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Disclaimer: All material in this ebook is provided for information only and may not
be construed as medical advice or instruction. No action or inaction should be taken
based solely on the contents of this ebook. Instead readers should consult their
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and well-being. Readers who fail to consult with appropriate health authorities
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omissions.
Stop AcidRefluxNow!
Revised October 2007
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Table of Contents
Introduction ________________________________________________________4
What are Acid Reflux, GERD and Heartburn? _______________________________ 4
What’s the Difference Between GER and GERD?____________________________ 7
Causes ________________________________________________________________ 7Being Overweight ____________________________________________________________8Pregnancy __________________________________________________________________9Hiatal Hernia ________________________________________________________________9Lower Esophageal Sphincter______________________________________________ 9Esophageal Contractions________________________________________________ 10Emptying of the Stomach_____________________________________________________10Genetics_____________________________________________________________ 10
Symptoms_____________________________________________________________ 10
The Impact of Acid Reflux, GERD and Heartburn _____________________13The Stressed _______________________________________________________________13Pregnant Women ___________________________________________________________13Over 50s ___________________________________________________________________14The Overweight _____________________________________________________________15Infants and Children _________________________________________________________15Symptoms indicative of Reflux Disease or GERD: _____________________________17
Medication Takers___________________________________________________________19Medications Used to Treat Asthma and Breathing Difficulties____________________20Medications Used to Treat Heart and Blood Pressure __________________________20Medications Used to Treat Arthritis and Inflammation __________________________20Medications Used to Treat Osteoporosis _____________________________________20Medications Used to Treat Anxiety, Insomnia, Depression, and Pain _____________21Medications Used to Treat Parkinson's Disease and Muscle Spasms ____________21Medications Used to Treat Cancer __________________________________________21Hormones _______________________________________________________________21
Complications _______________________________________________ 22
Anemia _______________________________________________________________ 22
Apnea ________________________________________________________________ 22
Asthma _______________________________________________________________ 22
Barrett's Esophagus ____________________________________________________ 23
Bleeding and Ulcers ____________________________________________________ 23
Coughing and Hoarseness ______________________________________________ 24
Eroded Dental Enamel __________________________________________________ 24
Esophageal Cancer_____________________________________________________ 24
Failure to Thrive________________________________________________________ 25
Fluid in the Sinuses and Middle Ears______________________________________ 25
Gagging and Choking___________________________________________________ 26
Inflammation and infection of the Lungs ___________________________________ 26
Inflammation of the Throat and Larynx ____________________________________ 26
Painful and Difficult Swallowing __________________________________________ 26
Sleep _________________________________________________________________ 27
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Diagnosing Acid Reflux, GERD and Heartburn _______________________28
Examination of the throat and larynx ______________________________________ 29
Endoscopy ___________________________________________________________ 259
Biopsy ________________________________________________________________ 29
Esophageal pH Probe___________________________________________________ 30
X-Rays________________________________________________________________ 30
Esophageal Acid Testing ________________________________________________ 30
Acid Perfusion Test_____________________________________________________ 32
Esophageal Motility Testing______________________________________________ 32
Gastric Emptying Studies________________________________________________ 32
Medications ___________________________________________________________ 34Antacids ___________________________________________________________________34Foaming Agents ____________________________________________________________35H2 Blockers_________________________________________________________________33Proton pump Inhibitors _______________________________________________________36Prokinetics _________________________________________________________________37
Surgery _______________________________________________________________ 37Fundoplication ______________________________________________________________36Potential Complications of Fundoplication ____________________________________39
Endoscopy _________________________________________________________________40
Lifestyle Changes ______________________________________________________ 41Eating Habits _______________________________________________________________41Smoking ___________________________________________________________________41Weight loss_________________________________________________________________41Alcohol ____________________________________________________________________42Relaxation__________________________________________________________________42Exercise ___________________________________________________________________42Dressing Sensibly ___________________________________________________________42Sleep ______________________________________________________________________43
Dealing With Stress_____________________________________________________ 43
Herbal Treatments______________________________________________________ 45
Digestive Enzymes _____________________________________________________ 49
Diet___________________________________________________________________ 50Food Table _________________________________________________________________53Recipes____________________________________________________________________55Breakfast ________________________________________________________________56Lunch ___________________________________________________________________57Main Courses ____________________________________________________________59Desserts_________________________________________________________________63
Pregnancy_____________________________________________________________ 67
Infancy________________________________________________________________ 69
Common Myths __________________________________________________ 71
GERD at a Glance ________________________________________________ 74
For More Information _____________________________________________ 77
Glossary __________________________________________________________79
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Introduction
What are Acid Reflux, GERD and Heartburn?
GERD, or gastro-esophageal reflux disease, is an alternative name for what
many people call acid reflux. It is a condition that occurs when your lower
esophageal sphincter doesn’t close properly and your stomach contents leak
back, or reflux, into your esophagus.
The lower esophageal sphincter, or LES, is a ring of muscle, which is at the
bottom of your esophagus - or gullet - that acts like a valve between your
esophagus and stomach. Your esophagus carries the food you eat from your
mouth to your stomach.
When refluxed stomach acid contacts the lining of your esophagus, it can
cause a burning feeling in your chest or throat known as heartburn. When this
fluid is tasted in the back of your mouth this is called acid indigestion. This
may inflame and damage the lining of your esophagus.
The regurgitated liquid usually contains acid and pepsin, an enzyme produced
in the stomach that begins the digestion of proteins. The refluxed liquid may
additionally contain bile that has backed-up into your stomach from your
duodenum, which is the first part of the small intestine that attaches to your
stomach. The acid is believed to be the most damaging part of the refluxed
liquid.
Heartburn usually feels like a burning pain in your chest, beginning behind
your breastbone and moving upward to your neck and throat. It can feel like
food is coming back into your mouth leaving an acidic or bitter taste. The
burning, pressure can last up to two hours, or longer and is often worse after
eating. Heartburn can also be caused by lying down or bending. The most
common remedy is to take an antacid that can help neutralize acid in the
stomach.
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Heartburn pain is sometimes mistaken for a heart attack, but there are a
number of differences. For example, a heart attack typically feels like your
chest is being squeezed or crushed with the pain extending up into the jaw
and back and can be accompanied by cold sweats. Exercise makes the chest
pain worse, whereas with heartburn the pain often gets worse with rest,
especially when lying down.
However, if you suspect a heart attack it’s important to seek medical attention
immediately.
Occasional heartburn is common, but this doesn’t necessarily mean that you
have GERD. If your heartburn occurs more than twice a week, a doctor will
often diagnose GERD, which can possibly lead to more serious health
problems.
Although heartburn is the most common symptom of GERD, you can have
GERD without having heartburn. Symptoms can include excessive clearing of
your throat; problems swallowing; the feeling that food is stuck in your throat;
a burning feeling in your mouth; or chest pain.
GERD may cause coughing, and other respiratory problems as well as
repeated vomiting in infants and children. Most infants grow out of GERD by
the time of their first birthday.
If you’ve been using antacids for over two weeks, you need to see your
medical practitioner. You may also need to visit a specialist - a
gastroenterologist— who treats diseases of the stomach and intestines.
Changes in your lifestyle and diet changes can help to relieve heartburn.
Some people who suffer from GERD also need medication, and surgery may
be a last resort solution.
No-one knows why some people who suffer from heartburn develop GERD.
Several factors are likely to be involved. GERD is a chronic condition, and
once it begins, it tends to last your whole life unless life style changes are
made. After medical treatment, the condition returns in most patients within a
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few months. Therefore, once treatment for GERD is started it usually needs to
be continued indefinitely unless it is managed through life style changes.
Reflux actually occurs in most individuals. The difference with GERD sufferers
is that reflux is experienced more frequently and as a result damage is often
caused to the esophagus.
During the day acid reflux can often be counteracted by the body’s natural
position and process. The refluxed liquid is more likely to flow back down into
your stomach. Also, while you are awake, you repeatedly swallow, whether or
not you have reflux. Each time you swallow refluxed liquid is carried back into
the stomach. The saliva glands in your mouth produce saliva, which contains
bicarbonate. This means that the bicarbonate-containing saliva that travels
down the esophagus neutralizes the small amount of acid that remains in your
esophagus. Because you swallow less when sleeping your saliva is reduced,
and reflux that occurs at night is more likely to cause acid to remain in the
esophagus longer, potentially causing damage.
Some people are more susceptible than others to GERD. For example, it can
be a serious problem during pregnancy. Higher hormone levels and the
growing fetus increasing pressure in the abdomen contribute towards this.
About twenty-five million adults suffer from heartburn daily. Twenty-five per
cent of pregnant women experience daily heartburn and more than half per
cent have occasional problems. Over sixty million Americans experience
heartburn at least once a month. Recent studies show that GERD in babies
and children is more common than was previously recognized and may
produce a variety of problems. In the following sections, we’ll look at GERD in
more detail, and the various options for managing this condition.
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What is the Difference Between GER and GERD?
The term reflux is an alternative way of referring to GER (Gastro Esophageal
Reflux). When someone is referred to as having GER, it means that they have
a benign condition in which they have frequent reflux episodes. This may also
be called "functional GER" and it doesn’t cause complications, lead to long
term problems, affect growth or development in babies or always require
medical attention. GER can range from reflux material in the esophagus to
spitting up and sometimes frequent projectile vomiting in babies. Projectile
vomiting alone is not a complication. GER is referred to as GERD when
complications arise. However, the terms are often used interchangeably. In
secondary GER, there is an underlying cause of the reflux episodes.
Examples of secondary GER are food allergies, metabolic disorders and
infections.
Silent GER refers to GER or GERD without any obvious or typical symptoms.
It means that someone isn't vomiting or appearing uncomfortable but is having
episodes of reflux. Some children swallow refluxed material back down
instead of throwing it up. This can be much more difficult to diagnose as the
most common symptoms aren’t present. Additionally, it can be more
damaging. Whether or not a child’s silent reflux needs to be treated depends
on the complications that arise from it.
Causes
No one knows why some people suffer with GERD and others don’t. However,
some factors that may contribute to GERD include:
� Drinking alcohol
� Being overweight
� Being pregnant
� Smoking
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Also, certain foods are associated with reflux occurrences including:
� Citrus fruits
� Chocolate
� Drinks with caffeine
� Fatty and fried foods
� Garlic and onions
� Mint flavorings
� Spicy foods
� Tomato-based foods
For a more comprehensive list please refer to the food table on page 50.
There are multiple causes, and different causes can be apparent in different
people or in the same individual at different times. A few people with GERD
produce abnormally large amounts of acid, however, this is not common.
Some factors that contribute towards GERD are hiatal hernias, lower
esophageal sphincter abnormalities, esophageal contractions, and slow
emptying of the stomach. Alcohol and smoking relax the LES, and therefore
can contribute to GERD as this allows the stomach contents to escape more
easily.
Being Overweight
People who are obese - in other words those who have a body mass index
greater than thirty - have been found to be almost three times more likely to
develop esophageal cancer than those with healthy body weight. (BMI is a
measure of a weight in relation to height.) Esophageal cancer can be a
complication of GERD.
Exactly how excess body weight increases the likelihood of GERD is unclear.
A possibility is that excessive weight in your abdomen compresses your
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stomach and raises the pressure inside, leading to reflux. In addition, obesity
can contribute towards the release of inflammatory substances that can raise
the risk of GERD. Diet plays a large role in the development of GERD and
fatty foods are high risk foods that commonly trigger acid reflux.
Pregnancy
Higher hormone levels in pregnancy cause reflux by lowering the pressure in
the LES as well as the growing fetus increases pressure in the abdomen. The
combination of these factors often increases reflux. Women with diseases that
weaken the esophageal muscles become more prone to develop GERD. It
usually begins in the first or second trimester of pregnancy and continues until
delivery. For many women, the heartburn is mild and intermittent; with others
it may be severe. The symptoms often disappear after delivery.
Hiatal Hernia
A hiatal hernia occurs when the upper part of the stomach bulges above your
diaphragm, the muscle wall that separates your stomach from your chest
cavity. The diaphragm helps the LES prevent acid from coming up into your
esophagus. With a hiatal hernia, it’s easier for acid to reflux. A hiatal hernia
can occur in people of any age, however it is more common in people over the
age of fifty. Sudden physical exertion, straining, coughing, or vomiting can
cause increased pressure in your abdomen resulting in hiatal hernia. Obesity
and pregnancy are also contributory factors. Hiatal hernias don’t always need
treatment.
