21 feb 2018 cv r h khan - aligarh muslim university · ankita: “studies on the binding of...
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1.
2.
3.
4.
EDUCAT
Ph.D.
M.Phil.
M.Sc.
B. Sc
POSITIO
Present Pos
Associate P
Reader, Inte
2008.
Lecturer, In
March 2005
TIONAL
ON HELD
ition: Profess
Professor (Apr
erdisciplinary
nterdisciplina
5.
QUALIFI
From Interd
India in 199
Thesis: "Pu
lectin."
From Interd
India in 199
Dissertation
polysacchar
From Interd
India in 198
From Luckn
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sor (27/4/201
ril 2008-26Ap
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Biotechnolo
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AMU, Aligarh
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5. Project Associate, worked on "Cloning, Expression and Purification of Ovine Growth
Hormone" DBT sponsored project at National Institute of lmmunology, New Delhi, India
from October 1996-October 1997.
6. Lecturer, Interdisciplinary Biotechnology Unit, AMU, Aligarh, India from March 1993-
September 1995.
7. Visiting fellow:
(a) University of Michigan, Ann Arbor, U.S.A. (2000)
(b) University College of London, U.K. (2011)
(c) Visiting Professor, King Saud University, Riyadh, Saudi Arabia (2013)
ACADEMIC HONOURS/AWARDS/SCHOLARSHIPS
1. Junior Research Fellowship awarded from the Council of Scientific and
Industrial Research, Govt. of India (1989-1991)
2. Senior Research Fellowship awarded from the Council of Scientific and
Industrial Research, Govt. of India (1992-1993)
3. Qualified Graduate Aptitude Test in Engineering with a percentile of
92.48 (1989)
4. Best Poster award at 38th Annual Meeting of the Association of
Microbiologists of India & Conference on Microbes in Sustainable
Development held at Jamia Mi1lia Islamia Campus, New Delhi, 12-14
December, 1997 for the Poster entitled" Recombinant ovine growth hormone
expression in high cell density fed-batch culture of E.coli".
5. Awarded BOYSCAST Fellowship for the year 2000, to work at University
of Michigan, Ann Arbor, USA with Prof. I.J.Goldstein.
6. Awarded INSA Visiting Fellowship 2001, to work at A.I.I.M.S, New Delhi
with Prof. T.P. Singh.
7. Awarded SERC Visiting Fellowship 2002 to work at I.I.Sc, Bangalore with
Prof. A. Surolia.
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8. Awarded the Young Muslim Scientist Award (YMSA)-2002 by the Muslim
Association for the Advancement of Science (MAAS), Aligarh.
9. Best Poster award at National Syposium on Biophysics “Biophysics in
Medicine and Biology” under the aegis of Indian Biophysical society,
organized by ‘The Department of Biophysics’; Punjab University
Chandigarh, November 15-17, 2007.
10 Awarded Commonwealth Fellowship for the year 2011, to work at
University College of London, U.K.
11. Received “Best Researcher Award of the University” for the year 2015.
A.M.U, Aligarh, U.P.
12. F E L L O W of Biotechnology research society, 2017.
13. Received “Mid-Career Award” from UGC, Govt. of India, 2018
14. Selected as “Bentham Ambassador” of Bentham Science Publishers.
PAPER REVIEWING EXPERIENCE
Editor
1. International Journal of Biological Macromolecules (IJBM)
2. Protein Peptide Letters
In the panel of Editorial Board members:
1. PLoS One (Academic Editor)
3. Current Protein Peptide Science
4. Journal of Biophysics
5. Protein Peptide Letters
6. Journal of Biomedicine & Biotechnology
7. Journal of Biophysical Chemistry
8. Journal of Protein & Proteomics
9. Journal of Proteomics & Bioinformatics
Reviewed papers submitted for publication to the following journals:
1. Biochemistry (USA)
2. Archives of Biochemistry and Biophysics
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3. Biochimica et Biophysica Acta
4. The International Journal of Biochemistry & Cell Biology
5. Comparative Biochemistry and Physiology
6. Indian Journal of Clinical Biochemistry
7. International Journal of Biological Macromolecules
CONTRIBUTION OF CHAPTER TO A BOOK OR BOOK:
1. A few studies done in solvent mediated unfolding of serum albumins: Folding intermediates, Aggregation and unfolding. (http://www.amazon.com/studies-solvent-mediated-unfolding-albumins/dp/3659127051).
2. Recombinant polypeptides in Therapeutics in “Specialty Polymers” by I.K. International Publishing house Pvt. Ltd. (2007). Chapter contribution. (http://www.abebooks.co.uk/book-search/isbn/8188237655/page-1/).
3. Chapter contributed to e- series of book titled “Advances in Protein and Peptide Sciences, Vol.1,2013,833-867”. (http://ebooks.benthamscience.com/book/9781608054879/chapter/117205/)
4. Chapter “Protein folding and aggregation: a revisit of basic concept” contributed in e-book entitled Proteostasis and Chaperone Surveillance by Singh RL, Springer India 2015. (http://www.springer.com/in/book/9788132224662)
5. Chapter “Protein Structure and Function” contributed in e-book entitled Basic Biochemistry by Wahid Ali Khan Austin Publishing group 2017 (http://austinpublishinggroup.com/ebooks/basic-biochemistry/chapters/BBC-17-12.pdf)
6. Chandel, Tajalli Ilm, Mohsin Vahid Khan, and Rizwan Hasan Khan. "Impact of Osmolytes in Conformational Modulation of Protein and Its Applications in Biotechnology." In Cellular Osmolytes, pp. 143-160. Springer, Singapore, 2017.
PROFESSIONAL SOCIETY MEMBERSHIP
1. Indian Biophysical Society, India (Life member) 2. Society of Biological Chemists, India 3. Life member of Biotech Research Society of India
RESEARCH EXPRIENCE
1. Pre-doctoral
The work of my Ph.D. thesis deals with the isolation, purification and physico-
chemical study on pigeon pea lectin. The lectin was purified by salt precipitation
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followed by affinity chromatography. The purity and molecular weight of the
lectin was determined by gel filtration and SDS-PAGE. The UV-CD spectra of
lectin suggest that the predominant secondary structure is β- pleated sheet. The
saccharide binding specificity was investigated by hapten-inhibition of
hemagglutination or glycoconjugate precipitation. The presence of various
ionizable groups was determined by hydrogen-ion titration. Numbers of
phenoxyl groups present in lectin were also determined by spectrophotometric
method. The effect of metal ions on carbohydrate binding activity of lectin was
investigated in detail.
2. Post-doctoral
This involves the scale up of biological processes for the production of
recombinant proteins from E.coli, process optimization, downstream operation
for protein purification. Also, optimization of solubilization process for
recombinant proteins was made in order to refold them to their native structure.
3. PRESENT WORK
Currently involved in the following aspects of Structural Biology:
1. Protein stability, Structure and Function
2. Amyloid induction and inhibition
3. Characterization of folding intermediates of proteins at low pH.
4. Interaction of lectin with rhizobia.
5. Purification and physico-chemical characterization of lectin from different
sources.
6. Protein aggregation and misfolding
EXPERIENCE OF GUIDING RESEARCH ( PhD)
1. Mr. Mateen Ahmad Khan: “Studies on the interaction of tetracycline with
biological macromolecules” (Completed) 2001
2. Ms. Soghra Khatun Haq: “Isolation and Biochemical characterization of
protein-proteinase inhibitors from Cajanus cajan and phaseolus aureus”
(Completed) 2004. Presently she is Lecture at Deptt. of Biochemistry, Faculty
of Medicine/Medical Technology, Omar-al-Mukhtar University, Libya.
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3. Ms. Aabgeena Naeem: “Purification of lectin from Cajanus cajan roots and
Clitoria ternatea seeds and studies on the interaction of lectin with
polysachharides” (Completed) 2006. She is Assistant Professor at Department
of Biochemistry, A.M.U., Aligarh, India.
4. Mr. Basir Ahmad: “Studies on folding intermediates of multi-domain and
multimeric proteins. (Completed)2006. Presently he is Associate Professor at
Centre for Excellence in Basic Sciences, University of Mumbai, Maharashtra,
India.
5. Mrs. Farah Naseem: “Characterization of folding intermediate states of some
legume lectins and glycoproteins. (Completed)2007. Presently in company.
6. Mr. M. T. Ashraf: “Spectroscopic characterization of folding intermediates of
various proteins and purification of lectin from Trigonella foenumgraecum”
(Completed)2008. He is Assistant Professor at Gautam Buddha Technical
University, Greater NOIDA, India.
7. Ms. Sadaf Fatima” “Characterization of folding intermediates of monomeric and
dimeric proteins” (Completed)2008. She is Assistant Professor at Department
of Bioscience, Jamia Millia Islamia, New Delhi, India.
8. Mr. Priyankar Sen: “Characterization of folding intermediates of mammalian
serum albumin” (Completed)2009. He is Assistant Professor at CBST, VIT
University, India.
9. Mrs. Ankita: “Studies on the binding of endogenous and exogenous ligands to
human serum albumin” (Completed)2010. Presently working as Staff Scientist
IV at National Institute of Immunology, New Delhi India.
10. Mr. Ejaz Ahmad: “Conformational and binding studies of single and multy
chain proteins and lectins” (Completed) 2012.Presently working as
Postdoctoral Research Fellow at University of Toledo, U.S.A.
11. Mr. Gulam Rabbani: “Characterization of folding intermediates of microbial
lipases from psychrophilic, mesophilic and thermophilic origin” (Completed)
2013. Presently he is Post-doctoral fellow Department of Medical
Biotechnology, Yeung Nam University, Korea.
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12. Mr. Javed Masood Khan: “Elucidating the mechanism of Protein aggregation
and Conformational stability of some proteins” (Completed) 2013. Presently he
is Post-doctoral research fellow at at King Saud University, Saudi Arabia
13. Mrs. Atiyatul Qadeer: Studies on folding and aggregation behavior of plant
cysteine proteases. (Completed -2014). Presently working as QC Analyst,
Analytical Research and Development at Apotex Inc.
14. Ms. Nida Zaidi: Biophysical insight into interaction of ligands to monomeric
proteins and associated conformational alterations. (Completed -2014).
Presently working as UGC Post-doctoral fellow at Interdisciplinary
Biotechnology Unit.
15. Mr. Sumit Kumar Chaturvedi: Ligand binding and conformational study in
some proteins (Completed-2014). Presently working as Post-doctoral fellow at
NIH Bethesda, U.S.A
16. Mr. Mohd. Ishtikhar: Biophysical investigation of ligand induced
conformational changes and aggregation of monomeric proteins (Completed
2015). Presently working as Post-doctoral fellow in IIT (Mumbai), India.
17. Mr. Mohd Rehan Ajmal: Effect of ligand on conformation changes and
aggregation behavior of proteins (Completed 2016). Presently working as
Assistant Professor at Tabuk University, Saudi Arabia.
18. Mr. Masihuzzaman: Biophysical studies on aggregation and inhibition of some
proteins by various molecules (Completed 2017)
19. Mr. Mohsin Vahid Khan: Studies on the role of various additives exhibiting
aggregation or anti- aggregation effect on the proteins (Completed 2017)
20. Mr. Parvez Alam: Studying the effect of small molecules to combat amyloid
formation in some proteins (Completed, 2017) Presently working as Post-
doctoral fellow in IIT (Delhi), India.
21. Mrs. Saima Nusrat: Biophysical insight into interaction and aggregation
inhibition of proteins by small molecules (Completed, 2017).
22. Two candidates have completed MD (Medicine) under my co-supervision.
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23. Guided thirty MSc students in their projects required in partial fulfillment for
the award of MSc. degree at Interdisciplinary Biotechnology Unit, A.M.U,
Aligarh.
Research Grants Received
1. Council of Scientific and Industrial Research grant for “Studies on the
interaction of Cajanus Cajan lectin with rhizobia and purification of lectin
from Clitoria ternatea” (2000-2004). Grant No. 38/978/99 EMR II
2. University Grants Commission grant for “Purification and characterization
of lectin from “Trigonella foenum graecum” (2002-2004). Grant No. 3-
12/2002 SR II
3. Department of Science and Technology grant for “Characterization of
molten globule states of Cajanus cajan lectin” (2005-2008)
Grant No. SR/SO/BB-39/2004
4. Council of Scientific and Industrial Research grant for “Neutral transition
of Human Serum albumin and its impact on drug delivery and elimination of
endogenous toxins” (2006-2009) Grant No. 37(1278)/06/EMR-II
5. University Grants Commission grant for “Characterization of folding
intermediate states of microbial Lipases” (2007-2010). Grant No. 32-
543/2006 (SR)
6. Department of Biotechnology grant for “Characterization of Molten
Globule States of Banana Lectin” (2007-2010). Grant No. BT/PR
8473/10/521/2006
7. Indian Council of Medical Research grant for “Studies on the mode of
interaction of Drugs with Human Serum Albumin” (2009-2012).
Grant No.58/14/06-BMS
8. Department of Biotechnology grant for “Conformational and drug binding
studies of alpha-1 acid glycoprotein” (2010-2012).
Grant No. BT/PR 13194/10/742/2009
9. Council of Scientific and Industrial Research grant for “pH dependent
stability and effect of chaotropic agent on con-albumin” (2010-2012).
Grant No. 37(1456)/10/EMR-II
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10. University Grants Commission grant for “Spectroscopic studies on acid
induced unfolding of Egyptian cobra venom and that of Indian origin species.
