04 review literature

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Review of Literature Review of Literature Review of the drug I. Vedic Period 1 Reference regarding the plant Langali is available in Atharva Veda. In dwiteeya khanda it is told as Halaavayva and does the shamana of various rogas. It is mentioned as Vrishabha sirayukta and nivartaka of Peedayukta roga Again in thriteeya khanda its mentioned to be Paviravat that is does vipatana of Bhoomi, then it is said to be Sushimam having Karshana property and also referred as Somasatasaru. II. Samhita period Charaka Samhita: 2 Acharya Charaka classified Langali under the Bhedaneeya gana and has included it under moolaja visha. He also quotes use of Langali moola to induce Sukaprasava in Jatisootra adhyaaya of shareerasthana 2 . Further in chikitsasthana there is reference regarding Langali moola in Kushtachikitsaadhyaaya for vataja and kaphaj kushta 2 . Pharmacognostic and Phytochemical study of langali (gloriosa superba linn) w.s.r.t its shodhana“ 5

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Page 1: 04 Review Literature

Review of Literature

Review of Literature

Review of the drug

I. Vedic Period1

Reference regarding the plant Langali is available in Atharva Veda. In dwiteeya

khanda it is told as Halaavayva and does the shamana of various rogas. It is

mentioned as Vrishabha sirayukta and nivartaka of Peedayukta roga

Again in thriteeya khanda its mentioned to be Paviravat that is does vipatana of

Bhoomi, then it is said to be Sushimam having Karshana property and also referred as

Somasatasaru.

II. Samhita period

Charaka Samhita:2

Acharya Charaka classified Langali under the Bhedaneeya gana and has included

it under moolaja visha. He also quotes use of Langali moola to induce Sukaprasava

in Jatisootra adhyaaya of shareerasthana2.

Further in chikitsasthana there is reference regarding Langali moola in

Kushtachikitsaadhyaaya for vataja and kaphaj kushta2.

Sushrutha Samhita:3

Acharya Shusrutha classifies it under the “Pippalyadigana” and in

kaphsamshaman dravyas. He quotes its use in preparation of kshara. The application

of moola is told in case of Garbhasanga and for Aparapatana. He also mentions

Langali for Vrana shodhana and Bhagandhara shodhana.3

Sushrutha also mentions Langali in treatment of Kustha and Kaphaja arbuda He

also mentions Langali as a ingredient in oil which is told to best in Unmanth

Paste of its moola is indicated for Ajagallika.It also mentioned in “Vatashonita

chikitsa”

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In uttaratantra he quotes the use of Langali moola in case of Gulma, Hridroga

and Shwasa.3

Ashtanga Sangraha4

Sangrahakara have grouped it under Arkadi gana naming it as ‘Vishalya’. He

quotes its properties as Laghu, Sara, Ruksha and Tikta. In Case of aparasangh he

prescribes this moola to be applied to the sole and palm. It also quoted in case of arsha

and for vrana Shodhana.4

Ashtanga Hridhaya:5

Vagabhat classify Langali under Arkadi gana referring it as “Vishalya”. He tells

the use of moola in case of “Teekshna kshara”

In case of grabha sang Vagabhat tells to fumigate the vagina with “Langalika”.

He also mentions its use in Arsha, Udara and Kushta. It is specially mentioned in case

of sarvadoshaja Vatarakta for internal use.

The nasya of oil prepared from Langali and Suras is told in case of Indralupta. Its

oil is also indicated in Vrana shodhana and Bhagandhara shodhana. Abhyanjana of oil

prepared out of Langali moola is indicated in case of Granti, Arbuda and Pama. It is

also told “Sarpavishapratisheda”.

In uttaratantra Vagabhat specially mentions about “Rasayana” effect of Langali

Bhela Samhita:6

Bhela has mentioned Langali in ‘Kustha Chikitsa’ told to use it with Karir, Danti,

and Dravanti for bahirparimarjana.

Chakradutta:7

Chakrapani mentions “Sukaprasava yoga” of Langali moola with other herbs. He

also mention about use of Langali in Nashtashalya prayoga and in vranashotha.

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Yogaratnakar:8

It is mentioned under the “Upavisha Varga”. Its shodhana has been mentioned.

Further he mentions its use in Krimi, Bhagandhara, Kushta, Kshudraroga, and

Krimikarna and in Visha.