Lower Esophageal Sphincter
Studies have shown that many GERD suffers have various abnormalities of
the LES. Common problems include an abnormally weak contraction of the
LES that reduces its ability to prevent reflux. Another is abnormal relaxations
of your LES, called transient LES relaxations. They don’t tend accompany
swallows, and can last for up to several minutes. These allow reflux to occur
more easily. They occur most commonly after meals when your stomach is
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distended with food and allow trapped air to escape in the form of burping. A
further problem is laxity of the LES. This allows easier opening of the LES and
a greater backward flow of acid.
Esophageal Contractions
Swallowing causes a wave of contraction of the esophageal muscles,
narrowing the inner cavity of the esophagus. This contraction begins in the
upper part of the esophagus and travels to the lower esophagus. It pushes
food and saliva down the esophagus into your stomach. When this contraction
is defective, refluxed acid is not pushed back into your stomach, therefore
staying in the esophagus for longer and increasing the risk of damage.
Emptying of the Stomach
Most reflux during the day occurs after meals. This reflux probably is due to
transient LES relaxations caused by your stomach being distended with food.
Some GERD sufferers have stomachs that empty abnormally slowly after a
meal. This prolongs the distension of their stomach with food after meals. The
slower emptying prolongs the time during which reflux is more likely to occur.
Genetics
It’s unclear whether GERD is inherited. The fact that members of the same
family often experience symptoms could be due to inherited genes, or it could
be due to their shared environment. Recent studies have shown that inherited
genes are likely to be an important cause of GERD, but non-genetic factors
are responsible for most cases.
GERD/Acid Reflux Symptoms
The main symptoms are recurring heartburn and the regurgitation of acid.
Some people suffer from GERD without heartburn. Instead, they feel chest
pain or hoarseness in the morning, or have trouble swallowing. It can feel like
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food is stuck in your throat, as if you are choking, or your throat is tight. GERD
may also cause bad breath and a dry cough. Some people also suffer from
nausea. In infants and children, it may cause episodes of vomiting, coughing,
and respiratory problems. Most babies grow out of GERD by their first
birthday.
Heartburn
Heartburn, also known as acid indigestion, is the most commonly experienced
symptom of GERD and often feels like a burning chest pain beginning behind
your breastbone and moving upwards to your neck and throat. Many sufferers
say it feels like food is coming back into their mouth leaving an acid or bitter
taste. Some people suffer a sharp or pressure-like pain rather than burning. It
can also extend to the back.
The pain of heartburn can last for two hours or more and is often more severe
after eating. It also tends to be worse at night or when lying down or bending
over. As acid reflux is more common after meals, heartburn is more likely to
occur after meals. Heartburn commonly strikes when you lie down because
acid that escapes into the esophagus returns to your stomach more slowly
without the aid of gravity. Relief can be obtained by standing up, propping
yourself up with pillows or by taking an antacid.
Episodes of heartburn tend to happen periodically. The episodes can be
frequent or severe for a several weeks or months, and then ease or disappear
for several weeks or months. However, heartburn tends to be a life-long
problem, and usually returns.
Regurgitation
Regurgitation is when refluxed liquid returns to the mouth. However, often
only small quantities of liquid reach your esophagus, with the majority of the
liquid remaining in your lower esophagus.
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Occasionally, larger quantities of liquid, sometimes containing food reach your
upper esophagus. When small amounts of refluxed liquid enter your throat,
your may experience an acid taste in your mouth. With larger quantities, you
may suddenly find your mouth filled with the liquid. Frequent or prolonged
regurgitation can lead to dental damage.
Nausea
Nausea is a less common symptom. However, some people suffer from
frequent or severe nausea, sometimes resulting in vomiting. In cases of
unexplained vomiting or nausea, GERD is usually one of the first conditions
suspected.
GERD can potentially lead to complications and cause conditions as serious
as cancer – more about these later on. If symptoms have persisted after two
weeks of using antacids, or you have unexplained nausea or vomiting, you
should see your doctor.
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The Impact of Acid Reflux, GERD and Heartburn
Who can Suffer From Acid Reflux?
The Stressed
About fifty-eight per cent of those who suffer frequent heartburn say that their
hectic lifestyle is a factor in their flare-ups. Over half of all heartburn sufferers
say that work-related stress increases their heartburn. Although stress hasn't
been directly linked to heartburn, it can lead to behavior that can triggers
heartburn.
During stressful times, people may not follow normal routines when it comes
to meals, exercise, and medication. By alleviating stress, you can make
stress-related heartburn less likely. Regular exercise helps to lower stress and
helps with digestion. Sleeping seven to eight hours each night will help to
keep your stress level lower as studies show that sleep-deprived people have
higher stress levels. Stress can also affect digestion by slowing it down. If
food lingers in the body too long it can enhance the effects of reflux.
Pregnant Women
Heartburn occurs in a quarter to half of all pregnant women. It tends to begin
in the first or second trimester and continues throughout the pregnancy. For
most women, the heartburn is usually mild and intermittent, but in some it can
be severe.
Complications of GERD in pregnant women are uncommon, however the
usual medications may not be safe in pregnancy, so alternative solutions may
need to be found.
The reason why acid reflux is common in expectant mothers is because the
LES can weaken during pregnancy. This is an effect of the change in levels of
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hormones (estrogen and progesterone) that forms part of pregnancy. This
weakness usually resolves itself after delivery.
It’s unknown if the contraction of the esophagus above the sphincter is
impaired in pregnancy by the baby and whether this is responsible for
delaying acid clearance from the esophagus back into the stomach. The
distortion of the organs in the abdomen along with increased abdominal
pressure caused by the growing fetus also acts to promote the reflux of acid.
Management of GERD during pregnancy involves many of the same
principles as treatment for non-pregnant individuals. Lifestyle changes are
particularly important. The head of the bed should be raised or six to eight
inches with wedge-shaped foam rubber pads used to elevate the upper body.
The wedges should extend all the way to the waist so that the entire chest is
elevated. Lying on the left side at night may also decrease acid reflux as this
promotes the clearance of acid from the stomach. Any specific foods that
aggravate heartburn should be avoided.
Over 50s
Up to twenty per cent of adults aged fifty-five to seventy-four suffer from
GERD. Reflux is more common in this age range because of the physiological
changes that time brings. The wave-like motions of the esophagus — that
push down food — may not be as powerful as they used to be. Aging can also
weaken the LES. Mature sufferers are also almost twice as likely to develop a
hiatal hernia, which can lead to acid reflux symptoms.
Other factors that can impair the LES include medications prescribed to
mature patients for other conditions, such as nitroglycerine (for angina),
calcium channel-blockers (for high blood pressure) and beta-agonists (for
asthma).
Erosive esophagitis (where the esophagus becomes inflamed, damaged and
bleeds) and other GERD complications occur more frequently in the over 50’s
age range. They frequently have impaired motility of the esophageal muscles,
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decreased saliva volume, hiatal hernias, take medications that may reduce
the strength of the sphincter, and are more likely to do less physical exercise.
The Overweight
People who are overweight (defined by a body mass index of 25 to 30) are
almost one and a half times as likely to develop GERD symptoms, while
people who are obese (a body mass index of 30+) are nearly twice as likely to
develop symptoms in comparison with those with a healthy body weight. Also,
obese people are almost three times more likely to develop esophageal
cancer than those with a healthy body weight. The risks increase with
increasing weight.
Popular opinion has associated heartburn with being overweight for a long
time, and most medical practitioners find this to be valid. Heartburn is often
caused by eating the wrong types of foods and can occur because of
overeating. Even small weight changes can increase the risk of heartburn.
Losing weight is a factor in managing heartburn, and as little as ten per cent
decrease in weight has been shown to improve heartburn symptoms.
However, weight loss does not guarantee symptoms will subside. Some
studies have shown that heartburn sufferers continue to experience symptoms
even after major weight loss. Therefore, weight loss alone may not be enough
to resolve symptoms for everyone.
Infants and Children
Reflux can occur when babies cough, cry, or strain. The majority of infants
with GERD are happy and healthy even if they spit up or vomit. More than half
of all babies experience reflux during their first three months of life.
An infant with reflux may experience:
� Constant or sudden crying or colic like symptoms
� Spitting
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� Vomiting
� Irritability
� Coughing
� Poor feeding
� Blood in their stools
� Irritability and pain
� Arching their necks and back during or after eating
� Poor sleep habits typically with frequent waking
� Spitting-up
� Wet burp or frequent hiccups
� Frequent ear infections or sinus congestion
An infant doesn’t need to exhibit all of these symptoms, in fact, only displaying
one of the above could mean they have reflux. This does not necessarily
mean that they need treatment. If your infant shows one or more symptoms,
but otherwise is happy and healthy, then some lifestyle modifications will help
until they outgrow it.
GERD is common and can be overlooked in children. It can cause vomiting as
well as coughing, and other respiratory problems. Children's immature
digestive systems are usually the cause, and most infants grow out of GERD.
Only a minority of infants suffers severe symptoms and most infants stop
spitting up between the ages of twelve to eighteen months.
Occasionally, babies have other symptoms that can cause concern including:
� Poor growth because of not holding down enough food
� Irritability
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� Refusing to feed due to pain
� Blood loss from acid burning the esophagus
� Breathing problems
The above problems can be caused by a number of disorders. Your doctor
needs to determine what is causing your child's symptoms. If the child is
healthy, happy, and growing well, tests or treatment may be unnecessary. Any
treatment depends on the infant's symptoms and age, and can include
changes in eating and sleeping habits. Medication may sometimes be an
option or even surgery in severe cases.
Symptoms indicative of Reflux Disease or GERD:
� Refusing food
� Accepting only a few bites of food despite being hungry
� Requiring constant small meals or liquid
� Food or oral aversions
� Anemia
� Excessive drooling
� Running nose
� Sinus infections
� Swallowing problems
� Gagging
� Choking
� A chronic, hoarse voice
� Frequent red and sore throat without an infection being present
� Apnea
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� Chronic ear infections
� Respiratory problems such as pneumonia, bronchitis, wheezing,
asthma, night-time cough, aspiration
� Gagging themselves with their fingers or fist (sign of esophagitis)
� Poor weight gain
� Weight loss
� Failure to thrive
� Dental enamel erosion
� Neck arching (Sandifer's syndrome)
� Bad breath
Because infant reflux is so common, reflux is often diagnosed simply by
child’s symptoms alone. Some doctors prefer to have tests done before
prescribing medication.
Some babies appear to have been outgrowing their reflux when their
symptoms return. Teething can irritate reflux as can colds, ‘flu, and other
common illnesses. At other times, reflux can get worse for a day or more with
no apparent reason.
Every baby is different, and it's difficult to pinpoint a single specific formula
that is the best to use when they have reflux. If your baby has a milk allergy
or sensitivity then giving a soy based or hypoallergenic formula may help their
reflux improve.
Hypoallergenic formulas are pre-digested (partially or completely) and they
tend to move through the stomach faster than standard formulas. Breast milk
is often the best option for reflux. Its proteins are more hypoallergenic than
those of formula and it's more easily digested.
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Babies with reflux are notorious for being poor sleepers. Propping them up
can be helpful, as can small frequent meals and not feeding them too close to
bedtime.
The treatment chosen depends on the infant's symptoms and age. Some
babies may not need treatment, because the condition often resolves by itself.
Healthy and happy babies may only need their food thickened with cereal and
to be kept upright after being fed. Overfeeding can worsen reflux, so your
doctor may suggest different ways of handling feeding. For example, smaller
quantities and more frequent feeding can help to decrease the chances of
regurgitation. If a food allergy is suspected, you may need to change your
baby's formula, or to modify your diet if you are breastfeeding. If a child isn’t
growing well, food with a higher calorie content or tube feeding may be
recommended.
Medication Takers
Heartburn can be brought on or worsened by many different medications. Let
your doctor know if you suffer from heartburn or if your heartburn worsens
when you begin a new medication.
It’s a good idea to keep a record of when you began to experience your
symptoms as well as when you started taking any new medication. This
applies whether it’s a prescription or non-prescription medication. If the
offending medication can’t be stopped, alternatives could be available. You
may be able to switch to another medication less likely to contribute towards
heartburn.
People who suffer from reflux should be aware of another pill-related problem.