(2010-2012)Grant No. 39-277/2010 (SR)
11. Department of Science and Technology “Characterization of folding
intermediates of chymopapain.” Grant No.SR/SO/BB-0018/2011
12. Department of Science and Technology “Exploring the anti amyloidogenic
behavior of anti-tuberculosis drug-possible implications in treatment of
Alzheimer’s disease. (2017-ongoing) Grant No37(1676)/17/EMR-II.
PROFESSIONAL EXPERIENCE
1. Well versed in isolation, purification and characterization of recombinant
proteins as well as novel proteins.
2. Experienced in handling and operation of analytical and process scale
chromatography ex: Bio-pilot system, affinity chromatography, ion-
exchange chromatography, exclusion chromatography and HPLC.
3. Expertise in following techniques:
Spectrophotometry
Spectrofluorometry
Circular Dichroism
Ultra-Centrifugation
Viscosity
Isothermal Titration Calorimetry
Differential Scanning Calorimetry
NAME AND ADDRESS OF ACADEMIC REFREES
1. Dr. Dinkar M. Salunke, Director of ICGEB, New Delhi-110067.Email:
2. Prof. Rajiv Bhat, Centre for Biotechnology, Jawaharlal Nehru University,
New Delhi-110067. Email: [email protected]
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3. Dr. Y.D. Sharma, Department of Biotechnology, AIIMS, New Delhi 110
029. Email: [email protected]
4. Prof. Asif Ali, Department of Biochemistry, JNMC, AMU, Aligarh. Email:
[email protected], [email protected].
Intellectual Property
1. Indian Provisional Patent Application No. 401/DEL/2013.
Rabbani G, Ahmad E, Khan RH, Kumar M. entitled “Aqueous organic
solvent-induced conformational alterations and amyloid formation in lipase”.
2. Indian Provisional Patent Application No. 1080/DEL/2013.
Rabbani G, Ahmad E, Khan MV, Ahmad A, Khan RH, Kumar M. entitled
“A process for inducing conformational alterations in Thermomyces
lanuginosa lipase”
ARTICLES FALL AMONGS TOP TEN OF JOURNALS
1. Panda, A.K., Khan, R.H., Rao, K.B. and Totey, S.M. Kinetics of inclusion
body production in batch and high cell density fed-batch culture of Escherichia
coliexpressing ovine growth hormone. (1999) J. Biotechnol. 75(2-3), 161- 172.
2. Ahmad, B., Parveen, S. and Khan, R.H. Effect of albumin conformation on the
binding of ciprofloxacin to human serum albumin: a novel approach directly
assigning binding site. (2006) Biomacromolecules 7 (4), 1350-1356
3. Haq, S.K., Atif, S.M. and Khan, R.H. Protein proteinase inhibitor genes in
combat against insects, pests and pathogens: natural and engineered
phytoprotection. . (2004) Arch. Biochem. Biophys. 431(1), 145-159.
4. Zahir, F., Rizwi, S.J., Haq, S.K. and Khan, R.H. Low dose mercury toxicity
and human health. (2005) Environ. Toxicol. Pharmacol. 20 (2), 351-360.
5. Salahuddin P, Rabbani G, Khan RH. The role of advanced glycation end
products in various types of neurodegenerative disease: a therapeutic approach.
Cell Mol Biol Lett (2014). DOI: 10.2478/s11658-014-0205-5.
6. Alam P, Chaturvedi SK, Siddiqi MK, Rajpoot RK, Ajmal MR, Zaman
M, Khan RH Vitamin k3 inhibits protein aggregation: Implication in the
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treatment of amyloid diseases. Sci Rep. 2016 May 27;6:26759. doi:
10.1038/srep26759.
LIST OF RESEARCH PUBLICATIONS
1. Salahuddin, A. and Khan, R.H. Hydrogen ion equilibria of Cajanus Cajan
lectin. (1998) J. Protein Chem. 17 (3), 181-185.
2. Khan, R.H., Rao, K.B., Eshwari, A.N., Totey, S.M. and Panda, A.K.
Solubilization of recombinant ovine growth hormone with retention of native-
like secondary structure and its refolding from inclusion bodies of Escherichia
coli. (1998) Biotechnol. Prog. 14 (5), 722-728.
3. Ahmad, S., Khan, R.H. and Ahmad, A. Physicochemical characterization of
Cajanus cajan lectin: effect of pH and metal ions on lectin carbohydrate
interaction. (1999) Biochim.Biophys. Acta. 1427 (3), 378-384.
4. Panda, A.K., Khan, R.H., Rao, K.B. and Totey, S.M. Kinetics of inclusion
body production in batch and high cell density fed-batch culture of
Escherichia coliexpressing ovine growth hormone. (1999) J. Biotechnol.
75(2-3), 161- 172.
5. Panda, A.K., Khan, R.H., Mishra, S., Rao, K.B. and Totey, S.M. Influence of
Yeast extract on specific cellular yield of ovine growth hormone during fed-
batch fermentation of E.coli. (2000) Bio. Process Engg. 22, 379- 383.
6. Khan, F., Khan, R.H. and Muzammil, S. Alcohol-induced versus anion-
induced states of alpha chymotryposinogen A at low pH. (2000) Biochim.
Biophys. Acta1481 (2), 229-236.
7. Khan, R.H. and Shabnum, M.S. Effect of sugars on rabbit serum albumin
stability and induction of secondary structure. (2001) Biochemistry
(Mosc.)66 (9), 1042-1046.
8. Naeem, A., Khan, R.H., Vikram, H. and Akif, M. Purification of Cajanus
cajanroot lectin and its interaction with rhizobial lipopolysaccharide as
studied by different spectroscopic techniques. (2001) Arch. Biochem.
Biophys.396 (1), 99-105.
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9. Haq, S.K., Rasheedi, S. and Khan, R.H. Characterization of a partially folded
intermediate of stem bromelain at low pH. (2002) Eur. J. Biochem. 269 (1),
47-52.
10. Khan, R.H. Involvement of carboxyl and phenoxyl groups in Cajanus
cajanlectin - sugar interaction: Interpretation of titration curve. (2002) J.
Protein Chem. 21 (2), 105-110.
11. Gupta, P., Khan, R.H. and Saleemuddin, M. Binding of antibromelain
monomeric Fab' improves the stability of stem bromelain against inactivation
(2003) Biochim. Biophys. Acta. 1646 (1-2), 131-135.
12. Haq, S.K., Ahmad, M.F. and Khan, R.H. The acid-induced state of glucose
oxidase exists as a compact folded intermediate. (2003) Biochem. Biophys.
Res. Commun. 303 (2), 685-692.
13. Gupta, P., Khan, R.H. and Saleemuddin, M. Trifluoroethanol-induced
"molten globule" state in stem bromelain. (2003) Arch. Biochem. Biophys.
413(2), 199-206.
14. Naseem, F., Khan, R.H., Haq, S.K. and Naeem, A. Characterization of
molten globule state of fetuin at low pH. (2003) Biochim. Biophys. Acta
1649 (2), 164-170.
15. Haq, S.K. and Khan, R.H. Characterization of a proteinase inhibitor from
Cajanus cajan (L.) (2003) J. Protein Chem. 22 (6), 543-554.
16. Rasheedi, S., Haq, S.K. and Khan, R.H. Guanidine hydrochloride
denaturation of glycosylated and deglycosylated stem bromelain. (2003)
Biochemistry (Mosc.) 68 (10),1097-1100.
17. Naseem, F. and Khan, R.H. Effect of Ethylene glycol and Polyethylene
glycol on acid unfolded state of trypsinogen. (2003) J. Protein Chem.22 (7-
8), 677-682.
18. Gupta, P., Khan, R.H. and Saleemuddin, M. Induction of ‘molten globule’
like state in acid denatured state of unmodified preparation of stem bromelain:
Implication of disulphides in protein folding. (2003) Int. J. Biol. Macromol.
33 (4-5),167-174.
19. Khan, R.H., Rasheedi, S. and Haq, S.K. Effect of pH, temperature and
alcohols on the stability of glycosylated and deglycosylated stem bromelain.
(2003) J. Biosc. 28 (6), 709-714.
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20. Ahmad, B., Khan, M.K.A., Haq, S.K. and Khan, R.H. Intermediate formation
at lower urea concentration in 'B' isomer of human serum albumin: a case
study using domain specific ligands. (2004) Biochem. Biophys. Res. Comm.
314 (1), 166-173.
21. Naeem, A., Akram, M. and Khan, R.H. Conformational states of
trifluoroacetic acid treated cytochrome c in the presence of salts and alcohols.
(2004) Protein J. 23 (3), 185-195.
22. Naseem, F., Ahmad, B., Ashraf, M.T. and Khan, R.H. Molten globule-like
folding intermediate of asialofetuin at acidic pH. (2004) Biochim. Biophys.
Acta 1699 (1-2), 191-199.
23. Ahmad, B., Kamal, M.Z. and Khan, R.H. Alkali-induced conformational
transition in different domains of bovine serum albumin (2004) Protein Pept.
Lett. 11 (4), 307-315.
24. Naeem, A. and Khan, R.H. Characterization of molten globule state of
cytochrome C at alkaline, native and acidic pH induced by butanol and SDS.
(2004) Int. J. Biochem. Cell Biol. 36 (11), 2281-2292.
25. Naseem, F. and Khan, R.H. Fluoroalcohol-induced stabilization of the α-
helical intermediates of lentil lectin: Implication for non-hierarchical lectin
folding. (2004) Arch. Biochem. Biophys. 431(2), 215-223.
26. Naeem, A. Khan, K.A. and Khan, R.H. Characterization of a partially folded
intermediate of papain induced by fluorinated alcohols at low pH. (2004)
Arch. Biochem. Biophys.432 (1), 79-87.
27. Haq, S.K., Rasheedi, S., Sharma, P., Ahmad, B. and Khan, R.H. Influence of
salts and alcohols on the conformation of partially folded state of stem
bromelain at low pH. (2005) Int. J. Biochem. Cell Biol. 37 (2), 361-374.
28. Ashraf, M.T and Khan, R.H. Effect of metal ions and EGTA on the optical
properties of concanavalin A at alkaline pH (2005) Protein Pept. Lett. 12 (2),
203-206.
29. Haq, S.K. and Khan, R.H. Spectroscopic analysis of thermal denaturation of
Cajanus cajan proteinase inhibitor at neutral and acidic pH. (2005) Int. J.
Biol. Macromol. 35 (1-2), 111-116.
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30. Khan, R.H., Naeem, A. and Baig, M.A. Spectroscopic studies on the
protective effect of specific sugar on concanavalin A at acidic, neutral and
alkaline pH. (2005) Cell Mol. Biol. Letts. 10 (1), 61-72.
31. Ahmad B, Ankita and Khan, R.H. Urea induced unfolding of F isomer of
human serum albumin: A case study using multiple probes. (2005) Arch.
Biochem. Biophys. 437(2), 159-167.
32. Naseem, F. and Khan, R.H. Characterization of common intermediate of pea
lectin in the folding pathway induced by TFE and HFIP. (2005) Biochim.
Biophys. Acta 1723 (1-3), 192-200.
33. Ahmad, B., Ahmed, M.Z., Haq, S.K. and Khan, R.H. Guanidine
Hydrochloride denaturation of human serum albumin originates by local
unfolding of some stable loops in domain III. (2005) Biochim. Biophys. Acta
1750 (1), 93-102.
34. Naeem, A. Khan, A. and Khan, R.H. Partially folded intermediate state of
concanavalin A retains its carbohydrate binding specificity (2005) Biochem.
Biophys. Res. Commun. 331 (4), 1284-1294.
35. Haq, S.K. and Khan, R.H. Effect of detergents and hexafluoroisopropanol on
a non-helical and a helical protein inhibitor. (2005) Int. J. Biol. Macromol.
36 (1-2), 47-53.
36. Haq, S.K., Atif, S.M. and Khan, R.H. Biochemical characterization, stability
studies and terminal sequence of a bi-functional inhibitor from Phaseolus
aureus (Mung bean). (2005) Biochimie 87 (12), 1127-1136.
37. Kaur, M., Singh, K., Rup, P.J., Saxena, A.K., Khan, R.H., Ashraf, M.T.,
Kamboj, S. S. A tuber lectin from Arisaema helleborifolium Scholt with anti-
insect activity against melon fruit fly, Bactrocera cucurbitae (Coquillett) and
anti-cancer effect on human cancer cell lines. (2006) Arch. Biochem. Biophy.
445 (1), 156-165.
38. Zahir, F., Rizvi, S. J., Haq S. and Khan, R. H. Effect of methyl mercury
induced free radical stress on nucleic acids and protein: Implications on
cognitive and motor functions. (2006) Ind. J. Clin. Biochem. 21 (2), 149-152.
39. Naeem, A., Khan R.H. and Saleemuddin, M. Single step immobilized metal
ion affinity precipitation/chromatography based procedures for purification of
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concanavalin A and Cajanus cajan mannose specific lectin.(2006)
Biochemistry (Mosc.) 71 (1), 56-59.
40. Gupta, P., Saleemuddin, M. and Khan, R.H. Hydrophobic interactions are
prevalent forces between bromelain: Fab’ complexes. (2006) Biochemistry
(Mosc.) 71 Suppl 1, 31-37.
41. Ahmad, B., Parveen, S. and Khan, R.H. Effect of albumin conformation on
the binding of ciprofloxacin to human serum albumin: a novel approach
directly assigning binding site. (2006) Biomacromolecules 7 (4), 1350-1356
42. Ahmad, B., Ansari, M.A., Sen, P. and Khan, R.H. Low versus high molecular
weight poly (ethylene glycol) induced states of stem bromelain at low pH:
stabilization of molten globule and unfolded states. (2006) Biopolymers 81
(5), 350-359.
