CURRICULUM VITAE

KEVIN L. SCHALINSKE Professor Department of Food Science and Human Nutrition Iowa State University 220 MacKay Hall Ames, IA 50011-1061 Phone: 515-294-9230 Fax: 515-294-6193 Email: kschalin@iastate.edu EDUCATION University of Wisconsin – Madison B.S. 1983 Molecular Biology University of Wisconsin – Madison M.S. 1988 Nutritional Sciences University of Wisconsin – Madison Ph.D. 1992 Nutritional Sciences University of Wisconsin – Madison Postdoctoral 1992-1997 Nutritional Sciences RESEARCH AND PROFESSIONAL EXPERIENCE 1983 - 1985 Research Specialist, Department of Nutritional Sciences, University of

Wisconsin – Madison, Madison, WI (Dr. Earl Shrago, P.I.). 1985 - 1992 Research Assistant, Department of Nutritional Sciences, University of

Wisconsin – Madison (Dr. Robert D. Steele, mentor). 1988 - 1989 Teaching Assistant, Department of Nutritional Sciences, University of

Wisconsin – Madison. 1992 - 1996 Research Associate/Postdoctoral Fellow, Department of Nutritional Sciences,

University of Wisconsin – Madison (Dr. Richard S. Eisenstein, mentor). 1996 - 1997 Assistant Scientist, Department of Nutritional Sciences, University of

Wisconsin – Madison. 1997 - 1999 Scientist, Department of Pathology and Experimental Toxicology, Parke-Davis

Pharmaceutical Research Division, Ann Arbor, MI. 1998 - 1999 Adjunct Faculty, Department of Environmental and Industrial Health (EIH),

Human Nutrition Program, University of Michigan, Ann Arbor, MI. 1999 - 2004 Assistant Professor, Department of Food Science and Human Nutrition (FSHN),

Iowa State University, Ames, IA. 2000 - present Faculty Member, Interdepartmental Program in Toxicology (TOX), Iowa State

University, Ames, IA.

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2000- present Faculty Member, Program in Molecular, Cell, and Developmental Biology (MCDB), Iowa State University, Ames, IA.

2004 - 2006 Director of Graduate Education, Department of FSHN, Iowa State University, Ames, IA.

2004- 2010 Associate Professor, Department of FSHN, Iowa State University, Ames, IA. 2006- 2013 Director of Graduate Education, Interdepartmental Graduate Program in Nutritional Sciences (IGPNS), Iowa State University, Ames, IA. 2010 - present Professor, Department of FSHN, Iowa State University, Ames, IA. TEACHING EXPERIENCE University of Wisconsin - Madison (Teaching Assistant) • Nutritional Sciences 132, "Nutrition Today", undergraduate course. • Nutritional Sciences 332, "Human Nutritional Needs", undergraduate course. University of Michigan - Ann Arbor (Adjunct Faculty Lecturer) • EIH 631, "Advanced Nutrition", graduate course. Iowa State University (Assistant/ Associate/ Full Professor) • FSHN 203, “Contemporary Issues in Food Science and Human Nutrition”, undergraduate course.

• FSHN 261, "Fundamentals of Human Nutrition", undergraduate course. • FSHN 360, "Advanced Human Nutrition and Metabolism", undergraduate. • FSHN 467, “Molecular Basis of Nutrition in Disease Prevention”, undergraduate. • FSHN 480, “Professional Seminar in Food Science & Human Nutrition”, undergraduate. • FSHN 492, “Research Concepts in Nutrition”, undergraduate. • FSHN 502, “Advanced Food Science – Chemistry”, graduate. • FSHN 612, “Food Lipids”, graduate. • FSHN 695, “Grant Writing Experience”, graduate.

• HON 322G, “Understanding the Human Genome: Implications in Health, Disease, and Bioethics”, undergraduate Honors seminar.

• NUTRS 501, "Biochemical and Physiological Basis of Nutrition: Macronutrients", graduate.

• NUTRS 502 " Biochemical and Physiological Basis of Nutrition: Vitamins and Minerals", graduate.

• NUTRS 504, “Nutrition and Epigenetic Regulation of Gene Expression”, graduate.

• TOX 504, "Seminar in Toxicology", graduate.

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HONORS 1979 Recipient of a Western Publishing Co Foundation Academic Scholarship 1990 Recipient of an American Institute of Nutrition predoctoral fellowship 1991 Finalist in the American Institute of Nutrition Graduate Student Research Awards 1993 Postdoctoral fellowship from the USDA/CSRS NRI Competitive Grants Program 2005 Named a “Best Professor at Iowa State University” by Residence Hall survey. 2006 Recipient of the American Society for Nutrition (ASN) E.L.R. Stokstad Award 2006 Outstanding Faculty Member, All-Greek Academic Recognition Ceremony, Iowa

State University 2007 Nominated for Faculty of the Year, College of Human Sciences, VEISHA 2007

2007 Outstanding Faculty Member, All-Greek Academic Recognition Ceremony, Iowa State University

2008 Nominated for Mid-Career Research Award, College of Agriculture and Life Sciences (CALS).

2008 Nutrition consultant, “Modern Marvels” television show titled “The Egg”. 2010 Selected participant in the Dannon Institute Academic Mid-Career Nutrition

Leadership Institute. 2012 Influential Faculty Member, Greek Community Luncheon and Program 2012 Recipient of the CALS Outstanding Achievement in Teaching Award. 2012 Recipient of the Board on Human Sciences Undergraduate Research Mentor

Award, presented at the APLU Annual Conference. 2013 Recipient of the Iowa State University (ISU) Foundation Award for Outstanding

Achievement in Teaching.

PROFESSIONAL ACTIVITIES

Journal Reviewer

Annals of Nutrition and Metabolism Antioxidants and Redox Signaling

The American Journal of Clinical Nutrition The American Journal of Physiology Cell Physiology

The American Journal of Physiology: Endocrinology & Metabolism The American Journal of Physiology: Gastrointestinal & Liver Physiology The American Journal of Physiology: Heart & Circulatory Physiology The American Journal of Physiology: Physiological Genomics The American Journal of Physiology: Regulatory, Integrative and Comparative

Physiology Biochemical Journal Biochimica Biophysica Acta BioFactors British Journal of Nutrition Cancer Epidemiology, Biomarkers & Prevention Cancer Letters

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Cancer Research Cardiovascular Diabetology Cardiovascular Toxicology Chemico-Biological Interactions Clinical Cancer Research Current Nutrition Reviews

• Editorial Board, 2004 - present Diabetes Diabetes Care Diabetes/ Metabolism Research and Reviews Experimental Cell Research The FASEB Journal Gene Hepatology Hypertension Research International Journal of Obesity Nutrition and Cancer: An International Journal Nutrition Research Nutrition Reviews

• Contributing Editor, 2002 – 2012 • Editorial Board, 2012 - present

Journal of Agricultural and Food Chemistry Journal of the American College of Nutrition Journal of Biological Chemistry Journal of Diabetes and its Complications Journal of the European Academy of Dermatology and Venereology Journal of Lipid Research Journal of Neuroscience Methods The Journal of Nutrition

• Editorial Board, 2002 - 2008 • Guest Associate Editor, 2009 • Guest Associate Editor, 2010 • Guest Associate Editor, 2011 • Guest Editor for Supplements, 2012 – 2013 (new permanent position with JN)

Journal of Nutritional Biochemistry Molecular and Cellular Biochemistry Molecular Genetics and Metabolism Nutrition, Metabolism, & Cardiovascular Diseases PLoS One Trends in Endocrinology and Metabolism

Textbook Reviewer Reviewer, Introductory Nutrition Textbooks (McGraw-Hill & Benjamin Cummings) Reviewer/ participant, Nutrition textbook development workshop (Wadsworth)

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Reviewer, Advanced Nutrition and Human Metabolism (4th ed.), Gropper, Smith, & Groff, Thomson-Wadsworth

Reviewer, Advanced Nutrition and Human Metabolism (5th ed.), Gropper, Smith, & Groff, Thomson-Wadsworth

Developed Instructor Study Guide for Advanced Nutrition and Human Metabolism, 5th edition (Wadsworth).