If a pill became lodged in the esophagus, it could cause injury to its lining.
This can lead to ulcers and narrowing of the esophagus. Drugs most likely to
do this are certain antibiotics (particularly tetracycline); potassium
supplements; quinidine and alendronate. Anti-inflammatory agents can also
have this effect. It’s worth being careful with any pain medication. Always take
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a full glass of water to wash pills down and don’t lie down for half an hour to
an hour after taking them.
Medications Used to Treat Asthma and Breathing Difficulties
Theophylline, and other medication used for asthma and breathing difficulties,
can lead to a weakening of the LES, which makes it easier for stomach acid to
reflux into your esophagus. Some people taking these medications -
especially theophylline – suffer from heartburn. Using an inhaler may be less
problematic.
Medications Used to Treat Heart Conditions and Blood Pressure
Medications commonly used to treat heart conditions and high blood pressure,
for example, calcium channel blockers (diltiazem, nifedipine); beta-blockers
(propranolol, atenolol); alpha-blockers (prazosin); and nitrates (isosorbide
dinitrate, nitroglycerin) can also relax the LES increasing your risk of reflux.
Medications Used to Treat Arthritis and Inflammation
All non-steroidal anti-inflammatory drugs such as aspirin, ibuprofen, naproxen,
and those available without a prescription, may cause or worsen heartburn.
Cyclooxygenase-II inhibitors (celecoxib) are also associated with heartburn.
Low dosages of aspirin or NSAID aren’t likely to produce this side effect.
Medications Used to Treat Osteoporosis
Bisphosphonates, for example, alendronate (Fosamax) and risedronate
(Actonel), along with other medications used to treat osteoporosis, may injure
the lining of your esophagus and lead to heartburn. If you take these
medications, be sure to take them with a full glass of water and don’t lie down
for half an hour to an hour after swallowing them. Taking precautions reduces
the chance of these medications causing any injury to your esophagus.
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Medications Used to Treat Anxiety, Insomnia, Depression, and Pain
Some medications that act on the nervous system may contribute to
heartburn. Anti anxiety medications and agents used to treat insomnia, for
example, diazepam or lorazepam, antidepressants including the tricyclic
antidepressants such as amitriptyline, and narcotics such as morphine and
merpidine used to treat pain, may all cause or worsen your heartburn by
relaxing the LES.
Medications Used to Treat Parkinson's Disease and Muscle Spasms
Some anti-Parkinson medications containing levodopa and anti-spasmodics,
such as dicyclomine or glycopyrrolate, may increase reflux and heartburn by
causing your LES to relax when it needs to be closed.
Medications Used to Treat Cancer
Some drugs used to treat cancer may cause heartburn, indigestion, and
nausea. Those receiving cancer chemotherapy may require additional
medication to relieve heartburn and indigestion as well as medication to treat
nausea.
Hormones
Certain hormones, such as progesterone, a hormone contained in some birth
control pills, may contribute to heartburn symptoms by decreasing LES
pressure.
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Possible Complications
Anemia
Anemia can be caused by blood loss and is defined as a drop in hemoglobin
count. Reflux can lead to anemia by damaging your esophagus causing it to
bleed.
Apnea
Apnea refers to a pause of more than ten to twenty seconds during breathing.
People who have GERD are susceptible to apnea episodes. The exact cause
is not known however there are a number of theories. One theory is that sleep
apnea can change the pressure within the lungs and gastrointestinal systems,
possibly resulting in some of the stomach contents to be drawn up into the
esophagus. Another theory is that irritation of the esophagus due to reflux
could cause airway spasms that lead to sleep apnea.
Asthma
More than seventy-five per cent of people with asthma also have GERD or
reflux and asthma sufferers are twice as likely to have GERD as people
without asthma do.
When asthma is diagnosed, the possibility of reflux should be also be
investigated. Some sufferers don’t display any symptoms of reflux and are
referred to as having silent reflux. The only symptom may then become
asthma and the link between reflux and asthma may not be realized. This
means that their asthma can be difficult to control with normal medication.
One possibility as to why reflux makes asthma worse is that the acid refluxing
up your esophagus can enter the airways, especially when lying down. This
can cause your airways to narrow and create wheezing and shortness of
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breath. Over time, your airways can become damaged from the refluxing acid,
worsening asthma symptoms. Also, acid present in the lower part of your
esophagus can stimulate nerve endings, causing the muscle in your airways
to contract, narrowing breathing tubes and promoting asthma symptoms.
Some indications that asthma may be caused by reflux are:
� Asthma symptoms get worse after eating, particularly after eating high
fat foods
� Asthma like symptoms appear with any other typical or atypical
symptoms of reflux
� A persistent cough, which is worse when you lie down
Barrett's Esophagus
Long-standing or acute GERD can cause changes in the cells that line your
esophagus. These cells become pre-cancerous, and, may develop into
cancerous cells. This condition is called Barrett's esophagus, which occurs in
about ten per cent of acid reflux sufferers.
Barrett's esophagus can be diagnosed through an endoscopy and confirmed
by a biopsy. If you have this condition, you are advised to have occassional
surveillance endoscopies, to detect any pre-cancerous changes so that
cancer-preventing treatment can be started. Early treatment and prevention of
GERD prevents the progression of Barrett's esophagus to cancer. Newer
experimental techniques that destroy the Barrett's cells may also prevent the
progression to cancer. Thankfully, only a minority of those with Barrett’s
esophagus go onto develop cancer. The standard treatment for early cancers
in this case is surgical removal of a portion of your esophagus.
Bleeding and Ulcers
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Liquid refluxing from your stomach into your esophagus can damage the cells
lining your esophagus. An ulcer occurs when the lining breaks down and
inflammation and bleeding starts. Ulcers, and the accompanying inflammation
they cause, may erode into your esophageal blood vessels and cause
bleeding in your esophagus. Sometimes the bleeding is severe and requires
blood transfusions and surgical treatment.
You should seek immediate medical attention if you start coughing up or
vomiting blood or your stools take on a black, tarry appearance.
Coughing and Hoarseness
GERD is a common cause of unexplained coughing. In the same way that
acid refluxed from the stomach can damage your esophagus and lungs, it can
also damage your throat and vocal cords. Sometimes, this might be the only
symptom of GERD, which makes it more difficult to diagnose.
There are a number of nerves in your lower esophagus. Some of these nerves
are stimulated by refluxed acid resulting in heartburn. Other nerves don’t lead
to heartburn, rather they stimulate yet more nerves that provoke coughing.
This means that refluxed liquid can cause coughing without ever reaching
your throat.
Eroded Dental Enamel
Some GERD / Acid Reflux sufferers experience regurgitation. This can be just
liquid or liquid and food. Occasionally this can reach the mouth and when
stomach acid that enters your mouth, it can erode your teeth, just as it does
your esophagus, throat and vocal cords.
Esophageal Cancer
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The type of cancer associated with Barrett's esophagus is increasing in
frequency. Twelve to eighteen thousand new cases of Esophageal cancer are
diagnosed per year in the US.
One type of esophageal cancer, adenocarcinoma, accounts one-third to one-
half of esophageal cancers and is mainly found in Caucasian men.
Adenocarcinoma has been increasing steadily in the US and Western Europe.
It has been estimated that Barrett’s esophagus might be responsible for half of
all adenocarcinomas. However, adenocarcinoma can occur without the
changes of Barrett's esophagus.
Failure to Thrive
Newborns and young babies are expected to grow at a steady and predictable
rate, more rapidly than when they get older. Sometimes babies don’t gain
weight at an acceptable or safe rate and fall below the acceptable low end of
the scale. These babies are diagnosed as having failure to thrive.
Failure to thrive can have many different causes. GERD can cause failure to
thrive in a few ways. Frequent or constant vomiting makes weight gain, or
maintaining current weight, difficult or impossible. Even without vomiting,
some babies begin to associate food with pain and unpleasantness and
develop a dislike of eating. Occasionally, some children are so fearful of food
that only tube feeding can provide them with nourishment.
Fluid in the Sinuses and Middle Ears
Refluxed liquid that enters your upper throat can inflame your adenoids
causing them to swell. Swollen adenoids can block the passages from your
sinuses and Eustachian tubes (middle ear). When your sinuses and middle
ears are closed off from your nasal passages by your adenoids swelling, fluid
accumulates in them. This accumulation can lead to discomfort in your
sinuses and ears. Because the adenoids are more prominent in young
children, this is usually seen in children and not adults.
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Gagging and Choking
Babies and children with GERD seem to have a stronger gag reflex than other
children and they may frequently gag and choke on their food. They may also
gag and choke for no apparent reason, probably from refluxed material
coming part of the way up.
Inflammation and infection of the Lungs
Refluxed liquid can enter your lungs, called aspiration, which often results in
coughing and choking. Aspiration, however, can occur without producing
these symptoms. It can lead to infection of your lungs resulting in pneumonia.
This sort of pneumonia is serious and requires immediate treatment.
When aspiration is unaccompanied by symptoms, it can result in a slow,
progressive scarring of your lungs, which may be observed on chest x-rays.
It’s more likely to occur at night, as that is when the bodily processes that
protect against reflux and the coughing reflex are not active.
Inflammation of the Throat and Larynx
If refluxed liquid gets past your upper esophageal sphincter it can enter your
throat and even your voice box. The resulting inflammation can lead to a sore
throat and hoarseness.
Painful and Difficult Swallowing
Scars from tissue damage can narrow your esophagus and make swallowing
difficult. This is called a stricture. The scar tissue is thicker than the normal
lining of the esophagus causing a narrowing of the esophagus that can
prevent food and even liquids from passing through. Strictures can be
surgically corrected.
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Sleep
Reflux commonly impacts on the quality of sleep with many sufferers
experiencing their worst symptoms when lying down. Some sufferers, who
have respiratory problems worsened by acid reflux, may not show heartburn
symptoms.
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Diagnosing Acid Reflux, GERD and Heartburn
The usual way that GERD is diagnosed is by its characteristic symptom -
heartburn. To confirm a diagnosis, doctors commonly treat patients with
medications to suppress the stomach’s acid production. If heartburn is
diminished to a large extent, the diagnosis is confirmed.
There are problems with this approach because it does not include diagnostic
tests. Patients who have conditions that can mimic GERD – for example,
duodenal or gastric ulcers - may also respond to this treatment. If the doctor
assumes that the problem is GERD, they won’t look for the cause of the ulcer
disease.
An infection called Helicobacter pylori, or non-steroidal anti-inflammatory
drugs (ibuprofen), can also cause ulcers. These conditions would be treated
differently from GERD. There is also a placebo effect, which means that some
patients will respond to any treatment. This means that those who whose
symptoms are caused by something other than GERD (or ulcers) can feel a
decrease in symptoms after receiving treatment for GERD. These patients
then will be treated for GERD, even though they don’t have GERD and the
true cause of their symptoms won’t be pursued any further.
Typically, the first test done to diagnose reflux is not always the most reliable.
Negative results are common with children who do have reflux. This is
because the child needs to actually reflux during the test to produce a positive
result. The test is more valuable for determining anatomic abnormalities within
the digestive system.
If your heartburn does not improve with changes in lifestyle or drug treatment,
you may need additional tests.
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Examination of the throat and larynx
Sufferers with symptoms of cough, hoarseness, or sore throat, often visit an
ear, nose, and throat (ENT) specialist. The specialist frequently finds signs of
throat or larynx inflammation. Although diseases of your throat or larynx are
usually the cause of the inflammation, sometimes it can be due to GERD.
Therefore, acid-suppressing treatments are generally tried to confirm the
diagnosis.
Endoscopy
After a spray to numb your throat, a small flexible tube with a tiny camera
(called an endoscope) is inserted through your mouth and then down into your
esophagus and stomach. This is used to examine the lining of your stomach,
esophagus, and part of your small intestine. Most patients with symptoms of
reflux have a normal looking esophagus, and therefore endoscopy won’t help
in the diagnosis of GERD. If the procedure reveals injury to your esophagus,
no other tests are usually needed. Endoscopy will identify several of GERD’s
complications, including, ulcers, strictures, and Barrett's esophagus. Other
problems that may be causing similar symptoms to GERD can also be
diagnosed.
