tri and tetra peptides was unprecedented.

The unique design uses the concept of “alternating

chirality”. Two epimers of Caa, with “R” and “S” chirality at

the β-carbon, were alternatingly used in the sequence.

In order to relieve the steric strain caused by the bulky

sugar rings, mixed peptides containing Caa and h-Gly, a

β-amino acid with no side chains, were investigated.

These results demonstrated that Caa residues dictate

the conformation of β-h-Gly, leading to the molecules

depicting novel 10/12- and 12/10- left handed mixed

helices in addition to the right handed mixed helices.

14-helix is another interesting class of secondary

structures observed in β-peptides. A new family of

oligomers from cis-β-sugars (Saa) showed well defined

right handed helices. Accommodation of h-Gly in


68


oligomers arranged with alternating Saa and h-Gly

showed that very robust 14-helices can be obtained in

peptides containing as few as three residues. A new

family of 9/11 helices were obtained from a/β- peptides

derived from dipeptide repeat of L-Ala and Caa. The

availability of such a wide variety of short helices is an

important step in creating and designing well defined

tertiary structures, a necessary requirement for having

new family of molecules with the functional properties

like those of biopolymers.

Peptides with γ-amino acids: In addition to the

helices, other ubiquitious class of secondary structures

present in peptides and proteins is a β-hairpin. These

structural elements, specially the segment, that enables

the change in the direction of the peptide chain, play a

Peptides with δ -amino acids: The peptides

containing δ-amino acids, belonging to the family of

conformationally restricted sugar amino acids, were

extensively studied. The O-benzyl protected linear

tetramer of 6-amino-2,5-anhydro-6-deoxy-D-gluconic

acid (Gaa) was shown to take a well defined helical

structure with three repeated β-turns arising due to

the 10- membered H-bonds between the carbonyl of

first Gaa with the amide proton of the third Gaa residue,

Pyrroleamino acid (Paa), which behaves like a restricted

dipeptide isostere of Gly-dehydroalanine, was shown

to take an extended conformation and peptides having

them generate stable β-hairpin with appropriate turn

motif. Cyclic tri-peptide of mannose derived furanoid

sugar amino acids showed a conformation where the

amide and the carboxyl functionalities were on the

opposite side of the ring. Cyclic di peptide of Gaa

resulted in an unusual six membered H-bond between

Gaa NH and neighbouring Gaa C3OH.very important role in the protein function. In an effort

to investigate the stability of such structures, 3 amino-

benzoic acid (Aba), a γ-amino acid, was incorporated in

a designed β-hairpin. It was found that Aba is very well

tolerated in the β-hairpins and does not compromise

their stability. Additionally, it was observed that Aba

permits generation of stable β-hairpins for a variety of

turn motifs, due to dampening of the natural twist of

the strands because of the planar extended geometry

of Aba. A vinylogous – proline (V Pro) motif with a cis

amide bond was used to nucleate a novel 12-membered

turn motif in the designed peptides, which stabilizes

the β-hairpin structure.

69

Other peptides: Several other peptides and pseudo

peptides, both linear and cyclic, were investigated. The

drive for such studies arises from the usual observation

that the conformational restraints arising due to

cyclization may pre-introduce the bioactive

conformation in the molecule. Cyclic peptides

containing heterochiral D-Pro-L-Pro di-peptide template

were shown to take 310

helical structure. Utilizing the

high propensity of proline to have cis amide bonds,

structures of several cyclic peptides with very large

populations with cis amide bonds, which display

interesting turns, were studied.

Novel organic molecules: Molecular structures of

several interesting organic molecules were derived.

Delineation of the molecular structures has helped in

understanding the intricacies of the reaction

mechanisms involved in the chemical reactions. The

unusual formation of benzofused heterocycles in the

aminoglycosidation of C-glycosides was understood

with the help of some detailed and incisisive NMR

experiments, which helped in deciphering the novel

reaction pathway.

NMR studies of soft solids : 129Xe NMR is a versatile

tool to study molecular motions in confined

geometries. 129Xe chemical shifts and relaxation times

were used to investigate the phase transitions in

nematic and smectic liquid crystals. A theoretical model

was developed for understanding the xenon chemical

shifts and was applied to 4-4’-diheptylazoxybenzene.

The monitoring of the hydrophilic-hydrophobic thermal

switching in polymer gels using 129Xe NMR, 1H magnetic

resonance imaging and field-cycling NMR has been

investigated. 1H multiple quantum NMR was used to

study ultra thin lipid and polymer films for

understanding the dynamic heterogeneity and the

surface induced order. Molecular dynamic

heterogeneity of monolayer to submonolayer lecithin

films confined in submicron cylindrical pores were

investigated by magnetization exchange using a

double quantum dipolar filter.

Studies on minerals : These investigations are part of

an active collaboration with Dr. G. Parthasarathy,

National Geophysical Research Institute. The results on

Proterozoic shungite from shungite mines, Russia and

Cretaceous Tertiary boundry layer in Anjar, India, solved

the controversy around the prevalence of fullerenes in

nature. In Anjar samples, the association of fullerenes

with high iridium concentration suggests that they can

be used as marker of an extra terrestrial impact. The

studies resulted in finding the new occurrence of

moganite, a fibrous form of microcrystalline silica, and

ferrous saponite in Deccan flood basalt.

S&T Services : NMR group has provided spectra for

more than 75,000 samples to the users in the laboratory,

in addition, NMR spectra for about 3,700 samples were

run for external users during this period.

ISO QUALITY ASSURANCE CELL

IICT ISO Cell is accredited with ISO-9001-2000. This cell

has catered to the needs of national industry, academia

and other government agencies. It has provided

services to 277 clients who utilized instrumental,

analytical services such as HPLC, XRD,SEM, Paper testing,

NMR, DSC etc. Major clients who utilized services are

Hetero Drugs Ltd. (Hyderabad), Sandoz Pvt. Ltd. (Thane),

AVRA Laboratories Ltd. (Hyderabad), Neuland

Laboratories Ltd. (Medak), Jubilant Organosys Ltd.

(Mysore) Virchow Labs Ltd. (Hyderabad), Nectar

Laboratories Ltd. (Hyderabad), SMS Pharmaceuticals Ltd.

(Medak), APL Research Centre (Hyderabad), Divis

Laboratories Ltd., (Hyderabad), Dr. Reddy’s Laboratories

Ltd. (Bollaram), Biological E.Ltd. (Hyderabad), VIMTA

Laboratories Ltd. (Hyderabad) and Nicholas Piramal

India Ltd. (Hyderabad) and academic institutes such as

University of Hyderabad (Hyderabad) Andhra

University (Visakhapatnam), NIN (Hyderabad) etc.


70

AN INTEGRATED INFORMATION SYSTEMFOR THE CONTROL OF BANCROFTIAN

FILARIASIS IN ANDHRA PRADESH

Filariasis has been estimated that in India about 454

million persons are exposed to the risk of Filariasis

disease. Nearly 28 million persons harbor microfilariae

in blood and about 21 million persons suffer from filarial

disease manifestations.

To control the disease it is necessary to communicate

the disease spectrum to the concerned health officials,

hence the present study has been taken up. The main

objective of the program is to develop the Geographic

Information System for mapping of epidemiological

zones and prioritization of epidemic zones by using

cluster analysis techniques.

Mapping of Endemic Zones: A Geographic Information

System (GIS) is a computer-based tool for mapping and

analyzing things that exist and events that happen on

earth. GIS technology integrates common database

operations such as query and statistical analysis with

the unique visualization and geographic analysis benefit

offered by maps. Four districts from AP i.e., East

Godavari, West Godavari, Karimnagar and Chittor are

selected for the study. Nearly 8,000 blood samples were

collected from 40 villages of three districts i.e., East

Godavari (10), West Godavari (10), Chittoor (10) and

Karimnagar (10) to analyze the parasitic load in the

community. Indoor-resting mosquitoes are being

collected at monthly intervals with the help of

mechanical aspirators (Hausherr’s machine Works, NJ,

USA) during 06:00 to 09:00 hours from the study areas.

Application of Self Organizing Map (SOM) to prioritise

the endemic zone is under progress.

An Integrated rural development programmethrough sericulture at Kandukuru village of RR

Dist., AP

This rural development project has sanctioned under

CSIR’s Rural Action Plan. The project site is located at

Kandukuru village, RR Dist, AP, 32 Kms from IICT,

Hyderabad. This village is a non-traditional sericulture

area. Hence, this project is proposed in Kandukuru village

for the uplifting rural economy of this village.

Farmers of this village are progressive and found to be

more interested towards implementation of sericulture.

Ten thousand mulberry cuttings were planted in 2 acres

of a land and proper irrigation facility has provided.

BIOLOGYBIOLOGYBIOLOGYBIOLOGYBIOLOGY

Management of mulberry plantation at Kandukuru village High yielding VI Mulberry Plantation

71

This project has commenced with specific objectives to

create self employment and income generation for the

rural people. The main objectives of the projects are

establishment of mulberry garden with high yielding

mulberry variety,Implementation of package of practice

for mulberry cultivation, rearing activities of silkworms

for obtaining better cocoon crop and training

programs on various activities in sericulture.

For conducting training on rearing activities, a low cost

model rearing house has been constructed. Nearly 40

farmers (progressive and new) were trained in different

activities on mulberry cultivation and disease and pest

management in sericulture.

CSIR CO-ORDINATED PROJECT

Isolation of collagen from marine sponges

Collagen is a fibrous protein found ubiquitously in all

multicellular animals. It is a particularly rigid and

inextensible extracellular matrix protein that serves as

a major constituent of many connective tissues. Many

pharmaceutical applications are known for collagen, e.g.

shields, injectable dispersions, sponges and

microparticles. Furthermore, collagen is used as a

moisturizer in cosmetic creams. Currently, cattle are

the main source for collagen because of the reasonable

costs for the material and the available knowledge

about its use. The use of bovine originated collagen

has to be reconsidered because of the risks of BSE

(bovine spongiform encephalopathy) and TSE

(transmissible spongiform encephalopathy). It has

been banned by most of the advanced countries and

focused their attention to search for an alternative

origin of suitable collagen. During this process we have

concentrated on marine sponges as a source of collagen

from marine origin. We have identified few potential

candidates and their cell cultures are also initiated by in

vitro methods.

DOD-Sponsored project

Bio-evaluations for newer pesticidal molecules from

marine origin Marine organisms provide a very potential

source for biologically active compounds, and inter

disciplinary approach by biologists and chemists can

pay rich dividends in the exploitation of this source to

derive many active compounds. Usefulness of marine

flora and fauna as anti-bacterial, anti-viral, anti-tumor

and other biologically active agents have been

reported. Less attention has been focused to screen

the marine natural products as pesticidal molecules.

Though the literature indicates that several large

number of novel marine natural products, only a few

have received adequate attention with respect to

pesticidal screening. Past two decades, Biology division

of IICT has evaluated thousands of marine crude extracts

and identified three novel structures as insect growth

regulators (US - Patent has been granted).

Development of alternatives to traditionalacute toxicity tests

World wide, in the last 10 years numerous alternative

toxicological methods have been developed and

proposed in place of standard animal tests for

regulatory safety evaluations. Alternative test methods

are those that incorporate some aspect of replacement,

reduction or refinement of animal use compared to the

corresponding traditional test. Irritation and corrosion

studies for the eye assess the short term effects of

materials which either have a significant potential to

accidentally end up on the eye, or are intended to do

so, for example, pharmaceuticals, personal care

products. These tests have been in existence since the

1030’s. These in vivo methods used rabbits and guinea

pigs for evaluation of materials for their potential to

cause eye irritation. The necessity of using these whole

animal models has been the subject of debate among

scientists and antivivisectionists over the last 20 years.

Hence, with the view of setting up facilities for

alternative toxicological methods for alternatives for

Biology

72

ocular toxicity, work has been initiated. Evaluation of

acute ocular toxicity of some of the pesticides using “in

vivo red cell test system’ has been carried out and will

be sent for publication shortly.

Post Harvest Protection of Maize from Pestsand Diseases in Southern India. TMOP (MAIZE)

It is aimed at developing plant based pesticide to combat

both insect pests as well as fungal pathogens in field

conditions so, that the toxic synthetic pesticides can be

avoided in food products.

Leaves of six indigenous plants were collected and

Soxhlet extracted. The crude extracts were separated

on silica gel column. The resultant chromatographic

fractions as well as crude extracts were bioassayed. In a

fumigation method for insecticidal activity and Y-

olfactometer for repellent activity against the two major

pests of stored maize, Sitophilus oryzae and Rhizopertha

dominica.

The aqueous extracts of the above plants were also

evaluated for their antifungal activity to the toxigenic

strain of Aspergillus flavus. Biochemical studies on

qualitative & quantitative changes of the pests and

fungal infested maize are initiated. About four plant

extracts exhibited excellent insecticidal activity and are

promising for the development of a botanical pesticides

for the use in stored maize. Patents were submitted for

approval.

Advanced Course in Bioinformatics

A unique program on Advanced Course in

Bioinformatics (ACB) was initiated in collaboration with

Centre for Advanced Computing (CDAC) Hyderabad

and JNTU Hyderabad in 2002. The main objective of this

course is to provide an insight into the value of rapid

access to scientific information for education and

research purposes. It is designed in such a way that

student will get an exposure to the various important

modules of bioinformatics and state of art facilities like

opportunity to work on Super computer PARAM 10000

and PARAM PADMA - The program is a Five months

fulltime course consisting of thirteen modules includes

Information Technology, Biostatistics, Genomics &

Proteomics, Structural Biology, Protein folding, Medical

Informatics, Molecular Modeling, Sequence

Analysis, Pharmaco Kinetics & Enzyme Kinetics

and Instrumentation Techniques.

24 Candidates will be admitted into the Advanced

Course in Bioinformatics out of which 6 seats are

reserved for industry sponsored candidates.

Candidates will be admitted only after qualifying

Common Entrance Test (CET). This CET is based on

Computer Fundamentals, Programming Concepts,

Biology Concepts and General Aptitude.

Advanced Course in Bioinformatics - 2004 Batch, Dr. J.S. Yadav,Director is presenting a memento to Dr. Javed Iqbal,

Director,Dr.Reddy Research Foundation

As on date three batches have been completed in the

years 2002-2003,2003-2004,2004-2005, and the present

batch for the academic year 2005-2006 is ongoing. The

students who have completed the course have been

well placed in good industries like Ranbaxy, Reliance,

Jubliant Biosys, Ocimum solutions etc. Some of the

successful students have gone abroad to pursue higher

studies in reputed universities.


73

The Pharmacology Division of IICT is involved in the

basic, applied and technology oriented research. The

pharmacology division caters to the need of various

pharma industries, academic institutions and actively

collaborates with government agencies. The division is

engaged in screening the new chemical entities in the

area of arthrities, diabetes and atherochlorosis,

identified few new leads in the area of arthritis and

diabetes. The basic research is in the area of novel drug

delivery systems concerning to transdermal, liposomal,

nanoparticles and micro spheres etc.. The oral insulin

technology with Vit B12 has been granted US patent

and the commercial negotiations are in progress. There

are other areas of invention, which are with respect to

dendrimer as anti-inflammatory and herbal formulation

for diabetes. The pharmacology division involved in the

CSIR network program – “Animal models and animal

substitute technologies”. The basic infrastructure has

been developed and established a tissue culture

laboratory for screening the compounds. There has

been excellent relations with pharma industry and the

ECF earned by the division is mainly from commercial

organizations. The division has been recognized by Drug

Control Administration of Andhra Pradesh in for

evaluating the quality of the finished products for a

pharma industry. The division has rendered services to

APHMHIDC and AIDS Control Board, Hyderabad and

JIPMER, Pondicherry. Overall about 250 drugs have been

standardized according to IP, BP and USP etc. The

division has qualified GLP and NABL inspector and

implementation of GLP and NABL is in progress.

Technical services provided to Pharma

Industries

Acute oral toxicity study of SMSRC –0401 to M/s

SMS Pharmaceuticals Ltd, Hyderbad

Anti-Inflammatory Activity Of Divi’s Compounds By

Carragennan Induced Rat Paw Edema Model M/s

Divi’s Laboratories Limited,, Hyderabad.

Sub acute toxicity study of wound healing peptide

(GENOPEP) in rats and rabbits, Issar Pharmaceuticals

Pvt Ltd, Hyderabad

Acute Oral Toxicity Of Cefpodoxime Proxetil In Mice

And Rats to M/s APL Research Centre, Hyderabad

Acute Oral Toxicity Study Of Lamivudine In Mice

And Rats M/s APL Research Centre, Hyderabad .

Finished Product evaluation services providedto

(a) APHMHIDC (b) AIDS Control Board (c) 3.Jawaharlal

Institute of Postgraduate Medical Education & Research

Pharmaceutical screening of Herbalformulation for

(a) Immunomodulatory activity (b) Preclinical Toxicity

of Bhasmas provided to Central Council For Research

in Ayurveda & Siddha, Deptt. Of Ayush, Ministry of Health

& Family Welfare, Govt of. India, New Delhi.

PHARMACOLOGYPHARMACOLOGYPHARMACOLOGYPHARMACOLOGYPHARMACOLOGY

Automatic Tissue Processor

74

ENGINEERING INTENSIVE CHEMICALPROCESSES AND SEPARATIONS

The group aims at the development of engineeringintensive and eco-friendly processes of commercial orstrategic importance, utilizing the expertise of themembers in the specialised subjects such as: reactionengineering and process development, processdynamics and control, properties evaluation andmembrane separations.

REACTION ENGINEERING AND PROCESSDEVELOPMENT

APPLIED RESEARCH

Mononitrotoluenes

Pilot plant scale process for the continuous optimalproduction of para-nitrotoluene using solid acidcatalyst, at 2-4 kg/hr of mixed monitrotoluenes isdeveloped and ready for demonstration to sponsor,

Xylose and Xylotol

In view of their importance as substitutes for sugar,process development activity for the production ofXylose and Xyltol have been initiated. The work aims atthe production of Xylose or Xyletol from agriculturalwaste products. The initial results are encouraging.Studies aiming at the optimization of process conditionsare in progress. Scale-up and further studies will betaken up on sponsorship.

BASIC RESEARCH

As a corrolary to the problems encountered during theon going projects, as well as the academic interests basicstudies in Chemical Reaction Engineering on thefollowing topics has been initiated.

Micro Reactor Technology, with the primaryobjective of setting-up of a general purpose Micro-reactor System followed by experimentation onselected reactions.

Studies of Multiphase Reactions with SpecialReference to the Formation of Ketazine(anintermediate in the eco-friendely process forhydrazine).

Regio-selective catalytic Vapor Phase Alkylation ofAniline using Clays

Selective Vapor Phase Ethylation using Zeolites

Bio-reactors for Cyanohydrin Production withNovel Porous Vessel Bio-reactor for reactions withImmobilized Enzymes and Microbial Cells

Microbial Oxidation of Alkanes

PROCESS DYNAMICS AND CONTROL

APPLIED RESEARCH

Novel methods have been developed in the fields ofadvanced process control and on-line optimization, andtheir performances are evaluated through dynamicsimulation involving transient and continuous timedomain chemical processes.

Advanced Real-Time Control Technology for BatchReactors and Technology Upgradation

Advanced Real-time Process Control Technology

CCCCCHEMICALHEMICALHEMICALHEMICALHEMICAL ENGINEERING SCIENCESENGINEERING SCIENCESENGINEERING SCIENCESENGINEERING SCIENCESENGINEERING SCIENCES

Titanium Dioxide

Process for the production of Titanium Dioxide has been

taken up under the task force projects for Globally

Competitive Technologies. Chlorine recovery from

hydrochloric acid has been chosen for the first phase of

the investigation. Relevant literature survey has been

completed and good progress has been made towards:

Procurement of Raw Materials and Reactor Fabrication

and Set-up. Some preliminary experiments have been

conducted making use of a glass reactor and the

essential equipments are being procured.

Mononitrotoluene pilot plant

75

for Batch Reactors – a project sponsored byDepartment of Science and Technology,Government of India has been successfullycompleted and final report submitted.

Autotuning PID control has been established forNMSM formation reaction and the technology isdemonstrated to SMS pharmaceuticals Ltd,Hyderabad.

Real-time process control technology has beendeveloped for a batch reactor system by setting up anexperimental batch reactor and connecting it to apersonal computer for on-line data acquisition andcontrol. Optimal operating conditions have beenestablished and automated operation has led to higheryields and consistent product quality in both theindustrial reactions.

Automated solid potassium hydroxide feeding with thehelp of a fabricated screw feeder arrangement coupledwith automatic control of temperature with the help ofcoolant flow as the manipulated input has beendemonstrated to SMS Pharma Industry that the yieldhas improved from 50 to 65%.

Streamlining and minimizing the number oftemperature set point changes, reduction in batch timefrom 12 to 10 hours, modification of the feeding strategyfrom both solid and liquid feeds to only liquid feedingstrategy, improvement in yield from 48 to 55% are someof the main achievements in NMSM formation reaction.Real-time Control technology has been demonstratedto SMS Pharmaceuticals Ltd. for automation of solidfeed and advanced control of temperature for betterand consistent yield in dipotassium formation reaction,which is the first step in the preparation of the drug,ranitidine. Process is available for release to other clientson sponsorship.

Artificial Intelligence Based Tools for ProcessModeling, Optimization and Control

A new data driven approach has been proposed formodeling and trajectory optimization of a batch or asemi-batch process. The effectiveness of the proposedArtificial Neural Net(ANN) based modeling and trajectory

optimization scheme is demonstrated using simulationstudies on a benchmark MIMO semi-batch processreported in the literature. The results of this work areincluded in a research paper published in Industrial andEngineering Chemistry Research.

EKF(Extended Kalman Filter) is proposed as a controllerfor control estimation by incorporating different levelsof process knowledge for chemical engineering systems.The concept of Extended Kalman Filter controller isfurther extended to incorporate time-delaycompensation. New predictive and optimal controlformulations have also been proposed using the EKF.Part of the work is also included in a technical papercommunicated to CHEMCON 2004, Dec. 27-30, 2004.

Two data-driven model based trajectory trackingcontrol algorithms have been proposed using input-output data-driven models (linear-in-parameters timeseries models with time-varying parameters andnonlinear Artificial Neural Networks) within a GenericModel Control(GMC) framework, and are evaluated byapplication to a multi-product semi-batch polymerizat-ion temperature control challenge problem and amultivariable semi-batch reactor problem. Theperformance of the EKF based GMC algorithm iscompared to that of an auto-tuned PI controller fortemperature control of the exothermic batch reactorinvolving formation of hexyl monoester of maleic acid.The results of this work are included in a technical paperat CHEMCON 2004, Dec. 27-30, 2004.

Off-line optimal control approaches have been exploredfor a ternary batch distillation column with slop recyclefor separation of a mixture of cyclohexane, n-heptaneand toluene using Pontryagin’s Maximum Principle andControl Vector Parameterization. The study has beenfurther extended to evolve on-line optimal control ofbatch distillation.

Plant-Wide Control Design Procedure

The main objectives for this project recently initiatedare - to design a plant-wide control structure based ondifferential geometric approach, and to apply theproposed method to Tennessee Eastman ChallengeProblem. The study has established that incorporation

Chemical Engineering Sciences

76


of interaction for control can result in considerableimprovement in control performance.

Facility Set-up

Experimental Batch Reactor real-time control systemwith PC based on-line data acquisition & control withseveral accessories including a screw feeder forautomatic solid-feeding and remote-operated liquidfeed and cooling water pumps.

BASIC RESEARCH

Heat Release Estimator Based GloballyLinearizing Control of a Chemical Reactor

Chemical reactors, especially batch reactors occupy aspecial position in chemical processing industries.Realizing the advantages offered by the advancedcontrollers, various model based controllers involvingrigorous process models have been reported for batchreactors. Although rigorous process model is quiteuseful in deriving efficient controllers, developing andvalidating rigorous models involving reactionmechanisms and reaction kinetics require considerabletime and effort. Therefore, control strategies based onmodels that avoid reaction kinetics and instantaneouscomposition measurements, but preserve therigouressness by instantaneous estimation ofunknown information are quite beneficial. In this study,an energy model based globally linearizing controller(EMBGLC) supported by a deterministic filter ispresented for temperature control of an exothermicbatch reactor. The deterministic filter is used to estimatethe rate of heat release required for the controller. Theresults of the EMBGLC supported by the deterministicfilter are compared with the EMBGLC based on otherdeterministic heat release estimators including a directenergy balance and a kinetic rate expression. The resultsshow that the EMBGLC based on deterministic filterprovides better performance for the temperaturecontrol of the exothermic batch chemical reactor.[Indian Journal of Chemical Technology, 10, 539-544(2003)]

Fuzzy Adaptive Controller for pH

Control of pH Processes is very difficult due to

nonlinear dynamics, high sensitivity at the neutralpoint, and changes in the concentrations of known orunknown chemical species. In this study, a dynamicfuzzy adaptive controller (DFAC) with a new inferencemechanism is proposed and applied for the control ofnonlinear pH processes. The DFAC consists of a low levelbasic control phase with a minimum rule base and ahigh level dynamic learning phase with an updatingmechanism to interact and modify the control rulebase. The DFAC can self adjust its fuzzy control rulesusing information from the process during on-linecontrol and create new fuzzy control rules or modifythe present control rules using its learning capabilityfrom past control trends. The controller is evaluated byapplying it to a weak acid-strong base pH process withinput disturbances and another pH process that involvechanges in acidic/buffering streams. The results of theDFAC with the new inference mechanism is comparedwith the known inference mechanisms, the fuzzycontroller, the conventional PI controller and also withthe adaptive PID controller. The proposed DFACprovides better performance for setpoint tracking ofthe pH and rejection of load disturbances and bufferingaffects.[Chemical Engineering Communications, 191,1564-1588 (2004)]

Data Driven Modeling and Optimization ofSemibatch Reactors Using Artificial NeuralNetworks

In this study, a data driven approach has been proposedfor modeling and trajectory optimization of a batch ora semibatch process. The approach is based onparametrization of input and output trajectories asfinite dimensional vectors using orthonormalpolynomials. Using input/output trajectory informationavailable in historical data bases, an artificial neuralnetwork (ANN) based model has been developed forcapturing the dynamics of semibatch processesoperated over a fixed interval of time. The parametrizedinput trajectories, initial states, and process parametersare considered inputs to the ANN model, which predictsoutputs in terms of fourier coefficients. The resultingalgebraic model is used to formulate an optimal controlproblem, which can be solved using conventionalnonlinear programming techniques to generate open-loop optimal input policies. The proposed ANN based

77

modeling and trajectory optimization scheme isevaluated through simulation studies using a multipleinput-multiple output semibatch process. The resultsshow the effectiveness of the proposed scheme fortrajectory optimization of semibatch processes.[Industrial & Engineering Chemistry Research, 43, 7539-7551 (2004)]

Dynamic Recurrent Radial Basis FunctionNetwork Model Predictive Control ofUnstable Nonlinear Processes.

Model predictive control (MPC) is known to be a verypowerful control strategy for a variety of chemical andbiochemical processes. In this study, A multistep modelpredictive control strategy based on dynamicallyrecurrent radial basis function networks is proposedfor single-input single-output (SISO) control of uncertainnonlinear processes. The control system consists of twoautomatically configured radial basis function networks,a trained network representing the plant model and anetwork with on-line learning to function as controller.The automatic configuration and learning of thenetworks is carried out by using a hierarchically selforganizing learning algorithm. This control strategy isstructurally simple and computationally efficient sincea single output node of each radial basis functionnetwork (RBFN) is configured to provide multisteppredictions for plant output and controller. Theperformance of the proposed radial basis functionnetwork model predictive control(RBFNMPC) strategyis evaluated by applying to two unstable nonlinearchemical processes, a chemical reactor and abiochemical reactor, and also a stable polymerizationreactor. Further, the results of the RBFNMPC is comparedwith similar RBFN model based control strategies andalso with well tuned PID/PI controller. The results showthe better performance of the proposed RBFNMPC forthe control of open-loop unstable nonlinear processesthat exhibit multiple steady state behavior. [ChemicalEngineering Science, 60, 6717-6731(2005)]

PROPERTIES EVALUATION

Measurement of thermophysical properties to cater tothe requirements of in-house or outside users and ofacademic interest, employing the available facilities is

continued. During the period, data on - density, viscosityand specific heat of liquids, solid-liquid phase transitions,specific heat and thermal conductivity of solids - of over125 samples at the conditions of interest(mostly ofoutside users) has been provided. Results of the work,carried out on the basis of academic interest(mostly onisobaric vapor-liquid equilibria and excess enthalpies ofbinay liquid mixtures) at ambient pressure, have beenpublished in international journals.

Monographs

Preparation of monographs on thermophysicalproperties of gases, liquids and mixtures has beeninitiated in association with other interested colleagues.First draft of the manuscript of a book “Viscosity ofLiquids” incorporating methods of: measurement,correlation and prediction and available exprimentaldata is ready and efforts are on to complete it and sendit to the publisher.

Aiming at improvement to the activities, the followingbasic studies have been initiated with the help ofresearch fellows.

PVT Relations of Fluids

Vapor-Liquid Equilibria of Selected BinaryMixtures.

MEMBRANE SEPARATIONS

This activity is centred round the development andtesting of membrane based separation techniques forpractically important mixture systems. The studiesencompass both liquid and gas mixture systemsinvolving ions and radicles and their transfer. Thefollowing important projects have been completed.

Installation of Pervaporation, Gas Separation andElectrodialysis Membrane Systems for Centre ofExcellence in Polymer Science, Karnatak University,Dharwad

Installation of Electrodialysis Pilot Plant forDemineralization of Milk for PermionicsMembranes Private Limited, Vadodara

Development of Membrane Technology for NaturalGas Separation for ONGC (DSIR-PATSER)


78


Extraction of Impurity-Free Sodium ThiocyanateAqueous Solution of Nonofiltration forConsolidared Fibres and Chemicals(CFCL), Haldia

To strengthen their knowledge base, the members ofthe group initiated systematic basic studies on:

Membrane Technology for Purification of naturalgas, and

Synthesis and Characterization of ProtonConducting Polymer Membranes.

CHEMICAL PLANT DESIGN AND ENGINEERING

This group is engaged in upscaling processes developedby R&D divisions of IICT i.e. drugs, agrochemicals, bulkorganics, catalysis etc., and collects design data forproviding basic design for commercial plants

Commercial software packages like ASPEN PLUS, B-JACas well as the software developed in-house are nowused in this activity. Property data bank incorporatedinto Aspen plus is of great help and reduces searchtime considerably. Modern CAD packages areextensively used for synthesis of process flow sheets,equipment specifications plant lay out drawings, P&Idiagrams, pipeline routing diagrams and single lineelectrical diagrams and other related items. Majoractivities of this group is given below:

Plant Design and Basic Engineering

Synthetic Aviation Lubricants:

On the basis of data obtained on laboratory scaleexperiments conduced by Lipid Science and Technologydivision of IICT, a 5kg/batch esterification reaction

system has been designed, fabricated andcommissioned to prepare product samples of 5 kgbatch and also to collect data for the design of the pilotplant. The base oils meeting the specifications wereshort listed for formulation and testing at consortiumpartner. As per the micro plan four samples of SVS.1base oil and one sample of SVS.2 base oil were sent toconsortium partner for further evaluation, formulationand testing. The SVS.1 samples were meeting thespecifications of MILPRF 23699F. SVS.2 sample wasmeeting the specifications as per the requirements ofconsortium partner. Design of pilot plant of capacity75-100 kg/batch has been initiated. Further work inoptimizing the process parameters on 5-kg scale is inprogress.

Biodiesel

Process development work for bio diesel from high FFAoils and acid oils has been carried out in collaboration

with lipid science & technology group. A two-stepprocess of esterification of FFA/ trans-esterification ofglycerides (Jatropha) has been carried out on 1 kg per

batch scale. This process has been scaled up to 50 kg oilper batch and the know-how is available for commercialexploitation. The work on similar line using karanja oil is

in progress. Sponsored by TMOP & M ministry ofagriculture govt. of India, New-Delhi.

Hydroxyethyl Cellulose: A bench scale process forHEC was developed. The batch size was 20 grams.

A know-how report has been prepared. Furtherwork to develop a dry process for PIL is in progress.(sponserer M/s Pidilite Industries Ltd., (PIL) Mumbai)

Vinyl Chloride Monomer: Designed a continuouslaboratory scale reactor setup for the preparationof vinyl chloride monomer by the oxychlorination

of ethane. The rector setup is to be operated with10gram catalyst. A tender document has beenprepared for floating tender for the fabrication,

erection and commissioning of setup on a turnkeybasis. This is a part of the project “Functionalizationof alkanes” awarded by CSIR to IICT under New

Millennium Indian Technology Leadership Initiative(NMITLI). Work is in progress.

Membrane separation bench scale unit

79

Pyrazinamide: Engineering design report for 500TPA pyrazinamide plant for SPIC Tuticorine, chennai,have been prepared & submitted to DSIR. Project iscompleted.

Government Opium & Alkaloids works: Detailedreports on the following processes were preparedand submitted to GOAW.

a) The validation of process studies on theextraction of alkaloids from opium..

b) The improvement of the efficiency of the solventrecovery in the plant.

Tetra Bromo Bis Phenol - A (TBBA): Thecontinuous pilot plant for the manufacture of TBBA50kg/hr was erected and commissionedsuccessfully at Karwar. The process parameterswere optimized by operating the pilot plantcontinuously. Further some more bench scaleexperiments were conducted for recovery of DCEsolvent and to generate the necessary data forreducing the consumption of sodium sulphite inmulti stage counter current extraction system. Thedata from these experiments will be useful inimproving the economics of the process. The pilotplant was successfully demonstrated, guaranteeruns were completed. The product from the pilotplant found to meet all the specifications. Thereparation of DPR for 10000 TPA commercial plantis in progress for evaluation of economic feasibilityfor continuous as well as batch process. Sponsoredby M/s Solaris Chemicals Ltd, Karwar, Karnataka

Natural Products Extraction Pilot plant:

This project is aimed at standardization of theprocess and setting up of the solid liquid extractionsystem facility at Aryavaidyasala, Kottakkal as a partof the on going DST-IICT-AVS joint program. A five-stage counter current continuous extractionsystem is designed, fabricated and erected atAryavaidyasala, Kotakkal. Mechanical commission-ing was completed successfully. Experiments wereconducted to optimize the process parameters viz,time of extraction, temperature, and particle size,water to solid ratio.

Process Improvement for “Aspirin Plant” ofM/s Andhra Sugars Limited, Tanuku, AP

Presently M/s Andhra Sugars are manufacturing Aspirin,a basic drug and exporting as per FDA regulations ofUSA. However, the consumption of raw materials isobserved to be on the higher side, when compared withthe International Manufacturing Practices. IICT taken upthe assignment for looking into the process/manufacturing details and workout methodologies toimprove the conversions/yields/recovery, first in thelaboratory level. The pilot level experiments shall beconducted at Andhra Sugars Limited and finallyimplemented in the commercial plant, under theguidance/consultancy of IICT. IICT completed thelaboratory experiments successfully and designs of pilotplant equipment is in progress.

PROCESS MODELLING AND SIMULATION

IICT has been active in the area of process modelingand simulation of chemical process plants for the lasttwo and half decades. The institute has undertakenseveral process improvement optimization studies ofchemical process plants through modeling andsimulation and development of simulation/designsoftware for various unit operations.

Design and Supply of Gas Cracker Pilot Plant

This project has been awarded by M/s Gas Authority ofIndia Ltd., (GAIL) for the “Design and Supply of GasCracker Pilot Plant” of 5 kg/hr capacity for thermalcracking of ethane or ethane/propane mixture toethylene. Flow sheet for the pilot plant is developed

GAIL Pilot Plant


80

and the equipment such as the furnace, reactor coilsheat exchangers are designed along with the pipingand instrumentation. The tender document for the skidmounted pilot plant is prepared, and the contract forthe fabrication, supply and erection of the pilot planthas been awarded to M/s Xytel India Pvt. Ltd. Suitableonline gas analyzers for product gas analysis duringcracking and decoking are procured. Risk analysis ofthis pilot plant is done to identify hazards and suitabledesign modifications are made. The pilot plant iscontrolled by a PC/PLC system. The pilot plant is erectedand commissioned and it is working satisfactorily. Thisis a first of its kind assignment undertaken by IICT.

PROCESS SAFETY CENTRE

The Process Safety Centre (PROSAC) developed

expertise in the areas of Hazard analysis, Risk

assessment and Disaster management programs.

PROSAC offers its expertise and services to various

chemical, petrochemical and agrochemical industries.

The chemical plant industrial activities associated with

processing, storage and transportation of hazardous

chemicals where fire, explosion and toxic hazards are

likely to take place and reasonable risk to society exists

are studied in detail. The project taken up and

successfully completed by this group is given in

Annexure.

IICT Process Safety Center is equipped with the following

test facilities and provides technological services on

payment basis.

Dust Explosion Tests

Laboratory Apparatus of the type KSEP 20L is used for

the determination of Explosion Indices of Combustible

Dusts and gases.

Ignition Test for airborne Dust BAM-Oven

This test is designed to determine the ignition

temperature of airborne dust on a hot surface (e.g. spray

drier)

Test for Exothermic Reaction in an open cupLutolf Oven Type MP-4

This test is designed to determine the lowest

temperature at which a substance shows an exothermic

reaction under defined oxygen-lean conditions. With

this test, the maximum permissible temperature of the

heating medium can be derived.

TRAINING PROGRAMMES IN PROSAC

PROSAC is organizing the training programmes to

various chemical and petrochemical industries in the

field of Safety, Hazard and Risk analysis. The Process

Safety Centre successfully completed more than 100

Hazard Analysis and Risk Assessment assignment in

2003-2005 period. In addition about 40 to 50 samples of

various chemicals were analyzed for the hazardous

properties, such as flash points, flammable limits, auto

ignition, temperatures and pressure waves generated

when explosion takes place.

Presently Process Safety Centre is jointly working in

collaboration with Institute of Engineering and Ocean

Technology (IEOT) – ONGC for three assignments related

to soft wave and data-base development. They are:

1. Reliability of safety system in Off-shore platform.

2. Failure frequency data base.

3. Toxic gas dispersion models for off-shore plant

forms

The nature of work is undertaken first of its kind in

India and International application, specially in the Off-

shore operations is expected.

A view of ONGC off-shore platform


81

APPLIED RESEARCH

Detailed Engineering Designs for pilotplants

For Nitration of Toluene for M/s Vasant Chemicals Ltd

and M/s Deepak Nitrates; Pyrazinamide for SPIC;

Benzaldehyde for Vinati Organics Ltd; HFC-134a for M/s

Navin Flourines; TBBA for M./s BILT Chemicals Ltd,

Hyderabad; RWOOD Pilot Plant for RRL-Bhopal includes

engineering support in form of designs, inspection,

testing and commissioning of equipment and related

machinery; Base Frame and Machine Mounted turbine

and compressor piping 3D layouts consultancy work

carried out for BHEL, Hyderabad. Setting-up of a pilot

and testing facility for preparing and testing of

lubricants for aviation industry

Detail Engineering Design for CommercialPlants

The process know-how for the extraction of natural

colors from turmeric; chilli and annato seeds was

developed and demonstrated by Central Food

Technological Research Institute (CFTRI), Mysore.

Detailed Engineering Designs for the integrated

commercial plant were provided by IICT. The integrated

commercial plant is designed to have all the

infrastructure facilities for processing of 1.0TPD of raw

material turmeric, chilli and annato separately in three

different sections at same time.

Safety Assignments with PROSAC

Studies on Vulnerability and Risk Assessment of

Transportation of hazardous substances in the

State of Andhra Pradesh - A survey was done on

NH9 &7 to acquire information related to accidents

involving tankers carrying hazardous chemicals

and to collect information on the infrastructure

facilities available. The database was further used

in carrying out the QRA studies.

HAZOP studies were carried out for Rayalseema

Alkalis Plant Complex, Kurnool; Butadiene storage

facility and Reactor for M/s Andhra Sugars Pvt Ltd.,

Tanuku; UDMH process for M/s Andhra Sugars

Limited, Tanuku; Storage facility of POL products

and pipeline Transport POL products by pipeline

from Mangalore refinery to Bangalore for M/s

PETRONET, Mangalore

Safety Audit was carried out for M/s RALCHEM Pvt

Ltd, Hyderabad; Rayalseema Alkalis and allied

Chemicals Plant Complex, Kurnool and Cherlapally

POL Products Depot, Hyderabad

Quantitative Risk Assessment studies of the field

rooms for M/s HPCL Refinery Visakhapatnam-

What-if Analysis was carried out for PRU, DHDS,

Hydrogen storage and SRU facilities to identify

hazards associated in the process. As part of QRA

study for field rooms –most credible hazardous

scenarios were identified in all the four units.

MECHANICAL DESIGN AND ENGINEERINGMECHANICAL DESIGN AND ENGINEERINGMECHANICAL DESIGN AND ENGINEERINGMECHANICAL DESIGN AND ENGINEERINGMECHANICAL DESIGN AND ENGINEERING

Natural Color Extraction Plant for M/s KCP Biotech Private Limited, Hyderabad

82

Consequence analysis and determination of

individual and societal risk values were found out.

Development of failure frequency database: for M/

s Institute of Engineering and Ocean Technology,

Mumbai.

Rain Erosion Facility

The ‘rain erosion test rig’ setup is the first of its kind

in the country to test the rain erosion

characteristics of paints developed and applied on

the high speed rotor blades of the aircraft. The

paints such as for the wings /blade of aircraft have

to conform to international standards such as MIL-

C-83231A. Hence it is mandatory for the paint

manufacturers to get erosion test clearance for

their paints by well-established certifying agencies.

This rain erosion test has to be invariably

conducted before the well-established qualifying

& Certifying agencies of the Ministry of Defence like

M/s RCMA, Hyderabad. Considering the national

importance in developing a suitable rain erosion

resistant paint many clients both private and

government including defense agencies such as

KCMA, Hyderabad tested the paints.

The paint samples are to be evaluated for 1" Rainfall

conditions with 2mm diameter rain droplets falling

continuously on the paint samples and when the

paint samples are subjected to sustained wind

simulation speed of 500 miles per hour. Presently,

the test rig has achieved 350 mile per hour wind

simulation at 1’’rainfall conditions with 2 mm

droplets. The test rig is successfully demonstrated

to the inspecting agencies of M/s Aeronautical

Development Agency, Bangalore.

Number of IICT paint samples were tested and paints

with better rain erosion qualities have been developed.

The test Rig was also successfully demonstrated to

evaluate the rain erosion characteristics of indigenous

paints developed by private and defense clients

recently.

DESIGN OF SPECIAL EQUIPMENT

Rota Disc Dryer/Cooler Special Equipment

The equipment consists of a centraly mounted

rotating screw type mechanism with many screw

type leaves arranged in concentric fashion with a

provision to circulate fluids through inner

periphery of the screw type mechanism.The

roating screw mechanism is also provided with a

fluid circulating jacket.The process solids while in

the screw are being pushed forward by means of

pushers clamped to the individual screw type

leaves while hot/cold fluid is circulated in the inner

and outer jackect of the screw type mechanism to

enable the process solids to be heated /cooled

while being processed in the unit.

The screw type mechanism assembly is powered

by means of an electrical 3HP motor provided with

a hand operated variable speed mechanism drive

to enable to increase/reduce the speed of the screw

type mechanism.Rotary fluid joints help in

successfully circulating fluids from the stationary

pipe to the constantly rotating inner jacket of screw

type mechanism. The unit can be ideally operated

for process solids heating , cooling and drying

Paint testing Unit


83

operations. This can also be used for thermal

stabilisation of Rice-Bran

Project planning activity

Project Planning and monitoring activity was carried

for a number of projects by using a method called ZOPP,

which stands for “Objectives Oriented Project Planning”.

This method emphasizes participation of all concerned

agencies to evolve in detail, a project planning matrix

(PPM) followed by a comprehensive plan of operations

(POP), which is the micro – schedule of the project. This

is followed by a detailed method of monitoring and

evaluation of the process of the project.

The project planning using the above method was

carried out for the following projects

A multi-institutional project – NINE plus that stands

for NGRI, IICT, NRSA, EPTRI and other agencies. This

project aims to study the “Carrying Capacity”, of

Visakhapatnam region”.

Biotechnology incubation center (BTIC) project

aims to establish a state of the art facility for

incubating biotechnologies and to provide world-

class facilities to different clients and designing to

upscale their bioprocesses.

BASIC RESEARCH

Simulation and modeling through virtual

reality with special emphasis on chemical

lab safety and hazards

Most of the accidents that occur in chemical lab and

chemistry are due to lack of knowledge / practice of

safety principles. Regular and periodical ‘Hands on “

refreshment training course to the staff is likely to

reduce these accidents drastically. However, organizing

training programs can be tedious and time consuming

and expensive to the organizations / Institutions /

Industry.

Use of computerized Virtual Reality (VR) immersions

can come to the rescue of this situation through the

development of training simulators. Virtual Reality (VR)

is cutting edge technology that allows us to step

through the computer screen into a three dimensional,

interactive environment. Virtual Reality provides an

opportunity to the user to get immersed totally in the

required / suitable scenario and offer spontaneous reflex

actions to the computer simulated scenes. Besides

graphic scenes through suitable display devices a

physical interface is possible in VR to represent /

simulate physical reflexes of users.

Transverse vibrations of multiply bellows

expansion joint elastically restrained

against rotation

Dynamic aspects of single and multiply bellows with

elastically restrained ends and under rotatory inertia

were studied. The effect of rotational restraints and

internal pressure loading on response of such bellows

configuration is attempted. The exact coupled response

obtained is compared with previous works. Two cases

are considered- bellows having same material and

different materials for plies. An attempt has been made

to derive and establish expressions that are simple and

compatible in computing the natural frequency and

mode shapes of bellows. The “Rayleigh Quotient”

method is also used for this purpose. (Journal of Thin

Walled Structures, 42(2004) 415-426, Elsevier Applied

Science Publishers, Great Britain)

Mechanical Design and Engineering

84

The IICT Computer Centre undertakes application

software development in areas of scientific importance

to institutional research programmes, besides

providing scientific inputs based on computer aided

techniques to ongoing R&D projects and conducting

training programmes in advanced computer

programming.

Ranking of Indian Coals by Fuzzy MultiAttribute Decision Making(FMADM)

Coal ranking problem is modeled as fuzzy multi

attribute decision making problem. Proximate analysis

of coal is taken as basis. Saaty Analytic Hierarchy Process

(AHP) was employed to come out with importance

ratings for 4 coal quality variables viz. Fixed Carbon,

Volatile Matter Moisture Content & Ash Content. Then

modified Yager’s FMADM model is invoked to come

out with ratings for different cooking & non-cooking

coalfields in India. The study was conducted for three

memberships functions and 4 aggregators. In

conclusions, the modified FMADM model yielded better

ratings for coal fields than the ones given by factor

analysis study.

Fuzzy Rule Based Classification withFeature Selector and Modified ThresholdAccepting

This study highlights the paramount importance of

feature selection in the context of fuzzy rule based

classifications. Feature selection is taken care of by a

software Feature Selector. Then the modified fuzzy rule

based classifier is developed and invoked for classificat-

ion task. Later the modified threshold accepting

algorithm is developed and invoked to solve the result-

ing combinatorial optimization problem with 2

objective functions to maximize classification power

and to minimize the size of the rule base. The efficacy of

the model is demonstrated on wine classification and

Wisconsin breast cancer problems yielding very good

results.

Principal Component Analysis and FuzzyRule Based Classification.

For the first time, Principal Component Analysis wascombined with fuzzy rule based classification. PCA was

used a feature selecting module. Then the modified fuzzyrule based classifier invoked. The entire software is testedfor its efficacy on wine and Wisconsin breast cancer

problems yielding good results.

Fuzzy Global Optimization of ComplexSystem Reliability

The optimization problem of complex system reliability

is modeled in a fuzzy environment. The resulting crispversions are solved by threshold accepting algorithm.The study is conducted for 6 different types of

aggregators. The study yielded more efficient solutionscompared to the ones conducted in the single objectiveenvironment.

Prediction of Treatment Concentrations forthe Reduction of COD of the Effluents ofPesticide Plant by LOGIT Models.

The necessity of reducing the COD contents of the

effluents of the pesticide plant to acceptable limitsbefore releasing it to the environment is very muchessential. Treatment methods for reducing COD values

are developed and the reduced COD values for variousconcentrations of activated coconut shell (ACC) areevaluated experimentally. A novel statistical model

called logit model is developed for establishing therelationship between ACC concentrations andpercentage COD reduction. The model was found to

give very accurate results for predicting ACCconcentration requirements for the reduction of CODvalues by 50,60,70,80,90,95 and even 99% of the original

COD values.

Correlations Among Physico-ChemicalProperties of Effluents of Various ChemicalProcess Industries.

Very good correlations were observed among thephysico-chemical properties like pH, conductivity(COND), Total Dissolved Solids (TDS), and Chemical

COMPUTER CENTRECOMPUTER CENTRECOMPUTER CENTRECOMPUTER CENTRECOMPUTER CENTRE

85

Oxygen Demand (COD) for the effluents of variouschemical process industries and IICT processes. Thesecorrelations are very helpful in understanding the

associations among the physico-chemical propertiesof effluents. Also, good prediction equations have beendeveloped for predicting COD in terms of pH, COD and

TDS.

Software Development

Several web sites were developed for various seminarsand MIS Applications.

Data Mining

A pilot study was carried out successfully for the datasupplied by M/s Satyam Computers Ltd. The datapertaining to CD buyers information like age,

education, occupation, race, relation, sex, working class,marital status, etc. was analyzed. The objective of thisstudy was: 1) to develop a predictive model for the

above data (ii) to identify the potential CD buyers. The

data mining techniques like fuzzy rule basedclassification, neural nets and multivariate statistical

models, were applied to analyze the data.

The Computer Centre has developed new expertise inthe following multi disciplinary area:

� Fuzzy Computing

Fuzzy cluster analysis, Fuzzy rule based systems

for pattern classification

� Neuro Computing

ANN & its variants for forecasting & patternclassification, neuro-fuzzy hybrids

� Evolutionary Computing

Global optimization meta heuristics, combinatorial

optimization, Multi objective optimization.

� Statistical Modelling

MLR Techniques, Univariate Methods, Data ReductionTechniques, Time Series Models, Pattern Identification

and Clustering.

Computer Centre

86

BASIC RESEARCH

Hydrogen Production from AnaerobicProcess

Biohydrogen production through anaerobicfermentation using chemical wastewater wassuccessfully achieved on a lab scale reactor. Reactorconfiguration, inoculum pretreatment, startupprocedure, co-substrate addition, nutrient composition,etc were optimized for effective hydrogen production.Suspended growth and biofilm configured systemswere designed and operated in periodic discontinuousmode for the production of hydrogen using compositechemical and bulk drug wastewater. By way of processoptimization, effective hydrogen yield was achieved inboth the configured systems however, biofilmconfigured system showed superior performance.

Anaerobic Process Optimization byDynamic Taguchi DOE Methodology

Taguchi robust experimental design methodology wasapplied on dynamic anaerobic process treating complexwastewater by anaerobic sequencing batch biofilmreactor (AnSBBR). For optimizing the process and toevaluate the influence of different factors on the processthe uncontrollable (noise) factors were considered.Taguchi methodology adopting dynamic approach isapplied for the first time for studying anaerobic processevaluation and process optimization. In theexperimental design, five controllable factors i.e., organicloading rate (OLR), inlet pH, biodegradability (BOD/CODratio), temperature and sulfate concentration, alongwith the two uncontrollable (noise) factors viz., volatilefatty acids (VFA) and alkalinity at two levels wereconsidered for optimization of the anaerobic system.Thirty two anaerobic experiments were conducted withdifferent combination of factors and the resultsobtained in terms of substrate degradation rates wereprocessed in Qualitek-4 software to study the maineffect of individual factors, interaction between theindividual factors, signal to noise (S/N) ratio analysisand finally, attempts were made to achieve theoptimum conditions. Considering the obtainedoptimum factors, further validation experiments were

carried out, which showed enhanced processperformance (3.04 Kg COD/m3-day from 1.99 Kg COD/m3-day) accounting for 52.13% improvement with theoptimized process conditions. The proposed methodfacilitated a systematic mathematical approach tounderstand the complex multi-species manifestedanaerobic process treating complex chemicalwastewater by considering the uncontrollable factors.

Production of Enzymes

Laccase Production by submerged fermentation:Production of laccase using pleurotus ostreaus 1804was studied under various experimental conditions.Among the carbon sources studied, glucose resultedin higher laccase yield whereas dextran and glycerolsupplemented broth showed relatively less laccaseinduction. In immobilized mycelia influence of variousparameters on laccase expression was also examined.It is evident from the study that the culture conditionsstudied viz., biomass level, pH, substrate concentration,

Evaluating treatment of Industrial Wastewater by Lab Designedand Fabricated reactor

Biohydrogen Production by Lab Designed and Fabricated Reactor

BIOENGINEERING AND ENVIRONMENTAL CENTREBIOENGINEERING AND ENVIRONMENTAL CENTREBIOENGINEERING AND ENVIRONMENTAL CENTREBIOENGINEERING AND ENVIRONMENTAL CENTREBIOENGINEERING AND ENVIRONMENTAL CENTRE

87

yeast extract concentration, Cu+2 concentration andnature of alcohol showed significant influence on thelaccase yield. Enhanced laccase yield was also evidenceddue to immobilization.