Reviewer, Nutritional Sciences: From Fundamentals to Food (2nd ed.), (Thomson-Wadsworth)

Reviewer, Nutritional Sciences: From Fundamentals to Food (3rd ed.), (Thomson-Wadsworth)

Developed and contributed material for online critical thinking database, InfoTrac College Edition (Thomson-Wadsworth).

Reviewer, Advanced Nutrition and Human Metabolism (6th ed.), Gropper, Smith, & Groff, Thomson-Wadsworth

Developed/ revised Instructor Study Guide for Advanced Nutrition and Human Metabolism, 6th edition (Wadsworth).

Reviewer, Nutritional Sciences: From Fundamentals to Food (4th ed.), (Thomson-Wadsworth)

Book Reviewer

Reviewer, The effects of diet on epigenetic processes, in: Handbook of Epigenetics: The

New Molecular and Medical Genetics (ed. Tollefsol, T.), Elsevier. Grant Reviewer

Review Panel Member for USDA NRI Competitive Grants Program (2001) Reviewer for Department of Veterans Affairs Medical Research Program (2002) Reviewer for U.S. Civilian Research and Development Foundation (2003) Reviewer (Ad Hoc) for USDA NRI Competitive Grants Program (2002, 2004) Reviewer, Integrative Nutrition and Metabolic Processes (INMP) Study Section, National

Institutes of Health (2007) Reviewer, ZRG1 EMNR-G (Nutrition) Study Section, National Institutes of Health

(2008) Reviewer, Cellular Aspects of Diabetes and Obesity (CADO) Study Section, National

Institutes of Health (2009) Reviewer, Endocrinology, Metabolism, Nutrition, and Reproductive Sciences (EMNR)

Study Section, ZRG1 EMNR-C (58) R - RFA OD-09-003 Challenge Grants Panel 15, National Institutes of Health (2009)

Reviewer, ZRG1 EMNR-B (95) S – Molecular Obesity and Diabetes ARRA CR, National Institutes of Health (2009)

Reviewer, Qatar National Research Foundation (2011) Reviewer, National Pork Board (2011) Reviewer, Biotechnology and Biological Sciences Research Council (BBSRC), United

Kingdom (2011) Reviewer, National Pork Board (2012)

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Reviewer, USDA/ NIFA Small Business Innovative Research Program, 2012 Review Panel Member, American Heart Association, Basic Cell, Genetics and

Epigenetics (GE) 2 Peer Review Study Group (2012-2014) Reviewer, Integrative Nutrition and Metabolic Processes (INMP) Study Section, National

Institutes of Health (2012) Reviewer, National Pork Board, Round 2 (2012) Reviewer, Biotechnology and Biological Sciences Research Council (BBSRC), United

Kingdom (2012) Reviewer, National Pork Board, Round 2 (2013) Reviewer, USDA National Needs Fellowship (2013) Reviewer, Research Grants Council, Collaborative Research Fund, Hong Kong (2013) Regular Member, Integrative Nutrition and Metabolic Processes (INMP) Study Section,

National Institutes of Health (2013-2017)

Project Reviewer External Reviewer, USDA AES multi-state project W1002 (2008) External Reviewer, USDA AES multi-state project W3002 (2013)

Program Reviewer

External Reviewer, Graduate Program in Nutritional Science, Southern Illinois

University, 2011 Exam Development in Nutrition, Certification Management Services, 2012

Faculty Reviewer

Reviewer, Promotion & Tenure, Assistant to Associate Professor, Department of Food Science and Human Nutrition, University of Illinois, Champaign-Urbana, 2012

MEMBERSHIP AND ACTIVITIES IN PROFESSIONAL SOCIETIES American Association for the Advancement of Science (AAAS) American Diabetes Association (ADA)

American Society for Biochemistry and Molecular Biology (ASBMB) American Society for Nutrition (ASN)

Member, ASN Industry Liaison Committee (1997) Co-chair, Vitamin A & Retinoids, ASN minisympoium, Experimental Biology,

Washington, D.C. (2002) Advisor, Student Research Interest Section (2004-2008) Chair, ASN Awards Committee, Mead Johnson Award (2006) Chair, B-vitamins and Methyl Group Metabolism, ASN minisymposium,

Experimental Biology, Washington, D.C. (2007) Jury member, two ASN award committees (2007) ASN Nutrition Sciences Council Task Force (2007)

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Chair, ASN Nutritional Sciences Council Task Forces on research translation (2008) Chair-elect, ASN Nutrient-Gene Interaction Research Interest Section (2009 - 2010) Guest Editor, ASN Symposium on Epigenetics, The Journal of Nutrition (2009) Chair, ASN Nutrient-Gene Interaction Research Interest Section (2010 - 2011) Guest Editor, ASN Symposium on Systems Genetics in Nutrition and Obesity, The

Journal of Nutrition (2010) Co-chair, Diet and DNA Methylation, ASN minisymposium, Experimental Biology,

Washington, D.C. (2011) Guest Editor, ASN Symposium on Heart Healthy Omega-3s for food: Stearidonic

Acid (SDA) as a sustainable choice, The Journal of Nutrition (2011) Member, Nutrient-Gene Interaction Advisory Committee (2011-2012) Chair, Vitamins and One Carbon Metabolism, ASN minisymposium, Experimental

Biology, San Diego (2012) Chair, Maternal Programming of Gene Expression, ASN minisymposium,

Experimental Biology, San Diego (2012) Guest Editor, The Journal of Nutrition (permanent position for all supplements and

symposium submitted for publication) (2012 - 2013) Co-chair and invited speaker, Nutritional Epigenomics: A Portal to Disease

Prevention, ASN Symposium, Experimental Biology, Boston (2013) Member, ASN Publications Management Committee (2013-2016) Director-elect, Research Interest Sections, ASN (2013-2014) Director, RIS, ASN (2014-2016) Member, Board of Directors, ASN (2014-2016) Past Director RIS, ANS (2016-2017)

Society for Experimental Biology and Medicine (SEBM) RESEARCH GRANTS Completed 1999 - 2002 USDA Special Grant - Center for Designing Foods to Improve Nutrition "Retinoid-induced modulation of hepatic methyl group metabolism:

induction of a folate- and lipotrope-deficient condition" PI: Schalinske, K.L.