Biopsy
Biopsies can be painlessly obtained during an endoscopy. A biopsy is a small
sample of tissue that is extracted and then examined with a microscope for
signs of inflammation and other problems. A biopsy can reveal acid reflux
damage and rule out other problems if no infecting organisms or abnormal
growths are present. Biopsies are the way to diagnose the cellular changes of
Barrett's esophagus.
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Esophageal pH Probe
This method is often used when diagnosing infants. A light, thin wire with an
acid sensor at its tip is inserted through your nose and into the lower part of
your esophagus. The probe is used to detect and record how much stomach
acid comes back up into your esophagus. It can also tell if acid is in the
esophagus when a child has symptoms such as crying, arching their back, or
coughing.
X-Rays
Before endoscopy was introduced, an x-ray of the esophagus was the only
means available of diagnosing GERD. Barium solution – a white, chalky liquid
- is swallowed and a series of fluoroscopic x-rays taken at intervals over about
fifteen to twenty minutes. The barium highlights, or outlines, your esophagus,
your throat and your upper intestines, allowing the doctor to view food as it
travels down your esophagus, into your stomach and into the first part of your
small intestines. A problem with this method is that it is an insensitive test. In
other words, it fails to find signs of GERD in many patients because they had
little or no damage to the lining of their esophagus. X-rays are only able to
show some complications of GERD, such as ulcers and strictures. They are
most useful when evaluating complications.
Esophageal Acid Testing
To show whether acid is present in the esophagus and for how long a twenty-
four hour esophageal ph test. (Ph is how the amount of acidity is expressed)
is carried out.
A small tube (catheter) is passed through your nose and positioned in your
esophagus. It has a sensor to sense acid on its tip. The other end of the
catheter exits from your nose, wraps back over your ear, and travels down to
your waist, where it is attached to a recorder. Whenever acid refluxes back
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into your esophagus from your stomach, it stimulates the sensor. The recorder
then records the episode of reflux. After twenty to twenty-four hours, the
catheter is removed and the record analyzed. While the testing is being done,
you record each time you experience symptoms. It can then be worked out
whether acid reflux occurred at the same time that the symptoms were
present.
There are problems with this method. It is not enough alone to confirm the
presence of GERD. Ph testing is useful in managing GERD. The test can help
determine why symptoms do not respond to treatment. If testing reveals
substantial reflux while medication continues, then the treatment is ineffective
and needs to be changed. If testing reveals good acid suppression with
minimal reflux of acid, a diagnosis of GERD may be incorrect and other
causes for the symptoms can be considered. If reflux occurs at the same time
as the symptoms, then it is likely to be the cause of those symptoms.
A relatively new method for prolonged measurement - over forty-eight hours -
of acid exposure in your esophagus uses a small, wireless capsule attached
to your esophagus just above your LES. The capsule is passed to your lower
esophagus by a tube inserted through either your mouth or nose. After the
capsule is attached to your esophagus, the tube is removed.
The capsule measures acid refluxing into your esophagus and transmits its
information to a receiver worn at your waist. The capsule falls off the
esophagus after three to five days and is passed in a stool. The advantage of
this is that there is no discomfort or unsightliness from a catheter passing
through your throat and nose. However, sometimes the capsule does not
attach, or falls off prematurely. There may be periods when the receiver
doesn’t receive signals, and some information may be lost. Sometimes, there
is pain swallowing after the capsule has been placed.
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Acid Perfusion Test
The acid perfusion – Bernstein - test is used to see if chest pain is caused by
acid reflux. A catheter is passed through one nostril, down the back of your
throat, and into the middle of your esophagus. A diluted acid solution and a
salt solution are alternately poured through the catheter into your esophagus.
If the acid provokes the pain and the salt solution produces no pain, it’s likely
that your pain is caused by acid reflux. This test is only used rarely.
Esophageal Motility Testing
This determines how well the muscles of your esophagus are working. A
catheter is passed through one of your nostrils, down the back of your throat,
and into your esophagus. The catheter has sensors that detect pressure.
When the muscle of your esophagus contract pressure is generated in your
esophagus and detected by the catheter. The end of the catheter is attached
to a recorder. During the test, the pressure at rest and the relaxation of your
lower esophageal sphincter are evaluated. Sips of water are swallowed to
evaluate the contractions of your esophagus. How well the LES is working can
determine whether it is contributing to your acid reflux symptoms.
Gastric Emptying Studies
Gastric emptying studies determine how well food empties from your stomach.
About twenty per cent of patients with GERD have a slow emptying stomach.
In this test, you eat a meal containing a radioactive substance. A sensor
similar to a Geiger counter is placed over your stomach and measures how
quickly the radioactive substance in the meal empties from your stomach. If
you continue to have symptoms despite treatment, your doctor might
prescribe medication that speeds up stomach emptying. Alternatively, they
might do a surgical procedure to promote a more rapid emptying of your
stomach.
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Treating Acid Reflux and GERD With Medication andSurgery
There are several ways to manage GERD with medication. The best approach
to take depends on the frequency and severity of your symptoms, your
response to treatment, and any complications present.
For infrequent heartburn, life-style changes and an occasional antacid may be
all that’s needed. If heartburn is frequent, daily non-prescription strength H2
antagonists may be necessary. Also, a foam barrier can be used with the
antacid or H2 antagonist.
If these don’t work, you may need to consider prescription drugs. Your doctor
can assess you for possible complications based on the presence of
symptoms like a cough, asthma, hoarseness, sore throat, difficulty swallowing,
unexplained lung infections, or anemia. Your doctor will also look for diseases
with similar symptoms to GERD, such as gastric or duodenal ulcers.
If there are no symptoms or signs of complications and no likelihood of other
diseases, a trial of acid suppression using H2 antagonists often is a possibility.
If these aren’t effective, a second trial, with the more potent PPIs is often
offered. However, dependent upon severity, sometimes treatment begins with
a PPI and skips the H2 antagonist. If treatment offers complete relief, no
further evaluation is needed and the effective drug is often continued.
If there are symptoms or signs suggesting complicated GERD, or a different
condition is diagnosed, or if the medications don’t work, an endoscopy will
usually be carried out for further evaluation.
There are several possible results of endoscopy, each requiring different
treatment. If your esophagus is normal there are no traces of other diseases,
the focus is on relieving your symptoms. Therefore, prescription strength H2
antagonists or PPIs are given. If the esophagus is damaged, then the
treatment’s goal is to heal the damage. In this case, PPIs are preferred to H2
antagonists because they allow for better healing.
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If complications are found, treatment with PPIs also is appropriate. However,
the adequacy of treatment often needs to be evaluated with a ph study during
treatment with the PPI. Strictures may need to be treated by widening your
esophageal narrowing.
With Barrett's esophagus, endoscopic examinations are necessary to identify
pre-malignant changes. Also if symptoms don’t respond to the maximum
doses of PPI, there are two options.
The first is to perform ph testing to find out whether the PPI is ineffective or if
another condition is present. A higher dose of PPI may be tried. An alternative
is to add another drug that works in a different way, for example, a pro-motility
drug or a foam barrier. All three types of drugs can be used.
Medications
There are a number of antacids, which you can buy over the counter, or
medications that neutralize or inhibit acid production, or help muscles to
empty your stomach.
Antacids
Antacids are usually the first drugs recommended to relieve heartburn
symptoms and other GERD symptoms as they work to neutralize stomach
acid. The problem with antacids is that they empty from your stomach quickly
and acid can then re-accumulate.
The best time to take antacids is about an hour after your meals, or just before
your reflux symptoms begin. An antacid taken after a meal stays in your
stomach for longer. A second dose of antacids, about two hours after a meal,
replenishes the acid-neutralizing capacity within the stomach – although be
careful with the dosages as neutralizing acid can lead to reduced digestive
effectiveness.
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Many brands use different combinations of three basic salts -magnesium,
calcium, and aluminum - with hydroxide or bicarbonate ions to neutralize the
acid in your stomach.
There are some downsides to taking antacids.
Calcium-based antacids stimulate the release of gastrin, the hormone mainly
responsible for the stimulation of acid secretion. So, after the neutralizing
effect of the calcium carbonate is exhausted, the level of acid secretion in the
stomach increases (or rebounds) due to gastrin release, resulting in an
overproduction of acid.
The main benefits of Calcium antacids are that they are cheap and add
calcium to your diet. Taking these occasionally is ok, however long term use is
not recommended.
Magnesium based antacids can lead to diarrhea, and aluminum based ones
often cause constipation. Aluminum and magnesium salts can be combined in
a single product to balance their effects.
Common antacids include: aluminum hydroxide and magnesium hydroxide
(Maalox, Mylanta Maalox), aluminum hydroxide and magnesium carbonate
(Alka-Seltzer, Pepto-Bismol, Rolaids, and Riopan), calcium carbonate
antacids, (Tums, Titralac, and Alka-2), magnesium hydroxide (Milk of
Magnesium.)
Foaming Agents
Foaming agents work by covering your stomach contents with foam to prevent
reflux. They are best taken after meals and when you’re lying down, as this is
commonly when acid reflux strikes. Foam barriers aren’t often used as the first
or sole treatment for GERD, tend to be taken alongside other drugs to
improve overall symptoms. Foaming agents are helpful for people who do not
have damage to their esophagus. A common foam barrier, which is a
combination of aluminum hydroxide gel, magnesium trisilicate, and alginate is
Gaviscon.
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H2 Blockers
H2 blockers, or histamine antagonists, impede acid production. Histamine
attaches to receptors on your stomach's acid-producing cells and stimulates
cells to produce acid. H2 blockers work by blocking the receptor for histamine
and so preventing histamine from stimulating acid-producing cells. Therefore
reducing the amount of acid in the stomach, which reduces the risk of acid
reflux. They are referred to as H2 blockers because the specific receptor they
block is the histamine type two receptor.
H2 antagonists are best taken thirty minutes before meals. This is so the H2
antagonists will be at peak levels in your body after your meal when your
stomach actively produces acid. They can also be taken at bedtime to
suppress night-time acid production.
H2 antagonists are good at relieving symptoms of GERD but not very good for
healing inflammation that may accompany GERD. They are mainly used for
treating heartburn in GERD that is not associated with complications, and are
available in prescription strength and over the counter in non-prescription
strength.
H2 blockers provide short-term relief however, they are not designed to be
used for long term treatment. H2 blockers are effective for about half of those
with GERD symptoms. Four different antagonists are available by
prescription, including cimetidine (Tagamet), ranitidine (Zantac), nizatidine
(Axid), and famotidine, (Pepcid). All of these are also available over-the-
counter, without any need for a prescription. The dosages are lower in over-
the counter drugs than in those available by prescription.
Proton Pump Inhibitors
Proton pump inhibitors are available by prescription. PPIs work in a similar
way to H2 blockers, but are more effective and relieve symptoms in almost
everyone who suffers from GERD. PPIs block the secretion of acid into your
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stomach by the acid-secreting cells. PPIs are also good for protecting your
esophagus from acid so that inflammation can heal. They are used when H2
antagonists aern’t sufficient to relieve symptoms adequately or when there are
complications. They are best taken an hour before meals. Many people
benefit from taking H2 blockers at bedtime combined with a proton pump
inhibitor. Five different PPIs are approved for treating GERD, including
omeprazole (Prilosec), lansoprazole (Prevacid), rabeprazole (Aciphex),
pantoprazole (Protonix), and esomprazole (Nexium.)
Prokinetics
Prokinetics, or pro-motility drugs, help to strengthen your LES and encourage
your stomach to empty more quickly. They also improve muscle action in your
digestive tract. These drugs have side effects that limit their usefulness. Pro-
motility drugs are at their most effective when taken thirty minutes before
meals and again at bedtime. They are usually given to critically ill patients and
are not routinely prescribed for treating the symptoms or complications of
GERD.
As different drugs work in different ways, varying combinations of drugs may
help to control symptoms. People who get heartburn after meals may take
both antacids and H2 blockers. Antacids neutralize the acid in the stomach,
while H2 blockers act on acid production.
Surgery
Surgery is an option when drugs don’t work and lifestyle changes aren’t made.
GERD sufferers could consider surgery if regurgitation can’t be controlled with
drugs. This is particularly important if regurgitation results in infections in the
lungs, or occurs at night when aspiration into their lungs is more likely.
Surgery should also be considered if you need large doses of PPI or multiple
drugs to control your reflux. Some physicians recommend that all patients with
Barrett's esophagus should have surgery. This is based on a belief that
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surgery is more effective than drug treatment in preventing both reflux and
cancerous changes in your esophagus.