Shrangdhara samhita:9

Mentioned under Upavisha Varga. Sharangdhara mentions it in case of

Gandamala, Kilas and Kushta

III. NIGHUNTU PERIOD:

In nighantu we get references regarding Langali

Bhavaprakash Nighantu:10

It is mentioned under Upavisha Varga and mentioned about 8 synonyms like

Agnishikha, Garbhapatani, Halini, etc. and mentioned its two types as Stree, Purusha.

Gunakarma as Ushna Katu ,Deepaka,Balyaand Vamaka.10

Raja Nighantu:11

Mentioned synonyms like Gunakarma mentioned as Sarak, Bastishoolahara,

Krimighna, Shophahara11.

Dhanwantari Nighantu:12

It is mentioned under “Upavisha Varga”. Synonyms: Agnimukhi, Deepta,

Halini, Kalikari, Vishalya, Nakta. Gunakarma; Ushna, tikta, katu & indicated in

Apachi, Vrana shodhana. Sarak, Shalya nirharana.

In this nighantu, the synonyms of Jalapippali and Narikela are mentioned as

‘langali’.12

Shodala Nighantu:13

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Acharya Shodala classifies Langali in the “karviradi Varga”. He has further

mentions its synonyms as Agnijihwa, Swarapushpika and Shikhimukhi. Shodala

indicates this drug for Krimi, Kushta and for Vrana shodhana.13

Kaiyadev Nighantu:14

He classified Langali under the “Varga”.

Synonyms; Vanhijihwa, Vanhimukha, Prabhata. Gunakarma :kustha , Shalya

nirharana, Krimi, Shopha, and Vishahara14.

Shaligram Nighantu:15

Its synonyms have been mentioned as Kalikari, Deepta, Agnijiwha, Vanhishikha,

Vanhivaktra, languli.

He classifies it under guduchyadi varg and mentions its use for Kushta,

Dushtavrana.15

Priya Nighantu:16

Author of this nighantu classifies this under Shatpushadi varg. He has added

synonyms like Prokta, Vanhipushpa.

And he mentions its qualities as Pittala, Garbhapatini and Krimighi.16

SYNONYMS:

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In Samhithas, Nighantus, several synonyms are used for denoting a drug. Naming

of a drug is based on the popular name, nature, available place, resemblance, veerya

etc.

Table No 1:

SlNo. Synonyms CS S.S A.H B.P K.N D.N S.N N.R M.N H.N N.

A

1. Langali + + + + + + + + + + +

2. Agnimukha + + +

3. Agnishikha + +

4. Agnijihwa +

5. Ananta +

6. Dipta + +

7. Garbhanuta + +

8. Garbhapatani + + + + + +

9. Halini + + + + + +

10. Haripriya

11. Indupushpika + + + + +

12. Kalikari + + + + + +

13. Kandali

14. Langalika + + + +

15. Languli +

16. Prabhata +

17. Pramatta +

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18. Pushpasurabha + + +

19. Nakta +

20. Shakrapusphi + + +

21 Shikhimukhi +

22. Swarnapushpi

ka

+

23. Vanhivaktra + + +

24. Vishalya + + + + + + +

25. Vanjihwa +

26. Vanhimukhi +

27. Vranaharita +

28. Shiri + + +

Meaning of Synonyms :17

Langali : It is looks like plough

Agnimukha: Flowers are red colour and resemble fire.

Agnishikha: Flowers are red colour and resemble fire

Garbhapatani: It induces abortion.

Garbhanuta: It destroys Garbha.

Deepta : It stimulates digestive fire ( Agni deepana).

Halini: It resemble Plough.

Haripriya: It is liked by Lord Vishu.

Kalikari: It is belived, that it creats quarells.

Vishalya: It is used remove shalya(foriegn matter) from the body.

Pushpasaurabha; Have beautiful flowers.

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Swarpushpika : Flowers are golden coloured initially then change to red colour.

Vranaharita: It used to treat Dushta –vrana.

GUNA KARMA OF LANGALI

In nighantus the guna of Langali is mentioned as Ushna and Teekshna. On the

same lines the is told as Tikta, Katu but only in Bhavaprakash nighantu and

Harityakyadi nighantu kashaya rasa is added to the previous. Vipaka of langali is told

as Katu only in Bhavaprakash nighantu and Kaiyadeva nigahantu.Its virya is Ushna

and Doshghnata is Kaphavatahara.

KARMA:

In Brihatrayee and Laghutrayee langali is well known for its Garbhapatana effect.

