gold standards in medical field
Post on 04-Apr-2015
906 Views
Preview:
DESCRIPTION
TRANSCRIPT
www.medicalresourcelinks.com
GOLD STANDARDS IN MEDICAL FIELD
Published By Medical Resource LinksAll rights reserved 2011Note : Please refer to www.medicalresourcelinks.com/tac.html for detailed information on terms and conditions for using this booklet.
www.medicalresourcelinks.com
www.medicalresourcelinks.com
What is a 'gold standard'?
The term 'gold standard' can be referred to a test or a method. A test which
shows the true status of the patient is termed gold standard. These test are assumed
to have 100% sensitivity and specificity. Diagnostic power of other tests are
evaluated based on the comparison with the gold standard test.When the term
applies to a method or a procedure, a 'gold standard' serves as a basis for evaluation
of other methods.
Gold standard method for estimating resting energy expenditure - indirect
calorimetry
Gold standard investigation for diagnosis of Iron deficiency anemia – Estimation of
serum Ferritin
Gold standard for proving that the life span of red cell is decreased ( useful in
Hemolytic anemia) - Red cell survival study
Gold standard for evaluation of stem cell transplantation therapy - Hemopoietic stem
cell transplantation
Gold standard technique for differentiating allograft rejection and reactivation of
disease after heart transplantation - Endo-myocardial Biopsy
Gold standard investigation for diagnosis of DVT - Contrast venography
Gold standard investigation for diagnosis of acute pharyngitis - Throat culture
www.medicalresourcelinks.com
www.medicalresourcelinks.com
Gold standard investigation for diagnosis of pertussis - Culture of nasopharyngeal
secretions
Gold standard investigation for diagnosis of Otitis externa caused by P. aeruginosa -
Technetium99 bone scan
Gold standard investigation for diagnosis of Acoustic Neuroma – Gadolinium MRI
Gold standard investigation for diagnosis of Shigella infection - isolation and
identification of pathogen from fecal material
Gold standard investigation for diagnosis of Tuberculous meningitis - Culture of
CSF
Gold standard investigation for diagnosis of HSV Encephalitis - Brain biopsy (CSF
PCR largely replaced brain biopsy in recent times)
Gold standard investigation for diagnosis of histoplasmosis - Fungal Culture
Gold standard investigation for diagnosis of hypertrophic cardiomypathy and atrial
myxoma - Echocardiogram
Gold standard investigation for imaging heart valves and valve motion abnormalities
- 2D echocardiography
Gold standard investigation for assessment of Myocardial viability (Identification of
ischemic or hibernating myocardium)– PET
Gold standard investigation for assessment of LV mass and volume - MRI
Gold standard method for evaluation of renal arteries and identification of renal
artery lesions - Contrast arteriography
www.medicalresourcelinks.com
www.medicalresourcelinks.com
Gold standard method for evaluation of respiratory gas exchange - ABG
Gold standard investigation for assessment of albuminuria - 24 hr urine collection
Gold standard investigation for diagnosis of PNH (Paroxysmal Nocturnal
Haemoglobinuria) – Flow cytometry
Gold standard investigation for diagnosis of ATTR and other AF mutations - DNA
sequencing
Gold standard method for identifying and quantifying atherosclerosis in cerebral
arteries - x-ray cerebral angiography
Gold standard investigation for evaluating anatomy of arterio venous malformation -
x-ray angiography
Gold standard for diagnosis and classification of ataxia - genotype
Gold standard investigation for diagnosis of of lung infection (Radiotherapy
induced) in a cancer patient - open-lung biopsy
Gold standard medical treatment for symptomatic progressive pulmonary
hypertension – Prostacyclin
Gold standard investigation for diagnosis of PIH – Serum Urea
Gold standard for assessment of visual impairment - Snellen's chart
Gold standard method of treatment of non-castrate metastatic disease - surgical
orchidectomy
Gold standard method for bacterial stain analysis - Pulse-field gel electrophoresis
Gold standard method of treatment of DCIS - Mastectomy
www.medicalresourcelinks.com
www.medicalresourcelinks.com
Gold standard approach for resection of anterior and middle mediastinal masses -
median or lateral thoracotomy