Different Immobilization Matrices for LacticAcid Production

Different polymer matrices were prepared forimmobilization studies for lactic acid production.Evaluation of the matrices was carried out. The matrixshowed higher bacterial cell loading, higher productivityand higher stability under acidic pH conditions.

Bioaugmentation

Bioaugmentation strategy by augmenting immobilizedsulfate reducing bacteria (SRB) in polymer matrix wassuccessfully applied for enhancing anaerobic processefficiency treated sulphate bearing composite chemicalwastewater. Bioaugmentation technique was also usedsuccessfully by inoculating with ETP microflora forenhancing degradation ability of native microflora inbio-slurry phase reactor in the process of treatingpendimethalin contaminated soil.

Laccase Production optimization by Taguchiorthogonal OA approach

The application of a statistical methodology usingdesign of experimental (DOE) approach for theoptimization of culture conditions of laccase productionby SMF. Submerged culture conditions for lacasseproduction by P. ostreatus 1840 was optimized byemploying Taguchi orthogonal array (OA) experimentaldesign (DOE) approach. The obtained optimal culturecondition for the laccase production from the proposedmethodology was validated by performing theexperiments with the obtained conditions. Thisapproach also facilitated the study of interaction of alarge number of variables with a small number ofdesigned experimental region spanned by factors andtheir settings leading to considerable saving in timeand cost for the process optimization. Taguchiexperimental design resulted in evaluating the mainand interaction effects of the selected factorsindividually and in combination in the process of

enzyme synthesis. This methodology also facilitatedanalysis of the resulting experimental data to establishthe optimum conditions for the process, establish thecontribution of individual factors and to establish theresponse under optimal conditions.

APPLIED RESEARCH

Development of Pilot Level Anaerobic Reactor for

Pharmaceutical Waste : The IICT has undertaken this

project under PATSER programme from DSIR for NATCO

Pharma, Hyderabad. Extensive laboratory experiments

were conducted and process variables were optimized

in the laboratory. 2.5m3 pilot scale anaerobic fixed bed

reactor was designed installed and commissioned at

the industry to generate in-situ data for scale up. Pilot

Plant experiments were successfully conducted to

optimize the process variables. Frequent changes in

product profile of modern pharmaceutical industry

usually results in change of waste water characteristics.

Stable reactor performance was achieved by following

specially programmed protocols for maintaining

suitable consortia that can absorb shock loads due to

changing wastewater characteristics. The technology

is proved to be a feasible and attractive option for the

treatment of recalcitrant wastewater by an energy

efficient system.

Treatment of effluents from CETP : An upflow

anaerobic sludge blanket reactor (UASB) was fabricated

in the laboratory. Treatment of composite chemical

wastewater having high sulphate content and low-

Bioengineering and Environmental Centre

1.5 letre Microbial Fermentor (B.Braun)

88

biodegradability was successfully developed and

demonstrated to M/s. Patancheru Efflulent Treatment

Plant in a laboratory studies scaled UASB reactor. Also,

UASB system integrated with ASP and air stripper to

suppress the sulphide inhibition was also

demonstrated at laboratory scale. The integrated

treatment system with pilot scale facility was designed

and submitted.

Enzyme Mediated Degradation : Transformation

of xenobiotic compounds with enzymes as a

pretreatment option to enhance the biodegradability

of wastewater was successfully achieved with free and

immobilized form of enzymes. Lacasse and HRP were

used as oxidative enzymes in the degradation studies.

Degradation of azo dye and anthracene was studied

and very efficient degradation of azo dye and anthrcene

was observed using the enzymes.

Development of High performance Biological

Fluidized Bed Reactor for Antibiotic Production :

Production of antibiotics is one of the important areas

of research in applied microbiology. A high performance

biological fluidized bed reactor was developed for

antibiotic production using immobilized cells of

Streptomyces sp. DST awarded this as a grant-in-aid

project. Continuous fluidized bed reactor was operated

after initial optimization studies involving pH, aeration,

agitation, immobilization matrices, nutrient

requirement etc. for the production of streptomycin

and oxytetracycline. As part of basic research

component several new actinomycete strains also were

also isolated and the compound characterization was

established which resulted in patents and publications.

Periodic Discontinuous Process Development for

theTreatment of Complex Chemical Wastewater :

Periodic discontinuous process was successfully applied

for the complex chemical wastewater treatment. Various

sequencing batch reactor (SBR) configurations

(suspended/biofilm/fixed bed/immobilized bed/GAC

carrier) were studied and optimization along with

varying reactor microenvironmental conditions

(aerobic/anoxic/anaerobic) and phase variations (filling/

reaction/settling/withdrawal). Results showed

enhanced performance of periodic discontinuous

process over the corresponding continuous mode

operating systems. Rapid startup phase, resistance to

shock and transient loads, relatively less HRT, flexibility

of carrying all unit operations in a single reactor,

feasibility to operate at higher organic loading, flexibility

to provide required redox conditions, etc are some of

the major advantages of the periodic discontinuous

operation. Biofilm configured systems showed effective

performance over all other configurations studied.

Aerobic metabolic function provided effective substrate

yield. Inclusion of anoxic phase inbetween aerobic

metabolic function showed to have positive influence

on the performance. One patent was filed on biofilm

configured sequencing batch reactor operated in

periodic discontinuous process.

Decontamination of Soil by Bio-slurry Phase

Reactor : Bio-slurry system operating in periodic

discontinuous operation was developed for the

treatment of contaminated soil. The ability of the

reactor was successfully studied with chlorpyrifos, DEP

and pendimethalin contaminated soil. The slurry phase

system showed enhanced degradation rate over the

corresponding in situ systems. Soil water ratio,

substrate partition, aqueous phase pH, co-substrate

addition, substrate sorption mechanism, metabolic

pathway elucidation was studied.

Contaminated Soil Remediation : Mercury

monitoring in soil matrix and water bodies in and

around a chemical factory was estimated along with its

TCLP characteristics. Remedial measures were

suggested. Mercury analysis was carried out at trace

levels in soil and water matrices.


89

The Engineering Services Division caters to the needs

of all the R&D Divisions and supporting services of the

Institute by ensuring the supply of utilities like power,

steam, water, gas and manages refrigeration services. It

also undertakes fabrication of specially designed

equipment for lab, bench scale studies in R&D divisions

and pilot plant / up-scaling divisions. It also takes charge

of installation and maintenance of utility service lines

in the laboratory and pilot plants. The Engineering

Services Division has participated in the following

activities of the laboratory R&D projects:

Design & development of modern wet

chemical laboratories

Erection & commissioning of 500k VA

transformer, 11 kV VCB panel,

GENERAL ENGINEERING SERVICESGENERAL ENGINEERING SERVICESGENERAL ENGINEERING SERVICESGENERAL ENGINEERING SERVICESGENERAL ENGINEERING SERVICES

Autoclave designed by Nanomaterial group & fabricatedat the workshop

Rice bran stabilisation unit fabricated at the workshop

Development of outdoor 11k V switching yard

Design & Execution of electrical power

Lighting distribution systems for laboratory

R&D projects

Erection and commissioning of Sebacic acid

reactor

Rendering S&T services to BHEL R&D Unit in

Moulali Complex on contractual agreement

Engineering support to Pyrazinamide project

Participated as technical member for

inspection of equipment for degumming and

dewaxing of rice bran oil (RBO) supplied by

Project Engineering Companies to various RBO

Processing Industries across India under TMOP

grant-in-aid assistance project.

90

The Pilot Plant facility is an essential infrastructuralsupport for upscaling of laboratory scale process fortechnology development activity at IICT. The generaland multipurpose pilot plants are basically utilised forupscaling laboratory knowhow prior to transfer toclients. A significant feature of the upscaling activity isthe generation and collection of data for basic anddetailed design engineering. The pilot plant facilityconsists of equipment for a whole spectrum of unitoperations of chemical process industries. The facilityis equipped with all-glass, glass- glass-lined and S.S.reactor systems and all-glass distillation columns withcapacities varying from 20 to 200 litres; rotaryevaporators, dryers, sieve shakers of various capacities,mixing units, spray dryers etc. At times modificationsto existing units are called for to suit certain specialprocess parameters and this is done with in-houseexpertise. Making the pilot plant conducive to theprocess operations is prerequisite for any upscalingstudy. This facility has been extensively used duringthe reporting period for upscaling/optimisingprocesses developed in all applied R&D area of researchat the Institute.

The other component of the upscaling facility at IICTcomprises need based dedicated pilot plants specificallydesigned, fabricated and erected, mostly with inohouseexpertise. Such facilities are developed for processevaluation with respect to its feasibility and commercialplant conditions for the studies. Invariably this isundertaken with sponsorship from industry desirousof commercialising the technology. IICT has set updedicated pilot plants for Mononitrotolunes, TBBA,Benzaldehyde etc.

Disposal of Toxic Gases

IICT has provided technical consultancy services toBharat Electronics Limited., Bangalore for disposing ofchemicals and toxic gases such as Hcl and silane. IICTalso provided training to BEL staff for safety proceduresfor handling gas cylinders. Based on this expertise otherorganisations approached IICT for similar services andnegotiations are in progress.

Cane Bagasse Hydrolysis and AlcoholFermentaion

IICT has provided pilot plant facilities and consultancyservices for M/s Reliance Life Sciences Pvt. Ltd., Mumbaifor conducting trials for producing alcohol usingbagasse hydrolysis. IICT modified the IICT existing pilotplant equipment to suit the process operatingconditions of Reliance for trial runs. IICT scientists alsoparticipated in trial runs and provided consultancyservices for upscaling of the process. M/s Relianceapproached IICT for further utilization of Pilot Plantfacilities for other products based on this experience.IICT also provided pilot plant facilities to outside partieson payment basis. Some of them are:

E&M Chemicals Pvt. Ltd., Hyderabad

AVRA Laboratories Pvt. Ltd., Hyderabad

Saraca Laboratories, Gaddapotharam, Medak Dt.AP

Vishnu Chemicals, Jeedimatla, Hyderabad

Medchal Chemicals & Pharmaceuticals,Hyderabad.

Some of the major sponsored projects utilized pilot plantfacilities are:

Mononitro toluenes

Esfenvalerate

Pheromones

Castor oil based derivatives

Hydroxy ethyl cellulose

Drug intermediates

Speciality chemicals

Degumming of rice bran oil

PILOT PLANT (UPSCALING) FACILITIESPILOT PLANT (UPSCALING) FACILITIESPILOT PLANT (UPSCALING) FACILITIESPILOT PLANT (UPSCALING) FACILITIESPILOT PLANT (UPSCALING) FACILITIES

All glass Pilot Plant unit for process upscaling

91

BUSINESS MANAGEMENTBUSINESS MANAGEMENTBUSINESS MANAGEMENTBUSINESS MANAGEMENTBUSINESS MANAGEMENT

The Business Management Division continued to

function effectively with the following business

development and related activities:

BUSINESS DEVELOPMENT (NATIONAL &OVERSEAS)

Business Development with the arms for

looking after national and overseas business

interests of the organization.

Publicity including Publications, Photography &

industrial campaigns and is responsible for

projecting the image of the Institute outside,

which in turn helps its business interests.

This Division is well equipped with computerized

information, multimedia and documentation facilities.

It is in touch with past and present clients and helps in

providing contract research, consultancy services and

technical services to the clients – both overseas and

national industry.

It is in close touch with the Indian Business Associations

like ICMA, IDMA, BDMA and FICCI. A special brochure

‘Portfolio of IICT Technologies and Services’ is brought

out every year and sent to the parties keeping them

abreast with the latest technologies and services of the

Institute.

For overseas business interests, the Division has

established formal linkages with the overseas

consulting companies looking after its interest in USA

and Europe. Institute also participates in major business

fairs and assemblies to showcase its capabilities in the

field of chemical technology. During 2003-05, IICT has

entered into contract with the following major Indian

and overseas companies:

Overseas

Aisin Cosmos R&D Co. Ltd., Japan

Glaxo Smithkline Beecham, UK

Confluent Surgicals, USA

Givaudan, Switzerland

Dupont, USA

Asian Adhesive Udyog Ltd., Nepal

InnoCentive, USA.

National

Neuland Labouratories Ltd. Hyderabad

Anu’s Labouratories Ltd., Hyderabad

Rajshree Sugars & Chemicals Ltd.,Coimbatore

KCP Biotech Ltd., Hyderabad

DRDL, Hyderabad

Navine Flourine Industries Ltd., Mumbai

Tripura Biotech Ltd., Hyderabad

Central India Ltd., Ghaziabad

Indus Biosciences Pvt. Ltd., Hyderabad

Sai Life Sciences Ltd., Hyderabad

USV Ltd., Mumbai

Max Bond, Bangalore

Balmer & Lawrie Co. Ltd., Chennai

Ashian Herbex Ltd., Chennai

Alchem International Ltd., New Delhi andBangalore

92


Signing of agreement with Inno Centive, USA

Signing of agreement with Asian Adhesive Udyog Ltd., Nepal Signing of agreement with M/S SMS Pharmaceuticales

DST / IICT / Dabur Drug Programme InitiationExchange of agreements with M/S Indo - Swift Ltd.,

93

In addition, the following initiatives were taken forgrowth in contact with outside agencies:

Overseas business delegations were invited tovisit IICT taking in view their strengths andweaknesses in chemical research compared toIICT.

Web based contacts were made with buyersinterests in chemical research.

IICT Website was made more vibrant with theintroduction of Business Management activity asseparate folder.

Distinguished visitors for business are given in theAnnexure :

PUBLICATIONS

Business Management Division played proactive rolein the publications and photography activities. Majorpublications brought out during the reporting periodare given below:

- IICT Bulletin, April 2001 – March 2003

- Diamond Jubilee Book, IICT – 60 Years of Service tothe Nation

- Pouch Folder & Leaflets on IICT Activities

- Brochure: ‘Portfolio of IICT Technologies andServices

Business Management

94

INDUSTRIAL CAMPAIGNS & SEMINARS

Business Management Division actively participated asorganising committee member, in organising the IICTDiamond Jubilee Celebrations which includedimportant seminars, workshops, memorialtournaments & lectures, etc., Details are given in theDiamond Jubilee Chapter separately.

The institute also participated in a number of IndustrialCampaigns to publicise its R&D activities andachievements made. Some of these are:

India Composite Seminar-cum Exhibition (Oct.2003), Hyderabad.

Indian International Trade Fair (Nov 14-29, 2003),New Delhi

Pharma Expo-2003 (Dec 19-21, 2003), Chennai

Save Energy Exhibition (Feb 17-19, 2004),Institution of Engineers, Hyderabad

India Composite Expo-2005 (Feb. 25-26, 2005),Hyderabad

PHOTOGRAPHIC SERVICES

IICT has developed expertise in scientific photographyneeded for R&D projects. Business Management Divisionhas provided photographic inputs to X-ray, biology andtoxicology projects. Photographs given below are takenby digital camera and computer:

(a) Purity of silver in coin (X-Ray), picture takenwithout using photographic camera.

(b) Fungus/bacteria (Biology), picture by digitalcamera highlighting with cross lighting.

(c) Plant eaten by insects/worms (toxicology), pictureby digital camera.

IICT Pavilian in tha Save Energy Exhibition at Hyderabad


95

RESEARCH MANAGEMENTRESEARCH MANAGEMENTRESEARCH MANAGEMENTRESEARCH MANAGEMENTRESEARCH MANAGEMENT

The Research Management Division of IICT plays apivotal role in the management of research projectsand vital activities of the Institute. The projects areplanned, monitored and evaluated by the ResearchPlanning and Budget Committee and the ResearchCouncil of the Institute. The Human ResourceManagement Committee looks after the deploymentof human resources. Various activities and functionalperformance during the period (2003-05) are givenbelow:

PROJECT MANAGEMENT

(a) CSIR Netwoking Projects

IICT has been identified as the nodal laboratory forcoordinating 56 networking programmes / projects forimplementation during the X Five Year Plan period(2005-07) by networking among the CSIR labs. Theselaboratories are: CIMAP, RRL(T), IHBT, RRL(Jorhat), RRL(Jammu), NCL, CFRI, IIP, CECRI, CSMCRI, and RRL (Bhu).The total outlay of these projects is Rs.49.37 crores.Research Management Division is coordinating theseprojects and details are given in CSIR NetworkingProjects chapter of the report.

(b) Major Laboratory Projects

IICT undertook over 150 projects / assignments duringthe period in the area of contract R&D / consultancy /Grants-in-aid projects. Overall ECF received during theseyears and the ECF charts are given in the beginning ofthe report. This division monitors progress of projects,and communicates with clients for receiving payments.This division also arranges for hired manpower i.e.project assistants and research fellows for working inthe projects.

DATA BASE MANAGEMENT: This Division also maintainsmanagement information system for (a) projects (b)

staff (c) awards / honours (d) patents filed / granted, (e)customers’ satisfaction reports, etc. for monitoring theproject and providing details to Director, IICT and toCSIR Hq.

INTELLECTUAL PROPERTY RIGHTS

IICT has recognized the importance of the IPRs by filingpatent applications in India and overseas. This Divisionenthuses scientists working in various divisions of thelaboratory for filing patent applications by renderingassistance in drafting, scrutinizing and sending thepatent applications to IPM Division of CSIR Hq. The listof the patents filed / granted is given in the annexure.

INTERNATIONAL S&T ACTIVITIES (FOREIGNDEPUTATIONS)

IICT scientists are deputed to attend various importantinternational seminars/workshops and also for trainingon sophisticated analytical instruments and to workwith fellow scientists in reputed overseas universities.More than 50 scientists / personnel were deputedabroad during the last 2 years. RM Division coordinateswith CSIR Hq for obtaining necessary approvals andclearances for these deputations.

SEMINARS

RM Division coordinated the activities of DiamondJubilee Celebrations including seminars, curtain raisingevent on August 4,2003 and valedictory function onAugust 4,2004. Every year RM Division organizes,National Science Day, National Technology Day,Founder’s Day, Dr. Sidhu Science Foundation and Dr.P.S.Murti Memorial Lectures. Eminent scientists/industrialists/academicians are invited to deliver keynote address during these days. Details are given inDiamond Jubilee Celebrations chapter.

National Science Day National Technology Day Founder’s Day Lecture

96

The IICT-CCMB Library with its rich reference collectionin the frontier areas of chemical, engineering and lifesciences is consulted not only by the institutional usersbut by researchers in and around Hyderabad.

The print holdings include books, dictionaries, handbooks, encyclopedias, reference book series, etc and theback volumes of journals which are around one lakh innumber. The library subscribes to around 430 Nationaland International journals.

The library is one of the very few libraries in AndhraPradesh which has a complete collection of ChemicalAbstracts from the year of its inception i.e 1907.

The library has taken active steps to computerise itsoperations and acquire digital resources.

DATABASE

This includes Chemical Abstracts on CD , Indian, Britishand ASTM standards on CD, a CD collection ofCompany’s Annual Reports and other CDs receivedthrough subscription of print journals. Database aremade available through the Institute’s intranet to usersat user room facilities recently created.

SCOPUS: It is the largest abstracting and indexingdatabase covering more than14,000 peer reviewedjournals from 4000 international publishers along withcitations search facility.

SciFinder: It is a paid database from American ChemicalSociety for specific search by author, title, structure, etcin Chemical Sciences. Lecture -cum-demo were arrangedfor IICT scientists to use this facility from the Publishers.

Following were the special tasks that have beenachieved during the period:

E-resources: In addition to Science Direct by ElsevierScience Publishers , e-journals from 8 more publishershave been added through CSIR consortium. In all, morethan 3,700 journals can be accessed now at user’s desktops through IICT intranet. Some more e- journals havealso been made available for access by virtue of IICT’sprint subscription .

Training Programme : This was arranged for the Libraryand Information Officers of CSIR Laboratories fromCentral India at the request of NISCAIR of CSIR in usingthe e- journals which include lecture-cum-demo bypublishers and officers from NISCAIR along with handson training.

INFORMATION MANAGEMENTINFORMATION MANAGEMENTINFORMATION MANAGEMENTINFORMATION MANAGEMENTINFORMATION MANAGEMENT

Library Homepage: A homepage of Library viz http://libdoc was designed using Macromedia dream waiverMX2004 and Macromedia fire works MX2004 to bringdigital and e-resources of library on a single platform.Library home page can be accessed via intranet by users.

Through this homepage user can access

- e-journals- both subscribed and free internetjournals,

- Daily new arrivals of journal issues in the library

- List of IICT publications with abstracts

- Internet patent sites

- Free Chemical Information sites on internet

REORGANIZATION AND COMPUTERISATION OFINDIAN PATENTS

As a measure of saving space and also to make theavailable Indian patents retrievable from the year 1943to 1994 (2407patents), loose sheets of Indian patentswere bound into volumes and shelved according totheir patent specification number and computerizedwhich are hitherto irretrievable.

Remote Access Service to ICICI Knowledge Park:Consultancy Project sponsored by ICICI Knowledge Parkhas been completed successfully as per the terms andconditions.

ECF Generation : Through Industrial memberships,consultancy and other services, the division has earnedmore than Rs.40 Lakhs during the period.

Archiving of IICT Publications: Reprints of researchpublications from the staff of IICT were’ collected, indexedand bound into volumes have been displayed in theLibrary for ready reference of the Institute’s researchoutput.

Other Services: Reprographic, Translation, Binding,Document delivery, etc Library services are beingcontinued for the benefit of users.

99

HUMAN RESOURCE DEVELOPMENTHUMAN RESOURCE DEVELOPMENTHUMAN RESOURCE DEVELOPMENTHUMAN RESOURCE DEVELOPMENTHUMAN RESOURCE DEVELOPMENT

TRAINING PROGRAMMES

___________________________________________________________________________________________________Course Date

___________________________________________________________________________________________________

Training Need Analysis, Human Potential Development 28th to 30th Sept. 2004Centre, New Delhi

Insect Pheromones Research & Development Aspects, 16th to 28th Feb. 2004Rajshree Sugars & Chemicals Ltd., Coimbatore

Quality Control of Herbal medicines, Sri J S Ayurvedic 19th to 24th July 2004College, Chennai

One day programme on coal testing and finger printing of coal, 16th July 2004Singareni Colleries, Kothagudam

National Workshop on Modern Chromatographic 29th Dec 2003 to 2nd Jan. 2004Techniques and their Applications in Chemistry, Biochemistryand Pharmacy, Dept. of Chemistry, NIT, Warangal

Training programme for Section Officers on Vigilance 7th to 9th April, 2005 & related issues, Human Resource Development Centre,Ghaziabad

Annual Meet 2004, of Coordinators, PME & 23rd & 24th Jan. 2004Finance Officials, CSIR, New Delhi

Advanced Course in Bioinformatics Two Courses of long duration (about 5 months) conducted

during 2003- 04 and 2004-05

Training Programme for Section Officers Conducted by HRDC,Ghaziabad at IICT

Dr. J.S.Yadav, Director, IICT(Seated third from left) at the NationalWorkshop - Modern Chromatographic Techniques at IICT

100

SYMPOSIA/ SEMINARS/ WORKSHOPSSYMPOSIA/ SEMINARS/ WORKSHOPSSYMPOSIA/ SEMINARS/ WORKSHOPSSYMPOSIA/ SEMINARS/ WORKSHOPSSYMPOSIA/ SEMINARS/ WORKSHOPS

ORGANISED BY IICTORGANISED BY IICTORGANISED BY IICTORGANISED BY IICTORGANISED BY IICT

2003 - 20042003 - 20042003 - 20042003 - 20042003 - 2004

Dr. R. K. Arora, Executive Director, C-DAC visited IICT as a Chief Guest on the inaugural function of “Advanced Coursein Bioinformatics (ACB)” held on 25th June 2003 and Prof. Y. Venkatrami Reddy, Vice Chancellor, JNTU delivered aspecial address.

His excellency Shri Surjit Singh Barnala, the Governor of Andhra Pradesh visited IICT and delivered the 13th Dr. G. S.Sidhu Science Lecture on “Indian Science and its Societal Impact” on 16th July 2003.

Dr. Mrs. Manju Sharma, Secretary, Dept. of Biotechnology, Ministry of Science and Technology, Govt. of India, New Delhivisited IICT and delivered Prof. Y. Nayudamma Memorial Lecture on “Biotechnology Research and DevelopmentTowards Excellence and Self-Reliance for Human Welfare” on 18th July 2003.

Shri Vadde Sobhanadreeswara Rao, Hon’ble Minister of Agriculture, Govt. of Andhra Pradesh visited IICT as a ChiefGuest for the National Seminar held on “Recent R&D Trends in Rice Bran Oil Processing and By-product Utilization”by IICT and Oil Technologists’ Association of India, Southern Zone on 30th August 2003.

Dr. Masami Inada, President M/s Aisin Cosmos, Japan visited IICT as a chief Guest for the Curtain Raiser function “IICTDiamond Jubilee Celebrations (1944-2004)”, held on 5th August 2003.

Prof. Chandrakanth Kokate, Vice Chancellor, Kakatiya University, Warangal visited IICT as a Chief Guest for theInternational Seminar on “Global Scenario of Herbal Medicine” on 19th September 2003.

Dr. R. A. Mashelkar, Director General, CSIR & Secretary, DSIR (GOI) visited IICT and launched the “IICT Diamond JubileeInitiatives” on 21st September 2003. Prof. R. Kumar, Chairman, IICT Research Council presided over the function.

Prof. Y. Venkatrami Reddy, Vice Chancellor, Jawaharlal Nehru Technological University, Hyderabad visited IICT as a ChiefGuest for the CSIR Foundation Day Celebrations held on 26th September 2003.

Dr. B. Chandra Kant Rao, Dental Surgeon, Mahaveer Hospital, Hyderabad visited IICT on 18th November 2003 delivereda lecture on “Health Hazards of Tobacco Smoking” as a part of National Pharmacy Week Celebrations.

Prof. M. S. Ananth, Director, Indian Institute of Technology, Chennai visited IICT to inaugurate the National Seminar on“Fuel to Fuel Cells” from 4th to 5th December 2003.

Shri C. V. Anand, IPS, Vice President, HCA, Hyderabad visited IICT as Chief Guest for the Inaugural function of the“Nayudamma Memorial Cricket Tournament” from 11 – 14 December 2003.

Prof. N. Satyamurthy, Dean, Faculty Affairs, IIT, Kanpur visited IICT to deliver a talk on the IICT Diamond JubileeTeachers Day Celebrations organized jointly by IICT and AP Akademi of Sciences on 5th September 2003. Prof. P. K. SaiPrakash, Hon. Secretary, APAS and Dr. Ratan F. Toorkey, Polymer chemist, EMRC, CIEFL, Hyderabad conducted scientificsessions for the benfit of students.

Prof. Mukul Chand Panday, Member, Hindi Advisor Committee, Home Ministry, Govt. of India and Prof. C. Subba Rao, APState Higher Education Board, Hyderabad visited IICT as the Chief Guests for the Hindi Day Celebrations on 15th

September 2003.

SYMPOSIA/ SEMINARS/ WORKSHOPSSYMPOSIA/ SEMINARS/ WORKSHOPSSYMPOSIA/ SEMINARS/ WORKSHOPSSYMPOSIA/ SEMINARS/ WORKSHOPSSYMPOSIA/ SEMINARS/ WORKSHOPS

101

Dr. P. M. Bhargava, Former Director of CCMB visited IICT as a Chief Guest for launching of K T Achaya Endowment Fundand to deliver the 1st K T Achaya Memorial Lecture on 6th October 2003.

Dr. C. L. Khetrapal, FNA & Distinguished Professor, Centre for Biomedical Magnetic Resonance, Sanjay Gandhi P. G.Institute of Medical Sciences, Lucknow visited IICT to deliver IICT Founder’s Day Lecture on 7th November 2003.

Dr. D. S. Viswanath, Emeritus Professor and Dowell Chair at the University of Missouri, Columbia (USA), visited IICT asChief Guest and delivered 8th P. S. Murti Memorial Lecture on 10th January, 2004.

Dr. R. N. Singh visited IICT as a Chief Guest for the Six Day National Workshop on “Industrial Applications of Chemo-informatics and Computer Aided Drug Design” held on 12 – 17 January 2004. Prof. E. D. Jemmis was the keynotespeaker.

Prof. Klabunde, University Distinguished Professor, Kansas State University, USA visited IICT to deliver a lecture on“Nanoscale Materials” on 23rd January 2004.

2004 - 20052004 - 20052004 - 20052004 - 20052004 - 2005

Dr. (Mrs.) Manju Sharma, Adviser to Minister for Science & Technology, Govt. of India visited IICT to deliver ‘12th S SBhatnagar Memorial Lecture’, on 1st April 2004.

Dr. D. P. Rao, Former Director, NRSA visited IICT as the Chief Guest for the World Earth day at IICT on 22nd April 2004.Dr. S. Jeevananda Reddy, Agricultural Meteorologist delivered a lecture on this occasion.

Dr. A. V. Rama Rao, Former Director and Chairman & Managing Director of M/s AVRA Labs, Hyderabad visited IICT todeliver a lecture on National technology Day at IICT on 11th May 2004.

Dr. R. N. Singh, Ex-Director, NEERI, Nagpur visited IICT as the Chief Guest for the seminar on “Virtual Reality in Pursuitof Excellence” held at IICT on 4th June 2004 as part of the IICT Diamond Jubilee celebrations.

Prof.S.K.Brahmachari, Director, IGIB, New Delhi visited IICT to deliver the 14th Sidhu Science Lecture on “SNPs, Chips,Informatics and Predictive Medicine” on 2nd July, 2004 at NGRI, Hyderabad.

Prof. Abraham Clearfield, Texas A & M University, USA visited IICT to deliver a lecture on “A New Family ofSupermicroporous Oxides” on 21st August 2004.

Inauguration of the Workshop ‘Industrial Applications ofChemoinformatics and Computer aided Drug Design’ at IICT

Symposia / Seminars / Workshops

102

Prof.Nityananda Saha, Vice Chancellor, Kalyani University, West Bengal was the Chief Guest for the CSIR FoundationDay celebrations held on 26th September, 2004.

Prof.Animesh Chakravorthy, IACS, Kolkata visited IICT to deliver Founder’s Day lecture on “A Portrait of Metal Ions”on 9th November, 2004 in memory of Late Dr.S.Husain Zaheer, Ex-Director, IICT and Ex-DG, CSIR.

Prof. Javed Iqbal of Dr.Reddy’s Research Foundation of Hyderabad was the chief guest for the one day nationalseminar on “Industrial Perspective of Bioinformatics” organised on 18th November, 2004 and several eminentspeakers from TCS, IISc, Jubilant Biosys, V-Life Sciences, Schroeindger and Ocimum Biosolutions participated in theseminar.

Prof.Jayant M.Modak, IISc, Bangalore delivered the 9th Dr.P.S.Murti Memorial Lecture on 10th January, 2005 at IICT on“Biotechnology for Refractory Gold Ores”.

Prof.S.Jayarama Reddy, Vice-Chancellor, S.V.University, Tirupati delivered an invited lecture on 27th January, 2005 atIICT on “Electrochemical Techniques: Their Potentialities in Analysis and Synthesis”.

Nobel laureate Prof. Shirakawa delivered lecture on “Synthesis of Polyacetylene” at IICT on 9th February 2005.

Dr.B.M.Choudary, Ex-Deputy Director, IICT delivered a lecture on National Science Day celebrated in collaborationwith APCOST on “Asymmetric synthesis” in commemoration of Einstin’s discovery in 1905 being celebrated withfocus on physics in 2005, held on 28th February 2005.

Dr.S.Siddiqui, University of Illinois , Chicago (USA) delivered a lecture on “TGF-â Signaling in Development andWound healing” on 14th March, 2005.

Prof. Lakshmi Kotra, Director, Molecular Design and Information Technology Centre, University of Toronto, Canadadelivered a lecture on “Structure based Design of Insulin Receptor ligands” on 18th March 2005.

Dr. Patrice Rannous from Synthetic Metals Laboratory, France delivered a lecture on “Ionically Self-Organized andHierarchize Metallic and Thermo stab Poly (aniline) Comb-Shaped Supramolecules: From Basic Science toPlastic Electronic Applications” on 22nd March 2005.

Prof. Pierre H. Dixneuf, University of Rennes, France delivered a lecture On “Ruthenium Catalysts And Fine Chemistry”on 29th March, 2005.

Prof. D.S. Viswanath, Emeritus Professor & Dowell Chair at the University & Missouri,USA (second from left) delivered the 8th P.S. Murti Lecture at IICT (10-01-2004)


103

AWARDEE(S)AWARDEE(S)AWARDEE(S)AWARDEE(S)AWARDEE(S) AWARD/RECOGNITIONAWARD/RECOGNITIONAWARD/RECOGNITIONAWARD/RECOGNITIONAWARD/RECOGNITION

Dr. J.S. YadavDr. J.S. YadavDr. J.S. YadavDr. J.S. YadavDr. J.S. Yadav Goyal Prize (2003) in Chemistry by the KurukshetraUniversity

Vigyan Ratna Award (2002-03) by the Council ofScience & Technology, UP.

Vigyan Gaurav Samman (2004) by the Council ofScience & Technology, UP

Upgradation in the Addl. Secretary’s Grade basedon the recommendations of High PoweredCommittee constituted by the Vice President, CSIR.

Dr. T.K.ChakrabortyDr. T.K.ChakrabortyDr. T.K.ChakrabortyDr. T.K.ChakrabortyDr. T.K.Chakraborty AP Scientist Award – 2005 by the AP Akademi ofSciences

Dr. B.M. ChoudaryDr. B.M. ChoudaryDr. B.M. ChoudaryDr. B.M. ChoudaryDr. B.M. Choudary Fellow, Indian National Science Academy

Andhra Pradesh scientist Award (2004) by the APState Council of Science & Technology

Dr. Prakash V DiwanDr. Prakash V DiwanDr. Prakash V DiwanDr. Prakash V DiwanDr. Prakash V Diwan C K Dandiya Award in Pharmacology (2003)

Prof. B N Ghosh Oration Award from the IndianPharmacological Society, New Delhi

Completed Laboratory Assessor Training Courseorganized by National Accreditation Board forTesting & Calibration Laboratories, New Delhi.

Dr. R.B.N. PrasadDr. R.B.N. PrasadDr. R.B.N. PrasadDr. R.B.N. PrasadDr. R.B.N. Prasad Editor, Journal of Oil Technologists’ Association ofIndia (OTAI)

Dr S Husain Zaheer Award (2002) – OTAI

Dr S D Thirumala Rao Memorial Award (2003) OTAI

FAPCCI Award (2003-04) (Chelikani Atchuta RaoMemorial Cash Award)

Shri K.V.R.S. MurthyShri K.V.R.S. MurthyShri K.V.R.S. MurthyShri K.V.R.S. MurthyShri K.V.R.S. Murthy Chairman, Indian Institution of Plant Engineers-AP chapter and Vice President, Indian Institutionof Plant Engineers- Chennai (Southern Region)

Dr. D. KrishnaDr. D. KrishnaDr. D. KrishnaDr. D. KrishnaDr. D. Krishna Hon. Member, Board of Studies in Statistics underFaculty of science, Osmania University, Hyderabad.

Joint Secretary, Society for the development ofStatistics

HONOURS AND AWARDSHONOURS AND AWARDSHONOURS AND AWARDSHONOURS AND AWARDSHONOURS AND AWARDS

104

Dr. U.S.N. MurthyDr. U.S.N. MurthyDr. U.S.N. MurthyDr. U.S.N. MurthyDr. U.S.N. Murthy Member, Governing Council & Research Council,

AP State Sericulture Development Institute

Dr. S.ChandrasekharDr. S.ChandrasekharDr. S.ChandrasekharDr. S.ChandrasekharDr. S.Chandrasekhar AVRA Young Scientist Award – 2004

Dr. J.V. RaoDr. J.V. RaoDr. J.V. RaoDr. J.V. RaoDr. J.V. Rao Member, Board of Studies, Biotechnology,Osmania University, Hyderabad

Dr. (Mrs) P.Usha RaniDr. (Mrs) P.Usha RaniDr. (Mrs) P.Usha RaniDr. (Mrs) P.Usha RaniDr. (Mrs) P.Usha Rani Dr. (Mrs) Jagdishwari Rao Award – 2004 by theApplied Zoologists Research Association (AZRA)

Dr. V.J. RaoDr. V.J. RaoDr. V.J. RaoDr. V.J. RaoDr. V.J. Rao Chemical Research Society of India, Bronze Medal-2004

Dr. R. Nageswara RaoDr. R. Nageswara RaoDr. R. Nageswara RaoDr. R. Nageswara RaoDr. R. Nageswara Rao Outstanding Pharmaceutical Analyst Award (2004)by the Indian Drug Manufacturers’ Association(IDMA)

Dr. Ch. VenkateswarluDr. Ch. VenkateswarluDr. Ch. VenkateswarluDr. Ch. VenkateswarluDr. Ch. Venkateswarlu Associates Fellow, AP Akademi of Sciences

Dr. K.V.S.N. Raju &Dr. K.V.S.N. Raju &Dr. K.V.S.N. Raju &Dr. K.V.S.N. Raju &Dr. K.V.S.N. Raju & Indian Paint Association (IPA) Award-2004

Shri D.K. ChatopadhyayShri D.K. ChatopadhyayShri D.K. ChatopadhyayShri D.K. ChatopadhyayShri D.K. Chatopadhyay

Dr. Paramjit GroverDr. Paramjit GroverDr. Paramjit GroverDr. Paramjit GroverDr. Paramjit Grover Fellow, Academy of Sciences for Animal Welfare

Dr. U.C. KulshresthaDr. U.C. KulshresthaDr. U.C. KulshresthaDr. U.C. KulshresthaDr. U.C. Kulshrestha CSIR Young Scientist Award (2004) in Earth,Atmosphere, Ocean & Planetary Sciences

M S Krishnan Gold Medal (2004) instituted by theIndian Geophysical Union

Dr. M.S.L. KarunaDr. M.S.L. KarunaDr. M.S.L. KarunaDr. M.S.L. KarunaDr. M.S.L. Karuna O P Narula Young Scientist Award (2003)– OTAI

Dr. P.P. ChakrabartiDr. P.P. ChakrabartiDr. P.P. ChakrabartiDr. P.P. ChakrabartiDr. P.P. Chakrabarti Jt. Editor, Journal of Oil Technologists’ Associationof India (OTAI)

Shri S. SridharShri S. SridharShri S. SridharShri S. SridharShri S. Sridhar Amar Dye-Chem Award of IIChE (2003)

National Award for Excellance in R & D for ChemicalEngineering by IIChE in 2003

Dr. Sanjit KanjilalDr. Sanjit KanjilalDr. Sanjit KanjilalDr. Sanjit KanjilalDr. Sanjit Kanjilal O P Narula Young Scientist Award (2002)-OTAI

Shri K.V.S. RanganathShri K.V.S. RanganathShri K.V.S. RanganathShri K.V.S. RanganathShri K.V.S. Ranganath Dr K V Rao Scientific Society Award

Shri A. PrabhakarShri A. PrabhakarShri A. PrabhakarShri A. PrabhakarShri A. Prabhakar Dr.K.V.Rao Scientific Society Award

Miss B. SmithaMiss B. SmithaMiss B. SmithaMiss B. SmithaMiss B. Smitha Late Laxmi Nandkumar Award for bestPresentation at CHEMCON-2004


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DIRECTORDR. J.S. YADAV

SCIENTIST-GDR. A. C. KUNWARDR. M. VAIRAMANI

SCIENTIST-FDR. G.S. SALVAPATISRI. VEDANTA CHARYDR. K.B.S. PRASADDR. K. BABU RAODR. C.V.S. MURTYDR. B. VISHWANADHAMDR. P.S. SAI PRASADSRI. K.B.S. SAIBABUDR. P. NAGESHWARA SHARMASRI. PRADEEP KUMARDR. Y. BHASKAR RAOSRI. G. SAMPATH KUMARSRI. AHMED KHANSRI. S. NARAYAN REDDYSRI. VIJAY KALESRI. B. SANKARIAHSRI. K. VENKATESHWARLUDR. N.KISHAN REDDYSRI. K. PREM KUMARSRI. S. VENKATESWARA RAODR. MOHD. KIFAYATULLAHDR. B.B. GAWALISRI. A. KRISHNA REDDYSRI. K. RAJESWARA RAOSRI. B. BAL REDDYSRI. M.R.K. MURTHYSRI. K.V.R.S. MURTHYDR. R.B.N. PRASADDR. M. RAMAKRISHNASRI. C.V. SUBBA RAODR. D.H.L. PRASADSRI. K.V. RAMANAYYADR. V.V. NARAYANA REDDYDR. AHMED KAMALDR. D. KRISHNADR. B. NARSAIAHDR. B. VITTAL RAODR. PRAKASH V. DIWANDR. K. RAMA RAODR. R. ADAPA SRINIVASDR. U.S.N. MURTHYDR. M. LAKSHMI KANTAM

SRI S.J.D. VARAPRASADDR. M. SUBRAHMANYAMDR. T.K. CHAKRABORTYDR. M. HARI BABUDR. J. MADHUSUDANA RAODR. I. SURYANARAYANADR. B. RAMACHANDRA REDDYSRI. G.A. REDDY

SCIENTIST-EIIDR. S. CHANDRASEKHARDR. G.V. MADHAVA SHARMADR. T.N. SRINIVASANSRI. K.S. RAGHUNANDANSRI. K.V.S.A. RAODR. MS. P. SITADEVIMS. KRUPADEVI OMPRAKASHSRI. S.V.S. RAJUSRI. T.E. VITTAL PRASADSRI. R.K. VENKATA RAMANASRI. T. RAJAIAHSRI. G. RAVINDRANATHSRI. T. SURYANARAYANASRI. K.V.L.N. PRAKASHSRI. V. RAJAGOPALDR. CH. VENKATESWARLUDR. A.S.R. KRISHNA MURTHYSRI. P.S. BHASKARDR. B.S. SITARAMAMSRI. M.G.V. CHALAPATHI RAODR. M. MARTHANDA MURTHYDR. MS. B. KRISHNAKUMARISRI. G. NARSIMHA REDDYDR. Y.V.D. NAGESWARDR. V. VENKAT RAOMS. SAKTIMAYEE MITRA ROYSRI. I. BALAKISHAN RAODR. V. VIJAY KUMARSRI. K. RADHAKRISHNANDR. MS. ANNAPURNA JETTYSRI. B. BHOOLOKA RAOSRI. C.P. RAMULUDR. MS. C. SNEHALATHA NAIRDR. P. VIJAYALAKSHMISRI. SHARAD SHIRADKARSRI. J.V. PRASADMS. USHA VIRENDRA REDDYSRI. D.M. AKKEWARSRI. B. MADHUSUDHAN

DR. A. SESHU KUMARDR. K. ISHRATULLADR. M.S.R. MURTHYDR. L.V. SIVAJIDR. MS. V. DURGA KUMARISRI. P. RAVI PRASADSRI. K.H.V. PRASADSRI. T. KRISHNUDUSRI. D.V. MOHAN RAODR. A. BHASKAR RAOSRI. K. RAVINDRANATHDR. K. JEEVA RATNAMDR. P. SHANTHAN RAODR. MS. P. USHA RANIDR. R. NAGESWAR RAODR. A.R. PRASADDR. Y. RAM BABUDR. B. MAHIPAL REDDYDR. R. SRINIVASDR. MS. S.S. MADHAVENDRADR. B. JAGANNADHDR. R. NARENDERDR. IMTIAZ AHMED ANSARIDR. H.M. MESHRAMDR. M. RADHAKRISHNADR. Y. VENKATESWARULUSRI. N.W. FADNAVISDR. J. VENKATESWARA RAODR. V. VISWANATHANDR. S.J. KULKARNIDR. V. JAYATHIRTHA RAODR. K. RAVI KUMARDR. B.S. RAODR. BISWANATH DASDR. K. BHANU PRAKASHDR. PARICHAY KUMAR DASDR. B. VENKATESWARA RAODR. K.V.R. CHARYDR. ARABINDA CHAUDHURIMS. C.B. LAKSHMIDR. K. CHANDRA SEKHAR

SCIENTIST-EIDR. K.V.S.N.RAJUSRI. C.L.N. MURTHYDR. K.S. RAMA RAODR. MS. PARAMJIT GROVERDR. B. RAMA RAODR. K. SIVAJI

STAFF AS ON 01/04/2005STAFF AS ON 01/04/2005STAFF AS ON 01/04/2005STAFF AS ON 01/04/2005STAFF AS ON 01/04/2005

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DR. R. SEKHARDR. A. KRISHNAIAHSRI. HARISIMHADR. U. ASHUTOSHDR. MS. K. YAMUNARANIDR. D. VIJAYAKUMARDR. P. RADHAKRISHNASRI. D.V.R. MURTHYDR. K. NAGAIAHMS. D. SHAILAJADR. D. SUBHAS BOSEDR. MS. LALITHA KUMARIDR. MS. G. SABITHASRI. K. SATYANARAYANADR. R.S. PRAKASAMSRI. M.H. UPADHYAYASRI. G.A. RAJUDR. G. KUMARASWAMYSRI T. SHEKHARAMDR. S. RAGHAVANDR. S. PALANIAPPANDR. B. JAGADEESHDR. A.K. TIWARISRI. JOHNY JOSEPHDR. MRS. K.N. JYOTHIDR. MRS. A.L. PRASUNADR. G. NARAHARI SASTRYDR. MS. S.V. MANORAMADR. B. SREEDHARMR. A. GANGAGNI RAO

SCIENTIST-CDR. TAIMUR ATHERSRI. PRAVIN RABAJI LIKHARSRI. M. RAMULUSRI. P. SAMMAIAHSRI. T. PRATAP KUMARDR. B. DAVID RAJUDR. K.SRINIVASSRI. B.V.SATYA RAMESHDR. K.I. SURESHMS. S.INDU KUMARIDR. B.L.A. PRABHAVATHI DEVIDR. S. RAMA MOHANDR. MS. B. SATYAVATHISRI. S. ANAND KUMARSRI. S. SRIDHARDR. M. SRIDHARDR. N. LINGAIAH

DR.PRADOSH P. CHAKRABARTIMS. A. MANJULASRI. S. PRABHAKARDR. U.C. KULSHRESTHADR. MS. GHOUSIA BEGUMMS. K.N. PRASANNA RANIDR. MS. G. SARALA DEVIDR. M. MOHAN RAODR. S. RAMAKRISHNASRI. M. CHANDRASEKHARAMSRI. T.V.S.N. MURALI KRISHNASRI. M. PRADEEP KUMARDR. RAJIV TRIVEDIDR.(MRS) MONIKA J. KULSHRESTHADR. RAJKUMAR BANERJEEDR. A.V. SUBRAHMANYA SARMADR. ROHIT KUMAR RANA

SCIENTIST-BDR. P. ARUNADR. B. SRIDHARDR.(Mrs) SOUJANYA YARASIDR. B. CHINNA RAJUMS. M. SRI LAKSHMI KARUNAMS. SUTAPA GHOSHSRI. SAMUEL L. RALTEDR. N. NARENDERDR. H. MAHESWARANDR. A. VENUGOPALDR. K. RAJENDER REDDYSRI G. UMA SANKARDR. N. LINGAIAHSRI. U.V.R. VIJAYA SARATHISRI. R. SRINIVASANMRS. C. SUMANADR. S. VENKATA MOHANSRI. P.V. SRINIVAS

TECHNICAL OFFICER EIISRI. K.V. AVADHANULUSRI. B. PRAKASH RAOSRI. UDAY RANGREZDR. MS. BHARATHI DEVKUMAR

TECHNICAL OFFICER EISRI. K. BHUPAL REDDYSRI. C.R.C. RAJUDR. A.R.K. SASTRYSRI. P. DATTATREYA SARMASRI. K. RAMACHANDRA RAO

SRI. AHMED HUSSAINSRI. M. RAGHUVIRSRI. B. VASUDEVAMS. T.S. CHANDRA KALASRI. J. NARASIMHA CHARYSRI. D. RAMAKRISHNASRI. C. LAKSHMI KANT RAOSRI. P. YOGENDRANATHSRI. G. RAJESHWAR RAOSRI. P. RAMA RAOSRI. ARIVENI SATYANARAYANASRI. K.V. RAMANAMURTHYSRI. S. TAJUDDINSRI. R. NARSIMHASRI. N.S. SWAMYDR. V.S. KISHAN PRASADSRI. ARUN KANTI DASDR. M. VENKATESWARA RAOSRI. A. KUMARSRI. K. NARSIMAIAHSRI. A.P. RUDRA DASSSRI. S.K. ROYDR. MS. K. PARVATISRI. HARSHA VARDHANSRI. B. KRISHNAMACHARYULUDR. N. PRASADA RAJUSRI. P.V.K. RAJUSRI. E.V.R. HANUMANTH RAODR. K. KOTESWARA RAOSRI. C. EFREMSRI. K. SITARAMA RAODR. K. RAMAKRISHNAM RAJUSRI. P. NAGESWAR RAO

TECHNICAL OFFICER-CSRI. MOHD. RIAZUDDINSRI. B.R. VENKATESHAMSRI. ARADADA SATYANARAYANASRI. C. RAMACHANDRANSRI. N. PREM KUMARSRI. V.G. JACOBSRI. S. CHANDRA REDDYSRI. M. SOMESWAR REDDYDR. B.V.S.K. RAOSRI. A. RAMACHANDRA RAOSRI. M. SUBRAMANYAMDR. MS. I. MARGARETSRI. K.V. VENKATESWAR RAOSRI. K. GOPI KRISHNA

107

SRI. A. VISHWANATHSRI. G. RANGA RAOSRI. G. VIJAYA MURTHYSRI. CH. BABU RAOSRI. P. KRISHNA MURTHYSRI. N. NALINI SEKHARSRI. ATUL NANDEDKARSRI. K. SHANMUGAMMS.SHOBHA RAJENDRAPATHAKSRI. A. MADHAVA RAODR. MOHD. MAHBOOBSRI. A. NARASIMHA RAOSRI. Y.V.L. RAVI KUMARSRI. A.S.P. RANGA PRASADDR. D. RAJA GOPALDR. G.Y.S. KUMARA SWAMYSRI. A. RADHAKRISHNASRI. P. SIVAJEESRI. C. SUDHAKARDR. RAJEEV ARABSRI. P. RAMAKRISHNA RAOSRI. G. VASUDEVA RAODR. MOHD. FAZLUR RAHMAN

TECHNICAL OFFICER-BSRI. Y. CHANDRASEKHARSRI. K.V. SATYANARAYANA MURTHYSRI. D. KRISHNASRI. A. SUDHAKAR REDDYSRI. P. BICHAPPASRI. V. SIVARAMA SASTRYMS. D. GAYATRISRI. G. NAGI REDDYSRI. S. HEMANT KUMARMS. K.B. AMITADR. MS. M. SATYAKALASRI. T. PRABHAKAR RAOSRI. T. VENUGOPAL RAJUSRI. K. SRIRAMSRI. DAMODAR JOSHIDR. HAFEEZ - UR - REHMANSRI. T. NAGESHWAR RAOMS. SARA KHALIDMS. K. BHUVANESHWARIMRS. G. SHEELUSRI. S. SRIKAMALDR. G. BASKAR RAJAN

TECHNICAL OFFICER-ASRI. Y. SRI RAMA MURTHYSRI. RAVILUKE BABUSRI. T. MAHESH BABUSRI. K.S.A. VISHNUVARDHANSRI. P. RAVINDER GOUDDR. MS. M. SHYAMALADR. S. RAJARAMSRI. B.S. SASTRYSRI. U. SAMPATH KUMARDR. K. VENKATRAM REDDYSRI. B. ASHOK KUMARSRI. CH. RAMESHSRI. M. SRIDHAR KUMARSRI. K. SHIVA KUMARSRI. L. SATYANARAYANASRI. J. LAXMI KANTH RAOSRI. A. RAMA KRISHNA REDDYSRI. K. SUGNANA SUNDERSRI. A. VENKATA NARSAIAHSRI. B. RAJA SHAKERMS. B. RENUKASRI. K. SARAVANANSRI. SUNIL KUMARSRI. B.V. DEVENDRA RAO

EXECUTIVE ENGINEERSRI. P. NARAYANA RAO

ASSISTANT ENGINEERSRI. CH. SRINIVAS

MEDICAL OFFICERDR. MS. V. VARSHA GAYDHANKAR

SR.TECHNICAL ASSISTANT(GR.III)SRI. K. KIRANSRI. R.BOOPATHYSRI. G. RADHA KRISHNA MURTHY

TECHNICAL ASSISTANT (GR.VIII)(GR.III)MRS. BHAGYA LAKSHMI M.G. SRI. KIRAN KUMAR A. SRI. MADHU SUDHANA K. SRI. MURTY MRVS. SRI. NARSINGH K. SRI. NIRANJAN A. SRI. RAVI KIRAN I.