43. Gull N., Kumar S., Ahmad B., Khan, R.H. and Kabir -ud-Din. Influence of
urea additives on micellar morphology/protein conformation. (2006) Colloids
Surf B Biointerfaces. 51 (1), 110-115.
44. Dev, S., Khan, R.H. and Surolia A. 2,2,2 Trifluoroethanol induced structural
change of peanut agglutinin at different pH. A comparative account. (2006)
IUBMB Life 58 (8), 473-479.
45. Naeem, A., Fatima, S. and Khan, R.H. Characterization of partially folded
intermediates of papain in presence of cationic, anionic, and nonionic
detergents at low pH. (2006) Biopolymers83 (1), 1-10.
46. Ahmad, B. and Khan, R.H. Studies on the acid unfolded and molten globule
states of catalytically active stem bromelain: A comparison with catalytically
inactive form. (2006) J. Biochem 140 (4), 501-508.
47. Naeem A., Ashraf, M.T., Akram, M., Khan, R.H. Comparative study of
effects of polyols, salts, and alcohols on trichloroacetic acid-induced state of
cytochrome C, Biochemistry (Mosc). (2006) 71 (10), 1101-1109.
48. Fatima S., Ahmad, B. and Khan, R.H. Fluoroalcohols induced unfolding of
Succinylated Con A: native like beta structure in partially folded intermediate
and alpha helix in molten globule like state. (2006) Arch. Biochem. Biophys.
454 (2), 170-180.
16
49. Naeem, A., Ahmad, E., Ashraf, M.T. and Khan, R.H. Purification and
characterization mannose/glucose-specific lectin from seeds of Trigonella
foenumgraecum (2007) Biochemistry (Mosc.)72 (1), 44-48.
50. Ahmad, B., Shamim, T.A., Haq, S.K. and Khan, R.H. Identification and
characterization of functional intermediates of stem bromelain during urea and
guanidine hydrochloride unfolding. (2007) J. Biochem. 141 (2), 251-259.
51. Gull N., Sen P, Kabir –ud-Din and Khan, R.H. Effect of physiological
concentration of urea on the conformation of human serum albumin. J.
Biochem (2007) 141(2), 261-268.
52. Fatima, S., Ahmad, B., and Khan, R.H. Native like tertiary structure in the
Mucor miehei lipase molten globule state obtained at low pH (2007) IUBMB
Life 59 (3), 179-186.
53. Hameed M, Ahmad B, Fazili K.M. and Khan, RH. Different Molten Globule-
like Folding Intermediates of Hen Egg White Lysozyme Induced by High pH
and tertiary butanol. (2007) J. Biochem. 141 (4), 573-583.
54. Fatima S. and Khan, R.H. Effect of polyethylene glycols on function and
structure of thiol proteases. (2007) J. Biochem. 142 (1), 65-72.
55. Naeem, A., Haque S. and Khan, R.H. Purification and characterization of a
novel beta-D Galactosides-specific lectin from Clitoria ternatea. (2007)
Protein J.26 (6), 403-413.
56. Naseem, F. and Khan, R.H. Transition of a compact intermediate state of pea
lectin under the influence of different molecular weight polyethylene glycols
(2007) Protein J. 26 (6), 415-421.
57. Ahmad, E., Naeem, A. and Khan, R.H. The minimal structural requirement of
concanavalin A that retains its functional aspects. (2007) J. Biochem. 142 (3),
307–315.
58. Fatima A., Husain, Q. and Khan, R.H. A novel peroxidase from bitter gourd
(Momordica charantia): Comparison of its stability with horseradish
peroxides. (2007) J. Mol: Cat B 47 (1-2), 66-71.
59. Naeem, A., Ahmad, E. and Khan, R.H. An alternate high yielding
purification method for Clitoria ternatea lectin. (2007) Int. J. Biol.
Macromol. 41 (4), 481-486.
17
60. Naseem, F. and Khan, R.H. Structural intermediates of acid unfolded Con A
in different co-solvents: fluoroalcohols and polyethylene glycols. (2008) Int.
J. Biol. Macromol.42 (2),158-165.
61. Naseem, F. and Khan, R.H. Pea Lectin in Alkaline Conditions: Formation of
molten globule-like intermediate and its structural and thermal studies under
the influence of hexa fluoroisopropanol. (2008) Protein Pept. Lett. 15 (6),
606-611.
62. Varshney, A., Ahmad, B. and Khan, R.H. Comparative Studies of unfolding
and binding of ligands to human serum albumin in presence of fatty acid:
Spectroscopic Approach. (2008) Int. J. Biol. Macromol. 42 (5), 483-490.
63. Fatima, S., Mishra, A., Sen, P. and Khan, R.H. Characterization of
fluoroalcohols induced intermediates of Mucor meihei lipase at low pH.
(2008) Protein Pept. Lett. 15 (4), 346-352.
64. Sen, P., Ahmad, B. and Khan, R. H. Formation of a molten globule like state
in bovine serum albumin at alkaline pH. (2008) Eur. Biophys. J. 37 (8),
1303-1308
65. Gupta, S., Mahmood, S., Khan, R.H. and Mahmood, A. Effect of Na+ ions on
pH-dependent conformational changes in brush border sucrose isomaltase in
mice intestine. (2008) Ind. J. Biochem. Biophys. 45 (6), 399-403.
66. Gull, N., Sen, P., Khan, R.H. and Kabir ud Din. Spectroscopic Studies on the
Comparative Interaction of Cationic Single-Chain and Gemini Surfactants
with human serum albumin. (2009) J. Biochem. 145 (1), 67-77.
67. Gull, N., Chodankar, S., Aswal, V.K., Sen, P., Khan, R.H. and Kabir-Ud-Din.
Spectroscopic studies on the interaction of cationic surfactants with bovine
serum albumin. (2009) Colloids Surf. B Biointerfaces. 69(1),122-128.
68. Hameed, M., Ahmad, B., Khan, R. H., Andrabi, K.I. and Fazili, K.M.
Tertairy butanol induced Amyloidogenesis of Hen egg White Lysozyme
(HEWL) is facilitated by aggregation prone alkali-induced molten globule like
conformational state.(2009) Protein Pept. Lett. 16 (1), 56-60.
69. Sen, P., Fatima, S. Khan, J.M. and Khan, R.H. How methyl cyanide induces
aggregation in all alpha proteins: A case study in four albumins. (2009) Int. J.
Biol. Macromol. 44(2), 163-169.
18
70. Fatima, S. and Khan R.H. Stability check of Succinylated Concanavalin A:
presence of functionally active conformational state. (2009) Protein Pept.
Lett. 16(4),423-429.
71. Gupta, S., Mahmood, S., Khan R.H., Mahmood, A. The inhibition of brush
border sucrase by polyphenols in mice intestine. (2010) Biosci Rep. 30(2),
111-117.
72. Sen P, Fatima S, Ahmad B and Khan R H. Interactions of thioflavin T with
serum albumins: Spectroscopic analyses. Spectrochimica Acta Part A 74
(2009) 94–99
73. Ahmad, B., Rathar, G.M., Varshney, A. and Khan, R.H. pH dependent urea
induced unfolding of stem bromelain: unusual stability against urea at neutral
pH. (2009) Biochemistry (Mosc.) 74(12),1337-1343.
74. Arjmand, F., Tewatia,P., Aziz, M. and Khan, R.H. Interaction studies of a
novel Co(II)-based potential chemotherapeutic agent with human serum
albumin (HSA) employing biophysical techniques.(2009) Med.Chem.Res.
19:794-807.
75. Naeem, A., Saleemuddin, M. and Khan, R.H. Compact Acid-Induced State of
Clitoria ternatea Agglutinin Retains Its Biological Activity.(2009)
Biochemistry (Mosc.).74(10),1088-1095.
76. Gull, N., Sen, P., Khan, R.H. and Kabir-Ud-Din. Interaction of bovine
(BSA), Rabbit (RSA), and Porcine (PSA) Serum albumins with cationic single
chain/Gemini surfactants: A Comparative Study. (2009) Langmuir.
25(19),11686-11691.
77. Sen, P., Iqbal, M.A., Fatima, S. and Khan, R.H. Methyl Cyanide induces
α to β-Transition and Aggregation at High Concentrations in E state of Human
Serum Albumin.(2010) Biochemistry (Mosc.).75(3), 367-374.
78. Ahmad, B., Islam, Z., Varshney, A.,and Khan, R.H. Stabilization of folding
Intermediate States from Alkaline Induced Unfolded State of Bovine Serum
Fetuin in Trifluoroethanol and Acetonitrile (2010) Protein Pept. Lett.17(5),
660-666.
79. Sen P., Ahmad, B., Rabbani G, Khan, R.H. 2, 2, 2-trifluroethanol induces
simultaneous Increase in Helicity and Aggregation in Alkaline Unfolded
19
State of Bovine Serum Albumin.(2010). Int. J. Biol. Macromol, 46(2), 250-
254.
80. Mir MA, Khan JM, Khan RH, Rather GM and Dar AA. Effect of spacer
length of alkanediyl-alpha,omega-bis(dimethylcetylammonium bromide)
gemini homologues on the interfacial and physicochemical properties of
BSA.(2010) Colloids Surf B Biointerfaces.77(1):54-9.
81. Ahmad, E., Rahman, S.K., Khan, J.M., Varshney, A., Khan, R.H. Phytolacca
americana lectin (Pa-2;pokeweed mitogen):an intrinsically unordered protein
and its conversion to partial order at low pH.(2010) Biosci Rep.30 (2), 125–
134.
82. Ahmad, B., Haq, S.K., Varshney, A., Moosavi-Movahedi, A.A. and Khan,
R.H. Effect of Trifluoroethanol on the Native and Acid Induced States of
Glucose Oxidase from Aspergillus niger. (2010) Biochemistry (Mosc.).75(4),
486-493.
83. Varshney, A., Ahmad, B. Rabbani, G.,Kumar, V., Yadav, S and Khan, R.H.
Acid Induced Unfolding of Didecameric Keyhole Limpet Hemocyanin:
Detection and Characterizations of Decameric and Tetrameric Intermediate
States (2010) Amino Acids 39(3):899-910.
84. Mir,M.A, Gull, N., Khan, J.M., Khan, R.H., Dar, A.A and G,M. Rather
.Interaction of Bovine Serum Albumin with Cationic Single Chain+Nonionic
and Cationic Gemini+Nonionic Binary Surfactant Mixtures (2010) J Phys
Chem B.114(9):3197-204.
85. Kumar S, Ahmad E, Mansuri MS, Kumar S, Jain R, Khan RH, Gourinath S,
Crystal structure and trimer-monomer transition of N-terminal domain of
EhCaBP1 from Entamoeba histolytica. (2010) Biophys J. 98(12):2933-42.
86. Priyadarshini M, Khan RH, Bano B. Physicochemical properties of thiol
proteinase inhibitor isolated from goat pancreas.(2010) Biopolymers.
93(8):708-17.
87. Arjmand F, Muddassir M, Khan RH. Chiral preference of l-tryptophan
derived metal-based antitumor agent of late 3d-metal ions (Co(II), Cu(II) and
Zn(II)) in comparison to d- and dl-tryptophan analogues: Their in vitro
20
reactivity towards CT DNA, 5'-GMP and 5'-TMP. (2010) Eur J Med
Chem.45(9): 3549-57
88. Ali MS, Khan JM, Aswal VK, Khan RH, Kabir-Ud-Din. Multi-technique
approach on the effect of surfactant concentrations on the thermal unfolding of
rabbit serum albumin: Formation and solubilization of the protein aggregates.
(2010) Colloids Surf B Biointerfaces.
89. Ahmad E, Fatima S, Khan MM, Khan RH. More stable structure of wheat
germ lipase at low pH than its native state. (2010) Biochimie 92: 885-93
90. Ali MS, Gull N, Khan JM, Aswal VK, Khan RH, Kabir-ud-Din. Unfolding of
rabbit serum albumin by cationic surfactants: surface tensiometry, small-angle
neutron scattering, intrinsic fluorescence, resonance Rayleigh scattering and
circular dichroism studies.(2010) J Colloid Interface Sci. 352:436-43 .
91. Naqvi Z, Khan RH, Saleemuddin M. A procedure for the purification of beta-
lactoglobulin from bovine milk using gel filtration chromatography at low
pH.(2010) Prep Biochem Biotechnol. 40: 326-36.
92. Bora H, Garg S, Sen P, Kumar D,Kaur P, Khan RH, Sharma YD,
Plasmodium vivax Tryptophan-Rich Antigen Pvtrag33.5 contains Alpha
Helical Structure and Multidomain Architecture. PLoS One (2011)
20:e16294.
93. Varshney A, Rehan M, Subbarao N, Rabbani G, Khan RH. Elimination of
endogenous toxin, creatinine from blood plasma depends on albumin
conformation: site specific uremic toxicity & impaired drug binding. PLoS
One. (2011) 28: e 17230.
94. Gull N, Mir MA, Khan JM, Khan RH, Rather GM, Dar AA. Refolding of
bovine serum albumin via artificial chaperone protocol using gemini
surfactants. J Colloid Interface Sci. (2011) 364:157-62.
95. Rabbani G, Ahmad E, Zaidi N, Khan RH. pH-dependent conformational
transitions in conalbumin (Ovotransferrin), a metalloproteinase from hen egg
white. Cell Biochem Biophys. (2011) 61:551-560.
