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Thursday, 17 December – Friday 18 December 2015Brisbane Convention and Exhibition Centre
Co-ordinated by Professor Ken O’Byrne
Innovative healthcare through partnerships
brisbane diamantina health partners
Brisbane Cancer Conference
Preliminary Program
Brisbane Cancer Conference | December 17 – 18, 2015
Conference Sponsors
Montreux, 18 au 20 mars 2010 Fairmont Le Montreux Palace***** Grand-Rue 100, CH-1820 Montreux Tel: +41 21 962 12 12 Fax: +41 21 962 17 17 www.fairmont.com/montreux Email: montreux@fairmont.com
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Brisbane Convention and Exhibition Centre
14th November, 2015
Dear Colleagues,
Welcome again to the Brisbane Cancer Conference. With the establishment of the Brisbane Diamantina Health Partners, this meeting is an opportunity to draw together cancer researchers in Brisbane and Queensland to advance collaborative efforts in cancer research. The meeting comprises plenary lectures and workshops on recent scientific, technological, nursing and medical advances in the diagnosis and treatment of malignant disease.
On Thursday 17th December there will be 3 satellite symposia in the morning followed by plenary lectures from 2 – 4pm and subsequently workshops in these areas running from 4:30 – 6:30pm. This will be followed by a “Welcome Reception”, with food, drink and entertainment and a chance to socialise with colleagues particularly from other institutions in the city and from Queensland. The all-day meeting on 18th December will include plenary lectures followed by tumour-site specific workshops in the morning and afternoon. A key session will be lectures by Brisbane oncology researchers that have contributed to global advances in our understanding of the epidemiology, molecular biology and treatment of malignant disease including supportive care.
Approximately 500 people registered for the event last year demonstrating the need and potential value of an annual Brisbane Cancer Conference.
This conference is made possible through the support of the PA Research Foundation, Cancer Council Queensland, Brisbane Diamantina Health Partners, our sponsors, the time and effort of the chairs who put the workshops together as well as Therese, Areti and Diane.
Best wishes for what should be an enjoyable and fulfilling 2 days. Yours sincerely,
Professor Ken O’Byrne
brisbane diamantina health partners
Brisbane Cancer Conference | December 17 – 18, 2015
Preliminary Program
9:00 – 12:00pm Rooms available for meetings
12:30 – 1:30pm Immunotherapy: translation of science into clinical care Chair: Ken O’Byrne
The science – Paul MainwaringThe clinic – Euan Walpole
Symposium supported by Merck, Sharp and Dohme
Registration desk opens at 1pm
1:30 – 2:00pm Refreshments served
2:00 – 3:00pm Plenary lectures (1) Chair: John Prins
Overview of Genomics in Brisbane – Lyn GriffithsProteomics – Michelle Hill DNA repair – Derek Richard
3:00 – 4:00pm Plenary Lectures (2) Chair: Janet Hardy
Patient outcomes research – Patsy YatesExercise in cancer care; the evidence – Sandra HayesMindfulness and meditation in cancer care – Geoff Hawson
4:00 – 4:30pm Break
4:30 – 6:30pm Workshops
Imaging – Room A1 Chairs: Liz Kenny, Graham Galloway
• Cell imaging – Anthony Davies• Understanding prostate cancer and how it informs imaging and therapy – Pamela Russell• Pre–clinical imaging – Brian Tse• Imaging turns to therapy – Adrian Fuchs• Improving the targeting – Les Thompson• Molecular imaging meets morphology – Stephen Rose• From diagnostic imaging to DNA: reverse translation in the development of imaging biomarkers
– Ken Miles
Genomics – Room A2 Chair: John Pearson
• Whole Genome Sequencing in the Clinic – Deon Venter• Genomics at Pathology Queensland – Valentine Hyland• Title TBA – James Harroway• Genetic Health Queensland’s approach to Familial Cancer – Helen Marfan• Novel diagnostics in breast cancer – Cameron Snell• Genomics in lymph nodes – Farzad Bashirzadeh
Thursday 17 December 2015
Brisbane Convention and Exhibition Centre
Preliminary Program
Thursday 17 December 20154:30 – 6:30pm Workshops continued
Clinical trials support teams – Room B1 Chairs: Adam Stoneley, Dan McKavanagh
• Raising Awareness of Clinical Trials – Luke Edington• Professional Development for Clinical Research: ARCS Australia – Sue Mason• Pharmacist Prescribing Research – A Potential Opportunity for Cancer Services? – Andrew Hale• The use of a brochure to enable CAM–with–chemotherapy patient education – Peter Smith• Patient medication access programs for the treatment of cancer: patterns of use and patients
outcomes at a tertiary metropolitan hospital – Christine Carrington• Administration burden for Conducting Research – Jennifer Larsen• Reducing Clinical Trial Administration – Allan Bukuya• Big Data and the EHR – Ian McPherson
Conclusions
Palliative care – Room B2 Chair: Clive Eakin
• Centre for Research excellence in End of Life Care – Patsy Yates• Working with primary care to improve outcomes at the end of life – Geoff Mitchell• The moralities of informal care of the dying – Phillip Good• Integrated care in a major cancer centre – Petra Vayne–Bossert • Communication in paediatric palliative care – Anthony Herbert• Targeted versus single agent therapy for nausea not related to cancer treatment – Janet Hardy
Nursing workshop: patient outcomes research – Room B3 Chair: Ray Chan
• Strategies translating research into practice – Leanne Stone• Underlying mechanisms of cancer–related symptoms – Kim Alexander• Evaluating clinical interventions (CASCADE trial) – Nicole Gavin• Evaluating health service interventions: Prostate cancer nurse trial – (TBC)• Discussion and ideas for research
6:30pm Welcome receptionFood, Drink, Music and Fun!