Gold standard method of treatment of Coarctation of aorta - Surgical repair
Gold standard method for evaluation of coronary artery disease - cardiac
Catheterization
Gold standard method for culture of V. cholerae o139 - Conventional culture
methods
Gold standard to determine cut-off titre of widal test for diagnosis of Typhoid fever
– Nested PCR
Gold standard treatment of brucellosis in adults - IM Streptomycin + Doxycyclin
Gold standard investigation for diagnosis of of chronic arterial mesentric ischemia -
angiography
Gold standard method for treatment of chronic ulcerative colitis - Total
proctocolostomy with end ileostomy
Gold standard method for evaluation of imaging modalities for liver tumours -
Intraoperative ultrasonography
Gold standard investigation for diagnosis of common bile duct stones - Endoscopic
cholangiography
Gold standard investigation for measurement of GFR - inulin clearance
Gold standard for treatment of organ confined, muscle invasive, bladder cancer is -
radical cystoprostatectomy in men and anterior pelvic exenteration in woman
www.medicalresourcelinks.com
www.medicalresourcelinks.com
Gold standard for treatment of femoral shaft fractures - reamed locked
intramedullary nailing
Gold standard method in case of difficult intubation - flexible fibreoptic intubation
scope
Gold standard method for diagnosis and treatment of Ventilator Associated
Pneumonia (VAP) - Broncho alveolar lavage
Gold standard treatment of hyperparathyroidism - Surgery
Gold standard investigation to differentiate follicular and papillary carcinoma of
thyroid gland- histology
Gold standard procedure for thymectomy - Trans cervical mediastinoscopy and
surgery
Gold standard for treatment of adrenal tumours - laparoscopic adrenalectomy
Gold standard investigation for diagnosis of breast cancer - mammography
Gold standard method for staging of breast cancer - Axillary lymph node dissection
Gold standard for evaluation of a stable patient with suspected vascular injury -
angiography
Gold standard investigation for diagnosis of GERD - Ambulatory 24 hr PH
monitoring
Gold standard method for treatment of GERD - Laparoccopic Nissens
fundoplication
Gold standard for evaluating cure rate in duodenal ulcer patients – vagotomy
www.medicalresourcelinks.com
www.medicalresourcelinks.com
Gold standard finding for the diagnosis of GI perforation - finding
pneumoperitoneum
Gold standard for diagnosis of Zollinger-Ellison syndrome - Serum gastrin
levels( Most patients have serum gastrin levels above 1000pg/mL)
Gold standard investigation for diagnosis of colonic mucosal disease - colonoscopy
Gold standard investigation for diagnosis of steatorrhoea - timed quantitative stool
fat determination
Gold standard method for treatment of incontinence with an isolated sphincter defect
- overlapping sphincteroplasty
Gold standard investigation for diagnosis and method of management of Acute
arterial occlusion – laparotomy
Gold standard method for confirmation of mesentric arterial occlusion - mesentric
angiography
Gold standard investigation for diagnosis of celiac disease – Small intestine biopsy
Gold standard for identifying choledocholithiasis – ERCP
Gold standard method of treatment of Symptomatic cholelitiasis – Lap
cholecystectomy
Gold standard method for diagnosis of Primary sclerosing cholangitis - ERCP
Gold standard investigation for diagnosis of Hepatitis C – HCV RNA assay
Gold standard test for diagnosis of intraluminal bile duct abnormalities - ERCP
Gold standard method for management of hydatid disease – surgery
www.medicalresourcelinks.com
www.medicalresourcelinks.com
Gold standard for assessing degree of liver injury and fibrosis - Liver Biopsy
Gold standard method for management of blunt hepatic trauma - non-operative
management
Gold standard test for assessment of function of sphincter of oddi – manometry
Gold standaard investigation of diagnosis of Klatskin tumor - Cholangiography
Gold standard investigation for diagnosis of invasive amoebiasis - ELISA
REFERENCES
1. Harrison's principles of Internal Medicine 17th Edition
2. Schwartz's Manual of Surgery 8th Edition
For more ebooks visit us at www.medicalresourcelinks.com/download.html
Please subscribe to the newsletter at www.medicalresourcelinks.com/subscribe.html
for getting information about latest downloads.
www.medicalresourcelinks.com
top related