$65,183

2001 - 2003 American Institute for Cancer Research "Folate-retinoid interactions: implications for cancer development" PI: Schalinske, K.L. $83,559 2001 - 2004 USDA NRI Competitive Grants Program (New Investigator Award) "Folate-retinoid interactions: implications in liver disease" PI: Schalinske, K.L. $181, 967

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2002 - 2003 University Research Grant, Iowa State University “Developmental regulation of glycine N-methyltransferase and methyl

group metabolism: implications for birth defects” PI: Schalinske, K.L. $16,240

2003 - 2004 USDA Special Grant - Center for Designing Foods to Improve Nutrition “Effect of soy protein components in reducing cardiovascular disease risk in postmenopausal women”

PI: Reddy, M.B. CoPI: Schalinske, K.L. (20%) CoPI: Kohut, M. $27,286 2003 - 2004 USDA Special Grant - Center for Designing Foods to Improve Nutrition

“Do isoflavones extracted from soy modulate homocysteine metabolism to enhance bone mineral density in folate sufficient postmenopausal women”

PI: Alekel, D.L. CoPI: Schalinske, K.L. (20%) $44,132 2003 - 2005 Cancer Research and Prevention Foundation “Chronic perturbation of methyl group metabolism by retinoid

compounds” PI: Schalinske, K.L. $70,000

2004 - 2006 American Diabetes Association “Perturbation of methyl group metabolism by diabetes and retinoid

compounds” PI: Schalinske, K.L. $292,539 2006 - 2007 W.F. Martin Fund Nutritional Sciences Council, Iowa State University “Treatment of diabetes with vitamin D: Is restoring normal metabolism of

methyl groups and homocysteine involved?” PI: Schalinske, K.L. $7,600

2006 - 2007 Egg Nutrition Center “Analysis of Choline Intake for At-Risk Populations in the U.S.” PI: Jensen, H. H. CoPI: Carriquiry, A. CoPI: Schalinske, K.L. (10%)

$47,088

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2006 - 2008 USDA Special Grant – Center for Designing Foods to Improve Nutrition “Modulation of iron homeostasis by vitamin A: implications for vitamin A-

deficiency anemia” PI: Schalinske, K.L. (90%) CoPI: Reddy, M.B. $65,701 2007 - 2009 Iowa Egg Council / Egg Nutrition Center / American Egg Board

“Egg lecithin and egg protein: a dietary strategy to reduce cardiovascular disease risk” PI: Schalinske, K.L. (90%) CoPI: Wang, T. $92,146

2008 – 2009 W.F. Martin Fund Nutritional Sciences Council, Iowa State University “Treatment of hyperhomocysteinemia with genistein supplementation” PI: Schalinske, K.L. $10,500 2007 - 2009 American Heart Association

“Diabetes and cardiovascular disease: the role of epigenetic regulation and dietary methyl donors” PI: Schalinske, K.L. $143,000

2008 – 2010 USDA Special Grant – Center for Designing Foods to Improve Nutrition “Relation between vitamin D homeostasis and disruption of one-carbon

metabolism in type 2 diabetes” PI: Schalinske, K.L. (50%) CoPI: Rowling, M.J. $60,000 2006 - 2011 Nutrition Hatch Renewal, USDA/ CSREES “Improving Human Foods: Functionality, Selection and Nutrition” PI: Schalinske, K.L.

CoPI: Alekel, D.L., Birt, D., Boylston, T., Carriquiry, A., Hansen, C., Hendrich, S., Love, M., MacDonald, R., Murphy, P., Nikolau, B., Reddy, M., Spurlock, M., White, W.

2008 – 2011 National Institutes of Health (NICHD) “The etiology of birth defects: implications for GNMT expression” PI: Schalinske, K.L. $149,966

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2010 – 2011 United Soybean Board, Soy Health Research Program “Prevention of breast cancer: impact of dietary soy and genistein” PI: Schalinske, K.L. (50%) CoPI: Rowling, M.J. (50%) $20,000 2010 – 2012 College of Human Sciences, Intramural Collaborative Seed Grant Program “Impact of exercise on optimizing methyl group and homocysteine

metabolism” PI: Schalinske, K.L. (90%) CoPI: Kohut, M.L. $24, 496

2010 – 2012 Nutrition and Wellness Research Center, ISU – Incentive Grant “Impact of exercise on homocysteine balance” PI: Schalinske, K.L. (90%) CoPI: Kohut, M.L. $5,000

Current

2011 – 2013 Plant Sciences Institute “Resistant starch in type 1 diabetes” PI: Schalinske, K.L. $73,862 2011 – 2013 College of Human Sciences, Intramural Collaborative Seed Grant Program “Therapeutic retinoid usage: benefit of SAMe supplementation” PI: Schalinske, K.L. CoPI: Kohut, M.L. $25,000 2012 – 2014 Egg Nutrition Center/ American Egg Board “Type 2 diabetes and vascular disease: impact of dietary egg

consumption” PI: Schalinske, K.L. $178, 846 (year 2 funding contingent on year 1 progress) 2013 – 2018 USDA National Needs Fellowship “Transdisciplinary graduate training program in childhood obesity using

a socio-ecological model” PI: Schalinske, K.L. $238,000

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MENTORED STUDENTS AND OTHER PROFESSIONALS

1999 - 2004 Matthew J. Rowling, Ph.D. in Nutrition, currently an Assistant Professor in the Department of Food Science & Human Nutrition, Iowa State University.

Recipient of the ASN/ Proctor & Gamble Research Award (2001), the Nutritional Sciences Council David R. Griffith Research Award (ISU), and the ISU Research Excellence Award (2004).

2001 - 2003 Marlies K. Ozias, M.S. in Nutrition and Toxicology, currently a

Research Scientist at the University of Kansas Medical Center. 2001 - 2002 Mary H. McMullen, Research Associate I, most recently received

M.S. in Nutrition from the University of Minnesota. 2002 - 2004 Virginia E. Knoblock, M.S. in Nutrition. 2002 - 2008 Kristin M. Nieman, M.S. in Nutrition (2004) and Ph.D. in

Nutritional Sciences (2008); currently a postdoctoral fellow at the University of Chicago.

Recipient of an ASN Predoctoral Fellowship (2005); recipient of the David R. Griffith Award (2008); and recipient of the ISU Research Excellence Award (2008).

2004 - 2006 Cara A. Hartz, M.S. in Nutritional Sciences, currently a Ph.D.

candidate in Pharmaceutical Sciences at the University of Michigan.

Recipient of the Nutritional Sciences Council David R. Griffith Award (ISU) in 2006.

2004 - 2006 Stacy E. Schroeder, M.S. in Nutritional Sciences, R.D., currently a

Global Clinical Research Scientist at Hollister Incorporated, Chicago, IL.

Recipient of the Society for Experimental Biology and Medicine Young Investigator Award (2006).

2005 - 2009 Kelly T. Williams, Ph.D. in Nutritional Sciences; currently a

postdoctoral associate at HudsonAlpha Institute for Biotechnology, Huntsville, AL.

Recipient of an ASN Predoctoral Fellowship (2007) and was the student representative to the ASN Vitamins and Minerals Research Interest Section (2006-2007). Recipient of the Society for Experimental Biology and Medicine Young Investigator Award (2009) and the ISU Research Excellence Award (2009). Poster competition winner, ASN Nutrient-Gene Interaction Research Interest Section (2009).

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2007 - 2010 Eric B. Nonnecke, M.S. degree in Nutritional Sciences; currently a

Ph.D. candidate at the University of California – Davis. Recipient of a Norman Borlaug Best Poster Award (2006, 2008, 2009). Poster competition winner, ASN Vitamins and Minerals Research Interest Section (2009) and elected as its student representative (2009-2010).

2008 - 2010 Joshua C. Neuman, M.S. degree in Nutritional Sciences; currently

a Ph.D. candidate at the University of Wisconsin - Madison. Recipient of the 2010 American Egg Board/ Egg Nutrition Center

Doctoral Fellowship (award declined). Recipient of the ISU Research Excellence Award (2010) and a finalist in the ASN NSC Graduate Student Research Competition (2011).