1. Garbhapatana(C.S)

2. Aparapatana(S. S)

3. Kushta (S.S)

4. Krimi(B.P)

5. Vrana shodhana(S.S)

6. Bastishoola (K.N)

7. Karna roga( A.H)

8. Indralupta(A.H)

9. Unmathana(S.S)

10. Shalya nirhana(D.N)

11. Vishahara(A.H)

12. Rasayana (A.H)

13. Apachi (S.

14. Granti(S.S)

15. Vatarakta(V.S)

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16. Gandamala(A.S)

17. Shopha(B.P)

18. Arsha(H.N)

DIFFERENT FORMULATIONS OF LANGALI

IN DIFFERENT AYURVEDIC TEXTS

1.Langali Rasayana (A.H.U)

2. Sukhaprasava yoga (C.D)

3. Nirgundi Tail (Y.R)

4.Kriminashaka Dhoopa (Y.R)

5.Nishadi Tail (Y.R)

6.Vishyandhana Tail (Y.R)

7.Gunjadi Udwartana (Y.R)

8.Krimikarna Yoga (Y.R)

9.Langali Nasya (Y.R)

10. Kasisadhya Tail (S.S)

11. Langali Tail (S.S)

12.Kankasindhura rasa (S.S)

13. Vishagarbha Tail (Y.R)

14. Langalyadi Gutika (G.N)18

15. Langalyadi Vatika (G.N)18

MYTHOLOGICAL REVIEW:19

In Valmiki Ramayana reference regarding langali is obtained. It is mentioned as

Sanjivini, Vishalya, Mahoshadhi and refered as Suvarnakarani

TAXONOMICAL CLASSIFITION OF LANGALI20

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Kingdom: : Plantae

Sub Kingdom : Tracheobiophyta

Division : Magnoliophyta

Sub- Division : Angiospermae

Class : Monocotyledon

Sub-class : Liliidae

Order : liliales

Family : Liliaceae

Sub-family : Wurmbeodideae

Genus : Gloriosa

Species : superba

Botanical Name : Gloriosa superba Linn.

VERNACULAR NAMES21

English: Glory lily

Hindi: Kalihari, Kalikari, Kathari, Kulhari, Langali

Bengali: Bisha, Bishalanguli, Ulatchandal.

Gujarathi: Shingdiovachanaga

Kannada: Kolikutuma

Malayalam: Kantal, Malattamara.

Marathi: Karianag, Nagkaria, Indai.

Punjabi: Mulim, Kariari.

Tamil: Akkinichilam, Anaravam, Illangali, Irumbu, Kodai , Tondari.

Telugu: Adavinabbhi, Agnisikha, Kalapagadda, Langali, Pottidumpa.

Tulu: Balipapu, Kenakannadapu.

Simhaleese: Neyaangalla, Niyangalla.

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Burmese: Simadon, Hseemeetouk.

Canarease: Agmisikhe, Akkatangaballi, Huliyuguru, Nangulika, Kolikutuma.

Java: Akarsoengsang.

Oriya: Garbhhoghhatotono, Ognisikha, Panjangulia, Meheriaphhulo.

Urdu : Kulhar, Kanol.

Lushkar : Husangibdo, merkam-par

Kano: Gudumarzomo

Deccan: Naktabachhnag.

CONTROVERSIAL ASPECTS OF LANGALI:22

Vaidya Bapalalji claims it to be non-poisonous. He quotes that Vagabhat in

‘Astang Hrdaya’ has it as Rasayan so it should not be considered as Upavisha. The

word Languli which synonym, may be confused with Langali. Even in Amarkosh, he

gives synonym for Jalapippali as Langali. Charaka, Sushruta, and Vagabhata have

not mentioned the term Langali, latter writers like Bhavaprakash gave it.

DESCRIPTION OF GENUS23

Gloriosa Linn:

Habitat: Climbing herbs

Stem: Leafy, springing from a naked tuberous rootstocks.

Leaves: Alternate, Opposite or 3- natelywhorled, lanceolate, strongly nerved with a

long spiral tendril like apex.

Flowers: Large, showy, axillary, solitary, pedicels reflexed at tip

Perianth: Petaliod, persistent.

Stamens: 6-Subequalspreading or reflexed, the margins often undulate, hypogynous,

Filaments-filiform, anther-linear, dorsi-flexed, versatile, dehiscing.

Gynaceium:Ovary-3-celled, Ovules-numerous in each cell

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Style-Filliform, deflexed with three subulet arms and stigmatous within.

Fruit: Large, coriaceious, septicidal capsule.

Seeds: Sub-globose: Testa spongy, wing like, embryo-cylindrical.