Surgery can help with the following:
� Esophageal stricture
� Barrett’s esophagus
� Life-threatening apnea
� Large hiatal hernia
� Failure of medical therapy to reduce severe symptoms
� Severe esophageal inflammation
� Recurrent pneumonia, chronic lung disease
� Failure to gain weight
Fundoplication
Fundoplication (usually Nissen fundoplication) is the standard surgical
treatment for GERD. Because of possible complications, it is usually done as
a last resort. Different types of fundos are performed: Nissen fundoplication
refers to wrapping the fundus, the top part of the stomach, all the way around
the LES.
A 180° wrap is called a Thal or Toupet fundo and a 90° wrap is known as an
anterior partial wrap. The upper part of your stomach is wrapped around your
LES to strengthen the sphincter thus preventing acid reflux.
Fundoplication surgery can be performed as open surgery or as a
laparoscopic procedure. Laparoscopic fundoplication means that the surgeon
uses a number of small incisions, and a special instrument that holds a tiny
camera is placed inside the body and its findings viewed with the aid of a
videoscope and TV monitors.
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Laparoscopic fundoplication has been used effectively in people of all ages,
even babies. Patients leave the hospital in one to three days and return to
work within a couple of weeks.
Not all fundoplications can be done in this way because of adhesions from
previous operations. In this case an open surgery fundoplication is needed.
The fundoplication works by keeping your lower esophageal sphincter closed
enough to prevent acid reflux while still allowing food to pass through your
esophagus and into your stomach.
Potential Complications of Fundoplication
Every surgery comes with risks. Fundoplication can have the additional
complications listed below.
� An inability to burp or vomit
� Gas bloat syndrome
� The heartburn returns
� Difficulty eating
� Dumping syndrome (the stomach empties too quickly and causes
nausea, abdominal cramping, retching, pale skin, hypoglycemia, and
sweating.)
� Disruption of the wrap (stitches come undone)
� Dysphasia (swallowing problems)
� Hiatus hernia
Surgery can be effective at relieving symptoms and treating GERD
complications for between 50 – 90% of cases. However, patients often
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continue having to take medication, although symptoms are usually improved.
The long term success of the surgery is not clear with one study showing that
16% of people had to have a second operation within10 –12 years to deal
with complications caused by the initial surgery.
Endoscopy
A number of endoscopic techniques for the treatment of GERD have been
developed. One type involves suturing the area of your lower esophageal
sphincter to tighten the sphincter, which stops acid escaping from the
stomach.
A second endoscopic procedure involves applying radio-frequency waves to
the bottom of your esophagus just above the sphincter. The waves damage
the tissue underneath the esophageal lining and a scar forms. The scar
shrinks and pulls on surrounding tissue, tightening the sphincter and the area
just above it.
A third type of endoscopic treatment involves injecting material into your
esophageal wall in the area of your LES to increase pressure in your LES and
prevent reflux. This is not actually surgery and has the advantage that
hospitalization isn’t necessary.
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Treating Acid Reflux, GERD and Heartburn Naturally
Lifestyle Changes
Eating Habits
The first step is to eat smaller, more frequent meals. Large meals expand your
stomach and increase upward pressure against your esophageal sphincter.
Avoid lying down for at least two hours after you eat. Staying upright allows
gravity to help keep your stomach acid from entering the esophagus and
helps the flow of food and digestive juices from your stomach to your
intestines.
Smoking
If you’re a smoker now is the time to give up. Apart from being generally bad
for your health, smoking relaxes your esophageal sphincter allowing acid to
escape more easily. Smoking also stimulates the production of stomach acid
and can hinder saliva production, a natural acid neutralizer. For help with
stopping smoking visit Stop Smoking Once And For All. Follow the 4-step
plan and say goodbye to cigarettes forever.
Weight Loss
Being overweight is one of the biggest risk factors for developing acid reflux
and GERD. It is though that being overweight increases abdominal pressure,
which can then push your stomach contents upwards, placing pressure on the
LES. According to some statistics, approximately thirty-five per cent of
overweight people experience heartburn. For many people, as little as a ten
per cent decrease in weight improves heartburn symptoms.
So, if you’re overweight losing the excess pounds can make big difference to
acid reflux and GERD symptoms.
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Alcohol
Alcohol is another common cause of acid reflux. It irritates and erodes the
mucous lining of your stomach and increases the amount of stomach acid
produced. Alcohol also has a general relaxant effect on muscles, including the
LES.
Relaxation
While stress hasn't been linked directly to heartburn, it is known that it can
lead to patterns of behavior that can trigger heartburn like overeating, eating
the wrong sort of foods, drinking alcohol excessively and smoking. Relaxation
techniques can alleviate stress making stress-related heartburn less likely.
Stress is any factor that causes tension.
Exercise
While the wrong sort of vigorous exercise can aggravate acid reflux, moderate
exercise can be helpful in fighting acid reflux as it aids digestion. Sometimes
chest pain following exertion is described as heartburn when in fact it can be
angina. Anyone with chest pain during or after exercise should be evaluated
for heart problems. In general however, regular exercise is known to help
lower stress and increase your endorphins (natural feel good chemicals.) Try
walking or cycling. Exercise that involves running, jumping or puts strain on
your LES like weightlifting can bring on acid reflux, so these forms of exercise
are best avoided.
Dressing Sensibly
What you wear can also have an impact on your acid reflux / GERD
symptoms. Avoid belts or clothes that fit tightly around your waist. Clothes that
fit tightly around your abdomen squeeze your stomach, forcing food up
against your LES, and can lead to reflux. Types of clothing that may cause
problems include tight-fitting belts and slenderizing undergarments.
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Sleep
For many sufferers reflux is worse at night. This is partly due to the loss of
gravity helping to keep food and acid in your stomach as it does when you’re
upright. This allows refluxed liquid to travel further up your esophagus and
remain in your esophagus for longer.
To counter symptoms at night elevate your head and chest while you sleep,
as lying flat presses your stomach's contents against your LES. With your
head higher than your stomach, gravity helps to reduce the pressure. You can
place bricks or blocks securely under the legs at the head of your bed. You
can also use an additional pillow, or a wedge-shaped pillow, to lift your head.
It is important that your upper body and not just your head is elevated.
Elevating your head alone does not raise your esophagus and so fails to
restore the effects of gravity. Reflux also occurs less frequently when you lie
on your left rather than on your right side as this helps with stomach emptying.
Summary of Quick & Easy Lifestyle Tips
� Stop smoking
� Avoid alcohol
� Lose weight if necessary
� Eat smaller meals more often
� Wear loose-fitting clothes
� Avoid lying down directly after a meal
� Raise the head of your bed by using blocks of wood or elevate your
head and chest with a wedge pillow
Dealing With Stress
Stress comes in many forms and affects all types of people. There is no way
of predicting stress levels in individuals. The degree of stress in your life
depends on a number of factors such as your health, your relationships, and
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your responsibilities. If you are poorly nourished, get inadequate sleep or have
inadequate social support networks, you are likely to experience higher stress
levels.
The symptoms of stress can be highly varied. It can induce headaches, cause
feelings of anger, anxiety, or tension. High levels of stress negatively affect
your immune system and other medical conditions. Stress can also encourage
behaviors that can worsen acid reflux and GERD.
There are many simple and inexpensive ways of reducing stress in your life.
Eating a well-balanced diet, avoiding caffeine and taking regular exercise
have all been proven to reduce stress levels. Going outdoors and enjoying the
sunshine can also be helpful.
Aromatherapy can help to reduce stress. Five to six drops of lavender oil in a
warm bath or a few drops on a cloth to inhale during the day has a strong
relaxing effect.
The first steps to relaxation involve making time for yourself. Once your own
needs are met, it’s easier to find more time for others. Deep breathing
exercises, massage, guided imagery and a healthy sex life help to reduce
feelings of stress.
A good way to dealing with stress is to learn how to relax. Choose somewhere
comfortable to lie down, remove your shoes and loosen any tight clothing.
Stretch out with your arms by your side, feet slightly apart and eyes closed.
Allow yourself to become calm and quiet. Close your eyes and feel your
body’s weight. Inhale slowly and allow your mind to go blank. As you exhale,
sink deeper into your support. Inhale through your nose, hold the breath, and
then exhale as if you were blowing air through a straw. Empty your lungs and
inhale deeply. You now need to go through your body, from top to bottom,
letting go of tension. Begin by thinking of your scalp. Think about releasing
tension and feel it relax. Then think of your forehead. Imagine those muscles
feeling relaxed and comfortable. Do the same with your eyes, mouth, and jaw.
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Feel your whole head relax and move onto your neck and throat. Continue
down your body, imagining each part of it letting go of tension and the
muscles in that area of your body relaxing. When you have reached your toes,
let the energies flow through your body. Remain in this relaxed state for five or
ten minutes. Blank your mind and enter a state of light sleep. When you’re
ready to awaken, tell yourself that you are deeply relaxed and ready to wake
feeling refreshed. Open your eyes and stretch your arms. Sit up and stretch
again.
To maximize results, practice this technique at least once a day for two
weeks. After this, regular relaxation sessions – for example, four times a week
– will maintain your relaxation response. Finding time for relaxation should be
a high priority.
Herbal Treatments
One important thing to remember about natural medicines as opposed to
prescription drugs is that it can often take longer before results are seen. Each
person's system is different, so it’s important to give the treatment an
opportunity to have the desired effect before deciding whether to discontinue
use. Also, you may find that one specific herbal treatment is not right for you,
however, trying a different herbal approach may bring results. It pays to keep
trying until you find the right combination or herbal treatment.
Herbal treatments need not replace your current medication, but can be used
to supplement it. When you first decide to use a new herbal treatment check
for interactions with any medication first. You should note any reaction you
have to it and if there are adverse effects, stop use immediately. Start with a
low dose and build up gradually. The efficiency of herbal medicine is partly
dependent on it being in your system continually so don’t expect results after
just one ‘dose’.
Herbs That Decrease Stomach Acid
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Meadowsweet, slippery elm, flax, liquorice, calendula, wild yam
Meadowsweet works by reducing acid production in the stomach as it has
antacid properties. It also helps to soothe and heal the esophagus.
Slippery elm is easy to digest and can be made into gruel. Slippery Elm has
traditionally been used to treat sore throats. It is believed that it helps reduce
acid reflux as the inner bark of the plant contains mucilage (a gel-like
substance) that swells when added to water. When swallowed this coats the
esophagus and can alleviate irritation caused by reflux.
Licorice extract – DGL – can be used to treat heartburn and stomach and
esophagus ulcers. Ordinary Licorice shouldn’t be used by patients with high
blood pressure or heart disease.
Herbs That Relieve Indigestion and Intestinal Irritation (carminative)
Chamomile, ginger, peppermint.
Chamomile is widely recognized for its calming properties and is thought to
help relieve irritation in the esophagus and aid proper digestion. It can help to
lower stomach acid due to its high calcium content. Drinking chamomile tea
after meals can relieve esophageal irritation. It also acts as an anti-
inflammatory. Chamomile oil is a potent uterine stimulant that should be
avoided during pregnancy, but the dried or fresh herb is safe in moderation.
Ginger assists proper digestion by promoting intestinal movement. Also,
ginger has anti-inflammatory and anti-nausea properties. It has been found to
help in dealing with morning sickness during pregnancy and is commonly
taken for motion sickness.
Peppermint is also believed to be useful against indigestion, and also calms
the gastrointestinal tract. One study of peppermint in combination with
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caraway fruit found it eased the symptoms of heartburn. A drop put on the
tongue or added to a glass of water can help with heartburn. As it’s a uterine
stimulant you should avoid the oil entirely if pregnant, although low doses of
the dried herb can be used.
Warning: peppermint may induce acid reflux and GERD symptoms in some
sufferers so use with caution.
Bitter Digestive Stimulant
Blessed thistle
Blessed thistle promotes digestive enzyme production and helps alleviate
heartburn. Traditionally, it’s used to ease gas, prevent constipation, and ease
general stomach pains. Its bitterness stimulates digestive activity and
improves digestion.
Soothing Agents
Aloe vera, slippery elm, marshmallow, papaya.
Aloe vera juice can be drunk to heal the intestinal tract, but it shouldn’t be
taken if you’re pregnant. Chewable papaya tablets can be purchased and they
are helpful reducing heartburn. Alternatively, you can drink papaya tea.