SRI. RAVINDER T. MS. ROHITHA C.N. SRI. SATISH KUMAR D. SRI. SATYA RAO D. SRI. P. SIVA NARAYANAN SRI. SRINIVAS PVSS

TECHNICAL OFFICER A(GR.II)SRI. S. JANAKIRAMANSRI. V. KRISHNAMA CHARYSRI. MOHD. ISHAQ ALISRI. SYED KURSHEED AHMEDSRI. S. NARSING RAOSRI. D.PENTAIAH / NARASIMHASRI. MOHD. IQBALUDDINSRI. P. YADAGIRI / DURGAIAHSRI. P. RANGAIAH / KISTAIAHSRI. M. SANJEEVA RAOSRI. SALAHUDDINSRI. SALLAHUDDIN AHMEDSRI. P. VEERABHADRA RAOSRI. K. YADGIRI / MALLIAHSRI. R.RAMULU / MUTHAIAHSRI. G. CHANDRAIAHSRI. B. VENKATESHAM /NARASIMHASRI. K. MALLA REDDYMS. FATIMA ALI KHANSRI. P. NIRANJAN RAOSRI. SYED KAREEMUDDINSRI. P. SATHYA PRASADSRI. P. C. LOHARSRI. J. ASHAIAHSRI. RAJ BHOOMAIAHSRI. M.C. THOMAS

SR. TECHNICAL ASSISTANT(GR.II)SRI. ABBAS ALI/LIAQAT ALISRI. ABDUL AZEEM/RAOFF SRI. ABDUL REHMAN SRI. ADISHESHU Y. SRI. AMARENDRA KUMAR P. SRI. ATHER MEHDI S. SRI. BABU SRI. BALARAJ E. SRI. MD. BHAVALISHA SRI. BHIKSHAPATHI K.

Staff As on 01/04/2005

108


SRI. BIKSHAPATHI D. SRI. CHANDRAPAL M.R. SRI. CHARAVANDA REDDY E. SRI. DANAIAH K. SRI. EASHWARAIAH K. SRI. EASHWARJI N. SRI. GOVERDHAN R. SRI. KAMALAIAH C/RAMASWAMY SRI. KAMESHWAR RAO K. SRI. LACHAIAH SRI. LINGAM D. SRI. J.V. S.N. MURTHYSRI. MAHBOOB SHAREEF SRI. MALLESHAM K. SRI. MOHAN RAO R. SRI. MOHD. GHOUSUDDIN SRI. MOHD. IQBALUDDINSRI. T. SRINIVASAN SRI. MOHD. ISHAQ ALI SRI. MOHD. SARDARUDDIN SRI. MOHD. TAJUDDIN SRI. MOHD.HAYAT/OSMAN SRI. MURARILAL N. SRI. NAGESHWAR RAO V. SRI. NANDA GOPALAM G. SRI. NARASIMHA D/RAMULU SRI. D. SHANKARIAH / MYSAIAHSRI. BALAIAH / POCHAIAHSRI. MOHD. WAHIUDDINSRI. P.V. SAIBABUSRI. M. KHADEER KHANSRI. NARASIMHA REDDY E. SRI. NARASIMHA/MAISHAIAH B. SRI. NASEERUDDIN ALVI DR. S. SRI. OOSHAIAH/THRUPATAIAH S. SRI. PRASADA RAO D. SRI. QAISER ALI SRI. RAJA RATHNA N. SRI. RAM MOHAN RAO P. SRI. RAMACHANDRAIAH B. SRI. RAMESH P. SRI. RAMULU M/RAJAIAH SRI. RAMULU R/MUTHAIAH SRI. RAVI P.V. SRI. RAVINDER A. DR. K.V. RAMPRASADSRI. M. SYAM SUNDERSRI. SANJAY B.D.

SRI. SAYED AZIZ MS. SHASHIREKHA V. SRI. SHIVAJI G.R. SRI. SIDDIRAMULU M. SRI. SRIDHAR B. SRI. SUGREEVA REDDY N. SRI. SWAMY J. SRI. SWAMY/SOMAIAH N. MRS. SYEDA BEGUMSRI. SYED KURSHEED AHMED SRI. SYED MASID MIAN SRI. SYED ZAFAR ALI SRI. UTTAM KUMAR M. SRI. VARDHARAJAN S. SRI. VEERAIAH/ELLAIAH SRI. VENKATESHWARA RAO M. SRI. VIJAY KUMAR B. SRI. VIJAYA KUMAR CH. SRI. VIJAYAN K.V.SRI. VIVEKANANDA T.G. SRI. YADAGIRI G/MANKAIAH SRI. YADAGIRI P/DURGAIAH SRI. YOUSUF ALI SRI. ABDUL MANNANSRI. AHMED BIN ABUBAKERSRI. JAI PRAKASH MS. SUMATHI REDDY S. MS. SURYA KUMARI K.SRI. SYED BABU SRI. UMA MAHESWARA SARMA V. MS. URMILLA REDDYSRI. K.V.N. SATYA SRINIVASSRI. J. SRI RAM MURTHYSRI. T. RAMESH BABUSRI. G. VEERAIAHSRI. B. CHANDRASEKHARSRI. LAKSHMI PATHI RAJU V.

TECHNICAL ASST. GR.VII (GR.II)SRI. ACHAL SINGH SRI. ANJAIAH N. SRI. FARHATH HUSSAIN SRI. KALIDAS S. S/O YADAGIRI SRI. MADAN KUMAR S/O SAMBIAH SRI. MADHUSUDAN RAO K. MS. MERCY JOSEPH SRI. P.B. GAWALISRI. R. MAHESHWAR RAO

SRI. K. VENKATA NARAYANAMRS. CH. JAGADESWARISRI. T. KRISHNA REDDYSRI. MOHD. WAHIUDDIN SRI. MOHD. AKBARSRI. NAQVI S.B.A. MS. NILOFER RAHMAN MS. PARVATHI D.SRI. PAVANRAJ B. SRI. PRASAD K.S.S.CH. SRI. PULYA NAIK M. SRI. RAJENDAR S. SRI. RAMA KRISHNA K.V.S. SRI. RAMA KRISHNA M. SRI. RAMESH N. SRI. RAMULU P. SRI. RAMULU K.SRI. ROHINI KUMAR D.B. SRI. SATYADEV G. MS. SHAILAJA S. SRI. SRINIVAS B. MRS. SWAPNA V. MS. SWARAJYA LAKSHMI V.V. MS. SWARNA LATHA CH. MS. SWARNALATHA Y. MS. VIJAY MARY A. SRI. VIJAYAKUMAR K. MS. ZEHRA ALI MS. MS. A.V.L. SUBHADRA

TECHNICIAN ASST. GR.VII (GR.I)SRI. BALAIAH K. / ELLAIAHSRI. ACHAIAH/PENTAIAHSRI. ASHOK G/MANKAIAH SRI. BABU RAO P/ ACHIAH SRI. BADIUDDIN SRI. BALAIAH G/JANGAIAH SRI. BALRAJ B/POCHAIAH SRI. BIKSHAPATHI G/BALAIAH SRI. BIKSHAPATHI/NARASIMHA SRI. CHENNAYYA B. SRI. DARSHAN B/AGAIAH SRI. DASARATH J. SRI. M. SHABBIR ALISRI. M.A. RASHEEDSRI. DASHRATH D. SRI. DEVASHAYYAM SRI. EASHWAR/ELLAIAH N.

109

MS. G. YENKAMMA / MOGLIAHMS. GANGAMMA R. SRI. GEORGE ANTHONY DAS MS. GHOUSIA BEE/BASHEERU SRI. GHOUSUDDIN JAFFAR SRI. HUSSAIN S.K./AFZAL S.K. SRI. ISMAIL KHAN/KAREEM SRI. JAHANGIR S/SD. AHMED SRI. JANGAIAH M/BABAIAH MS. KAREEMUNISA BEGUM SRI. KRISHNA B/MAISHIAH SRI. KRISHNA B/SATHAIAH B. MS. LAKSHMI P/NARASIMHA SRI. MAISAIAH B/LAKSHMAIAH SRI. MAISIAH K/ACHAIAH SRI. MALLAIAH B/CHENNAIAH SRI. MALLESH A/BALAIAH SRI. MALLESH B/GANDAIAH SRI. MALLESH S/RAMAIAH MS. MANIKYAMMA N. SRI. MIRZA MD. BAIG/MORAD SRI. MOHAN RAO P/SWAMY SRI. MOHD. GHOUSE/SHARFUDDIN SRI. MOHD. HUSSAIN SRI. MOHD. IQBAL /MD. YAKOOBSRI. YADAGIRI / BABAIAHSRI. N. YADAGIRI / RAJAIAHSRI. MOHD. JAFFAR SRI. MOHD. KHAN /ISMAIL KHAN SRI. MOHD. MAQBOOL SRI. MOHD. NASIRUDDIN SRI. MOHD. YOUSUF/GALIB MOHD. SRI. MOHD. YOUSUF/ISMAIL MOHD. SRI. MUMILL M.A/M.A.HAI SRI. MUMTAZ AHMED SRI. NAGAIAH/KISHTAIAH K. SRI. NARASIMHA CHARI G. SRI. NARASIMHA K/BALAIAH K. SRI. NARSING RAO K. SRI. NARSING RAO T/KUMARAIAH SRI. NISAR HUSSAIN/ABIDI SRI. PANDU M/MYSAIAH SRI. POCHAIAH B/ACHAIAH SRI. N. YADAGIRI / ELLAIAHSRI. A. YADAGIRI / KODAIAHSRI. T.H. NARASIMHASRI. N. YADAGIRI / THIRUPAIAHSRI. S. SHARFUDDIN

SRI. PARVATHULU / NARASIMHASRI. PRABHAKAR K. SRI. RAJVEERAIAH A/ISTARI SRI. RAMSINGH/KISHAN SINGH SRI. RAMULU E/POCHAIAH SRI. RAMULU G/NARASAIAH SRI. RAMULU M/CHANDRAIH M. SRI. RAMULU K / MANKAIAHSRI. RAMULU S/DURGAIAH SRI. RASHEED M.A./S.K.KHAN MS. RATNAMMA MS. D/KRISHNA SRI. RAVINDER C/RAMASWAMY SRI. SHAIK MUNEER / MAQDOOMSRI. SAMSON B/ISMAIL B. SRI. SANDAIAH G/PAPAIAH SRI. SATHYANARAYANA G/RAJU SRI. SATHYANARAYANA K. SRI. SATHYANARAYANA REDDY G. MS. CH. VENKATARATNAMSRI. G. VENKATESH / G. SWAMY

TECHNICIAN GR. II(GR.I)SRI. AZIZ PASHA SRI. BHUPAL S. MS. JAGADESWARI CH. SRI. MAHESHWAR RAO R. SRI. MEHARBAN SINGH S. SRI. NARSING RAO N. SRI. POCHAIAH B. SRI. PRASAD P. L. SRI. SATYANARAYANA SRI. VENKATESHWARLU P. SRI. ABDUL HAFEEZ SRI. ALIMULLAH KHAN MS. ANASUYA V. SRI. ANTHAIAH D/MAISAIAH SRI. BABUL A. SRI. BALAIAH A/RAMASWAMY SRI. BHIMLA/LINGAIAH MS. CHANDRAMMA S/MALLAIAH SRI. DAMODAR G. SRI. ELLAIAH R./RAMAIAH SRI. FAREED AHMED S. SRI. GAJULA SAI GANESH SRI. GANESHWAR C. SRI. GOPALAKRISHNA D. SRI. HARISH CHANDER/SOMULA

MS. M. SHUKLAMMASRI. H.K. HUSSAIN / AFZALMS. D. SHIVA PARVATHISRI. JAIKISHAN D/NAGAIAH SRI. KRISHNA SRI. LAKSHMAN RAO M. SRI. MADHUSUDAN RAO V. SRI. MALLESH T/RAJAIAH MS. MANIAMMA MS. K. MS. MEERABAI SRI. MIRZA MOHD HABEEB SRI. MOHD. AHEMED/AKBAR SRI. MOHD. AKBAR/A.SUKOOR SRI. MOHD. MOINUDDIN/MD.JAFFAR SRI. MOHD. ODUD/MD.YOUNUS MS. NARSAMMA D/RAJAIAH SRI. NARSING RAO N/RAMULU MS. NIRMALA MS. M. SRI. OMPRAKASH K. SRI. PANDU E/RAMAIAH SRI. PEDDULU B. SRI. RAMAMURTY G. SRI. G. SRIRAMULU / RAGAIAHSRI. RAMJEE/PARTHAIAH SRI. SAIANNA G. SRI. SD. MOINUDDIN/SDASADULLASRI SHAIK DAWOODSRI. SUDERSHAN L/BAGAYYA MS. SUJATHA R. SRI. SYED SHARIEFSRI. SYED ABDUL KHADEERSRI. SHAIK AHMED / MAHBOOBSRI. SURENDER G. SRI. SYED ALI RAZA SRI. THREEMURTHULU S. SRI. VENKATESHAM P SRI. YADAGIRI T / BALAIAHSRI. YADAGIRI A /RAMULU SRI. YADAGIRI A /VENKAIAH SRI. M. YADAIAH / POCHAIAHSRI. YADAIAH D/ RAJALINGAIAH MS. YADAMMA M/PENTAIAH SRI. YELLAIAH S./BAGAIAH SRI. ZAHEED HUSSAIN M SRI. ABDUL HAFEEZSRI. SHAIK YOUSUFSRI. R. ELLAIAH / RAMAIAH

Staff as on 01/04/2005

110


HELPER-BSRI. MAHBOOB ALISRI. K.M. EASHWAR RAOSRI. SALIM BIN MAHBOOBSRI. D.ANTHAIAH / MAISAIAHSRI. BHIMLA / LINGAIAHSRI. KHAJA MOINUDDINSRI. ASADULLAHSRI. T.MALLESH / RAJAIAHSRI. V.P.SRINIVASA RAOMS. M. ANASUYA /KRISHNAMS. K. YELLAMMAMS. K. GOKARAMMA

HELPER-ASRI. J. VENKATESHSRI. BHIKSHAPATHI T. SRI. MUSHTAQ AHMED SRI. RAMULU P. SRI. RAMULU P. SRI. SATYANARAYANA RAJU R

ADMINISTRATIONCONTROLLER OF ADMINISTRATIONSRI. RAKESH K. SHARMA

ADMINISTRATIVE OFFICERSRI. N. PRAKASHAM

STORES & PURCHASE OFFICERSRI. S. GNANAPRAKASAMMS. B. SANDHYA RANI

FINANCE & ACCOUNTS OFFICERSRI. M.R.K SASTRYSRI. K.CHANDRASHEKAR

SECTION OFFICERS (G,F&A,S & P)SRI. BINOD DUBEY SRI. JAGANNADHA RAO R.L.V. MS. JYOTHI RANI K SRI. MURTHY DS MS. SUDHA RANI P. SRI. SUNIL KUMAR SRI. V.VIDYA BHASKARSRI. M. ANANDA KUMARMRS. M.P. GEETHAMRS. P.RAJYALAKSHMISRI. Y. SANYASI RAOMS. T. MANOJA PRASAD

SRI. R. DEVARAJULU CHETTYSRI. B. SRINIVASSRI. MAHIPAL SINGH

SR. HINDI OFFICERMRS. V. SAILAJA GIRI RAO

HINDI OFFICERDR. (MS) S. NASEEMA

SECURITY OFFICERSRI. P.R. CHITNAVIS

PRIVATE SECRETARYSRI. V.S.N. MURTHYSRI. G. NARSING RAOSRI. P.G.K. MURTHYSRI. M. MALLIKARJUNA RAOSRI. A. RAGHURAMANMRS. V.V. SUBBALAKSHMIMRS. B. MALLIKAMBA

ASSISTANT GR I(GEN. / F&A/S&P)SRI. GULAM MURTUZASRI. K.SEETHARAMAIAHSRI. V.MUTHENDERMRS. A. SITAMAHALAKSHMI DEVISRI. K.V.S.PRABHAKARSRI. P.VISHVESHWARA RAOMRS. L.RATNA MANIKYAMSRI. GYANENDRA PRASADSRI. N. RAMA RAOSRI. S.N. MURTHY RAJUSRI. Y.S.SHANKARSRI. M.A.SAJID KHANMRS. C.V.SREELATHASRI. M.ANNAJI RAOSRI. V.KARUNAKARSRI. C.NARSING RAOSRI. N.SHASHIKUMARMRS.SAYEEDA NASEEM BANUMRS. T.ANNAPURNASRI. M.S. MURTHYSRI. NEERAJ KUMARSRI. V. BASAVARAJUSRI. B. RAJENDER KUMARSRI. B.C. SRINIVASSRI. N. ANANDSRI. RAVI RAJALINGAM

SENIOR STENO (ACP)SRI. G.B.S. MURTHYSRI. V. NAGAMUNISRI. T. JAYARAJSRI. M. SUBBA RAOSRI. D.V.V.R.K. ACHARYULUSRI. V.V. RAMANA RAOSRI. A.V. SRIHARIMS. V. USHA

SENIOR STENOSRI. I. JITHAMANMADHA RAOSRI. V. MOHAN RAOMRS. Y. SUJATHASRI. A. NAGESWARA RAOMRS. N.N.S.S.V.B.T. SUNDARISRI. B. GNANESHWARSRI. ABDUL HAFEEZMRS. Y. MADHAVIMRS. M. SAROJAMRS. K. SESHALAKSHMIMRS. M.S. SHASHIKALAMRS. P. HARATHI JAWAHARSRI. Y. MURALIKRISHNAMRS. N. SANJEEVA RANIMRS. V. JAISHI RANISRI. R.R. YADU KRISHNAMRS. M. SARITHA KUMARISRI. N.K. NAVEEN KUMARMRS. D. SHAMANTHASRI. D. KRISHNARAO

ASSISTANT GR II(GEN. / F&A/S&P)SRI. VEERA PRAKASHSRI. T.N. PRADHANSRI. Y.V. RAMESHSRI. M. NARSING RAOMRS. B. KOTESHWARISRI. R. SHESHI KUMARMRS. S.PRABHAVATHIMRS. C.S.GEETHAMRS. T.S. INDIRAMRS. D.VENKATA LAKSHMIMRS. S.HUSN AFROZESRI. P. RATAN RAJSRI. C. NATARAJUMRS. G.V.LAKSHMIMRS. A.UMA DEVI

111

SRI. S. KRISHNAIAHSRI. P.SHANKERSRI. K.YADAIAHSRI. S.SHUJATH HUSSAINMS. D.UMA MAHESHWARISRI. K. SUDHAKARSRI. MOHD. ABDUL ZAFFARSRI. V.S.N. MURTHYMRS. S. SAI BHAVANIMRS. C. ANNAPURNA

ASSISTANT GR III(GEN. / F&A/S&P)SRI. C. SATYASEELANSRI. A. VENKATESWARA RAOSRI. A. SHIV SHANKARMISS. SUNITA DEVISRI. VINCENT THOMASMRS. J. SARASWATHIMRS. R.A. KALAIMATHIMS. J. LATHASRI. V.GANESHSRI. M. NAGA RAJU

JUNIOR STENOMRS. N. LAKSHMI SUNITHAMISS. K.L. KAVITHASRI. G. SAINADHSRI. SHIV SHANKAR KUMARSRI.S. REVATHI KUMARMS. T. RAMA DEVI

SECURITY ASSISTANT GR. VIISRI. P. SUDERSAN

RECEPTIONISTMS. USHA A.

SECURITY ASSISTANT GR. IISRI. K. VEERAIAHSRI. LAXMAIAH / MALLAIAHSRI. K. YADAIAH / LAXMAIAH

COOK (GUEST HOUSE)SRI. P. SHASHI NAIRSRI. M. MOHAN RAO

RECORD KEEPERSRI. L.B. SURYA PRAKASH

SECURITY GUARD (ACP)SRI. PREM SINGHSRI. M.D. KHALID ALI

SECURITY GUARDSRI BH.V.GOPALKRISHNASRI. P. APPA RAOSRI. T. S. NEEDHISRI. M. MADANSRI. D. SHIVARAMUDUSRI K. NARSINGAPPASRI. T. KRUPPAIAHSRI. P.S. PANICKERSRI. A. BAL NARSIMHASRI. B. CHINNASRI. PRASAD LIMBOSRI. K. SOMI NAIDUSRI. G. MADHAVA REDDYSRI. M. BALARAJUSRI. T. VENKAT RAOSRI. D. JAMES PAULSRI. S. TRINADHA RAOSRI. P. ANANDA RAOSRI. K.P. THAPA

OTHER STAFFMS. Y. LAKSHMI DEVIMS. ASGHARI BANUSRI. G. CHANDRASHEKARMS. SUNDARI KAURMS. B. KALPANASRI. MD. YOUSUF/ISMAIL KHANSRI. SHAIK ISMAIL/ AFZALSRI. K. RAMESHMS. POCHAMMA / K. YADAIAHSRI. MIR MUMTAZ ALISRI. S. CHITTAIAHMRS. K.C. YESUPADAMMAMRS. J. LAXMIMRS. RENI BAIMS. SYEEDA SIRAJUNNISA BEGUMSRI. GHULAM TAHERSRI. RAZAK ALI/SADIQ ALI

MRS. U. SATYAMMASRI. P. VENKATESHAMSRI. P. KRISHNASRI. HAFEEZSRI. P. SANGEETA RAOSRI. SHAIK JAHANGIRSRI. J. LEWISMRS. S. SWARNALATHASRI. PARUSHAIAHMRS. A. SHASHIKALASRI. M. NARSIMHA S/O MUTHIAHSRI. R. NARSIMHA S/O R. SWAMYSRI. D. LAXMAIAHMS. M. DEVAMMAMS. P. RAMULAMMAMRS. R. LAXMI W/O SUDARSANMRS. S. POCHAMMA W/O S.SRI. MALLESHMRS. P. RENUKA W/O P.N. KUMARMRS. P. LAXMI W/O T.B. NARASIMHAMRS. M. LAXMAMMA W/O RAMULUSRI RAMULU S/O SARAVAIAHSRI. O. LAXMAIAH S/O LACHAIAHMRS. G. VENKATAMMASRI. A. VENKANNASRI. D. MANKIAHSRI. N. KRISHNAMS. P. YADAMMAMS. CH. NARSAMMASRI. PANDARISRI. NARSING RAO C.K.SRI. VENKATESHSRI. M. SURYANARAYANASRI. B. MAHENDERSRI. B. SURESH KUMARSRI. P. RAJAIAHSRI. K. VAMAN RAOSRI. K. SATYANARAYANASRI. M. DASARATHSRI. NARENDAR. VSRI. BALAIAH MMS. NAGAMANI. CSRI. SHABUDDIN MD.

Staff as on 01/04/2005

112

DISTINGUISHED OVERSEAS VISITORSDISTINGUISHED OVERSEAS VISITORSDISTINGUISHED OVERSEAS VISITORSDISTINGUISHED OVERSEAS VISITORSDISTINGUISHED OVERSEAS VISITORS

2004-052004-052004-052004-052004-05

Dr Bong Yong Lee, Chief Scientific Officer and

Dr S J Choi, from Daewoong Pharmaceutical Co,

South Korea

Dr Craig M Knight, Regional Business Manager

from Eastman Chemical Co, USA

Dr Wang Jin Xu, General Manager and Dr Serene

Ong, Business Development Executive from

NIPSEA Technologies, Singapore

Dr Inder Jaggi, CEO from Novakos Corporation,

USA

Business Delegations from:

DOW Chemical International, USA

Shiziazhung Pharamaceutical Co, Singapore

Atlanta Pharma Pvt Ltd

Innocentive, USA

VCCS Sdn Bhd, Malayasia

D&O pharmachem, USA

Strem Chemicals, USA

2003-042003-042003-042003-042003-04

Strem Chemicals, USA

Dr George Fraser, Head, Fragrance Research

from Givuadan, Switzerland

Dr Masami, Inada, President, Aisin Cosmos R&D

Co Ltd., Japan

Business Delegations from:

Merck, USA

Uquifa, Spain

PPG Inc.,. USA

P&G, USA

Kansai Paints, Japan

Honeywell Specialities, USA

Atlanta, USA

Eastman Chemical Co, USA

Eli Lilly, USA

Prof. Shirakawa, Nobel Laureate from Japan (Centre) is seenwith Dr. J.S. Yadav, Director

Director IICT (left) with members of the French Delegation

Director IICT is presenting a plaque to a Pakistan Scientistwho visited IICT.

114

Blank

115

Aisin Cosmos R&D Co Ltd, Japan New functional materials

Glaxo SmithKline Beecham, UK High throughput synthesis

Confluent Surgicals, USA Drug delivery

Givaudan, Switzerland New Processes

DuPont, USA Focussed compound library Development

Kansai Paints, Japan Process for photo acid generator

NATIONAL PROJECTS

Ministry of Agriculture, New Delhi PHT in oilseeds & pulses

NMITLI, CSIR, New Delhi Functionalization of alkanes

Ministry of Science & Technology, New Delhi Field evaluation & demonstration of

pheromones

NMITLI, CSIR, New Delhi Dicarboxylic acids

Directorate of Rice Research (ICAR), Genetic enhancement of aromatic short

Hyderabad grain rice for higher productivity & export

Neuland Laboratories Ltd., Hyderabad Process knowhow for methane

sulfonic acid frommercaptan

effluent generated in Ranitidine

Manufacture

DBT, New Delhi Field evaluation of pheromones

demonstration

Ministry of Health & Family Welfare, Use of modern technology &

New Delhi biotechnology in Ayurveda, Siddha,

Unani & Homeopathy drugs development

Muez-Hest Process Technologies (P) Ltd., Enzymatic degumming & dewaxing of

Mumbai/Ramcharan Oil Industries, Hyd. rice bran oil

Muez-Hest/Process Technologies, Mumbai/ Enzymatic degumming & dewaxing of

Bhatinda Chemicals Ltd., Bhatinda. rice bran oil

Mecpro Heavy Engg. Ltd. N. Delhi/Saraiwala Agro Enzymatic degumming & dewaxing of

Refineries Limited, Hyderabad rice bran oil

NEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKENNEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKENNEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKENNEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKENNEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKEN(2003-05)(2003-05)(2003-05)(2003-05)(2003-05)

OVERSEAS PROJECTSPARTY PROJECT

NEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKENNEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKENNEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKENNEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKENNEW CONTRACTS SIGNED/ASSIGNMENTS UNDERTAKEN

116


Mectech Process Engg. Pvt. Ltd, New Delhi Enzymatic degumming & dewaxing of

rice bran oil

Anu’s Laboratories, Hyderabad Process route optimization for 4

intermediates

Isaagro (Asia) Agro Chemicals Pvt. Ltd., Field trial efficiency of Elofenprox 20%

Mumbai W/P on larva & adult A. Stephensi

Bharat Electronics Ltd, Bangalore Detoxification & neutralization of various

gas cylinders of BEL at Bangalore

KCP Biotech Ltd. Hyderabad Engg. services for setting up a

commercial plant to manufacture

turmeric, chillies & annatto

United Insurance Ltd., Hyderabad Chemical report on fire accident of M/s

Roopa Industries Ltd.

Precision Electronic Components Mfg. Co. Providing assistance in developing the

Hyderabad fire retardant coatings

DRDL, Hyderabad Special Grade Epoxy Novalac system

suitable for canister (PJ-10) application

Rajshree Sugars & Chemicals Ltd, Development of process knowhow for

Coimbatore two pheromone Chemicals

Sami Labs Ltd, Bangalore Development of process knowhow for

Solanesol (98%) Decaprenol & Co-

Enzyme Q-10

Alfa Laval (India) Ltd, Pune / Sarda Agro Oils Ltd Enzymatic degumming & dewaxing of

rice bran oil

Mecpro Heavy Engg. Ltd., New Delhi/ Enzymatic degumming & dewaxing

AP Organic Oils Pvt. Ltd, of rice bran oil

Mittal Musli Farms & Research Centre, Characterization of extract of safed

Hyderabad musli

Balmer & Lawrie Ltd, Chennai Consultancy on R&D aspects of

Lipid Science &Tech projects of interest

PARTY PROJECT

117

Hindustan Reserch Centre, Mumbai Collection of explosion on tests data for

the given 5 samples

The Andhra Sugars Ltd, Kovvur REIA study for the construction of

secured land fill at mercury based caustic

soda plant

HAL, Bangalore Supply of low loss polyster resin &

benzoyl peroxide

Navin Fluorine Industries Ltd, Mumbai Process knowhow for 2,2,2-Trifluoro

Ethanol on lab scale

Saket Biotechnologies Ltd, Hyderabad Exploratory studies for novel drug

delivery system for newer moiety

The Andhra sugars Ltd, Kovvur Risk analysis of HAZOP study of UDMH

plant at Tanuku, AP

Nicholas Piramal India Ltd, Hyderabad Process knowhow for coenzyme Q-10

Glamptech Agro Process Pvt. Ltd, Mumbai Process knowhow for enzymatic

degumming & dewaxing of rice bran oil

Tripura Biotech Ltd., Hyderabad Development of process knowhow

for five products

Novozymes South Asia (P) Ltd, Preparation of trans-free vanaspathi

using enzymatic interesterification of

vegetable mixture

Hermes Chemicals Co. Pvt. Ltd, Secunderabad Samples of Toprimate

Kiran Adhesives & Chemicals, Adhesives for automatic labeling

Hyderabad machines

Godavari Sugar Mills Ltd., Mumbai Biocrystal demonstration on 20,000 KL

reactor

K N Agri Biotech, Hyderabad Biocompatible polymer membrane for

control release applications

DST, New Delhi Implementation of Indo-South African

Joint Project

PARTY PROJECT

New Contracts Signed/Assignments Undertaken

118


Bharat Rasayan Ltd, New Delhi Licensing of knowhow for Esfenvalerate (tech)

Vinati Organics Ltd, Mumbai Value addition for N-butylbenzene by

preparation of four intermediates

Krebb’s Biochemicals Ltd, Hyderabad Preparation and providing 5 gms sample

of Dihydro Lovastin

DST, New Delhi Synthesis and development of new

biodegradable and biocompatible

Polymers for tissue contacting

applications

Rhizome Distilleries (P) Ltd, Hyderabad Establising and validating QC Laboratory

Biological (E) Ltd., Hyderabad Acute, Sub-acute chronic toxicity

studies of haemophiles type-b conjugate vaccine

in different animal model

Centre for Excellence in Polymer Science, Fabrication of membranes for conducting

Karnataka University, Dharwad R&D Studies in speciality, organic

coatings and polymer areas

Hindustan Lever Ltd, Mumbai SEP-Box service charges for analysis of

client samples

Ganapathi Solvex (P) Ltd, Process knowhow for enzymatic

degumming and dewaxing of rice bran oil

Bagaria Agro Products, Aurangabad Process knowhow for enzymatic

degumming and dewaxing of rice bran oil

Jubiliant Organosys Ltd, Mysore AZM project work

Amchem Products Ltd, Noida Accelerating weathering test and salt

spray client

Jayshree Industries (P) Ltd, Chhattisgarh/ Process knowhow for enzymatic

Mecpro Heavy Engg. Ltd, New Delhi degumming and dewaxing of rice bran oil

PARTY PROJECT

119

TMOP & M, New Delhi Pilot plant scale process for biodiesel

from high FFA vegetable oils and acid oil

TMOP & M, New Delhi Controlled release polymer devices for

pest management in groundnut storage

TMOP & M, New Delhi Cyclodextrines as sensors

Balmer Lawrie & Co Ltd, Chennai Process knowhow for two formulations

equivalent to a) B 101 high performance

Ratiquor and (b) B 102 a premiumsegment

fish oil Ratiquor

DBT/CSIR-IICT & Govt. of AP Biotechnology Incubator Centre

Rajshree Sugars & Chemicals Ltd, Synthesizing & providing 200 gms of

Coimbatore pheromone mixture

Indigene Pharmaceuticals Pvt. Ltd, Development of novel bioactive

Hyderabad from plant materials & extracts in the

therapeutic molecules area of anti

cancer drugs

Gland Pharma Ltd., Hyderabad To provide R&D solutions in NMR

techniques

CFEES (DRDO), New Delhi Development of process knowhow for

Hepta fluoropropane

AP Pollution Control Board, Hyderabad Study on water consumption and waste

water generation in M/s. Mahalaxmi Text-

Prints Pvt. Ltd., Madanapally (V), R.R.

Dist.

PEG Consultants & Engineers Pvt. Ltd, Process knowhow for enzymatic

Mumbai degumming and dewaxing of rice bran oil

on 50 TPD scale

BHEL, Hyderabad Engineering of base frame & mechanic

mounted piping for industrial turbines

NIMITLI/CSIR, New Delhi Development of Novel fungicides

PARTY PROJECT


120


SMS pharmaceuticals Ltd, Hyderabad Development of process knowhow for

two intermediates : a) Diltiazem HCl by

asymmetric syntresis and b) Taxol C-13

side chain (API Intermediate)

Central Silk Board, Bangalore Studies on utilization of Erisilk worm

pupae by extraction of oil from pupae

and prepupae

Central Silk Board, Bangalore Studies on utilization of Erisilk

worm pupae by extraction of surface

waxes from pupae and prepupae

Zenenpep Biotechnologies, Hyderabad Toxicological studies on efficacy and

safety in vivo experiments on their

proprietary peptide molecule

used for treatment of wounds and burns

INGA Pharmaceuticals, Mumbai Synthesis of R-S-Noscapine

The Andhra Sugars Ltd, AP To conduct studies on improvement of

aspirin reaction and plant

Tarak Chemicals Pvt. Ltd., Gujarat Development of zinc di acrylate

NOCIL, Mumbai Development of process and suitable

catalyst for reaction of Aniline with Para-

Nitro-Chlorobenzene (PNCB) to give 4-

Nitro-Diphenylamine (4NDPA)

and subsequent reduction to 4-Amino

diphenylamine (4-ADPA) (99.8% purity)

Tribal Welfare Dept., Hyderabad Protection of community & traditional

knowledge relating to plants and

medicines with STs of AP

DST /IICT/ Virchow Chemicals Ltd, First preclinical investigation in India on Hyderabad

non viral gene therapy of chronic wounds

DST /IICT/ Indian Medicines & Quality assurance and validation of some

Pharmaceutical Corporation Ltd, Mohan ayurvedic formulations for lifestyle related

and gyneacological disorders

PARTY PROJECT

121

DART Manufacturing Co. Ltd, Hyderabad Identification of fungus attacking product

& suggestion of suitable remedial measures

CMPDI, Ranchi Direct sourcing of coal for value added

Chemicals

Rayudu Laboratories (P) Ltd, Hyderabad Technology for Indelible ink

Recon Oil Industries (P) Ltd, Mumbai Evaluation of blended edible oils

The Andhra Sugars Ltd, Kovvur, AP To prepare REIA report for the

conversion of mercury cell membrane

technology for caustic potash product

Apothecaries Ltd, New Delhi Method development for the quantisation

of Acomprosate in plasma samples

RR Industries, Hyderabad To carry out paint erosion test as per MIL

specifications of two pair of paint samples

Reliance Life Sciences (P) Ltd, Mumbai Providing pilot plant facilities and

technical services

Virchow Chemicals Ltd, Hyderabad Evaluation & certification of waste water

recycling system in the production of

Acetyl Phanilyl Chloride

Siva Kishore Sevashram, Tenali. Solvent solution for manufacture of wool

polish

Bhagiradha Chemicals, Hyderabad Standardization of impurities in

chlorpyriphos technical

MSPL, Hospet To fire the given samples at 1350oC,

1450oC and 1500oC

Satyam Computer Services Ltd, Hyderabad Providing technical consultancy and

undertaking analytical and testing

services for evaluation of samples

Bharat Rasayan Ltd, New Delhi Demonstration of Esfenvalerate (Tech.)

process on 50 gm scale

Virchow Chemicals Ltd, Hyderabad Licensing of Esfenvalerate (Tech.) on

scale of 2 Kg product

PARTY PROJECT


122


Mythri Agro Industries, Kerala Process knowhow for biopesticide

formulations from neem seeds/kernels

AP Geeta Parsramika Sahakara Arthik Spray drying of Neera sample

Sankshema Samstha, Hyderabad

Vishnu chemicals (P) Ltd, Hyderabad Utilizing facilities at Pilot Plant-II

Saraca Laboratories Ltd, Hyderabad Utilizing facilities at Pilot Plant-II

Oil & Natural Gas Corporation Ltd, Reliability study of critical control and

Institute of Engineering and Ocean safety system

Technology, Mumbai

Oil & Natural Gas Corporation Ltd, Development of failure frequency data

Institute of Engineering and Ocean base for ONGC offshore process

Technology, Mumbai equipment

DBT, New Delhi Hydrogen production by anaerobic

treatment process from effluents

Ministry of Information Technology, New Delhi Development of an integrated information

system for the control of Bancroftian

filariasis in Andhra Pradesh

DST, New Delhi Control of Malaria through Integrated

Information Technology tools in

Arunachal Pradesh

DBT, New Delhi Integrated control of Filariasis and

Malaria through Decision Support

System (BTIS network programme)

in Andhra Pradesh

DST, New Delhi Super capacitors based on conducting

polymers – An energy storage device

DST, New Delhi Standardization of hi-frequency plant

regeneration from different explants of

Chlorophytum borivilianum, an important

medicinal plant of India

TMOP&M, New Delhi Post harvest protection of maize from

pests and diseases in Southern India

PARTY PROJECT

123

CMPDI, Ranchi Direct sourcing of coal for value added

chemicals (in collaboration with CFRI)

DST, New Delhi Enzyme mediated resolutions and

deracemizations in ionic liquids

MNES, New Delhi Solar hydrogen production from water for

fuel cell

DST, New Delhi Boyscot fellowship programme in the

area of hetero-geneous catalysis to be

held at Lehigh University, Bethlehem,

Pennsylvania, USA for a duration of 12

months

Rajashree Sugars Ltd, Process for pheromone chemicals used

Coimbatore in IPM for sugarcane crop pests

Anu’s Laboratories Ltd, Process for 4-Vinyl aniline

Hyderabad

Shri Arihant Petrochem (P) Ltd, Process knowhow for Hydrogenation of

Bangalore crude rice bran wax

Abhay Solvents (P) Ltd, Knowhow for enzymatic process for

Koppal, Karnataka degumming of rice bran oil

Kamal Solvent Extractions (P) Knowhow for enzymatic process for

Ltd., Rajnandgaon degumming of rice bran oil

Chemical Construction

International Pvt. New Delhi (Project Engg. Co.)

Jay Shree Solvex (I) Pvt. Ltd, Durg, Chhattishgarh Knowhow for enzymatic process for degumming

Mecpro Heavy Engg. Ltd., New Delhi of rice bran oil

(Project Engg. Co.)

SMS Pharmaceuticals Ltd, PC based real time process control

Hyderabad technology for automation & control of

NMSM (Ranitidine Intermediate)

formation reactor of Ranitidine

production process

PARTY PROJECT


124


The Godavari Sugar Mills Ltd, Sameerwadi Alcohol production using free yeast and

yeast crystals in modified bioreactor

VSSC, Trivandrum Synthesis of computational design of

macrocyclic ligands on process for

separation of hafnium from

zirconium tailings by molecular

recognition technology

Consolidated Fibres, Kolkata Extraction of impurity-free sodium

thiocyanate (Nanofiltration Technology)

Vinati Organics Ltd, Mumbai Process for one-pot conversin of N-

Butylbenzene (NBB) (92%) a

byproduct to value added intermediate 1-

phenyl butalamine (PBA) (98%)

Sanmar Speciality Chemicals Ltd., Bench-scale process for Hydrazine

Chennai Hydrate (ketazine route)

Dabur Research Foundation, New Anti-cancer compounds synthesis

Ghaziabad

NMITLI, CSIR, New Delhi HERBOPRINT – Chromatographic

fingerprinting of herbal based

preparations for degenerative

disorders

NMITLI, CSIR, New Delhi A novel chromatographic finger printing

method for chemical and therapeutic

standardization of food

IFCPAR (Indo-French Novel synthetic methodologies in

Cooperation), New Delhi combinatorial chemistry for the

preparation of bioactive molecules

VSSC, Tiruvananthapuram Preparation of 4,4’-methylene bis

Kerela (cyclohexylamine) – a solid propellant

generated from 4,4’-metylene-dianiline

(MDA)

PARTY PROJECT

125

IFCPAR (Indo-French Development of toxic water pollution by

Cooperation), New Delhi advanced oxidation process.

Gas Authority of India Ltd, New Delhi Pre-commercialization studies of ANG

technology

Aeronautical Development Synthesis & development of cyanate

Authority, Bangalore ester based resins for advanced aircraft

applications

Indian Oil Corporation, The possible ill-effects over exposure of

Faridabad population to exhaust emission

Mittal Musli Farm & Research Subacute toxicity study of safed musli in

& Swiss Centre, Maharashtra wistar rats mice

Tablets India Ltd, Chennai Evaluation of DSA-5 for antidiabetic

activity in rats

Relisys Medical Devices Ltd, Estimatin on paclitaxel release from

Hyderabad coated stents

Lyka Labs Ltd, Mumbai Rabeprazole injection-A 14 day

intravenoustoxicity study in mice and rats

Kolhapur Municipal Corporation, Biological control of water hyacinth at

Maharashtra Rankala, lake

SPIC, Tuticorin Engineering design for 500 TPA

pyrazinamide plant

Pidilite Industries Knowhow on bench scale process for

Mumbai hydroxy ethyl cellulose

DBT, New Delhi Development of high performance

biological fluidized reactor for anti-biotic

production

Gas Authority of India Ltd, New Delhi Setting up natural gas laboratory

Natco Pharma Ltd, Hyderabad Development of pilot level anerobic

reactor for the Treatment of

pharmaceutical waste

PARTY PROJECT


126


MNES, New Delhi Advanced Biomass Gasification

IFCPAR, New Delhi (Indo- Novel synthetic methodologies in French

collaboration project) combinatorial chemistry for the

preparation of bioactive molecules

libraries

Dart Manufacturing (P) Ltd, Designing novel liposomal gene delivery

Hyderabad reagents & investigating the

role of size & surface change of lipid-DNA

V Life Sciences Technologies Anti-inflammatory potential of synthetic

Pvt. Ltd., Pune compounds in rat paw edema model

DST, New Delhi Design, Synthesis & evaluation of

NonlinearOptical Properties of New

DelhiNovel Organic & Metalic Molecular

Materials

MSN Laboratories Ltd, Sub-acute Toxicity study of Ezetimibe

Hyderabad and Resuvastatin calcium in Mice and

Rats

DBT, New Delhi Production of Alkaline Proteases by using

Immobilized Bacillus Licheniformis in

stirred tank and zed bed Reactors

DST, New Delhi Signal Chemicals in Plants during

Nodulation

DST, New Delhi Process and product standardization of

classical ayurvedic drugs with special

reference to rheumatism

DST, New Delhi Designing novel liposomal gene delivery

reagents & investigating the role of size &

surface change of lipid-DNA complex in

liposomal gene delivery

PARTY PROJECT

127

X-Ray Studies on Drug Molecules for Industries

Sandoz Pvt. Ltd, Thane

Matrix Laboratories Ltd, Hyderabad

Jubiliant Organosys Ltd, Mysore

Torrent Pharmaceuticals Ltd, Gujarat

Lupin Ltd., Pune

IPCA Laboratories Ltd., Mumbai

USV Ltd., Mumbai

Cadila Pharmaceuticals Ltd., Ahmedabad

Ind-Swift Laboratories Ltd., Bhagwanpur

(Punjab)

Dabur Research Foundation Ltd., Ghaziabad

(UP)

Emcure Pharmaceuticals Ltd., Pune

Hazop, Risk and EIA Studies for industries

Bayer India Ltd, Mumbai

Wonder Gas India Ltd, Hyderabad

United Chemicals, Hyderabad

Ana Bond India, Chennai

Bharth Petroleum Corporation Ltd, Chennai

Indian Oil Corporation Ltd, Ahmedabad

Hindustan Lever Research Centre, Mumbai

Andhra Sugars Ltd, Tanuku, AP

Hindustan Petroleum Corporation Ltd,

Visakhapatnam

Ministry of Environment and Forests, New Delhi

IBB Co. Ltd, Cherlapally, Hyderabad

Coromandel Fertilizers Ltd, Visakhapatnam

Advisory Consutancy Services rendered to industry:

Dabur India Ltd, Ghaziabad, UP

Balmer & Lawrie Co. Ltd., Chennai

Alkali Metals Ltd, Hyderabad

AVRA Laboratories (P) Limited, Hyderabad

Indigene Pharaceuticals Ltd, Hyderabad

Indus Biosciences (P) Ltd, Hyderabad

Gland Pharma Ltd, Hyderabad

Max Bond, Bangalore

USV Ltd, Mumbai

Bezwada Biomedical Co. Ltd, Secunderabad

Ogene Systems India (P) Ltd, Hyderabad

Supreme Chemical Ventures (P) Ltd, Hyderabad

Rallis India Ltd, Rallis Research Centre, Bangalore

Alchem International Ltd, New Delhi

Orchid Chemicals & Pharmaceuticals Ltd, Chennai

Ashian Herbex Ltd, Hyderabad

Sai Life Sciences Ltd, Hyderabad

Vishnu Chemicals Pvt. Ltd, Hyderabad

Biological (E) Ltd, Hyderabad

Sarracca Labs (P) Ltd, Hyderabad


Exchange of agreement with M/S. SMS Pharmaceuticals,

Hyderabad.

Natural colour extraction plant of M/S. KCP Biotech, Hyderabad.

128

TECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATED

Rajashree Sugars Ltd, Process for Pheromone chemicals used in IPM for

Coimbatore sugarcane crop pests

Neuland Labs Ltd, Hyderabad Process knowhow for the conversion of methyl

mercaptan, an effluent gas, to a value added

product (methane sulphoic acid)

Anu’s Laboratories Ltd, Process for 4-Vinyl aniline

Hyderabad

Shri Arihant Petrochem (P) Ltd, Process knowhow for Hydrogenation of Crude

Bangalore Rice Bran wax

Abhay Solvents (P) Ltd, Process for enzymatic process for degumming

Koppal, Karnataka of rice bran oil on 50 TPD

Saraiwala Agro Refineries Process for enzymatic process for degumming

Ltd, Hyderabad of rice bran oil on 50 TPD

Ramacharan Oil Industries, Process for enzymatic process for degumming

Hyderabad of rice Bran oil on 50 TPD

Kamal Solvent Extractions (P) Process for enzymatic process for degumming

Ltd., Rajnandgaon of rice bran oil on 50 TPD

AP Organics Pvt Ltd, Dhuri, Process for enzymatic process for degumming

Punjab of rice bran oil on 50 TPD

Jay Shree Solvex (I) Pvt. Ltd, Process for enzymatic process for degumming

Durg, Chattishgarh of rice bran oil on 50 TPD

SMS Pharmaceuticals Ltd, PC based real time process control technology for

Hyderabad automation & control of NMSM (Ranitidine

Intermediate) formation Reactor of Ranitidine

production process

The Godavari Sugar Mills Ltd, Alcohol production using free yeast and yeast

Sameerwadi crystals in modified bioreactor

Vinati Organics Ltd, Mumbai Process for one-pot conversion of N-Butylbenzene

(NBB) (92%) a byproduct to value added

intermediate 1-phenyl butalamine (PBA) (98%)

TECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATED2003-042003-042003-042003-042003-04

PARTY PROJECT

129

TECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATEDTECHNOLOGIES / PROCESSES DEMONSTRATED2004-052004-052004-052004-052004-05

PARTY PROJECT

Sarda Agro Oils Ltd., Pune Process for enzymatic degumming anddewaxing of rice bran oil on 50 TPD

S.S.D. Oil Mills Co. Ltd., Process for enzymatic degumming andChennai dewaxing of rice bran oil on 50 TPD.

VSSC, Trivandrum Synthesis of computational design ofmacrocyclic ligands on process for separation ofHafnium from zirconium tailings by molecularrecognition technology

Consolidated Fibres, Kolkata Extraction of impurity-free sodium Thiocyanate(Nanofiltration Technology)

Navin Fluorine Industries 2,2,2-TrifluoroethanolMumbai

SRF Ltd, New Delhi Pilot plant process on HFC-134a

Navin Fluorine Industries, Pilot plant process on HFC-134aMumbai

Sanmar Speciality Chemicals Ltd., Bench-scale process for Hydrazine HydrateChennai (ketazine route)

Dabur Research Foundation, New Anti-cancer compounds synthesisGhaziabad

NMITLI, CSIR, New Delhi HERBOPRINT – Chromatographic fingerprintingof herbal based preparations for degenerativedisorders

NMITLI, CSIR, New Delhi A novel chromatographic finger printing methodfor chemical and therapeutic standardization offood

IFCPAR (Indo-French Novel synthetic methodologies in combi-Cooperation), New Delhi natorial chemistry for the preparation of bioactivemolecules

Bharat Rasayanik Chemicals Process knowhow for Esfenvalerate (chiralLtd., New Delhi synthetic pyrethroid)

TECHNOLOGIES / PROCESSES / REPORTS RELEASEDTECHNOLOGIES / PROCESSES / REPORTS RELEASEDTECHNOLOGIES / PROCESSES / REPORTS RELEASEDTECHNOLOGIES / PROCESSES / REPORTS RELEASEDTECHNOLOGIES / PROCESSES / REPORTS RELEASED2003-042003-042003-042003-042003-04

PARTY PROJECT

Technologies / Processes Demonstrated

130


PARTY PROJECT

Kansai Paints, Japan Process for photo acid generator

VSSC, Tiruvananthapuram Preparation of 4,4’-methylene bisKerela (cyclohexylamine) – a solid propellant generated

from 4,4’-metylene-dianiline (MDA)

IFCPAR (Indo-French Development of toxic water pollution byCooperation), New Delhi advanced oxidation process.

Gas Authority of India Ltd, Pre-commercialization studies of ANG (Adsorbed)New Delhi Natural Gas) technology

Aeronautical Development Synthesis & development of cyanate esterAuthority, Bangalore based resins for advanced aircraft applications

Indian Oil Corporation, The possible ill-effects over exposure ofFaridabad population to exhaust emission

Mittal Musli Farm & Research Subacute toxicity study of safed musli in wistarCentre, Maharashtra rats &mice

Tablets India Ltd, Chennai Evaluation of DSA-5 for antidiabetic activity inrats

Relisys Medical Devices Ltd, Estimatin on paclitaxel release from coatedHyderabad stents

Lyka Labs Ltd, Mumbai Rabeprazole injection-A 14 day intravenoustoxicity study in mice and rats

Kolhapur Municipal Corporation, Biological control of water hyacinth at RankalaMaharashtra lake

SPIC, Tuticorin Engineering design for 500 TPA pyrazinamideplant

Pidilite Industries, Mumbai Knowhow on bench scale process for hydroxyethyl cellulose

DBT, New Delhi Development of high performance biologicalfluidized reactor for anti-biotic production

Gas Authority of India Ltd, Setting up natural gas laboratoryNew Delhi

Natco Pharma Ltd, Hyderabad Development of pilot level anerobic reactor forthe Treatment of pharmaceutical waste

KCP Biotech, Hyderabad Detailed design report for 1 TPD (raw material)Commercial plant to manufacture turmeric,annatto and chilies

131

PARTY PROJECT

Saket Biotechnologies Process knowhow for a herbal cream for(P) Ltd., Hyderabad skin and cosmetic application

Kansai Paints, Japan Solder resist materials

MNES, New Delhi Development of a methanol reformer catalystfor 10 W fuel cell

DST, New Delhi Synthesis of carbohydrates based signalchemicals for nodulation (in plants)

DST, New Delhi Designing efficient non-lionear opticalorganic molecules “A quantum ChemicalApproach”

DST, New Delhi Role of highly polarized / charge transferexcited state-quantum chain isomerization

Technology Misson on Materials for positive photo resistsElectronics Materials (DOE)

Process Safety Center has undertaken and submitted the report on Risk Analysis and HAZOPstudies for following clients.

BPCL-Mumbai Risk Analysis of proposed LPG bottling plant ofBPCL

EPTRI-Hyderabad Multipath Risk Analysis of Break Linings Plant

IOCL-Ahmedabad Risk Analysis of Auto LPG dispensing system at IOCL,Vejalpur (Setelight) Ahmedabad

Wonder Gas India Limited, Risk Analysis of proposed hexane filling Station ofKondapally, A.P Wonder Gas India Ltd., Kondapally

Bayer India Limited, Consequence Analysis of Boilers, Rotary Klin,IncineratorThane, Mumbai and Aniline & Nitrogen Storages

Bharat Petroleum HAZOP Studies of proposed LPG transfer line fromCorporation Ltd., Hazira. ONGC to Bottling Plant of BPCL, Haziara , Surat.