Species-08 24

01) G.superba. Linn

02) G.acuminatum Muell.Arg.

03) G. arborescens. Blume

04) G. hohenackeri. Bedd

05) G.littorale. Blume

06) G. neilgherrense. Wight

07) G. vcelutinum .Wight

08) G. zeylanicum. Juss

MORPHOLOGY25

An herbaceous tall glabrous branching climber

ROOT STOCK: Arched, solid, fleshy white, cylindrical tuber, 15-30cm (length) X

2.5-3.8 cm (diameter), tapering at both the end, bifurcatlly branched forming ‘V’

shape, roots fibrous.

STEM: Annual 3-6 mts long, herbaceous, given off from the young tubers.

LEAVES:

Sessile or nearly so, 7.5cm to15cm X 2 to 4.5 cm, scattered or opposite or

sometimes arises from the separation of the internodes, teranately whorled, ovate/

lanceolate, acuminate tip ending in a tendril like spiral, base cordate, nerves parallel.

FLOWERS:

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Large axillary, solitary or subcorymbose towards the end of the branches from

the nearness of the leaves, remain about 7 days without withering,

Pediciles-7.5-15 cm long, the tip is deflexed.

Perianth- 6.3cmX8-13cm long, linear lanceolate.with crispy waved margins at

first, then turn yellow passing through orange and scarlet to crimson red.

Filament: 3.8-4.5cm long, anthers/spreading 13mm long, style-5cm long, and

arms about 6mm long.

FRUIT:

Capsule about 2X4.5 cm, linear oblong, three celled.

SEED:

Sub-globose: Testa spongy, wing like.

EMBRYO;

Cylindrical

HISTOLOGY OF RHIZOMES:26

T.S. of rhizome shows

1. Single layered epidermis which is externally cuticularized

2. Epidermis followed by parenchyma which are polyhedral& circular

3. Starch grains are seen in outer layers of parenchyma, these are concentric

striations, with hilum eccentric

4. Vascular bundles are scattered in parenchyma.

5. Xylem elements represented by trachea, tracheids and xylem parenchyma.

6. Phloem is composed of sieve tubes, companion cells and phloem parenchyma.

(ind drugs)

CHEMICAL CONSTITUENTS:27

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Tropolone alkaloids are the main chemical constituents, besides these alkaloids it

contain essential oil, Benzoic acid, 2-hydroxy-6-mehtoxybenzoicacid, Salicylic acid,

Choline, Dextrose, Palmic acid, Phytosterol including stigma-sterol, a mixture of

phytosterolins containing stigma sterol glycoside and some resinous matter, an

enzyme which readily hydrolyses amygdaline is present.

Major constituents:

Alkaloids: Colchicine and Superbine are two main alkaloids present in Gloriosa

superba.

Alkaloids with Tropolone ring :

Colchicine, 3-demethyl colchicines, N-deacetyl , N-formylcolchicine, Colchicecine,

Colchicoside, Cornigerine, -lumincolchicine, Colchicinamide

Minor constituents:

sitosterol, (24)-24 methylcholest-5-en-3-01, -24-ethylcholest-5-22-dien-3-01, 24-

ethylcholest-5-en-3-o1.

It contain bitter principle superbine( C32 H60N2O17) perhaps identical with scillotoxin28

SUBSTITUTES AND ADULTERANTS:29

A very common adulterant of this drug is Costus specious Sm., which is also

used as Kemuk in the Indigenous system of medicine as anthelmintic, anti-

inflammatory. Costus speciosus Sm. is sold in name of Gloriosa superba Linn. Both

the drugs can be distinguished macroscopically. Kebuk is brown in colour and has

bland odour and pungent taste

PROPOGATION AND CULTIVATION:30

The plant is grown from strong tubers. Gloriosa can be grown in almost all types

of soils, both by rhizomes and by seeds but best soil for growing this plant is sandy

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loom. Ploughing or digging 2-3 times to a depth of 15-20 cm works out the soil. The

soil is made uniform and finer by breaking soil particles. The beds are prepared

suitably. this is a rainy season plant therefore sprout well when temperature is warm

and humidity is high. Both the seeds and rhizomes are sown usually in the last week

of June to mid of July. As there are only two buds at the extreme ends in each

rhizome utmost care should be taken not to damage the rhizomes. The rhizomes are

planted by splitting into two from their 'V' or 'L' shaped joints or are placed s such in

the lines 20cms apart at the distance of 15-20 cm. The rhizomes are planted

horizontally 5-6 cm. deep. About 33-35kg of seeds or 10-12 quintals of rhizomes may

be sufficient for a hectare. They are watered moderately at the first but after green

shoots appear above the ground, 2-3 showers are given in a week. Usually creeper

takes 2-3 months time when they start wilting. Seeds are sown in lines at the distance

of 4-6 cm apart about 15-20 days are required for germination, 3-4 year are to mature

rhizome for blooming. The fruit ripen by the end of October and that the aerial shoot

eventually dies, leaving the fleshy rhizome remaining underground.

