light sources for optical coherence tomography · • optical coherence tomography has become a key...

22
Company Confidential 19-March-2014 Dr. Christian Vélez, Founder and CEO Light Sources for Optical Coherence Tomography

Upload: others

Post on 01-Jun-2020

2 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

Company Confidential

19-March-2014

Dr. Christian Vélez, Founder and CEO

Light Sources for Optical Coherence

Tomography

Page 2: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

2 | 27-Mar-14 | Company Confidential

Outline

• Products

• Markets

• Applications

• Optical Coherence Tomography

o Superluminescent LED (SLED) solutions

o Swept Source (fast tunable Laser) solutions

• Summary

Page 3: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

3 | 27-Mar-14 | Company Confidential

• HQ in Schlieren/Zürich • Employees: 30• Revenue: ~CHF 10m • Profitable• Shipped >200k devices

since 2003

Focused on engineering, sales and marketing of• Superluminescent Diodes (EXS)• Broadband Sources (EBS)• Wavelength-Swept Lasers (ESS)• SLED-based Transceivers (TxRx)• Balanced Receivers (EBR)

EXALOS

Page 4: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

4 | 27-Mar-14 | Company Confidential

SLEDs: a bridge between LDs and LEDsSLEDs: a bridge between LDs and LEDs

LEDLEDLEDLED

Inte

nsity

Wavelength

No cavity, No No cavity, No No cavity, No No cavity, No gaingaingaingainNo feedbackNo feedbackNo feedbackNo feedback

Spontaneous Emission(broadband, not directional)

Spontaneous Emission(broadband, not directional)

FP LDFP LDFP LDFP LD

Inte

nsity

Wavelength

Laser cavity, Laser cavity, Laser cavity, Laser cavity, gain, gain, gain, gain, feedbackfeedbackfeedbackfeedback

Stimulated Emission(narrowband, directional)

Stimulated Emission(narrowband, directional)

SLEDSLEDSLEDSLED

Inte

nsity

Wavelength

SingleSingleSingleSingle----passpasspasspassgain in waveguidegain in waveguidegain in waveguidegain in waveguide

ASE(broadband, directional)

ASE(broadband, directional)

What are Superluminescent Diodes ?

Page 5: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

5 | 27-Mar-14 | Company Confidential

> Speckle PerformanceSpeckle PerformanceSpeckle PerformanceSpeckle Performance

> LDLDLDLD > SLEDSLEDSLEDSLED

Blue LDs strong specklesBlue LDs strong specklesBlue LDs strong specklesBlue LDs strong speckles SLED light at 425nm with strongly SLED light at 425nm with strongly SLED light at 425nm with strongly SLED light at 425nm with strongly reduced speckle patternreduced speckle patternreduced speckle patternreduced speckle pattern

Speckle performace comparison SLED/LD

Page 6: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

6 | 27-Mar-14 | Company Confidential

EXALOS’ SLED modules

www.exalos.comwww.exalos.comwww.exalos.comwww.exalos.com

GaAs InP

Page 7: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

7 | 27-Mar-14 | Company Confidential

Fiber Optics Gyroscopes (FOG)Navigation system (air, space, sea, land)

Other applicationsMachine vision, metrology, etc.

Fiber Optics Sensors (FOS)Strain, pressure, current

Fiber Optic Test Equipment (FOT)Optical channel monitors

Optical Coherence Tomography (OCT)Medical Imaging

EXALOS Main Markets

Page 8: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

8 | 27-Mar-14 | Company Confidential

Optical Coherence Tomography Optical Coherence Tomography Optical Coherence Tomography Optical Coherence Tomography (OCT)(OCT)(OCT)(OCT)

Page 9: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

9 | 27-Mar-14 | Company Confidential

Time-Domain (TD-) OCT

Page 10: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

10 | 27-Mar-14 | Company Confidential

Penetration vs Resolution

Page 11: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

11 | 27-Mar-14 | Company Confidential

OCT for Ophthalmology• OCT imaging used for …

o Anterior lens surface and Anterior lens surface and Anterior lens surface and Anterior lens surface and anterior chamber/segmentanterior chamber/segmentanterior chamber/segmentanterior chamber/segment� refractive surgery on cornea� cataract & lens replacement

o Posterior lens surfacePosterior lens surfacePosterior lens surfacePosterior lens surface� lens replacement (IOL)

o RetinaRetinaRetinaRetina� AMD, diabetic retinopathy, etc.

Fovea = Point of central focus

Anterior chamberBlind spot

Page 12: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

12 | 27-Mar-14 | Company Confidential

OCT and Histology

• Goal of any imaging technology = visualization of structures that are found with histology !

• Fast spectral-domain OCT systems (and in combination with higher resolution of few microns) have demonstrated that OCT in ophthalmology is equally informative as histology but is nonnonnonnon----invasive, real time and ininvasive, real time and ininvasive, real time and ininvasive, real time and in----vivo vivo vivo vivo !

Fovea

Page 13: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

13 | 27-Mar-14 | Company Confidential

Medical OCT ImagingE. Swanson: “Photonics Markets: OCT – History and Current Status”, Feb 2013

Page 14: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

14 | 27-Mar-14 | Company Confidential

Non-Medical OCT ImagingE. Swanson: “Photonics Markets: OCT – History and Current Status”, Feb 2013

Page 15: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

15 | 27-Mar-14 | Company Confidential

400-2k A-scansper second

20k-70k A-scansper second

10k-200k (6000k) A-scansper second

OCT Evolution

SLED

Page 16: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

16 | 27-Mar-14 | Company Confidential

Spectral-Domain (SD-) OCT

Page 17: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

17 | 27-Mar-14 | Company Confidential

Swept Source (SS-) OCT

Page 18: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

18 | 27-Mar-14 | Company Confidential

Swept SourcesSwept SourcesSwept SourcesSwept Sourcesfor OCTfor OCTfor OCTfor OCT

Page 19: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

19 | 27-Mar-14 | Company Confidential

Swept Source Optical

Wavelength1250nm 1350nm

OpticalPower 0.05 nm (1/2000)

SLEDOpticalWavelength

1250nm 1350nm

OpticalPower 100 nm

A high-speed narrowband optical filter with wide tuning range is needed

SLED vs Swept Source

Page 20: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

20 | 27-Mar-14 | Company Confidential

butterfly package

Output coupler mirror

R-SOA

MEMS scanners

Gratings

λ(t)

P

Microlenses

EXALOS: ECL with MEMS Scanner

Page 21: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

21 | 27-Mar-14 | Company Confidential

Summary

• Optical Coherence Tomography has become a key technology for medical imaging

• A must for Ophthalmic and Cardio applications

• Light sources are a key enabler of today OCT systems

• Incumbent SLED technology is more and more been replaced by Swept Laser

• EXALOS has mange to position itself as a key player in this market

Page 22: Light Sources for Optical Coherence Tomography · • Optical Coherence Tomography has become a key technology for medical imaging • A must for Ophthalmic and Cardio applications

22 | 27-Mar-14 | Company Confidential

Thank YouThank YouThank YouThank You

[email protected]@[email protected]@exalos.com