Marshmallow root helps reduce irritation of the esophagus and relieve
heartburn.
Others
Fennel
Fennel has been used for centuries to aid digestion. You can eat fennel seeds
or make a tea from them. If eaten, consume between five and seven grams
daily. To make a fennel tea boil 250 ml of water, add two to four grams of
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crushed seeds, and steep for ten to fifteen minutes. Keep the pot covered so
the oils in the fennel seeds don't evaporate. Allow to cool, strain, and drink
three cups a day. Or you can take two to four ml of fennel tincture three times
a day. Fennel is a uterine stimulant in high doses and should be used in
moderation during pregnancy.
Turmeric
Turmeric has a long history in Chinese and Ayurvedic medicine as being an
effective digestive. You can buy extract of turmeric as a tincture, or as tablets
or capsules. Half to one and a half ml of the tincture can be used up to three
times a day. In tablet or capsule form take four hundred to six hundred mg of
curcumin (the active ingredient of turmeric) three times a day.
Aniseed
Aniseed - or anise – is a powerful herb that helps to ease digestive conditions.
Use the ash-colored anise (green anise), European anise or sweet anise. The
other types of anise, star anise and caraway do not have the same beneficial
effects. Anise is a uterine stimulant in high doses, but safe as a culinary herb.
Use it in moderation during pregnancy, and avoid using the oil entirely.
Lavender
Lavender has enormous healing powers for your body. It is an excellent
stomach aid and is useful in reducing acid in the stomach. As lavender is a
uterine stimulant in high doses it should only be used in moderation during
pregnancy. It’s safe in cooking a culinary herb or for moderate use.
Almonds
Almonds can relieve heartburn. Eat almonds when heartburn symptoms
persist.
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Herbal Tea for Heartburn
One recipe that has helped sufferers is the following:
Mix equal amounts of aniseed, peppermint and lavender. Make an infusion.
Boiling two and a half cups of distilled water pour it water over a teaspoon of
the herbal mixture. Let the tea sit for three to five minutes. Strain the tea and
sweeten with honey if desired. You can drink up to eight ounces each morning
and evening.
Alternatively, try swapping your usual tea or coffee for a cup of chamomile
tea.
Digestive Enzymes
Digestive enzymes break down food particles so they can be utilized for
energy. Deficiencies in digestive enzymes can cause a number of abdominal
complaints. Enzymes are necessary to break down food particles into the
components your cells can use. You need them to build and repair bone and
tissue; to enable iron molecules to link with red blood cells so that they can
carry oxygen; detoxify your blood and tissues; and for your immune systems
to function.
Your body’s supply of enzymes is limited. For each ten years of life, you lose
about thirteen per cent of your enzyme potential. So consuming enzymes
through your diet is important to replenish supplies. Half of all adults don’t
produce enough digestive enzymes.
Digestive enzymes exist naturally in foods you eat raw. When foods are
cooked, the enzymes are destroyed and more stress is placed on your body
to produce digestive enzymes to help digest the food. Supplements can be
purchased that contain enzymes you can take in capsule form. Also,
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increasing your intake of raw foods will help. While all raw foods contain
enzymes, sprouting foods contain the highest concentrations of digestive
enzymes. Try adding sprouted seeds, grains, and legumes to your diet.
Betain, Pepsin, and Papaya Digestive Enzymes
As you age, your body’s ability to produce the hydrochloric acid needed to
digest protein lessens. Undigested protein can lead to the aggravation of or
cause acid reflux or heartburn. Digestive enzymes that contain Betain, pepsin,
or HCl taken with each meal can help you digest protein more efficiently.
Papaya enzymes (which contain papain), are also good for protein digestion
and you can take them at each meal. Use 500 mg or more of papaya
enzymes per meal.
Pineapples
Pineapples are a great natural source packed full of enzymes and contain
bromelain, an enzyme that helps digest protein. Pineapples support digestion,
reduce inflammation, and support wound healing. Fresh pineapple juice has
high levels of enzymes that can help prevent acid reflux. You can also buy
bromelain in tablet form and take from 200 to 500mg at each meal.
Diet
Sufferers with acid reflux can reduce symptoms by following a special acid
reflux diet. You need to know which foods are safe and those that trigger your
heartburn. Certain foods are known to be more likely to cause reflux than
others do. Changing your eating habits can be highly beneficial as reflux is
generally worse after meals. Eating earlier and having smaller evening meals
may help reduce the symptoms of reflux. A smaller meal results in less
stomach distension and by bedtime, a smaller meal eaten earlier meal is more
likely to have emptied from your stomach than a larger one eaten late.
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Foods that are common acid reflux triggers are:
• Chocolate
• Peppermint
• Alcohol
• Caffeinated and carbonated drinks
• Fatty foods
Other foods may also aggravate your symptoms, for example, spicy or acid-
containing foods, citrus juices, carbonated beverages, and tomato juice. Sulfur
containing vegetables (garlic, onions, leeks, broccoli, cauliflower, cabbage,
asparagus, and Brussels sprouts) can produce gas and this can exacerbate
reflux.
Chewing gum can be helpful in relieving symptoms for many acid reflux
suffers as chewing gum stimulates the production of bicarbonate-containing
saliva and increases your swallowing rate. After you swallow your saliva it
helps neutralizes any acid in your esophagus. However, this remedy does not
work for everyone and can even bring on symptoms in some people. But the
majority does seem to find it helpful.
Some foods have been shown to be acid reflux neutral for many. However,
people do vary, so you may find you can eat the foods from the "danger"
group with no problem or have problems with foods listed as safe. It’s a good
idea is to keep a food diary. For about two weeks, write down everything you
eat, when you eat, and details of any symptoms you experience. This will give
you an idea of what your personal safe foods are.
Often acid reflux sufferers can enjoy some ‘trigger’ foods occasionally and in
small amounts. They may trigger heartburn if they are consumed frequently or
in large amounts. You may find that you can eat these foods with no
problems, or you may have to avoid certain foods on this list entirely. Again, a
food diary will help here.
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The most effective diets are those that are made up of whole foods from both
plant and animal kingdoms. Staying away from processed and packaged
foods as much as possible can make a big difference to your symptoms.
Summary of Quick Diet Tips
� Avoid eating two to three hours before bed.
� Eat smaller meals more often.
� Avoid alcohol.
� Avoid carbonated drinks, chocolate, caffeine, and foods that are high in
fat or contain a lot of acid, or spices.
� Limit acid containing foods.
� Avoid hard candy, which increases the amount of swallowed air.
� Don’t drink from a straw.
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Food Table
The table below lists the different foods that can signal danger, are usually
OK, or can be eaten in moderation. Your own personal experience may be
different, so you may eventually want to create your own list.
Danger Usually OK In Moderation
Alcohol
Barley (OK if purledbarley is cooked 10minutes)
Beans (gas producing)
Black Pepper (WhiteOK)
Broccoli
Brussels Sprouts
Buffalo wings
Cabbage
Caffeine
Carbonated Beverages
Cauliflower
Chicken nuggets
Chili Powder
Chocolate
Citrus fruits
Coffee (evendecaffeinated)
Corn
Cottage cheese, regular
Cranberry juice
Apple
Baked potato
Banana
Bread, multi grain orwhite
Cabbage
Carrots
Cereal, bran or oatmeal
Cheese, feta or goat
Chicken breast, skinless
Cookie, fat free
Corn bread
Cream cheese, fat free
Egg white
Fish
Graham crackers
Green beans
Ground beef, lean
Jelly beans
Mineral water
Peas
Potato chips, baked
Apple cider
Beer
Blueberries
Cheddar cheese
Chicken salad
Cola
Cookie, low-fat
Cottage cheese, low-fat
Cranberries, dried
Eggs, fried
Fish, fried
Frozen yogurt
Garlic bread
Granola cereal
Grapes
Ground beef, lean
Ham
Hot dog, beef or pork
Ketchup
Leeks
Mozarella cheese
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Creamy Foods/Gravies(High fat content)
Cucumber
Foods with "air" such asfluffy baked goods
French fries
Fatty and fried foods
Garlic
Grapefruit juice
Gooey Pastries (High fatcontent)
Green Peppers
Ground beef, chuck
Guargum (thickener)
High Energy Foods(digest slowly)
Honey
Ice cream
Kale
Lemonade
Macaroni and cheese
Marbled sirloin
MCT Oil (medium chaintriglycerides, digestslowly)
Mashed potatoes
Meat extracts
Meat with connectivetissue/gristle (takelonger to digest)
Milk (lactose intolerancecan provoke reflux insome people)
Pretzels
Red liquorice
Rice
Rice cakes
Salad dressing, low fat
Sour cream, fat free
Soy cheese, low fat
Steak
Muffin
Non-alcoholic beer
Onion, cooked
Orange juice, low-acid
Peach
Raspberries
Root beer
Sauerkraut
Scallions
Scrambled eggs, inbutter
Strawberries
Tuna salad
Yogurt
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Milk shakes
Molasses
Oats (rolled oats OK)
Onion
Pectin
Peppermint/Spearmint
Sour cream
Spaghetti with sauce
Turnips
Rhubarb
Rye Seeds
Simple Sugar Foods
Spicy foods
Tea
Tofu (avoid largequantities)
Tomato
Vinegar
Recipes
These recipes are ideal for anyone on an acid reflux diet. There are
suggestions for breakfast, lunch, dinner, dessert and snacks. You can amend
the recipes by substituting other foods if one of the ingredients is something
you are sensitive to. Although you may not normally take breakfast, eating a
number of small meals a day rather than having three larger meals has helped
many people relieve their symptoms.
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Breakfast Suggestions
One English muffin with one tablespoon of margarine.
Eight ounces of skim milk.
Half a cup of sliced peaches.
One cup of hot oatmeal cereal with eight ounces of skim milk
Half a cup of papaya slices.
Two slices of whole wheat bread
One tablespoon of margarine
Half a cup of puffed wheat cereal with eight ounces of skim milk.
Two slices of whole-wheat toast with one tablespoon of margarine.
One small banana
One cup of bran flake cereal with eight ounces of skim.
One English muffin with one tablespoon of margarine.
One cup of fresh or frozen strawberries.
One cup of hot oatmeal cereal with eight ounces of skim milk.
Two slices of whole-wheat toast with one tablespoon of margarine.
One cup of unsweetened apple sauce.
Eight ounces of skim milk
One bagel with one tablespoon of peanut butter or low-fat cream cheese.
One small banana
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Lunch Options
Stuffed Tuna Pocket
One whole grain pita bread
Four ounces of water-packed tuna
Two tablespoons of low fat mayonnaise
One-quarter cup of cucumber slices
Lettuce leaf
Soup and Sandwich
One and a half cups of cream of chicken soup
Two slices of whole-grain bread
Four ounces of deli-style sliced chicken
One tablespoon of low-fat mayonnaise
Lettuce leaf
Half a cup of raw carrot sticks
Turkey Sandwich and Chips
Two slices of whole-wheat bread
Four ounces of oven-roasted turkey luncheon meat
One ounce of low-fat mayonnaise
Two ounces of baked potato chips
One cup of cottage cheese
One cup of sliced peaches
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Soup and Sandwich
One and a half cups of chicken noodle soup
Two slices of whole grain bread
One tablespoon of low-fat mayonnaise
Four ounces of deli-style sliced chicken
One cup of unsweetened applesauce
Half a cup of celery sticks
Chicken Wrap
One fat-free flour tortilla
Four ounces of diced chicken breast
Two tablespoons of low-fat mayonnaise
Half a cup of shredded lettuce
One ounce of low-fat shredded mozarella cheese
One cup of sliced peaches
Soup and Sandwich
Two cups of cream of potato soup
Two slices of slices whole wheat bread
Four ounces of white turkey luncheon meat
One tablespoon of low-fat mayonnaise
Two lettuce leaves
Half a cup of raw carrot sticks
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Main Course Ideas
Baked Pork Chops with Oregano
Eight large pork chops or steaks, with bones
One teaspoon of salt
Half a cup of apple cider or juice
Two teaspoons of dried oregano
Three bay leaves
One cup of chicken broth
Fresh chopped parsley to garnish
Method
Place the pork chops into a dish and sprinkle with salt. Drizzle apple cider
over them. Sprinkle on oregano. Place bay leaves between two of the chops.