Brisbane Cancer Conference | December 17 – 18, 2015
Preliminary Program
7:30am Registration desk opens
8:00 – 10:00am Plenary lectures Chair: Frank Gannon
Overcoming obstacles to biobanking; a personal story – Sarah OlsenApplication of multiomics – Sunil LakhaniImaging tumour biology – Carolyn MountfordBone marrow transplantation – Geoff Hill Advances in radiotherapy – Mark PinkhamTargeted therapies in malignant disease – Kenneth O’ByrneThe challenge of novel therapy access in children – Ross PinkertonImmunotherapy, now and the future – Riccardo Dolcetti
10:00 – 10:30am Break
10:30am – 12:00pm Workshops
Novel immunotherapy targets – Room A1 Chair: Ian Frazer
• Targeting CD96/TIGIT in malignant disease – Stephen Blake• Genetic engineering of T-cells – Siok Tey• PDL2 in cancer: a biomarker and potential immune enhancement strategy – Michelle Wykes• EGFR and HER2 as immunotherapy targets – Fiona Simpson• Skin cancer immunology – James wells • Immunotherapy for blood cancers – Steve Mattarollo
Gynae-oncology – Room A2 Chairs: Pam Pollock, Jim Coward, Penny Webb, Annette Shewan
Workshop title:“Standing on the shoulders of giants – accelerating translational gynaecological cancer research via the Queensland Centre for Gynaecological Cancer (QCGC)”
• The QCGC cohort: mining for gold to build for better outcomes for women with gynaecological malignancies – Alex Crandon
• The QCGC FEMME trial - Prof Monika Janda - and the planned translational studies – Dr Eva Baxter
• The Mater Ovarian Cancer Research Collaborative (MOCRC): from baby steps to current standing…and beyond! – John Hooper
• Current status of the Australian National Endometrial Cancer Study (ANECS) – a resource of genetic, molecular, epidemiological and clinical data and associated biospecimens – Amanda Spurdle
• Where to for wellness and Survivorship for Gynae Cancer Patients – Sandi Hayes
Thoracic malignancies – Room B1 Chair: TBC
• Overview on clinical trials in Queensland – Abhishek Joshi• Automated evaluation of nodules – Alex Ritchie • EBUS and EUS core biopsies: a reality? – Michael Fanning• Interventional radiology – John Coucher• Optimal surgical staging for clinical trials – Chris Cole • Advances in radiation oncology – Margot Lehmann • Microwave ablation alternative alternatives – Nick Brown• Genomics of asbestos cancers – Nic Waddell • Thoracic malignancies; Nutritional issues – Laisa Teleni
Friday 18 December 2015
Brisbane Convention and Exhibition Centre
Preliminary Program
10:30am – 12:00pm Workshops continued
Brain tumours – Room B2 Chairs: Zarnie Lwin, Matt Foote, Sarah Olsen
• 5-ALA fluorescence guided surgery for glioma – Lindy Jefree• Gamma knife application for brain tumours – Matthew Foote• Activation of the NFIB pathway for glioblastoma therapy – Linda Richards & Jens Bunt • Neuro-oncology research, a care co-ordinator’s view – Vivien Biggs• Neurooncology research, a trial co-ordinator’s view – Annette Cubitt• Management of CNS tumours in Australia for AYA – Wayne Nichols• Supportive Care Interventions – Danette Langbecker
GU malignancies – Room B3 Chairs: Elizabeth Williams, Pamela Russell, Peter Heathcote
• Molecular imaging to differentiate small renal masses – Glenda Gobe• Modeling osteosclerotic metastatic ex-vivo – Elizabeth Williams• Advances in imaging prostate cancer – Sonya Greenslade• Issues for local control in PSMA positive oligometastatic prostate cancer
> Surgery – Geoff Coughlin > Radiotherapy – Kumar Gogna
• Novel systemic therapies for GU cancer – TBC• TrueNTH Survivorship Program – Patsy Yates
Hepatocellular Cancer – Room P6 (Plaza level) Chairs: Elizabeth Powell, Paul Clark
10:30 – 10:35 Welcome; Liver cancer – current problems, new strategies?