96. Ahmad E, Sen P, Khan RH. Structural Stability as a Probe for Molecular
Evolution of Homologous Albumins Studied by Spectroscopy and
Bioinformatics. Cell Biochem Biophys. (2011) 61:313-25
21
97. Khan AB, Khan JM, Ali MS, Khan RH, Kabir-ud Din. Spectroscopic
approach of the interaction study of amphiphilic drugs with the serum
albumins. Colloids Surf B Biointerfaces. (2011) 87:447-53.
98. Ali MS, Anjum K, Khan JM, Khan RH, Kabir-ud-Din. Complexation
behavior of gelatin with amphiphilic drug imipramine hydrochloride as
studied by conductimetry, surface tensiometry and circular dichroism studies.
Colloids Surf B Biointerfaces. (2011) 1; 82:258-62.
99. Kumar P, Baidya B, Chaturvedi SK, KhanRH, Manna D, Mondal B. DNA
binding and nuclease activity of copper (II) complexes of tridentate ligands.
Inorganica Chimica Acta. (2011) 376;264-70.
100. Ahmad E, Rabbani G, Zaidi N, Singh S, Rehan M, Khan MM, Rahman SK,
Quadri Z, Shadab M, Ashraf MT, Subbarao N, Bhat R, Khan RH. Stereo-
selectivity of human serum albumin to enantiomeric and isoelectronic
pollutants dissected by spectroscopy, calorimetry and bioinformatics. PLoS
One. (2011) 6:e26186.
101. Rabbani G, Ahmad E, Zaidi N, Fatima S, Khan RH. pH induced molten
globule state of Rhizopus niveus lipase is more resistant against thermal and
chemical denaturation than its native state. Cell Biochem Biophys.
(2012)62:487-99.
102. Ahmad S, Moinuddin, Khan RH, Ali A. Physicochemical studies on
glycation induced structural changes in human IgG. IUBMB Life (2012)
64:151-156
103. Khan JM, Qadeer A, Chaturvedi SK, Ahmad E, Rehman AA, Gourinath S,
Khan RH. SDS can be utilized as an Amyloid Inducer: A Case Study on
Diverse Proteins. PLoS One. (2012); 7:e29694.
104. Mir MA, Khan JM, Khan RH, Dar AA, Rather GM. Interaction of
Cetyltrimethylammonium Bromide and Its Gemini Homologue
Bis(cetyldimethylammonium)butane Dibromide with Xanthine Oxidase. J
Phys Chem B(2012) 116: 5711-5718.
105. Ahmad E, Rabbani G, Zaidi N, Ahmad B, Khan RH. Pollutant-Induced
Modulation in Conformation and β-Lactamase Activity of Human Serum
Albumin. PLoS One(2012) 7:e38372.
22
106. Kumar M, Ahmad S, Ahmad E, Saifi MA, Khan RH. In Silico Prediction and
Analysis of Caenorhabditis EF-hand Containing Proteins. PLoS One.(2012);
7:e36770.
107. Khan AB, Khan JM, Ali MS, Khan RH, Kabir-ud-Din. Interaction of
amphiphilic drugs with human and bovine serum albumins. Spectrochim
Acta A. 2012 Jun 7; 97C:119-124.
108. Tabassum S, Al-Asbahy WM, Afzal M, Arjmand F, Khan R H. Interaction
and photo-induced cleavage studies of a copper based chemotherapeutic drug
with human serum albumin: spectroscopic and molecular docking study. Mol
Biosyst.(2012) 31; 8(9):2424-2433.
109. Sen, P, Ahmad E, Khan RH. At Very Low Concentrations Known
Chaotropes Act as Kosmotropes for the N and B Isoforms of Human Serum
Albumin. Biochem Cell Biol. (2013) 91: 72-78.
110. Kumar S, Ahmad E, Kumar S, Khan RH, Gourinath S. Flexibility of EF hand
motifs: structural and thermodynamic studies of Calcium Binding Protein-1
from Entamoeba histolytica with Pb2+, Ba2+, and Sr2+. BMC Biophys. 2012
5(1):15.
111. Naqvi Z, Ahmad E, Khan RH, Saleemuddin M. Non-native state of bovine
beta-lactoglobulin induced by acetonitrile: pH-dependent unfolding of the
two genetic variants A and B. Cell Biochem Biophys. (2013) 66: 175-185.
112. Qadeer A, Rabbani, G,Zaidi N,Ahmad E, Khan JM, Khan RH. 1-anilino-8-
naphthalene Sulfonate (ANS) is Not a Desirable Probe for Determining the
Molten Globule State of Chymopapain. PLoS One. (2012) 7: e50633.
113. Zaidi N, Ahmad E, Rehan M, Rabbani G, Ajmal MR, Zaidi Y, Subbarao N,
Khan RH. Biophysical insight into furosemide binding to human serum
albumin: astudy to unveil its impaired albumin binding in uremia. J
PhyChem B. (2013) 117(9):2595-604.
114. Kabir-ud-Din, Sharma G, Naqvi AZ, Chaturvedi SK, Khan RH. Ion-dipole
induced interaction between cationic gemini/TTAB and nonionic (Tween)
surfactants:interfacial and microstructural phenomena. RSC Advances, 2013,
3, 6945. DOI: 10.1039/c3ra22691c.
115. Rub MA, Khan JM, Yaseen Z, Khan RH and Kabir-ud-Din. Conformational
changes of serum albumin upon complexation with amphiphilic drug
23
impramine hydrochloride. Journal of Proteins and Proteomics, (2012) 3(3):
207-215.
116. Khan JM, Qadeer A, Ahmad E, Ashraf R, Bushan B,Chaturvedi S.K.,
Rabbani, G, Khan RH. Monomeric banana lectin at acidic ph overrules
conformational stability of its native dimeric form. PLoS One (2013) 8,
e62428
117. Zaidi N, Ajmal MR, Rabbani G, Ahmad E, Khan RH. (2013). A
comprehensive insight into binding of hippuric acid to human serum
albumin: A study to uncover its impaired elimination through
hemodialysis. PloS One 8, e71422.
118. Hassan MI, Naeem A, Khan KA, Khan RH, Singh S, Singh TP,Yadav S.
Protective effect of prolactin induced protein on zinc alhpa2-glycoprotein
against various denaturants. J Proteins Proteomics (2012) 3(2), 103-109.
119. Rub MA, Asiri AM, Khan JM, Khan RH, Kabir-ud-Din. Interaction of
gelatin with promethazine hydrochloride: conductimetry, tensiometry and
circular dichroism studies. J Mol Struc (2013) 35-42.
120. Iram A, Alam T, Khan J.M, Khan T.A, Khan R.H, and Naeem A. Molten
globule of hemoglobin proceeds into aggregates and advanced glycated end
products. PloS One ( 2013)e72075
121. Qadeer A, Ahmad E, Zaman M, Khan MW, Khan JM, Rabbani G, Tarique
KF, Sharma G, Gourinath S, Nadeem S, Badr G, Khan RH. (2013)
Concentration dependent antagonistic persuasion of sds and naphthalene
derivatives on the fibrillation of stem bromelain. Arch. Biochem. Biophys.
(2013)540:101-116.
122. Khan JM., Chaturvedi SK., Khan RH. Elucidating the mode of action of urea
on mammalian serum albumins and protective effect of sodium dodecyl
sulfate. Biochm Biophys Res Comm (2013) 441: 681-688.
123. Khan J M, Chaturvedi S K, Rehman S K, Ishtikhar M, Qadeer A, Ahmed E
and Khan R H. Protonation Favors aggregation of Lysozyme with SDS. Soft
Matter, 2014, 10, 2591.
124. Khan JM, Abdulrehman SA, Zaidi KF, Gourinath S, Khan RH.
Hydrophobicity alone cannot trigger aggregation in protonated mammalian
serum albumins. Phys Chem Chem Phys (2014)16, 5150-5161
24
125. Ansari NA, Moinuddin, Mir A R, Habib S, Alam K, Ali A, Khan RH. Role of
early glycation amadori products of lysine-rich proteins in the production of
autoantibodies in diabetes type 2 patients. Cell Biochem Biophys (2014)
9991-7
126. Varshney A, Rabbani G, Badr G, Khan RH. Cosolvents induced unfolding
and aggregation of keyhole limpet hemocyanin. Cell Biochem Biophys
(2014) 69, 103–113.
127. Rabbani G, Kaur J, Ahmad E, Khan RH, Jain SK. Structural characteristics of
thermostable immunogenic outer membrane protein from Salmonella
enterica serovar Typhi (S. Typhi). Appl Microbiol Biotechnol(2014)
98,2533-2543.
128. Khan MF, Hameedullah M, Ansari AH, Ahmad E, Lohani MB, Khan
RH, Alam MM, Khan W, Husain FM, Ahmad I. Flower-shaped ZnO
nanoparticulates synthesized by a novel approach at near-room temperatures
with antibacterial and antifungal properties. Int J Nanomed (2014). 9, 853-
864.
129. Afrin S, Riyazuddeen, Rabbani G, and Khan RH. Spectroscopic and
Calorimetric studies of interaction of methimazole with human serum
albumin. Journal of Luminescence 151 (2014) 219-223
130. Fatima S, Ajmal R, Badr G and Khan RH. Harmful effect of detergent on
lipase. Cell Biochem Biophysics DOI 10.1007/s12013-014-9978-4.
131. Qadeer A, Zaman M, Khan RH. Inhibitory effect of post-micellar SDS
conecentration on the thermal aggregation and activity of papain.
Biochemistry (Moscow)(2014) 79, 785-796.
132. Khan MV, Rabbani G, Ahmad E, Khan RH. Fluoroalcohols-induced
modulation and amyloid formation in conalbumin. Int J Biol Macromol.
(2014) 22, 606-614.
133. Malik Abdul Rub, Abdullah M. Asiri, Javed Masood Khan, Farah Khan,
Khan RH, Kabir-ud-Din. A study of interaction between antidepressant drug
nortriptyline hydrochloride with gelatin. Journal of the Taiwan Institute of
Chemical Engineers (2014).
134. Varshney A, Ansari Y, Zaidi N, Ahmad E, Badr G, Alam P, Khan RH.
Analysis of binding interaction between antibacterial ciprofloxacin and human
25
serum albumin by spectroscopic techniques. Cell Biochem Biophys (2014)
70, 93-101.
135. Rub MA, Asiri AM, Khan JM, Khan RH, Kabir-ud-Din. Study on the
interaction between amphiphilic drug and bovine serum albumin: A
thermodynamic and spectroscopic description. J Lumin (2014) 155, 39-46.
136. MA, Khan JM, Khan F, Khan RH, Din K, A study of interaction between
antidepressant drug nortriptyline hydrochloride with gelatin. Journal of
Taiwan Institute of Chemical Engineers.45, (5), 2068–2074
137. Amani S, Nasim F, Khan TA, Fazili NA, Furkan M, Bhat IA, Khan JM, Khan
RH, Naeem A. Detergent induces the formation of IgG aggregates: A multi-
methodological approach. Spectrochim Acta A Mol Biomol Spectrosc.
(2014) 120, 151-160.
138. Shakir M, Khan MS, Al-Resayes SI, Baig U, Alam P, Khan RH, Alam M. In-
vitro DNA binding, molecular docking and antimicrobial studies on newly
synthesized poly(o-toluidine)-titanium dioxide nanocomposite. RSC Adv
(2014).
139. Rabbani G, Khan MJ, Ahmad A, Yusof MM, Khan RH. Effect of copper
oxide nanoparticles on the conformation and activity of β-galactosidase.
Colloids Surf B Biointerfaces (2014).DOI: 10.1016/j.colsurfb.2014.08.035.
140. Ishtikhar M, Rabbani G, Khan RH. Interaction of 5-fluoro-5'-deoxyuridine
with human serum albumin under physiological and non-physiological
condition: a biophysical investigation. Colloids Surf B Biointerfaces. 2014
Nov 1; 123:469-77.
141. Ashraf JM, Ahmad S, Rabbani G, Jan AT, Lee EJ, Khan RH.
Physicochemical analysis of structural alteration and advanced glycation end
products generation during glycation of H2A histone by 3-deoxyglucosone.
IUBMB Life. 2014 Oct;66(10):686-93
142. Qadeer A, Zaman M, Khan RH. Inhibitory effect of post-micellar SDS
concentration on thermal aggregation and activity of papain. Biochemistry
(Mosc). 2014 Aug;79(8):785-96
143. Zaidi N, Nusrat S, Zaidi FK, Khan RH. pH-dependent differential interacting
mechanisms of sodium dodecyl sulfate with bovine serum fetuin: a
biophysical insight. J Phys Chem B. 2014 Nov 20;118(46):13025-36.