BPCL, Chennai Risk Analysis of proposed LPG siding facility of BPCL,at Cherlapally

BPCL, Cherlapally, Risk Analysis of conversion of “FO” TO “HSD “StorageHyderabad and proposed MS, ATF, and Ethanol Storage Tanks of

BPCL, POL Depot at Cherlapally

Technologies/Processes / Reports Released

132


Bayer India Ltd., Consequence Analysis of PSCl3 Methyl Parathion,

Thane, Mumbai. Meta Systox-R, CTA & Thiosalt Reactors

The Andhra Sugars HAZOP Study and FTA, ETA of HTPB Plant atLimited, Tanuku, A.P. Tanuku

United Chemicals Risk analysis of proposed pesticides technical andHyderabad formulation plant at Indriyala (V), Pochampally (M),

Nalgonda Dist A.P.

IOCL-Cuddapah Damage contouring of identified hazardous scenariosfor LPG bottling plant, Cuddapah

BPCL-Cherlapally Risk Analysis and HAZAOP studies of proposedLPG siding facility at Cherlapally

Unilever Inida Limited, Explosion Study Of Soap- Ipa- H2O

2 Mixture

Mumbai

Unilever India Limited, Explosion Study Of Un-Op varnish in the mist form atMumbai elevated temperature

Ciba India Pvt. Ignition Temperature, DTA Open Cup And Gas EvolutionLimited, Mumbai Test For Irganox And 3-Methyl 4-Nitrophenol

Unilever India Explosion Study Of Chlorinated IsocyanuratesLimited, Mumbai at elevated temperatures

IOCL-Ahmedabad Risk Analysis of Auto-LPG filling system at IOCL,Gokulesh Petroleum, Narol, Ahmedabad

IOCL-Ahmedabad Risk Analysis of Auto-LPG dispensing system at IOCLGujarat Auto Centre, Usmanpura, Ahmedabad

IOCL-Ahmedabad Risk Analysis of Auto-LPG filling system at IOCL,Rashtriya Auto, Behrampur, Ahmedabad

IOCL-Ahmedabad Risk Analysis of Auto LPG filling system at IOCL,Sarda Petroleum Chandkheda, Gandhinagar

Bayer (India) Limited Consequence Analysis of Vulkanox 4688Thane, Mumbai Hydrogenation

IOCL-Bangalore Risk Analysis and HAZOP studies of LPG Bottling plant

SRAACL, Kurnool Safety Audit of Caustic Soda and Fatty Acid Divisionof Sree Rayalaseema Alkalies & Allied Chemicals Limited.

PARTY PROJECT

133

PARTY PROJECT

Navin Fluorine Industries, Pilot Plant process on HFC-134aMumbai

SRF Ltd, New Delhi Pilot Plant process on HFC-134a

MNES, New Delhi Advanced Biomass Gasification

IFCPAR, New Delhi - Novel synthetic methodologies in combinatorial(Indo French collaboration chemistry for the preparation of bioactiveproject) molecules libraries

Dart Manufacturing (P) Ltd, Identification of the fungus attacking the productHyderabad and suggestion of suitable remedial measures for

the control of the fungus

V Life Sciences Technologies Anti-inflammatory potential of syntheticPvt. Ltd., Pune compounds in rat paw edema model

DST, New Delhi Design, Synthesis & evaluation of NonlinearOptical Properties of Novel Organic & MetallicMolecular Materials

MSN Laboratories Ltd, Sub-acute Toxicity study of Ezetimibe andHyderabad Resuvastatin calcium in Mice and Rats

DBT, New Delhi Production of Alkaline Proteases by usingImmobilized Bacillus Licheniformis in stirred tankand zed bed Reactors

DST, New Delhi Signal Chemicals in Plants during Nodulation

DST, New Delhi Process and product standardization of classicalayurvedic drugs with special reference torheumatism

DBT, New Delhi Designing novel liposomal gene delivery reagents& investigating the role of size & surface changeof lipid-DNA complex in liposomal gene delivery

Process Safety Center has undertaken and submitted the report on Risk Analysis and HAZOPstudies for following clients..

Anabond Limited, Chennai Risk Analysis and HAZOP studies of ProposedPC

4 at Ezhichur Village, Sriperumbudur Taluk,

Chengalpattu Dist, Tamilnadu

Bayer (India) Limited, Hazard and Operability studies of NaMBT PlantThane, Mumbai

Technologies/Processes/Reports Released

134

PARTY PROJECT

BPCL, Bangalore Risk Analysis of Auto-LPG filling system atArunodaya filling station, Gangadhara Nagar,Bangalore

BPCL, Bangalore Risk Analysis of Auto-LPG dispensing system atChanders filling station, Gandhinagar, Bangalore.

BPCL, Bangalore Risk Analysis of Auto-LPG dispensing system atSankara Service station, Malleswaram,Bangalore.

M/s. I.T.C Limited, Paper Risk Analysis of LPG storage facilities at Sarapaka,Boards & Specialty Papers Khammam Dist.Division, Sec-bad.

IOCL, Ahmedabad Risk Analysis of Auto LPG dispensing station atM/s. Vijay Petroleum Retail outlet, Rakhial,Ahmedabad

The Andhra Sugars Limited, Risk Analysis of the proposed UH-25 Plant at TanukuTanuku

BASF India Limited Mangalore A Report on Evaluation of Safety Properties of theDyes/Colorants.

IOCL, Ahmedabad Risk Analysis of Auto-LPG dispensing station atM/s. Dhanalaxmi Petroleum, Vijaynagar,Ahmedabad.

IOCL, Ahmedabad Risk analysis of Auto-LPG dispensing station atM/s. Omkar Petroleum, Subhanpura, Vadodara.

IOCL, Ahmedabad Risk analysis of Auto-LPG dispensing station atM/s. Shreenathji Auto point, Amraiwadi,Ahmedabad.

BPCL, Cherlapally, Hyderabad. External Safety Audit of POL Depot Cherlapally

CIBA India Pvt.Ltd, Mumbai. DTA, Gas evolution & BAM Oven test Report

HPCL, Visakhapatnam Quantitative Risk Analysis of the field roomslocated in different process units (PRU-DHDS &FCCU-I(R)

BPCL, Cherlapally, Hyderabad Damage contours and basis of LPG leakage inLPG unloading Gantry at Cherlapally

ASL, Tanuku HAZOP studies of the proposed liquid Hydrogenplant at Saggonda


135

New a-glucosidase inhibitors and their synthesisfrom a natural source by J M Rao, R JagadeeshwarRao, U Sampath Kumar, S Venkat Reddy, A K Tiwari,J S Yadav, V Raghavan Patent US (1/4/03) dated10/403034

A novel method for chromatographic fingerprinting and standardization of single medicinesand formulations by D Vijaya Kumar, K V RaghavanYugoslavia Patent255/2003 (3/4/03), Korea (2/6/03), UAE (8/6/03) 178/2003

A process for the preparation of b-keto aliphaticacid ester useful as therapeutic agent by AnnapurnaJetty, D M Akkewar, K V Raghavan. Patent [PT-327]US (16/5/03) 10/439174 (Divisional)

An improved process for the pretreatment ofvegetable oils for physical refining by P P‘Chakrabarti, B V S K Rao, S K Roy, BLA PrabhavathiDevi, K N Prasanna Rani, V Vandana, C Kalyani, KGaddam, Vijay Kale, R B N Prasad Patent [PT-371]PCT (30/5/03) PCT/IN03/00203 US (30/5/03) 10/449698

A novel herbal composition for the treatment ofcancer by J M Rao, P V Srinivas, J S Yadav, K VRaghavan, A K Saxena, M Shanmugavel, H Kampasi,G N Qazi. Patent[PT-351] US (17/6/03) 10/463060(Divisional) India (6/11/03) 1837/DELNP/03

Improved process for the synthesis of calix (4)pyrroles over molecular sieve catalysts by K VRaghavan, S J Kulkarni, M Radha Kishan, N Srinivas.Patent[PT-306] US (29/7/03) 10/609151 France(25/8/03) 1915651.2 US (29/7/03) /609151France (25/8/03) 1915651.2

Enzymatic process for preparing reduced-caloriefats containing behenic acid by T N B Kaimal, SanjitKanjilal, R B N Prasad, Gafoorunnisa. Patent [PT-192] US (28/8/03) (Divisional)

A chemoenzymatic process for the steroselectivepreparation of both r and s enantiomers of 3-hydroxy-3-phenyl propanenitrile by Ahmed Kamal,G B Ramesh Khanna, M Venkateswar Rao, K VRaghavan. Patent [PT-300 ] GB (25/7/03)0317492.7 Japan (19/9/03) 2002-558527

An improved process for the enhancement of cycle-life of the zinc chromium based catalyst used inthe synthesis of 2-methylpyrazine by P S Saiprasad,K V Raghavan, P Kanta Rao, S J Kulkarni, K NarasimhaRao, R Gopinath, S Farsinavis, H M Meshram. Chinadated (27/9/03), Patent 01823096.2 Japan dated(29/9/03), Patent 2002-577798, Korea dated (29/9/03) Patent 2003-7012759, EP dated (29/9/03),Patent 01934298.9

An improved process for the synthesis of arylpyridine base over zeolite catalysts by S J Kulkarni,K V Raghavan, V Radha Rani, N Srinivas EP dated(29/9/03) Patent No. 1934301.1 Japan dated (29/9/03) Patent 2002-577788

Process for the preparation of 2-methyl 1,4- napthoquinone by S Narayanan, KVVSBSR Murthy, KMadhusudan Reddy, N Premchandar Japan dated(29/9/03) Patent 2002-577762 India dated (11/9/03)

An improved process for the synthesis ofoctahydro acridine (annulated pyridines) by S JKulkarni, K V Raghavan, V Radha Rani, N SrinivasPatent Japan (29/9/03) EP (29/9/03) 1934295.5

An improved process for the synthesis of porphyrincompounds over molecular sieve catalysts undermicrowave irradiation by S J Kulkarni, K V Raghavan,M Radha Kishan, N Srinivas. Japan (29/9/03) Patent2002-577829 EP (29/9/03) Patent 1932048

An improved process for the synthesis of aliphaticcyclic amines by S J Kulkarni, K V Raghavan, V RadhaRani, N Srinivas Japan (29/9/03) 2002-577787 EP(29/9/03) 1934304.5

Novel herbal composition for the treatment ofgastric ulcer by J M Rao, A K Tiwari, U SampathKumar, B S Sastry, J S Yadav, K V Raghavan, GautamPalit, D N Bhalla, Deepak Rai, P M Varier, T SMuraleedharan, K Muraleedharan

Process for simultaneous preparation ofnanocrystalline titanium dioxide and hydrazinemonohydrochloride by S V Manorama, KMadhusudana- Reddy, P Basak, C K Nisha, C V Gopal

Reddy US (13/11/03) 10/714290 PCT (20/11/03)PCT/IB03/05251 India (11/12/03) 1538/DEL/03

PATENTS FILED IN INDIA AND OVERSEASPATENTS FILED IN INDIA AND OVERSEASPATENTS FILED IN INDIA AND OVERSEASPATENTS FILED IN INDIA AND OVERSEASPATENTS FILED IN INDIA AND OVERSEAS

2003-04.2003-04.2003-04.2003-04.2003-04.

136


Process for the development of inexpensive,alternative, oxygen barrier material for the

packaging industry by K V S N Raju, K I Suresh, B S

Sitaramam, S Sridhar, Asad Ali Khan PCT (29/12/

03) PCT/IN03/00407 US (30/12/03) 10/747616India (27/2/04

Novel (2-fluoropyrrolo [2,1-c] [1,4] benzodiazepine

dimmers useful as anticancer agents by Ahmed

Kamal, P S Murali Mohan- Reddy, D Rajasekhar Reddy

US (31/12/03) PCT (31/12/03) PCT/IN03/00448

Tiruchenduramine and derivatives â-carboline

derived guanidine alkaloids as á-glucosidase

inhibitors by Y Venkateswarlu, K Ravinder, J S Yadav,

Y Sarath Kumar, S Ramakrishna, P V Diwan, J

Venkateswara Rao, P Ramesh, Hartmut Laatsch -

US (31/12/03) PCT (31/12/03) PCT/IN03/00444

Novel nonnatural c-linked carbo-b-peptides with

robust secondary structures by G V M Sharma, K

Ravinder Reddy, P Radha Krishna, A C Kunwar, A

Ravi Shankar, B Jagannadh, P Jayaprakash - India

(31/3/04) 641/DEL/04

New a-glucosidase inhibitors from a natural source

by J M Rao, P V Srinivas, V Anuradha, A K Tiwari,

Amtul Zehra Ali, J S Yadav, K V Raghavan - India

(27/2/04)

C8-linked pyrrol [2,1-C] [1,4] benzodia zepine -

Acridone Acridine Hybrids as Anti-Tumour Agents

by Ahmed Kamal, O Srinivas, P Ramulu, G Ramesh,

P Praveen Kumar - US (31/12/03) PCT (31/12/03)

PCT/IN03/00464

Substituted benzimidazoles linked to pyrrolo [2,1-

c] [1,4] benzodiazepines as anticancer agents by

Ahmed Kamal, P Ramulu, O Srinivas - US (31/12/

03) PCT (31/12/03) PCT/IN03/00462

A process for the preparation of substituted

dihyropyridinones using polyaniline salts as

catalysts by S Palaniappan, V J Rao, B Gangadasu -

US (31/12/03) PCT (31/12/03) PCT/IN03/00455 -India (20/2/04)

Pharmaceutical composition comprising (-)-

secoisolariciresinol by J M Rao, A K Tiwari, U

Sampath Kumar, J S Yadav, K V Raghavan - China

(20/1/04) Canada (22/1/04) Korea (26/1/04)

2004-7001130

(+)-cycloolivil as antioxidant obtained from natural source

namely stereospermum personatum by J M Rao, A K Tiwari,

U Sampath Kumar, J S Yadav, K V Raghavan - China (20/1/

04) 1823501.8 Canada (23/1/04)

(-)-olivil as antioxidant which is obtained from a

new natural source namely stereospermum

personatum by J M Rao, A K Tiwari, U Sampath

Kumar, J S Yadav, K V Raghavan - China (20/1/04)

Japan (26/1/04) 2003-516509 Korea (27/1/04)

2004-7001212.

Recovery of sodium thiocyanate from industrial

process solution by membrane based

nanofiltration technique by S Sridhar, G S Murthy,

D Suhanya, B Smitha, M Ramakrishna - US (29/3/04)

A process for the insitu synthesis of supported

ammonium salts of heteropolyacids by P S Sai

Prasad, K V Raghavan, I Suryanarayana, K

Narasimha Rao, Ch. Srilakshmi, M Santosh Kumar,

K Bhupal Reddy - Korea (31/3/04) Japan (31/3/

04) Korea (31/3/04) Japan (31/3/04) EP (31/3/04)

EP (31/3/04)

Synthesis of chiral furan aminoacids as novel

peptide building blocks by T K Chakraborty S

Tapadar - US (31/3/04)

New pyrimidine linked pyrrolo (2,1-c) (1,4)

benzodiazepines as potential antitumour agents

by Ahmed Kamal, K Laxma Reddy - India (29/5/03)

747/DEL/03

Partitioned batch reactor for improved production

of alcohol using immobilized yeast by R S

Prakasham, P N Sarma, J Joseph, M Ramakrishna,

Vedantachary, K V Raghavan - India (17/6/03) 810/

DEL/03

137

Novel cationic amphiphiles for intracellular delivery

of therapeutic molecules molecules its composition,

process and use thereof by M Bharat Kumar,

Arabinda Chaudhuri, Y Ramdas, N Madhusudana

Rao - India (11/9/2003)

Novel vitamin b12 - biodegradable micro particulate

conjugate carrier systems for peroral delivery of

injectable drugs, therapeutic peptides/ proteins

and vaccines by Kishore B Chalasani, P V Diwan, K V

Raghavan, G J Russell Jones, S K Jain, K Koteshwar

Rao - India (25/8/03)

A process for in-situ deposition of silver on

activated carbon by K S Rama Rao B David Raju, P

Venkateswar Rao, V Siva Kumar, A H Padmasri, K V

Raghavan - India (28/8/03)1055/DEL/03

Alkylxanthates and their use as a pesticides by J

Venkateswara Rao, Y Venkateswarlu, K V Raghavan

- India (24/9/03) 1530/DELNP/03

An improved process for the preparation of n-

phosphonomethyl glycine by D S Iyengar

P Neelakantan, B Vittal Rao, D Subhash Reddy, Sri

Kumaran Thamby, R Rangarajan, D K Kohil, B S

Makwana - India (30/9/03) 1223/DEL/03

A process for preparation of bioactive cationic

amphiphiles. by M Bharat Kumar Arabinda

Chaudhuri, Y Ramdas, N Madhusudana Rao - India

(6/11/03) 1836/DELNP/03

A novel method of standardization of chemical and

therapeutic values of foods and medicines and

pathological properties/conditions in biological

samples by chromatographic fingerprinting by D

Vijayakumar, K V Raghavan - India (28/1/04) 137/

DEL/04

A process for the in situ synthesis of supported

ammonium salts of heteropolyacids by P S Sai

Prasad, K V Raghavan, I Suryanarayana, K

Narasimha Rao, Ch. Srilakshmi, M Santosh Kumar, K

Bhupal Reddy (China)

A novel herbal composition for the treatment of

cancer by J Madhusudana Rao, P V Srinivas, J S Yadav,

K V Raghavan, A K Saxena, M Shanmugavel, H

Kampasi, G N Qazi (Canada, Korea, Japan).

A novel C6-substituted furanoid sugar amino acids

and improved process for preparing the same by T

K Chakraborty, G Sudhakar (India, US, PCT)

Process for preparing nanosized, thermally stable,

and high surface area multi-component metal

oxides by B Mahipal Reddy, Ataullah Khan, P M

Sreekanth, P Lakshmanan (India, US)

Pyrrolo [2,1-c][1,4] benzodiazepine-napthalimide

conjugates linked through piperazine moiety and

process for preparation thereof by Ahmed Kamal,

R Ramu, G B Ramesh Khanna (India, PCT, US)

Synthesis of chiral furan aminoacids as novel

peptide building blocks by T K Chakraborty,

Subhasish Tapadar (India, PCT)

Recovery of sodium thiocyanate from industrial

process solution by membrane based

nanofiltration technique by S Sridhar, G

Suryanarayana Murthy, D Suhanya, B Smitha, M

Ramakrishna (PCT).

Process for preparing (s)-alpha-cyano-3-

phenoxybenzyl-(s)-2-(4-chlorophenyl)-isovalerate

by V V Narayana Reddy, K Ishratullah, PV K Raju, T

Ramesh Babu, M Mahesh, C Venkateswara Reddy

2004-052004-052004-052004-052004-05

Patents Filed in India and Overseas during

138


An enantioconvergent chemoenzymatic synthesis

of ( R)-¡-amino-b- acid ((R)- GABOB) by Ahed Kamal,

G B Ramesh Khanna, T Krishnaji, R Ramu (US)

A catalytic process for simultaneous furfural

hydrogenation-cyclohexanol dehydrogenation in

vapor phase by K S Rama Rao, B David Raju, S

Narayanan, B M Nagaraja, A H Padmasri, V

Sivakumar, V Shashikala, P Seetharamulu, S S Reddy

(India, US)

Immobilized FR(III) over HY zeolite: An ecofriendly

photo-fenton catalyst by M Subrahmanyam, V

Durga Kumari, M Noorjahan (India, US, PCT)

An improved liquid phase process for the synthesis

of octahydroacridine and octahydrphenanthridine

(annulated pyridines) over molecular sieve catalyst.

by S J Kulkarni, KVV Krishna Mohan, N Narender, K V

Raghavan (India, PCT, US)

An improved method for adsorption and reduction

of hexavalent chromium. by G Parthasarathy, B

Sreedhar, B M Choudary (US)

A novel 1-(aryloxy) propionoyl -2-arylsulfonyl

hydrazines useful as hypoglycemic agents by T

Ramalingam, Y V D Nageswar, S Ramakrishna, A

Bhaskar Rao, P V Diwan, S Yadav, K V Raghavan

(India)

New 4b -1"-[2"-(substituted benzoyl anilino]

podophyllotoxin analogues useful as anti-cancer

agents by Ahmed Kamal, P S M Mohan Reddy

(India)

A process for racemisation of undesired optically

active isomer (R) –2(4- Chlorophynyl)-3-methyl

butanoic acid (R ) – CPMBA by V V Narayana Reddy,

K Ishratullah, P V K Raju, T Ramesh Babu, M Mahesh,

C Venkateswara Rao (India)

Process for the preparation of polyurethane polyol

from cardanol and rigid foams therefrom by K I

Suresh, V S Kishan Prasad (India, PCT, US)

A novel method for the evaluation of porphyrins,

calix(4) pyrroles and allied macrocyles over zeolite

backed tlc plates using high performance thin layer

chromatography(hptlc) under microwave

irradication by P Sita Devi, K V Raghavan, S J Kulkarni,

M Radha Kishan, V Radha Rani, MRVS Murthy (EP)

New pyrrolo[2,1-c][1,4] benzodiazepine-

anthraquinone conjugates useful as antitumour

agents by Ahmed Kamal, R Ramu, G B Ramesh

Khanna (India, US, PTC)

New herbal composition for treating gastric ulcer

by J Madhusudana Rao, U Kumar B S Sastry, J S

Yadav, K V Raghavan, Gautam Palit, Madhu Dikshit,

Deepak Rai, P M Varier, T S Muraleedharan, K

Muraleedharan (India, China, Canada, EP, JP)

An improved process for the pretreatment of

vegetable oils for physical refining by P P

Chakrabarti, BVSK Rao, S K Roy, BLA Prabhavathi

Devi, K N Prasanna Rani, V Vandana C Kalyani, K

Gaddam, Vijay Kale, R B N Prasad (Indonesia)

An improved process for the preparation of ethyl

2,3-dihydrobenzo [1,4] dioxin -2- carboxylate by M

Pardhasaradhi, G Kumaraswamy, A K Das, Nivedita

Jena, C J Snehalatha Nair (China, GB, Korea, Poland)

Naturally occurring coumarins and their precursors as

acetycholineesterase inhibitors by J Madhusudana Rao, B

Chinaraju, P V Srinivas, K S Babu, J S Yadav, K V Raghavan, H

K Singh Chandiswar Nath (US)

An improved process for the synthesis of novel

cationic amphiphiles for intracellular delivery of

therapeutic molecules by M Bharat Kumar,

Arabinda Chaudhuri, Y Ramadas, N M Rao (JP)

139

New pyrrolo [2,1-C] [1,4] benzodiazepines useful as

antitumour agents by Ahmed Kamal, P S M Mohan

Reddy (India)

New non-cross-linking pyrrollo [2,1-C] [1,4]

benzodiazepines useful as potential anti-cancer

agents by Ahmed Kamal, G Ramesh, O Srinivas, P

Ramulu (India)

New a-glucosidase inhibitors and their synthesis

from a natural source by J Madhusudana Rao, R

Jagadeeshwar Rao, U Sampath Kumar, S Venkat

Reddy, A K Tiwari, J S Yadav, K V Raghavan (India)

Inclusion complex of anti-tubercular rifampicin with

beta-cyclodextrin or 2-hydroxypropyl beta-

cyclodextrin and a process for producing the same.

by K Rama Rao N Bhanumathi, J S Yadav, N S

Krishnaveni (India)

Sequential batch reactor with technology with

biofilm configuration for treatment complex

chemical and pharmaceutical effluents by SVR

Venkata Mohan, P N Sarma, N Chandrasekhara Rao,

K Krishna Prasad, K V Raghavan (India)

A process for the preparation of 1,1,1,2-tetra

fluoroethane from 1,1-dichloro tetrafluoroethane

by S Narayan Reddy, P Shantan Rao, G Anuradha, B

Narsaiah Y Rambabu, PVSS Srinivas, K Ravindranath

(India)

An improved process for 2,2-dichloro-1,1,1-

trifluoroethane (HCFC-123) by P Shantan Rao, Y

Rambabu, S Narayan Reddy, M Sridhar, PVSS

Srinivas,T Yakaiah, BPV Ligaiah (India)

An improved process for the preparation of 2,2,2-

trifluoroethanol by B Narsaiah P Shantan Rao, S

Narayan Reddy, PVSS Srinivas (India)

Tiruchenduramine and derivatived b-carboline

derived guanidine alkaloids as a-glucosidase

inhibitors by Y Venkateshwarlu, K Ravinder, J S

Yadav, Y Sarath Kumar S Ramakrishna, P V Diwan, J

V Rao, P Ramesh, Hartmut Laatsch (India)

C2-fluoro pyrrolo[2,1-C] [1,4]benzodiazepine

dimers by Ahmed Kamal P S Murali Mohan Reddy,

D Rajasekhar Reddy (India)

C8-linked pyrrolo[2,1-C][1,4] benzodiazepine-

acridone/acridine hybrids by Ahmed

Kamal, O Srinivas, P Ramulu, G Ramesh Khanna, P

Praveen Kumar (India)

A process for the preparation of highly efficient

silver deposited on carbon covered alumina

catalyst in controlling microorganism in water by

K S Rama Rao, B David Raju, A H Padmasri, V

Sivakumar, A Naga Ratnakar, P Seetharamulu, V

Shashikala, B M Nagaraja, S Sreevardhan Reddy, P

N Sarma, K Krishna Prasad, S R Venkata Mohan

(India)

Therapeutic edible composition for treating

hyperglycemia by A S Chauhan, Ch Kishore Babu, S

Sridevi, Y Sharath Kumar, K Rajasekhar, G M Chary

(India)

Patents Filed in India and Overseas during

140

An improved process for the preparation ofpyridine and pyridine derivatives from ethanol.Patent No: 188716 Dt: 14/8/03

A process for the preparation of 5-oxy 1-1,3-dioxepanes. Patent No: 188717 Dt: 14/08/03

A process for preparation of novel N-hydroxy alkylcontaining cationic amphiphiles. Patent No:189751 Dt: 27/01/04

A process for the preparation of novaldipyranoquino-linones useful as anti-HIV agents.Patent No: 190036 Dt: 03/02/04

An improved process for the preparation of N-methylpiperazine. Patent No: 189382 Dt: 03/02/04

An improved process for the simultaneouspreparation of pyridine and picolines. Patent No:189373 (24/02/04

An improved process for the preparation ofcyanopyridines. Patent No: 190432 Dt: 24/02/04



A process for the preparation of crystalline,vanadium silico-aluminophosphate catalystsuseful for acid catalysed reactions. Patent No:190239 Dt: 12/03/04

An improved process for the preparation ofacetonitrile. Patent No: 190763 Dt: 15/3/04

An improved process for the preparation ofbenzonitrile. Patent No: 190760 Dt: 15/03/04



An improved process for the preparation ofcarbamates useful for agrochemicals, pharmaceuticals and peptide synthesis. Patent No: 190827Dt: 16/03/04

2004-052004-052004-052004-052004-05An improved process for the preparation ofacetonitrile from ethanol over vanadium aluminophospate catalyst. Patent No: 191169 Dt: 12/04/04

An improved process for the preparation ofacetonitrile. Patent No: 191083 Dt: 12/4/04

An improved process for the preparation ofamides. Patent No: 191100 Dt: 12/4/04

A new process for the preparation of aromatic nitrocompounds. Patent No: 191095 Dt: 12/4/04

An improved process of preparation of propanolamines as therapeutic agents. Patent No: 191210Dt: 26/04/04

An improved process for the enzymaticpreparation of optically pure glycidate esters.Patent No: 191208 Dt: 26/04/04

A process for the preparation of novel hydroxyalkyl containing cationic amphiphiles useful forintracellular delivery of biologically activemolecules. Patent No: 191266 Dt: 26/04/04

A process for the preparation of antimicrobialfraction from millingtonia hortensis. Patent No:191243 Dt: 26/4/04

An improved process for the preparation of 4,4’diaminobenzanilide (DABA). Patent No: 191481 Dt:30/06/04

A process for the synthesis of new heterocyclicsubstituted sulfamides useful as antibacterialagents. Patent No: 191416 Dt: 24/05/04

An improved process for acylation of naphthylethers. Patent No: 191514 Dt: 30/06/04

An improved process for preparation of ferrocenecapped olefins. Patent No: 191497 Dt: 30/06/04

An improved process for the preparation of 4b-substituted epipodopyllotoxins. Patent No:191366 Dt: 16/11/04

A process for the preparation of novel N-hydroxyalkyl containing cationic amphiphiles useful forintracellular delivery of biologically activemolecules. Patent No: 192393 Dt: 08/02/05

PATENTS GRANTED IN INDIAPATENTS GRANTED IN INDIAPATENTS GRANTED IN INDIAPATENTS GRANTED IN INDIAPATENTS GRANTED IN INDIA

2003-042003-042003-042003-042003-04

141

Process for synthesis of novel cationic amphiphiles

containing N-hydroxyalkyl group for intracellular

delivery of biologically active molecules. Patent No:

US 6541649 Dt: 1/4/03

Process for the preparation of supported osmates.

Patent No: US 6559291 Dt: 06/05/03

Process for the preparation of ethyl 2,3-dihydro

benzo [1,4] dioxin-2-carboxylate. Patent No:

6555695 Dt: 29/04/03

Process for the preparation of diazonaphtho

quinone sulfonyl-chlorides using diphosgene and

triphosgene. Patent No: US 6559291 Dt: 06/05/03

(+) – cycloolivil as antioxidant obtained from natural

source namely stereospermum personatum.

Patent No: US 6562381 Dt: 13/05/03

Process for the enhancement of the cycle life of a zinc-

chromium based catalyst in the synthesis of 2-

methylpyrazine. Patent No: US 6566292 Dt: 20/05/03

Process for preparation of 2-Methyl-1, 4-naphtho

quinone. Patent No: US 6579994 Dt: 17/06/03

Alkylxanthates and use of alkylxanthates in the

integrated pest management. Patent No: US

6583175 Dt: 24/06/03

Process for the preparation of a polyaniline salt.

Patent No: US 6586565 Dt: 01/07/03

(-)-Olivil as antioxidant which is obtained from a

new natural source namely stereospermum

personatum. Patent No: US 6592911 Dt: 15/07/03

Substituted calyx (4 pyrroles and process for the

synthesis of calyx (4 pyrroles over molecular sieve

catalysts. Patent No: US 6605194 Dt: 12/08/03

Process for the preparation of N-(2,3-Dihydrobenzo

[1,4] dioxin-2-carbonyl) piperazine. Patent No: US

6608200 Dt: 19/08/03

Preparation of alkylated aromatic amines. Patent

No: EP 1002789 Dt: 18/06/03

Process for the preparation of amine oxides. Patent

No: US 6617454 Dt: 09/09/03

Enzymatic process for preparing reduced-calorie

fats containing behenic acid. Patent No: US 6617141

Dt: 09/09/03

Process for the preparation of nitrotoluenes. Patent

No: US 6620981 Dt: 16/09/03

Process for the synthesis of highly active modified

carbon supported palladium catalyst. Patent No:

US 6624109 Dt: 23/09/03

Process for the preparation of polyaniline salt.

Patent No: US 6630567 Dt: 07/10/03

Process for simultaneous alkyl esterification of oil

and regeneration of spent oil purification medium.

Patent No: US 6635595 Dt: 21/10/03

Process for the preparation of hydroxylated lecithin

from crude soyabean lecithin. Patent No: US

6638544 Dt: 28/10/03

Supported osmates, process for preparation there

of, and a process for the preparation of chiral vicinal

diols using supported osmate catalyst. Patent No:

US 6646168 Dt: 11/11/03

Herbal chemical composition for the treatment of

cancer. Patent No: US 6649650 Dt: 18/11/03

PATENTS GRANTED OVERSEASPATENTS GRANTED OVERSEASPATENTS GRANTED OVERSEASPATENTS GRANTED OVERSEASPATENTS GRANTED OVERSEAS

2003-042003-042003-042003-042003-04

142


Method of processing of hydrogen for reductive

acylation of nitro, azido and cyano arenas. Patent

No: US 6649650 Dt: 06/01/04

Pyrimidine linked pyrrolo [2,1-C][1,4] benzodia

zepines as potential antitumour agents. Patent No:

US 6683073 Dt: 27/01/04

An improved process for the preparation of the acyl

napthyl ethers. Patent No: US 1149819 Dt: 16/04/03

A process for the preparation of acyl hetro aromatic

compounds from hetroaromatic compounds by

metal ion exchanged clays. Patent No: EP 1138681

Dt: 15/10/03

Process for the nitration of xylene isomers using

zeolites catalyst. Patent No: US 6703532 Dt: 09/

03/04

Process for the preparation of supported osmates.

Patent No: US 6703531 Dt: 09/03/04

Process for the preparation of rice bran oil low in

phosphorous content. Patent No: US 6706299

Dt: 16/03/04

Process for preparing taxol side chain using hetero

geneous trifunctional catalyst. Patent No: US

6706901 Dt: 16/03/04

Process for the separation of racemic mixtures.

Patent No: US 6709597 Dt: 23/03/04

Method for the synthesis and evaluation of

porphyrins, calix (4 pyrroles and allied macrocycles.

Patent No: US 6712972 Dt: 30/03/04

2004-052004-052004-052004-052004-05

Process for preparing substituted coumarins.

Patent No: US 6716996 Dt: 06/04/04

Process for the preparation of 2-chloro-5-

methylpyridine-3-carbaldehyde. Patent No: US

6737529 Dt: 18/05/04

1-(aryloxy) propionoyl-2-arylsulfonyl hydrazines,

process for preparation thereof and use thereof

as hypoglycemic agents. Patent No: US 6730704

Dt: 04/05/04

Process for the preparation of vinylpyridine from

picoline over modified zeolites Patent No: US

6727365 Dt: 27/04/04

Selective liquid phase air oxidation of toluene

catalysed by composite catalytic system. Patent

No: US 6743952 Dt: 01/06/04

Process for the transesterfication of keto ester with

alcohol using polyaniline salts as catalysts. Patent

No: US 6743942 Dt: 01/06/04

Process for the preparation of amine oxides. Patent

No: EP 6743952 Dt: 28/04/04

Process for the production of nitroarenes with high

para selectivity from monosubstituted aromatic

hydrocarbons using aluminosilicates as catalysts.

Patent No: EP 1004570 Dt: 06/05/04

A process for the preparation of 4’ -isobuty laceto

phenone by friedel crafts acylation of isobutyl

benzene. Patent No: EP 1138662 Dt: 30/06/04

Process for synthesis of bis-(substituted-4-quinolyl)

disulphides. Patent No: US 6777553 Dt: 17/0804

Multifunctional catalyst useful in the synthesis of

chiral vicinal diols and process for the preparation

of chiral vicinal diols using said multifunctional

catalysts. Patent No: US 6780810 Dt: 24/08/04

143

Process for the preparation of 2-nitrothiophene

selectively from thiophene using metal exchanged

clay catalyst. Patent No: US 6794521 Dt: 21/09/04

Process for the preparation of ZSM-5 catalyst.

Patent No: US 6800272 Dt: 05/1004

Pyrene-linked pyrrolo [2,1-c] [1,4] benzodiazepine

hybrids useful as anti-cancer agents. Patent No:

US 6800622 Dt: 05/10/04

Supported osmates, process for preparation

thereof, and a process for the preparation of chiral

vicinal diols using supported osmate catalyst.

Patent No: US 6815566 Dt: 09/11/04

Process for the preparation of nanocrystalline

zeolite beta. Patent No: US 6827924 Dt: 07/12/04

Process for the preparation of nanocrystalline

zeolite beta. Patent No: US 6827924 Dt: 07/12/04

Process for the preparation of b-keto aliphatic acid

ester. Patent No: US 6838083 Dt: 04/01/05

Process for the preparation of (-)-epicatechin from

a new natural source namely dichrostachys cinerea.

Patent No: US 6841687 Dt: 11/01/05

Composition for treating gastric ulcer and a process

for preparing the same. Patent No: US 6855347

Dt: 15/02/05

Process for the direct preparation of 5-alkoxy and

5-acyloxy analogues of camptothecins or

mappicene ketones. Patent No: US 6872829 (Dt:

29/03/05

Preparation of new layered double hydroxides

exchanged with osmate for asymmetric

dihyfroxylation of olefins to vicinoldiols Patent No:

EP 1209142 Dt: 26/03/05

An improved process for the preparation of

acylaromatic ethers Patent No: JP 532824 Dt: 31/

05/04 EP 1149818 Dt: 29/12/04

An improved process for the preparation of tetra

bromobisphenol-A. Patent No: JP 3532825 Dt: 31/5/04

A novel chromatographic finger printing of herbal

medicines and formulations. Patent No: EA 004663

(24/6/04

Process for the preparation of acylferrocenes. Patent No:

JP 3574805 Dt: 9/7/04Patent No: EP 1268501 Dt: 21/7/04

Patent No: CN 116674C (15/9/04

Process for the preparation of Malononitrile. Patent

No: EP 1184369 (11/8/04

A process for the preparation of 1,1,12-tetra fluoroe

thane. Patent No: GB 2375974 Dt: 11/8/04

A new antioxidant from natural source. Patent No:

US 6781002 Dt: 24/8/04

Process for the preparation of polyaniline salt.

Patent No: AU 002242943 Dt: 26/8/04

An ecofriendly process for the preparation of

dinitramidic acid and salts by metal ion exchanged

clay catalysts. Patent No: US 6787119 Dt: 7/9/04

Patent No: EP 1344748 Dt: 15/12/04

A process for the alkylation of dihydroxy benzene

with tertiary butyl alcohol using solid acid and

polyaniline sulfide catalysts. Patent No: GB

2378441 Dt: 22/9/04 Patent No: FR 2822822 Dt:

24/9/04

Process for the preparation of amine oxides Patent

No: EP 1213280 Dt: 29/9/04

Alkylxanthates and use of alkylxanthates in the

integrated pest management. Patent No: EP

1373238 Dt: 3/11/04

Stereoselective preparation of 3-hydroxy-3-phenyl

propionitrile. Patent No: GB 2387597 Dt: 10/11/

04

Vitamin B12-biodegradable micro particulate

conjugate carrier systems for peroral delivery of

drugs, therapeutic peptides / proteins and vaccines.

Patent No: GB 2374010 Dt: 29/12/04

Patents Granted Overseas During

144

ARAVINDAN, PG;SELVANAYAGAM, S;YOGAVEL, M; VEL

MURUGAN, D; RAVIKUMAR, K;NAGARAJAN, N;PERUMAL,

PT, 3-chloro-3-(9-ethyl-6-methyl-9H-carbazol-3-yl)

propenalActa Crystallo graphica

Section E(Structure Reports Online) (2003) 59(9) :

O1432-O1434

ARAVINDAN, PG;SELVANAYAGAM, S;VELMURUGAN,

D;RAVIKUMAR, K; NAGARAJAN, R;PERUMAL, PT, C-

Halogen center dot center dot center dot pi interacti

ons in 4-chloro-2-(9-ethylcarbazol-3-yl)quinoline-1(2H)-

carbaldehyde

Acta Crystallo graphica, Section E (Structure Reports

Online) (2003) 59(10):O1564-O1566

BABU, KS;SRINIVAS, PV;PRAVEEN, B;KISHORE, KH;MURTY,

US;RAO, JM, Antimicrobial constituents from the

rhizomes of Rheum emodi

Phytochemistry (2003) 62(2) : 203-207

BABU, KS;RAJU, BC;PRAVEEN, B;KISHORE, KH;MURTY,

US;RAO, JM, Microwave assisted synthesis and

antimicrobial activity of 2,2-dimethylchromenes

Heterocyclic Communications (2003) (9) : 519-526

BABU, KS;RAJU, BC;SRINIVAS, PV;RAO, JM, Highly efficient

and chemoselective cleavage of prenyl ethers using

ZrCl4/NaBH

4

Tetrahedron Letters (2003) 44(12) : 2525-2528

BABU, KS;RAJU, BC;SRINIVAS, PV;SRIDHAR, A;KUMAR, SP;

RAO, JM, A simple, efficient and highly selective cleavage

of 3-methylbut-2-enyl(prenyl)ethers using p-

toluenesulfonic acid

Chemistry Letters (2003) 32(8) : 704-705

BANERJEE, RAJKUMAR; KUMAR DAS, PRASANTA;

SRILAKSHMI, GOLLAPUDI VENKATA; RAO, NM;

CHAUDHURI, A, Novel Cationic Transfection Lipids For

Use In Liposomal Gene Delivery

Surfactant Science Series (Adsorption And Aggregation Of

Surfactants In Solution) (2003) 109 : 603-617

20032003200320032003ALAM, MM, (S)-(-)-1-amino-2-methoxypyrrolidine (SAMP)

and (R)-(+)-1-amino-2-methoxypyrrolidine (RAMP) as

versatile chiral auxiliaries

Synlett (2003) (11) : 1755-1756

ALAM, MM, (S)-(-)-1-Amino-2-methoxymethylpyrrolidine

(Samp) and (R )-(+)-1-Amino-2 methoxyme

thylpyrrolidine (Ramp) as Versatile chiral auxilliaries

(Sept, Pg. 1755, 2003)

Synlett (2003) (13) : 2099-2100

ALAM, MM;VARALA, R;ADAPA, SRINIVAS R, Conjugate

addition of indoles and thiols with electron-deficient

olefins catalyzed By Bi(OTf )3 -


ALAM, MM;ADAPA, SRINIVAS R, A facile synthesis of

phenylacetic acids via Willgerodt-Kindler reaction under

PTC Condition -

Synthetic Communications (2003) 33(1) : 59-63

ALAM, MM;VARALA, R;ADAPA, SRINAVAS R, Bi(Otf )3-

catalyzed Baeyer-Villiger oxidation of carbonyl

compounds with m-CPBA -


ANAND, P;SRIDHAR, J;VENKATESWARLU, Ch, Heat release

estimator based globally linearizing control of a

chemical reactor

Indian Journal of Chemical Technology (2003) 10 : 539-544

ANNAPURNA, JETTY;AMARNATH, PVS;KUMAR, DA; RAMA

KRISHNA, SV; RAGHAVAN, KV, Antimicrobial activity of

Ixora coccinea leaves

Fitoterapia (2003) 74(3) : 291-293

ANU, SJ;RAO, JM, New norfriedelene-1,3-dione from the

root bark of Salacia oblonga, Indian Journal of Chemistry

Section B-Organic Chemistry Including Medicinal

Chemistry (2003) 42(5) : 1180-1182

PUBLICATIONSPUBLICATIONSPUBLICATIONSPUBLICATIONSPUBLICATIONS

145

BASAK, P;NISHA, CK;MANORAMA, SV;MAITI, S;JAYA

CHANDRAN, KN, Probing the association behavior of

poly(ethylene glycol)-based amphiphilic Comb-like

polymer in NaCl solution

Journal of Colloid and Interface Science (2003) 262(2):

560-565

BHASKAR, G;RAO, BV, Stereoselective synthesis of L-

733,060


BHASKARAN, S;SELVANAYAGAM, S;VELMURUGAN, D;

RAVIKUMAR, K; ANNIYAPPAN, M;MURALIDHARAN,

D;PERUMAL, PT, N-(4a-morpholino-2,3,4,4a,9,9a-

hexahydro-1H-xanthen-9-yl)phenylamine

Acta Crystallographica , Section E(Structure Reports

Online) (2003) 59(9) : O1301-O1303

BHASKARAN, S;SELVANAYAGAM, S;RAJAKANNAN,

V;VELMURUGAN, D;RAVIKUMAR, K;RASHEED,

AMA;RAJAKUMAR, P, 34,35-dimethyl-13,20-dioxa-10,23-

diaza-3,30 dithiapentacyclo[30.4.0.0(4,9).0(14,19).0

(24,29)] hexatriconta -(36),4,6,8,14,16,18,24,26,28,32,34-

dodecane-11,22-dione

Acta Crystallographica , Section E(Structure Reports

Online) (2003) 59(9) : O1304-O1306

BHASKARAN, S;SELVANAYAGAM, S;RAJAKANNAN,

V;VELMURUGAN, D;RAVIKUMAR, K;RASHEED, AMA; RAJA

KUMAR, P, 30,31-dimethyl-3,26-dioxa-11,18- diazapenta

cyclo [26.4.0.0(4,9).0(12,17).0(20,25)] dotriconta-1(32),

4,6,8, 12,14,16,20,22,24,28,30- dodecane-10,19-dione -

Acta Crystallographica, Section E(Structure Reports

Online) (2003) 59(9) : O1429-O1431

BHATTACHARYA, RAJARSHI;PHANIRAJ, TN;SHAILAJA, D,

Polysulfone and polyvinyl pyrrolidone blend membra

nes with reverse phase morphology as controlled

release systems: experimental and theoretical studies

Journal of Membrane Science (2003) 227(1-2) : 23-37

BORUAH, A;RAO,IN;NANDY, JP;KUMAR, SK;KUNWAR,

AC;IQBAL, J, Synthesis of a novel cis-proline-derived

cyclic type VI beta-turn mimic via Ring-closing

metathesis

Journal of Organic Chemistry (2003) 68(12) : 5006-

5008

BOSE, DS;FATIMA, L;MEREYALA, HB, Green Chemistry

approaches to the synthesis of 5-Alkoxycarbonyl-4-aryl-

3,4-Dihydropyrimidin-2(1H)-ones by a Three-Compo

nent Coupling of One-Pot condensationreaction:

Comparison of Ethanol, water and solvent free

conditions

Journal of Organic Chemistry (2003) 68(2) : 587-590

BOSE, DS;KUMAR, KK;REDDY, AV, NARSIMHA, A new

protocol for selective deprotection of N-tert-

butoxycarbonyl protective Group (t-boc) with Sn(OTf )(2)


BOSE, DS;REDDY, AV NARSIMHA, Iodine(V) reagents in

organic synthesis. Dess–Martin periodinane mediated

Efficient one-pot oxidation of aldehydes to acyl azides


BOSE, DS;REDDY, AV NARSIMHA;DAS, APR, Simple,

economical and environmentally benign selective

regeneration of carbonyl compounds from oximes and

N,N-dimethyl hydrazones

Synthesis-Stuttgart (2003) (12):1883-1885

CHAKRABORTY, TK, Grow a head from within

Current Science (2003) 84(1) : 7

CHARKABORTY, TK;GHOSH, A;KUMAR, SK;KUNWAR, AC,

Nucleation of beta-Hairpin structures with Cis Amide

Bonds in E-Vinylogous Proline-containing Peptides


CHAKRABORTY, TK;GHOSH, A;RAJU, TV, Efficient ring

opening reactions of N-tosyl aziridines with amines and

water in presence of catalytic amount of cerium(IV)

ammonium nitrate


Publications

146


CHANDRA SEKHAR, K;CHARY, NS;TIRUMALA,

KC;APARNA, V, Determination of trace metals in sea

water by ICP-MS after matrix separation

Acta Chimica Slovenica (2003) 50(3) : 409-418

CHANDRA SEKHAR, K;KAMALA, CT;CHARY, NS;

ANJANEYULU, Y, Removal of heavy metals using a plant

biomass with reference to environmental control

International Journal of Mineral Processing (2003)

68(1-4) : 37-45

CHANDRA SEKHAR, K;CHARY, NS;KAMALA,

CT; ANUPAMA, M, Role of certified reference materials in

chemical speciation studies

MAPAN Metrology Society of India (2003) 18 : 25-35

CHANDRA SEKHAR, S;BABU, BN;REDDY, CHR, Single-step

conversion of N-benzyl, N-trityl and N-diphenylmethyl

amines to t-butyl carbamates using polymethyl

hydrosiloxane


CHANDRA SHEKAR, S;MURTHY, JK;RAO, PK;RAO, KSR, Pd

supported on fluorinated carbon covered alumina

(FCCA) a high performance Catalyst in the

hydrodechlorination of dichlorodifluoromethane

Catalysis Communications (2003) 4(2) : 39-44

CHANDRA SHEKAR, S;MURTHY, JK;RAO, PK;RAO, KSR, Selective

hydrogenolysis of dichlorodifluoromethane on carbon covered

alumina Supported palladium catalyst

Journal of Molecular Catalysis A: Chemical (2003)

191(1) : 45-59

CHANDRA SHEKAR, S; NARASIHMULU, CH; JAGADESHWAR, V;

REDDY, KV ; The first Corey–Chaykovsky epoxidation and

cyclopropanation in ionic liquids


CHANDRA SHEKAR, S;NARSIHMULU, CH;REDDY,

NR;REDDY, MS, Triethylborane triggered intermolecular

domino Michael-aldol three-component Coupling

reactions


CHAKRABORTY, TK;MOHAN, BK;KUMAR, SK;KUNWAR, AC,

Nucleation of beta-hairpin structure in a pyrrole amino

acid containing peptide


CHAKRABORTY, TK;LAXMAN, P, Total synthesis of (+)-

crocacin A


CHAKRABORTY, TK;PURKAIT SUBHAS;DAS, S, Synthesis

of chiral 4-hydroxy-2,3-unsaturated carbonyl

compounds from 3,4-epoxy alchols by oxidation :

Application in the formal synthesis of macrosphelide-A

Tetrahedron (2003)59(46):9127-9135

CHAKRABORTY, TK;TAPADAR, S, Synthesis of (+)-prelactone B


CHAKRABORTY, TK;REDDY, V RAMAKRISHNA;REDDY, T

JAGADESHWAR, Synthesis of highly substituted

tetrahydropyrans: preparation of the C20-C28 Moiety

of phorboxazoles

Tetrahedron (2003) 59(43) : 8613-8622

CHAKRABORTY, TK;SRINIVASU, P;BIKSHAPATHY,

E;NAGARAJ, R; VAIRAMANI, M;KUMAR, SK;KUNWAR, AC

Cyclic homooligomers of furanoid sugar amino acids


6263

CHANDRA SEKHAR, G;RAO, MVP;PRASAD, DHL;KUMAR,

YVLR, Excess molar enthalpies of N,N-dimethy

lacetamide with substituted benzenes at 298.15 K

Thermochimica Acta (2003) 402(1-2) : 99-103

CHANDRA SEKHAR, K;CHARY, NS;KAMALA, CT;RAO,

J VENKATESWARA; BALARAM, V;ANJANEYULU, Y, Risk

assessment and pathway study of arsenic in industrially

contaminated sites of Hyderabad: a case study

Environment International (2003) 29(5) : 601-611

147

CHANDRA SHEKAR, S;MURTHY, JK;RAO, PK;RAO,

KSR;KEMNITZ, E, Selective hydrogenolysis of

dichlorodifluoromethane (CCl2F

2) over CCA supported

palladium bimetallic catalysts

Applied Catalysis A: General (2003) 224(1) : 39-48

CHANDRA SHEKAR, S;NARSIHMULU, C;SULTANA,

SS;SARITHA, B; PRAKASH, SJ, Solvent and catalyst free

three-component coupling of carbonyl compounds,

Amines and triethylphosphite; a new synthesis of alpha-

aminophosphonates

Synlett (2003) (4) : 505-506

CHANDRA SHEKAR, S;NARSIHMULU, C;SULTANA,

SS;REDDY, NR, Osmium tetroxide in poly(ethylene glycol)

(PEG): a recyclable reaction medium for rapid

asymmetric dihydroxylation under sharpless conditions

Chemical Communications (2003) (14) : 1716-1717

CHANDRA SHEKAR, S;SRINIVAS, C;SRIHARI, P, Phenyl

sulphonyl acetaldehyde diethyl acetal: A new robust

1,2-diol protective group - Synthetic Communications

(2003) 33(6) : 895-902

CHARY,KVR; RAMESH,K; VIDYASAGAR, G;RAO,VV, Vapour

phase alkylation of phenol with methanol over

vanadium oxide supported on zirconia


188(1-2) : 195-204

CHARY, KVR;KISHAN, G;KUMAR, CP;VIDYASAGAR, G;

NIEMATSVERDRIET, JW - Characterization and reactivity

of vanadiuim oxide catalysts supported on niobia


CHARY,KVR; KISHAN,G; KUMAR,CP; VIDYASAGAR,G,

Structure and catalytic properties of vanadium oxide

supported on alumina


CHARY, KVR;KISHAN, G;RAMESH, K;KUMAR, CP; VIDYA

SAGAR, G, Synthesis, characterization and catalytic

properties of Vanadium oxide catalysts supported on

AlPO4

Langmuir (2003) 19(11) : 4548-4554

CHARY, KVR; LAKSHMI, KS;MURTHY, MRVS;RAO,

KSR;PAPADAKI, MARIA, Hydrodechlorination of 1,2-4-

trichlorobenzene over niobia supported nickel catalysts


CHAUHAN, AS;SRIDEVI, S;CHALASANI, KB;JAIN, AK;JAIN,

SK; JAIN, NK;DIWAN, PV Dendrimer-mediated

transdermal delivery: enhanced bioavailability of

indomethacin

Journal of Controlled Release (2003) 90(3) : 335-343

CHAUDHURI, A, Cationic Transfection Lipids-Preface

Current Medicinal Chemistry (2003) 10(14) : U2-U2

CHOUDARY, BM;MULUKUTLA, RS;KLABUNDE, KJ,

Benzylation of aromatic compounds with different

crystallites of MgO

Journal of the American Chemical Society (2003)