2011 - 2013 Anne L. Smazal, M.S. degree in Nutritional Sciences. Recipient of

a Research Excellence Award from ISU (2013) and the David R. Griffith Award (2013). Currently a medical student at the University of Iowa.

2012 – present Alysse Anderegg, B.S./ M.S. candidate in Diet and Exercise. 2012 – present Korey Van Wyk, M.S./ Ph.D. candidate in Nutritional Sciences.

UNIVERSITY COMMITTEES Department/ Program 1999 - 2002 Graduate Admissions Committee, Department of FSHN 1999 - 2002 PhD Examination Committee, FSHN 1999 - 2004 Graduate Recruitment Task Force / Committee, FSHN 2000 Search Committee, FSHN Technical Support position

2001 - 2004 Graduate Admissions Committee, Program in MCDB. 2001 - 2002 Search Committee, faculty position in Chemical Engineering /

Food Science (Biotech representative) 2001 - 2002 Search Committee, faculty position in Microbiology / Veterinary

Medicine (Biotechnology Council Representative) 2002 - 2004 Equipment Task Force / Committee, FSHN

2002 Search Committee, Assistant Professor faculty position in Nutrition, FSHN

2002 - 2003 Search Committee, faculty position in Animal Sciences / Poultry Nutrition (Biotechnology Council Representative).

2002 - 2004 Graduate Program Committee, FSHN 2003 - 2004 Search Committee, faculty position in Chemical Engineering

(Biotechnology Council Representative)

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2003 - 2004 Chair, Graduate Recruitment Committee, FSHN 2004 - 2005 Undergraduate Recruitment Task Force, FSHN 2004 - 2006 Director of Graduate Education (DOGE), FSHN 2004 - 2006 Graduate Admissions Committee, FSHN 2004 - 2013 Admissions Committee, BS/MS in Diet and Exercise Program 2006 Search Committee, Associate Professor/ Director of Dietetics 2006 - 2007 RD/MPH Task Force, FSHN

2006 Chair, Search Committee, two faculty positions in FSHN 2006 - 2013 Chair and DOGE, Interdepartmental Graduate Program in

Nutritional Sciences (IGPNS) 2006 - 2013 IGPNS, Recruitment and Admissions Committee 2006 - 2013 Graduate Education Committee (ex officio), FSHN 2007 - 2008 Departmental Advisory Committee, FSHN 2007 - 2008 Chair, Search Committee, three faculty positions in FSHN 2007 - 2008 Search Committee, Accountant II position in FSHN 2008 Search Committee, Grant Manager position in FSHN 2008 Search Committee, Secretary II/III position in FSHN 2008 - 2009 Awards Committee, FSHN 2009 - 2010 Chair, Faculty Review Committee, FSHN 2009 - 2010 Safety and Facilities Committee, FSHN 2009 - 2010 Advisor, Nutrition Club, FSHN 2009 - 2011 Faculty Review Committee, FSHN 2010 - 2013 Faculty Advisor, Interdepartmental Graduate Student Club 2010 - 2013 Curriculum Committee, BS/MS in Diet and Exercise Program 2011 Search Committee, Grant Coordinator position in FSHN 2011 - 2014 Member (Chair, 2013), Promotion & Tenure Committee, FSHN

2011 - 2013 Member, Departmental Advisory Committee, FSHN 2012 – 2013 Co-chair, Search Committee, Assistant/ Associate Professor

positions (2), FSHN 2013 Member, Search Committee, Assistant Professor in Global

Nutrition College

2002 - 2005 Honors and Scholarships Committee, College of Family and Consumer Sciences (CFCS)

2004 - 2005 Curriculum Committee, CFCS 2004 - 2006 Honors Curricular Program Committee, College of Agriculture

2004 - 2013 Research and Graduate Education Advisory Committee, CFCS/ CHS (College of Human Sciences)

2004 - 2013 Admissions Committee, Master of Family and Consumer Sciences (MFCS Comprehensive) degree program 2005 - 2008 Biohazards and Public Safety Committee, College of Human

Sciences (CHS) 2009 - 2011 CHS Honors Program Committee 2011 - present Chair, CHS Honors Program Committee

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2009 - present CALS Honors Program Committee 2011 - 2014 Member, CALS Promotion & Tenure Advisory Committee (2012 – Vice-chair; 2013 – Chair) 2012 - 2013 Chair, CHS Caucus (Faculty Senate) 2012 - 2013 Budget Advisory Committee, CHS

University 2000 - 2005 Nutritional Sciences Council, Research Committee

2000 - 2006 Nutritional Sciences Council, Education Committee 2001 - 2004 Biotechnology Council, CFCS representative 2002 – 2005 Chair, Nutritional Sciences Council Research Committee 2002 - 2006 Nutritional Sciences Council, Modern Views in Nutrition Seminar Committee

2004 - 2005 Graduate Curriculum and Catalog Committee, Iowa State University (CFCS representative)

2005 - 2006 Member, Faculty Senate Research Policy Committee 2005 - 2011 Radiation Safety Compliance Committee, Iowa State University

2008 - 2009 Search Committee, Director of Biotechnology 2008 - present Advisory Board, Nutritional Sciences Council 2009 - 2010 Chair, Modern Views in Nutrition seminar committee 2009 - 2013 Senator (department), Faculty Senate 2010 - 2011 Member, Nutrition and Wellness Research Center (NWRC),

Symposium Committee 2010 - present Member, Faculty Senate, Resource Policies and Allocations (RPA)

Council 2010 - 2013 Member, Operations Committee for the NWRC 2011 Member, One Health Strategic Leadership Committee 2011 - 2014 Member, Institutional Animal Care and Use Committee, 2011 - 2013 Chair, Nutritional Sciences Council ASN Awards Committee 2011 - present Member, University Honors Committee. 2011 - 2012 Member, Search Committee, Assistant Director of the Honors

Program, University Honors Committee. 2012 - present Member, Faculty Senate Executive Board 2012 – 2013 Member, Faculty Senate Committee on Committees 2012 – 2013 Member, Faculty Senate Representative Committee 2012 – 2013 Member, Graduate Student Learning Community, Graduate

College 2013 Reviewer, Cyclone Grants, Graduate College 2013 – 2014 President-elect, Faculty Senate 2013 – 2014 Chair, Faculty Senate Committee on Committees 2013 – 2014 Chair, Faculty Senate Representative Committee 2013 – 2014 Member, Advisory Board, Center for Excellence in Teaching and

Learning (CELT) 2013 – 2-14 Member, Faculty Senate Leadership Committee 2013 – 2014 Member, Search Committee for the Vice President for Research

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2014 – 2015 President, Faculty Senate 2015 – 2016 Past President, Faculty Senate

INVITED SEMINARS AND PRESENTATIONS

1993 University of Illinois, Division of Nutritional Sciences 1995 Texas A&M University, Department of Animal Sciences, Faculty of Nutrition 1995 University of Wisconsin, Department of Chemistry and Biochemistry 1996 University of Wisconsin – Madison, Department of Nutritional Sciences 1996 University of Missouri – Columbia, Nutritional Sciences Group 1997 Parke-Davis Pharmaceutical Research Division, Department of Pathology and

Experimental Toxicology 1997 University of North Carolina – Greensboro, Department of Food, Nutrition, &

Food Service Management 1997 University of Michigan, Department of Environmental and Industrial Health,