26
144. Ishtikhar M, Rabbani G, Khan S and Khan RH. Biophysical investigation
of Thymoquinone Binding to ‘N’ and ‘B’-isoform of Human serum albumin
and explore the Interaction Mechanism and Radical Scavenging Activity. RSC
Adv., 2014, Accepted Manuscript
145. Ishtikhar M, Khan S, Badr G, Osama Mohamed A, Khan RH. Interaction of
the 5-fluorouracil analog 5-fluoro-2'-deoxyuridine with 'N' and 'B' isoforms of
human serum albumin: a spectroscopic and calorimetric study.Mol
Biosyst. 2014 Nov;10(11):2954-64
146. Chaturvedi SK, Ahmad E, Khan JM, Alam P, Ishtikhar M, Khan RH.
Elucidating the interaction of limonene with bovine serum albumin: a multi-
technique approach. Mol Biosyst. 2015 Jan;11(1):307-16
147. Ahmad P, Islam BU, Allarakha S, Rabbani G, Dixit K, Moinuddin, Khan RH,
Siddiqui SA, Ali A.. Preferential recognition of peroxynitrite-modified human
serumalbumin by circulating autoantibodies in cancer. International Journal
of Biological Macromolecules 72 (2015) 875–882
148. Gull N, Khan JM, Ishtikhar M, Qadeer A, Khan RA, Gul M, Khan RH.
Secondary structural changes in guanidinium hydrochloride denatured
mammalian serum albumins and protective effect of small amounts of cationic
gemini surfactant pentanediyl-α,ω-bis(cetyldimethylammonium bromide) and
methyl-β-cyclodextrin: A spectroscopic study. J Colloid Interface Sci. 2015
Feb 1;439:170-6
149. Iram N, Khan MS, Jolly R, Arshad M, Alam M, Alam P, Khan RH, Firdaus
F. Interaction mode of Polycarbazole-titanium dioxide nanocomposite with
DNA: molecular docking simulation and In-vitro antimicrobial study. Journal
of Photochemistry and Photobiology B: Biology 2015.
150. Ahmad B, Muteeb G, Alam P, Varshney A, Zaidi N, Ishtikhar M, Badr G,
Mahmoud MH, Khan RH Thermal induced unfolding of human serum
albumin isomers: Assigning residual α-helices to domain II. International
journal of biological macromolecules 2015 75:447-52.
151. Ishtikhar M, Usmani SS, Gull N, Badr G, Mahmoud MH, Khan RH.
Inhibitory effect of copper nanoparticles on rosin modified surfactant induced
aggregation of lysozyme. International journal of biological
macromolecules 2015 78:379-88.
27
152. Ishtikhar M, Rabbani G, Khan S, Khan RH. Biophysical investigation of
thymoquinone binding to ‘N’and ‘B’ isoforms of human serum albumin:
exploring the interaction mechanism and radical scavenging activity. RSC
Advances 2015 5:18218-32.
153. Chaturvedi SK, Alam P, Khan JM, Siddiqui MK, Kalaiarasan P, Subbarao N,
Ahmad, Z, Khan RH,. Biophysical insight into the anti-amyloidogenic
behavior of taurine. International journal of biological macromolecules
2015;80:375-84
154. Khan MV, Rabbani G, Ishtikhar M, Khan S, Saini G, Khan RH. Non-
fluorinated cosolvents: A potent amorphous aggregate inducer of
metalloproteinase-conalbumin (ovotransferrin). International journal of
biological macromolecules2015 78:417-28.
155. Allarakha S, Ahmad, Ishtikhar M, Zaheer MS, Siddiqi SS, and Ali MA.
Fructosylation generates neo-epitopes on human serum albumin. 2015.
DOI: 10.1002/iub.1375
156. Alam P, Naseem F, Abdelhameed AS, Khan RH. Effect of galactose on acid
induced molten globule state of Soybean Agglutinin: Biophysical approach.
Journal of Molecular Structure 2015;1099:149-53.
157. Alam P, Rabbani G, Badr G, Badr BM, Khan RH. The Surfactant-Induced
Conformational and Activity Alterations in Rhizopus niveus Lipase. Cell
biochemistry and biophysics 2015;71:1199-206.
158. Alam P, Chaturvedi SK, Anwar T, Siddiqi MK, Ajmal MR, Badr
G,Mahmoud MH, Khan RH. Biophysical and molecular docking insight into
the interaction of cytosine b-D arabinofuranoside with human serum albumin.
Journal of Luminescence 2015;164:123-30.
159. Ishtikhar M, Khan A, Chang C-K, Lin LT-W, Wang SSS, Khan RH. Effect
of Guanidine hydrochloride and Urea on the interaction of 6-thioguanine with
human serum albumin: A spectroscopic and molecular dynamics based study.
Journal of Biomolecular Structure and Dynamics 2015:1-38.
160. Ishtikhar M, Ali MS, Atta AM, Al-Lohedan HA, Nigam L, Subbarao N,
Khan RH. Interaction of biocompatible natural rosin-based surfactants with
human serum albumin: A biophysical study. Journal of Luminescence
2015;167:399-407.
28
161. Rout KC, Chaturvedi SK, Khan RH, Mondal B. A copper (II) complex as
selective turn-on fluorosensor for nitric oxide and its intracellular application.
Inorganica Chimica Acta 2015;437:201-6.
162. Sohail A, Bhat SA, Siddiqui AA, Zaman M, Khan RH, Bano B.
Conformational transitions induced by in vitro macromolecular crowding lead
to the amyloidogenesis of buffalo heart cystatin. Journal of Molecular
Recognition 2015.
163. Ashraf JM, Rabbani G, Ahmad S, Hasan Q, Khan RH, Alam K, et al.
Glycation of H1 Histone by 3-Deoxyglucosone: Effects on Protein Structure
and Generation of Different Advanced Glycation End Products. PloS one
2015;10.
164. Rabbani G, Ahmad E, Khan MV, Ashraf MT, Bhat R, Khan RH. Impact of
structural stability of cold adapted Candida antarctica lipase B (CaLB): in
relation to pH, chemical and thermal denaturation. RSC Advances
2015;5:20115-31.
165. Ashraf J1, Ahmad S, Rabbani G, Hasan Q, Jan AT, Lee EJ, Khan RH, Alam
K, Choi I. 3-Deoxyglucosone: a potential glycating agent accountable for
structural alteration in H3 histone protein through generation of different
AGEs. PloS One 2015. DOI:10.1371/journal.pone.0116804
166. Ishtikhar M, Khan MV, Khan S, Chaturvedi SK, Badr G, Mahmoud MH and
Khan RH. Biophysical and molecular docking insight into interaction
mechanism and thermal stability of human serum albumin isoforms with a
semi-synthetic water-soluble camptothecin analog irinotecan hydrochloride.
2015. Journal of Biomolecular Structure and Dynamics.
167. Chaturvedi SK, Zaidi N, Alam P, Khan JM, Qadeer A, Siddique IA, Asmat S,
Zaidi Y and Khan RH. Unraveling Comparative Anti-Amyloidogenic
Behavior of Pyrazinamide and D-Cycloserine: A Mechanistic Biophysical
Insight.PLoS One (2015). DOI:10.1371/journal.pone.0136528
168. Ishtikhar M, Chandel TI, Ahmad A, Ali MS, Al-Lohadan HA, Atta AM,
Khan RH. Rosin Surfactant QRMAE Can Be Utilized as an Amorphous
Aggregate Inducer: A Case Study of Mammalian Serum Albumin. PLoS One
(2015). DOI: 10.1371/journal.pone.0139027.
29
169. Kumar S, Khan RH and Khare SK. Structural Elucidation and Molecular
Characterization of Marinobacter Sp. α -Amylase. Prep Biochem Biotechnol.
2015
170. Abdelhameed AS, Alam P and Khan RH. Binding of Janus Kinase Inhibitor
Tofacitinib with Human serum Albumin: Multi-technique approach doi:
10.1371/journal.pone.0139027. Journal of Biomolecular Structure and
Dynamics.2015
171. Ishtikhar M, Ali MS, Atta AM, Al-Lohedan H, Badr G, Khan RH.
Temperature dependent rapid annealing effect induces amorphous aggregation
of human serum albumin. International journal of biological
macromolecules2015
172. Thakur K, Kaur M, Rabbani G, Khan RH, Sukhdev Singh, Jatinder Singh
Structural variations and molten globule state in Arisaema helliborifolium
lectin under various treatments as monitored by spectroscopy. Protein
Peptide Letters 2015 (Accepted manuscript)
173. Ishtikhar M, Ali MS, Atta AM, Al-Lohedan HA, Nigam L, Subbarao N,
Khan RH. Interaction of biocompatible natural rosin-based surfactants with
human serum albumin: A biophysical study. Journal of Luminescence 2015
174. Sohail A, Bhat SA, Siddiqui AA, Zaman M, Khan RH, Bano B.
Conformational transitions induced by in vitro macromolecular crowding lead
to the amyloidogenesis of buffalo heart cystatin. Journal of Molecular
Recognition 2015
175. Chaturvedi, Sumit Kumar, Parvez Alam, Javed Masood Khan, Mohd
Khursheed Siddiqui, Ponnusamy Kalaiarasan, Naidu Subbarao, Zeeshan
Ahmad, and Rizwan Hasan Khan. "Biophysical insight into the anti-
amyloidogenic behavior of taurine." International journal of biological
macromolecules 80 (2015): 375-384.
176. MR, Zaidi N, Alam P, Nusrat S, Siddiqi MK, Badr G, Mahmoud MH, Khan
RH. Insight into the Interaction of antitubercular and anticancer compound
Clofazimine with Human Serum Albumin: spectroscopy and molecular
modeling. Journal of Biomolecular Structure and Dynamics 2015
177. Iram N, Khan MS, Jolly R, Arshad M, Alam M, Alam P, Khan RH, Farha
Firdaus. Interaction mode of polycarbazole–titanium dioxide nanocomposite
30
with DNA: Molecular docking simulation and in-vitro antimicrobial study.
Journal of Photochemistry and Photobiology B: Biology 2015
178. Thakur K, Kaur M, Rabbani G, Khan RH, S Singh, J Singh. Biophysical
Characterization of the Nucleoside Diphosphate Kinase of Leishmania major
and Effect of the P95S Mutation. Protein & Peptide Letters 2016
179. Khan JM, Khan MS, Ali MS, Al-Shabib NA, Khan RH.
Cetyltrimethylammonium bromide (CTAB) promote amyloid fibril formation
in carbohydrate binding protein (concanavalin A) at physiological pH. RSC
Advances 2016
180. Zaman M, Chaturvedi SK, Zaidi N, Qadeer A, Chandel TI, Nusrat S, Alam P,
Khan RH. DNA induced aggregation of stem bromelain; a mechanistic
insight. RSC Advances 2016
181. Hoque M, Gupta J, Rabbani G, Khan RH, M Saleemuddin. Behaviour of
oleic acid-depleted bovine alpha-lactalbumin made LEthal to tumor cells
(BAMLET). Molecular BioSystems 2016
182. Chaturvedi SK, Khan JM, Siddiqi MK, Alam P, Khan RH. Comparative
insight into surfactants mediated amyloidogenesis of lysozyme. International
journal of biological macromolecules 2016
183. Ajmal MR, Abdelhameed AS, Alam P, Khan RH. Interaction of new kinase
inhibitors cabozantinib and tofacitinib with human serum alpha-1 acid
glycoprotein. A comprehensive spectroscopic and molecular Docking
approach. Spectrochimica Acta Part A: Molecular and Biomolecular
Spectroscopy 2016
184. Alam P, Abdelhameed AS, Rajpoot RK, Khan RHInterplay of multiple
interaction forces: Binding of tyrosine kinase inhibitor nintedanib with human
serum albumin. Journal of Photochemistry and Photobiology B: Biology
2016
185. Zaman M, Zakariya SM, Nusrat S, Khan MV, Qadeer A, Ajmal MR, Khan
RH. Surfactant-mediated amyloidogenesis behavior of stem bromelain; A
biophysical insight. Journal of Biomolecular Structure and Dynamics 2016
186. Abdelhameed AS, Ajmal MR, Ponnusamy K, Subbarao N, Khan RH.
Interaction of the recently approved anticancer drug nintedanib with human
31
acute phase reactant α 1-acid glycoprotein. Journal of Molecular Structure
2016
187. Naeem A, Bhat SA, Iram A, Khan RH. Aggregation of intrinsically
disordered fibrinogen as the influence of backbone conformation. Archives of
biochemistry and biophysics 2016
188. Ajmal MR, Nusrat S, Alam P, Zaidi N, Badr G, Mahmoud MH, Rajpoot RK,
Khan RH. Differential mode of interaction of ThioflavinT with native β
structural motif in human α 1-acid glycoprotein and cross beta sheet of its
amyloid: Biophysical and molecular docking approach. Journal of Molecular
Structure 2016
189. Siddiqi MK, Shahein YE, Hussein N, Khan RH. Effect of surfactants on Ra-
sHSPI–A small heat shock protein from the cattle tick Rhipicephalus
annulatus. Journal of Molecular Structure 2016.
190. Alam P, Chaturvedi SK, Siddiqi MK, Rajpoot RK, Ajmal MR, Zaman
M, Khan RH Vitamin k3 inhibits protein aggregation: Implication in the
treatment of amyloid diseases. Sci Rep. 2016 May 27;6:26759. doi:
10.1038/srep26759
191. RH Khan, MK Siddiqui, P Salahuddin (2016) Protein Disulfide Isomerase:
Structure, Mechanism of Oxidative Protein Folding and Multiple Functional
Roles. Journal of Biochemistry and Molecular Biology Research 2 (3),
173-179.
192. Ajmal MR, Chaturvedi SK, Zaidi N, Alam P, Zaman M, Siddiqi MK, Nusrat
S, Jamal MS, Mahmoud MH, Badr G, Khan RH. (2016) Biophysical insights
into the interaction of hen egg white lysozyme with therapeutic dye
clofazimine: modulation of activity and SDS induced aggregation of model
protein. J Biomol Struct Dyn. 2016 Aug 5:1-14
193. M Furkan, A Rizvi, M Afsar, M Rehan Ajmal, RH Khan, A Naeem (2016)
In Vitro Elucidation of the Folding Intermediates and Aggregate Formation of
Hemoglobin Induced by Acetonitrile: A Multispectroscopic Approach Protein
and Peptide Letters 23 (10), 884-891
194. S Iram, S Khan, AA Ansary, M Arshad, S Siddiqui, E Ahmad, RH Khan
(2016) Biogenic terbium oxide nanoparticles as the vanguard against
32
osteosarcoma Spectrochimica Acta Part A: Molecular and Biomolecular
Spectroscopy 168, 123-131.