COLLECTION:

The rhizomes are dug out with great care during November to December and are

collected softly. Since rhizomes are very tender, therefore utmost care should be taken

while harvesting. The average yield is approximately 40-50quintals of rhizome and

10 quintals of seed per hectare.

DISTRIBUTION AND HABITAT:31

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AFRICA

Northeast Tropical Africa: Ethiopia; Somalia; SudanEast Tropica

lAfrica:Kenya; Tanzania; Uganda West Tropical Africa: Senegal

South Tropica lAfrica: Mozambique

Southern Africa: Botswana; Namibia; South Africa - Cape Province, Natal,

Transvaal; Swaziland

Western Indian Ocean: Madagascar

ASIA-TEMPERATE

China:

ASIA-TROPICAL

Indian Subcontinent: India; Nepal; Sri Lanka

Indo-China: Cambodia; Laos; Myanmar; Thailand; Vietnam

Malaysia: Indonesia - Celebes [s.], Java, Lesser Sunda Islands

FOLK PRACTICE:32

An extra-ordinary belief (superstition or tantric prabhava) is prevailed among

rural folks in certain areas of country, that if roots of Langali if kept in house of

someone may cause dispute & disturbance of relations between members of that

house or two neighbors. It can create difference or cause psychological bad effects.

Dosage:33

0.3gms-0.6gms is considered to be tonic

Dose upto 0.75 is not toxic but beyond that it has toxic effects

Toxic Signs and Symptoms of Langali:34

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If it is consumed in wet or dry form it causes Daruna Daha, Moha, Atisara, lastly

Vibrama

CLINICAL EFFECTS35

Acute poisoning

Ingestion: Acute manifestations begin two to six hour after ingestion and consist of

burning pain in the mouth and throat with thirst, followed by nausea, intense

vomiting, colicky abdominal pain and severe diarrhoea with blood, leading to hypo

tension an shock. Delirium, loss of consciousness, convulsions, respiratory distress,

haematuria, oliguria, transient leucocytosis followed by leucopenia, thrombocytopenia

with hemorrhages, anemia, muscle weakness which may progress to polyneuropathy

are seen in the second or third day. Alopecia occurs 1 to 2 weeks after intoxication as

a late manifestation in survivors.

Course, prognosis, cause of death The commonest clinical presentation of

poisoning is severe gastroenteritis with nausea, vomiting, diarrhoea with blood

leading to dehydration, hypovolaemic, shock and acute renal failure. Muscle

weakness, hypoventilation, ascending polyneuropathy, bone marrow depression and

coagulation disorders are the other features of poisoning.

Death in severe poisoning occurs due to shock or respiratory failure although

haemorrhagic or infective complications may cause death after the first day.

Systematic description of clinical effects

Cardiovascular

Heart - there is no direct effect on the heart, but fluid and electrolyte loss, often causes

hypovolaemic shock manifested by hypo tension and tachycardia.

Respiratory

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Respiratory failure is thought to be due to the paralysis of intercostal muscles

rather than the direct depression of the respiratory center by colchicine (Angunawela

& Fernando, 1971). The patient may be dyspnoeic and cyanotic.

Neurological

Central nervous system (CNS)

There is progressive paralysis of the central nervous system and peripheral

nervous system (Wijesundere, 1986). Confusion and delirium may develop either

secondary to poor cerebral perfusion or as a result of direct cerebral toxicity

(Ellenhorn et al., 1996). It may also cause convulsions, restlessness and coma.

Peripheral nervous system

Ascending polyneuropathy, weakness and loss of deep tendon reflexes

Skeletal and smooth muscle

Colchicine could have a direct toxic effect on skeletal muscles causing

muscular weakness. Rhabdomyolysis may occur with significant increase in muscle

enzymes and myoglobinuria as a result of direct muscular damage. Muscle weakness

that may persist for many weeks may contribute to respiratory deficiency

Gastrointestinal

Gastroenteritis including nausea, vomiting and diarrhoea with blood

accompanied by colic and tenesmus. Loss of fluids and electrolytes leads to

hypovolaemia.