Cover the dish with plastic wrap and refrigerate for at least four hours. Preheat
oven to 325 degrees. Heat a nonstick skillet on a high heat. Remove the pork
chops from the marinade, brown lightly on both sides. Place in a dish with the
marinade. Pour in chicken broth, cover dish with foil, and bake for two hours
or until the meat is tender. Garnish with parsley and serve. Serves six.
Beef Loaf
One and a half pounds of very lean ground beef
Two eggs
One and a half cups of breadcrumbs
Two tablespoons chopped parsley
Half a teaspoon of pepper
Two teaspoons of salt
Method
Preheat the oven to 350 degrees. Combine ground beef, unbeaten eggs,
breadcrumbs, chopped parsley, pepper and salt. Blend the mixture
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thoroughly. Place in a bread pan. Bake for about two hours. Baste every
quarter of an hour with hot stock. Cut into thin slices. Serves four.
Broiled Lamb Chops with Mushrooms
One and a half tablespoons of vegetable oil
One quarter teaspoon of salt
Two teaspoons of ground ginger
Three cups of sliced mushrooms
Four 4 oz lamb chops, each one inch thick with visible fat trimmed
One and a half cups of long-grain brown rice, cooked without salt or fat
Method
Combine the vegetable oil, salt, and ginger. Place rack in a pan, and lamb
chops on the rack. Brush the top of the lamb chops with the oil mixture. Broil
for five minutes. Turn the lamb chops and place mushrooms around them.
Brush lamb chops with the remaining oil mixture. Broil for five more minutes.
Serve immediately with cooked rice. Serves four
No Tomato Sauce Lasagna
Twelve ounces of very lean ground beef
Half a cup of beef broth
Twelve ounces of wide lasagna noodles
Two cups of low-fat alfredo sauce
One and a half cups of grated mozzarella cheese
Method
Preheat the oven to 375 degrees. Cook the noodles in boiling water until just
tender and drain. While noodles are cooking, brown the ground beef. Add
browned beef and broth to noodles. Toss together. Spread one cup of the
alfredo sauce on the bottom of a pan. Add three strips of lasagna.
Spread half of the beef mixture on top. Lay three strips of lasagna noodles.
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Spread the remaining beef mixture on top. Add another three strips of lasagna
noodles. Spread the top with remaining white sauce and sprinkle with grated
mozzarella cheese. Bake for twenty-five to thirty-five minutes. Serves eight.
Pasta and Ham
Twelve ounces of uncooked pasta
Two tablespoons of olive oil
One 14.5 ounce can of reduced-sodium chicken broth
Three quarters of a teaspoon of dried basil, crumbled (or one tablespoon
fresh)
Four ounces of low-sodium boiled ham, thinly sliced and cut into half inch
strips
Grated Parmesan cheese
Method
Cook the pasta. Heat the oil in a medium saucepan over a medium heat. Pour
in the broth and stir in the basil. Cook for three minutes, or until it just starts to
boil. Drain pasta. Return the pasta to the pan and pour in the broth. Add the
ham to the pasta and toss well to combine. Cook for about two minutes over
medium-high heat, or until piping hot. Serves four.
Tuna Noodle Casserole
Eight ounces of elbow macaroni, uncooked
One six ounce can of water-packed tuna, drained
One cup of sliced celery
One can (10¾ oz) reduced-fat cream of celery soup, undiluted
Half a cup of skim milk
One cup of shredded, reduced-fat sharp cheddar cheese
Half a cup of low-fat mayonnaise
Method
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Cook macaroni and drain. Rinse with cold water. Drain again. Combine the
cooked macaroni, tuna, and celery. Mix well, and set aside. Combine soup
and milk In a small saucepan and heat over a medium heat until smooth. Add
the cheese and continue to heat until the cheese is melted. Remove the soup
from the heat. Add mayonnaise to soup and stir until well blended. Pour the
soup over the macaroni mixture. Mix well. Pour macaroni and soup mixture
into casserole dish. Bake at 350 degrees, uncovered, for thirty minutes.
Vegetable Beef Stew
One tablespoon of vegetable oil
One pound of beef stew meat
One can (14 oz) of beef broth
Two thirds of a cup of water
Three and a half cups of red potatoes, cubed
Two cups of sliced raw carrots
Half a cup of sliced celery
Half a cup of frozen peas
Method
Add vegetable oil and heat until oil is hot. Next, add the stew meat and cook
for three to four minutes, (until browned on all sides) Remove the beef and set
aside. Add beef broth and water to saucepan. Add the potato cubes, carrots,
and celery. Heat until boiling and then add the beef to the vegetables and
broth. Cover, reduce heat, and simmer for half an hour, or until the meat is
tender. Add frozen peas. Cook for an additional two minutes. Serves four.
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Tempting Desserts
Angel cake
One cup of superfine sugar, divided into one three quarter cup and one
quarter cup portions
One cup sifted cake flour
Twelve large egg whites, at room temperature
One teaspoon cream of tartar
Half a teaspoon of salt
Two teaspoons of vanilla extract
Method
Preheat the oven to 375 degrees. Whisk together the three quarter cup of
sugar and the flour. Beat the egg whites until they’re thick and foamy. Add
cream of tartar, salt, and vanilla. Beat until soft peaks form. Sprinkle the
remaining sugar gradually over the top of the batter and continue to beat until
stiff and glossy. Fold the flour mixture into the egg white mixture, using a
rubber spatula or slotted spoon. Pour into an ungreased ten inch tube pan
with removable sides. Use a knife to cut through the batter to eliminate air
pockets. Bake for thirty to thirty five minutes. Invert the cake over a funnel, or
a narrow bottle to cool.
Apple Cinnamon Coffee Cake
Filling and topping
Two tablespoons of cinnamon
Five tablespoons of sugar
Six cups of chopped apples
Cake
Two cups of sugar
One cup of applesauce
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Four teaspoons of vanilla
A pinch of salt
Four lightly beaten eggs
Three cups of flour
One tablespoon of baking powder
One teaspoon of nutmeg
Method
Preheat the oven to 350 degrees. Spray a nine inch baking dish with nonstick
cooking spray.
Filling and Topping
Combine the cinnamon and sugar in a bowl. Set aside one tablespoon of the
mixture. Add apples to the remainder of the mixture and toss until apples are
coated.
Cake
Whisk together the sugar, applesauce, vanilla, salt, and eggs. Combine flour,
baking powder, and nutmeg and fold into sugar mixture. Spoon one third of
the batter into the pan. Cover with half of apple mixture, then spoon in
remaining batter. Place apple slices on top. Sprinkle top lightly with the set
aside cinnamon and sugar. Bake for one hour.
Banana Cupcakes with Cream Cheese Frosting
Cup cakes
One cup of flour
Half a teaspoon of baking soda
One quarter of a teaspoon of salt
Half a teaspoon of ground cinnamon
Three quarters of a cup of granulated sugar
One quarter of a cup of butter
One teaspoon of vanilla extract
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Half a cup of mashed ripe bananas
Four large egg whites
One quarter of a cup of fat-free sour cream
Frosting
One and a half cups of powdered sugar
Eight ounces of softened fat-free cream cheese
One teaspoon of vanilla extract
Method
Preheat oven to 350 degrees. Stir together flour, baking soda, salt, and
cinnamon until well blended. Set aside. Cream together sugar and butter. Add
the vanilla and mashed bananas to the creamed sugar and butter and beat
well. Add egg whites to the mixture and beat thoroughly. Stir in half the flour
mixture and the sour cream. Add the remaining flour mixture, and stir until
combined. Spoon into greased twelve muffin cups. Bake for twenty-five to
forty minutes, or until a toothpick inserted into the center comes out clean.
Cool for fifteen minutes before removing the cupcakes from the pan, and cool
cupcakes completely before frosting them. To make the frosting, beat all the
frosting ingredients together until creamy. Spread the frosting thinly over the
cupcakes using a knife or spatula.
Berry Cobbler
Two cups of all-purpose flour
One cup of white sugar
Two and a half teaspoons of baking powder
Half a teaspoon of salt
Three tablespoons of melted butter
Two thirds of a cup of milk
One teaspoon of vanilla extract
One beaten egg
Two cups of raspberries (other berries can be substituted)
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Method
Preheat oven to 350 degrees. Blend together flour, sugar, baking, powder and
salt. Stir in butter, milk, vanilla and egg until the mixture is smooth. Fold in
berries.
Pour into prepared pan, and bake for thirty-five to forty minutes, or until top is
firm.
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Treating Reflux in Pregnancy and Infancy
Pregnancy
It may not be possible to eliminate heartburn completely during your
pregnancy, but you can take steps to minimize your discomfort. In addition to
avoiding the known triggers listed above:
� Don't eat big meals. Eat several small sized meals throughout the day
instead.
� Don't rush your meals as this can make digesting the food harder and
you are likely to swallow lots of air.
� Wait at least three hours after your last meal before going to bed.
It is important to drink water during pregnancy, along with other fluids, but
don't drink only at mealtimes. Large quantities of fluids can distend your
stomach, and put more pressure on your LES forcing it to open. Drink fluids
regularly throughout the day.
Sleep with your head and shoulders propped up with a pillow, or elevate the
head of your bed a few inches. This will allow gravity to work in your favor,
and help keep your stomach acids where they should be. A wedge pillow can
make this more comfortable.
Wear loose and comfortable clothing. Avoid tightness around your waist and
stomach. Remember to bend at your knees instead of at your waist. Bending
at your waist puts pressure on your stomach and can cause reflux. Sit upright
in a comfortable chair rather than slouching.
Try not to put on too much weight. Gaining too much additional weight puts
more pressure on your stomach, and can force your stomach contents
through your LES and into your esophagus.
If lifestyle changes aren’t enough treatments that are only minimally absorbed
into the body, and not a potential threat to the fetus, can be used. You should
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check with your doctor before taking any remedies while pregnant, but there
are generally some you can take that will help to eliminate heartburn. Tums,
Maalox, Titralac, Mylanta, Riopan, or Gaviscon may prove helpful.
It’s best to start with antacids, an hour after meals and at bedtime. You may
need to alternate magnesium and aluminum-containing antacids to avoid
diarrhea or constipation. If antacids alone aren’t effective, then alginic
acid/antacid may be added. The antacids and alginic acid/antacid should be
taken after meals and at bedtime and more frequently if necessary.
If sucralfate is being used, it should be taken half an hour before or after
antacids or alginic acid/antacid. Sucralfate acts by coating and protecting the
lining of your esophagus and stomach and is more effective in an acidic
environment.
Some antacids contain aluminum, and small amounts of aluminum are
absorbed into your body. However, it doesn’t accumulate in your body unless
you have kidney impairment. Therefore, absorption of aluminum is unlikely to
cause a problem for the fetus unless you have kidney impairment.
In theory, magnesium containing antacids could slow your labor. This problem
would only apply if they were taken just prior to labor.
Antacids can inhibit iron absorption, and iron is important for the growing
baby. Pregnant women usually receive iron supplements and a slight
decrease in iron absorption should not result in a deficiency of iron, but check
with your doctor.
After antacids, the safest absorbed drugs that can be given are H2
antagonists. Animal studies haven’t shown any effects on the fetuses of
pregnant animals. Nitzadine shouldn’t be used because effects on animal
fetuses have been shown.
Proton pump inhibitors should be used only when H2 antagonists fail to control
heartburn. Omeprazole should be avoided as it has been shown to have
effects on the fetuses of animals at high doses.
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Concern about the use of H2 antagonists and proton pump inhibitors are
greatest in the first three months of pregnancy, when there is more danger of
abnormality being caused in the fetus. It is less of a problem later in
pregnancy as the fetus has done most of the development by this stage.
It is important to consult your doctor before taking any medication for acid
reflux and heartburn.
Infancy
Many babies have problems with spitting up that don't require treatment. Their
symptoms usually disappear after six or eight months. For some infants their
symptoms are a sign of something more serious that may need medical
attention. A doctor should be consulted if you have any concerns. It’s also
important to take advice before making significant changes in feeding.
Reflux treatment depends on the infant’s symptoms and age. If your child is
uncomfortable, finds it hard to sleep or eat, or fails to thrive, your doctor may
suggest medications. If your child continues to have symptoms, tests may be
arranged to help find better treatments. Occasionally, if the problems are
severe, surgery may be the best option. It’s rare for children to need surgery
for GERD. Most infants don't need medication and outgrow reflux by one or
two years of age.