10:35 – 10:45 Hepatocellular cancer – race, remoteness and disadvantage – Paul Clark
10:45 – 10:55 Prevention and surveillance – can we do better? – Richard Skoien
10:55 – 11:05 Targeted HCC therapy – Jason Steel
11:05 – 11:15 Supportive care needs of people with liver cancer and cirrhosis – Patricia Valery
Panel Discussion Chairs: Graeme Macdonald, Andrew Clouston
12:00 – 12:30pm Lunch
Friday 18 December 2015
Brisbane Cancer Conference | December 17 – 18, 2015
Preliminary Program
12:30 – 2pm Plenary Lectures: Lectures celebrating cancer research success in Brisbane Chairs: Ross Young, Stephen Ayre
Vaccines in Oncology – Ian FrazerAdvances in Lung Cancer – Kwun FongPancreatic Cancer genomics – Nic WaddellBiomarkers in Lymphoma – Maher GandhiIntegration of genomics with oesophageal cancer care – Andrew BarbourFunctional outcomes in cancer care – Bena Cartmill
2:00 – 2:30pm Break
2:30 – 4:00pm Workshops
Haematology – Room A1 Chair: Andrew Perkins
• Paediatric Leukaemia: Translational Research Opportunities & Challenges – Andrew Moore• Exploring T cell tolerance with transcriptomics – Raymond Steptoe• The role of recipient macrophages in bone marrow recovery post-transplant – Liza Raggatt• The hypoxia sensing system in normal and malignant haematopoiesis – Jean Pierre Levesque• Identifying clinical indicators of deteriorating and terminal illness in haematology patients
– Elise Button• Azacitidine and bortezomib in the home programs – Leanne Stone
Breast Cancer – Room A2 Chairs: Rik Thompson, Kate Cuff, Marie Burke
• Lack of evidence for known human viral transcripts within breast cancer tissue – Orla Gannon• Precision Medicine in breast cancer: from molecular profiles to targeted therapies
– Fares Al-Ejeh• Targeted therapies in Breast Cancer – Natasha Woodward• Circulating tumour cells – Rik Thompson• A national infrastructure for the development of tissue resources in metastatic disease:
‘BROCADE’ – Amy McCart Reed• Identifying novel breast cancer genes responsible for the BRCAness phenotype – Eloise Dray• Young Women’s Wellness Program – Amanda McGuire
Melanoma and skin cancer – Room B1 Chairs: Peter Soyer, Euan Walpole
• Characterisation of naevus cells in culture – Stephen Ainger• The prognostic and predictive value of melanoma-related microRNAs using tissue and serum
– Mitchell Stark• Checkpoint defects in melanoma – Brian Gabrielli• Targeting RANK Ligand pathways in combination immunotherapy – Elizabeth Aherne• Rationalising the management of cutaneous melanoma in transit – Tavis Read• Progress in immunotherapy for metastatic melanoma – Euan Walpole
Friday 18 December 2015
Brisbane Convention and Exhibition Centre
Preliminary Program
Friday 18 December 20152:30 – 4:00pm Workshops continued
Head and Neck cancer – Room B2 Chairs: Sandro Porceddu, Chris Perry
• Hypoxia in Head and Neck Cancer – Ben Chua • Immunotherapy in Head and Neck Cancer – Jim Coward• Utility of Trans Oral Robotic Surgery – Sam Douthwaite• Using telepractice to enhance allied health management of HNC during (chemo)radiotherapy
– Laurelie Wall• Living with dysphagia following head and neck cancer treatment: What we can learn from our
patients and families – Rebecca Nund• ENHANCES Survivorship Program – Jane Turner • Discourse analysis of head and neck cancer – Carla Thamm
Colorectal cancer – Room B3 Chairs: Nick Lutton, Warren Joubert
• Pathological changes in colon carcinogenesis – Mark Bettingham• Molecular changes in colon carcinogenesis – Vicki Whitehall • Patient derived xenografts – John Hooper• Colon cancer clinical trials – Melissa Eastgate • Update on neuroendocrine tumour research – David Wyld• Overview of recent surgical trials: implications for treatment and research – Tim Slack
4:00pm Plenary Lecture Chairs: David Siddle, David Theile
Research Excellence, the key to success in cancer care – Mark Smithers
5:00pm Closing remarks – Ken O’Byrne
Brisbane Cancer Conference | December 17 – 18, 2015
Venue Floor Plans
Arbour LevelBCEC on Grey Street
Lower Level of BoulevardAuditorium
Speakers Presentation Centre
Lift
Backstage
ChangeRoom
GreenRoom
ArbourSpeakers Lounge
Lobby
Arbour Boardroom
Lift
Lift
Arbour Foyer
Lift
BarArbour LoungeA2
Lift
Retail Mezzanine A1
Arbour Level Rooms Theatre Classroom Banquet Cocktail Metres2
Arbour Lounge - - - 150 190
Meeting Room A1 50 30 20 60 70
Meeting Room A2 120 70 80 120 120
Arbour Speakers Presentation Centre - - - - 70
Arbour Boardroom - - 16 - 38
Grey StMerivale St
Glenelg St
Melbourne StMezzanine Level
Foyer Level Ground Level
Arbour Level
Boulevard Level
Plaza Level(Grey Street)
(Grey Street)
(Grey Street)
(Grey Street)
(Grey Street)
Sky Level(Grey Street)
Plaza Level(Merivale Street)
(Merivale Street)
(Merivale Street)
Concord Level
Important notes• Theatre and classroom capacities include staging, for speaker appropriate to the size of the room.• Banquet and cocktail capacities are the comfortable maximums for each room. Staging and/or dance floors have not been incorporated and will reduce these capacities.• Information accurate at time of printing.
