light sources for optical coherence tomography · • optical coherence tomography has become a key...

Company Confidential

19-March-2014

Dr. Christian Vélez, Founder and CEO

Light Sources for Optical Coherence

Tomography

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Outline

• Products

• Markets

• Applications

• Optical Coherence Tomography

o Superluminescent LED (SLED) solutions

o Swept Source (fast tunable Laser) solutions

• Summary

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• HQ in Schlieren/Zürich • Employees: 30• Revenue: ~CHF 10m • Profitable• Shipped >200k devices

since 2003

Focused on engineering, sales and marketing of• Superluminescent Diodes (EXS)• Broadband Sources (EBS)• Wavelength-Swept Lasers (ESS)• SLED-based Transceivers (TxRx)• Balanced Receivers (EBR)

EXALOS

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SLEDs: a bridge between LDs and LEDsSLEDs: a bridge between LDs and LEDs

LEDLEDLEDLED

Inte

nsity

Wavelength

No cavity, No No cavity, No No cavity, No No cavity, No gaingaingaingainNo feedbackNo feedbackNo feedbackNo feedback

Spontaneous Emission(broadband, not directional)

Spontaneous Emission(broadband, not directional)

FP LDFP LDFP LDFP LD

Inte

nsity

Wavelength

Laser cavity, Laser cavity, Laser cavity, Laser cavity, gain, gain, gain, gain, feedbackfeedbackfeedbackfeedback

Stimulated Emission(narrowband, directional)

Stimulated Emission(narrowband, directional)

SLEDSLEDSLEDSLED

Inte

nsity

Wavelength

SingleSingleSingleSingle----passpasspasspassgain in waveguidegain in waveguidegain in waveguidegain in waveguide

ASE(broadband, directional)

ASE(broadband, directional)

What are Superluminescent Diodes ?

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> Speckle PerformanceSpeckle PerformanceSpeckle PerformanceSpeckle Performance

> LDLDLDLD > SLEDSLEDSLEDSLED

Blue LDs strong specklesBlue LDs strong specklesBlue LDs strong specklesBlue LDs strong speckles SLED light at 425nm with strongly SLED light at 425nm with strongly SLED light at 425nm with strongly SLED light at 425nm with strongly reduced speckle patternreduced speckle patternreduced speckle patternreduced speckle pattern

Speckle performace comparison SLED/LD

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EXALOS’ SLED modules

www.exalos.comwww.exalos.comwww.exalos.comwww.exalos.com

GaAs InP

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Fiber Optics Gyroscopes (FOG)Navigation system (air, space, sea, land)

Other applicationsMachine vision, metrology, etc.

Fiber Optics Sensors (FOS)Strain, pressure, current

Fiber Optic Test Equipment (FOT)Optical channel monitors

Optical Coherence Tomography (OCT)Medical Imaging

EXALOS Main Markets

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Optical Coherence Tomography Optical Coherence Tomography Optical Coherence Tomography Optical Coherence Tomography (OCT)(OCT)(OCT)(OCT)

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Time-Domain (TD-) OCT

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Penetration vs Resolution

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OCT for Ophthalmology• OCT imaging used for …

o Anterior lens surface and Anterior lens surface and Anterior lens surface and Anterior lens surface and anterior chamber/segmentanterior chamber/segmentanterior chamber/segmentanterior chamber/segment� refractive surgery on cornea� cataract & lens replacement

o Posterior lens surfacePosterior lens surfacePosterior lens surfacePosterior lens surface� lens replacement (IOL)

o RetinaRetinaRetinaRetina� AMD, diabetic retinopathy, etc.

Fovea = Point of central focus

Anterior chamberBlind spot

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OCT and Histology

• Goal of any imaging technology = visualization of structures that are found with histology !

• Fast spectral-domain OCT systems (and in combination with higher resolution of few microns) have demonstrated that OCT in ophthalmology is equally informative as histology but is nonnonnonnon----invasive, real time and ininvasive, real time and ininvasive, real time and ininvasive, real time and in----vivo vivo vivo vivo !

Fovea

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Medical OCT ImagingE. Swanson: “Photonics Markets: OCT – History and Current Status”, Feb 2013

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Non-Medical OCT ImagingE. Swanson: “Photonics Markets: OCT – History and Current Status”, Feb 2013

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400-2k A-scansper second

20k-70k A-scansper second

10k-200k (6000k) A-scansper second

OCT Evolution

SLED

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Spectral-Domain (SD-) OCT

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Swept Source (SS-) OCT

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Swept SourcesSwept SourcesSwept SourcesSwept Sourcesfor OCTfor OCTfor OCTfor OCT

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Swept Source Optical

Wavelength1250nm 1350nm

OpticalPower 0.05 nm (1/2000)

SLEDOpticalWavelength

1250nm 1350nm

OpticalPower 100 nm

A high-speed narrowband optical filter with wide tuning range is needed

SLED vs Swept Source

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butterfly package

Output coupler mirror

R-SOA

MEMS scanners

Gratings

λ(t)

P

Microlenses

EXALOS: ECL with MEMS Scanner

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Summary

• Optical Coherence Tomography has become a key technology for medical imaging

• A must for Ophthalmic and Cardio applications

• Light sources are a key enabler of today OCT systems

• Incumbent SLED technology is more and more been replaced by Swept Laser

• EXALOS has mange to position itself as a key player in this market

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Thank YouThank YouThank YouThank You

velez@exalos.comvelez@exalos.comvelez@exalos.comvelez@exalos.com