Human Nutrition Program 1998 University of Wisconsin – Green Bay, Department of Human Biology 1998 University of Missouri – Columbia, Nutritional Sciences Group 1998 Iowa State University, Department of Food Science and Human Nutrition

1999 Iowa State University, Department of Plant Pathology 1999 University of Minnesota, Department of Food Science and Nutrition 2001 Iowa State University, Interdepartmental Program in Toxicology 2001 Iowa State University, Program in Molecular, Cell, and Developmental Biology 2004 University of Illinois, Division of Nutritional Sciences 2005 Des Moines University - Osteopathic Medical Center 2005 Iowa State University, Department of Biochemistry, Biophysics, and Molecular Biology 2006 FASEB Summer Research Conference on “Folate, Vitamin B12 & One-carbon

Metabolism” 2006 Panel member for “Choices: Returning to Academia”, Preparing Future Faculty

program, Iowa State University 2006 Panel member for “Building a Career as a Researcher and Scholar”, a session sponsored by the College of Human Sciences, Iowa State University

2007 American Heart Association, Industry Nutrition Advisory Panel, annual meeting 2009 Iowa State University, Department of Food Science and Human Nutrition 2011 Iowa State University, Department of Food Science and Human Nutrition 2012 University of Nebraska, Lincoln, Nebraska Gateway for Nutrigenomics Seminar

Series

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PUBLICATIONS University of Wisconsin – Research Technician (1983 – 1985) Bremer, J., Woldegiorgis, G., Schalinske, K. & Shrago, E. (1985) Carnitine

palmitoyltransferase. Activation by palmitoyl-CoA and inactivation by malonyl-CoA. Biochim. Biophys. Acta 833:-9-16.

Strieleman, P.J., Gribskov, C.L., Kemnitz, J.W., Schalinske, K.L., Claude, P., Parada, I., Shrago, E. & Swick, R.W. (1985) Brown adipose tissue from fetal rhesus monkey (macaca mulatta): morphological and biochemical aspects. Comp. Biochem. Physiol. 81B: 393-399.

Strieleman, P.J., Schalinske, K.L. & Shrago, E. (1985) Partial purification and functional reconstitution of GDP sensitive brown adipose tissue mitochondria uncoupling protein using octyl glucoside. Biochem. Biophys. Res. Comm. 127: 509-516.

Strieleman, P.J., Schalinske, K.L. & Shrago, E. (1985) Fatty acid activation of the reconstituted brown adipose tissue mitochondria uncoupling protein. J. Biol. Chem. 260: 13402-13405.

Shrago, E., MacDonald, M.J., Woldegiorgis, G., Bremer, J. & Schalinske, K. (1986) in Clinical Aspects of Human Carnitine Deficiency ( Borum, P.R., ed.), pp. 28-37, Pergamon Press, New York.

University of Wisconsin – Graduate Research Assistant (1985 – 1992) Schalinske, K.L. & Steele, R.D. (1989) Quantitation of carbon flow through the hepatic folate-

dependent one-carbon pool in rats. Arch. Biochem. Biophys. 271: 49-55. Schalinske, K.L.& Steele, R.D. (1991) 13-cis-Retinoic acid alters methionine metabolism in

rats. J. Nutr. 121: 1714-1719. Schalinske, K.L. & Steele, R.D. (1992) Variations in S-adenosylmethionine, S-

adenosylhomocysteine, and adenosine concentrations in rat liver. BioFactors 3: 265-268. Schalinske, K.L. & Steele, R.D. (1993) 13-cis-Retinoic acid and hepatic steatosis in rats.

Biochem. Pharmacol. 46: 319-325. Schalinske, K.L. & Steele, R.D. (1996) Carbon flow through the hepatic folate-dependent one-

carbon pool is not altered in vitamin A-deficient rats. J. Nutr. 126: 668-672. Schalinske, K.L. & Steele, R.D. (1996) Quantification of the carbon flow through the hepatic

folate-dependent one-carbon pool using radiolabeled histidine: effect of altered thyroid and folate status. Arch. Biochem. Biophys. 328: 93-100.

Schalinske, K.L. & Steele, R.D. (1996) Methotrexate alters carbon flow through the hepatic folate-dependent one-carbon pool in rats. Carcinogenesis 17: 1695-1700.

University of Wisconsin – Postdoctoral Fellow (1992 – 1997) Eisenstein, R.S., Tuazon, P.T., Schalinske, K.L., Anderson, S.A. & Traugh, J.A. (1993) Iron-

responsive element-binding protein. Phosphorylation by protein kinase C. J. Biol. Chem. 268: 27363-27370.

Schalinske, K.L. & Eisenstein, R.S. (1996) Phosphorylation and activation of both iron regulatory proteins 1 and 2 in HL-60 cells. J. Biol. Chem. 271: 7168-7176.

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Chen, O.S., Schalinske, K.L. & Eisenstein, R.S. (1997) Dietary iron intake modulates the activity of iron regulatory proteins (IRPs) and the abundance of ferritin and mitochondrial aconitase in rat liver. J. Nutr. 127: 238-248.

Schalinske, K.L., Anderson, S.A., Chen, S-H., Tuazon, P.T., Traugh, J.A. & Eisenstein, R.S. (1997) The iron sulfur cluster of iron regulatory protein 1 modulates accessibility of RNA binding and phosphorylation sites. Biochemistry 36: 3950-3958.

Schalinske, K.L., Blemings, K.P., Steffen, D.W., Chen, O.S. & Eisenstein, R.S. (1997) Iron regulatory protein 1 is not required for the modulation of iron homeostasis in a murine pro-B lymphocyte cell line. Proc. Natl. Acad. Sci. U.S.A. 94: 10681-10686.

Schalinske, K.L., Chen, O.S. & Eisenstein, R.S. (1998) Iron differentially stimulates translation of mitochondrial aconitase and ferritin mRNAs in mammalian cells. Implications for iron regulatory proteins as regulators of mitochondrial citrate utilization. J. Biol. Chem. 273: 3740-3746.

Chen, O.S., Blemings, K.P., Schalinske, K.L. & Eisenstein, R.S. (1998) Dietary iron intake rapidly influences iron regulatory proteins, ferritin subunits and mitochondrial aconitase in rat liver. J. Nutr. 128: 525-535.

Iowa State University – Assistant/ Associate/ Professor (1999 – present) Rowling, M.J. & Schalinske, K.L. (2001) Retinoid compounds activate and induce hepatic

glycine N-methyltransferase in rats. J. Nutr. 131: 1914-1917. Rowling, M.J., McMullen, M.H. & Schalinske, K.L. (2002) Vitamin A and its derivatives

induce hepatic glycine N-methyltransferase and hypomethylation of DNA in rats. J. Nutr. 132: 365-369.

McMullen, M.H., Rowling, M.J., Ozias, M.K. & Schalinske, K.L. (2002) Activation and induction of glycine N-methyltransferase by retinoids are tissue- and gender-specific. Arch. Biochem. Biophys. 401: 73-80.

Rowling, M.J., McMullen, M.H., Chipman, D.C. & Schalinske, K.L. (2002) Hepatic glycine N-methyltransferase is up-regulated by methionine in rats. J. Nutr. 132: 2545-2549.

Schalinske, K.L. (2003) Interrelationship between diabetes and homocysteine metabolism: hormonal regulation of cystathionine β-synthase. Nutr. Rev. 61: 136-138.