more personal - more choice
31.7.2012 www.bcec.com.au
Boulevard LevelBCEC on Grey Street
BoulevardAuditorium
Boulevard Auditorium Foyer
BoulevardRoom
B1B2B3Lobby
Lift
Lift
Lift
Boulevard Room Foyer
Boulevard North Terrace
Boulevard Central TerraceRegistration
Bar
LoadingGreen Room
Bar
Boulevard Level Rooms Theatre Classroom Banquet Cocktail Metres2
Boulevard Auditorium 430 - - - -
Meeting Room B1 130 75 80 110 113
Meeting Room B2 130 75 80 110 113
Meeting Room B3 130 75 80 110 113
Meeting Room B1 & B2 270 160 180 240 231
Meeting Room B2 & B3 270 160 180 240 231
Meeting Rooms B1, B2 & B3 450 260 280 350 345
Boulevard Room 600 350 390 600 530
Grey StMerivale St
Glenelg St
Melbourne StMezzanine Level
Foyer Level Ground Level
Arbour Level
Boulevard Level
Plaza Level(Grey Street)
(Grey Street)
(Grey Street)
(Grey Street)
(Grey Street)
Sky Level(Grey Street)
Plaza Level(Merivale Street)
(Merivale Street)
(Merivale Street)
Concord Level
Important notes• Theatre and classroom capacities include staging, for speaker appropriate to the size of the room.• Banquet and cocktail capacities are the comfortable maximums for each room. Staging and/or dance floors have not been incorporated and will reduce these capacities.• Information accurate at time of printing.
more personal - more choice
31.7.2012 www.bcec.com.au
Boulevard Level
Arbour LevelBCEC on Grey Street
Lower Level of BoulevardAuditorium
Speakers Presentation Centre
Lift
Backstage
ChangeRoom
GreenRoom
ArbourSpeakers Lounge
Lobby
Arbour Boardroom
Lift
Lift
Arbour Foyer
Lift
BarArbour LoungeA2
Lift
Retail Mezzanine A1
Arbour Level Rooms Theatre Classroom Banquet Cocktail Metres2
Arbour Lounge - - - 150 190
Meeting Room A1 50 30 20 60 70
Meeting Room A2 120 70 80 120 120
Arbour Speakers Presentation Centre - - - - 70
Arbour Boardroom - - 16 - 38
Grey StMerivale St
Glenelg St
Melbourne StMezzanine Level
Foyer Level Ground Level
Arbour Level
Boulevard Level
Plaza Level(Grey Street)
(Grey Street)
(Grey Street)
(Grey Street)
(Grey Street)
Sky Level(Grey Street)
Plaza Level(Merivale Street)
(Merivale Street)
(Merivale Street)
Concord Level
Important notes• Theatre and classroom capacities include staging, for speaker appropriate to the size of the room.• Banquet and cocktail capacities are the comfortable maximums for each room. Staging and/or dance floors have not been incorporated and will reduce these capacities.• Information accurate at time of printing.
more personal - more choice
31.7.2012 www.bcec.com.au
Arbour Level
Brisbane Convention and Exhibition Centre
Sponsor Floor Plan
Astellas 9
Astrazeneca 7
BMS 5
4
Cancer Council Queensland 6
Celgene 13
Illumina 15
Ipsen 3
Janssen 1
Lilly Oncology 2
Merck 11
MSD 8
Novartis 14
Pfizer 12
Roche 10
Thursday, 17 December – Friday 18 December 2015Brisbane Convention and Exhibition Centre
Brisbane Cancer Conference
info@diamantina.org.aubrisbanediamantina.com
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