125(8) : 2020-2021

CHOUDARY, BM;JYOTHI, K;MADHI, S;KANTAM, ML,

Catalytic asymmetric dihydroxylation of aliphatic

olefins with reusable Resin-osmium tetroxide

Advanced Synthesis & Catalysis (2003) 345(11) : 1190-

1192

CHOUDARY, BM;KANTAM, ML;REDDY, CRV;BHARATHI,

B;FIGUERAS, F, Wadsworth–Emmons reaction: the

unique catalytic reaction by a solid base

Journal of Catalysis (2003) 218(1) : 191-200

CHOUDARY, BM;REDDY, CRV;PRAKASH, BV;KANTAM,

ML;SREEDHAR, B, The first example of direct oxidation

of sulfides to sulfones by an osmate Molecular oxygen

system


CHOUDARY, BM;KANTAM, ML;RAHMAN, A;REDDY,

VENKAT CHINTA, Selective reduction of aldehydes to

alcohols by calcined Ni-Al hydrotalcite

Journal of Molecular Catalysis-A : Chemical (2003)

206(1-2) : 145-151

Publications

148


DEVI, P SITA; TLC as a tool for quantitative isolation of

conjugate trienoic FA

Journal of American Oil Chemists Society (2003) 80(4)

: 315-318

DEVI, SS;MALATHI, R;RAJAN, SS;ARAVIND, S;KRISHNA

KUMARI, GN; RAVIKUMAR, K; A new clerodane diterpene

with antifeedant activity from Teucrium tomentosum,

Acta Crystallographica - Section C

Crystal Structure Communications (2003) 59(9) :

O530-O532

DHEVI, DM;PRIYAKUMAR, UD;SASTRY, GN; Silaaromaticity

in polycyclic systems: A computational study


1171

DINADAYALANE, TC;GEETHA, K;SASTRY, GN; Ab initio and

density functional theory (DFT ) study on [1,5]

sigmatropic, Rearrangements in pyrroles, phospholes,

and siloles and their Diels-Alder reactivities,

Journal of Physical Chemistry- A (2003) 107(28) :

5479-5487

DINADAYALANE, TC;DEEPA, S;SASTRY, GN; Is peri

hydrogen repulsion responsible for flattening bucky

bowls? The effect of Ring annelation to the rim of coran

nulene,

Tetrahedron Letters (2003) 44 (24) : 4527-4529

DINADAYALANE, TC; PUNNAGAI, M;SASTRY, GN; A

theoretical study on cycloaddition reactions between

[c]-annelated heterocyclic Five-membered dienes and

acetylene,

Journal of Molecular Structure: THEOCHEM (2003)

626(1-3) : 247-262

DINADAYALANE, TC;SASTRY, GN; Isolated pentagon rule

in buckybowls: a computational study on thermody

namic stabilities and bowl-to bowl inversion barriers

Tetrahedron (2003) 59(42) : 8347-8351

CHOUDARY, BM;SOMESHWAR,T;REDDY, ChV;KANTAM, M

LAKSHMI; RATNAM, JEEVA, K;SIVAJI, LV, The first example

of bromination of aromatic compounds with unprece

dented atom Economy using molecular bromine


CHOUDARY,BM;CHOWDARI,NS;JYOTHI, K;KANTAM, ML,

Heterogeneous catalytic asymmetric aminohy

droxylation of olefins using LDH-Supported OsO4

Journal of Molecular Catalysis A: Chemical (2003)196(1-2) : 151-156

CHOUDARY, BM;CHOWDARI, NS;MADHI, S;KANTAM ,ML,

A trifunctional catalyst for one-pot synthesis of chiral

diols via Heck coupling-N-Oxidation-asymmetric

dihydroxylation: application for the synthesis of

diltiazem And taxol side chain


DANADEVI,K; ROZATI,R; BANU,BS; RAO,PH;GROVER,P,

DNA damage in workers exposed to lead using comet

assay

Toxicology (2003) 187(2-3) : 183-193

DANADEVI, K;ROZATI, R;REDDY, PP;GROVER, P, Semen

quality of Indian welders occupationally exposed to

nickel and chromium

Reproductive Toxicology (2003) 17(4) : 451-456

DAS, B;BANERJEE, J;RAMU, R;PAL, R;RAVINDRANATH,

N;RAMESH, C; Efficient, selective deprotection of

aromatic acetates catalyzed by Amberlyst-15 or iodine


DAS, B;KASHINATHAM, A;VENKATAIAH, B;SRINIVAS, KVNS;

MAHENDER, G;REDDY, MR Cleomiscosin A, a coumarino-

lignoid from Jatropha gossypifolia

Biochemical Systematics and Ecology (2003) 31(10) :

1189-1191

DEVI, BLAP;KARUNA, MSL;RAO, KN;SAIPRASAD,

PS;PRASAD, RBN; Microwave-assisted catalytic transfer

hydrogenation of safflower oil

Journal of the American Oil Chemists Society (2003)

80(10) : 1003-1005

149

DINADAYALENE, TC; SASTRY, GN; Density functional

theory study on dimerizations of phospholes,Organometallics (2003) 22(26) : 5526-5533

DURGAKUMARI, V;SAROJA, G;RATNAMAL,A;SUBRAHMANYAM; Vapour phase acylation of phenolover HB, CeHB and SO

42-/ZrO

2

Reaction Kinetics & Catalysis Letters (2003) 79 : 43-51

ETTI, S; SHANMUGAM, G;PONNUSWAMY, MN;SRIDHAR,R;MURUGAN, R; PERUMAL, PT;RAVIKUMAR, K; Ethyl 3-methyl-1-(2,4-dinitrophenyl)-1H-pyrazole-4-carboxylateActa Crystallographica , Section E (Structure ReportsOnline) (2003) 59(Part 11) : O1835-O1837

FADNAVIS, NW;BHASKAR, V;KANTAM, ML;CHOUDARY,BM; Highly efficient “Tight Fit” Immobilization of alpha-Chymotrypsin in Mesoporous, MCM-41: A novelapproach using Precursor immobilization andactivationBiotechnology Progress (2003) 19(2) : 346-351

FADNAVIS, NW;SHEELU, G;KUMAR, BM;BHALERAO,MU;DESHPANDE, AA; Gelatin blends with alginate: gelsforlipase immobilization and purificationBiotechnology Progress (2003) 19(2) : 557-564

GADI, R;KULSHRESTHA, UC;SARKAR, AK;GARG,SC;PARASHAR, DC; Emissions of SO2 and NOx frombiofuels in India Tellus Series BChemical & Physical Meteorology (2003) 55(3) : 787-795

GEETHA, K;DINADAYALANE, TC;SASTRY GN; Effect ofmethyl and vinyl substitution on the geometries,relative stabilities and Diels-Alder reactivities ofphospholes: a DFT studyJournal of Physical Organic Chemistry (2003) 16(5) :298-305

GEORGE, JOHN;SASTRY, NV;PRASAD, DHL; Excess molarenthalpies and excess molar volumes of methyl methacrylate, +benzene+Toluene+P-xylene,+ cyclohexaneand + aliphatic diethers (diethyl, diisopropyl anddibuthyl)

Fluid Phase Equlibria (2003) 214(1) : 39-51

GNANAKUMARI, P;RAO, MVP;PRASAD, DHL;KUMAR,

YVLR; Vapor-liquid equilibria and excess molar

enthalpies for N-methyl-2-pyrrolidone with

chloroethanes and chloroethenes

Journal of Chemical and Engineering Data (2003)

48(3), 535-540

GOPINATH, N RAJESH;LINGAIAH, B;SREEDHAR,

B;SURYANARAYANA, I; PRASAD, PS SAI;OBUCHI, AKIRA;

Highly stable Pd/CeO2 catalyst for hydrodechlorination

of chlorobenzene

Applied Catalysis B: Environmental (2003) 46(3) :

587-594

GOPINATH,R;LINGAIAH, N;SURYANARAYANA, I;PRASAD,

PSS; Studies on microwave irradiated Pd/Nb2O5

catalysts: Effect of palladium chloride precursor on the

chlorobenzene hydrodechlorination activity

Reaction Kinetics & Catalysis Letters (2003) 79(1) : 61-67

GOUD, T VENKATESWAR;SRINIVASULU, M;REDDY, VLNR;

REDDY, ADELLI V;RAO, TP;KUMAR, DS;MURTY, U

SURYANARAYANA;VENKATESWARLU, Y; Two new

Bromotyrosine derived metabolites from the Sponge

Psammaplysila Purpurea

Chemical and Pharmaceutical Bulletin (2003) 51(8) :

990-993

GOUD, T VENKATESWAR; REDDY, N SRINIVASA;SWAMY,

NR;TEJOMOORTULA, SIVA RAM; VENKATESWARLU, Y;

Anti-HIV active petrosins from the marine sponge

Petrosia similis

Biological and Pharmaceutical Bulletin (2003) 26(10)

: 1498-1501

GOVIND, MM;SELVANAYAGAM, S;VELMURUGAN,

D;RAVIKUMAR, K;SRIDHAR, G;RAGHUNATHAN, R; 4 ‘-(p-

Methoxyphenyl)-1 ‘-methyl-1H-indole-3-spiro-2 ‘-

pyrrolidine- ‘-spiro-1 ‘’-cyclopentane-2(3H),2 ‘’ dione

Acta Crystallographica , Section E (Structure Reports

Online) (2003) 59(Part 10):O1438-O1440

Publications

150


JAYANTY, S;PRASAD, GK;SREEDHAR, B;RADHAKRISHNAN,

TP; Polyelectrolyte templated polyaniline-film

morphology and conductivity

Polymer (2003) 44(24) : 7265-7270

KAMAL, A;CHOUHAN, G; Chemoselective thioacetali

zation and transthioacetalization of carbonyl

compounds catalyzed by immobilized scandium(III)

triflate in ionic liquids,


KAMAL, A;KHANNA, GBR;RAMU, R;KRISHNAJI, T; Chemo

enzymatic synthesis of duloxetine and its enantiomer:

lipase-catalyzed Resolution of 3-hydroxy-3-(2-thienyl)

propanenitrile


KAMAL, A;KUMAR , B ASHWINI;ARIFUDDIN, M; A one-pot,

efficient and facile synthesis of 4b-arylaminopodophy

llotoxins: Synthesis of NPF and GL-331 as DNA

topoisomerase II inhibitors


KAMAL, A;RAMANA, K VENKATA;RAMANA, A VENKATA;

HARI BABU, A; Chemoenzymatic enantio selective

synthesis of 3-hydroxy-2-pyrrolidinones And 3-

Hydroxy-2-piperdinones

Tetrahedron: Asymmetry (2003) 14(17) : 2587-2594

KAMAL, A;RAMESH, G;RAMULU, P;SRINIVAS, O;REHANA,

TASNEEM; SHEELA, G; Design and synthesis of novel

chrysene-linked pyrrolo[2,1-c] [1,4]-benzodiazepine

Hybrids as potential DNA-binding agents

Bioorganic and Medicinal Chemistry Letters (2003)

13(20) : 3451-3454

KAMAL, A;RAMULU, P;SRINIVAS, O;RAMESH, G; Synthesis

of C-8 methanesulphonate substituted pyrroloben

zodiazepines as Potential antitumour agents

Bio organic and Medicinal Chemistry Letters (2003)

13(20) : 3517-3519


D;RAVIKUMAR, K; SRIDHAR, ;RAGHUNATHAN, R; 1N-

Methyl-spiro[2-3 ‘]indan-1,3-dione-spiro[3-3 ‘’]-5 ‘’-benzy

lidene-N-methyl-piperidinone-4-phenylpyrr olidine


Online) (2003) 59 (Part 11):O1680-O1681


D;RAVIKUMAR, K;DURGA, RR;RAGHUNATHAN, R; 1,2,3,4-

Tetrahydro-4 ‘-furfuryl-1 ‘-methylnaphthalene-2-spiro-

3-pyrrolidine-2 ‘-spiro-1 ‘’-acenaphthene-1,2 ‘’-dione


Online) (2003) 59(Part 12):O1875-O1877


D;RAVIKUMAR, K; SRIDHAR, G;RAGHUNATHAN, R; 5 ‘’-

Benzylidene-1 ‘-methyl-4 ‘-phenylindole-3-spiro-2 ‘-

pyrrolidine-3’-spiro-3 ‘’-piperidine-2(3H),4 ‘’-dione


Online) (2003) 59(Part 12):O1878-O1880

GROVER, P;DANADEVI, K;MAHBOOB, M;ROZATI, R;BANU, BS;

RAHMAN, MF; Evaluation of genetic damage in workers

employed in pesticide production Utilizing the Comet

Assay Mutagenesis (2003) 18(2) : 201-205

HEYDORN, LN;WONG, CY;SRINIVAS, R;TERLOUW, JK; The

isobaric ions CH3O—P=O.+ and CH

3O—P—NH

2+ and their

neutral Counterparts: a tandem mass spectrometry and

CBS-QB3 computational study

International Journal of Mass Spectrometry (2003)

225(1) : 11-23

JAYACHITRA, G;YASMEEN, N;RAO, KS;RALTE,

SL;SRINIVASAN, R; SINGH, AK; Borontrifluoride etherate

promoted one-pot conversion of nitriles to esters


JAYALAKSHMI, M;RAO, MM;SCHOLZ, F; Electrochemical

behavior of solid lithium manganate (LiMn2O4) in

aqueous neutral electrolyte solutions

Langmuir (2003) 19(20) : 8403-8408

151

KAMAL, A;RAMULU, P;SRINIVAS, O;RAMESH, G; Synthesis

and DNA-binding affinity of A-C8/C-C2 alkaxyamido-

linked pyrrolo [2,1-C][1,4] benzodiazepine dimers

Bioorganic & Medicinal Chemistry Letters (2003)13(22) : 3955-3958

KAMAL, A;REDDY, PSMM;REDDY, DR; An efficient catalytic

deprotection of thioacetals employing bismuth triflate:

Synthesis of pyrrolo[2,1-c] [1,4] benzodiazepines


KAMAL, A;REDDY, L;DEVAIAH, V;REDDY, GSK; Facile

reduction of aromatic nitro/azido functionality on solid

support employing Al/NiCl2·6H2O and Al/NH4Cl:

synthesis of pyrrolo[2,1-c][1,4]benzodiazepines


KAMAL, A;SANDBHOR, M;SHAIK, AA; Application of a

one-pot lipase resolution strategy for the synthesis of

chiral – And –lactones


KAMAL, A;SANDBHOR, M;SHAIK, ALI AHMED;SRAVANTHI,

V; One-pot synthesis and resolution of chiral allylic

alcohols

Tetrahedron Asymmetry (2003) 14(18) : 2839-2844

KAMAL, A;SANDBHOR, M;AHMED, KALEEM;ADIL,

SF;SHAIK, AHMAD ALI; Chemoenzymatic synthesis of

enantiomerically pure terminal 1,2-diols


KAMAL, A;SRINIVAS, O;RAMULU, P;RAMESH, G;KUMAR,

P PRAVEEN; Synthesis of novel C2 and C2 – C8

linked pyrrolo[2,1-c][1,4] Benzodiazepine-

Naphthalimide hybrids as DNA-binding agents


13(20) : 3577-3581

KAMAL, A;ASHWINI KUMAR, B; ARIFUDDIN, M; DASTIDAR,

SUNANDA G; Synthesis of 4beta-amido and 4beta-

sulphonamido analogues of podophyllotoxin as

potential antitumour agents

Bioorganic and Medicinal Chemistry (2003) 11(23) :

5135-5142

KANTAM, M LAKSHMI;HARITHA, Y;REDDY, NM;

CHOUDARY, BM; FIGUERAS, F; Clarification for the

comments on our article “Cyclopropanation of olefins

Using a silica gel anchored palladium phosphine

complex” Catal. Lett, 83, 187, 2002 by Jose M. Fraile, Jose

I. Garcia, and Jose A. Mayoral, “Cyclopropanation of

olefins with heterogeneous catalysts”

Catal. Lett, 88, 31, 2003 Catalysis Letters (2003) 90(3-4) : 231

KANTHAM, M LAKSHMI;JAYALAKSHMI, KAK;LIKHAR, PR;

Bis(Cyclopentadienyl) zirconium dichloride, an efficient

catalyst for highly selective Formation of beta-alkoxy

alcohols via ring opening of 1,2-epoxides with alcohols

Catalysis Letters (2003) 89(1-2) : 95-97

KANTHAM, M LAKSHMI;KAVITHA, B;NEERAJA, V;HARITHA,

Y; CHAUDHURI, MK; DEHURY, SK;Microencapsulatd

Cu(acac)2: a recoverable and reusable polymer-

supported copper catalyst for aziridination of olefins


KARLE, I; GILARDI, RD;RAO, CC; MURALEEDHARAN,

KM;RANGANATHAN, S; Unique assemblies of alternating

positively and negatively charged layers, directed by

hydrogen bonds, ionic interactions, and pi-stacking in

the crystal structures of complexes between mellitic

acid (benzenehexacarboxylic acid) and five planar

aromatic bases

Journal of Chemical Crystallography (2003) 22 (10) :

727-749

KARLE, I;RANGANATHAN, D; Construction of polar and

hydrophobic pores and channels by assembly of Peptide

molecules

Journal of Molecular Structure (2003) 647(1-3) : 85-96

KAZINCZY, B;KOTAI, L;GACS, I;SAJO, IE;SREEDHAR,

B;LAZAR, K; Study of the preparation of zinc(II) ferrite

and ZnO from zinc- and iron-containing Industrial

wastes

Industrial and Engineering Chemistry Research (2003)

42(2) : 318-322

Publications

152


KULSHRESTHA, MJ;KULSHRESTHA, UC;PARASHAR,

DC;VAIRAMANI, M; Estimation of SO4 contribution by

dry deposition of SO2 onto the dust Particles in India

Atmospheric Environment (2003) 37(22) : 3057-3063

KUMAR, AR;BHASKAR, G;MADHAN, A;RAO, BV;

Stereoselective synthesis of (-)-cytoxazone and (+) 5-

epi-cytoxazone


KUMAR, AR;RAO, BV; An efficient synthesis of protected

(2R,3R,4S)-4,7-diamins-2,3-dihydroxyheptanoic Acid, A

constituent of callipeltins A&D


KUMAR, AR;REDDY, JS;RAO, BV; A short, simple and

general approach for the synthesis of (3S,4S)-3-

methoxy-4-methylamino Pyrrolidone


KUMAR, AS;HARITHA, B;RAO, BV; A versatile and efficient

synthesis of (2S)-2-(hydroxymethyl)-N-Boc-2,3-Dihydro-

4-pyridone


KUMAR, HMS;RAO, MS;JOYASAWAL, S;YADAV, JS;

Condensation of orthoacetates with aldehydes: a new

strategy for the Preparation of ,-unsaturated esters


KUMAR, VV;SINGH, RS;CHAUDHURI, A; Cationic

Transfection Lipids in Gene Therapy: Successes, Set-

backs, Challenges and Promises

Current Medicinal Chemistry (2003) 10(14) : 1297-1306

KUMAR, VV;PICHON, C;REFREGIERS, M;GUERIN,

B;MIDOUX, P; CHAUDHURI, A; Single Histidine

functionality is sufficient to impart remarkable gene

transfection properties to Cationic Lipids: Evidence for

membrane fusion at acidic pH

Gene Therapy (2003) 10(15) : 1206-1215

KIRUMAKKI, SR; NAGARAJU, N;CHARY, KVR;NARAYANAN,

S Kinetics of esterification of aromat0ic carboxylic acids

over zeolites H and HZSM5 using dimethyl carbonate

Applied Catalysis A: General (2003) 248(1-2) : 161-

167

KISHORE, PH;REDDY, MVB;GUNASEKAR, D;MURTHY,

MM;CAUX, C; BODO, B; A new coumestan from

Tephrosiacalophylla


194-196

KRISHANAVENI, NS;SURENDRA, K;REDDY, MA;

NAGESHWAR, YVD; RAO, KR; Highly efficient reproduction

of aromatic acetals and neutral conditions using Beta-

cyclodextrin in water

Journal of Organic Chemistry 2003 68(5) : 2018-2019

KRISHNAVENI, NS;SURENDRA, K;NAGESWAR, YVD;RAO,

KR; Deoximation of oximes with 2-iodylbenzoic acid in

water in the presence of beta-cyclodextrin

Synthesis Stuttgart (2003) (13) : 1968-1970

KRISHNAVENI, NS;SURENDRA, K;NAGESWAR, YVD;RAO,

KR; Mild and efficient hydrolysis of aromatic thioacetals/

thioketals using o-iodoxybenzoic acid (IBX) in presence

beta- cyclodextrin in water


KOTAI, L;GACS, I;KAZINCZY, B;SAJO,IE;SREEDHAR, B;

Quasi-intramolecular acid-base reactions in aqueous

solutions of metal-Complexes of basic ligands I.

Generalized theoretical considerations on the

deammoniation of [MLm] X-n type ammonia complexes

Transition Metal Chemistry (2003) 28(3) : 292-295

KULSHRESTHA, UC;KULSHRESTHA, MONIKA J;SEKAR,

R;SASTRY, GSR; VAIRAMANI, M; Chemical characteristics

of rainwater at an urban site of south central India


153

KUMARASWAMY, G;RAMESH, S; Soaked Phaseolus

aureus L: an efficient biocatalyst for asymmetric

reduction of prochiral aromatic ketones

Green Chemistry (2003) 5(3) : 306-308

KUMARASWAMY, G;SASTRY, MNV;JENA, N;KUMAR,

KR;VAIRAMANI, M; Enantioenriched (S)-6,6 ‘-

diphenylbinol-Ca: a novel and efficient chirally modified

metal complex for asymmetric epoxidation of

alpha,beta-unsaturated enones

Tetrahedron-Asymmetry (2003) 14(23):3797-3803

KUMARASWAMY, G;DAS, AK;JENA, N; A reliable

multigram synthesis of (+/-) doxazosin

Organic Preparations and Procedures International(2003) 35(6) : 603-608

KUMARI, GN KRISHNA;ARAVIND, S;BALACHANDRAN,

J;GANESH, MR; SOUNDARYA DEVI, S;MALATHI,

R;RAVIKUMAR, K; Antifeedant neo-cleorodanes from

Teucrium tomentosum Heyne(Labiatae)

Phytochemistry (2003) 64(6) : 1119-1123

MADHAN, A;RAO, BV; Stereoselective synthesis of 1,4-

dideoxy-1,4-imino-D-allitol and formal Synthesis of

(2S,3R,4S)-3,4-dihydroxyproline


MADHAVI, G;KULKARNI, SJ;MURTHY, KVVSBSR; VISWA NATHAN, V;

RAGHAVAN, KV; Side-chain alkylation of 4-picoline with

formaldehyde over alkali-modified Zeolites


MAHENDER, G;RAMU, R;RAMESH, C;DAS, B; A simple and

facile chemo- and regioselective deprotection of

acetonides using silica supported sodium hydrogen

sulfate as a heterogeneous catalyst


MAHESWARI, R;SHANTHI, K;SIVAKUMAR, T;NARAYANAN,

S; Mesoporous molecular sieves: Part 1. Isopropylation

of naphthalene over AlMCM-41


MAHESWARI, R; HANTHI, K; IVAKUMAR, T; ARAYANAN, S;

Beckmann rearrangement over phosphotungstic acid/

SiMCM-41 cyclohexanone oxime to -caprolactam

Applied Catalysis A: General (2003) 248(1-2) 291-301

MANJULA, A; AO, BV; EELAKANTAN, P; One pot synthesis

of a -Aminophosphonates: An inexpensive approach


MANJULA, A;REDDY, GN;RAO, BV; Oxidative deoximation

with catalytic sodium tungstate


MEHTA, G;SINGH, SR;PRIYAKUMAR, UD;SASTRY, GN; The

tricyclo[2.1.0.02,5]pentan-3-one system: a new probe for

the study of -facial selectivity in nucleophilic additions


MEREYALA, HB;POLA, P; Controlled acetolysis of 3,6-

anhydro-5-o-benzyl-1,2-o- isoprophlidene-A-D

glucofuranose: Synthesis of 1-(3’,6’-anhydro-A-D-

glucofuranosyl) thymine


MEREYALA, HB;MAMIDYALA, SK;CHIGURUPATI, KP;

SRINIVASA, SR; Discriminative glycosylation of 3-

(aryloxy)propane-1,2-diols by choice of a glycosyl donor


MEREYALA, HB;BANTU, R; Synthesis of methyl 3-deoxy-

alpha/beta – D-ribofuranoside by regioselective reduct

ive opening of methyl 2,3-anhydro-alpha/beta-D-

ribofuranoside - Indian Journal of Chemistry Section B

Organic Chemistry Including Medicinal Chemistry

(2003) 42(12) : 3071-3074

MEREYALA, HB;POLA, P; Resolution of 1-Arylethylamines

with 5-(1,2-0-Isopropylidene-3,6-anhydro-alpha D-

glucofuranosyl) hydrogen phthalate


Publications

154


MOHAN, SR;RAO, A RAMAKRISHNA; Early identification

of innovative and market acceptable technologies: a

model for improving technology transfer capabilities

in public research institute

Journal of Scientific & industrial Research (2003)

62(9): 865-875

MOHAN, SR;KRISHNA, D;MURTHY, BSN;RAO, A

RAMAKRISHNA; Productivity evaluation of public

research institute using factor analysis

Industrial Engineering (2003) 32(9) : 22-28

MOHAN, SR; Technology incubators-A strategy for

commercializing knowledge of public R&D Institutes

Pharma Bio World (2003) 2(2) : 72-80

MOHAN, SR;MAHENDRANATH, D; Application of

statistical modeling in inventory management of a Ware

House

Industrial Engineering Journal (2003) 32(3) : 2-4

Mohan, SV;Sistla, S;Guru, RK;Prasad, KK;Kumar, CS;

Ramakrishna, SV;Sarma, PN; Microbial degradation of

pyridine using Pseudomonas sp. and isolation of Plasmid

responsible for degradation

Waste Management (2003) 23(2) : 167-171

MOHAN, SV;RAO, NC;PRASAD, KK;KARTHIKEYAN, J;

Erratum to “Treatment simulated reactive yellow 22

(Azo) dye effluents using Spirogyra species” [Waste

Management, 22(6) 575–582 (2002)]

Waste Management (2003) 23(2) : 195

MOHAN, SV;SARMA, PN; Hazardous waste management

and treatment technologies in pharmaceutical

industries

Pharma Bio World (2003) 2(4) : 134-140

MOHAN, SV;SARMA, PN; Selection of appropeiate

physiochemical treatment technologies for

pharmaceutical wastewater

Pharma bioworld (2003) 2(3) : 82-86

MESHARAM, HM;GANESH, YSS;MADHAVI, AV; ESHWARAIAH, B;

YADAV, JS;GUNASEKAR, D; Clay supported ammonium

nitrate “Clayan”: A new reagent for selective Nitration

of arenas


MESHRAM, HM;REDDY, GS;REDDY, MM;EESHWARAIAH,

B;YADAV, JS; Microwave thermolysis: Part III - A rapid

and convenient coupling of2-naphthols in solvent-free

condition

Indian Journal of Chemistry Section B, Organic

Chemistry Including Medicinal Chemistry (2003)

42(10) : 2615-2617

MIRZA, SP;KRISHNA, P;PRABHAKAR, S;VAIRAMANI,

M;GIBLIN, D; GROSS, L MICHAEL The kinetic method

reveals secondary deuterium isotope effects on the

proton affinity and gas-phase basicity of glycine and

alanine methyl esters

International Journal of Mass Spectrometry (2003)

230(2-3) : 175-183

MOHAN, K CHANDRA;RAVIKUMAR, K;SHETTY, MM;

Crystal structures of two substituted key intermediates

of phenothiazine Derivatives

Journal of Chemical Crystallography (2003) 33(2) :

97-103

MOHAN, K CHANDRA;RAVIKUMAR, K;SHETTY, MM;

THIYAGARAJAN, S; RAJAN, SS; Crystal and molecular

structures of 1,4-dihydro-6-methyl-5-N,N-diethyl

carbamoy l-4-phenyl-2(3H)-pyrimidinethion e (1) and

1,4-dihydro-6-methyl-5-N-methyl carbamoyl-4-(2 ‘-

nitrophenyl)-2(3H)-pyrimidinethione hemihydrate (2)

Journal of Chemical Crystallography (2003) 33(2) :

113-121

MOHAN,K CHANDRA;RAVIKUMAR, K;SHELLY, MM;

VELMURUGAN, D; Crystal and molecular structures of

4-aryl-1,4-dihydropyrimidines: Novel calcium channel

antagonists

Zeitschrift fur Kristallographie (2003) 218(1) : 46-55

155

MOHAN, SV;SARMA, PN; Anaerobic treatment process

for pharmaceutical wastewater

Pharma bioworld (2003) 2(1) : 101-108

MOIZUDDIN, Md;VENKATESWARLU, Ch; Temperature

Trajectory Tracking of a Chemical Reactor using Fuzzy

linguistic Controller

Indian Chemical Engineering Section A (2003) 45(2) :

84-87

MOULI, PC;MOHAN, SV;REDDY, SJ; A study on major

inorganic ion composition of atmospheric aerosols at

Tirupati

Journal of Hazardous Materials (2003) 96(2-3) : 217-228

MURTY, MSR;JYOTHIRMAI, B;KRISHNA, PR;YADAV, JS; Zinc

mediated alkylation of cyclic secondary amines


NACHARAYA, YV;WATTIAU, P;WERUTZ, S;BATHE,

S;MOHAN, SV;WILDERER, PA;HAUSNER, M; Dual labeling

of Psedomonas putida with fluroscent proteins for in

situ monitoring of conjugal transfer of TOL plasmid

Applied Environmental Microbiology (2003) 69(8) :

4846-4852

NAGARAJA, BM;KUMAR, VS;SHASIKALA, V;PADMASRI,

AH;SREEDHAR, B; RAJU, BD;RAO, KSR; A highly efficient

Cu/MgO catalyst for vapour phase hydrogenation of

furfural to furfuryl alcohol


NAGARAJU, V;SREENATH, D;RAO, JT;RAO, RN; Separation

and determination of synthetic impurities of

sildenafil(vliagra) by reversed-phase high-performance

liquid chromatography

Analytical Sciences (2003) 19(7) : 1007-1011

NAGRAPU, L;NARENDER, R;SUCHETA, K; Benzothiazepine

fused heterocycles VI: A convenient synthesis of 2-aryl-

4 (4-hydroxy-6-methyl-2-pyrone-3-yl)-2,3-dihydro-1, 5-

benzothiazepines using MCM-41(H) zeolite

Heterocyclic Communications (2003) 9(1) : 35-38

NARAYANAN, S; Selective hydrogenation of unsaturatedaldehydes and ketonesBulletin of the Catalysis Society of India (2003) 2 :107-121

NAIR, VIJAY;MATHEW, B;VINOD, AU;MATHEN, JS;ROS,S;MENON, RS; VARMA, R L SRINIVAS, R; [4+1] cycloadditionreactions of o-thioquinones with isocyanides: Novelsyntheses of 2-imino-1,3-oxathiolesSynthesis-Stuttgart (2003) (5) : 662-664

NAIR, VIJAY;SREEKANTH, AR;ABHILASH, N;BIJU, AT;DEVI,BR; MENON, RS;RATH, NP;SRINIVAS, R; Novel pyridine-catalyzed reaction of dimethyl acetylenedicarboxylatewith aldehydes and N-tosylimines: Efficient synthesisof 2-enzoylfumarates and 1-azadienesSynthesis-Stuttgart (2003) (12):1895-1902

NAIR, VIJAY;VINOD, N UNNI;RAJEEV, S ABHILASH;MENON,V;VARMA, SANTHI R LUXMI;VIJI, S;MATHEW,SAUMINI;SRINIVAS, R; Multicomponent reactionsinvolving zwitterionic intermediates for theconstruction of heterocyclic systems: one pot synthesisof aminofurans and iminolactonesTetrahedron (2003) 59(51) : 10279-10286

NAIR, VIJAY;BALAGOPAL, L;MENON, RS;ROS, S;SRINIVAS,R; Oxidative intramolecular cyclization reactions ofcinnamyl ethers mediated by cerium(IV) ammoniumnitrate (CAN): a stereoselective synthesis of 3,4-trans-disubstituted tetrahydrofuran derivativesArkivoc (2003) (Part 8):199-210

NANDA, S;YADAV, JS; Asymmetric synthesis of unnatural(Z,Z,E)-octadecatrianoid and Eicosatrienoid bylipoxygenase-catalyzed oxygenationTetrahedron: Asymmetry (2003) 14(13) : 1799-1806

NANDY, JP;PRABHAKARAN, EN;KUMAR, SK;KUNWAR,AC;IQBAL, J; Reverse turn induced pi-facial selectivityduring polyaniline-supported cobalt(II) salen catalyzedaerobic epoxidation of N-cinnamoyl L-proline derivedpeptides


1692

Publications

156


PALANIAPPAN, S;AMARNATH, CA; Pyridinium chloro

chromate oxidation route to polyaniline

Polymers for Advanced Technologies (2003) 14(2) :

122-128

PALANIAPPAN, S;NARENDER, P;SARAVANAN, C;RAO, VJ;

Polyaniline-supported sulfuric acid salt as a powerful

catalyst for the protection and deprotection of carbonyl

compounds

Synlett (2003) (12) : 1793-1796

PARTHASARATHY, G;CHOUDARY, BM;SREEDHAR,

B;KUNWAR, AC; SRINIVASAN, R; Ferrous saponite from

the Deccan Trap, India, and its application in Adsorption

and reduction of hexavalent chromium

American Mineralogist (2003) 88(11-12 Part 2):1983-1988

PARTHASARATHY, G;VAIRAMANI, M; Testin for fullernes

in geologic materials: Oklo carbonaceous substances,

Karelian shungites, Sudbury Black Tuff: Comment and

Reply

Geology (2003) : e32-e33

PRASAD, TEV;KUMAR, SS;GOUD, MBP;KUMAR,

PA;SRINIVAS, A;REDDY, PS;PRASAD, DHL; Bubble

temperature measurements on binary mixtures formed

by cyclohexane at 94.7 kPa

Journal of Chemical and Engineering Data (2003) 48(2)

: 351-353

PRASAD, TEV; KUMAR, BS; NAVEEN, PG;PRASAD, VVJ;

PRASAD, DHL; Boiling temperature measurements on

the binary mixtures of n-hexane with Some aliphatic

alcohols

Physics And Chemistry Of Liquids (2003) 41(1) : 39-43

PRASAD, TEV;RAMSERISH, GV;SATYAKISHORE, P;PRASAD,

DHL; Boiling Point Temperatures of the Binary Mixtures

of 1,3-Dimethylbenzene With Methanol, 1-Propanol or

2-Propanol at 95 kPa

Chemical Engineering Communications (2003) 190 :

171-176

NARENDER, N;MOHAN, KKVV;REDDY, RV;SRINIVASU,

P;KULKARNI, SJ; RAGHAVAN, KVLiquid phase

bromination of phenols using potassium bromide and

hydrogen Peroxide over zeolites


192(1-2) : 73-77

NARENDER, N;MOHAN,KVVK;KULKARNI, SJ;RAGHAVAN,

KV; Mild and regioselective oxidative bromination of

aromatic compounds using ammonium bromide and

oxone

Journal of Chemical Research – Part S (2003) (9) : 597-

598

NARSAIAH,AV;NAGAIAH, K; Antimony pentachloride-

promoted regeneration of carbonyl compounds from

oximes

Synthesis-Stuttgart (2003) (12) : 1881-1882

NARSAIAH, AV;NAGAIAH, K; Lanthanum chloride

mediated-regeneration of carbonyl compounds from

oximes in water - Indian Journal of Chemistry Section B

Organic Chemistry IncludingMedicinal Chemistry

(2003) 42(9) : 2045-2047

NARSAIAH, AV;NAGAIAH, K; An efficient Knoevenagel

condensation catalyzed by LaCl3 center dot 7H(2)O in

heterogeneous medium


NISHA, CK;BASAK, P;MANORAMA, SV;MAITI, S; JAYA

CHANDRAN, KN; Water-soluble complexes from random

copolymer and oppositely charged Surfactant. 1.

Complexes of poly(ethylene glycol)-based cationic

random Copolymer and sodium dodecyl sulfate

Langmuir (2003) 19(7) : 2947-2955

NOORJAHAN, M;REDDY, MP;KUMARI, VD;LAVÉDRINE,

B;BOULE; P;SUBRAHMANYAM, M Photocatalytic

degradation of H-acid over a novel TiO2 thin film fixed

bed Reactor and in aqueous suspensions

Journal of Photochemistry and Photobiology A:

Chemistry (2003) 156(1-3) : 179-187

157

PRASAD, TEV;SANKAR, B;KUMAR PAVAN;PRASAD, DHL;

Boiling temperature measurements on the binary

mixtures formed by tert-butanol with some chloretha

nes and chloroethylenes at 94.6 kPa

Fluid Phase Equilibria (2003) 213(1-2) : 147-152

PRIYAKUMAR, UD;SASTRY, GN; Measures to evaluate

heteroaromaticity and their limitations: Story of

skeletally Substituted benzenes - Proceedings Of The

Indian Academy of Sciences

Chemical Sciences (2003) 115(1) : 49-66

PRIYAKUMAR, UD;SASTRY, GN; Cation-interactions of

curved polycyclic systems: M+(M=Li and Na) ion

Complexation with buckybow


RADHAKRISHNA, P;KANNAN, V;SHARMA, GVM;RAO,

MHVR; Diastereoselective Baylis-Hillman reaction: Use

of sugar derived aldehydes as Chiral electrophiles

Synlett (2003) (6) : 888-889

RADHAKRISHNA, P;LAVANYA, B;SHARMA, GVM; Stereo

selective synthesis of C-phenyl - and -glycero hepto

pyranosides


RADHAKRISHNA, P;EMPATI RAJA SEKHAR;KANNAN, K;

The use of acetylenic aldehydes in Baylis–Hillman

reactions: synthesis of Versatile allyl propargyl alcohols


RADHAKRISHNA, P;REDDY, VVR;SHARMA, GVM; A

versatile protocol for the synthesis of oxazole and 3-

nitro/3-carbethoxy pyrrole C-nucleosides using TOSMIC

Synlett (2003) (11) : 1619-1622

RADHAKRISHNA, P;LAVANYA, B;JYOTHI, Y;SHARMA, GVM;

Radical-mediated diastereoselective synthesis of

benzothiazole sulfonyl Ethyl C-glycosides

Journal of Carbohydrate Chemistry (2003) 22(6) : 423-

431

RAGHAVAN, SADAGOPAN;ANURADHA, K; Solid-phase

synthesis of heterocycles from 1,4-diketone synthons

Synlett (2003) (5) : 711-713

RAGHAVAN, SADAGOPAN;JOSEPH, SC; The sulfinyl

moiety as an intramolecular nucleophile. Part 3:

Synthesis of (-)

Muricatacin Tetrahedron: Asymmetry (2003) 14(1) :

101-105

RAGHAVAN, SADAGOPAN;JOSEPH, SC; The sulfinyl

moiety as an internal nucleophile. Part 8: Efficient,

stereospecific Synthesis of (+)-polyoxamic acid


RAGHAVAN, SADAGOPAN;JOSEPH, SC; A novel and

stereospecific synthesis of (+)-exo-brevicomin


RAGHAVAN, SADAGOPAN;RAJENDER, A; Novel, short,

stereoselective synthesis of lyxo-(2R,3R,4R)-

phytosphingosine and Erythro-(2R,3S)- Sphingosine


7097

RAGHAVAN, SADAGOPAN;RAJENDER, A; RASHEED,

M ABDUL;REDDY, SR; Synthesis of tetrahydrofurans via

silicon promoted Pummerer type reaction


RAGHAVAN, SADAGOPAN;RAJENDER, A;YADAV,

JS; Novel, efficient and stereospecific synthesis of xylo-

(2R,3S,4S)-phytospingosine And Threo-(2R-3R)-

sphingosine


RAGHAVAN, SADAGOPAN;RASHEED, M ABDUL; Sulfinyl

moiety as an internal nucleophile. Part 6: Stereospecific

synthesis of 3-amino-2-hydroxy-4-phenylbutanoate -

Trahedron Asymmetry (2003) 14(10) : 1371-1374

Publications

158


RAMANA, GV;RAO, BV; Stereoselective synthesis of (-)-and (+)-pentenomycins using RCMTetrahedron Letters (2003) 44(27) : 5103-5105

RAMESH, CHIMMANI;BANERJEE, J;PAL, R;DAS, B; Studieson novel synthetic methodologies, Part 25-Silicasupported sodium Hydrogen Sulfate and amerlyst-15:Two efficient heterogenous catalysts for facilesynthesis of bis-and tris(1H-indol-3-yl)methanes fromindoles and carbonyl compoundsAdvanced Synthesis and Catalysis (2003) 345(5) : 557-559

RAMESH, CHIMMANI;MAHENDER, G;RAVINDRANATH,N;DAS, B; A mild, highly selective and remarkably easyprocedure for deprotection of Aromatic acetates usingammonium acetate as a neutral catalyst in aqueousMediumTetrahedron (2003) 59(7) : 1049-1054

RAMESH, CHIMMANI;MAHENDER, G;RAVINDRANATH,NASI;DAS, B; A simple, mild and efficient procedure forselective cleavage of prenyl esters Using silica-supported sodium hydrogen sulphate as aheterogenous catalystTetrahedron Letters (2003) 44(7) : 1465-1467

RAMESH, CHIMMANI;MAHENDER, G;RAVINDRANATH,NASI;DAS, B; A convenient, rapid, highly selective andeco-friendly method for deprotection of aryl acetatesUsing silica gel supported ammonium formate undermicrowave irradiationGreen Chemistry (2003) 5(1) : 68-70

RAMESH, CHIMMANI; RAVINDRANATH, NASI; DAS,B; Electrophilic substitution reactions of indoles withcarbonyl compounds using ceric ammonium nitrate: Anovel and efficient method for the synthesis of di-andtri-indolylmethanesJournal of Chemical Research-S (2003) (2) : 72-74

RAMESH, CHIMMANI; RAVINDRANATH, NASI; DAS,B; Simple, efficient and selective deprotection of phenolicmethoxymethyl ethers using silica-Supported sodiumhydrogen sulfate as a heterogenours catalyst(1)Journal of Organic Chemistry (2003) 68(18) : 7101-

7103

RAGHAVAN, SADAGOPAN;RASHEED, M ABDUL; A noveland stereospecific synthesis of (+)-preussinTetrahedron (2003) 59(51) : 10307-10312

RAGHAVAN, SADAGOPAN;REDDY, SR; The sulfinyl Moietyas an internal nucleophile 2.Stereoselective synthesisof (-)-Galantinic Acid via 1,3-asymmetric inductionThe Journal of Organic Chemistry (2003) 68(14) :5754-5757

RAGHAVAN, SADAGOPAN;REDDY, S RAMAKRISHNA;Practical, efficient, stereoselective, formal synthesis of(2R,3R,4R) 3-hydroxy-4-MethylprolineTetrahedron Letters (2003) 44(40) : 7459-7462

RAGHAVAN, SADAGOPAN;TONY, KA; Sulfinyl moiety asan internal nucleophile. 1. Efficient stereoselectivesynthesis of fragment a of cryptophycin 3Journal of Organic Chemistry (2003) 68(12) : 5002-5005

RAGHUNATH, P;SITHA, S;BHANUPRAKASH, K;CHOUDARY,BM; Formation of the silicon analogues of isocyanic acid,HNSiO, and its isomers by Neutral-neutral reactions ofthe fragments: A computational studyJournal of Physical Chemistry A (2003) 107(51) :11497-11504

RAHMAN, MF;SIDDIQUI, MKJ; Biochemical enzymeactivity in different tissues of rats exposed to o Novelphosphorothinoate - Journal of Environmental ScienceHealth Part BPesticides, Food Contaminants and Agriculture Waste(2003) 38(1) : 59-71

RAJGOPAL, K;KRISHNA KUMAR, RV;NANDHINI,MS;RAVIKUMAR, K; NATRAJAN, S; Bis (DL-alanine)tetraaquacobalt (ll) dinitrateActa Crystallographica , Section –C (2003) 59(Part-8): M562-M564

RAM, SR;CHARY, KP;SALAHUDDIN, S;IYENGAR, DS; Anefficient chemoselective production of amines fromazides using AlCl

3/NaBH

4

Indian Journal of Chemistry Section-B OrganicChemistry Including Medicinal Chemistry (2003) 42(4): 935-937

159

RAMESH, CHIMMANI; RAVINDRANATH, NASI;DAS,

B;PRABHAKAR, A; BHARATAM, J; RAVIKUMAR,

K; KASHINATHAM, A;McMORRIS, TC; Pseudoguainolides

from the flowers of Parthenium hysterophorus

Phytochemistry (2003) 64(4) : 841-844

RAMESH, CHIMMANI; RAVINDRANATH, NASI; RAM,

TEJOMOORTULA SIVA; DAS, B; Arylnaphthalide Lignans

from Cleistanthus collinus

Chemical & Pharmaceutical Bulletin (2003) 51(11) :

1299-1300

RANGANATHAN, S;KUNDU, D;VUDAYAGIRI, SD; Protein

evolution-intrinsic preferences in peptide-bond

formation-A computational and experimental-analysis

Journal of Biosciences (2003) 28(6) : 683-690

RAO, AG;PRASAD, K KRISHNA;NAIDU, GV;RAO,

CHANDRASHEKAR N; SARMA, PN; Removal of sulfide in

integrated anaerobic-aerobic wastewater treatment

system

Clean Technological Environmental Policy (2003) (6) :

66-71

RAO, AG;ANNAPURNA, JETTY; Purifying waste gas in

pharmaceutical industry

Pharma Bio World (2003) Feb-Apr : 84-89

RAO, AG;ANNAPURNA, JETTY; Biofilters promise better

odour removal in pharma industry

Pharma Bio World (2003) May-Jul : 87-91

RAO, AG;ANNAPURNA, JETTY; Biotechnological

processes for hydrogen sulfide removal from gaseous

streams

Pharma Bio Wold (2003) Aug-Oct : 141-144

RAO, JL;BHANUPRAKASH, K; Computational studies of

the non-linear optical properties of some three-

Dimensional molecules: effect of –– through bond

interaction on the first Hyperpolarizability

Synthetic Metals (2003) 132(3) : 315-324

RAO, JV;KAVITHA, P;RAO, AP; Comparative toxicity of

tetra ethyl lead and lead oxide to earthworms, Eisenia

fetida (Savigny)

Environmental Research (2003) 92(3) : 271-276

RAO, JV;KAVITHA, P;MAKKAPATI, AK; Efficacy of

imidacloprid gel (MAXFORCE® ) bait to control

cockroach infestation in food storage godowns

Pestology (2003) XXVII (2) : 7-12

RAO, JV;PAVAN, YS;MADHAVENDRA, SS; Toxic effects of

chlorpyrifos on morphology and acetylcholinesterase

activity in the earthworm, Eisenia foetida

Ecotoxicology and Environmental Safety (2003)

54(3) : 296-301

RAO, JV;RANI, CHS;KAVITHA, P;RAO, RN;MADHAVENDRA,

SS; Toxicity of Chlorpyrifos to the fish Oreochromis

mossambicus

Bulletin of Environmental Contamination &

Toxicology (2003) 70(5) : 985-992

RAO, JV; SHILPANJALI, D;KAVITHA, P;MADHAVENDRA,

SS; Toxic effects of profenofos on tissue acetylcholine

sterase and gill morphology in a Euryhaline fish,

Oreochromis mossambicus

Archives Of Toxicology (2003) 77(4) : 227-232

RAO, KN;LINGAIAH, N;SURYANARAYANA, I;PRASAD, PSS;

A comparison of structure and catalytic functionality

of 12-molybdophosphoric Acid and its ammonium salt

in the ammoxidation of 2-methylpyrazine to 2-

cyanopyrazine


RAO, K VENKATA SUBBA;RACHEL, A;SUBRAHMANYAM,

M;BOULE, P; Immobilization of TiO2 on pumice stone

for the photocatalytic degradation Of dyes and dye

industry pollutants

Applied Catalysis B: Environmental (2003) 46(1) :

77-85

Publications

160


RAO, RN;RAJU, DN;VENKATESWARLU, N;RAO, BV;

PARVATHI, N;MANJULA, A;REDDY, GN;GAWALI, PB;

SREEKANTH, M; RAO, PN; Development and validation

of a liquid chromatographic method for monitoring of

process-related synthesis organic impurities of

profenofos in technical products

Journal of Chromatographic Science (2003) 41(8) :

418-421

RAO, RN;VENKATESWARLU, N; KHALID, S;NARASIMHA, R;

Liquid chromatographic separation and determination

of aromatic Sulfonates in an aquatic environment using

a photodiode array and Electrospray ionization-mass

spectrometer as detectors Analytical Sciences

The International Journal Of The Japan Society For

Analytical Chemistry (2003) 19(4) : 611-615

RAO, RN;VENKATESWARLU,N;RAO, BV;RAJU, PVC;

KRISHNAIAH, A; Separation and determination of small

amounts of sulfur in technical Thiopharate-methyl by

reversed-phase high-performance liquid chromato

graphy

Journal of Separation Science (2003) 26(9-10) : 932-

934

RAO, VVVNSR;RAVIKANTH, S;REDDY, GV;MAITRAIE,

D;YADLA, R;RAO, PS; Microwave assisted intramolecular

Witting reaction: A facile method for the synthesis of

conjugated acetylenes


RAO, SHAILAJA, K;ACHAR, PN;RAHMAN, MF; Biochemical

changes induced in Liver and Serum of Diplodiatoxin

(Stenocarpella maydis) Treated Male and Female Rats

Drug and Chemical Toxicology (2003) 26(4) : 231-243

RATHNA; GVN;CHATTERJI, PR; Controlled drug release

from gelatin-sodium carboxymethylcellulose Inter

penetrating polymer networks - Journal of Macro

molecular Science

Pure & Applied Chemistry A40(6) : 629-639

RAO, K VENKATA SUBBA;KANDAVELU, V;SRINIVAS, B;SUBRAHMANYAM, M;THAMPI, KR; A novel route for the synthesis ofpiperazine from N-(2,3-dihydroxy propyl) ethylenediamine overcomposite photocatalystsChemical Communications (2003) (21) : 2706-2707

RAO, K VENKATA SUBBA;SRINIVAS, B;SUBRAHMANYAM, M; Titaniumoxide loaded zeolites as photocatalysts for the cyclization ofEthylenediamine with propylene glycolCatalysis Letters (2003) 90(1-2) : 95-102

RAO, K VENKATA SUBBA;SUBRAHMANYAM, M; BOULE, P;Photocatalytic transformation of dyes and by-productsin the presence of hydrogen-PeroxideEnvironmental Technology (2003) 24(8) : 1025-1030

RAO, MHV RAMANA;KUMAR, S KIRAN;KUNWAR, AC;Formation of b- hairpins in L-Pro-Gly containing peptidesfacilitated by 3-amine Benzoic acidTetrahedron Letters (2003) 44(39) : 7369-7372

RAO, PK;RAO, KSR;PADMASRI, AH; Transformation ofchlorofluorocarbons through catalytic HydrodehalogenationCattech (2003) 7(6) : 218-225

RAO, PR;REDDY, MN;RAMAKRISHNA, S;DIWAN, PV;Comparative in vivo evaluation of propranololhydrochloride after oral And transdermal administration in rabbitsEuropean Journal of Pharmaceutics andBiopharmaceutics (2003) 56(1) : 81-85

RAO, R JAGADEESHWAR;TIWARI, ASHOK K; KUMAR, USAMPATH; REDDY, S VENKAT;ALI, AMTUL Z;RAO, JMADHUSUDANANovel 3-O-acyl mesquitol analogues asfree-Radical scavengers and enzyme inhibitors:synthesis, biological evaluation and structure-activityrelationshipBioorganic and Medicinal Chemistry Letters (2003)13(16) : 2777-2780

RAO, RN;NAGARAJU, V; A overview of the recent trendsin development of HPLC methods for determination ofimpurities in drugsJournal of Pharmaceutical and Biomedical Analysis

(2003) 33(3) : 335-377

161

RAVIKANTH, V;REDDY, VLN;RAMESH, P;RAO, TP;DIWAN,

PV;KHAR, A;VENKATESWARLU, Y; Corrigendum to “An

immunosuppressive tryptophan-derived alkaloid from

Lepidagathis cristata” [Phyto chemistry 58 (2001) 1263–

1266]