Thickened feeding can reduce the amount your baby will regurgitate. Cereal
adds weight to the food, which helps to keep the food from splashing around
in the baby's stomach and can help keep it down. Babies who are having
problems in gaining weight may also benefit from the added calories. Add up
to a tablespoon of rice cereal to two ounces of formula. If the mixture is too
thick, you can change the teat nipple size, or cross cut the nipple. Some
babies have reactions to rice that make their reflux worse. In these cases,
adding oatmeal instead may prove to work.
Burping your baby frequently during feeding can help minimize gastric
pressure and reflux. Waiting to burp your baby after they have a full stomach
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can increase the chances of regurgitation. Burp your baby after one or two
ounces of formula are taken. Burp breastfed infants after feeding on each
side. Sucking on a pacifier increases saliva production, which can help to
neutralize some of the acid that may come up.
Feeding every two to three hours when your baby is awake will reduce reflux.
Overfeeding can increase abdominal pressure and lead to gastric reflux.
Avoid tight elastic around the waist, and keep diapers as loose as possible.
Keep your child upright during feeding and hold your infant upright in your
arms for half an hour after feeding. Formula fed babies may require longer
periods for feeding, since formula is digested more slowly than breast milk.
If you lay your baby down after feeding, place them on their stomach on an
incline of at least thirty degrees. This can reduce regurgitation. But only place
your baby in this position if they are awake. Lying a baby on the stomach is
not recommended during sleep, because of the link between this position and
sudden infant death syndrome. Putting a baby to sleep on their stomach is
only considered where the risks from GER complications outweigh the
potential increased risk of SIDS, but this should be discussed with a doctor
first.
Elevate the head of the crib by thirty degrees to allow gravity to help keep
stomach contents where they belong.
The way an infant is positioned in a car seat can cause an increase in
regurgitation. Slouching over causes abdominal compression, increasing the
risk of reflux. Using simple supports to keep them upright will prevent this. Use
a car seat that allows your baby to be reclined enough that they aren't
slouched.
If you breastfeed it can be helpful to avoid foods associated with reflux (see
the previous section on trigger foods). Breastfeeding is best for a reflux baby
because it is more hypoallergenic than formula and is more easily digested.
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If eliminating foods from your diet seems to help, you can slowly introduce one
thing at a time back into your diet and watch your baby's reactions. This way
you will know exactly what was making the reflux worse. Some children have
milk or gluten allergies or sensitivities to milk or gluten products, which can be
mistaken for reflux or worsen existing reflux. It’s a good idea to experiment
with different formulas, or eliminate milk and gluten products from your diet if
breastfeeding.
Try carrying your baby around as much as possible in a baby carrier
throughout the day. Carried babies tend to cry less and crying can make reflux
worse, plus, it keeps baby upright.
Also, infant massage may help to improve digestion and also can help to relax
your baby.
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Common Myths About Reflux and GERD
Excess Acid is the Only Cause of Heartburn
The amount of acid in the stomach of a GERD sufferer is usually normal. The
problem is often not the amount of acid but where it ends up – the esophagus.
It’s true that medication is given to reduce stomach acid. This is because
drugs do not effectively treat the underlying factors.
Acid Reflux Only Causes Problems in My Esophagus
Other conditions may be caused or worsened by acid reflux, including asthma.
GERD sufferers may also experience hoarseness caused by acid irritation in
the throat or around the vocal cords, or a chronic cough and sore throat. Acid
can also aspirate into the lungs leading to damage and infections and in
severe cases GERD can lead to Barrett’s esophagus, which can increase the
risk of esophageal cancer.
Stress Causes Heartburn
Stress does not cause heartburn, however stress can worsen symptoms as it
encourages behavior that often triggers acid reflux.
Nothing Can be Done About Heartburn and Acid Reflux
A full range of treatment is available, including prescription medication, non
prescription remedies, lifestyle and diet changes.
It’s My Fault I Have Heartburn
Although certain lifestyle habits and your food and drink choices may
aggravate your symptoms, some people make significant lifestyle changes
and can still experience heartburn. It’s a medical condition with real biological
causes and it can take trial and error to find an effective treatment /
management approach.
It’s Just a Fact of Life I Can't Control
You don’t need to suffer in silence. Diet and lifestyle changes, as well as
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medication, can provide relief for most sufferers. Surgery or non-surgical
techniques may be appropriate treatment options for some people.
Heartburn is Minor and Trivial
It’s common, but not trivial. Frequent heartburn can severely impact your
productivity, daily activities and quality of life. Persistent heartburn may be a
symptom of GERD, which if untreated, can cause or contribute towards a wide
range of problems including the development of Barrett’s esophagus, which
can be a precursor for esophageal cancer.
After Dinner Mints Offer a Soothing way to Drift off to Sleep
After dinner mints combine three common heartburn triggers—chocolate, mint
and lying down — making them likely to cause heartburn and are therefore
best avoided.
Antacids aren't Real Medicine
Because antacids are sold without a prescription some people believe they’re
not real medicine. They are medicine, and you need to be sure to follow
directions for taking them carefully as with any drug. If used in moderation and
occasionally, antacids are safe.
I Have to Live With my Heartburn
Lifestyle changes, dietary modifications and medication can effectively treat
and prevent heartburn as well as provide complete symptom relief
Smoking a Cigarette Helps Relieve Symptoms
Cigarette smoking makes acid reflux worse. Acid reflux occurs when the LES
relaxes, allowing the acidic contents of the stomach to back into the
esophagus. Smoking acts as a muscle relaxant allowing the LES to relax.
Give up smoking today.
You Need Surgery to Correct Chronic Heartburn
Many people who have surgery still take acid reflux medication regularly.
However, surgery maybe worth considering if medication fails to help.
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Nighttime Heartburn Sufferers Must Sleep Sitting Up
Rolling onto your left side can be just as effective. Sleeping on your right side
can aggravate acid reflux. Sleeping on your back allows acid to slip back into
your esophagus more often, but the acid takes longer to clear out when you
sleep on your right side.
All Chronic Heartburn Symptoms are Alike
Not all GERD sufferers experience typical heartburn chest pains. The
absence of heartburn does not mean you don’t have acid reflux / GERD.
Drinking Milk Before Sleep Eases Symptoms
Drinking milk can be a quick solution to a reflux problem. Unfortunately, milk
has a rebound action and eventually encourages secretion of more stomach
acid, which causes reflux.
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GERD at a Glance
GERD is a condition in which the acidic liquid contents of the stomach back
up into the esophagus.
The causes of GERD include an abnormal lower esophageal sphincter, hiatal
hernia, abnormal esophageal contractions, and slow emptying of the stomach.
GERD may damage the lining of the esophagus and cause inflammation.
The most common symptoms of GERD are heartburn, regurgitation, and
nausea.
Complications of GERD include ulcers and strictures of the esophagus,
Barrett's esophagus, cough and asthma, throat and laryngeal inflammation,
inflammation and infection of the lungs, and collection of fluid in the sinuses
and middle ear.
Barrett's esophagus is a pre-cancerous condition that requires surveillance for
the development of cancer.
GERD may be diagnosed or evaluated by a trial of treatment, endoscopy,
biopsy, x-ray, examination of the throat and larynx, esophageal acid testing,
esophageal motility testing, emptying studies of the stomach, and esophageal
acid perfusion.
GERD is treated with life-style changes, antacids, histamine antagonists (H2
blockers), proton pump inhibitors, pro-motility drugs, foam barriers, surgery,
and endoscopy.
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Medical disclaimer
This book contains information on a medical topic; however, no warranty
whatsoever is made that the medical information is accurate. There is
absolutely no assurance by the author that any statement contained in a topic
touching on medical matters is true, correct or precise. This book may have
been written, in part or in whole, by non-medical personnel. Even if a
statement made about medicine is accurate, it may not apply to you or your
symptoms. The medical information provided is, at best, of a general nature
and cannot substitute for the advice of a medical professional (for instance, a
qualified doctor/physician, nurse, pharmacist/chemist, and so on).
None of the individual contributors, system operators, developers, sponsors of
this book nor anyone else connected to this book can take any responsibility
for the results or consequences of any attempt to use or adopt any of the
information presented in this book or on the affiliated web site. Nothing in this
book should be construed as an attempt to offer or render a medical opinion
or otherwise engage in the practice of medicine.
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For More Information
American College of Gastroenterology (ACG)
4900-B South 31st Street, Arlington, VA 22206–1656
Phone: 703–820–7400
Fax: 703–931–4520
Internet: www.acg.gi.org
American Gastroenterological Association (AGA)
National Office, 4930 Del Ray Avenue, Bethesda, MD 20814
Phone: 301–654–2055
Fax: 301–652–3890
Email: [email protected]
Internet: www.gastro.org
International Foundation for Functional Gastrointestinal Disorders
(IFFGD) Inc.
PO Box 170864, Milwaukee, WI 53217–8076
Phone: 1–888–964–2001 or 414–964–1799
Fax: 414–964–7176
Email: [email protected]
Internet: www.aboutgerd.org
North American Society for Pediatric Gastroenterology, Hepatology and
Nutrition (NASPGHAN)
PO Box 6, Flourtown, PA 19031
Phone: 215–233–0808
Fax: 215–233–3939
Email: [email protected]
Internet: www.naspghan.org
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Pediatric/Adolescent Gastroesophageal Reflux Association Incorporated
(PAGER)
P.O. Box 1153
Germantown, MD 20875–1153
Phone: 301–601–9541
Email: [email protected]
Internet: www.reflux.org
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Glossary
Acid perfusion test – a test used to determine if chest pain is caused by acid
reflux
Adenocarcinoma – a type of esophageal cancer
Anemia - a drop in hemoglobin count
Antacid – neutralizes acid
Apnea - a period of more than ten to twenty seconds of interrupted breathing
Barrett's esophagus - Long-standing or severe GERD causes changes in the
cells that line the esophagus. These cells then become pre-cancerous, and
finally cancerous.
Body mass index - a measure of a weight in relation to height
Diaphragm - the muscle wall that separates the stomach from the chest.
Digestive enzymes - complex proteins involved in digestion that stimulate
changes in certain substances.
Duodenum - the first part of the small intestine that attaches to the stomach.
Endoscopy - suturing the area of the lower esophageal sphincter, which
tightens the sphincter; applying radio-frequency waves to the lower part of the
esophagus just above the sphincteror injecting material into the esophageal
wall in the area of the LES to increase pressure in the LES and prevent reflux.
Esophageal acid testing – a test where a sensor is placed in the esophagus to
detect the level of acidity there
Esophageal motility testing – a test to determine how well the muscles of the
esophagus are working.
Esophageal pH probe – a probe used to detect and record the amount of
stomach acid coming back up into the esophagus
Esophagus - carries food from the mouth to the stomach. Also called the
gullet.
Failure to thrive - when babies will not gain weight at an acceptable or safe
rate
Foaming agent - works by covering your stomach contents with foam to
prevent reflux
Fundoplication - wrapping the fundus around the esophagus
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Gastroenterologist – a doctor who specializes in internal medicine.
GERD - stands for gastroesophageal reflux disease. It’s an alternative name
for what many people call acid reflux and occurs when the lower esophageal
sphincter doesn’t close properly and stomach contents leak back, or reflux,
into the esophagus.
H2 Blockers/histamine antagonists - histamine attaches to receptors on the
stomach's acid-producing cells and stimulates the cells to produce acid. H2
blockers work by blocking the receptor for histamine and so prevent histamine
from stimulating the acid-producing cells.
Heartburn – also called acid indigestion. A burning chest pain beginning
behind the breastbone and moving upwards to the neck and throat.
Hiatal hernia - when the upper part of the stomach is above the diaphragm
Lower esophageal sphincter (LES) - a ring of muscle at the bottom of the
esophagus that acts like a valve between the esophagus and stomach.
Pepsin - an enzyme that begins the digestion of proteins in the stomach that
are produced by the stomach.
Prokinetics/pro-motility drugs - help to strengthen the sphincter and makes the
stomach empty faster
Proton pump inhibitors - blocks the secretion of acid into the stomach by the
acid-secreting cells
Refluxed liquid – liquid returned from the stomach.
Regurgitation - when refluxed liquid returns to the mouth
Ulcer - a break in the lining of the esophagus that occurs in an area of
inflammation.