195. MK Siddiqi, P Alam, SK Chaturvedi, RH Khan (2016) Anti-amyloidogenic
behavior and interaction of Diallylsulfide with Human Serum Albumin
International Journal of Biological Macromolecules 92, 1220-1228.
196. S Nusrat, N Zaidi, M Zaman, S Islam, MR Ajmal, MK Siddiqi, MK Santra,
RH Khan (2016) Repositioning nordihydroguaiaretic acid as a potent
inhibitor of systemic amyloidosis and associated cellular toxicity Archives of
Biochemistry and Biophysics 612, 78-90.
197. Nusrat S, Siddiqi MK, Zaman M, Zaidi N, Ajmal MR, Alam P, Qadeer A,
Abdelhameed AS, Khan RH. (2016) A Comprehensive Spectroscopic and
Computational Investigation to Probe the Interaction of Antineoplastic Drug
Nordihydroguaiaretic Acid with Serum Albumins. PLoS One. 2016 Oct
13;11(10):e0164927.
198. Laskar K, Alam P, Khan RH, Rauf A. Synthesis, characterization and
interaction studies of 1,3,4-oxadiazole derivatives of fatty acid with human
serum albumin (HSA): A combined multi-spectroscopic and molecular
docking study Eur J Med Chem. 2016 Oct 21;122:72-8.
199. M Ishtikhar, MV Khan, RH Khan (2016) Anti-aggregation property of
thymoquinone induced by copper-nanoparticles: A biophysical approach.
International Journal of Biological Macromolecules 93, 1174-1182.
200. SK chaturvedi, MK Siddiqi, P Alam, M Zaman, RH Khan. Comparative
binding study of anti-tuberculosis drug pyrazinamide with serum albumins.
RSC Advances. 2016,6, 85860-85869.
201. Laskar, Khairujjaman, Parvez Alam, Rizwan Hasan Khan, and Abdul Rauf.
"Synthesis, characterization and interaction studies of 1, 3, 4-oxadiazole
derivatives of fatty acid with human serum albumin (HSA): A combined
multi-spectroscopic and molecular docking study." European journal of
medicinal chemistry 122 (2016): 72-78.
202. Zaman, Masihuz, Aquib Ehtram, Sumit Kumar Chaturvedi, Saima Nusrat,
and Rizwan Hasan Khan. "Amyloidogenic behavior of different intermediate
state of stem bromelain: A biophysical insight." International journal of
biological macromolecules 91 (2016): 477-485.
33
203. Ajmal, Mohammad Rehan, Nida Zaidi, Parvez Alam, Saima Nusrat, Mohd
Khursheed Siddiqi, Gamal Badr, Mohamed H. Mahmoud, and Rizwan Hasan
Khan. "Insight into the Interaction of antitubercular and anticancer compound
Clofazimine with Human Serum Albumin: spectroscopy and molecular
modelling." Journal of Biomolecular Structure and Dynamics 35, no. 1
(2017): 46-57.
204. Ajmal, Mohammad Rehan, Tajalli Ilm Chandel, Parvez Alam, Nida Zaidi,
Masihuz Zaman, Saima Nusrat, Mohsin Vahid Khan Rizwan Hasan Khan.
"Fibrillogenesis of human serum albumin in the presence of levodopa–
spectroscopic, calorimetric and microscopic studies." International journal
of biological macromolecules 94 (2017): 301-308.
205. Nasir, Zeba, Mohammad Shakir, Rizwan Wahab, Mohd Shoeb, Parvez Alam,
Rizwan Hasan Khan, and Mohammad Mobin. "Co-precipitation synthesis
and characterization of Co doped SnO2 NPs, HSA interaction via various
spectroscopic techniques and their antimicrobial and photocatalytic
activities." International journal of biological macromolecules 94 (2017):
554-565.
206. Z Nasir, M Shakir, R Wahab, M Shoeb, P Alam, RH Khan, M Mobin (2017)
Co-precipitation synthesis and characterization of Co doped SnO 2 NPs, HSA
interaction via various spectroscopic techniques and their antimicrobial and
photocatalytic activities International Journal of Biological
Macromolecules 94, 554-565
207. MV Khan, M Ishtikhar, G Rabbani, M Zaman, AS Abdelhameed, RH Khan
(2017) Polyols (Glycerol and Ethylene glycol) mediated amorphous aggregate
inhibition and secondary structure restoration of metalloproteinase-
conalbumin (ovotransferrin). International Journal of Biological
Macromolecules 94, 290-300.
208. MR Ajmal, TI Chandel, P Alam, N Zaidi, M Zaman, S Nusrat, MV Khan,
Siddiqi MK, Shahein YE, Mahmoud MH, Badr G, RH Khan.(2017)
Fibrillogenesis of human serum albumin in the presence of levodopa–
spectroscopic, calorimetric and microscopic studies. International Journal of
Biological Macromolecules 94, 301-308.
34
209. Mohd Rehan Ajmal, Nusrat S, Alam P, Zaidi N, Khan MV, Masihuz Zaman,
Yasser E. Shahein, Mohd H Mahmoud, Badr G, Khan RH, Interaction of
anticancer drug clofarabine with human serum albumin and human α-1 acid
glycoprotein. Spectroscoic and molecular docking approach. Journal of
Pharmaceutical and Biomedical Analysis, 135, 106-115.
210. Gupta J, Hoque M, Zaman M, Khan RH, Saleemuddin M.(2016) A
detergent-based procedure for the preparation of IgG-like bispecific antibodies
in high yield. Sci Rep. 2016 Dec 16;6:39198. doi: 10.1038/srep39198.
211. Nusrat S, Zaidi N, Siddiqi MK, Zaman M, Siddique IA, Ajmal MR,
Abdelhameed AS, Khan RH Anti-Parkinsonian L-Dopa can also act as anti-
systemic amyloidosis—A mechanistic exploration International Journal of
Biological Macromolecules 99, 630-640
212. Alam P, Siddiqi MK, Chaturvedi SK, Zaman M, Khan RH. Vitamin B12
offers neuronal cell protection by inhibiting Aβ-42 amyloid fibrillation
International Journal of Biological Macromolecules 99, 477-482
213. Khan MV, Ishtikhar M, Siddiqui MK, Zaman M, Chandel TI, Majid N,
Ajmal MR, Abdelhameed AS, Shahein YE, Khan RH Biophysical insight
reveals Tannic acid as amyloid inducer and conformation transformer from
amorphous to amyloid aggregates in Concanavalin A (ConA) Journal of
Biomolecular Structure and Dynamics, 1-41
214. Khan JM, Khan MS, Qadeer A, Alsenaidy MA, Ahmad A, Al-Shabib NA,
Khan RH Cationic Gemini Surfactant (16-4-16) interact electrostatically with
anionic plant lectin and facilitates amyloid fibril formation at neutral pH
Colloids and Surfaces A: Physicochemical and Engineering Aspects 522,
494–502
215. Alam MM, Qais FA, Ahmad I, Alam P, Khan RH, Naseem I Multi-
spectroscopic and molecular modelling approach to investigate the interaction
of riboflavin with human serum albumin Journal of Biomolecular Structure
and Dynamics, 1-15
216. Akram M, Ansari F, Bhat IA, Chaturvedi SK, Khan RH An ester-
functionalized cationic gemini surfactant mediated structural transitions of
porcine serum albumin (PSA) via binding interaction Colloids and Surfaces
A: Physicochemical and Engineering Aspects 516, 245-253
35
217. Siddiqi MK, Alam P, Chaturvedi SK, Nusrat S, Shahein YE, Khan RH
Attenuation of amyloid fibrillation in presence of Warfarin: A biophysical
investigation International Journal of Biological Macromolecules 95, 713-
718
218. Zaman M, Nusrat S, Zakariya SM, Khan MV,Ajmal MR, Khan RH
Elucidating the interaction of clofazimine with bovine liver catalase; a
comprehensive spectroscopic and molecular docking approach Journal of
Molecular Recognition DOI: 10.1002/jmr.2619
219. Rabbani, Gulam, Mohammad Hassan Baig, Arif Tasleem Jan, Eun Ju Lee,
Mohsin Vahid Khan, Masihuz Zaman, Abd-ElAziem Farouk, Rizwan Hasan
Khan, and Inho Choi. "Binding of erucic acid with human serum albumin
using a spectroscopic and molecular docking study." International journal of
biological macromolecules 105 (2017): 1572-1580.
220. Alam P, Beg AZ, Siddiqi MK, Chaturvedi SK, Rajpoot RK, Ajmal MR,
Zaman M, Abdelhameed AS, Khan RH Ascorbic acid inhibits human insulin
aggregation and protects against amyloid induced cytotoxicity Archives of
Biochemistry and Biophysics (accepted)
221. Furkan M, Rizvi A, Alam MT, Zaman M, Khan RH, Naeem A Serotonin
abrogates dopamine induced aggregation of cytochrome c International
Journal of Biological Macromolecules (accepted)
222. Gull, N., Ishtikhar, M., Alam, M. S., Andrabi, S. N. S., & Khan, R. H.
(2017). Spectroscopic studies on the comparative refolding of guanidinium
hydrochloride denatured hen egg-white lysozyme and Rhizopus niveus lipase
assisted by cationic single-chain/gemini surfactants via artificial chaperone
protocol. RSC Advances, 7(45), 28452-28460.
223. Khan, Javed Masood, Mohd Shahnawaz Khan, Mohammad Abdulrahman
Alsenaidy, Anwar Ahmed, Priyankar Sen, Mohammad Oves, Nasser
Abdulatif Al-Shabib, and Rizwan Hasan Khan. "Sodium louroyl sarcosinate
(sarkosyl) modulate amyloid fibril formation in hen egg white lysozyme
(HEWL) at alkaline pH: a molecular insight study." Journal of Biomolecular
Structure and Dynamics (2017): 1-16.
224. Abdelhameed, Ali Saber, Saima Nusrat, Mohammad Rehan Ajmal, Syed
Mohammad Zakariya, Masihuz Zaman, and Rizwan Hasan Khan. "A
36
biophysical and computational study unraveling the molecular interaction
mechanism of a new Janus kinase inhibitor Tofacitinib with bovine serum
albumin." Journal of Molecular Recognition 30, no. 6 (2017).
225. Alam, Parvez, Mohammad Khursheed Siddiqi, Sumit Kumar Chaturvedi,
Masihuz Zaman, and Rizwan Hasan Khan. "Vitamin B12 offers neuronal
cell protection by inhibiting Aβ-42 amyloid fibrillation." International
journal of biological macromolecules 99 (2017): 477-482.
226. Ishtikhar, M., M. S. Ali, R. H. Khan, and N. Kishore. "Anti-aggregation
effect of thymoquinone and copper nano-particles: A biophysical insight."
In EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS
LETTERS, vol. 46, pp. S162-S162. 233 SPRING ST, NEW YORK, NY
10013 USA: SPRINGER, 2017.
227. Ali, Abad, Mohd Asif, Parvez Alam, Mohammad Jane Alam, Mohd Asif
Sherwani, Rizwan Hasan Khan, and Shabbir Ahmad. "DFT/B3LYP
calculations, in vitro cytotoxicity and antioxidant activities of steroidal
pyrimidines and their interaction with HSA using molecular docking and
multispectroscopic techniques." Bioorganic chemistry 73 (2017): 83-99.
228. Abdelhameed, Ali Saber, Saima Nusrat, Sanjhi Paliwal, Masihuz Zaman,
Nida Zaidi, and Rizwan Hasan Khan. "A multitechnique approach to probe
the interaction of a therapeutic tyrosine kinase inhibitor nintedanib and bovine
serum albumin." Preparative Biochemistry and Biotechnology 47, no. 7
(2017): 655-663.
229. Khan, Mohsin Vahid, Masihuz Zaman, Tajalli Ilm Chandel, Mohammad
Khursheed Siddiqui, Mohd Rehan Ajmal, Ali Saber Abdelhameed, and
Rizwan Hasan Khan. "Cationic surfactant mediated fibrillogenesis in bovine
liver catalase: A biophysical approach." Journal of Biomolecular Structure
and Dynamics (2017): 1-15.
230. Gull, Nuzhat, Javed Masood Khan, and Rizwan Hassan Khan.
"Spectroscopic studies on the gemini surfactant mediated refolding of human
serum albumin." International journal of biological macromolecules 102
(2017): 331-335.
231. Chandel, Tajalli Ilm, Masihuz Zaman, Mohsin Vahid Khan, Maroof Ali,
Gulam Rabbani, Mohd Ishtikhar, and Rizwan Hasan Khan. "A mechanistic
37
insight into protein-ligand interaction, folding, misfolding, aggregation and
inhibition of protein aggregates: An overview." International journal of
biological macromolecules (2017).
232. Khan, Javed Masood, Mohammad A. Alsenaidy, Mohd Shahnawaz Khan,
Priyankar Sen, Rizwan Hasan Khan, and Sadaf Fatima. "pH induced single
step shift of hydrophobic patches followed by formation of an MG state and
an amyloidogenic intermediate in Lima Bean Trypsin Inhibitor
(LBTI)." International journal of biological macromolecules 103 (2017):
111-119.
233. Zaidi, Nida, and Rizwan Hasan Khan. "Mechanistic insight into interaction
of Sodium Dodecyl Sulphate to asialylated form of glycoprotein: A mimic of
membrane protein-lipid system." International journal of biological
macromolecules 103 (2017): 65-73.