Phytochemistry (2003) 62(2) : 243

RAVIKANTH, V; REDDY, VLN; REDDY, AV; DIWAN,

PV; VENKATESWARLU, Y; Diterpenes from the latex of

Euphorbia nivulia,


447-449

RAVIKANTH, V;REDDY, VLNR;REDDY, AV;KODELA,

R;TADIKAMALLA, VR;TEJOMOORTY, SR;KONDAPI,

AK;DIWAN, PV;VENKATESWARLU, Y; Three New Ingol

Diterpenes from Euphorbia nivulia: Evaluation of

Cytotoxic Activity


431-434

RAVINDRANATH, NASI;RAMESH, C;DAS,B; A rare

dinorditerpene from Jatropha curcas


431-432

RAVINDRANATH, NASI;RAMESH, C;KISHORE, KH;MURTY,

USN;DAS B; Clerodendrone, a novel hydroquinone

diterpenoid from Clerodendrum indicum

Journal of Chemical Research-S (2003) (7) : 440-441

RAVINDRANATH, NASI;RAMESH, C;REDDY, MR;DAS, B; A

facile and convenient three-component coupling

protocol for the synthesis of Pyrano and furoquinolines


RAVINDRANATH, NASI;VENKATAIAH, B;RAMESH,

C;JAYAPRAKASH, P;DAS, B; Jatrophenone, a Novel

Macrocyclic Bioactive Diterpene from Jatropha

gossypifolia


870-871

RAVINDRANATH, NASI;RAMESH, C;REDDY, MR;DAS, B;

Selective removal of n-boc protecting group from

aromatic amines using Silica gel-supported sodium

hydrogen sulfate and HY-zeolite a heterogeneous

catalysts

Advanced Synthesis & Catalysis (2003) 345(11):1207-

1208

RAVINDRANATH, NASI;RAMESH, C;REDDY, MR;SRINIVAS,

KVNS;DAS, B; Acetylation of camptothecins using

lithium bromide as catalyst


RAVIPRASAD, P;BHUVANESWARI, K;SASTRY, GSR;

Spectrophotometric determination of kerosone in

ground waters

Indian Journal of Environmental Protection (2003)

23(9) : 964-965

RAVIPRASAD, P;SASTRY, GSR;SARMA, PN;Studies on the

characterization and utilization of solid waste from a

battery Manufacturing industry

Pollution Research (2003) 22(1) : 73-75

REDDY, AV;RAVINDER, K;REDDY, VLN;GOUD,

TV; RAVIKANTH, V; VENKATESWARLU, Y; Zeolite

catalyzed synthesis of bis(indolyl) methanes

Synthetic Communications (2003) 33(21) : 3687-

36942

REDDY, AV;RAVINDER, K;REDDY, VLN;RAVIKANTH, V;

VENKATESWARLU, Y; Amberlyst-15catalyzed efficient

synthesis of 1,1-diacetates from aldehydes


REDDY, AV;RAVINDER, K;GOUD, TV;KRISHNAIAH, P;RAJU,

TV; VENKATESWARLU, Y; Bismuth triflate catalyzed

conjugate addition of indoles to-enones


REDDY, BM;GANESH, I;KHAN, A; Preparation and

characterization of In2O3-TiO2 and V2O5/In2O3-TiO2

Composite oxides for catalytic applications

Applied Catalysis A: General (2003) 248(1-2) : 169-180

Publications

162


REDDY, GV;RAO, VVVNS RAMA;MAITRAIE, D;RAVIKANTH,

S;YADLA, R; REDDY, SN;NARSAIAH, B;RAO, P SHANTHAN

Studies on the reaction of unsymmetrical trifluoro

methyl 1,2-phenylenediamine with various ketones

leading to novel fluorinated heterocycles

Journal of Fluorine Chemistry (2003) 124(2) : 203-209

REDDY, KM;MANORAMA, SV;REDDY, AR; Bandgap

studies on anatase titanium dioxide nanoparticles

Materials Chemistry and Physics (2003) 78(1) : 239-245

REDDY, KR;RAMESH, K; SEELA, KK; RAO, VV; CHARY, KVR

Alkylation of phenol with methanol over molybdenum

oxide supported on NaY zeolite


REDDY, KR;REDDY, CV;MAHESH, M;RAJU, PVK; REDDY, VV

NARAYANA; New environmentally friendly solvent free

synthesis of dihydropyrimidinones Catalysed by N-

butyl-N,N-dimethyl-phenylethylammonium bromide


REDDY, KR;BHASKAR, T;CHARY, KVR; Structure and

reactivity of molybdenum oxide catalysts supported

on LA203 Stabilized tetragonal ZrO2

Langmuir (2003) 19(26) : 10795-10802

REDDY, M ARJUN;SURENDRA, K;BHANUMATHI, N; RAO,

KR; Corrigendum to “Highly facile biomimetic

regioselective ring opening of epoxides to halohydrins

in the presence of

cyclodextrin”: [Tetrahedron 58 (2002) 6003]

Tetrahedron (2003) 59(13) : 2363

REDDY, MK; REDDY, MVB; GUNASEKAR, D; MURTHY, MM;

CAUX, C;BODO, B; A flavone and an unusual 23-carbon

terpenoid from Andrographis paniculata

Phytochemistry (2003) 62(8) : 1271-1275

REDDY, MVB;REDDY, MK;GUNASEKAR, D;MURTHY,

MM;CAUX, C;BODO, B; A new sesquiterpene lactone

from Bombax-Malabaricum


458-459

REDDY, BM;KHAN, A;YAMADA, Y;KOBAYASHI, T; LORIDANT,

S;VOLTA, JC; Raman and X-ray photo electron

spectroscopy study of CeO2-ZrO2 and V2O5/CeO2-ZrO2

catalysts

Langmuir (2003) 19(7) : 3025-3030

REDDY, BM;KHAN, A;YAMADA, Y;KOBAYASHI, T;

LORIDANT, S;VOLTA, JC; Structural Characterization of

CeO2-TiO2 and V2O5/CeO2-TiO2 Catalysts by Raman

and XPSTechniques

Journal of Physical Chemisty –B (2003) 107(22) : 5162-

5167

REDDY, BM;SREEKANTH, PM; An efficient synthesis of 1,5-

benzodiazepine derivatives catalyzed by a solid

Superacid sulfated zirconia


REDDY, BM;KHAN, A;YAMADA, Y;KOBAYASHI, T; Structural

characterization of CeO2-MO2 (M = Si4+, Ti4+, and Zr4+)

mixed oxides by Raman spectroscopy, X-ray photo

electron spectroscopy, and other techniques

Journal of Physical Chemistry B (2003) 107 (41):

11475-11484

REDDY, CS;SMITHA, G;CHANDRASEKHAR, S; ZrCl4 as a

mild and efficient catalyst for the one-pot conversion

of TBS and THP ethers to acetates


REDDY, GSN;PRAKASH, JSS;SRINIVAS, R;MATSUMOTO,

GI;SHIVAJI, S; Leifsonia-Rubra Sp-Nov and Leifsonia-Aurea

Sp-Nov. Psychrophiles from a pond In Antarctica

International Journal of Systematic and Evolutionary

Microbiology (2003) 53(JUL) : 977-984

REDDY, GV;BABU, PR;KOMARAIAH, P;ROY, KRRM;

KOTHARI, IL Utilization of banana waste for the

production of lignolytic and cellulolytic enzymes by

solid substrate fermentation using two Pleurotus

species (P. ostreatus and P. sajor-caju)

Process Biochemistry (2003) 38(10) : 1457-1462

163

REDDY, NK;RAO, KS;MULAY, VN; Magnetic behavior ofLa(0.5)Ka(0.5)Me(2)Fe(16)O(27) hexagonal ferritesJournal of Materials Science Letters (2003) 22(22) :1563-1565

REDDY, SV;RAO, RJ;KUMAR, US;RAO, JM; Highly efficientand convenient deprotection of methoxymethyl ethersand esters using bismuth triflate in an aqueous mediumChemistry Letters (2003) 32(11) : 1038-1039

REDDY, TJ;MIRZA, SP;SARADHI, UVRV;RAO, VJ;VAIRAMANI, M; Mass spectral studies of N,N-dialkylaminoethanolsRapid Communications in Mass Spectrometry (2003)17(7) : 746-752

REDDY, VL NIRANJAN;RAVINDER, KODELA;SRINIVASULU,MASUNA; GOUD, T VENKATESHWAR;REDDY, SM; SRUJANKUMAR, D;RAO, T PRABHAKAR;MURTY, U SURYANARAYANA; VENKATESWARLU, Y; Two new macrocyclicdiaryl ether heptanoids from Boswellia ovalifoliolataChemical and Pharmaceutical Bulletin (2003) 51(9) :1081-1084

REDDY, VL NIRANJAN;RAVIKANTH, V;JHANSILAKSHMI,VVNS;MURTY, U SURYANARAYANA;VENKATESWARLU, Y;Inhibitory activity of homoisoflavonoids fromCaesalpinia Sappan against Beauveria BassianaFitoterapia (2003) 74(6) : 600-602

SABITHA, G;REDDY, GS KIRAN KUMAR; REDDY, ChSRINIVAS;YADAV, JS; A novel TMSI-mediated synthesisof Hantzsch 1,4-dihydropyridines at ambientTemperatureTetrahedron Letters (2003) 44(21) : 4129-4131

SABITHA, G;REDDY, Ch SRINIVAS;REDDY, ChMEV;YADAV,JS; BiCl3-catalyzed diastereoselective intramolecular[4,2] cycloaddition Reactions leading to pyrazoneannulated new sulfur heterocyclesSynthetic Communications (2003) 33(17) : 3063-3070

SABITHA, G;REDDY, GS KIRANKUMAR;REDDY, ChSRINIVAS;YADAV, JS; One-pot synthesis ofdihydropyrimidinones using iodotrimethylsilane. Facileand new improved protocol for the Biginelli reaction atroom temperatureSynlett (2003) (6) : 858-860

SABITHA, G;REDDY, GSKIRANKUMAR;REDDY, ChSRINIVAS;FATIMA, N; YADAV, JS; Zr(NO3)(4) : A versatileoxidizing agent for aromatization of Hantzsch 1,4-dihydropyridines and 1,3,5-trisubstituted pyrazolinesSynthesis-Stuttgart (2003) (8) : 1267-1271

SABITHA, G;REDDY, GS KIRANKUMAR, RAJKUMAR,M;YADAV, JS; RAMAKRISHNA, KVS;KUNWAR, AC;Iodotrimethylsilane induced diastereoselectivesynthesis of tetrahydropyranones by a tandemknoevenagel – Michael reactionTetrahedron Letters (2003) 44(40) : 7455-7457

SABITHA, G;REDDY, GSKK;REDDY, KB;YADAV, JS;Vanadium(III) chloride-catalyzed preparation of beta-amino alcohols from epoxidesSynthesis-Stuttgart (2003) (15) : 2298-2300

SABITHA, G;REDDY, GS KIRANKUMAR;REDDY, KBHASKAR; YADAV, JS; Vanadium (III) chloride catalyzedBiginelli condensation: solution phase liberalGeneration of dihydropyrimidin-(2H)-onesTetrahedron Letters (2003) 44(34) : 6497-6499

SABITHA, G;REDDY, CS;SRIHARI, P;YADAV, JS; Stereoselective total synthesis of (+)-virol CSynthesis Stuttgart (2003) (17) : 2699-2704

SAIESWARI, A;PRIYAKUMAR, UD;SASTRY, G NARAHARI;On the use of NICS criterion to evaluate aromaticity inheteroaramatics involving III and IV row main groupelementsJournal of Molecular Structure: THEOCHEM (2003)

663(1-3) : 145-148

SAIRAM, M;PALANIAPPAN, S; Benzoyl peroxide oxidation

route to polyaniline salt and its use as catalyst in the

Esterification reaction


201(1-2) : 289-296

SAIRAM, M;SREEDHAR, B;RAO, DVM;PALANIAPPAN, S;

Synthesis and thermal degradation kinetics of cellulose

esters

Polymers for Advanced Technologies (2003) 14(7) :477-485

Publications

164

SESHADRI, PR;SELVANAYAGAM, S;VELMURUGAN,

D;RAVIKUMAR, K; SURESHBABU, AR;RAGHUNATHAN, R;

2 ‘-Benzoyl-1 ‘,2,2 ‘,3,4 ‘,5 ‘,6 ‘,6a ‘-octahydro-1H-indan-2-

spiro-3 ‘-(3 ‘ H-pyrrolizine)-1 ‘-spiro-3 ‘’-1H-indoline-1,2

‘’,3-trione


Online) (2003) 59(Part 10) : O1559-O1561


D;RAVIKUMAR, K SURESHBABU, AR;RAGHUNATHAN, R;

2 ‘-(p-Methoxybenzoyl)-1 ‘,2,2 ‘,3,5 ‘,6 ‘,7 ‘,7a ‘-octahydro-

1H-indan-2-spiro-3 ‘-(3 ‘ H-pyrrolizine)-1 ‘-spiro-3’’-1H-

indoline-1,2 ‘’,3-trione


Online) (2003) 59(Part 11) : O1783-O1785



1-Methyl-4 ‘-(3-nitropheny1)-1H-indole-3-spiro-2 ‘-

pyrrolidine-3 ‘-spiro-2 ‘’-indan-2,1 ‘’,3 ‘’ trione


Online) (2003) 59(Part 12):O2025-O2027

SHARMA, GVM;BEGUM, ASRA;REDDY, K RAVINDER;

SANKAR, A RAVI; KUNWAR, AC; Highly stereoselective

synthesis of furano-oxepanes: intramolecular nitrone

cycloaddition (INC) reactions on sugar derived 2-

substituted allylic ethers


SHARMA, GVM;CHANDRA MOULI, Ch; A total synthesis

of macrosphelides C and F from –(+)-arabinose


SHARMA, GVM;GOPINATH, T; Radical cyclisation

approach for the synthesis of (+) dihydro canaden

solide,(+) Dihydrosporothriolide and their C-3 epimers

from –xylose

Tetrahedron (2003) 59(34) : 6521-6530

SAMPATH KUMAR, U;APARNA, P;RAO, RJ;RAO, TP;RAO,

JM; 1-Methyl anthraquinones and their biogenetic

precursors from stereopermone personatum

Phytochemistry (2003) 63(8) : 925-929

SAMPATH KUMAR, U;APARNA, P;RAO, R JAGADEESHWAR;

RAO, T PRABHAKAR;RAO, J MADHUSUDANA Erratum to

“1-Methyl anthraquinones and their biogenetic

precursors from Stereospermum personatum”

Phytochemistry (2003) 64(4) : 907

SASTRY, G MADHAVI; Application of N-particle random

walk to geminate recombination of a hemeprotein With

a ligand

Chemical Physical Letters (2003) 379(5-6) : 547-554

SASTRY, G NARAHARI; Organic chemists conquer the

synthesis of C-60

Current Science (2003) 85(2) : 125-126

SATYANARAYANA, L;REDDY, KM;MANORAMA, SV;

Synthesis of nanocrystalline Ni1-x

CoxMn

xFe

2-xO

4: a

material for liquefied Petroleum gas sensing

Sensors and Actuators B : Chemical (2003) 89(1-2) :

62-67

SATYANARAYANA, L;REDDY, KM;MANORAMA, SV;

Nanosized spinel NiFe2O4: A novel material for the

detection of liquefied petroleum gas in air materials

Chemistry and Physics (2003) 82(1) : 21-26

SATYAVATHI, B;PATWARI, AN;RAO, M BHAGWANTH;

Regio-selective catalytic vapor phase alkylation of

aniline: Preparation of 2,6-diethylaniline




Spiro-[2-3‘]oxindole-spiro-[3-3’’]oxindole-4[p-methyl

benzyl]pyrrolidizine


Online) (2003) 59 (Part 10) : O1458-O1460


165

SHARMA, GVM;ILANGOVAN, A;NARAYANAN, VL;GURJAR,

MK; First synthesis of aza-calanolides- a new class of

anti-HIV active compounds

Tetrahedron (2003) 59(1) : 95-99

SHARMA, GVM;RAKESH;SUBHASH CHANDER,

A;GOVERDHAN REDDY,V; RAO, MHV RAMANA;KUNWAR,

AC; Radical reactions on enol-esters: facile synthesis of

3-ulosonic acid derivates And chiral spiroacetals


SHARMA, GVM;REDDY, CG;KRISHNA, PR; Zirconium(IV)

Chloride catalyzed new and efficient protocol for the

selective Cleavage of p-Methoxybenzyl ethers


4575

SHARMA, GVM;REDDY, CG;KRISHNA, PR; A simple and

efficient protocol for the deprenylation of ethers and

esters catalysed by Zirconium(IV) chloride-sodium

iodide

Synlett (2003) (11) : 1728-1730

SHARMA, GVM;REDDY, K RAVINDER;RADHAKRISHNA, P;

SANKAR, A RAVI;NARSIMULU, K;KUMAR, S KIRAN;

JAYAPRAKASH, P; JAYA PRAKASH, P;JAGANNADH,

B;KUNWAR, AC Robust Mixed 10/12 Helics promoted

by “Alternation chirality” in a New Family Of C-Linked

Carbo-beta-peptides


125(45) : 13670-13671

SHARMA, GVM;SRINIVAS, B;KRISHNA, PALAKODETY RADHA; A facile

zirconium(IV) chloride catalysed selective deprotection of t-

butyldimethylsilyl (TBDMS) ethers


SMITHA, B;SRIDHAR, S;KHAN, AA; Synthesis of and

characterisation of proton conducting polymer

membranes for fuel cells

Journal of Membrane Science (2003) 225(1-2) : 63-76

SREEDHAR, B;BHASKAR, V;SRIDHAR, CH;SRINIVAS,

T;KÓTAI, L; SZENTMIHÁLYI, K; Acylation of alcohols and

amines with carboxylic acids: a first report catalyzed by

iron(III) oxide-containing activated carbon


191(1) : 141-147

SRIDEVI, KV;VENKATESHAM, U;REDDY, AV; VENKATESWARLU, Y;

Chemical constituents of the red alga Nitophyllum marginata


335-337

SRIDEVI, S;CHAUHAN, AS;CHALASANI, KB;JAIN, AK;

DIWAN, PV; Enhancement of dissolution and oral

bioavailability of gliquidone with hydroxy Propyl-beta-

cyclodextrin

Pharmazie (2003) 58(11) : 807-810

SRIDHAR, S;PRASAD, KK;MURTHY, GS;RAO, AG, KHAN, AA;

Processing of composite industrial effluent by reverse

osmosis

Journal of Chemical Technology and Biotechnology

(2003) 78(10) : 1061-1067

SRIDHAR, S;SRINIVASAN, T;VIRENDRA, U;KHAN, AA;

Pervaporation of ketazine aqueous layer in production

of hydrazine hydrate by peroxide process

Chemical Engineering Journal (2003) 94(1) : 51-56

SRIDHAR, S;SUSHEELA, G;MURTHY, GS;VEERAIAH,

G;RAMKRISHNA, M; Pervaporation performance of

Deacetylated Chitosan membrane in the Dehydration

of Acetone

Journal of Polymer Materials (2003) 20(1) : 9-16

SRINIVAS, K;MAITRAIE, D;RAO, PS;NARSAIAH, B; A facile

synthesis of 4-oxo-1,2,3,4-tetrahydropyrido [3 ‘,2 ‘: 4,5]

furo[3,2-d] Pyridines: A new tricyclic heterocyclic ring

system

Indian Journal of Chemistry Section B - Organic

Chemistry Including Medicinal Chemistry (2003)

42(3) : 605-610

Publications

166

SRINIVAS, KVNS;DAS, B; 9-Methoxy-20-O-acetyl camptothecin, a minor new alkaloid from Nothapodites foetida

Biochemical Systematics and Ecology (2003) 31(1) :85-87

SRINIVAS, KVNS;DAS, B; Studies on Novel Syntheticmethodologies. Part 17. A highly convenient, efficient,And selective process for preparation of Esters andAmides from Carboxylic Acids Using Fe3+ - K-10Montmorillonite ClayJournal of Organic Chemistry (2003) 68(3) : 1165-1167

SRINIVAS, KVNS;MAHENDER, I;DAS, B; Efficient and rapidone-pot conversions of aldehydes into nitriles andketones into amides using silica chloride undermicrowave irradiationChemistry Letters (2003) 32(8) : 738-739

SRINIVAS, KVNS;MAHENDER, I;DAS, B; Silica chloride: Aversatile heterogeneous catalyst for esterification andTransesterificationSynthesis-Stuttgart (2003) (16) : 2479-2482

SRINIVAS, KVNS;RAO, YK;MAHENDER, I;DAS, B;RAMAKRISHNA, KVS; HARA KISHORE, K;MURTY, USN;Flavanoids from Caesalpinia pulcherrimaPhytochemistry (2003) 63(7) : 789-793

SRINIVAS, KVNS;MAHENDER, I;DAS, B; Selectivemonoacetylation of symmetrical diols and selectivemonodeacetylation of symmetrical diacetates using HY-zeolite as reusable heterogenous catalystSynlett (2003) (15) : 2419-2421

SRINIVAS, S;PRAKASHAM, RS;SARMA, PN; Aerobicfermentation of D.xylose present I sugarcane molasses

to ethanol by Clavispora opuntiae

Asian J Microbiol. Biotechnol Environmental Sciences

(2003) 5(3) : 367-368

SUNDER, MS;PRASAD, DHL; Phase equilibria of water plus

furfural and dichloromethane plus n-hexane

Journal Of Chemical And Engineering Data (2003)

48(2) : 221-223

SUNITA, M;RAO, DG; Bioconversion of mango processing

waste to fish-feed by microalgae Isolated from fruit

processing industrial effluents

Journal of Scientific & Industrial Research (2003)

62(4) : 344-347

SURENDRA, K;KRISHNAVENI, NSRILAKSHMI;NAGESWAR,

YVD; RAO, K RAMA; Highly Regioselective Ring Opening

of Oxiranes with Phenoxides in the presence of beta -

Cyclodextrin in Water


4995

SURENDRA, K;KRISHAVENI, N SRILAKSHMI;REDDY, M

ARJUN;NAGESHWAR, YVD;RAO, K RAMA; Mild oxidation

of alcohols with o-Iodoxybenzoic acid (IBX) in water/

acetone mixture in the presence of beta-cyclodextrin


2059

SURENDRA, K; KRISHNAVENI, N SRILAKSHMI; REDDY, M

ARJUN; NAGESWAR, Y V D; RAO, K RAMA; Highly Selective

Oxidative Cleavage of beta-Cyclodextrin-Epoxide/

Aziridine Complexes with IBX in Water


9121

SURESH, KI;SITARAMAM, BS;RAJU; Effect of copolymer

composition on the dynamic mechanical and thermal

bevaviour of butyl acrylate-Acrylonitrile copolymer

Macromolecular Materials and Engineering (2003)

288(12) : 980-988

SWAMY, NR;VENKATESWARLU, Y; Mild and efficient

method for regioselective ring opening of aziridines with

amines by Bismuth trichloride


SWAROOPA RANI, A;ANNAPURNA, JETTY; RAMA

KRISHNA, SV; Penicillin Production in continuous stirred

tank reactor by Penicillium chrysogenum Immobilized

in Agar

Chemical and Biochemical Engineering Quarterly

(2003) 17(2) : 119-122


167

THIMMA, REDDY T;REDDY, NS;TAMMISHETTI, S; Synthesis

and characterization of guar gum-graft-polyacryloni

trile

Polymers for Advanced Technologies (2003) 14(10) :

663-668

THIMMA, REDDY T;TAMMISHETTI, S; Study of complex

coacervation of gelatin with sodium carboxymethyl

guar gum: microencapsulation of clove oil and

sulphamethoxazole

Journal Of Microencapsulation (2003) 20(2) : 203-

210

TIETZE, LF;BELL, HP;CHANDRASEKHAR, S; Natural

product hybrids as new leads for drug discovery

[Review]

Angewandte Chemie International Edition (2003)

42(34) : 3996-4028

TIWARI, AK; Adverse effects of antioxidants


VARALA, R;ALAM, MM;ADAPA, SR; Chemoselective

Michael type addition of aliphatic amines to alpha,beta-

ethylenic Compounds using bismuth triflate catalyst

Synlett (2003) (5) : 720-722

VARALA, R;ALAM, MM;ADAPA, SR; Bismuth triflate

catalyzed one-pot synthesis of 3,4-dihydropyrimidin-2

(1H)-ones: An improved protocol for the Biginelli

reaction

Synlett (2003) (1) : 67-70

VAIRAMANI, M;GROSS, ML; G-Quadruplex formation of

thrombin binding aptamer detected by electrospray

inoization mass spectrometry


125(1) : 42-43

VENKATAIAH, B;RAMESH, C;RAVINDRANATH, N;DAS, B;

Charminarone, a seco-pseudoguaianolide from

Parthenium hysterophorus

Phytochemistry (2003) 63(4) : 383-386

VENUGOPAL, A;ALUJA, J;SCURRELL, MS; The water-gas

shift reaction over Au-based, bimetallic catalysts. The

Au-M (M= Ag, Bi, Co, Cu, Mn, Ni, Pb, Ru, Sn, Tl) on Iron (III)

oxide system


VIJAYARAGHAVAN, R;SURIANARAYANAN, M;RAGHAVAN,

KV; Studies on synthesis and characterization of charge

transfer polymerization of styrene and alkyl methacry

lates

Journal of Macromolecular Science-Pure & Applied

Chemistry (2003) A40(10):1057-1080

VOLETI, N;VAIRAMANI, M; Proton affinity differences

among three N-acetylhexosamines studied by the

kinetic method

Rapid Communications in Mass Spectrometry (2003)

17(10) : 1089-1091

WULFF, H;RAO, MM;SCHOLZ, F; Crystallographic Evidence

for the formation of a continuous series of mixed

0Crystals between NiO and LiNiO2

Chemistry of Materials (2003) 15(4) , 988-993

YADAV, JS;ANURADHA, K;REDDY, BV SUBBA;

EESHWARAIAH, B; Microwave-accelerated conjugate

addition of aldehydes to ,-unsaturated ketones


YADAV, JS;BABU, RS;SABITHA, G; Stereoselective total

synthesis of (+)-artemisinin,


YADAV, JS;BABU, R SATHEESH;SABITHA, G; Total synthesis

of (+) artemisinin

ARKIVOC (Gainesville, FL, United States) (2003) (3) :

125-139

YADAV, JS;GEETHA, V;RAJU, AK;GNANESHWAR, D;

CHANDRASEKHAR, S; The first total synthesis of the 6-

hydroxy-4E-sphingenines


Publications

168

YADAV, JS;RAJAIAH, G;RAJU, AK; A concise and stereoselective synthesis of both enantiomers of altholactoneand isoaltholactoneTetrahedron Letters (2003) 44(31) : 5831-5833

YADAV, JS;REDDY, BVS; Microwave-assisted rapidsynthesis of neurotransmitter release enhancerlinopiridine And its new analoguesSynthetic Communications (2003) 33(18) : 3115-3121

YADAV, JS;REDDY, BVS;BAISHYA, GAKUL; InBr3-[bmim]PF6: a novel and recyclable catalytic system for thesynthesis of 1,3-dioxane derivativesGreen Chemistry (2003) 5(2) : 264-266

YADAV, JS;REDDY, BVS;BAISHYA, GAKUL; Green protocolfor conjugate addition of thiols to alpha, beta-unsaturated ketones Using [Bmim] PF(6) IF (2) O systemJournal of Organic Chemistry (2003) 68(18) : 7098-7100

YADAV, JS;REDDY, BVS;BAISHYA, GAKUL; Indiumtribromide: A novel and highly efficient reagent for theconversion of Oxiranes to thiiranesSynlett (2003) (3) : 396-398

YADAV,JS; REDDY, BVS; BASAK, AK;NARSAIAH, AV; Aza-Michael reactions in ionic liquids. A facile synthesis ofbeta-amino compoundsChemistry Letters (2003) 32(11):988-989

YADAV, JS;REDDY, BVS;BASAK, AK;NARSAIAH, AV; [Bmim]PF

6 and BF

4 ionic liquids as novel and recyclable reaction

media for aromatic aminationTetrahedron Letters (2003) 44(10) : 2217-2220

YADAV, JS;REDDY, BVS;BASAK, AK;NARSAIAH, AV; [Bmim]BF

4 ionic liquid: a novel reaction medium for the

synthesis of -amino alcoholsTetrahedron Letters (2003) 44(5) : 1047-1050

YADAV, JS;REDDY, BVS;BASAK, AK;NARSAIAH, AV; Three-component coupling reactions in ionic liquids: Animproved protocol for the synthesis of 1,4-dihydropyridines

Green Chemistry (2003) 5(1) : 60-63

YADAV, JS;REDDY, BVS;ESHWARAIAH, B;SRINIVAS, M;

VISHNUMURTHY, P; Three-component coupling

reactions inionic liquids: a facile synthesis of a-

Aminononaitriles

New Journal of Chemistry (2003) 27(3) : 462-465

YADAV, JS;REDDY, BVS;GAYATHRI, KU;PRASAD, AR;

[Bmim] PF6/RuCl3 center dot xH(2)O: a novel and

recyclable catalytic system for the oxidative coupling

of beta-naphthols


YADAV, JS;REDDY, BVS;GEETHA, V; Scandium triflate

catalyzed thioglycosidation of glycals: A facile synthesis

of 2,3-Unsaturated thioglycopyranosides


YADAV, JS;REDDY, BVS;GNANESHWAR, D; InCl3

immobilized in ionic liquids: a novel and recyclable

catalytic system for tetrahydropyranylation and

furanylation of alcohols


YADAV, JS;REDDY, BVS;KONDAJI, G; InCl3-catalyzed [3+2]

cycloaddition reactions: A facile synthesis of trans-

dihydrobenzofurans and substituted cyclobutane

derivatives


YADAV, JS;REDDY, BVS;KONDAJI, G; Eco-friendly and

highly chemoselective 1,3-oxathio-and 1,3-

dithioacetalization of Aldehydes using ionic liquids


YADAV, JS;REDDY, BVS;KRISHNA, AD;SADASIV, K;CHARY,

CJ; Ceric(IV) ammonium nitrate: A novel reagent for the

synthesis of homoallyl alcohols


YADAV, JS;REDDY, BVS;KRISHNA, AD;SWAMY, T; InBr3-

catalyzed sulfonation of indoles: a facile synthesis of 3-

sulfonyl indoles



169

YADAV, JS;REDDY, BVS;RAJU, AK; [Bmim]BF4 ionic liquid:

A novel and recyclable reaction media for the synthesis

of homoallylic amines


YADAV, JS; REDDY, BVS; NARSIMHASWAMY, D; NARSIMULU,

K;KUNWAR, AC; LiClO4- or LiOTf-accelerated 1,3-dipolar

cycloaddition reactions: a facile synthesis of cis-fused

chromano[4,3-c]isoxazoles


YADAV, JS;REDDY, BVS;PARIMALA, G; LiClO4-catalysed C-

alkylation of pyrrole and indoles with aziridines and

epoxides

Journal of Chemical Research - S (2003) (2) : 78-81

YADAV, JS;REDDY, BVS;PREMALATHA, K; 1-Butyl-3-

methylimidazolium tetrafluoroborate ([Bmim]BF4) ionic

liquid: A novel and recyclable reaction medium for the

synthesis of vic-diamines


952

YADAV, JS;REDDY, BVS;RAJ, KS;PRASAD, AR; Room tempe rature

ionic liquids promoted three-component coupling reactions: a

facile synthesis of cis-isoquinolonic acids

Tetrahedron (2003) 59(10) : 1805-1809

YADAV, JS; REDDY, BVS; RAO, CV; REDDY, MS; Molecular

iodine-catalyzed highly stereoselective synthesis of

sugar acetylenes


YADAV, JS;REDDY, BVS; RAO, KV; RAJ, KS; PRASAD, AR;

KUMAR, SK; KUNWAR, AC;JAYAPRAKASH, P;JAGANNATH,

B; InBr3-catalyzed cyclization of glycals with aryl amines

Angewandte Chemie-International Edition (2003)

42(42) : 5198-5201

YADAV, JS;REDDY, BVS;RAO, MS;REDDY, PN; LiClO4-

catalyzed highly diastereoselective synthesis of cis-

aziridine carboxylates


YADAV, JS;REDDY, BVS; RAO, RS;NAVEENKUMAR, V;

NAGAIAH, K; Microwave-assisted one-pot synthesis of

2,4-disubstituted quinolines under solvent-free

conditions


YADAV, JS; REDDY, BVS; REDDY, CHS; RAJASEKHAR, K; Bmim] PF(6):

A Novel and Recyclable Ionic Liquid for Conversion of

Oxiranes to Thiiranes in Aqueous Media

The Journal of Organic Chemistry (2003) 68(6) : 2525-

2527

YADAV, JS;REDDY, BVS;REDDY, KB;GAYATHRI, KU;PRASAD,

AR; Glaser oxidative coupling in ionic liquids: an

improved synthesis of conjugated 1,3-diynes


YADAV, JS;REDDY, BVS;SUNITHA, V;REDDY, KS; Novel use

of Selectfluor ( TM) for the synthesis of cis-fused

pyranoand Furanotetrahydroquinolines


1206

YADAV, JS;REDDY, BVS;REDDY, JSS;RAO, RS; Aza-Diels–

Alder reactions in ionic liquids: a facile synthesis of

pyrano- and Furanoquinolines

Tetrahedron (2003) 59(9) : 1599-1604

YADAV, JS; REDDY, BVS; REDDY, KS; Ultrasound-

accelerated synthesis of chiral allylic alcohols promoted

by Indium metal

Tetrahedron (2003) 59(28) : 5333-5336

YADAV, JS;REDDY, BVS;REDDY, MS; Elemental iodine-

catalyzed coupling of alkynylsilanes with acid chlorides:

A facile synthesis of alpha,beta-acetylenic ketones

Synlett (2003) (11) : 1722-1724

YADAV, JS;REDDY, BVS;REDDY, MS;NIRANJAN, N;PRASAD, AR; Lewis

acidic chloroaluminate ionic liquids: Novel reaction media for

the Synthesis of 4-chloropyrans European

Journal of Organic Chemistry (2003) (9) : 1779-1783

Publications

170

YADAV, JS;REDDY, BVS;REDDY, PN;RAO, MS; Bi(OTf )(3)-

[Bmim]PF6: A novel and reusable catalytic system for

the synthesis of cis-aziridine carboxylates

Synthesis-Stuttgart (2003) (9) :1387-1390

YADAV, JS;REDDY, BVS;REDDY, MS;PARIMALA, G; InBr3-

catalyzed alkynylation and allylation of acid chlorides:

A facile Synthesis of alkynyl and allyl ketones


YADAV, JS;REDDY, BVS;REDDY, PSR;REDDY, KS;REDDY,

PN; A novel approach for the synthesis of dipyrrolyl

alkanols and dipyrrolyl alkylamines

Synlett (2003) (3) : 417-419

YADAV, JS;REDDY, BVS;SATHEESH, G; Bi(Otf )3-catalyzed

allylation of epoxides:a facile synthesis of homoallylic

alcohols


YADAV, JS;REDDY, BVS;SATHEESH, G; InBr3/Cu(Otf )2-

catalyzed C-alkylation of pyrroles and indoles with –

diazocarbonyl


YADAV, JS;REDDY, BVS;SATHEESH, G;PRABHAKAR,

A;KUNWAR, AC; Unprecedented InCl3-catalyzed

formation of cis-fused perhydrofuro[2,3-b]oxepines


YADAV, JS;REDDY, BVS;SREEDHAR, P; Three-component

one-pot synthesis of alpha-hydroxylamino phosphates

using ionic liquids

Advanced Synthesis and Catalysis (2003) 345(5) : 564-

567

YADAV, JS;SRINIVAS, C; Ring expansion approach for the

synthesis of the (3S,4S)-hexahydroazepine core of

balanol and ophiocordin

Tetrahedron (2003) 59(51) : 10325-10329

YADAV, JS; REDDY, BVS; SRINIVAS, M; Green protocol for

the O-H insertion of alpha-diazoketones with alcohols

And water using ionic liquid [bmim]BF4

Chemistry Letters (2003) 32(11):1060-1061

YADAV, JS;REDDY, BVS;SUNITHA, S; Efficient and eco-

friendly process for the synthesis of bis(1H-indol-3-

yl)methanes Using ionic liquids


352

YADAV, JS;REDDY, BVS;SWAMY, T; Bi(OTf )3-catalyzed

allylation of quinones with allyltrimethylsilane


YADAV, JS;REDDY, BVS;SWAMY, T; Bi(OTf )(3)-catalyzed a

facile conjugate addition of indoles to p-quinones:

synthesis of 3-indolyl quinines

Tetrahedron Letters (2003) 44(51): 9121-9124

YADAV, JS;REDDY, BVS;VISHNUMURTHY, P; LIBF4: a mild

a novel reagent for the O—H insertion reactions of-

diazoketones



171

ABBO, HS; TINTINCHI, SJJ; CHAND, S; PRASAD, R;

Investigation of [Ni{Me4Bzo2[14]aneN4}]Cl2 catalyzed

selective hydroxylation of phenol to catechol by H202

in the homogeneous medium


218(2) : 125-132

AMARNATH, CA; SARAVANAN, C;PALANIAPPAN, S;

Preparation of benzyl acetate using polyaniline salts as

catalysts – Part II

Polymers for Advanced Technologies (2004) 15(3): 18-

121

AMINABHAVI, TEJRAJ M;VIJAYA KUMAR NAIDU,

B;SRIDHAR, S; Computer simulation and comparative

study on the pervaporation separation characteristics

of sodium alginate and its blend membranes with

poly(vinyl alcohol) to separate aqueous mixtures of 1,4-

dioxane or tetrahydrofuran

Journal of Applied Polymer Science (2004) 94(4) :

1827-1840

ANITHA, K;MOHAN, SV;REDDY, S JAYARAMA; Develop-

ment of acetylcholinesterase silica sol–gel immobilized

biosensor—an application towards oxydemeton

methyl detection

Biosensors and Bioelectronics (2004) 20(4) : 848-856

ANJAIAH, SIDDAM;CHANDRASEKHAR, SRIVARI;GREE,

RENE Synthesis and preliminary use of novel acrylic

ester-derived task-specific ionic liquids


ANJAIAH, SIDDAM;CHANDRASEKHAR, S;GREE, RENE;

Carbon-Ferrier rearrangements in ionic liquids using

Yb(OTf )3 as catalyst


214(1) : 133-136

20042004200420042004 ANJAIAH, SIDDAM;CHANDRASEKHAR, S;GREE, RENE;

Stetter reaction in room temperature ionic liquids and

application to the synthesis of haloperidol

Advanced Synthesis and Catalysis (2004) 346(11) :

1329-1334

ANNAPURNA, JETTY;CHOWDARY, IP;LALITHA, G;

RAMAKRISHNA, SV; IYENGAR, DS; Antimicrobial activity

of euphorbia nivulia leaf extract

Pharmaceutical Botany (2004) 42(2) : 91-93

ANNAPURNA, JETTY;KRISHNA PRASAD, G;VENKAT

NAIDU, G;RAO, A GANGANI; Enumeration of anaerobic

bacteria from upflow anaerobic sludge blanket (uasb)

reactor for the treatment of chemical industry

wastewater

Asian Jl of Microbiol. Biotech. Env. Science (2004)

6(2) : 253-258

ANURADHA, V;SRINIVAS, PV;RAO, J MADHUSUDANA;

Isolation and synthesis of isodihydropiperlonguminine

Natural Product Research (2004) 18(3) : 247-251

BARUMATI, BABITA;REDDY, K MADHUSUDAN REDDY;

SUNKARA, V MANORAMA; Tailored conductivity

behavior in nanocrystalline nickel ferrite

Applied Physics Letters (2004) 85(14) : 2833-2835

BASAK, PRATYAY;MANORAMA, SUNKARA V; PEO-PU/PAN

semi-interpenetrating polymer networks for SPEs:

influence of physical properties on the electrical

characteristics

Solid State Ionics (2004) 167(1-2) : 113-121

BASAK, PRATYAY; MANORAMA, SUNKARA V; Poly

(ethylene oxide)–polyurethane/poly(acrylonitrile)

semi-interpenetrating polymer networks for solid

polymer electrolytes: vibrational spectroscopic studies

in support of electrical behavior

European Polymer Journal (2004) 40(6) : 1155-1162

Publications

172

BEGUM, GHOUSIA; Carbofuran insecticide induced

biochemical alterations in liver and muscle tissues of

the fish Clarius batrachus (linn) and recovery response

Aquatic Toxicology (2004) 66(1) : 83-92

BINDU, P HIMA;SASTRY, G MADHAVI;MURTY, US;SASTRY,

G NARAHARI; Structural and conformational changes

concomitant with the E1–E2 transition in H+K+-ATPase:

a comparative protein modeling study

Biochemical and Biophysical Research

Communications (2004) 319(2) : 312-320

BINDU, P HIMA;SASTRY, G MADHAVI;SASTRY, G

NARAHARI; Characterization of calcium and magnesium

binding domains of human 5-lipoxygenase

Biochemical and Biophysical Research

Communications (2004) 320(2) : 461-467

BHASKAR, G;SATISH KUMAR, V;RAO, B VENKATESWARA;

A short stereoselective synthesis of (-)-chloramphenicol

and (+)-thiamphenicol


BHOGA, UMADEVI;MALI, RS;ADAPA, SRINIVAS R; New

synthesis of linear furoquinoline alkaloids


BOSE, DS;KUMAR, RK;FATIMA, L; A remarkable rate

acceleration of the one-pot three-component cyclo-

condensation reaction at room temperature: An

expedient synthesis of mitotic Kinesin Eg5 inhibitor

monastrol

Synlett (2004) (2) : 279-282

CHAKRABORTY, TK; Crorepati Scientist


CHAKABORTY, TK;KRISHNA MOHAN, B;KUMAR, A

UDAY;PRABHAKAR, A;JAGADEESH, B; Synthesis of 3,4-

di-O-acylated glucose-derived furanoid sugar amino

acids (Gaa): Conformational analysis of a Leu-

enkephalin analog containing di-O-myristoylated Gaa


CHAKRABORTY, TK;SRINIVASU, P;SAKUNTHALA

MADHAVENDRA, S; KIRAN KUMAR, S;KUNWAR, AC;

Conformational studies of the linear homooligomers

of a glucose-derived furanoid sugar amino acid


CHAKRABORTY, TK;SRINIVASU, P;SAKUNTHALA

MADHAVENDRA, S;KIRAN KUMAR, S;KUNWAR, AC;

Conformational studies of the linear homooligomers

of a glucose-derived furanoid sugar amino acid (VOL

45, PG 3573, 2004)


CHAKRABORTY, TK;SRINIVASU, P;TAPADAR, S;MOHAN,

BK; Sugar amino acids and related molecules: Some

recent developments

Journal of Chemical Sciences (2004) 116(4) : 187-207

CHAKRABORTY; TK; GOSWAMI,K RAJIB; Synthesis of

(3R,4S,5S,9S)-3,5,9-trihydroxy-4-methylundecanoic acid

´-lactone


CHAKRABORTY, TK;TAPADAR, S;RAJU, TV;ANNAPURNA,

T;SINGH, H; Cyclic timers of chiral furan amino acids

Synlett (2004) : 2484-2488

CHAKRABORTY, TK;REDDY, VR;SUDHAKAR, G;KUMAR,

SU;REDDY, TJ; KUMAR, SK;KUNWAR, AC;MATHUR,

A;SHARMA, R;GUPTA, N;PRASAD, S; Conformational

studies of 3,4-dideoxy furanoid sugar amino acid

containing analogs of the receptor binding inhibitor of

vasoactive intestinal peptide

Tetrahedron (2004) 60(38) : 8329-8339

CHAKRABORTY, TK;SRINIVASU, P;RAO, R VENGAL;

KUMAR, S KIRAN; KUNWAR, AC; Conformational Studies

of Peptides Containing cis-3-Hydroxy-d-proline

The Journal of Organic Chemistry (2004) 69(21) :

7399-7402


173

CHANDRASEKAR, DURAIRAJ; RAMAKRISHNA, SISTLA;

DIWAN, PRAKASH V; A rapid, sensitive and validated

method for the determination of ondansetron in

human plasma by reversed-phase high-pressure liquid

chromatography

Arzneimittel-Forschung (2004) 54(10) : 655-659

CHANDRASEKHAR, K;CHARY, NS;KAMALA, CT;SUMAN

RAJ, DS; RAO, A SREENIVASA; Fractionation studies and

bioaccumulation of sediment-bound heavy metals in

Kolleru lake by edible fish

Environment International (2004) 29(7) : 1001-1008

CHANDRASEKHAR, K;KAMALA, CT;CHARY,NS; SASTRY,

ARK; RAO, T; NAGESWARA; VAIRAMANI, M; Removal of

lead from aqueous solutions using an immobilized bio

material derived from a plant bio mass

Journal of Hazardous Materials (2004) 108(1-2) : 111-

117

CHANDRASEKHAR, K;CHARY, NS;KAMALA, CT; ANJANEYULU, Y;

Utilization of plant metal interactions for environmental

management: from a general disbelief to universal

acceptance

Proceedings of the Indian National Science Academy,

Part B: Biological Sciences (2004) 70(1) : 13-30

CHANDRASEKHAR, K;GUPTA, KK;BHATTACHARYA,

S;CHAKRAVARTHY, S; The determination of gold in ore

samples by inductively coupled Plasma Optical Emission

Spectrometry

Atomic Spectroscopy (2004) 25(4) : 165-169

CHANDRASEKHAR, S;CHANDRASHEKAR, B;NAGENDRA

BABU, K;VIJEENDER; REDDY, K VENKATRAM; Reductive

etherification of carbonyl compounds with alkyl

trimethylsilylethers using polymethylhydrosiloxane

(PMHS) and catalytic B(C6F5)3


CHANDRASEKHAR, S;JAGADESWAR, V;NARSIHMULU,

Ch;SARANGAPANI, M; KRISHNA, DR;VIDYASAGAR, J;VIJAY,

DOLLY;SASTRY, G NARAHARI; Design, synthesis and

cytotoxic studies on the simplified oxy analog of

eleutherobin


14(14) : 3687-3689

CHANDRASEKHAR, S;MURTHY, J KRISHNA;RAO, PK;RAO,

K S RAMA; Studies on the modification of Pd/Al203 and

Pd/C systems to design highly active catalysts for

hydrodechlorination of CFC-12 to HFC-32


CHANDRASHEKAR, S;NAGENDRABABU, B;REDDY, M

VENKATA;SRIHARI, P;PRABHAKAR, A;JAGADEESH, B; Safe

and convenient reduction of Ä2 –Isoxazolines with

PHMS-Pd(OH)2/C

Synlett (2004) (7) : 1303-1305

CHANDRASEKHAR, S;NARSIHUMULU, Ch; CHANDRA

SHEKAR, G; SHYAMSUNDER; Pd/CaCO3 in liquid

poly(ethylene glycol) (PEG): an easy and efficient recycle

systems for partial reduction of alkynes to cis-olefins

under a hydrogen atmosphere

Tetrahedron Letters (2004) 45(11) 2421-2423

CHANDRASEKHAR, S;NARSIHMULU, Ch;REDDY, N RAMA

KRISHNA; SULTANA, S SHAMEEM; Asymmetric aldol

reactions in poly(ethylene glycol) catalyzed by -proline


CHANDRASEKHAR, S;NARSIHMULU, Ch;REDDY, N RAMA

KRISHNA;SULTANA, S SHAMEEM; l-Proline catalyzed

asymmetric transfer aldol reaction between diacetone

alcohol and aldehydes

Chemical Communications (Cambridge, England)

(2004) (21) : 2450-2451

CHANDRASEKHAR, S;NARSIHMULU, Ch;SARITHA,

B;SULTANA, S SHAMEEM; Poly(ethyleneglycol) (PEG): a

rapid and recyclable reaction medium for the DABCO-

catalyzed Baylis-Hillman reaction


Publications

174

CHARY, KVR;KUMAR, CHINTHALA PRAVEEN;RAO,

PENDYALA VENKAT; RAMANA;RAO, VATTIKONDA

VENKAT; Dispersion and reactivity of V2O

5 catalysts

supported on Al2O

3-ZrO

2


CHARY, KVR;RAJENDER REDDY, KONDAKINDI;KISHAN,

GURRAM; NIEMANTSVERDRIET, JW;MESTL, GERHARD;

Structure and catalytic properties of molybedenum

oxide catalysts supported on zirconia


CHARY, KVR;RAJENDER REDDY, KONDAKINDI;KUMAR;

CHINTHALA PRAVEEN;NARESH;DHACHAPALLY;RAO,

VATTIKONDA VENKAT;MESTL, GERHARD Characterizat-

ion and reactivity of molybdenum oxide catalysts

supported on Nb2O

5–TiO

2


223(1-2) : 363-369

CHARY, KVR;SEELA, KK;SAGAR, GV;SREEDHAR, B;

Characterization and reactivity of niobia supported

copper oxide catalysts

Journal of Physical Chemistry B (2004) 108(2) : 658-663

CHARY, KVR;SRI LAKSHMI, KATAR;RAO, P VENKAT

RAMANA;RAO, K SEETHA RAMA; PAPADAKI, MARIA;

Characterization and catalytic properties of niobia

supported nickel catalysts in the hydrodechlorination

of 1,2,4-trichlorobenzene


223(1-2) : 353-361

CHATTOPADHYAY, DK;KUMAR, DBR;SREEDHAR, B;RAJU,

KVSN; Thermal stability and dynamic mechanical

behavior of acrylic resin and acrylic Melamine coatings

Journal of Applied Polymer Science (2004) 91(1) : 27-34

CHATTOPADHYAY, DK;PANDA, SIVA SANKAR;RAJU, KVSN;

Properties of diamine chain extended polyurethane

urea coatings

Journal of the Japanese Society of Color Material

(2004) 77(12) : 540-547

CHANDRASEKHAR, S;NARSIHMULU, Ch;SULTANA, S

SHAMEEM;REDDY, M SRINIVASA; The first stereoselective

total synthesis of (6S)-5,6-dihydro-6-[(2R)-2-hydroxy-6-

phenylhexyl] -2H-pyran-2-one


CHANDRASEKHAR, S;PRAKASH, S;JAYA;SHYAMSUNDER,

T;RAMACHANDAR, T; Tantalum(V) chloride-catalyzed

ring opening of aziridines with aromatic amines


CHANDRASEKHAR, S;SHYAMSUNDER, T;CHANDRA

SHEKAR, G;NARSIHUMULU, C; Hydrogenation and

hydrogenolysis with Pd/C in poly(ethylene glycol) (PEG):

A practical and recyclable medium

Synlett (2004) (3) : 522-524

CHANDRASEKHAR, S;RAMACHANDAR, T;SHYAM

SUNDER, T; Applications of trivalent and pentavalent

tantalum in organic synthesis

Indian Journal of Chemistry Section B Organic

Chemistry including Medicinal Chemistry (2004) 43(4)

: 813-838

CHANDRASEKHAR, S;REDDY, Ch RAJI;CHANDRASHEKAR,

G; Tris(pentafluorophenyl) borane catalyzed Ferrier

azaglycosylation with Sulfonamides and carbamates


CHANDRASEKHAR, S;REDDY, MAREPALLY SRINIVASA;

JAGADEESH, BHARATAM; PRABHAKAR, ANABATHULA;

RAMANA RAO, MALLEM HV; JAGANNADH, BULUSU

Formation of a Stable 14-Helix in Short Oligomers of

Furanoid cis-beta-Sugar-Amino Acid

Journal of the American Chemical Societyy (2004)

126(42) : 13586-13587

CHARY, KVR; KUMAR, CHINTHALA PRAVEEN; MURALI, AYALURU;

TRIPATHI, AKHILESH;CLEARFIELD, ABRAHAM; Studies on catalytic

functionality of V2O5/Nb2O5 catalysts


216(1) : 139-146


175

CHATTOPADHYAY, DK;SREEDHAR, B;RAJU, KVSN; Effect

of chain extender on phase mixing and coating

properties of polyurethane ureas

IEC Phase Mixing and Coating Properties (2004) : A-H

CHAUHAN, AS;JAIN, NK;DIWAN, PV;KHOPADE, AJ;

Solubility enhancement of indomethacin with

poly(amidoamine) dendrimers and targeting to

inflammatory regions of arthritic rats

Journal of Drug Targeting (2004) 12(9-10) : 575-583

CHOUDHARY, BM; Preface


223(1-2) : 15

CHOUDARY, BM;JYOTHI, K;KANTAM, ML;SREEDHAR, B;

Achiral dihydroxylation of olefins by osmate (OsO42-)

stabilized on nanocystalline magnesium oxide

Advanced Synthesis & Catalysis (2004) 346(1) : 45-48

CHOUDARY, BM;JYOTHI, K;MADHI, S;KANTAM, ML;0

Allylation of aldehydes, aldimines and ring opening of

terminal aromatic epoxides by scandium triflate using

polyethylene glycol (PEG) as an efficient recyclable

medium

Synlett (2004) (2) : 231-234

CHOUDARY, BM;JYOTHI, K;ROY, M;KANTAM, ML;

SREEDHAR, B; Bifunctional catalysts stabilized on

nanocrystalline magnesium oxide for one-pot synthesis

of chiral diols


1471-1480

CHOUDARY, BM;KANTAM, ML;RANGANATH, KVS;

MAHENDER, K;SREEDHAR, B; Bifunctional nanocrystalline

MgO for chiral epoxy ketones via Claisen-Schmidt

condensation-asymmetric epoxidation reactions


126(11) : 3396-3397

CHOUDARY, BM;KANTAM, ML;RANGANATH, KVS;RAO,

KK; Hydrogen processing by FeIII-exchanged

montmorillonite: A unique geochemical protocol

Angewandte Chemie International Edition (2004)

44(2) : 322-325

CHOUDARY, BM;MADHI, S;KANTAM, ML;SREEDHAR,

B;IWASAWA, Y; Synthesis of surface organopalladium

intermediates in coupling reactions: The mechanistic

insight


126(8) : 2292-2293

CHOUDARY, BM;MADHI, S;KANTAM, ML;SREEDHAR,

B;IWASAWA, Y; Synthesis of surface organopalladium

intermediates in coupling reactions: the mechanistic

insight. [Erratum to document cited in CA140:321498]


126(21) : 6833

CHOUDARY, BM;REDDY, Ch VENKAT;VEDA PRAKASH,

B;BHARATHI, B;KANTAM, ML; Oxidation of secondary and

tertiary amines by a solid base catalyst


217(1-2) : 81-85

CHOUDARY, BM;SRIDHAR, C;KANTAM, ML;SREEDHAR, B;

Hydroxyapatite supported copper catalyst for effective

three-component coupling

Tetrahedron Letters (2004) 45(39) :7319-7321

CHOUDARY, BM;SRIDHAR, C;SATEESH, M;SREEDHAR, B;

Microencapsulated bismuth (III) triflate catalyst for

organic transformations

Journal of Molecular Catalysis A-Chemical (2004)

212(1-2) : 237-243

CHOUDARY, BM;SOMESHWAR, T;LAKSHMI KANTAM,

M;REDDY, Ch VENKAT; Molybdate-exchanged Mg–Al–

LDH catalyst: an eco-compatible route for the synthesis

of -bromostyrenes in aqueous medium


Publications

176

DAS, B;HOLLA, HARISH;MAHENDER, GURRAM;BANERJEE,

JOYDEEP; REDDY, M RAVINDER; Hypervalent iodine-

mediated interaction of aldoximes with activated

alkenes including Baylis-Hillman adducts: a new and

efficient method for the preparation of nitrile oxides

from aldoximes


DAS, B;MAHENDER, GURRAM;KUMAR, VOOTURI

SUNIL;CHOWDHURY, NIKHIL; Chemoselective deprotect-

ion of trityl ethers using silica-supported sodium

hydrogen sulfate


DAS, B;REDDY, M RAVINDER;RAVINDRANATH, N;REDDY,

V SAI;VENKATESWARLU, K A; simple and efficient

tetrahydropyranylation using N-bromosuccinamide

Indian Journal of Chemistry B (2004) 43 B : 1711-

1712

DAS, B;REDDY, M RAVINDER;REDDY, V SAIDI;RAMU, R;

Novel and efficient Lewis acids as catalysts for single

step synthesis of pyrano and furnoquinolines


DAS, B;REDDY, V SAIDI;REDDY, M RAVINDER; An efficient

and selective tosylation of alcohols with p-toluene

sulfonic acid


DAS, B;REDDY, V SAIDI; ZrCl4 as an efficient catalyst for

selective tosylation of alcohol’s with p-toluenesulfonic

acid


DAS, B;SRINIVAS, KVNS;MAHENDER, I;RAVINDRANATH,

N;RAMESH, C; A convenient method for the preparation

of 7-cyanocamptothecins and 7-cyanom appicine

ketones


DANADEVI, K;ROZATI, R;BANU, BS;GROVER, P; Genotoxic

evaluation of welders occupationally exposed to

chromium and nickel using the comet and

micronucleus assays

Mutagenesis (2004) 19(1) 35-41

DANADEVI, K;ROZATI, R;BANU, B SALEHA;GROVER, P; In

vivo Genotoxic effect of nickel chloride in mice

leukocytes using comet assay

Food And Chemical Toxicology (2004) 42(5) : 751-757

DAS, B;BANERJEE, JOYDEEP; Silica supported sodium

hydrogen sulfate and amberlyst-15: Two efficient and

heterogeneous catalysts for single-step synthesis of 4

(3H)-quinazolines from anthranilic acid, orthoesters and

amines under solvent free conditions


DAS, B;BANERJEE, JOYDEEP;MAHENDER, GURRAM;

MAJHI, A; Organic reactions in water: An efficient Zinc

mediated stereoselective synthesis of (E)-and(Z)-

trisubstituted alkenes using unactivated alkyl halides

Organic Letters (2004) 6( 19) : 3349-3352

DAS, B;BANERJEE, JOYDEEP;MAJHI, ANJOY;MAHENDER,

GURRAM; An efficient stereoselective synthesis of (E)-

and (Z)-trisubstituted alkenes from unactivated Baylis–

Hillman adducts using NaBH4/CuCl

2·2H

2O


DAS, B;BANERJEE, JOYDEEP;RAVINDRANATH, NASI; A

simple and facile stereoselective synthesis of (Z)- and

(E)-allyl halides catalyzed by silica supported sodium

hydrogen sulfate: factors influencing the yields and

stereochemistry of allyl halides

Tetrahedron (2004) 60(38) : 8357-8361

DAS, B; BANERJEE, JOYDEEP; RAVINDRANATH, NASI;

VENKATAIAH, BOLLU; Convenient and efficient

stereoselective synthesis of (2Z)-2-(chloromethyl)alk-2-

enoates using iron(III) or indium(III) chloride



177

DAS, B;VENKATESWARLU, K;MAHENDER, G;HOLLA, H;

Synthesis of coumarins via a Pechmann condensation

using heterogeneous catalysts

Journal of Chemical Research (2004) (12) : 836-837

DAS, R;REDDY, V SAIDI;VENKATESWARLU, K;DAS, B; New

anhydroporthenin analogues from Parthenium

hysterophorus

Indian Journal of Heterocyclic Chemistry (2004)

14(1) : 59-60

DAS, PIYALI;SREELATHA, T;GANESH, ANURADDA; Bio oil

from pyrolysis of cashew nut shell-characterization and

related properties

Biomass and Bioenergy (2004) 27(3) : 265-275

DEVI, SS;MALATHI, R;RAJAN, SS;ARAVIND, S;KRISHNA

KUMARI, GN;RAVIKUMAR, K; A neo-clerodane diterpene

from Teucrium tomentosum

Acta Crystallographica Section E (Structure Rep.