Rowling, M.J. & Schalinske, K.L. (2003) Retinoic acid and glucocorticoid treatment induces hepatic glycine N-methyltransferase and lowers plasma homocysteine concentrations in the rat and rat hepatoma cells. J. Nutr. 133: 3392-3398.

Ozias, M.K. & Schalinske, K.L. (2003) All-trans-retinoic acid rapidly induces glycine N-methyltransferase in a dose-dependent manner and reduces circulating methionine and homocysteine levels in rats. J. Nutr. 133: 4090-4094.

Tanghe, K.A., Garrow, T.A. & Schalinske, K.L. (2004) Triiodothyronine treatment attenuates the induction of hepatic glycine N-methyltransferase by retinoic acid and elevates plasma homocysteine concentrations in rats. J. Nutr. 134: 2913-2918.

Nieman, K.M., Rowling, M.J., Garrow, T.A. & Schalinske, K.L. (2004) Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid. J. Biol. Chem. 279: 45708-45712.

Schalinske, K.L. & Nieman, K.M. (2005) Disruption of methyl group metabolism by ethanol. Nutr. Rev.63: 387-391.

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Nieman, K.M., Hartz, C.S., Szegedi, S.S., Garrow, T.A., Sparks, J.D. & Schalinske, K.L. (2006) Folate status modulates the induction of hepatic glycine N-methyltransferase and homocysteine metabolism in diabetic rats. Am. J. Physiol. Endocrinol. Metab. 291: E1235-E1242.

Hanson, L.N., Engelman, H.M., Alekel, D.L., Schalinske, K.L., Kohut, M.L. & Reddy, M.B. (2006) Effects of soy isoflavones and phytate on homocysteine, C-reactive protein, and iron status in postmenopausal women. Am. J. Clin. Nutr. 84: 774-780.

Hartz, C.S., Nieman, K.M., Jacobs, R.L., Vance, D.E. & Schalinske, K.L. (2006) Hepatic phosphatidylethanolamine N-methyltransferase expression is increased in diabetic rats. J. Nutr 136: 3005-3009.

Hartz, C.S. & Schalinske, K.L. (2006) Phosphatidylethanolamine N-methyltransferase and regulation of homocysteine metabolism. Nutr. Rev. 64: 465-467.

Williams, K.T. & Schalinske, K.L (2007) New insights into the regulation of methyl group and homocysteine metabolism. J. Nutr 137: 311-314 (invited review).

Schroeder, S.E., Reddy, M.B. & Schalinske, K.L. (2007) Retinoic acid modulates hepatic iron homeostasis in rats by attenuating the RNA-binding activity of iron regulatory proteins. J. Nutr., 137: 2686-2690.

Williams, K.T., Garrow, T.A. & Schalinske, K.L. (2008) Type 1 diabetes leads to tissue-specific DNA hypomethylation in male rats. J. Nutr. 138: 2064-2069.

Strakova, J., Williams, K.T., Gupta, S., Schalinske, K.L., Kruger, W.D., Rozen, R., Jiracek, J., Lucas, L. & Garrow, T.A. (2010) Dietary intake of S-(α-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats. Nutr. Res. 30: 492-500.

Schalinske, K.L. & Williams, K.T. (2010) Homocysteine metabolism: its regulation and implications in health and disease. BioFactors 36: 19-24 (invited review).

Nieman, K.M. & Schalinske, K.L. (2011) Insulin abrogates perturbation of methyl group and homocysteine metabolism in diabetic rats. Am. J. Physiol. Endocrinol. Metab. 301: E560-E565.

Williams, K.T. & Schalinske, K.L. (2012) Tissue-specific alterations of methyl group metabolism and DNA hypermethylation in the Zucker (type 2) diabetic fatty (ZDF) rat. Diabetes Metab. Res. Rev. 28: 123-131.

Schalinske, K.L. & Smazal, A.L. (2012) Homocysteine imbalance – a pathological metabolic marker. Adv. Nutr. 3: 755-762 (invited review).

Smazal, A.L., Borcherding, N.C., Anderegg, A.S., Schalinske, K.L., Whitley, E.M. & Rowling, M.J. (2013) Dietary resistant starch prevents urinary excretion of 25-hydroxycholecalciferol and vitamin D-binding protein in type 1 diabetic rats. J. Nutr. 143: 1123-1128.

Neuman, J.C., Albright, K.A. & Schalinske, K.L. (2013) Exercise prevents hyperhomocysteinemia in a dietary folate-restricted mouse model. Nutr. Res., 33: 487-493.

Choi, S-W., Claycombe, K.J., Martinez, J.A., Friso, S. & Schalinske, K.L. (2013) Nutritional epigenomics: a portal to disease prevention. Adv. Nutr. 4: 530-532.

Birt, D.F., Boylston, T., Hendrich, S., Jane, J-L., Hollis, J., Li, L., McClelland, J., Moore, S., Phillips, G., Rowling, M.J., Schalinske, K.L. & Whitely, E. (2013) Digestion resistant starch, promise for improving health. Adv. Nutr. 4: in press.

Martinez, J.A., Melagro, F.I., Claycombe, K.J. & Schalinske, K.L. (2013) Epigenetics in adipose tissue, obesity, weight loss, and diabetes. Adv. Nutr. 4: in presss.

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Nonnecke, E.B., Knoblock, V.E., Rowling, M.J., Paige, K.N. & Schalinske, K.L. (2013) Induction of the tumor susceptibility gene glycine N-methyltransferase by all-trans-retinoic acid and dexamethasone. Nutr. Cancer., under review.

Neuman, J.C., Boddicker, R.L. & Schalinske, K.L. (2013) Egg protein stimulates hepatic homocysteine remethylation in rats. J. Nutr , to be submitted.

Nonnecke, B.J. & Schalinske, K.L. (2013) Creatine and genistein supplementation attenuates folate-deficiency-induced hyperhomocysteinemia. J. Nutr. Metab., to be submitted

Williams, K.T. & Schalinske, K.L. (2013) Chronic retinoic acid administration persistently disrupts hepatic methyl group metabolism. Hepatology., to be submitted.

BOOK CHAPTERS Schalinske, K.L. (2008) Hepatic sulfur amino acid metabolism. In: Glutathione and sulfur

amino acids in human health and disease (Masella, R. & Mazza, G., eds.), Wiley, pp. 73-90 (invited chapter).

OTHER MATERIALS Conn, C.A., Schalinske, K.L. & Jacob, M. (2008) A Test Bank/ Study Guide in: Advanced

Nutrition and Human Metabolism, 5th ed (Gropper, S.S., Smith, J.L. & Groff, J.L.), Wadsworth.

Schalinske, K.L. (2008) Study Guide for: Advanced Nutrition and Human Metabolism, 5th ed (Gropper, S.S., Smith, J.L. & Groff, J.L.), Wadsworth.

Schalinske, K.L. (2010) High quality proteins can impact circulating homocysteine levels. Nutrition Close-Up 27: 4-5 (Egg Nutrition Center publication).

Schalinske, K.L. (2012) Study Guide for: Advanced Nutrition and Human Metabolism, 6th ed (Gropper, S.S., Smith, J.L. & Groff, J.L.), Wadsworth.