234. Ansari, Sameer Shakeel, Rizwan Hasan Khan, and Saeeda Naqvi. "Probing
the intermolecular interactions into serum albumin and anthraquinone
systems: a spectroscopic and docking approach." Journal of Biomolecular
Structure and Dynamics (2017): 1-14.
235. Rehman, Ahmed Abdur, Masihuz Zaman, Mohammad Khalid Zia, Haseeb
Ahsan, Rizwan Hasan Khan, and Fahim Halim Khan. "Conformational
behavior of alpha-2-macroglobulin: Aggregation and inhibition induced by
TFE." International journal of biological macromolecules 104 (2017): 539-
546.
236. Kumari, Neha, Sumit Kumar Chaturvedi, Rehan Khan, Alpana Sharma,
Rizwan Hasan Khan, and Savita Yadav. "Characterization of CNL like
protein fragment (CNL-LPF) from mature Lageneria siceraria
seeds." International journal of biological macromolecules 104 (2017):
1194-1203.
237. Thakur, Kshema, Tarnjeet Kaur, Jatinder Singh, Gulam Rabbani, Rizwan H.
Khan, Rachna Hora, and Manpreet Kaur. "Sauromatum guttatum lectin:
Spectral studies, lectin-carbohydrate interaction, molecular cloning and in
silico analysis." International journal of biological macromolecules104
(2017): 1267-1279.
38
238. Nusrat, Saima, and Rizwan Hasan Khan. "Exploration of ligand induced
protein conformational alteration, aggregate formation and its inhibition: A
biophysical insight." Preparative Biochemistry and Biotechnology (2017).
239. Siddiqi, Mohammad Khursheed, Parvez Alam, Sumit Kumar Chaturvedi,
Saima Nusrat, Mohammad Rehan Ajmal, Ali Saber Abdelhameed, and
Rizwan Hasan Khan. "Probing the interaction of cephalosporin antibiotic–
ceftazidime with human serum albumin: A biophysical
investigation." International journal of biological macromolecules 105
(2017): 292-299.
240. Zaman, Masihuz, Syed Mohammad Zakariya, Saima Nusrat, Tajalli Ilm
Chandel, Syed Musthapa Meeran, Mohammad Rehan Ajmal, Parvez Alam,
and Rizwan Hasan Khan. "Cysteine as a potential anti-amyloidogenic agent
with protective ability against amyloid induced cytotoxicity." International
journal of biological macromolecules 105 (2017): 556-565.
241. Akram, Mohd, Farah Ansari, Imtiyaz Ahmad Bhat, Sumit Kumar Chaturvedi,
and Rizwan Hasan Khan. "Analyzing the interaction between porcine serum
albumin (PSA) and ester-functionalized cationic gemini surfactants." Process
Biochemistry 63 (2017): 145-153.
242. Nusrat, Saima, and Rizwan Hasan Khan. "Unraveling the Promising Action
of Promethazine against Amyloid Fibrillation of Human Lysozyme:
Implication towards Systemic Amyloidosis." In PROTEIN SCIENCE, vol.
26, pp. 14-14. 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY,
2017.
243. Zaman, Masihuz, Mohsin Vahid Khan, Syed Mohammad Zakariya, Saima
Nusrat, Syed Mustapha Meeran, Parvez Alam, Mohhamd Rehan Ajmal,
Yasser E. Shahein, Amira M. Abouelella, and Rizwan Hasan Khan. "Amino
group of salicylic acid exhibits enhanced inhibitory potential against insulin
amyloid fibrillation with protective aptitude towards amyloid induced
cytotoxicity." Journal of cellular biochemistry (2017).
244. Tantry, Irfan Qadir, Sana Waris, Safia Habib, Rizwan Hasan Khan, Riaz
Mahmood, and Asif Ali. "Hypochlorous acid induced structural and
conformational modifications in human DNA: A multi-spectroscopic
39
study." International journal of biological macromolecules 106 (2018):
551-558.
245. Nusrat, Saima, Masihuz Zaman, Aiman Masroor, Mohammad Khursheed
Siddqi, Nida Zaidi, Km Neelofar, Ali Saber Abdelhameed, and Rizwan
Hasan Khan. "Deciphering the enhanced inhibitory, disaggregating and
cytoprotective potential of promethazine towards amyloid
fibrillation." International journal of biological macromolecules 106
(2018): 851-863.
246. Chandel, Tajalli Ilm, Gulam Rabbani, MohsinVahid Khan, Masihuz Zaman,
Parvez Alam, Yasser E. Shahein, and Rizwan Hasan Khan. "Binding of anti-
cardiovascular drug to serum albumin: an insight in the light of spectroscopic
and computational approaches." Journal of Biomolecular Structure and
Dynamics 36, no. 1 (2018): 54-67.
247. Khan, Farzana, Abdul Rouf Mir, Sidra Islam, Minhal Abidi, Mohammed
Amir Husain, and Rizwan Hasan Khan. "Unsaturated aldehyde, 4-
hydroxynonenal (HNE) alters the structural integrity of HSA with
consequences in the immuno-pathology of rheumatoid
arthritis." International Journal of Biological Macromolecules (2018).
248. Siddiqi, Mohammad, Saima Nusrat, Parvez Alam, Sadia Malik, Sumit Kumar
Chaturvedi, Mohammad Rehan Ajmal, Ali Saber Abdelhameed, and Rizwan
Hasan Khan. "Investigating the site selective binding of busulfan to human
serum albumin: Biophysical and molecular docking
approaches." International journal of biological macromolecules 107
(2018): 1414-1421.
249. Al-Shabib, Nasser Abdulatif, Javed Masood Khan, Ajamaluddin Malik,
Abdulrahman M. Alsenaidy, Mohammad A. Alsenaidy, Fohad Mabood
Husain, Monis Bilal Shamsi, Syed Hidayathulla, and Rizwan Hasan Khan.
"Negatively charged food additive dye “Allura Red” rapidly induces SDS-
soluble amyloid fibril in beta-lactoglobulin protein." International journal of
biological macromolecules 107 (2018): 1706-1716.
250. Ishtikhar, Mohd, Ejaz Ahmad, Zeba Siddiqui, Shafeeque Ahmad, Mohsin
Vahid Khan, Masihuz Zaman, Saima Nusrat, Tajalli Ilm Chandel, Mohammad
Rehan Ajmal, and Rizwan Hasan Khan. "Biophysical insight into the
40
interaction mechanism of plant derived polyphenolic compound tannic acid
with homologous mammalian serum albumins." International journal of
biological macromolecules 107 (2018): 2450-2464.
251. Al-Shabib, Nasser Abdulatif, Javed Masood Khan, Mohammad A.
Alsenaidy, Abdulrahman M. Alsenaidy, Mohd Shahnawaz Khan, Fohad
Mabood Husain, Mohammad Rashid Khan Rizwan Hasan Khan. "Unveiling
the stimulatory effects of tartrazine on human and bovine serum albumin
fibrillogenesis: Spectroscopic and microscopic study." Spectrochimica Acta
Part A: Molecular and Biomolecular Spectroscopy 191 (2018): 116-124.
252. Khan, Mohsin Vahid, Syed Mohammad Zakariya, and Rizwan Hasan Khan.
"Protein folding, misfolding and aggregation: A tale of constructive to
destructive assembly." International journal of biological
macromolecules 112 (2018): 217-229.
253. Ajmal, Mohammad Rehan, Saima Nusrat, Parvez Alam, Nida Zaidi, Mohsin
Vahid Khan, Masihuz Zaman, Yasser E. Shahein, Mohamed H. Mahmoud,
Gamal Badr, and Rizwan Hasan Khan. "Interaction of anticancer drug
clofarabine with human serum albumin and human α-1 acid glycoprotein.
Spectroscopic and molecular docking approach." Journal of pharmaceutical
and biomedical analysis 135 (2017): 106-115.
REVIEW ARTICLES
1. Khan, R.H. and Khan, F. Models for protein folding and nature’s choice of
protein as a catalyst (2002) Biochemistry (Mosc.) 67(5), 520-524.
2. Khan, F., Khan, R.H. Sherwani, A.F., Mohmood, S. and Azfer, M.A. Lectins
as Markers for blood grouping. (2002)Med. Sci. Monit. 8 (12), 293-300.
3. Sherwani, A.F., Mohmood, S., Khan, F., Khan, R.H. and Azfer, M.A.
Characterization of lectins and their specificity in carcinoma-An appraisal.
(2003) Ind J Clin Biochem18 (2), 169-180.
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4. Mohmood, S., Sherwani, A., Khan, F., Khan, R.H. and Azfer, A. DNA
trinucleotide repeats expansion in neuropsychiatric patients. (2003) Med. Sci.
Monit. 9 (9) 237-245.
5. Ashraf, M.T. and Khan, R.H. Mitogenic Lectins (2003)Med. Sci. Monit. 9
(11), 265-269.
6. Haq, S.K., Atif, S.M. and Khan, R.H. Protein proteinase inhibitor genes in
combat against insects, pests and pathogens: natural and engineered
phytoprotection. . (2004) Arch. Biochem. Biophys. 431(1), 145-159.
7. Nayeem, M.S.and. Khan, R.H. Misfolded proteins and human diseases.
(2004) Protein Pept. Lett.11(6), 593-600.
8. Zahir, F., Rizwi, S.J., Haq, S.K. and Khan, R.H. Low dose mercury toxicity
and human health. (2005) Environ. Toxicol. Pharmacol. 20 (2), 351-360.
9. Ahmad, B. and Khan, R.H. Protein Folding: From hypothesis Driven to Data
mining. (2005) Pak. J. Biol. Sc. 8 (3), 487-492.
10. Nayeem, M.S. and Khan, R.H. Recombinant antibodies in cancer therapy.
(2006) Curr. Protein Pept. Sci. 7 (2), 165-170.
11. Naeem A., Saleemuddin M., and Khan, R.H. Glycoprotein targeting and
other applications of lectins in biotechnology.(2007)Curr. Prot. Pep. Sci. 8
(3), 261-273.
12. Varshney, A., Sen, P., Ahmad, E. and Khan, R.H. Ligand binding strategies
of human serum albumin:How can the cargo be utilized?(2010)
Chirality22(1), 77-87.
13. Haq, S.K., Rabbani, G.,Ahmad, E., Atif, S.M. and Khan, R.H. Protease
inhibitors: A Panacea J Biochem. Mol.Toxicol.(2010) 24(4):270-277.
14. Ahmad E., Ahmad A., Singh S., Arshad M., Khan A.H., Khan R.H., A
mechanistic approach for islet amyloid polypeptide aggregation to develop
antiamyloidogenic agents for type-2 diabetes. Biochimie. (2011) 93:793-805.
15. Ahmad A, Ahmad E, Rabbani G, Haque S, Arshad M, Khan RH.
Identification and design of antimicrobial peptides for therapeutic
applications. Curr Protein Pept Sci. (2012) 13:211-23
16. Ahmad E, Rabbani G, Zaidi N, Khan M A, Qadeer A, Ishtikhar M, Singh S,
Khan RH. Revisiting ligand induced conformational changes in protein:
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Essence Advancements Implication and Future challanges. JBiomol Stuc
Dyna (2012)31, 630-648.
17. Zaman M, Ahmad E, Qadeer A, Rabbani G, Khan RH. (2014). Nanoparticle
in relation to protein and peptide aggregation. IntJ Nanomedicine9, 899–912.
18. Salahuddin P, Rabbani G, Khan RH.The role of advanced glycation end
products in various types of neurodegenerative disease: a therapeutic
approach.Cell Mol Biol Lett(2014). DOI: 10.2478/s11658-014-0205-5,
19. Zahir F, Rabbani G, Khan RH, Shamin JR, Mohammad SJ, Adel MA. he
pharmacological features of bilirubin: the question of the century. Cell Mol
Biol Lett(2015).DOI: 10.1515/cmble-2015-0012
20. Salahuddin P, Fatima MT, Abdelhameed AS, Nusrat S, Khan RH. Structure of
amyloid oligomers and their mechanisms of toxicities: Targeting amyloid
oligomers using novel therapeutic approaches. European journal of
medicinal chemistry 2016.
21. Chaturvedi SK, Siddiqi MK, Alam P, Khan RH. Protein misfolding and
aggregation: Mechanism, factors and detection Process Biochemistry 2016.
22. P Salahuddin, MK Siddiqi, S Khan, AS Abdelhameed, Khan RH (2016)
Mechanisms of protein misfolding: Novel therapeutic approaches to protein-
misfolding diseases Journal of Molecular Structure 1123, 311-326
23. Siddiqi MK, Alam P, Chaturvedi SK, Shahein YE, RH Khan (2017)
Mechanisms of protein aggregation and inhibition. Front Biosci (Elite Ed).
2017 Jan 1;9:1-20
24. Alam P, Siddiqi MK, Chaturvedi SK and Khan RH (2017) Protein
aggregation: From background to inhibition strategies. International Journal of
Biological Macromolecules 103, 208- 219
CONFERENCE ATTENDED
1. Attended the International Lectin Meeting organized by Bose Institute
held at Darjeeling, May 24-30, 1990.
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2. Khan, R.H. Some properties of Cajanus cajan lectin. Proceeding of
61stAnnualmeeting of the Society of Biological Chemist held at CCMB,
Hyderabad, Dec. 1-23,1992.
3. Khan, R.H. and Salahuddin. A. Carbohydrate binding specificity of (Cajanus
cajan) lectin involvement of acidic group in lectin carbohydrate interaction.