Online) (2004) 60(Part 1) : 0117-0119

DINADAYALANE, TC; DEEPA, S; REDDY, A SRINIVAS; SASTRY,

G NARAHARI; Density functional theory study on the

effect of substitution and ring annelation to the rim of

corannulene


8111-8114

DINADAYALANE, TC;PRIYAKUMAR, UD;SASTRY, GN;

Exploration of C6H6 potential energy surface: A

computational effort to unravel the relative stabilities

and synthetic feasibiligy of new benzene isomers

Journal of Physical Chemistry A (2004) 108(51) :

11433-11448

FADNAVIS, NW;RADIHIKA, R KASIRAMAN ;Enantio- and

regiospecific reduction of ethyl 4-phenyl-2,4-dioxo

butyrate with baker’s yeast: preparation of (R) HPB ester


FADNAVIS, NW;RADHIKA, R KASIRAMAN;MADHURI, KV;

Gelozymes in organic synthesis Part 3: Lipase mediated

synthesis of enantiomerically pure ( R ) – and (S) –

enantiomers of 2-acetoxy-4-phenyl-(E)-but –3-enenitrile

Tetrahedron : Asymmetry (2004) 15(3) : 549-553

GANGADASU, B;PALANIAPPAN, S;RAO, VJ; One-pot

synthesis of dihydropyrimidinones using polyaniline-

bismoclite complex. A facile and reusable catalyst for

the Biginelli reaction

Synlett (2004) (7) : 1285-1287

GANGADASU, B.; NARENDER, P.; RAJU, B. CHINA; RAO, V.

JAYATHIRTHA; ZrCl4 catalyzed solvent free synthesis of

coumarins


GANESH, I;JOHNSON, R;MAHAJAN, YR;KHAN,

A;MADHAVENDRA, SS;REDDY, BM; Microwave-induced

combustion synthesis of nanocrystalline TiO2-SiO

2

binary oxide material

Journal of Materials Research (2004) 19(4) : 1015-

1023

GARCIA, A;PRABHAKAR, S;BROCK, CJ;PEARCE, AC;DWEK,

RA;WATSON, SP;EBESTREIT, HF;ZITZMANN, N; Extensive

analysis of the human platelet proteome by two-

dimensional gel electrophoresis and mass

spectrometry

Proteomics (2004) (4) : 656-668

GARCIA, A;PRABHAKAR, S;HUGHAN, S;ANDERSON,

TW;BROCK, CJ; PEARCE, AC;DWEK, RA;WATSON,

SP;HEBESTREIT, HF;ZITZMANN, N; Differential proteome

analysis of TRAP-activated platelets: involvement of

DOK-2 and phosphorylation of RGS proteins

Blood (2004) 103 : 2088-2095

Publications

178

JAGADEESH, B;DEMCO, DE;BLUMICH, B; Surface induced

order and dynamic heterogeneity in ultra thin polymer

films: A 1H multiple-quantum NMR study

Chemical Physics Letters (2004) 393(4-6) : 416-420

JAGADEESH, B;PRABHAKAR, A;RAO, MHV RAMANA;

MURTY, CVS;PISIPATI, VGKM;KUNWAR, AC;BOWERS, CR;

Probing anisotropic environment of thermotropic

liquidcrystal using 129Xe NMR spectroscopy

Journal of Physical Chemistry – B (2004) 108(31) :

11272-11279

JAGANNADH, B;REDDY, SS;THANGAVELU, RP;

Conformational preferences of 1,4,7-

trithiacyclononane: a molecular mechanics and density

functional theory study

Journal of Molecular Modeling (2004) 10(1) : 55-59

JAMIL, K;SHAIK, AP;MAHBOOB, M;KRISHNA, D; Effect of

organophosphorus and organochlorine pesticides

(monocrotophos, chlorpyriphos, dimethate and

endosulfan) on hum lymphocytes in vitro

Drug and Chemical Toxicology (2004) 27(2) : 133-144

JAYALAKSHMI, M;RAO, M MOHAN;CHOUDARY, BM;

Identifying nano SnS as a new electrode material for

electrochemical capacitors in aqueous solutions

Electrochemistry Communications (2004) 6(11) :

1119-1122

KAMAL, A;CHOUHAN, GAGAN; Investigations towards

the chemoselective thioacetaliztion of carbonyl

compounds by using ionic liquid [bmim]Br as a

recyclable catalytic medium


582

GOPINATH, RAJESH;LINGAIAH, N;BABU, N

SESHU;SURYANARAYANA, I;SAI PRASAD, PS;OBUCHI,

AKIRA; A highly active low Pd content catalyst

synthesized by deposition–precipitation method for

hydrodechlorination of chlorobenzene


223(1-2) : 289-293

GOVIND, MM;SELVANAYAGAM, S;VELMURUGAN, D;

RAVIKUMAR, K; SURESH BABU, AR; RAGHUNATH, R; 1-(2-

Chlorophenyl)-1H-indan-2-spiro2’-pyrrolizidine-3’-spiro-

3’’-1H-indole-1,3,2’’ (2H,3’’H)-trione


Online) (2004) 60(Part 1) : 054-056


D;RAVIKUMAR, K;SURESH BABU, AR;RAGHUNATH, R;

1-benzoylacenaphthylene-1-spiro-3’-pyrrolizidine-2’-

spiro-3’’-1H-indole-2,2’’ (1H,3’’ H)-dione

Acta Crystallographica Section E (Stru Rep Online)

(2004) 60(Part 1):057-059


D;RAVIKUMAR, K;SURESHBABU, AR;RAGHUNATHAN, R;

1‘-(4-methoxybenzoyl)acenaphthene-1-spiro-3 ‘-

pyrrolizidine-2 ‘-spiro-3’’-1H-indole-2,2 ‘’(1H,3 ‘’ H)-dione

Acta Crystallographica, Section E (Stru Reports Online)

(2004) 60(Part 5) :O873-O875



1 ‘ -methyl -4 ‘ -phenylacenaphthene-1-spi ro-2 ‘ -

pyrrolidine-3 ‘-spiro-2‘’-indan-2,1 ‘’ 3 ‘’,-trione

Acta Crystallographica, Section E (Stru Rep Online)

(2004) 60(Part4):O547-O549

HEMA, R;PARTHASARATHI, V;RAVIKUMAR, K;SARKUNAM,

K; NALLU, M; Dimethyl 3-benzoyl-7-(N,N-dimethy

lamino)indolizine-1,2-dicarboxylate

Acta Crystallographica, Section E (Stru Rep Online)

(2004) 60(Part-4):O479-O480


179

KAMAL, A;CHOUHAN, GAGAN; Chemoenzymatic

synthesis of enantiomerically pure 1,2-diols employing

immobilized lipase in the ionic liquid [bmim]PF6


KAMAL, A;KUMAR, B ASHWINI;ARIFUDDIN, M;PATRICK,

MIDOUX; An efficient and facile nitration of phenols with

nitric acid/zinc chloride under ultrasonic conditions

Ultrasonics Sonochemistry (2004) 11(6) : 455-457

KAMAL, A; LAXMAN, E; KHANNA, GB RAMESH; REDDY,

PSMM; TASNEEM, REHANA; ARIFUDDIN, M; NEELIMA, K;

KONDAPI, ANAND K; DASTIDAR, SUNANDA G; Design,

synthesis, biological evaluation and QSAR studies of

novel bisepipodophyllotoxins as cytotoxic agents

Bioorganic and Medicinal Chemistry (2004) 12(15) :

4197-4209

KAMAL, A; RAMANA, A VENKATA; REDDY, K SRINIVAS

A; RAMANA, K VENKATA; HARI BABU; A; RAJENDRA

PRASAD, B; One pot conversion of azido arenes to N-

arylacetamides and N-arylformamides: synthesis of 1,4-

benzodiazepine-2,5-diones and fused

[2,1-b]quinazolinones


KAMAL, A;RAMESH, G;SRINIVAS, O;RAMULU, P; Synthesis

and antitumour activity of pyrene-linked pyrrolo

[2,1-c][1 and 4] benzodiazepine hybrids


14(2) : 471-474

KAMAL, A; RAMESH, G; SRINIVAS, O; RAMULU, P; LAXMAN, N; REHANA,

TASNEEM; DEEPAK, M; ACHARY, MS; NAGARAJARAM, HA; Design,

synthesis, and evaluation of mixed imine-amine pyrroloben

zodiazepine dimers with efficient DNA binding affinity and

potent cytotoxicity

Bioorganic & Medicinal Chemistry (2004) 12(20) :

5427-5436

KAMAL, A; SHAIK, AHMAD ALI; SANDBHOR, M; MALIK,

M SHAHEER; Synthesis of enantiopure-azidoalcohols

from their ketoazides by reduction with NaBH4 in the

presence of alumina and in situ lipase resolution


KAMAL, A;REDDY, PSMM;REDDY, RAJASEKHAR D; The

effect of C2-fluoro group on the biological activity of

DC-81 and its dimmers

Bioorganic & Medicinal Chemistry Letters (2004)

14(10) : 2669-2672

KAMAL, A;REDDY, K LAXMA;REDDY, G SURESH

KUMAR;REDDY, BS NARAYAN; Selective reduction of

aromatic azides with hexamethyldisilathiane: synthesis

of new 2-azidopyrrolo[2,1-c][1,4]benzodiazepines


KAMAL, A;RAJENDRA PRASAD, B;VENKATA RAMANA,

A;HARI BABU, A; REDDY, K SRINIVAS; FeCl3–NaI mediated

reactions of aryl azides with 3,4-dihydro-2H-pyran: a

convenient synthesis of pyranoquinolines


KAMAL, A;RAMULU, P;SRINIVAS, O;RAMESH, G;KUMAR, P

PRAVEEN; Synthesis of C8-linked pyrrolo[2,1-c][1,4]

benzodiazepine-benzimidazole conjugates with

remarkable DNA-binding affinity


14(18) : 4791-4794

KAMAL, A;RAMU, R;KHANNA, GB RAMESH;SAXENA, AJIT

KUMAR; SHANMUGAVEL, M;PANDITA, RENU MOTI ;

Pyrrolo[2,1-c][1,4]benzodiazepine-antraquinone

conjugates. Synthesis, DNA binding and cytotoxicity


14(19) : 4907-4909

Publications

180

KAMAL, A;REDDY, PSMM;REDDY, D RAJA SEKHAR;LAXMAN, E;MURTHY, YLN; Synthesis of fluorinatedanalogues of SJG-136 and their DNA-binding potentialBioorganic & Medicinal Chemistry Letters (2004)14(22) : 5699-5702

KAMAL, A;SHAIK, AHMAD ALI;SANDBHOR, MAHENDRA;MALIK, M SHAHEER; KAGA, HARUMI; Chemoenzymaticsynthesis of (3S,4S)- and (3R,4R)-3-methoxy-4-methylaminopyrrolidineTetrahedron Letters (2004) 45(43) : 8057-8059

KAMAL, A; SHAIK, AHMAD ALI; SANDBHOR, MAHENDRA;MALIK, M SHAHEER; Chemoenzymatic synthesis of (R)-and (S)-tembamide, aegeline and denopamine by a one-pot lipase resolution protocolTetrahedron: Asymmetry (2004) 15(24) : 3939-3944

KANNAN, V; Diazabicyclo[2.2.2]octane – DABCO;Synlett (2004) (6) : 1120-1121

KANTAM, ML;AZIZ, KHATHIJA;LIKHAR, PRAVIN R; Bis(cyclopentadienyl) zirconium dichloride for alkylationof heteroaromatics and synthesis of bis(indolyl)methanes


KANTAM, ML;NEEREJA, V;KAVITA, B;HARITHA, Y; Cu(acac)

(2) immobilized in ionic liquids: A novel and recyclable

catalytic system for aziridination of olefins using

PhI=NTs as nitrene donor

Synlett (2004) (3) : 525-527

KANTAM, ML;NEELIMA, B;REDDY, CV;CHAUDHURI,

MK;DEHURY, SK; VO(acac)(2) supported on titania: a

heterogeneous protocol for the selective oxidation of

sulfides using TBHP


KANTI, P;SRIGOWRI, K;MADHURI, J;SMITHA, B;SRIDHAR,

S; Dehydration of ethanol through blend membranes

of chitosan and sodium alginate by pervaporation

Separation and Purification Technology (2004) 40(3) :

259-266

KAMAL, A;REDDY, K SRINIVASA;PRASAD, B RAJENDRA;HARI BABU, A; VENKATA RAMANA, A; Microwaveenhanced reduction of nitro and azido arenes to N-arylformamides employing Zn-HCOONH

4: synthesis of

4(3H)-quinazolinones and pyrrolo[2,1-c][1,4] benzodia-zepinesTetrahedron Letters (2004) 45(34) : 6517-6521

AMAL, A;SANDBHOR, MAHENDRA;ALI SHAIK, AHMAD;Chemoenzymatic synthesis of (S) and ( R )-propranololand sotalol employing one-pot lipase resolutionprotocolBioorganic and Medicinal Chemistry Letters (2004)14(17) : 4581-4583

KAMAL, A;SRINIVAS, O;RAMULU, P;RAMESH, G;KUMAR, PPRAVEEN; Synthesis of C8-linked pyrrolo[2,1-c][1,4]benzodiazepine-acridone/acridine hybrids aspotential DNA-binding agentsBioorganic and Medicinal Chemistry Letters (2004)14(15) : 4107-4111

KAMAL, A;SRINIVAS, O;RAMULU, P;RAMESH, G;KUMAR, PPRAVEEN; KUMAR, M SHIVA; Synthesis and DNA bindingaffinity of novel A-C

8/C-C

2-exo unsaturated alkoxyami

do- linked pyrrolo[2,1-c][1,4]benzodiazepine dimmersBioorganic and Medicinal Chemistry (2004) 12(16) ;4337-4350

KAMAL, A; REDDY, K LAXMA;DEVAIAH, V; SHANKARAIAH,N; Facile and efficient solid-phase synthesis of DNA-Interactive pyrrolo[2,1-c][1,4] benzodiazepinesSynlett (2004) (10) : 1841-1843

KAMAL, A;REDDY, K LAXMA;DEVAIAH, V;SHANKARAIAH,N; Synthesis of DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepines by employing polymer-supportedreagents:Preparation of DC-81 - Synlett (2004) (14) : 2533-2536

KAMAL, A;REDDY, K LAXMA;DEVAIAH, V;SHANKARAIAH,N;REDDY, Y NARASIMHA; A; new approach for the solid-phase synthesis of pyrrolo[2,1-c][1,4]benzodiazepinesinvolving reductive cleavageTetrahedron Letters (2004) 45(41) : 7667-7669


181

KARMALI, PRIYA P; KUMAR, VALLURIPALLI V;CHAUDHURI,

ARABINDA ; Design, syntheses and in vitro gene delivery

efficacies of novel mono-, di- and trilysinated cationic

lipids: a structure-activity investigation

Journal of Medicinal Chemistry (2004) 47(8) : 2123-2132

KIRUMAKKI, SHARATH R;NAGARAJU, N;CHARY,

KOMANDUR, VR; NARAYANAN, SANKARASUBBIER;

A facile O-alkylation of 2-naphthol over zeolites H, HY

and HZSM5 using dimethyl carbonate and methanol


KIRUMAKKI, SHARATH R;NAGARAJU, N;NARAYANAN,

SANKARASUBBIER; A comparative esterification of

benzyl alcohol with acetic acid over zeolites H, HY and

HZSM5


KRISHNA, GP;REDDY, RS;RAGHUNATH, P;BHANU

PRAKASH, K;KANTAM, ML; CHOUDARY, BM; A

computational study of ligand interactions with

hafnium and zirconium metal complexes in the liquid-

liquid extraction process

Journal of Physical Chemistry B. 108(19) : 6112-6120

KRISHNAIAH, P; REDDY, VLN; VENKATARAMANA,

G; RAVINDER, K; SRINIVASULU, M;RAJU, TV;RAVIKUMAR,

K; CHANDRASEKAR, D;RAMAKRISHNA, S; VENKATES

WARLU ET AL. New Lammellarin alkaloids from the

Indian Ascidian Didemnum obscurum and their

antioxidant properties

Journal of Natural Products (2004) 67(7) : 1168-1171

KRISHNA MOHAN, KVV;NARENDER, N;SRINIVASU,

P;KULKARNI, SJ;RAGHAVAN, KV; Novel bromination

method for anilines and anisoles using NH 4Br/H2O

2 in

CH3COOH


KRISHNA MOHAN, KVV;NARENDER, N;KULKARNI, SJ;

Simple and regioselective oxyiodination of aromatic

compounds with ammonium iodide and Oxone®


KRISHNAVENI, NS;SURENDRA, K;NARENDER,

M;NAGESWAR, YVD;RAO, KR; Highly efficient

regioselective ring opening of aziridines to beta-

haloamines in the presence of beta-cyclodextrin in water


KRISHNAVENI, NS;SURENDRA, K;RAO, KR; A simple and

highly selective biomimetic oxidation of alcohols and

epoxides with N-bromosuccinimide in the presence of

beta-cyclodextrin in water

Advanced Synthesis & Catalysis (2004) 346(2-3) :346-

350

KRISHNAVENI, NS; SURENDRA, K; REDDY, MS; NAGESWAR,

YVD; RAO, KR; Synthesis of thiranes from oxiranes in

the presence of beta-cyclodextrin in water


397

KULKARNI, SJ;KRISHNA MOHAN, KVV;RADHA RANI,

V;NARENDER, N;RAGHAVAN, KV; Synthesis of

heterocyclic three-fused ring compounds using

molecular sieve catalysts

Studies in Surface Science and Catalysts (2004) 154 C

: 2781-2787

KULKARNI, SJ;SRINIVASU, P;RAGHAVAN, KV; Fast and

efficient synthesis of zeolites under high pressure

Studies in Surface Science and Catalysis (2004)

154 A : 184-188

KULSHRESTHA, UC;RAO, T NAGESWARA;AZHAGUVEL, S;

KULSHRESTHA, MJ; Emissions and accumulation of

metals in the atmospheres due to crackers and sparkles

during Diwali festival in India


KUMAR, D NAVEEN;RAO, B VENKATESWARA; Asymmetric

synthesis of (1R,1’R,5’R,7’R) and (1S,1’R,5’R,7’R)-1-

hydroxy-exo-brevicomin and a formal synthesis of (+)-

exo-brevicomin


Publications

182

KUMAR POTLURI, SRINAGESH;RAGHU RAMULU,A;PARDHASARADHI, M; Synthesis of new unsymmetricaloptically active (s)-(+)-naproxen dendrimersTetrahedron (2004) 60(48) : 10915-10920

KUMAR, V SIVA;NAGARAJA, BM;SHASHIKALA, V; SEETHARAMULU, P;PADMASRI, AH;RAJU, B DAVID;RAO, KS RAMA;Role of acidic and basic sites of Al

2O

3 in predicting the

reaction pathway of isophorone transformationJournal of Molecular Catalysis A: Chemical (2004)223(1-2) : 283-288

KUMAR, V SIVA; NAGARAJA, BM; SHASHIKALA, V; PADMASRI, AH;MADHAVENDRA, S SHAKUNTALA;RAJU, B DAVID;RAO, KS RAMAHighly efficient Ag/C catalyst prepared by electro-chemicaldeposition method in controlling microorganisms in waterJournal of Molecular Catalysis A: Chemical (2004) 223(1-2) :313-319

KUMARA SWAMI, G;NIVEDITA, J;SASTRY, MNV;ASHOKKUMAR, B; An expeditions, practical large scale synthesisof 4-amino-2-chloro-6,7-dimethoxyquinazolineOrganic Preparations and Procedures International(2004) 36(4) : 341-345

LINGAIAH, BPV;REDDY, G VENKAT;YAKAIAH, T;NARSAIAH,B;REDDY, SN;YADLA, R;RAO, P SHANTHAN Efficient andconvenient method for the synthesis of polyfunctionalised 4H-PyransSynthetic Communications (2004) 34(23) : 4431-4437

LUCKE, B;NARAYANA, KV;MARTIN, A;JAHNISCH, K;Oxidation and ammoxidation of aromaticsAdvanced Synthesis and Catalysis (2004) 346(12) :1407-1424

MADHAVI, G;KULKARNI, SJ;RAGHAVAN, KV; Side-chainalkylation of heterocyclic compounds over modifiedzeolitesJournal of Molecular Catalysis A: Chemical (2004) 154C : 2760-2766

MAHBOOB, M;SIDDIQUI, MKJ; Effects of a novelorganophosphorus pesticide (RPV-V) on eutra hepaticdetoxifying enzymes after repeated oral doses in rats

Toxicology (2004) 202 : 159-164

KUMAR, D NAVEEN;RAO, B VENKATESWARA; A chironapproach to (1R,2R,5S,7R)-2-hydroxy-exo-brevicomin, acomponent of the volatiles produced by the malemountain pine beetle, Dendroctonus ponderosaeTetrahedron Letters (2004) 45(41) : 7713-7714

KUMAR, HMS;RAO, M SHESHA;CHAKRAVARTHY, PPAWAN;YADAV, JS; Enzymatic resolution of N-arylaziridine carboxylatesTetrahedron : Asymmetry (2004) 15(1) : 127-130

KUMAR, HMS;CHAKRAVARTHY, P PAWAN; RAO, MSHESHA; JOYASAWAL, SIPAK;YADAV, JS; Solid phasesynthesis of hydroxy benzothiazepinones throughcyclative release under thermolysis.Chemistry Letters (2004) 33(7) : 888-889

KUMAR, K KOTHAKONDA;BOSE, DS; Synthesis of a noveltetrahydroisoquinolino[2,1-c][1,4] benzodiazepine ringsystem with DNA recognition potentialBioorganic and Medicinal Chemistry Letters (2004)14(17) : 4371-4373

KUMAR, K KOTHAKONDA;BOSE, DS; The firstenantiomerically pure synthesis of (S)- and ( R )-Naftopidil utilizing hydrolytic kinetic resolution of (+)-(a-Naphthyl) Glycidyl etherChemistry Letters (2004) 33(9) : 1212-1213

KUMAR, MK; PRABHAKAR, S; KUMAR, MR; REDDY,TJ; PREMSINGH, S; RAJAGOPAL, S; VAIRAMANI, M;Coordination chemistry of chromium-Salen complexesstudied by electrospray ionization mass spectrometryRapid Communications in Mass Spectrometry: RCM(2004)18(10) : 1103-1108

KUMAR, M RAVI;PRABHAKAR, S;KUMAR, M KIRAN;REDDY,T; JAGADESHWAR;VAIRAMANI, M; Negative ionelectrospray ionization mass specral study ofdicarboxylic acids in the presence of halide ionsRapid Communications in Mass Spectrometry: RCM(2004)18(10) : 1109-1115

KUMAR POTLURI, SRINAGESH;RAGHU RAMULU, A;PARDHA SARADHI, M; Synthesis of new unsymmetricalpolyarylester dendrimersTetrahedron (2004) 60(17) : 3739-3744


183

MAHESH, M;VENKATESHWAR REDDY, Ch;SRINIVASA

REDDY, K;RAJU, PVK; NARAYANA REDDY, VV; Imino Diels-

Alder reactions: Efficient synthesis ofpyrano and

furoquinolines catalyzed by ZrCl4


MAHIDHAR, YENUGONDA VENKATA;RAJESH,

MUKTHAVARAM;CHAUDHURI, ARABINDA Spacer-arm

modulated gene delivery efficacy of novel cationic

glycolipids: design, synthesis, and in vitro transfection

biology

Journal of Medicinal Chemistry (2004) 47(16) : 3938-

3948

MAHIDHAR, YENUGONDA VENKATA; RAJESH, MUKTHA VARAM;

MADHAVENDRA, SS;CHADHURI, ARABINDA; Distance of hydroxyl

functionality from the quaternized center influence DNA

binding and in vitro gene delivery efficacies of cationic lipids

with hydroxyalkyl headgroups

Journal of Medicinal Chemistry (2004) 47(23) : 5721-

5728

MAJETI, BHARAT KUMAR; SINGH, RAJKUMAR SUNIL; YADAV,

SUDHEER KUMAR; BATHULA, SURENDAR REDDY;RAMAKRISHNA,

SISTLA; DIWAN, PV; MADHA VENDRA, SURKARA SAKUNTHALA;

CHAUDHURI, ARABINDA; Enhanced intravenous transgene

expression in mouse lung using cyclic-head cationic lipids

Chemistry & Biology (2004) 11(4) : 427-437

MANJULA, A;RAO, BV;NEELAKANTAN, P; An inexpensive

protocol for Biginelli reaction


MEREYALA, HB;BASEERUDDIN, MOHD;REDDY K

SREENIVASULU; Formal synthesis of furanodictine B

from D-glucose


MEREYALA, HB;FATIMA, LIYAKAT; PALLAVI, POLA;

Resolution of 1-arylalkylamines with 6-(1,2:3,4-di-O-

isopropylidene- galactopyranosyl) hydrogen phthalate


MEREYALA, HB;MAMIDYALA, SREEMAN KUMAR; Simple

entry into isonucleosides: synthesis of 6-amino-9-

[ ( 3 S , 4 S , 5 R ) - 4 - h y d r o x y - 5 - ( h y d r o x y m e t h y l )

tetrahydrofuran-3-yl] purine


MEREYALA, HB;MAMIDYALA, SREEMAN KUMAR; The

synthesis of [([beta-D-ribofuranosyloxy) methyl]

nucleosides Nucleosides,

Nucleaotides & Nucleic Acids, (2004) 23(4) : 655-669

MEREYALA, HB;BHAVANI, S;RUDRADAS, AP; Directing

effect of axial and equatorial anomeric substituent in

site specific glycosylation of glucopyranosides


MEREYALA, HARI BABU; POLA, PALLAVI; Controlled

Acetolysis of 3,6-Anhydro-5-O-benzyl-1,2-O-isopropy

lidene-a-D-glucofuranose: Synthesis of 1-(3',6'-Anhydro-

a-D-glucofuranosyl)thymine


MESHRAM HM;PREMALATHA K;RAMESHBABU K;

EESHWARAIAH B;YADAV JS; Zirconium(IV) chloride

catalyzed cyclization of ortho-allylphenols: Synthesis of

2-methyl-2,3-dihydrobenzofurans

Synthetic Communications (2004) (17) : 3091-3097

MIRZA, SHAMA PARVEEN;RAJU, N PRASADA;

MADHAVENDRA, SS;VAIRAMANI, M ; 5-Amino-2-

mercapto-1,3,4-thiadizole: a new matrix for the efficient

matrix-assisted laser desorption/ionization of neutral

carbohydrates

Rapid Communications in Mass Spectrometry: RCM

(2004) 18(14) : 1666-1674

MIRZA, SHAMA PARVEEN;RAJU, N PRASADA;VAIRAMANI,

M ; Estimation of the proton affinity values of fifteen

matrix-assisted laser desorption/ionizaion matrices

under electrospray inoizaion conditions using the

kinetic method

Journal of the American Society for Mass

Spectrometry (2004) 15(3) : 431-435

Publications

184

MURTHY, J KRISHNA;CHANDRA SHEKAR, S; RAO, KS

RAMA;KISHAN, G;NIEMANTSVERDRIET, JW; Advantages

of FCCA and Bi promotion in Bi-Pd/FCCA catalysts for

the hydrodechlorination of CCl2F

2


MURTHY, J KRISHNA;CHANDRA SHEKAR, S;PADMASRI,

AH;VENUGOPAL, A; SIVA KUMAR, V;NAGARAJA,

BM;SHASHIKALA, V;RAJU, B DAVID;RAO, P KANTA; RAO,

KS RAMA; Promotional effect of magnesia addition to

active carbon supported Pd catalyst on the

characteristics and hydrodechlorination activity of

CCl2F

2


MURTY, US;PRAVEEN, B;SATYA KUMAR, DVR;SRIRAM,

K;RAO, K MADHUSUDHAN;SAI, KSK; A baseline study of

rural Bancroftian filariasis in southern India

Southeast Asian Journal of Tropical Medicine and

Public Health (2004) 35(3) : 583-586

NAGARAJA, BM;KUMAR, V SIVA;SHASHIKALA,

V;PADMASRI, AH;REDDY, S SREEVARDHAN;RAJU, B

DAVID;RAO, KS RAMA; Effect of method of preparation

of copper – magnesium oxide catalyst on the

dehydrogenation of cyclohexanol


223(1-2) : 339-345

NAGAVENI, V;PRABHAKAR, S;VAIRAMANI, M;

Differentiation of Underivatized diastereomeric

hexosamine monosaccharides and their quantification

in a mixture using the kinetic method under

electrospray ionization conditions

Analytical Chemistry (2004) 76(13) : 3505-3509

NARASHIMAMURTHY, J;RAM RAO, AR;SASTRY, GN;

Aromatase inhibitors: A new paradigm in breast cancer

treatment

Current Medicinal Chemisty Anti-Cancer Agents (2004)

4(6) : 523-534

MOHAN, SV;BHASKAR, YV;KARTHIKEYAN, J; Biological

decolourisation of simulated azo dye in aqueous phase

by algae Spirogyra species

International Journal of Environment and Pollution

(2004) 21(3) : 211-222

MOHAN, SV;SIRISHA, K;RAO, N CHANDRA SEKHARA;

SARMA, PN;REDDY, S JAYARAMA Degradation of

chlorpyrifos contaminated soil by bioslurry reactor

operated in sequencing batch mode: bioprocess

monitoring

Journal of Hazardous Materials (2004) 116(1-2) : 39-

48

MOHAN, SV;KARTHIKEYAN, J; Adsorptive removal of

reactive azo dye an aqueous phase onto charfines and

activated carbon

Clean Technological Environ Policy (2004) 6 : 196-200

MOULI, PC;KUMAR, MP;REDDY, S JAYARAMA;MOHAN, SV;

Monitoring of air pollution in Indian metropolitan cities:

Modelling and quality indexing

International Journal of Environment and Pollution

(2004) 21(4) : 365-382

MOULI, PC;MOHAN, SV;REDDY, S JAYARAMA;

Electrochemical processes for the remediation of

wastewater and contaminated soil: Emerging

technology

Journal of Scientific and Industrial Research (2004)

63(1) : 11-19

MURTHY, BSN;RAO, R NAGESWARA; Global optimization

for prediction of blend composition of gasolines of

desired octane number and properties

Fuel Processing Technology (2004) 85(14) : 1595-1602

MURTHY, J KRISHNA;CHANDRA SHEKAR, S;KUMAR, V

SIVA;RAJU, B DAVID; SREEDHAR, B;SAI PRASAD, PS;RAO,

P KANTA;RAO, KS RAMA;BERRY, FJ;SMART, LE Effect of

tungsten addition to Pd/ZrO2 system in the

hydrodechlorination activity of CCl2F

2


223(1-2) : 347-351


185

NARAYANA, KV;RAJU, B DAVID;KHAJA MASTHAN, S;RAO,

V VENKAT;RAO, P KANTA;SUBRAHMANIAN, R;MARTIN, A;

ESR spectroscopic characterization of V2O5/AlF

3

ammoxidation catalyts


NARAYANA, KV;RAJU, B DAVID;KHAJA MASTHAN, S;RAO,

V VENKAT;RAO, P KANTA; MARTIN, A; Cerium fluoride

supported V2O

5 catalysts: physico-chemical

characterization and 3-picoline ammoxidation activity


223(1-2) : 321-328

NARENDAR, M;REDDY, M SOMI;RAO, K RAMA; A mild and

efficient oxidative deprotection of THP ethers with NBS

in the presence of b-cyclodextrin in water


NARENDER, M;SURENDRA, K;KRISHNAVENI, NS;REDDY, M

SOMI;RAO, K. RAMA; A facile regioselective ring opening

of aziridines to haloamines using tetrabutylammonium

halides in the presence of â-cyclodextrin in water


NARENDER, N;KRISHNA MOHAN, KVV;SRINIVASU,

P;KULKARNI, SJ;RAGHAVAN, KV; A simple, efficient and

regioselective oxychlorination of aromatic compounds

using ammonium chloride and oxone

Indian Journal of Chemistry Section B (2004) 43 (6) :

1335-1338

NARENDAR, P;GANGADASU, B;RAMESH, C;RAJU B

CHINNA;RAO, VJ; Facile and selective synthesis of

chloromethylpyridines and chloropyridines using

diphosgene/triphosgene


NISHA, CK; MANORAMA, SV; GANGULI, M; MAITI, SOUVIK;

KIZHAKKEDATHU, JAYACHANDRAN N ; Complexes of

poly(ethylene glycol)-based cationic random copoly

mer and calf thymus DNA: A complete biophysical

characterization

Langmuir (2004) 20(6) : 2386-2396

NISHA, CK;MANORAMA, SV;KIZHAKKEDATHU, JAYACHANDRAN N; MAITI, SOUVIK; Water-Soluble Complexesfrom Random Copolymer and Oppositely ChargedSurfactant. 2. Complexes of Poly(ethylene glycol)-basedcationic random Copolymer and Bile SaltsLangmuir: (2004) 20(20) : 8468-8475

NISHA, CK; MANORAMA, SV; MAITI, S; JAYACHANDRAN,KN; ASWAL, VK; GOYAL, PS; Small-angle neutronscattering studies on water soluble complexes of poly(ethylene glycol)-based cationic random copolymerand SDS - PramanaJournal of Physics (2004) 63(2) : 315-320

NIVASU, M VENKATA;REDDY, THIMMA T;TAMMISHETTI, S;In situ polymerizable polyethyleneglycol containingpolyesterpolyol acrylates for tissue sealant applicantsBiomaterials (2004) 25(16) : 3283-3291

NIVASU, M VENKATA;REDDY, THIMMA T;TAMMISHETTI, S;In situ polymerizable polyester polyols for tissue sealantapplications : Effect of choice of acid and diol on sealantproperties Trends in Biomaterials and Artificial Organs (2004)18(1) : 52-59

NIVASU, M VENKATA;YARAPATHI, V REDDY;TAMMISHETTI,S; Synthesis, UV photo-polymerization and degradationstudy of PEG containing polyester polyol acrylatesPolymers for Advanced Technologies (2004) 15(3)128-133

NOORJAHAN, M;DURGA KUMARI, V;SUBRAHMANYAM,M;BOULE, P ; A novel and efficient photocatalyst: TiO2-HZSM-5 combinate thin filmApplied Catalysis B: Environmental (2004) 47(3) :209-213

PADMASRI, AH;VENUGOPAL, A;KUMAR, V SIVA;SHASHIKALA, V;NAGARAJA, BM; SEETHARAMULU, P;SREEDHAR, B;RAJU, B DAVID;RAO, P KANTA;RAO, KSRAMA; Role of hydrotalcite precursors as supports forPd catalysts in hydrodechlorination of CCl

2F

2


223(1-2) : 329-337

Publications

186

PRASAD, TEV;ASWIN RAJ, ED;MAHENDER, G;REDDY, MSAINATH;KUMAR, V SENHIL;SATISH GARAPATI;PANTANJALI, V;PRASAD, DHL; Bubble temperatureMeasurements on some Binary Mixtures formed bytetrahydrofuran or Amylalcohol with Hydrocarbons orChlorohydrocarbons or Butanols at 94.6 or 05.8 kPaJournal of Chemical and Engineering Data (2004) 49(4) : 746-749

PRASAD, TEV;BANERJEE, S;KISHORE BABU, J;PRASAD,DHL; Boiling temperature measurements on the binarymixtures formed by dimethyl carbonate with somechloroethanes and chloroethylenes at 95.8 kPa FluidPhase Equilibria (2004) 218(2) : 291-293

PRASAD, TEV;HARITHA, M;GEETHA, NB;PAVAN KUMAR,YP;PRASAD, DHL; Bubble Temperature Measurementson the Binary Mixtures of Chlorobenzene with Methanol,n-propanol and sec-Butanol at 94.6 kPaPhysics and Chemistry of Liquids (2004) 42(4) : 385-389

PRASAD, TEV; KUMAR, SS; GOUD, MBP; KUMAR, PA;SRINIVAS, A; REDDY, PS; PRASAD, DHL; Erratum: Bubbletemperature measurements on binary mixtures formedby cyclohexane at 94.7 kPa (Journal of Chemical andEngineering Data (2003) 48 (351-353))Journal of Chemical and Engineering Data (2004) 49(3): 740

PRASAD, TEV; PATANJALI, V; SUDHAKAR, TA; RADHIKA,BS;ARVIND, VM;PRASA, DHL; Bubble temperaturemeasurements on the binary mixtures of n-heptane ornitrobenzene or chlorobenzene with somechloroethanes and chloroethylenes at (94.6 to 95.8) kPaJournal of Chemical and Engineering Data (2004) 49(2): 199-201

PRASAD, TEV;PRASAD, DHL;KALPANA, T; Bubbletemperatures of the binary mixtures of 1,2-dimethylbenzene with 2-propanol, 1-butanol, 2-propanol, 1-butanol, 2-methylpropane-1-ol and 2methypropane-2-ol at 95K PaChemical Engineering Communications (2004)

191(1) : 17-26

PALANIAPPAN, S; Benzoyl peroxide oxidation route topolyaniline salts – Part IPolymers for Advanced Technologies (2004) 15(3)111-117

PALANIAPPAN, SRINIVASAN;CHANDRA SHEKAR,RAMPALLY; Synthesis of 7-hydroxy-4-methyl coumarinusing polyaniline supported acid catalystJournal of Molecular Catalysis A: Chemical (2004)209(1-2) : 117-124

PALANIAPPAN, SRINIVASAN;CHANDRA SHEKAR,RAMPALLY; Transesterification of ketoesters withalcohols using polyaniline salts as catalystsPolymers for Advanced Technologies (2004) 15(3) :140-143

PALANIAPPAN, SRINIVASAN; JOHN, AMALRAJ; AMARNATH, CHELLACHAMY ANBALAGAN;RAO, V JAYATHIRTHA; Mannich-type reaction in solvent freecondition using reusable polyaniline catalystJournal of Molecular Catalysis A: Chemical (2004)218(1) : 47-53

PALANIAPPAN, SRINIVASAN;SARAVARAN, C;AMARNATH,CHELLACHAMY ANBALAGAN;RAO, V JAYATHIRTHA;Polyaniline salts and complexes as catalyst in bisindolesynthesisCatalysis Letters (2004) 97(1-2) : 77-81

PALANIAKUMAR, M;VAIRAMANI, M;PRASADA RAJU,N;LOBO, CHARMAINE; ANBUMANI, N;GIRISH KUMAR,CP;MENON, THANGAM;SHANMUGASUNDARAM, S; Rapiddiscrimination between strains of beta haemolyticstreptococci by Cell mass spectrometryIndian Journal Medical Research (2004) 119(6) : 283-288

PANDA, SIVA SANKAR;CHATTOPADHYAY;RAJU, KVSN;Roof cooling materials and coatings: An EmergingTechnologyPaintindia (2004) : 65-74

PRABHAKAR, S; RADHA KISHAN, M; MIRZA, SP; RAGHAVAN, KV; VAIRAMANI, M; Mass spectral study of meso-alkyl and meso-cycloalkyl calix(4) pyrroles under lectronimpact conditionsRapid Communications in Mass Spectrometry (2004)18(18) : 2077-2086


187

PRASAD, TEV;PRASAD, DHL;KISHORE BABU, J;BANERGEE,

S; Bubble Temperature Measurements on the Binary

mixtures formed by 1,2-Dimethyl-benzene with some

Chloroethanes and Chloroethylenes at 95.8 kPa

Chemical Engineering Communications (2004)

191(10) : 1323-1328

PRASAD, TEV;PRASAD, DHL;NAVEEN, PG;KUMAR, B

SANTOSH; Bubble temperature measurements on the

binary mixtures of 1,4-Dimethyl-benzene with iso-,sec-

and tert-Buranols at 95 kPa:

Chemical Engineering Communications (2004) 191(7)

: 998-1002

PRASAD, TEV;RAVI PRASHANTH, P;KUMAR, D

SURESH;PRASAD, DHL; Bubble temperature

measurements on the binary mixtures of Dimethyl

carbonate with some Alcohols at 95.8 kPa

Journal of Chemical and Engineering Data (2004)

49(4) : 744-745

PREMSINGH, S;VENKATARAMANAN, NS;RAJAGOPAL,

S;MIRZA, SP;VAIRAMANI, M; Electron Transfer reaction

of Oxo(salen)chromium(V) ion with anilines

Inorganic Chemistry (2004) 43(18) : 5744-5753

PRIYAKUMAR, UD;PUNNAGAI, M;KRISHNA MOHAN,

GP;SASTRY, G NARAHARI; A computational study of

cation-interactions in polycyclic systems: exploring the

dependence on the curvature and electronic factors

Tetrahedron (2004) 60(13) : 3037-3043

PRIYAKUMAR, UD;REDDY, AS;SASTRY, G NARAHARI; The

design of molecules containing planar tetracoordinate

carbon


PRIYAKUMAR, UD;SASTRY, G NARAHARI; Design of

neutral hydrocarbons having a planar tetracoordinate

carbon

Indian Journal of Chemistry Section A-Inorganic Bio-

Inorganic Physical Theoretical & Analytical Chemistry

(2004) 43(3) : 455-457

PRIYAKUMAR, UD;SASTRY, G NARAHARI; A system with

three contiguous planar tetracoordinate carbons is

viable: a computational study on a C6H62=isomer


PRIYAKUMAR, UD;PUNNAGAI, M;SASTRY, G NARAHARI;

Facile valence isomerization among bis(silacyclo

propenyl), disila(Dewar benzene) and disilabenzvalene

Journal of Organometallic Chemistry (2004) 689(7) :

1284-1287

PRIYAKUMAR, UD;SASTRY, G NARAHARI; C21H9Z (Z=-3

to +3): a theoretical study on the redox behaviour of C3

symmetric fragment of C60

Journal of Molecular Structure: THEOCHEM (2004)

674(1-3) : 69-75

PRIYAKUMAR, UD;SASTRY, G NARAHARI;MEHTA,

GOVERDHAN; Development of predictive models of -

facial selectivity; a critical study of nucleophilic Addition

to sterically unbiased ketones

Tetrahedron (2004) 60(15) : 3465-3472

PUNNAGAI, M;DINADAYALANE, TC;SASTRN, G

NARAHARI; Density functional theory study of the Diels-

Alder reactivities of [b]-annelated cyclic five-membered

dienes

Journal of Physical Organic Chemistry (2004) 17(2) :

152-161

PUNNAGAI, M;JOSEPH, S;SASTRY, GN; A theoretical study

of porphyrin isomers and their core-modified analogues:

Cis-trans isomerism, tautomerism and relative

stabilities

Journal of Chemical Sciences (2004) 116(5) : 271-283

PUNNAGAI, M;SASTRY, G NARAHARI; Theoretical study

on the structure and stability of ring inverted porphyrin

isomers

Journal of Molecular Structure THEOCHEM (2004)

684(1-3) : 21-28

Publications

188

RADHA KRISHNA, P;KRISHNA RAO, LOPINTI;KANNAN,

V; Diastereoselective Baylis–Hillman reaction: first use

of chiral 2,3-epoxy aldehydes as novel electrophiles


RADHAKRISHNA, PALAKODETY; NARSINGAM,M;

KANNAN, V; Use of a Baylis–Hillman adduct in the

stereoselective synthesis of syributins via a RCM

protocol


RADHA KRISHNA, PALAKODETY;SEKHAR, ER;KANNAN, V;

N-methylmorpholine and urotropine as useful base

catalysts in Baylis-Hillman reaction


RADHA KRISHNA, P;GOVARDHAN REDDY, Ch;SHARMA,

GVM; Yb(Otf )3 and ZrCl4 mediated rearrangement of

alkoxybenzyl allyl ethers into aldehydes

Letters in Organic Chemistry (2004) 1(3) : 212-214

RADHA KRISHNA, P; RACHNA, SACHWANI; KANNAN,

V; ‘Double asymmetric induction’ as a novel tool for high

stereocontrol in Baylis-Hillman reaction

Chemical Communications (Cambridge, England)

(2004) (22) : 2580-2581

RADHA KRISHNA, P;RAMANA REDDY, VV;SHARMA, GVM;

Flexible and simple route for the stereoselective

synthesis of trisubstituted g-butyrolactones: Total

synthesis of (+)-Blastomycinone and its analogs

Synthesis-Stuttgart (2004) (13): 2107-2114

RAGHAVAN, SADAGOPAN;KUMAR, Ch NAVEEN;TONY,

KA;REDDY, S RAMAKRISHNA;RAVI KUMAR, K; Regio-and

stereoselective transfer of p-toluenesulfonamido group

from sulphur to carbon: preparation of aminoalcohol

derivatives from allylalcohols

Tetrahedron Letters, (2004) 45(39) : 7231-7234

RAGHAVAN, SADAGOPAN;RAJENDER, A; Stereoselective

synthesis of (-)-allosedamine


RACHEL, A;DURGA KUMARI, V;SUBRAMANIAN, R;CHARY,

KVR;RAO, PK ; A study of the structural-characterization

and cyclohexanol dehydrogenation activity of CU/

GAMMA-AL20

3 catalysts -

Indian Journal of Chemistry Section A Inorganic

Bioinorganic Physical Theoretical and Analytical

Chemistry (2004) 43(6) : 1172-1180

RADHAKRISHNA, M;RAO, C KAMESWARA; Axial vibration

of U-shaped bellows with elastically restrained end

conditions

Thin Walled Structures (2004) 42(3) : 415-426

RADHA KISHAN, M;RADHA RANI, V;MURTY, MRVS;SITA

DEVI, P;KULKARNI, SJ;RAGHAVAN, KV; Synthesis of

calixpyrroles and porphyrins over molecular sieve

catalysts


223(1-2) : 263-267

RADHAKRISHNA, PALAKODETY;KANNAN, V;REDDY, PVN;