MANUSCRIPTS IN PREPARATION Chipman, D.C., Knoblock, V.E. & Schalinske, K.L. Retinoyl β-glucuronide does not increase

hepatic glycine N-methyltransferase in male Sprague Dawley rats. Knoblock, V.E. & Schalinske, K.L. Folate status attenuates the perturbation of methyl group

metabolism by retinoic acid. Knoblock, V.K., Schroeder, S.E. & Schalinske, K.L. Age increases the sensitivity of rats to

retinoid-mediated alterations in methyl group metabolism. Nieman, K.M.& Schalinske, K.L. Soy protein and supplemental cysteine attenuates retinoid-

mediated perturbation of methyl group metabolism in rats. Neuman, J.C., Nieman, K.M., McGuire, A. & Schalinske, K.L. Aberrant methyl group and

homocysteine metabolism in the non-obese diabetic mouse. Smazal, A.L. & Schalinske, K.L. Retinoic acid administration lowers brain serotonin levels in

rats.

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ABSTRACTS/ PRESENTATIONS Bremer, J., Woldegiorgis, G., Schalinske, K. & Shrago, E. (1984) Malonyl CoA inhibition of

carnitine palmitoyl transferase (CPT) in Triton X-100 extracts and residues of rat liver mitochondria (RLM). Fed. Proc. 43: 2040.

Strieleman, P.J., Schalinske, K.L. & Shrago, E. (1985) Incorporation of the purified brown adipose tissue mitochondria uncoupling protein into liposomes using octyl glucoside. Fed. Proc. 44: 1161.

Keim, N.L., Francis, A.M., Voss, S.G., Schalinske, K.L. & Woldegiorgis, G. (1985) Hepatic intermediary fat metabolism during total parental nutrition (TPN). Fed. Proc. 44: 1153.

Strieleman, P.J., Schalinske, K.L., Henningfield, M.F. & Shrago, E. (1985) Regulation of the reconstituted brown adipose tissue mitochondria uncoupling protein. XIII International Congress of Nutrition meeting.

Schalinske, K.L., Handley, J.K. & Steele, R.D. (1987) Effect of retinoids on methionine (MET) metabolism in rats. Fed. Proc. 46: 573.

Schalinske, K.L. & Steele, R.D. (1988) The effect of 13-cis-retinoic acid (CRA) on methionine (MET) metabolism in rats. FASEB J. 2: A1765.

Schalinske, K.L. & Steele, R.D. (1989) Quantitation of hepatic folate-dependent one-carbon (1-C) metabolism in the rat. FASEB J. 3: A266.

Schalinske, K.L. & Steele, R.D. (1990) The use of in vivo tracer kinetic techniques in the quantification of folate-dependent one-carbon metabolism. FASEB J. 4: A919.

Schalinske, K.L. & Steele, R.D. (1991) In vivo quantification of folate-dependent one-carbon (1-C) metabolism. FASEB J. 5: A914.

Schalinske, K.L. & Steele, R.D. (1992) The effect of methotrexate on carbon flux through the folate-dependent one-carbon (1-C) pool. FASEB J. 6: A1499.

Eisenstein, R.S., Tuazon, P., Schalinske, K., Anderson, S.A. & Traugh, J.A. (1992) Protein kinase C-dependent phosphorylation of the iron responsive element binding protein (IRE-BP). In: Translational Control 1992, p. 83, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

Eisenstein, R.S., Tuazon, P.T., Schalinske, K., Anderson, S.A. & Traugh, J.A. (1993) Phosphorylation of the iron responsive element binding protein (IRE-BP) by protein kinase C. FASEB J. 7: A297.

Schalinske, K.L., Tuazon, P.T., Anderson, S.A., Traugh, J.A. & Eisenstein, R.S. (1993) Activation of protein kinase C stimulates phosphorylation of the iron responsive element binding protein (IRE-BP) in vitro and in intact cells. FASEB J. 7: A1081.

Schalinske, K.L. & Eisenstein, R.S. (1994) Phosphorylation and activation of the iron responsive element binding protein (IRE-BP) in HL 60 cells. FASEB J. 8: A921.

Schalinske, K.L., Tuazon, P.T., Traugh, J.A. & Eisenstein, R.S. (1994) Phosphorylation is associated with activation of RNA binding by iron responsive protein (IRP). In: Translational Control 1994, Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.

Schalinske, K.L., Simmons, B., Anderson, S.A. & Eisenstein, R.S. (1995) Structural differences in iron regulatory protein (IRP) alters RNA binding characteristics and phosphorylation potential. FASEB J. 9: A982.

Chen, S., Ta, S., Schalinske, K.L. & Eisenstein, R.S. (1995) Effects of dietary iron intake on rat liver iron-regulatory protein (IRP). FASEB J. 9: A982.

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Eisenstein, R.S., Anderson, S.A., Simmons, B. & Schalinske, K.L. (1995) Phosphorylation of iron responsive protein (IRP) is associated with activation of RNA binding in HL 60 cells and apo-IRP is the preferred substrate for phosphorylation. International Conference on Bioiron (ICBI).

Schalinske, K.L. & Eisenstein, R.S. (1996) Cell-type specific redox regulation of iron regulatory protein (IRP) 1 and IRP2. 1996 RNA Meeting, Madison, WI.

Chen, S., Schalinske, K.L. & Eisenstein, R.S. (1996) Decreased mitochondrial aconitase activity and abundance in iron deficiency suggests a role for iron regulatory proteins in modulating energy metabolism. 1996 RNA Meeting, Madison, WI.

Chen, O.S., Schalinske, K.L. & Eisenstein, R.S. (1997) Modulation of mitochondrial aconitase by dietary iron implicates iron regulatory proteins (IRPs) as regulators of TCA cycle function and citrate metabolism. FASEB J. 11: A444.

Rowling, M.J. & Schalinske, K.L. (2001) Glycine N-methyltransferase is up-regulated by all-trans- and 13-cis-retinoic acid in rats. FASEB J. 15: A602.

Rowling, M.J. & Schalinske, K.L. (2001) Retinoid compounds activate and induce hepatic glycine N-methyltransferase in rats. James Allen Olson Memorial Symposium, Functions and Actions of Retinoids and Carotenoids: Building on the Vision of James Allen Olson, Iowa State University, Ames, IA.

McMullen, M.H., Rowling, M.J. & Schalinske, K.L. (2001) Tissue-specific activation and induction of glycine N-methyltransferase by vitamin A and its derivatives. James Allen Olson Memorial Symposium. Functions and Actions of Retinoids and Carotenoids: Building on the Vision of James Allen Olson, Iowa State University, Ames, IA.

Reddy, M.B., Guizhen, Z., Schalinske, K. & Tanumihardjo, S. (2002) Effect of retinol and carotenoid analogs on nonheme iron bioavailability in Caco-2 cells. FASEB J. 16: A271.

Rowling, M.J., McMullen, M.H. & Schalinske, K.L. (2002) Vitamin A and its derivatives active hepatic glycine N-methyltransferase and induce hypomethylation of DNA in rats. FASEB J. 16: A744.

McMullen, M.H., Rowling, M.J., Ozias, M.K. & Schalinske, K.L. (2002) Activation and induction of glycine N-methyltransferase by retinoids is tissue- and gender-specific. FASEB J. 16: A744.

Knoblock, V., Schroeder, S.E. & Schalinske, K.L. (2003) Perturbation of methyl group, homocysteine, and lipid metabolism by retinoids: effect of age. FASEB J. 17: A309.

Nieman, K., Ozias, M.K. & Schalinske, K.L. (2003) Role of dietary protein level and type to modulate retinoid-mediated perturbation of methyl group metabolism. FASEB J. 17: A309.

Ozias, M.K. & Schalinske, K.L. (2003) Dose-dependent induction of glycine N-methyltransferase (GNMT) by retinoid administration. FASEB J. 17: A309.