Proceeding of IX Carbohydrate Conference held at CDRl, Lucknow, Nov
24-26, 1993.
4. Khan, R.H. and Salahuddin, P. and Salahuddin, A. Hydrogen ion titration
curve of Cajanus cajan lectin. Proceeding of the 9th Symposium of Protein
Society held atBoston, MA, USA, July 8-12,1995.
5. Zaidi, F.N., Johri, S.P., Khan, R.H.., Ahmad, A and Salahuddin, A. acid
induced unfolding and refolding of human serum albumin. Proceeding of
National Symposium of Molecular and cellular Biophysics held at New
Delhi, Feb. 18-21, 1996 at ITRC, Lucknow, Oct 6-8, 1995.
6. Khan, M., Khan, M.A., Khan, R.H. and Ahmad, S. pH dependence on
lectincarbohydrate interaction. Proceeding of National Symposium of
Molecular and Cellular Biophysics held at New Delhi, Feb. 18-21, 1996.
7. Khan, R.H. and Ahmad, A. The alcohol induced cooperative transition of -
sheet legume lectin into -helix. Proceedings of the National Symposium
on Radiation and Molecular Biophysics held at BARC/TIFR, Mumbai,
Jan, 21-24, 1998.
8. Khan, R.H. and Panda, A.K. Molten globule-structure in recombinant ovine
growthhormone. Proceeding of the 13th Symposia of Protein Society held at
Boston, SA, July 24-28, 1999.
9. Attended the symposium on Frontiers in Structural Biology held at
TIFR/GKVKCampus, Bangalore, Aug 25-27, 1999.
10. Khan, R.H. and Panda, A.K. Factors influencing the production of ovine
growthhormone in E.Coli. Proceedings of the 3rd European Symposium of
the Protein Society held at Germany, Sep. 19-22, 1999.
11. Naeem, A. and Khan, R.H. Interaction of Cajanus cajan root lectin with
rhizobial polysaccharides presented at the National Symposium on Stability
and Stabilization of Biomacromolecules held at Interdisciplinary
Biotechnology Unit, AMU, Aligarh, 2001.
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12. Haq, S.K. and Khan, R.H. Isolation and partial characterization of a
proteinase inhibit or from Cajanus cajan presented at the National
Symposium on Stability and Stabilization of Biomacromolecules held at
Interdisciplinary Biotechnology Unit, AMU, Aligarh, 2001.
13. Haq, S.K. and Khan, RH. Characterization of a proteinase inhibitor from
Cajanus cajan presented at the National Symposium on Biophysics held at
IIT Roorkee, Roorkee, 2003.
14. Haq, S.K., Rasheedi, S., Sharma, P., Ahmad, B. and Khan, R.H. Influence of
salts and alcohols on the conformation of partially folded state of stem
bromelain at low pH. International Symposium on Molecules, Machines
and Networks held at NCBS, Bangalore, January 6-9, 2004.
15. Khan JM, Khan, R.H. Poster presentation in VIII Annual research festival of
School of Life Science “Biospark 2010” held on March 11-12, 2010 at
Jawaharlal Nehru University New Delhi, India.
16. Ahmad E, Rabbani G, Khan RH. Mechanism of pollutant-induced
conformationalalterations in human serum albumin: a key to catalytic hetero
tropicallostericity causing non-microbial drug resistance Protein Science 19:
1- 286 (2010)” presented and published as abstract in the proceedings of 24th
Annual Symposium of ‘The Protein Society’ “Looking at Proteins:
Expanding Perspectives and New Technologies”, August 1-5, 2010. San
Diego, California (USA).
17. Khan JM, Khan, R.H. Poster presentation “1st Asia-Oceania conference on
Neutron Scattering” November 20-24, 2011. EPOCHAL TSUKUBA Tsukuba
International Congress Center TSUKUBA, Japan.
18. Rabbani G, Ahmad E, Zaidi N, Khan RH“Conformational transitions in
Candida antarctica lipase B: Characterization of an acid induced pre-molten
globule and molten globule state.” presented in Fifth International
Symposium on Recent Trends in Macromolecular Structure and
Function (5th ISRTMSF–2012) held on January 23-25 2012 at Centre of
Advanced Study in Crystallography and Biophysics, University of Madras,
Chennai, India.
19. Zaidi N, Khan, R.H. Contribution of sialylation on sodium dodecyl sulfate
induced unfolding of fetuin presented as poster at Fifth International
45
Symposium on Recent Trends in Macromolecular Structure and
Function (5th ISRTMSF–2012) held on January 23-25 2012 at Centre of
Advanced Study in Crystallography and Biophysics, University of Madras,
Chennai, India.
20. Zaidi N, Khan, R.H. Sudlow site II of HSA as a low affinity site for
Furosemide: Direct cause of impaired serum binding of furosemide in uremia
presented as poster at “Annual meeting of the Indian Biophysical Society
on the Jan 19-21, 2012 at Madras University, Chennai, India.
21. Rabbani G, Ahmad E, Zaidi N, Fatima S, Khan RH. “pH induced molten
globule state of Rhizopus niveus lipase is more resistant against thermal and
chemical denaturation than its native state presented as poster at “Annual
meeting of the Indian Biophysical Society on the Jan 19-21, 2012 at Madras
University, Chennai, India.
22. Khan JM, Khan, R.H. Poster presentation in international conference
“International Symposium on Protein Folding and Dynamics” National
Center for Biological Science (NCBS) held on October 15-17, 2012,
Bangalore India.
23. Zaidi N, Khan, R.H. “Biophysical insight into impaired furosemide binding
to human serum albumin in uremia” presented as poster at EMBO Global
Exchange Lecture Course “Structural and biophysical methods for
biological macromolecules in solution” on November 29–December 6,
2012 in Hyderabad, India.
24. Khan JM, Khan, R.H. “SDS Can Be Utilized as an Amyloid Inducer: A Case
Study on Diverse Proteins” presented at Interdisciplinary Biotechnology
Unit, Aligarh Muslim University Aligarh in 2012.
25. Chaturvedi SK., Khan,JM Khan RH, “Monomeric Banana Lectin at acidic
pH overrules conformational stability of its native dimeric” presented in.
International Symposium on Protein Folding and Dynamics” held on form
October 15-17, 2012 at Biochemical and Biophysical Research NCBS,
Bangalore.
26. Participate in the short term training programme on “Molecular Docking and
QSAR Analyses”. Organized by Bioinformatics Infrastructure facility
46
(BIF), Centre of Excellence in Bioinformatics (COEBI) Department of
Biochemistry, University of Lucknow, Lucknow (U.P.) India, held on
December 13-14, 2013.
27. Mohd Ishtikhar, Rabbani G, Khan RH“5-Fluoro-5’-deoxyuridine interaction
with Human Serum Albumin under Physiological and alkalosis Condition:A
Biophysical Investigation” presented in National Conference on “Recent
Trends in Protein Structural Biology” (NCRTPSB-2013) held on
December 16-18, 2013 at Interdisciplinary Research in Basic Sciences, Jamia
Millia Islamia, Jamia Nagar, New Delhi, India.
28. Khan JM, Khan, R.H. poster presentation in international conference “ESF-
EMBO Conference on Molecular Perspectives on Protein-Protein
Interactions” held on May 25-30, 2013 Polonia Castle in Pultusk, Poland
29. Alam P, Khan, R.H. “Effect of surfactant on structure and activity of
Rhizopus niveus lipase” presented (poster)in Recent trends in Free Radical
Biology held at Biochemistry department, Aligarh Muslim University, Aligarh
on February 2014.
30. Khan MV, Rabbani G, Khan RH “Fluoroalcohols mediated amyloid
induction in conalbumin (Ovatransferrin):A metalloproteinase from hen egg
white” presented in National Symposium cum workshop on “New Facet of
Biotechnology from Genes to Proteins” held on January 15-17, 2014 at
Interdisciplinary Biotechnology Unit, A.M.U., Aligarh, India.
31. Alam P, Khan, R.H. Interaction of anticancer Cytosine Beta D
arabinofuranoside with Human serum albumin: multiple technique approach
presented (oral) at Indian Biophysical Society meeting, New Delhi, India held
on February 2015.
32. Siddique K, Khan, R.H Comparative insight into the anionic and cationic
surfactants induced aggregation in hen egg white lysozyme presented at
national symposium on biophysics & golden jubilee meeting of the Indian
Biophysical Society held on 2015 at Centre for Interdisciplinary Research in
Basic Science, Jamia Millia Islamia, New Delhi.
33. Siddique K, Khan, R.H. Comparative insight into surfactants mediated
amyloidogenesis of lysozyme held on 2015 National symposium cum
47
bioinformatics workshop on macromolecular interactions in biology at
Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh.
34. Khan, R.H Attended The 3rd middle east molecular biology Congress and
Exhibition MEMBS, Doha (14-17 Nov 2016).
35. Zaidi N, Khan, R.H. Unveiling the inhibitory behavior of n-acetylneuraminic
acid against fibrillation of amyloidogenic proteins-a biophysical insight
presented and published as abstract in the proceedings of 30th Anniversary
Symposium of the Protein Society held on July 16-19, 2016 in Baltimore,
U.S.A.
36. Nusrat S, Khan RH, “Repositioning nordihydroguaiaretic acid as a potent
inhibitor of systemic amyloidosis and associated cellular toxicity” presented in
International conference on emerging trends in Biomedical Sciences held
on March 6-8, 2016 at Department of Biochemistry, A.M.U, Aligarh.
37. Zaman M, Khan RH. Biophysical insight of DNA induced aggregation of
stem bromelain. Biophysical Journal 110 (3), 220a. presented in Biophysical
Society 60th Annual meeting, held on 2016 at Los Angeles, California, USA
38. Zaman M, Khan RH. Biophysical insight into the anti-amyloidogenic
behavior of cysteine. Biophysical Journal 112 (3), 365a. presented in
Biophysical Society 61st Annual meeting held on 2017 at New Orleans,
Louisiana, USA.
39. Alam P, Khan, R.H. Cu (II) binding modulate the aggregation behaviour of
Y145Stop variant of human prion protein presented at Department of
Chemistry and Biochemistry, The Ohio State University, USA held on
December 2017.
Invited lecture(s) delivered in India/abroad and/or chaired any scientific
International Conference.
1. Invited as a key note speaker in The Fifth International Conference for Young
Scientists in Basic and Applied Sciences, “Recent Approaches in Basic and
Applied Sciences”, Faculty of Science-Assiut University Assiut-Egypt Oct
29th-Nov 1st ,2016.
48
2. Invited lecture: The First International Conference on Multidisciplinary
Research Ain El-Sokhna-Egypt, (28th-31st of October 2015).
3. Given oral presentation on “Unraveling comparative anti-amyloidogenic
behavior of pyrazinamide and d-cycloserine: a mechanistic biophysical
insight” in 2nd International Symposium on Protein Folding and Dynamics,
November 5-7, 2014.Bangalore.
4. Participated in DST Sponsored “Mass Spectrometry for Proteomics”
Workshop held on 6-8th Aug, 2014, AIRF, JNU, New Delhi –110067, India.
5. Given short term Lecture on “Plant Tissue Culture and Molecular Biology” in
Dept of Botany, AMU, Aligarh on 30thJune 2013.
6. Chair the session at VIIIth National Conference in Biotechnology, Biodiversity
and Environment. Recent Advancements in Biodiversity conservation,
Biotechnology and Environmental Management Research, 19-20th April 2013,
Organized By Department of Botany and Biotechnology, Govt. New Science
College, Rewa (Govt. MS. Galwalkar College, Rewa, MP).
7. Given invited talk “Protonation favors Aggregation of Lysozyme with SDS”
at VIIIth National Conference in Biotechnology, Biodiversity and
Environment. Recent Advancements in Biodiversity conservation,
Biotechnology and Environmental Management Research, 19-20th April 2013,
Organised By Department of Botany and Biotechnology, Govt. new Science
College, Rewa ( Govt. MS. Galwaltar College Rewa MP).
8. Delivered Lectures in the Dept of Biotechnology Amarkartak University, MP
from 27-28th March 2012.
9. Given invited lecture and engaged in practical classes in DBT- Sponsored
short term training course (STTC) on “Proteomic techniques in
Biotechnology” at Kumaraguru College of Technology, Coimbatore from 25-
26th Nov 2010.
10. National symposium on Biophysics: Trends in Biomedical Research Feb 13-
15, 2007.
WORKSHOPS/ SYMPOSIUM
1. Attended workshop on "Protein Bioinformatics and Genomics" held at
TIFR/ GKVK Campus, Bangalore, Aug, 28, 1999.
49
2. Attended workshop on" Sequence analysis and Molecular Modeling" held
at J.N.U., New Delhi, and Dec 17-18, 1998.
3. Attended National Symposium on Biophysics ‘Biophysics in Medicine and
Biology’ under the aegis of Indian Biophysical Society. November 15-17,
2007, held at Punjab University, Chandigarh.
4. Attended National Symposium on Biophysics ‘Trends in Biomedical
Research’ under the aegis of Indian Biophysical Society. 13th -15thFebruary,
2007, held at Indian National Science Academy, New Delhi.
PERSONAL INFORMATION
Date of Birth: December 25,1965
Sex: Male
Nationality: Indian
Marital Status: Married
Present Position: Professor
Interdisciplinary
Biotechnology Unit
A.M.U., Aligarh 202 002
Telephone: 91-571-2720388
Telefax: 91-571-2721776
Mobile: 91-9997778669
Permanent Address: 431/227 Katghar, Allahabad
211 003