N-methylprolinol catalysed asymmetric Baylis-Hillman

reaction

Advanced Synthesis and Catalysis (2004) 346(6) : 603-606

RADHAKRISHNA, PALAKODETY;KANNAN, V;SHARMA,

GVM; FeCl3 and Yb(Otf ) (3) mediated conversion of

acetates of the Baylis-Hillman adducts into (Z) and (E)

trisubstituted alkenes


RADHAKRISHNA, PALAKODETY;MANJUVANI, A;KANNAN,

V;SHARMA, GVM; Sulpholane-A new solvent for the

Baylis-Hillman reaction


RADHAKRISHNA, PALAKODETY;KANNAN, V;SHARMA,

GVM; First Diastereoselective Intramolecular Baylis-

Hillman Reaction: An Easy Access to Chiral alpha-

Methylene-beta-hydroxylactones


6467-6469


189

RAGHAVAN, SADAGOPAN;RAJENDER, A; JOSEPH, SUJU

C;RASHEED, M ABDUL;KUMAR, K RAVI; Regio-and

stereoselective synthesis of 1,3-aminoalcohol

derivatives from allylamine derivatives via internal

sulfinyl group participation


RAGHAVAN, SADAGOPAN;RASHEED, M ABDUL; Modular

and stereoselective formal synthesis of MeBmt, an

unusual amino acid constituent of cyclosporin-A

Tetrahedron (2004) 60(13) : 3059-3065

RAGHAVAN, SADAGOPAN;REDDY, S RAMAKRISHNA;

Stereoselective synthesis of the enantiomer of the key

fragment of crocacin


RAGHAVAN, SADAGOPAN;SREEKANTH, T; Novel and

stereoselective synthesis of (+)-lentiginosine


RAGHAVAN, SADAGOPAN;TONY, KA; Stereoselective

synthesis of (2R,3R) and 2R,3S)-3-hydroxyleucines


RAGHAVAN, SADAGOPAN;RAJENDER, A ; Stereoselective

synthesis of (“)-allosedamine and (1R,3R)-HPA-12 from

-p-toluenesulfonamido-,-unsaturated sulfoxide

Tetrahedron (2004) 60(23) : 5059-5067

RAGHLUKUMAR, C;RAGHUKUMAR, S;SHEELU, G;GUPTA,

SM;NATH, BN;RAO, BR; Buried in time-culturable fungi

in a deep-sea sediment core from the chagos trench,

Indian Ocean Deep-Sea Research Part – I

Oceanographic Research Papers (2004) 51(11) :

1759-1768

RAGHUNATH, P; BHANUPRAKASH, K; SRINIVAS,

R; Formation of Silicon analogues of thio-isocyanic acid,

HNSiS, and its isomers by Neutral-Neutral reactions of

the fragments: A computational study

Journal of Physical Chemistry – A (2004) 108(42) :

9218-9225

RAHMAN, MF;MAHBOOB;GROVER, P; In-Vitro

acetylcholinesterase inhibition by novel of compounds

in various tissues of the fish Channa-punctatus

Bulletin of Environmental Contamination and

Toxicology (2004) 72(1) : 38-44

RAHMAN, MF;MAHBOOB, M;GROVER, P; Comparative sensitivities

of in vitro acetylcholinesterase inhibition by novel

organophosphorus compounds in broiler chicken

Toxicol. International (2004) 11(1) : 49-53

RAHMAN, MF;SIDDIQUI, MKJ; Biochemical effects of

vepacide (from Azadirachta indica) on Wistar rats during

subchronic exposure

Ecotoxicology And Environmental Safety (2004)

59(3) : 332-339

RAJU, B DAVID; RAO, KS RAMA;SALVAPATHI, GS;PRASAD,

PS SAI; RAO, P KANTA; Role of Support and Promoter in

the Selective Conversion of Isophorone to 3,5-Xylenol

over Chromia Catalysts

Topics in Catalysis (2004) 29(3-4) : 167-174

RAJU, B CHINA;NEELAKANTAN, PARVATHI;BHALERAO,

UT ; Quinone methide initiated cyclization reaction:

synthesis of 4-aryl-1,2,3,4-tetrahydrooisoquinolines

Tetrahedron Letters (2004) 45(40) :7487-7489

RAJU, B CHINA;NEELAKANTAN, PARVATHI;BHALERAO,

UT; A facile and convenient method for the synthesis of

nitro phenols and chloropyridinols


RAM, MS;PALANIAPPAN, S; A process for the preparation

of polyaniline salt doped with acid and surfactant groups

using benzoyl peroxide

Journal of Materials Science (2004) 39(9) : 3069-3077

RAMARAO, VVVNS;REDDY, G VENKAT;MAITRAIE, D;

RAVIKANTH, S;YADLA, R;NARSAIAH, B;RAO, P SHANTHAN

One-pot synthesis of fluorine containing 3-cyano/

ethoxycarbonyl-2-methyl-benzo[b]furans

Tetrahedron (2004) 60(52) : 12231-12237

Publications

190

RANI, GN;AYACHIT, NH;NATH, KR; RAO, VJ; Preparation

and characterization of Eu3+ doped powder spinel

phosphors (MgAl1.8Y0.2-xO4)

Spectrochimica Acta - Part A: Molecular and

Biomolecular Spectroscopy (2004) 60(11) :

RANI, K YAMUNA;PATWARDHAN, SC; Data-driven

modeling and optimization of semi-batch reactors

using “Artificial Neural Networks” -

Industrial and Engineering Chemistry Research (2004)43(23) : 7539-7551

RAO, A GANGAGNI;NAIDU, G VENKATA; PRASAD,K KRISHNA;

RAO, N CHANDRASEKHAR; MOHAN, S VENKATA; JETTY,

ANNAPURNA; SARMA, PN; Anaerobic treatment of

wastewater with high suspended solids from a bulk drug

industry using fixed film reactor (AFFR)

Bioresource Technology (2004) 93(3) : 241-247

RAO, DS;PRASAD, DHL; Activity coefficients for the binary

mixtures of methyl-ethylketone with some chlorohydro

carbons at 94.8 kPa

Physics and Chemistry of Liquids (2004) 42(6) : 585-588

RAO, I NAGESHWAR;BORUAH, A;KUMAR, SK;KUNWAR,

AC;DEVI, AS;VYAS, K; RAVIKUMAR, K;IQBAL, J; Synthesis

and conformational studies of novel cyclic peptides

constrained into a 3(10) helical structure by a

heterochiral D-pro-L-pro dipeptide template

The Journal of Organic Chemistry (2004) 69(6) : 2181-

2184

RAO, J VENKATESWARA; Effects of monocrotophos and

its analogs in acetylcholinesterase activity’s inhibition

and its pattern of recovery on euryhaline fish,

Oreochromis mossambicus

Ecotoxicology and Environmental Safety (2004) 59(2)

: 217-222

RAO, J VENKATESWARA; KAVITHA, P; Toxicity of azodrin

on the morphology and acetylcholinesterase acitivity

of the earthworm Eisenia foetida

Environmental Research (2004) 96(3) : 323-327

RAMU, R;RAVINDRANATH, N;REDDY, MR; DAS, B; Studieson novel synthetic methodologies. Part 31. Silica-supported sodium hydrogen sulfate-catalyzed faciletransformation of p-hydroxybenzyl alcohols to p-hydroxybenzyl ethers and thioethersSynthetic Communications (2004) 34(17) : 3135-3145

RAMU, SRIDARALA;LINGAIAH, N;PRABHAVATHI DEVI,LBN;PRASAD, RBN; SURYANARAYANA, I;SAI PRASAD, PS;Esterification of palmitic acid with methanol overtungsten oxide supported on zirconia solid acidcatalysts: effect of method of preparation of the catalyston its structural stability and reactivityApplied Catalysis A: General (2004) 276(1-2) : 163-168

RANGANATHAN, S;MURALEEDHARAN, KM;VAISH,NARENDRA K; JAYARAMAN, NARAYANASWAMY; Halo-and selenolactonisation: the two major strategies forcyclofunctionalisationTetrahedron (2004) 60(25) : 5273-5308

RANGANATHAN, S;RAO, Ch C;VUDAYAGIRI, YBRD;RAJESH;JAGADEESH; Solubilization of silica: Synthesis,characterization and study of penta-coordinatedpyridine N-oxide silicon complexesJournal of Chemical Sciences (2004) 116(3) : 169-174

RANGANATHAN, S;CHERUKU, PRADEEP; MADHU SUDANAN,KP;GEORGE, KS; One-step transformation of 2-oxa-3-azabicyclo[2.2.1]hept-5-ene and methyl 2,3-diazabicyclo[2.2.1]heptane-2-carboxylate to ion uptake systemsARKIVOC (Gainesville, FL, United States) (2004) (8) :28-36

RANI, AS; JETTY, A;RAMAKRISHNA, SV; Kinetic studies ofpenicillin production during batch and repeated batchin fluidized bed bioreactor with agar immobilized P.chrysogenum cellsIndian Journal of Biotechnology (2004) 3(3) : 394-399

RANI, AS;SATYAKALA, M;MURTY, US; Stevia rebaudiana,bio-sweetener of the future: A reviewAsian Journal of Microbiology, Biotechnology and

Environmental Sciences (2004) 6(3) : 453-460


191

RAO, J VENKATESWARA;PALLELA, R;JAKKA, NM;USMAN,

PK; Susceptibility of Culex quinquefasciatus larvae to the

larvicide, Fenthion (Baytex®) at Hyderabad City, India

Pestology (2004) 28(12) : 19-22

RAO, J VENKATESWARA;SRIKANTH, K;CHAKRA REDDY,

N;SRIDHAR, V; Effect of imidacloprid on locomotor

behaviour and acetylcholinesterase activity of

subterranean termites, Odontotermes obesus

Pestology (2004) 28(9) : 13-18

RAO, K RAJESWAR;RAO, S VENKATESWAR;CHARY, V;

Estimation of risk indices of chemicals during

transportation

Process Safety Progress (2004) 23(2) : 149-154

RAO, KVS;SUBRAHMANYAM, M;BOULE, P; Immobilized

TiO2 photocatalyst during long-term use: decrease of

its activity

Applied Catalysis B: Environmental (2004) 49 (4) : 239-249

RAO, M MOHAN;JAYALAKSHMI, M; REDDY, R

SUDARSHAN; Time-selective hydrothermal synthesis of

SnS nanorods and nanoparticles by thiourea hydrolysis


RAO, R NAGESWARA;ALVI, SN; HPLC studies on evaluation of purity

of pesticide reference standard materials

Journal of Metrological Society of India (2004) 19 :121-126

RAO, R NAGESWARA;NAGARAJU, V; Separation and determination

of synthetic impurities of norfloxacin by reversed-phase high

performance liquid chromato graphy

Journal of Pharmaceutical and Biomedical Analysis

(2004) 34(5) : 1049-1056

RAO, R NAGESWARA; NAGARAJU, V; Separation and

determination of synthetic impurities of difloxacin by

reversed-phase high-performance liquid chromato

graphy

Journal of Pharmaceutical and Biomedical Analysis

(2004) 36(4) : 729-735

RAO, R NAGESWARA;PARIMALA, P;KHALID, S;ALVI, SN;Detection of the adulteration of traditional alcoholicbeverages by the separation and determination ofalprazolam, chloralhydrate and diazepam usingreversed-phase high-performance liquid chromatographyAnalytical Sciences: The International Journal Of TheJapan Society For Analytical Chemistry , (2004) 20(2): 383-386

RAO, R NAGESWARA;NAGARAJU, D;ALVI, SN;BHIRUD, SB;Development and validation of a liquid chromatographic method for determination of related-substances of mosapride citrate in bulk drugs andpharmaceuticalsJournal Of pharmaceutical And Biomedical Analysis(2004) 36(4) : 759-767

RAO, R NAGESWARA;SHANKARAIAH, B;SUNDER, MS;Separation and determination of diastereomers of l-cyhalothrin by normal phase-liquid chromatographyusing a CN columnAnalytical Sciences (2004) 20(12) : 1745-1748

RAO, R SREENIVAS;PRAKASHAM, RS;KRISHNA PRASAD,K;RAJESHAM, S; SARMA, PN;RAO, L VENKATESWAR; Xylitolproduction by Candida sp.: parameter optimizationusing Taguchi approachProcess Biochemistry (2004) 39(8) : 951-956

RATNAMALA, A; DURGAKUMARI, V;SUBRAHMANYAM, M;ARCHANA, N; CeZSM-5-a designer’s catalyst for selectivesynthesis of octahydroacridineChemical Communications (Cambridge, England)(2004) (23) : 2710-2711

RATNAMALA, A;SUBRAHMANYAM, M;DURGA KUMARI,V; Highly selective and single step vapor phase synthesisof 2,6-bis(4-methylphenyl)pyridine over Al-MCM-41molecular sievesApplied Catalysis A: General (2004) 264(2) : 219-224

RAVIKANTH, S;REDDY, G VENKAT;MAITRAIE, D;RAMA RAO,VVVNS;RAO, P SHANTHAN;NARSAIAH, B Synthesis ofnovel 5-Trifluoromethyl-2,4,7-trisub stituted pyrido[2,3-d] pyrimidinesSynthetic Communications (2004) : 34(24) : 4463-4469

Publications

192

RAVIKUMAR, K;SELVANAYAGAM, S;GOUD, TV;

KRISHNAIAH, P;VENKATESWARLU, Y A furodysinin

lactone derivative from the marine sponge dysidea

fragilis

Acta Crystallographica Section E (Str. Reports Online)

(2004) 60(Part 1) : 0139-0141

RAVIKUMAR, K;MAHESH, M;NARAYANA REDDY, VV; Imino

Diels-Alder adducts. I. Two furo[3,2-c]quinoline

diastereoisomers

Acta Crystallographica. Section C, Crystal Structure

Communications (2004) 60(12) : o887-o889

RAVINDER, K;REDDY, AV;KRISHNAIAH, P; VENKATA

RAMANA, G;REDDY, VLN; VENKATESWARLU, Y; Can

catalyzed one-pot synthesis of á-amino phosphonates

from carbonyl compounds


RAVINDRANATH, NASI;REDDY, M RAVINDER;RAMESH,

CHIMMANI; RAMU, RAVIRALA;PRABHAKAR, ANA

BATHULA; JAGADEESH, BHARATAM;DAS, B; New

Lathyrane and Podocarpane Diterpenoids from

Jatropha curcas


608-611

RAVINDRANATH, N;REDDY, M RAVINDER;RAMESH, C;DAS,

B; Deoxypressmerins from Jatropha curcas: Are they also

plant metabolites?

Phytochemistry (2004) 65(16) : 2387-2390

REDDY, BM;GANESH, IBRAM;KHAN; ATAULLAH ;

Stabilization of nanosized titania-anatase for high

temperature catalytic applications


223(1-2) : 295-304

REDDY, BM;LAKSHMANAN, PANDIAN;KHAN, ATAULLAH;

Investigation of surface structures of dispersed V2O

5 on

CeO2-SiO

2, CeO

2-TiO

2, and CeO

2-ZrO

2 mixed oxides by

XRD, Raman, and XPS techniques

Journal of Physical Chemistry B (2004) 108(43) :

16855-16863

REDDY, BM;SREEKANTH, PM;KHAN, A; Facile synthesis of

1,1-diacetates from aldehydes using environmentally

benign solid acid catalyst under solvent-free conditions


REDDY, B RAMACHANDRA;KUMAR, J RAJESH;RAJA, K

PHANI;REDDY, A VARADA; Solvent extraction of Hf(IV)

from acidic chloride solutions using cyanex 302

Minerals Engineering (2004) 17(7-8) : 939-942

REDDY, B RAMACHANDRA;KUMAR, J RAJESH;REDDY, A

VARADA; Liquid-liquid extraction of tetravalent

zirconium from acidic chloride solutions using cyanex

272

Analytical Sciences The International Journal Of The

Japan Society For Analytical Chemistry (2004) 20(3)

: 501-505


VARADA; Solvent extraction of zirconium(IV) from acid

chloride solutions using LIX 84-IC

Hydrometallurgy (2004) 74(1-2) : 173-177


VARADA; Solvent extraction of zirconium(IV) from acidic

chloride solutions using the thiosubstituted

organophosphorus acids Cyanex 301 and 302

Journal of Chemical Technology and Biotechnology

(2004) 79(11) : 1301-1307


VARADA;NEELA PRIYA, D; Solvent extraction of

zirconium(IV) from acidic chloride solutions using 2-ethyl

hexyl phosphonic acid mono-2-ethyl hexyl ester (PC-

88A)


REDDY, B RAMACHANDRA;RADHIKA, P;KUMAR, J

RAJESH;NEELA PRIYA, D; RAJGOPAL, K; Extractive

spectrophotometric determination of cobalt (II) in

synthetic and pharmaceutical samples using Cyanex

923



193


VARADA; Solvent extraction of tetravalent hafnium

from acidic chloride solutions using 2-ethyl hexyl

phosphonic acid mono-2-ethyl hexyl ester (PC-88A)

Minerals Engineering (2004) 17(4) : 553-556

REDDY, B RAMACHANDRA;NEELA PRIYA, D; Solvent

extraction of Ni(II) from sulfate solutions with LIX 841:

Flow-sheet for the separation of Cu(II), Ni(II) and Zn(II)


REDDY, B RAMACHANDRA;NEELA PRIYA, D;KUMAR, J

RAJESH; Solvent extraction of cadmium (II) from

sulphate solutions using TOPS 99,PC 88A, Cyanex 272

and their mixtures


REDDY, K MADHUSUDAN;SATYANARAYANA, SUNKARA,

V MANORAMA;MISRA, RDK; A Comparative study of the

gas sensing behavior of nanostructured nickel ferrite

synthesized by hydrothermal and reversemicelle

techniques

Material Research Bulletin (2004) 39(10) : 1491-1498

REDDY, K MADHUSUDAN;GUIN, DEBANJAN;SUNKARA, V

MANORAMA; Selective synthesis of nanosized TiO2 by

hydrothermal route: Characterization, structure

property relation, and photochemical application

Journal of Materials Research (2004) 19(9) : 2567-

2575

REDDY, M NARENDER;REHANA, TASNEEM; RAMA

KRISHNA, S;CHOWDHARY, KPR;DIWAN, PV; Beta-

cyclodextrin complexes of celecoxib: molecular-

modeling, characterization and dissolution studies

AAPS PharmSci [Electronic Resource] (2004) 6(1) : E7

REDDY, M PRATAP;SRINIVAS, B;DURGA KUMARI,

V;SUBRAHMANYAM, M;SHARMA, PN; An integrated

approach of solar photocatalytic and biological

treatment of N-containing organic compounds in

wastewater

Toxicological and Environmental Chemistry (2004)

86(1-4) : 125-138

REDDY, M SOMI;NARENDER, M;RAO, K RAMA;

Regeneration of carbonyl compounds by oxidativecleavage of oximes with NBS in the presence of b-cyclodextrin in waterSynthetic Communications (2004) 34(21) : 3875-3881

REDDY, P NAGI;SRIKANTH, R;BHANUPRAKASH, K;SRINIVAS, R; Generation and characterization of ionicand neutral methylene isothiocyanate by a combinestandem mass spectrometry and computational studyRapid Communications In Mass Spectrometry (2004)18(17) : 1939-1946

REDDY, P NAGI;SRIKANTH, R;SWAMY, NS; BHANUPRAKASH, K;SRINIVAS, R; Generation andcharacterization of ionic and neutral selenocumuleneHC3Se+/. by tandem mass spectrometry andcomputational studyInternational Journal of Mass Spectrometry (2004)232(3) : 231-237

REDDY, SKVN;PRASAD, DHL;KRISHNAIAH, ABBURI; Vapor-Liquid Equilibria for the Binary Systems ofdimethoxymethane with some fuel oxygenates -Journal of Chemical and Engineering Data 49(6) :1546-1549

REDDY, S VENKAT;PULLELA, V;SRINIVAS, B;PRAVEEN,K;HARA KISHORE, B;CHINA RAJU; MURTHY, USURYANARAYANA; RAO,J MADHUSUDANA;Antibacterial constituents from the berries of PipernigrumPhytomedicine (2004) 11(7-8) : 697-700

REDDY, T JAGADESHWAR;PRABHAKAR, S;VIJAYASARADHI, UVR;RAO, VJ; VAIRAMANI, M; Mass spectralstudy on O,O-dialkyl N,N-dialkyl phosphoramidatesunder electron impact conditionsJournal Of The American Society For MassSpectrometry (2004) 15(4) : 547-557

REDDY, T JAGADESHWAR;VIJAYA SARADHI, UVR;PRABHAKAR, S;VAIRAMANI, M; Trace level detection andidentification of chemicals related to the chemicalweapons convention from complex organic samples -Journal of Chromatography A (2004) 1038(1-2) : 225-230

Publications

194

REDDY, T THIMMA; TAMMISHETTI, SHEKHARAM Freeradical degradation of guar gumPolymer Degradation and Stability (2004) 86(3) : 455-459

REDDY, V YARAPATHY;SAMBASIVUDU, K;TAMMISHETTI,SHEKHARAM; Synthesis of dihydropyrimidinones usingreusable poly(4-vinyl pyridine co divinylbenzene)Cu(II)complexCatalysis Communications (2004) 5(9) 511-513

REDDY, V YARAPATHY ; Novel angular furanocoumarins:Synthesis of 8-aroyl-9-styryl furobenzopyran-2-onesHeterocyclic Communications (2004) 10(1) : 59-62

SABITHA, G;REDDY, EV;SWAPNA, R;REDDY, NM;YADAV, JS;Bismuth(III) chloride catalyzed efficient and selectivecleavage of trityl ethersSynlett (2004) (7) : 1276-1278

SABITHA, G;REDDY, GSKK;REDDY, KB;YADAV, JS; Iodotrimethylsilane-mediated cross-aldol condensation: Afacile synthesis of alpha, alpha -bis (substitutedbenzylidene) cycloalkanonesSynthesis-Stuttgart (2004) (2) : 263-266

SABITHA, G;VENKATA REDDY, E;FATIMA, N;YADAV,JS;RAMA KRISHNA, KVS; KUNWAR, AC;Diastereoselective synthesis of chiral cis-annulatedpolycyclic heterocycles from D-glucose by dominoKnoevenagel-hetero-Diels Alder reactionsSynthesis-Stuttgart (2004) (8) : 1150-1154

SABITHA, G;KIRAN KUMAR, GS;REDDY, K BHASKAR;REDDY, N MALLIKARJUNA;YADAV, JS; A new, efficient andenvironmentally bening protocol for the synthesis of1,5-benzodiazepines using cerium (III) chloride/sodiumiodide supported on silica gelAdvanced Synthesis and Catalysis (2004) 346(8) : 921-923

SALEHA BANU, B;ISHAQ, MOHD;DANADEVI, K;PADMAVATHI, P;AHUJA, YR; DNA damage in leukocytes of micetreated with copper sulfateFood And Chemical Toxicology: (2004) 42(12) : 1931-1936

SASTRY, GSR;RAVI PRASAD, P; Determination of alcoholinpetrol-alcohol mixturesIndian Journal of Chemical Technology (2004) 11(5) :323-325

SATYA KUMAR, DVR;KRISHNA, D;MURTY, US;SAI, KSK -Impact of different housing structures on filarialtransmission in rural areas of southern IndiaSoutheast Asian Journal of Tropical Medicine andPublic Health (2004) 35(3) : 587-590

SHAILAJA, M;MANJULA, A;RAO, BV;PARVATHI, N; Simpleprotocol for the synthesis of 3,4-dihydropyrimidin-2(1H)-ones using SnCl2·2H2O-LiCl as an inexpensivecatalyst systemSynthetic Communications (2004) 34 (9) : 1559-1564

SEKAR, R;AZHAGUVEL, S; Indirect photometric assaydetermination of gabapentin in bulk drug and capsulesby capillary electrophoresisJournal of Pharmaceutical and Biomedical Analysis(2004) 36(3) : 663-667

SESHADRI, PR;SELVANAYAGAM, S;VELMURUGAN,D;RAVIKUMAR, K;SURESH BABU, AR;RAGHUNATH, R; 4’-(3-chlorophenyl)-1-METHYL-1H-indole-3-spiro-2’-pyrrolidine-3’-spiro-2’’-indan-2,1’’,3’’-trioneActa Crystallographica Section E (Structure ReportsOnline) (2004) 60(Part 1) : 051-053

SESHADRI, PR;SELVANAYAGAM, S;VELMURUGAN,D;RAVIKUMAR, K; SURESH BABU, AR;RAGHUNATH, R; 2’-(p-Chlorobenzoyl)-2,2’,3,3’,4’,5’,6’,6’’-octahydro-1H-indan-2-spiro-3’-(1H-pyrolizine)1’-spiro-3’’-indoline-1,2 ‘’ ,3-trioneActa Crystallographica Section E (Structure ReportsOnline) (2004) 60(Part 1) : 0126-0128

SESHADRI, PR;SELVANAYAGAM, S;VELMURUGAN,D;RAVIKUMAR, K;SURESHBABU, AR;RAGHUNATHAN, R;5,7-dibromo-4 ‘-(4-bromobenzoyl)-1 ‘-methyl-1H-indole-3-spiro-2 ‘-pyrrolidine-3 ‘-spiro-3 ‘’-1H-indole-2,2 ‘’(3H,3‘’ H)-dione methanol solvateActa Crystallographica Section E (Structure Reports

Online)(2004) 60(Part 5):O870-O872


195


D;RAVIKUMAR, K;SURESHBABU, AR;RAGHUNATHAN, R;

5,7-dibromo-1 ‘-methyl-2 ‘-(4-methoxybenzoyl)-1H-

indole-3-spiro-2 ‘-pyrrolidine-3 ‘-spiro-3 ‘’-1H-indole-2,2

‘’(3H,3 ‘’ H)-dione methanol solvate

Acta Crystallographica , Section E (Stru Reports Online)

(2004) 60(Part4):O550-O552

SHARMA, GVM;KUMAR, K RAMAN; Studies directed

towards the total synthesis of feigrisolide B


SHARMA, GVM; PENDEM, NAGENDAR; REDDY, K RAVINDER; RADHA

KRISHNA, PALAKODETY; NARSIMULU, K;KUNWAR, AC; The

stereoselective synthesis of C-linked 42 -deoxy aza-

disaccharides from C-linked carbo-â-amino acids


SHARMA, GVM;PRASAD, TR;RAKESH;SRINIVAS, B; p-

methoxy diphenylmethanol (MDPM), p-phenyl

diphenylmethanol (PDPM) , and p-phenylphenyl

diphenymethanol (PPDM – Protecting groups for

alcohols- Protection and deprotection


SHARMA, GVM;REDDY, Ch GOVARDHAN; A stereo

selective synthesis of verbalactone-determination of

absolute stereochemistry


SHARMA, GVM;REDDY, J JANARDHAN;SREE LAKSHMI,

P;RADHAKRISHNA, P; Rapid and facile Lewis acid

catalyzed Boc protection of amines


SHARMA, GVM;REDDY;K LAXMA;SREE LAKSHMI, P;

RADHA KRISHNA, P; An efficient protocol for the

preparation of MOM ethers and their deprotection

using zirconium(IV) chloride


SHARMA, GVM;REDDY, K RAVINDER;RADHA KRISHNA,

P;RAVI SHANKAR, A;JAYAPRAKASH, P;JAGANNADH,

B;KUNWAR, AC; Left handed helical twists in “Mixed b-

Peptides” derived from alternating C-Linked Carb b3-

Amino acids and b-hGly units

Angewandte Chemie International Edition (2004) 43 :

3961-3497

SHARMA, GVM; REDDY, J JANARDHAN;SREE LAKSHMI,

P;RADHA KRISHNA, P; A versatile and practical synthesis

of bis(indolyl)methanes/bis(indolyl)glycoconjugates

catalyzed by trichloro-1,3,5-triazine


SHARMA, GVM;BEGUM, ASRA;RAKESH;RADHA KRISHNA,

P; Zirconium(IV) chloride mediated cyclodehydration of

1,2-diacylhydrazines: a convenient synthesis of 2,5-

diaryl-1,3,4-oxadizole derivatives


SHARMA, GVM;PUNNA, SREENIVAS;RATNAMALA,

A;DURGA KUMARI, V;SUBRAHMANYAM, M; Zeolite-

mediated conversion of alcohols to p-methoxybenzyl

ethers

Organic Preparations and Procedures International

(2004) 36(6) : 581-586

SHARMA, GVM;RADHA KRISHNA, P; Carbohydrates: from

chirons to newglycosubstance

Current Organic Chemistry (2004) 8(13) : 1187-1209

SHARMA, GVM;SUBHASH CHANDER, A;RADHA KRISHNA,

P;KRISHNUDU, K; RAMANA, RAO, MHV;KUNWAR, AC;

Synthesis of pseudo saccharide precursors through ‘Off

template site’ Michael Wittig reaction on sugar derived

enal

Arkivoc (2004) : 12

SHIREEN, KF;MAHBOOB, M;KHAN, AT; Effects of short

term mercury exposure on antioxidants enzymes and

lipid peroxidation in different organs of rat

Toxicology International (2004) 11(1) : 1-7

Publications

196

SINGH, HARJINDER;ARORA, KARUNESH;TAPADAR,

S;CHAKRABORTY, TK; Preferential polymerization of 5-(Aminomethyl)2-Furancarboxylic acid (AMFC) into acyclic tripeptideJournal of Theoretical and Computational Chemistry(2004) 3(4) : 555-556

SMITHA, B;SRIDHAR, S;KHAN, AA; Polyelectrolytecomplexes of chitosan and poly(acrylic acid) as protonexchange membranes for fuel cellsMacromolecules (2004) 37(6) : 2233-2239

SMITHA, B;SRIDHAR, S;KHAN, AA; Synthesis andcharacterization of Sulfonated PEEK membranes for fuelcell applicationsJournal of Polymer Materials (2004) 21(1) : 99-106

SMITHA, B;SUHANYA, D;SRIDHAR, S;RAMAKRISHNA, M;Separation of organic-organic mixtures bypervaporation -a reviewJournal of Membrane Science (2004) 241(1) : 1-21

SREEDHAR, B;SWAPNA, V;SRIDHAR, CH; Bismuth(III)triflate: Novel and efficient catalyst for Claisen and Friesrearrangements of allyl ethers and phenyl estersSynthetic Communications (2004) 34(8) : 1433-1440

SRIDHAR, C; SUBBARAJU, GV; VENKATESWARLU, Y;VENUGOPAL, RT; New acylated iridoid glucosides fromVitex altissimaJournal of Natural Products (2004) 67(12) : 2012-2016

SRIDHAR, S;RAO, A GANGAGNI; Treating Effluents in BulkDrug industry using Reverse OsmosisPharma Bio World (2004) Feb-Apr : 91-97

SRIDHAR, S;SMITHA, B; Performance and Prospects ofNanofiltration for Separations in PharmaceuticalmanufactureJournal of Mass Spectrometry (2004) May-June : 77-83

SRIDHAR, S;SMITHA, B;MADHAVI LATHA, US; RAMAKRISHNA; Pervaporation of 1,4-Dioxane/Water mixturesusing poly(vinyl alcohol) membranes crosslinked withtoluylene-2,4-diisocyanate

Journal of Polymer Materials (2004) 21(2) : 181-188

SRIKANTH, R;BHANUPRAKASH, K;SRINIVAS, R;WONG,

CY;TERLOUW, JK; Protonated silanoic acid His (OH) (2)(+) and its neutral counterpart: a tandem massspectrometric and CBS-QB3 computational studyJournal of Mass Spectrometry (2004) 39(3) : 303-311

SRIKANTH, R;REDDY, P NAGI;SRINIVAS, R;SHARMA,GVM;REDDY, K RAVINDER; Mass spectral study of alkali-cationized Boc-Carbo-b3-peptideselectrospray tandemmass spectrometryRapid Communications in Mass Spectrometry (2004)18(24) : 3041-3050

SRIKANTH, R;SRINIVAS, R;SHARMA, GVM;RAVINDERREDDY, K;RADHA KRISHNA, P; Mass spectral study ofBoc-carbo-ß3-peptides: differentiation of two pairs ofpositional and diastereomeric isomersJournal of Mass Spectrometry (2004) 39(9) : 1068-1074

SRILAXMI, Ch;LINGAIAH, N;HUSSAIN, AHMAD;SAIPRASAD, PS; NARAYANA, KV;MARTIN, A;LUCKE, B; In situsynthesis and ammoxidation activity of ammonium saltof molybdophosphoric acid on VOPO4 catalystsCatalysis Communications (2004) 5(4) : 199-203

SRINIVAS, K;NAIR, CKS;RAMESH, S;PARDHASARADHI, M;An improved synthesis of 5-(2-flurophenyl)-1H-tetrazoleOrganic Preparations & Procedures International(2004) 36(1) : 69-71

SRINIVAS, K;NAIR, CKS;RAMESH, S;PARDHASARADHI, M;A rapid and efficient synthesis of 2-butyl-5-chloro-3H-imidazole-4-carboxaldehydeSynthesis-Stuttgart (2004) (4) : 506-508

SRINIVAS, KVNS;DAS, B; Iodine catalyzed one-potsynthesis of 3,4-dihydropyrimidin-2(1H)-ones andthiones: A simple and efficient procedure for BiginellireactionSynthesis_Stuttgart (2004) (13) : 2091-2093

SRINIVAS, KVNS;DAS, B; An efficient one-pot synthesisof pyrano and furoquinolines employing two reusablesolid acids as heterogeneous catalysts

Synlett (2004) (10) : 1715-1718


197

SRINIVAS, PV;REDDY, S VENKAT;SREELATHA, T; HARA

KISHORE, K;PRAVEEN, B;MURTHY, US;RAO, JM; A new

method of synthesis and antibacterial acitivity

evaluation of piper amides

Natural Product Research (2004) 18(1) : 95-98

SUMAN, RAJ DS;CHARY, NS;BINDU, VH;REDDY, MRP;

ANJANEYULU, Y; Aerobic oxidation of common effluent

treatment plant wastewaters and sludge character-i

zation studies

International Journal of Environmental Studies (2004)

64(1) : 99-111

SUMAN, N JOHN;REDDY, YARAPATHY, V;RAJU, KVSN; TAMMISHETTI,

SHEKHARAM; Effect of epxoy resin on cure behaviour and

thermal properties of cyanate ester resin

International Journal of Plastics Technology (2004)

8(1) : 180

SUNIL SINGH, RAJKUMAR;CHAUDHURI, ARABINDA;

Single additional methylene group in the head-group

region imparts high gene transfer efficacy to a

transfection- incompetent cationic lipid

FEBS Letters (2004) 556(1-3) : 86-90

SUNIL SINGH, RAJKUMAR;GONÇALVES, CHRISTINE;

SANDRIN PIERRE; PICHON, CHANTAL;MIDOUX, PATRICK;

CHAUDHURI, A; On the gene delivery efficacies of pH-

Sensitive Cationic Lipids via Endosomal Protonation: A

Chemical Biology Investigation

Chemistry and Biology (2004) 11(5) : 713-723

SURENDRA, K;KRISHNAVENI, NS;RAO, K RAMA ; A new

and efficient method for the synthesis of thiiranes from

oxirane-cyclodextrin complexes and thiourea in water


SURENDRA, K;KRISHNAVENI, NS;RAO, K RAMA; A s5imple

biomimetic protocol for the oxidation of alcohols with

sodium hypochlorite in the presence of β-cyclodextrin

in water

Canadian Journal of Chemistry (2004) 82(7) : 1230-

1233

SURESH BABU, K;TIWARI, ASHOK K;SRINIVAS, PULLELA

V;ALI, AMTUL Z; RAJU, B CHINA;RAO, JM; Yeast and

mammalian alpha-glucosidase inhibitory constituents

from Himalayan rhubarb Rheum emodi Wall.ex Meisson


14(14) : 3841-3845

SURESH BABU, K;RAJU, BC; RAO, AS; KUMAR, SP; RAO,

JM; Bismuth triflate catalyzed one-pot synthesis of

tetrahydrochromanoquinolines


SURESH, KI;OTHERGRAVEN, JENS;RAJU, KVSN;BARTSCH,

ECKHARD; Mechanistic studies on particle nucleation in

the batch emulsion polymerization of n-butyl acrylate

containing multifunctional monomers

Colloid & Polymer Science (2004) 283(1) : 49-57

SWAMY, NR;GOUD, TV;REDDY, SM;KRISHNAIAH, P;

VENKATESWARLU, Y; Zirconium (IV) chloride catalyzed

ring opening of epoxides with a romatic amines


SWAMY, NR;SRINIVASULU, M;REDDY, T SRIKANTH;GOUD,

TV;VENKATESWARLU, Y; Zirconium (IV) chloride catalyzed

synthesis of 2,3-Unsaturated C,N,O,S, and Heteroa-

romatic glycosylation in the Ferrier rearrangement

Journal of Carbohydrate Chemistry (2004) 23(6&7) :

435-441

M, ML;IWASAWA, Y ; Chiral self-dimerization of vanadium

complexes of a SiO2 surface: the first heterogeneous

catalysts for asymmetric coupling of naphthol


TIWARI, AK; Antioxidants: New-generation therapeutic

base for treatment of polygenic disorders [Review]

Current Science (2004) 86(8) : 1092-1102

USHA RANI, P ; Activity of plant derived extracts and oils

against four genera of bacteria viz Staphylococcus

aureus, Bacillus cereus, Escherichia coli I and Escherichia

coli II

Journal of Applied Zoological Research (2004) 15(2)

Publications

198

USHA RANI, P; Attraction of leaf surface chemicals from

yellow stem borer infested rice plants to its eggparasitoid, Trichogramma japonicum (Ashmead)Egg Parasitoid News (2004) (15) : 19-20

USHA RANI, P; Antennal sensilla of Trichogrammajaponicum an egg parasitoid of rice yellow stem borerand its relation to kairomone perceptionEgg Parasitoid News (2004) (15) : 20

USHA RANI, P;LAKSHMINARAYANA, M;INDU KUMARI, S;Short range kairomones and oviposition stimulantsfrom the host Achea janata (L) infested castor plants toTrichogramma chilonis and Trichogramma achaeaEgg Parasitoid News (2004) (15) : 19

VARALA, RAVI;RAMU, E;ALAM, M MUJAHID;ADAPA,SRINIVAS R; Scope and utility of CsOH×H

2O in amination

reactions via direct coupling of aryl halides and sec-alicyclic aminesSynlett (2004) (10) : 1747-1750

VARALA, R;RAMU, E;ALAM, M MUJAHID;ADAPA,SRINIVAS, R; CsOH·H2O-promoted synthesis of arylsulfides via direct coupling of aryl halides and thiolsChemistry Letters (2004) 33 (12) : 1614-1615

VEDARAMAN, N;BRUNNER, G;KANNAN, CSRINIVASA;MURALIDHARAN, C;RAO, PG;RAGHAVAN, KV;Extraction of cholesterol from cattle brain usingsupercritical carbon dioxideThe Journal of Supercritical Fluids (2004) 32(1-3) :231-242

VENKAT NARSAIAH, A;BASAK, AK; NAGAIAH, K;Cadmium chloride: An efficient catalyst for one-potsynthesis of 3,4-dihydropyrimidin-2(1H)-onesSynthesis-Stuttgart (2004) (8) : 1253-1256

VENKAT NARSAIAH, A;BASAK, AK;VISALI, B;NAGAIAH, K;An eco friendly synthesis of electrophilic alkenescatalyzed by dimethylaminopyridine under solvent-free conditionsSynthetic Communications (2004) 34(16) : 2893-

2901392.

VENKAT NARSAIAH, A;NAGAIAH, K; An efficient and

improved method for the preparation of nitrides from

primary amides and aldoximes


1271-1274

VENKAT NARSAIAH, A;NAGAIAH, K; An Eco-friendly

synthesis of diaryl ethers without catalyst under micro

wave irradiation

Indian Journal of Chemistry, Section-B (2004) (11) :

2478-2481

VENKATESWARLU, CH; Advances in Monitoring and State

Estimation of Bioreactors

Journal of Scientific and Industrial Research (2004)

63 : 491-498

VENKATESWARLU, CH;ANURADHA, R; Dynamic Fuzzy

Adaptive Controller for pH

Chemical Engineering Communications (2004) 191 :1564-1588

VENKATESWARLU, CH;GANGIAH, K; Constrained

generalized predictive control of unstable nonlinear

processes

Chemical Engineering Research and Design (2004)

75(3) : 371-376

VENUGOPAL, A;SCURRELL, MS; Low temperature

reductive pretreatment of Au/Fe2O

3catalysts, TPR/TPO

studies and behaviour in the water-gas shift reaction


VENUGOPAL, D;SRINIVAS, B;SHARMA, M VENKATA

PHANIKRISHNA;PANDA, LIPSA; ANIL KUMAR, PULLUR;

SUBRAHMANYAM, M;DURGA KUMARI, V; Hydrogenation of

acetophenone over bifunctional multimetal oxide catalysts

Reaction Kinetics and Catalysis Letters (2004) 83(1) :

63-70

VIJAY, DOLLY;PRIYAKUMAR, UD;SASTRY, G NARAHARI;

Bas9is set and method dependence of the relative

energies of C2S2H2 isomers

Chemical Physics Letters (2004) 383(1-25) : 192-197


199

VIJAY NAIR;SMITHA M, NAIR;MATHAI, SINDHUJURGEN

LIEBSCHER, BURKHARD ZIEMER AND NARSIMULU, K; The

Rh(II) catalyzed reaction of diethyl diazomalonate with

thietanes: a facile synthesis of tetrahydrothiophene

derivatives via sulfonium ylides


VIJEETA, T;REDDY, JRC;RAO, BVSK;KARUNA, MSL;PRASAD,

RBN; Phospholipase-mediated preparation of 1-

ricinoleoyl-2-acyl-sn-glycero-3-phosphocholine from

soya and egg phosphatidylcholine

Biotechnology Letters (2004) 26(13) : 1077-1088

VINOD KUMAR, VALLURIPALLI;CHAUDHURI, ARABINDA;

On the disulfide-linker strategy for designing efficacious

cationic transfection lipids: an unexpected transfection

profile

FEBS Letters (2004) 571(1-3) : 205-211

YADAV, JS;RAJAIAH, G; A convergent synthesis of the

C31-C46 fragment of phorboxazoles

Synlett (2004) (9) : 1537-1540

YADAV, JS;RAJAIAH, G; A convergent synthesis of the

C31-C46 fragment of phorboxazoles

Synlett (2004) (10) : 1743-1746

YADAV, JS;REDDY, BVS; BASAK, AK;NARSAIAH, A VENKAT;

Recyclable 2nd generation ionic liquids as green solvents

for the oxidation of alcohols with hypervalent iodine

reagents

Tetrahedron (2004) 60(9) : 2131-2135

YADAV, JS;REDDY, BVS;BASAK, AK;NARSAIAH, A VENKAT;

Baeyer-Villiger oxidations in ionic liquids. A facile

conversion of ketones to esters and lactones


YADAV, JS;REDDY, BVS;BASAK, AK;VISALI, B;NARSAIAH,

AV;NAGAIAH, K; Phosphane-catalyzed knoevenagel

condensation: A facile synthesis of alpha-cyanoacrylates

and alpha-cyanoacrylonitriles

European Journal of Organic Chemistry (2004) (3) :

546-551

YADAV, JS;REDDY, BVS;BAISHYA, G;REDDY, PV; HARSHA

VARDHAN, SJ; Bismuth triflate as novel and efficient

catalyst for the synthesis of beta-aminosulfides


YADAV, JS;REDDY, BVS;ESHWARAIAH, B;GUPTA, MANOJ

KUMAR; Bi(Otf )3/[bmim]BF4 as novel and reusable

catalytic system for the synthesis of furan, pyrrole and

thiophene derivatives


YADAV, JS;REDDY, BVS;ESHWARAIAH, B;SRINIVAS, M;

Montmorillonite KSF clay catalyzed one-pot synthesis

of –aminonitriles

Tetrahedron (2004) 60(8) : 1767-1771

YADAV, JS;REDDY, BVS;GUPTA, MK;BISWAS, SK; Rapid and

efficient protocol for the synthesis of 4-chlorotetra

hydro pyrans using niobium(V) chloride


YADAV, JS;REDDY, BVS;GUPTA, MK;PRABHAKAR, A;

JAGADEESH, B; First example of ring expansion of

activated quinolines and isoquinolines: Novel

benzoazepines

Chemical Communications (2004) 10(18) : 2124-2125

YADAV, JS;REDDY, BVS;NAVEENKUMAR, V;RAO,

RS;NAGAIAH, K; [Bmim] PF6/CuBr: a novel and recyclable

catalytic system for the synthesis of propargyl amines


YADAV, JS;NAIDU, JJ;SADASHIV, K ; NBCL5-catalyzed

rapid and efficient synthesis of 3,4dihydro

pyrimidinones under ambient conditions


YADAV, JS;REDDY, BVS;PADMAVANI, B; Incl3-catalyzed

tandem Michael/Friedel-crafts cyclization: a novel

protocol for chiral 2,4-disubstitutedtetra hydro

quinolines


Publications

200

YADAV, JS;REDDY, BVS;PARIMALA, G;RAJU, A KRISHNAM;

Bismuth triflate catalyzed condensation of –hydroxy-

unsaturated aldehydes with aryl amines


YADAV, JS;REDDY, BVS;REDDY, Ch SRINIVAS; SelectfluorTM: a novel and efficient reagent for the synthesis of –

hydroxy thiocyanates


YADAV, JS;REDDY, BVS;REDDY, KS;CHANDRAIAH,

L;SUNITHA, V; Bi(Otf )3 as novel and efficient catalyst for

the stereoselective synthesis of C-pseudoglycals


YADAY, JS;REDDY, BVS;REDDY, RSR;BASAK, AK;

NARSAIAH, AV; Efficient halogenation of aromatic

systems using N-halosuccinimides in ionic liquids

Advanced Synthesis & Catalysis (2004) 346(1) : 77-82

YADAV, JS; REDDY, BVS; SADASHIV, K; PADMAVANI, B; [4+2]

Cycloaddition of ortho-quinone methides promoted

by ionic liquids: An efficient and mild protocol for the

synthesis of tetrahydropyranobenzopyrans


610

YADAV, JS;REDDY, BVS;SADASHIV, K;RAGHAVENDRA,

S;HARIKISHAN, K; Montmorillonite KSF/SiO2 as novel

and recyclable solid acids for the synthesis of-

aminohalides and-azidoamines


YADAV, JS;REDDY, BVS;REDDY, MS;NIRANJAN, N; Eco-

friendly heterogeneous solid acids as novel and

recyclable catalysts in ionic medium for

tetrahydropyranols


210(1-2) : 99-103

YADAV, JS;REDDY, BVS;SATHEESH, G;NAGA LAKSHMI,

P;KIRAN KUMAR, S; KUNWAR, AC; Rapid and efficient

synthesis of optically active pyrazoles under solvent-

free conditions


YADAV, JS;REDDY, BVS;SREEDHAR, P;RAO, RS;NAGAIAH,

K; Silver phosphotungstate: A novel and recyclable

heteropoly acid for Friedlander quinoline synthesis

Synthesis (2004) (14) : 2381-2385

YADAV, JS;REDDY, BVS;SRIDHAR, P;REDDY, JSS;NAGAIAH,

K;LINGAIAH, N;SAIPRASAD, PS; Green protocol for the

biginelli three-component reaction: Ag3PW12040 as a

novel, water-tolerant heteropolyacid for the synthesis

of 3,4-dihydropyrimidinones

European Journal of Organic Chemistry (2004) (3) :

552-557

YADAV, JS;REDDY, BVS;SRINIVAS, M;PADMAVANI, B;

CeCl3.H

20/NaI-Promoted stereoselective synthesis of 2,4-

disubstituted chiral tetrahydroquinolines

Tetrahedron (2004) 60(14) : 3261-3266

YADAV, JS;REDDY, BVS;SHUBASHREE, S;SADASHIV, K;

Iodine/MeOH: a novel and efficient reagent system for

thiocyanation of aromatics and heteroaromatics


YADAV, JS;REDDY, BVS;SHUBASHREE, S;SADASHIV,

K;NAIDU, JJ; Ionic liquids-promoted multi-component

reaction: Green Approach for highly substituted 2-

aminofuran derivatives

Synthesis (2004) (14) : 2376-2378

YADAV, JS;REDDY, BVS;SWAMY, T; InBr3-catalyzed

conjugate addition of Indoles to p-quinones: An efficient

synthesis of 3-indolylquinones



201

YADAV, JS;REDDY, BVS;SWAMY, T;RAMIREDDY, N; Ionic

liquids-promoted addition of arylsulfinic acids to P-

quinones- A green synthesis of diaryl sulfones


YADAV, JS;REDDY, BVS;SATHEESH, G; Montmorillonite

clay catalyzed alkylation of pyrroles and indoles with

cyclic hemi-acetals


YADAV, JS;REDDY, BVS;NARSIMHASWAMY, D;NAGA

LAKSHMI, P;NARSIMULU, K;SRINIVSULU, G;KUNWAR, AC;

Domino Knoevenagel hetero-Diels–Alder reactions: a

stereoselective synthesis of sugar fused furo[3,2-

b]pyrano[4,3-d]pyran derivatives


YADAV, JS;REDDY, BVS;REDDY, Ch SURESH; InCl3/IBX: a

novel reagent system for the conversion of glycals into

,-unsaturated -lactones


YADAV, JS;REDDY, BVS;PREMALATHA, K;Bi(OTf )(3)-

catalyzed friedlander hetero-annulation: A rapid

synthesis of 2,3,4-trisubstituted quinolines

Synlett (2004) (6) : 963-966

YADAV, JS;REDDY, BVS;PRAVEENKUMAR, S;NAGAIAH,

K;LINGAIAH, N; SAIPRASAD, PS; Ag3PW12O40: A novel

and recyclable heteropoly acid for the synthesis of 1,5-

benzodiazepines under solvent-free conditions


YADAV, JS;REDDY, BVS;REDDY, CS;RAJASEKHAR, K; Green

protocol for the synthesis of vicinal-halohydrins from

oxiranes using the [Bmim]PF6/LiX reagent system


YADAV, JS;REDDY, BVS;SADASHIV, K;HARIKISHAN,

K;NARSAIAH, AV; Acylative cleavage of aziridines with

acid anhydrides catalyzed by Scandium triflate


220(2) : 153-157

YADAV, JS;REDDY, BVS;SRINIVAS, M;PRABHAKAR,

A;JAGADEESH, B; Montmorillonite KSF clay-promoted

synthesis of enantiomerically pure 5-substituted

pyrazoles from 2,3-dihydro-4H-pyran-4-ones


YADAV, JS;REDDY, BVS;SWAMY, T;RAO, K RAGHAVENDER;

Bi(Otf )3-catalyzed acylation of p-quinones: a facile

synthesis of acylated hydroquinones


YADAV, JS;REDDY, BVS;VENUGOPAL, Ch;PADMAVANI, B;

InCl3/SiO2-catalyzed-amination of 1,3-dicarbonyl

compounds under microwave irradiation


YADAV, JS;REDDY, K BHASKAR;SABITHA, G; An efficient

synthesis of (+)-prelactone B;


YADAV, JS;REDDY, BVS;RAO, K VISHWESHWAR;RAJ, K

SARITA;RAO, P PURUSHOTHAMA;PRASAD, AR; GUNA

SEKAR, D; First example of molecular iodine-catalyzed

allylation and alkynylation of cyclic allylic acetates


YADAV, JS;SRIHARI, P; Formal total synthesis of (-)-

salicylihalamides A and B


Publications

202

YADAV, JS;REDDY, BVS;PADMAVANI, B;GUPTA, MANOJ

KUMAR; Gallium(III) halide-catalyzed coupling of indoles

with phenylacetylene: synthesis of bis(indolyl)

phenylethanes


YADAV, JS;PRAVEEN KUMAR, S;KONDAJI, G;SRINIVASA

RAO, R;NAGAIAH, K; A novel L-proline catalyzed biginelli

reaction: one-pot synthesis of 3,4-dihydropyrimidin-

2(1H)-ones under solvent free conditions


YADAV, JS;REDDY, BVS;NAVEEN KUMAR, V;SRINIVASA

RAO, R;NAGAIAH, K; First example of ionic liquids-

promoted domino knoevenagel hetero-diels-alder

reactions: A facile synthesis of pyrano[3,2-c] coumarins


YADAV, JS;REDDY, BVS;REDDY, P NARAYANA; Rh2(Oac)

4

immobilized in [bmim]PF6: a novel and recyclable

catalytic system for the cyclopropanation of alkenes


56


YADAV, JS;REDDY, BVS;REDDY, P NARAYANA; Bi(Otf )3-

[Bmim]PF6: A novel and recyclable catalytic system for

the diasteroselective synthesis of cis-fused pyrano and

furanobenzopyrans


YADAV, JS;REDDY, BVS;GUPTA, MANOJ KUMAR; Ferric(III)

chloride promoted efficient thiocyanation of

arylalkanes: A facile synthesis of dithiocyanates


YADAV, JS;REDDY, BVS;SRINIVAS, M; A novel and efficient

method for the synthesis of a-Azidoketones and a-

Ketothiocyanates


YADAV, JS;REDDY, BVS;REDDY, V SUNITHA;REDDY, K

SRINIVASA;RAMAKRISHNA, KVS; Montmorillonite KSF-

catalyzed one-pot synthesis of hexahydro-1H-

pyrrolo[3,2-c]quinoline derivatives


biennial report 2003-05

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