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accreditation The Yale School of Medicine is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

designation statement The Yale School of Medicine designates this live activity for a maximum of 5.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

financial support The Yale School of Medicine, Department of Obstetrics Gynecology & Reproductive Sciences is grateful to its supporters. They are acknowledged in all conference materials.

disclosure policy It is the policy of Yale School of Medicine, Continuing Medical Education, to ensure balance, independence, objectivity and scientific rigor in all its educational programs. All faculty participating as speakers in these programs are required to disclose any relevant financial relationship(s) they (or spouse or partner) have with a commercial interest that benefits the individual in any financial amount that has occurred within the past 12 months; and the opportunity to affect the content of CME about the products or services of the commercial interests. The Center for Continuing Medical Education will ensure that any conflicts of interest are resolved before the educational activity occurs.

directions Yale West Campus Conference Center, 100 West Campus Drive, Building 800, Orange, CT.

Coming from the South. If you are coming from the South (New York), take I-95 North and get off at Exit 41 (Marsh Hill Rd). At the end of the ramp, go straight through the light. This is Frontage Road and the entrance ramp to I-95 Northbound. Stay in the right lane and bear right at the fork. Follow signs to Conference Center.

Coming from the North. If you are coming from the North (Hartford/New Haven/Madison, etc.), take I-95 South. Get off at Exit 41 (Marsh Hill Rd). At the light at the end of the exit ramp take a left onto Marsh Hill Road. At the next traffic light, take a left onto the Frontage Road/I-95 Northbound entrance ramp. Follow this to the fork, stay in the right lane. Follow signs to Conference Center.

Coming from the Merritt Parkway. Take the Merritt Parkway North to Exit 54 (Milford Connector). Go under the I-95 overpass and exit onto the ramp designated to New Haven (I-95 North). Get off at Exit 41 and continue with the directions above (Coming from the South) to reach West Campus.

GPS Users: If your GPS is not up-to-date, enter 141 Frontage Road, Orange, CT to arrive at destination.

parking informationComplimentary parking is available on-site.

Registration Information

34th Annual Ella T. Grasso Memorial Conference Wednesday, November 28, 2018

registration fees

Registration fee* includes all conference materials, continental breakfast, refreshment breaks, and lunch:

Physicians – $100 Nurses/PAs/Allied Health Professionals – $50Non-Yale/UConn Residents/Fellows/Students† – $25 Yale and UConn Residents/Fellows/Students† – complimentary, registration required

*All cancellations must be received in writing (or via e-mail) at least one week prior to the start of the conference to receive a refund. Any requests for refunds received after this date, or by telephone, will not be honored.†A letter of verification from department head must accompany registration. Letter should be sent separately to Yale CME at the above address. You may also e-mail a pdf copy of your verification letter to cme@yale.edu.

If you have any questions, please contact Yale CME at cme@yale.edu or 203.785.4578.

PLEASE NOTE: You must register online. This informational panel is not a registration form.

Register online, at cme.yale.edu

online registration instructions:

1. Go to “Find/Register for CME”

2. Visit “Live Courses”

3. Scroll down and select “34th Annual Ella T. Grasso Memorial Conference” 4. Click “Register” in order to proceed

Please note: You will be required to login or create a profile to register

OR, Please scan the image at right (QR Code) with your Smartphone or Tablet to be directed to the conference homepage and proceed with Step 4.

YaleCMECONTINUING MEDICAL EDUCATION

34TH ANNUAL ELLA T. GRASSO MEMORIAL CONFERENCE

LOCATIONYale West Campus

100 West Campus DriveBuilding 800 - Conference Center

Orange, CT

WEDNESDAY11 - 28 - 2018

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Learning Objectives

course directorPeter E. Schwartz MD John Slade Ely Professor of Obstetrics, Gynecology and Reproductive Sciences Vice Chair, Gynecology Yale School of Medicine

Masoud Azodi MD Professor of Obstetrics, Gynecology, and Reproductive Sciences Director of Minimally Invasive and Robotic Surgery Director of Minimally Invasive Gynecologic Surgery Fellowship

Charles Fuchs MD, MPH Richard Sackler and Jonathan Sackler Professor of Medicine (Medical Oncology)Director, Yale Cancer Center and Physician-in-Chief, Smilow Cancer Hospital

Melinda Irwin PhD, MPH Professor of Epidemiology (Chronic Diseases)Associate Director (Population Sciences), Yale Cancer Center Co-Program Leader, Cancer Prevention and Control, Yale Cancer Center Deputy Director (Public Health), Yale Center for Clinical Investigation