Rowling, M.J. & Schalinske, K.L. (2003) Gluconeogenic modulation of retinoid-mediated perturbation of methyl group metabolism. FASEB J. 17: A310.

Clark, L.N., Barwick, H.M., Alekel, D.L., Schalinske, K.L. & Reddy, M.B. (2004) Cardiovascular disease risk factors in postmenopausal women. FASEB J. 18: A133.

Knoblock, V.E. & Schalinske, K.L. (2004) Folate status attenuates the perturbation of methyl group metabolism by retinoic acid. FASEB J. 18: A173.

Nieman, K.M., Rowling, M.J. & Schalinske, K.L. (2004) Perturbation of methyl group metabolism by diabetes and retinoid compounds. FASEB J. 18: A174.

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Tanghe, K.A. & Schalinske, K.L. (2004) Hyperthyroidism attenuates retinoic acid-mediated alterations of methyl group metabolism, whereas retinoic acid treatment prevents triiodothyronine-induced hyperhomocysteinemia in rats. FASEB J. 18: A174.

Hartz, C.A. & Schalinske, K.L. (2005) Diabetes increases the activity of hepatic phosphatidylethanolamine N-methyltransferase. FASEB J. 19: A51.

Nieman, K.M. & Schalinske, K.L. (2005) Folate status modulates the induction of hepatic glycine N-methyltransferase, whereas hyperhomocysteinemia due to folate deficiency was attenuated in diabetic rats. FASEB J. 19: A50.

Schroeder, S.E. & Schalinske, K.L. (2005) Retinoic acid decreases the RNA binding activity of hepatic iron regulatory proteins. FASEB J. 19: A1500.

Tanghe, K.A.& Schalinske, K.L. (2005) Sustained induction of hepatic glycine N-methyltransferase expression in rats during chronic administration of all-trans-retinoic acid. FASEB J. 19: A1500.

Hartz, C.S. & Schalinske, K.L. (2006) Diabetes upregulates phospholipid methylation. FASEB J. 20: A859.

Nieman, K.M. & Schalinske, K.L. (2006) Modulation of methyl group and homocysteine metabolism by insulin treatment in diabetic rats. FASEB J. 20: A607.

Schroeder, S.E. & Schalinske, K.L. (2006) Interaction between vitamin A status and iron homeostasis is mediated by iron regulatory proteins. FASEB J. 20: A1315.

Williams, K.T. & Schalinske, K.L. (2006) Hepatic and renal metabolism of methyl groups and homocysteine are altered by diabetes and glucocorticoid treatment in rats. FASEB J. 20: A607.

Straková, J, Sandy, S., Williams, K., Schalinske, K.L. & Garrow, T.A. (2006) Inhibition of betaine-homocysteine S-methyltransferase (BHMT) increases plasma total homocysteine (tHcy) in mice. FASEB J. 20: A609.

Batres-Marquez, S., Carriquiry, A., Jensen, H.H. & Schalinske, K.L. (2007) Choline in the diets of the US population: NHANES, 2003-2004. FASEB J. 21: lb219..

Nieman, K.M. & Schalinske, K.L. (2007) Vitamin D treatment modulates methyl group metabolism in diabetic rats. FASEB J. 21: 226.2.

Nonnecke, E.B. & Schalinske, K.L. (2007) Creatine supplementation exacerbates hyperhomocysteinemia in folate-restricted rats. FASEB J. 21: 545.5.

Strakova, J., Kruger, W., Rozen, R., Schalinske, K. & Garrow, T. (2007) Role of betaine-homocysteine S-methyltransferase in homocysteine remethylation. Clin. Chem. Lab. Med. 45: A27.

Williams, K.T. & Schalinske, K.L. (2007) Diabetes results in altered epigenetic regulation of gene expression. FASEB J. 21: 241.3.

Luchtel, R., Garrow, T.A. & Schalinske, K.L. (2008) Egg white protein prevents hyperhomocysteinemia in folate-deficient rats. FASEB J. 22: 894.5.

Nieman, K.M., McGuire, A., & Schalinske, K.L. (2008) Methyl group metabolism in maternal and fetal hepatic tissues is altered by diabetes and retinoic acid treatment. FASEB J. 22: 894.8.

Nonnecke, E.B., Weisenhorn, T. & Schalinske, K.L. (2008) Phosphocreatine and genistein supplementation attenuate plasma homocysteine concentrations in rats. FASEB J. 22: 894.6.

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Williams, K.T. & Schalinske, K.L. (2008) Tissue-specific regulation of glycine N-methyltransferase (GNMT) activity and abundance in the prediabetic ZDF (type 2) rat: evidence for two regulated GNMT isoforms. FASEB J. 22: 894.7.

Nieman, K.M., McGuire, A.S., & Schalinske, K.L. (2009) Characterization of homocysteine and methyl group metabolism in female non-obese diabetic (NOD) mice. FASEB J. 23: 557.5.

Nonnecke, E.B. & Schalinske, K.L. (2009) Genistein reduces plasma homocysteine concentrations in a folate deficient rat model. FASEB J. 23: 557.6.

Schalinske, K.L., Luchtel, R.A. & Garrow, T.A. (2009) Folate-independent remethylation of homocysteine is increased by dietary egg white protein. FASEB J. 23: 335.2.

Williams, K.T. & Schalinske, K.L. (2009) Abnormal methyl group metabolism and epigenetic regulation in the Zucker (type 2) diabetic fatty rat. FASEB J. 23: 555.6.

Neuman, J.C., Nieman, K.M. & Schalinske, K.L. (2010) Characterization of methyl group metabolism in the non-obese diabetic (NOD) mouse. FASEB J. 24: 915.11.

Nonnecke, E.B. & Schalinske, K.L. (2010) Genistein mediates perturbations in one-carbon metabolism during diet-induced folate deficiency. FASEB J. 24: 915.10.

Williams, K.T. & Schalinske, K.L. (2010) Aberrations of methyl group and homocysteine metabolism during progression of diabetes in the ZDF rat. FASEB J. 24: 228.4.

Neuman, J.C., Albright, K., & Schalinske, K.L. (2011) Exercise prevents hyperhomocysteinemia in a folate-restricted mouse model. FASEB J. 25: 597.2.

Schalinske, K.L., Smazal, A., Smith, E.A. & Small, M. (2012) Dietary resistant starch attenuates perturbations in carbohydrate and methyl group metabolism in type 1 diabetic rats. FASEB J. 26: (in press).

Stearns JE, Helms TH, Cray NL, Pillatzki A, Birt DF, Schalinske K, Whitley EM. The influence of dietary resistant starch on the neuroplasticity of 5-HT receptor neurons in the myenteric plexus. NIH-Merial Symposium, Ft. Collins, CO, August 5, 2012, and ISU CVM Summer Scholars Research Day, Iowa State University, August 10, 2012.

Helms TH, Stearns JE, Cray NL, Pillatzki A, Birt DF, Schalinske K, Whitley EM. Influence of a Resistant Starch Diet on Lamina proprial lymphocyte expression. NIH-Merial Symposium, Ft. Collins, CO, August 5, 2012, and ISU CVM Summer Scholars Research Day, Iowa State University, August 10, 2012.

Smazal, A.L. & Schalinske, K.L. (2013) Retinoic acid lowers brain serotonin concentrations in rats. FASEB J. 27: (in press).

Anderegg, A. & Schalinske, K.L. (2013) Impact of resistant starch to attenuate type 1 diabetes in the non-obese diabetic mouse. FASEB J. 27: (in press).

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