как это работает4

A T

A T

A T

G C

G C

GC

GC

GC

GC

T A

T A

T A

G C

T A

5`

5`

3`

3`

OH2C

O

P-O

O OH

P-O

O O

OH2CO

N

N

N

N

N

H

H

N

H3C

N

O

O

H

P

O-

OO

OH2C

O

OH

OH2C

O

HON

H

H

N

N

N

N

O

H N

O

N

H

H

N

P

O-

OHO

N

N

NH2

O

N

N

N

N

NH2

N

N O

H

O

H3C

N

H

H

N

N

N

N

O

H

OH2CO

A T

A T

A T

G C

G C

GC

GC

GC

GC

T A

T A

T A

G C

T A

OH2C

O

P-O

O OH

P-O

O O

OH2CO

P

O-

OO

OH2C

O

OH

OH2C

O

HO

P

O-

OHO

P-O

O O

OH2CO

P-O

O O

OH2CO

OH2C

O

OH2C

O

P

O-

OO

P

O-

OO

P-O

O O

5`

5`

3`

3`

5`

5`

5`

5`

3`

3`

3`

3`A

C

T

G

A CT G

A TG C

N

N

NH2

O

N

N

N

N

NH2

N

N O

H

O

H3C

N

H

H

N

N

N

N

O

H

OH2CO

A T

A T

A T

G C

G C

GC

GC

GC

GC

T A

T A

T A P-O

O O

5`

5`

3`

3`

A

A

A

G

G

C

C

C

U

U

U

G

U

5`

3`

N

N

NH2

O

N

N

N

N

NH2

N

H

H

N

N

N

N

O

H

OH2CO

OH

P-O

O O

N

N O

H

O

N

N

NH2

O

N

N

N

N

NH2

N

N O

H

O

H3C

N

H

H

N

N

N

N

O

H

OH2CO

P-O

O O

N

N

NH2

O

N

N

N

N

NH2

N

H

H

N

N

N

N

O

H

OH2CO

OH

P-O

O O

N

N O

H

O

OH2C

O

P-O

O OH

P-O

O O

OH2CO

P

O-

OO

OH2C

O

OH

OH2C

O

HO

P

O-

OHO

P-O

O O

OH2CO

P-O

O O

OH2CO

OH2C

O

OH2C

O

P

O-

OO

P

O-

OO

5`

5`

3`

3`

A

C

TG

P-O

O OH

P-O

O O

OH2CO

OH

OH2C

O

HO OHN

H

H

N

N

N

N

O

H

N

N

O

O

H5`

3`

A

C

UG

A T

A T

A T

G C

G C

GC

GC

GC

GC

T A

T A

T A

5`

5`

3`

3`N

H

H

N

N

N

N

O

HN

N O

H

O

H3CN

N

N

N

NH2

N

N

NH2

O

AGGACTCCACTT

TTCACCTCAGGA

A T

A T

A T

G CG C

GC

GCGC

GC

T A

T AT A

C

UA T

A T

A T

G C

GC

GC

GC

T A

T A

5`

5`

3`

3`

5`

3`

U

G

A

G

G

U

A

N

N

NH2

O

N

N

N

N

NH2

N

N O

H

O

H3C

N

H

H

N

N

N

N

O

H

C

T

A

G

C

T A G

C

T

AG

C

T

A

GC T A GC T

A

G

C

A

GC

T

A

G

C

T

A

G

C TA GC

T

A

G

C

T A

G

C

A

G

C

T

A

G

C

T

A

G

C

T

A

G

C T

AGC

T

A GC

A

G

C

T AG

C

T

A GC T

A

GC T A G

C

T A

G

C

A

GC

T

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T

A G

C

T

A

G

C

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A

G

C

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AG

C

A

C

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AG

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A G

C A

G

C

T A GC T

AG

C

GC

T

A

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A

TA

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GT

A

C

A

G

T

A

G TG

C

A

G

A GC A G C TA G

C

T

C

G

A

T C

T

G

C A

C

T

G

C

A G

C

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AG

C

T

A

G

AG

C

T AG C

A

G

C

A

G

C

T

G

C

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A GC T

A

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C

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A

G

C

A

C

T G

C

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G

C

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A

C

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AG

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A

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GC

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AG C

T

AG

C

TA

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AG

C

A

A

A

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CAC C ATC TTG AG CTG

C

T A G TA C

T

AG TT G C AC GAC AG CA GCA G AT

G

AG

C

1000x

1000x

10000x

x 10

1000x

1 2 3

H

CC

C C

N

N O

H3C

H

H

O

H CC

C C

N

N O

H3C

H

H

O

HCC

C C

N

N O

H3C

H

H

O

HCC

C C

N

N O

H3C

H

H

O

H

O

O

CC

C C

N

N O

3CH

H

H

O

H

31 2

N

H

H

N

N

N

N

O

H

N

N O

H

O

H3C

N

N

N

N

NH2

N

N

NH2

O

CC

C C

N

N O

H3C

H

H

O

H

CC

C C

N

N O

H3C

H

H

O

H

CC

C C

N

N O

H3C

H

H

O

H

CC

C C

N

N O

H3C

H

H

O

H

CC

C C

N

N O

H3C

H

H

O

H

29

Cu

79

Au

47

Ag

X

Z

Y

Z

X

Z

Y

X

Z

1

3

1

3 1

TERS

29

Cu

79

Au

47

Ag

TERS

1 2 3

79

Au47

Ag

X

Z

Y

D

B

E

A

C

F

G

H

D

B

E

A

C

F

G

H

1 2 3

1 2

3

4 5 6

45

6

A T

A T

A T

G C

G C

GC

GC

GC

GC

T A

T A

T A

5`

5`

3`

3`

C

C

C

C C

G

C

A G

C

AG

C A

G

AG

C

T AG C

A

C

A

C

T

A GC T

A

G

A

C

T

A

G

CA

C

T

G

C G

A

G

C

T

T

GC TG

C

AC

A

GC

T

T C

A

G

T

C

C

T G