Babak Litkouhi MD, FACOG, FACS Assistant Professor of Obstetrics, Gynecology, and Reproductive Sciences

Gulden Menderes MD Assistant Professor Obstetrics and Gynecology in the Division of Gynecologic Oncology

This course will enable participants to:

~ Discuss the role of obesity and cancer

~ Utilize new developments in the management of malignancies of the female reproductive tract

~ Evaluate advances in precision medicine for the treatment of gynecological cancers

Conference Faculty subject to change Conference Schedule subject to change

yale school of medicine conferenceThis conference is being held at Yale West Campus Conference Center, 100 West Campus Drive,Building 800, Orange, CT.

The 34th Annual Ella T. Grasso Memorial Conference will review significant updates on a variety of topics of importance to gynecologists, oncologists, and other relevant specialties. Topics will include new developments in the management of pre-malignancies and malignancies of the female reproductive tract, advances in precision medicine for the treatment of gynecologic cancers, and updates on the link between obesity and cancer.

7:00 am Registration and Continental Breakfast

8:00 am Welcome and Opening Remarks Peter E. Schwartz MD

Session I: Obesity and Cancer

8:10 am GI Cancer Charles Fuchs MD, MPH

8:40 am Breast and Ovarian Cancer Melinda Irwin PhD, MPH

9:10 am Endometrial Cancer Babak Litkouhi MD, FACOG, FACS

9:35 am Discussion / Question and Answer

9:50 am Refreshment Break

Session II: New Developments in The Management of Pre-Malignancies and Malignancies of The Female Reproductive Tract

10:15 am Nonsurgical Treatment of CIN 2 and 3 Sangini Sheth MD, MPH

10:45 am Circulating Tumor DNA and Ovarian Cancer John A. Martignetti MD, PhD

11:15 am Advances in Minimally Invasive Surgery (MIS) for the Treatment of Gynecologic Cancer Gulden Menderes MD

11:45 am Discussion / Question and Answer

12:00 pm Working Lunch MIS Films and Discussion Masoud Azodi MD and Gulden Menderes MD

Session III: Advances in Precision Medicine for the Treatment of Gynecologic Cancers

1:20 pm Advances in Endometrial Cancer Therapy Alessandro D. Santin MD

1:50 pm PARP Inhibitor Combinations in Ovarian Cancer Elena Ratner MD

2:20 pm Discussion / Question and Answer

2:30 pm Adjourn

The Yale School of Medicine designates this live activity for a maximum of 5.25 AMA PRA Category 1 Credits™.

This conference is held in memory of Ella T. Grasso, born Ella Rose Tambussi. During the Second World War she served as assistant director of research for the War Manpower Commission of Connecticut. She became the first woman to be elected Floor Leader of the House in 1955 and was also the first woman to chair the Democratic State Platform Committee, serving from 1956-68. In 1974 her winning streak was extended when the people of Connecticut chose her as the nation’s first woman to be elected governor in her own right—the capstone of a long and successful career dedicated to public service, effective government and the democratic process. In 1980, Grasso was diagnosed with ovarian cancer; ill-health led to her resignation in December of that year. She passed away in Hartford, CT on February 5, 1981.

The conference was originally established by Drs. Steven Curry and Peter E. Schwartz, as a joint effort between their two institutions, the University of Connecticut and Yale University, to honor Governor Grasso and to provide the latest information regarding the care of Gynecologic cancer patients to the physicians of Connecticut. It remains one of the longest running cooperative programs involving these two institutions.

yale school of medicine facultyElena Ratner MD Associate Professor of Obstetrics, Gynecology, and Reproductive Sciences Co-Chief, Section of Gynecologic Oncology

Alessandro D. Santin MD Professor of Obstetrics, Gynecology, and Reproductive Sciences Disease Aligned Research Team Leader, Gynecologic Oncology Program, Yale Cancer Center Co-Chief, Section of Gynecologic Oncology

Sangini Sheth MD, MPH Assistant Professor of Obstetrics, Gynecology, and Reproductive Sciences Associate Medical Director & Director of Colposcopy and Cervical Dysplasia, Women’s Center, Yale New Haven Hospital

visiting facultyGiampiero (John) A. Martignetti MD, PhD Professor of Genetics and Genomic Sciences Professor of Oncological Sciences Professor of Obstetrics, Gynecology and Reproductive Science Professor of Pediatrics Icahn School of Medicine at Mount Sinai