Hepatic

Colchicine may exert direct hepatic toxicity with moderate cytolysis.

Urinary

Renal

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Any direct toxic effect of the toxin on kidney is not clear. Renal failure is

probably secondary to excess fluid loss or hypovolaemia and is preceded by oliguria

and haematuria. Proteinuria could also occur

Endocrine and reproductive systems

Vaginal bleeding has been reported as a feature of intoxication. Tubers are

used as an abortifacient in some countries.

Dermatological

Alopecia usually occurs one or two weeks after the ingestion of G. superba. A

case of generalized depilation has also been reported.

Desquamative dermatitis has been reported as another dermatologic manifestation.

Both these conditions can be attributed to the antimitotic activity of the colchicine and

gloriosine.

Eye, ear, nose and throat: local effects

Subconjunctival hemorrhages have been observed.

Burning and rawness of the throat may be early symptoms of toxicity.

Antidote :36

Mishri is given with Takra as Anupana, Ghritapana is advised.

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GOMUTRA

In classics gomutra is importance because of its potent properties and its

Kshareeya property. It is classified under mootra varg in all classics and mentioned as

shodhana dravya for various bheshaja.

Reference regarding Gomutra is available in Vedas, Purans and many

Dharmagranth; Gomutra is mentioned as one among Panchgavya. As cow is

worshiped as 'Nandini', even its byproducts are considered as auspicious and thus

used for various purposes. So Gomutra is known for its shodhana property of many

herbs.

Reference regarding Gomutra is available in all classics in mutra vargaand as

been prescribed in treatment of many disorders. Mainly its Kshar guna is highlighted

and mainly used preparations like Kshar basti etc.

Selection of cow:

Single coloured, lactating and healthy cow is preferred.

Time of collection:

Always collection is done in morning.

Chemical composition:37

It contains various minerals- copper, iron, calcium, sodium, magnesium,

potassium, phosphate, sulphur, chlorine, nitrogen, urea, uric acid, creatinine, purine

bases, vitamins( A, B, D, E), hip uric acid, aurum hydroxide, pigments- urochrome

and urobilin

In addition to that depending on food and health condition it may contain foreign

and pathological substances.

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Organic constitutes:

Urea - 45gms

Ammonia -1gm

Uric acid –2.5gm

Amino acids - 2.5gms

Inorganic constituents:

Chlorides -15gms

Nitrogen -50gms

Phosphates –1.2gms

Sulphates –1.3gms

Potassium – 2.8gms

Sodium - 5gms

Protein – Nil

Ketone bodies – Nil

Glucose – Nil

Distribution of nitrogen in %:

Urea N – 74.07%

Allantoin - 3.68%

Creatinine N – 6.07%

Ammonia N – 0.48%

Hip uric acid N – 4.18%

Purine base N - 0.056%

Uric acid – 0.59%

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Properties of Gomutra:

Properties of gomutra:

Acc to kayadeva nigantu:38

RASA: Katu, Tikta, Kshaya, Kinchit madhura.

GUNA: Teekshna, kshaariya, laghu.

VIRYA: Ushna.

KAGMA: Pachaka, agnideepaka, bhadaka, medhya.

DOSHAKRIYA: Kaphavata nashaka, pittakara.

ROGANASHAN: Kusta, gulma, udara, shwasa, arsha, pandu, shoola.

Acc to Raja nigantu:39

RASA: Katu, Tikta.

GUNA: Ushna, laghu.

VIRYA: Ushana.

KAGMA: Deepana, medhya.

DOSHAKRIYA: Kaphavatahara.

ROGANASHAN: Pittakara.

Acc to Sushruta:40

RASA: Katu, kshariya

GUNA: Teekshna, ushna, laghu.

KAGMA: Deepana, medhya.

DOSHAKRIYA: Kaphavata nashaka, pittakara.

ROGANASHAN: Shoola gulma, udara, anaha.

Acc to Yogaratnakara:41

RASA: Katu, Tikta, kshara.

GUNA: Ushna, laghu.

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KAGMA: Deepana, medhya, sara, lekhana.

DOSHAKRIYA: Kaphavata nashaka, pittakara.

ROGANASHAN: Shoola gulma, udara, anaha

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SHODHANA

Shodhana is done to remove the maladi vishas and impart more medicinal

property.

“Uddishtairoushadhai saarddha kriyate peshanam

Malavichchittaye yattu Shodhanam tadihochyate //( R. T.)42

SAMANYA SHODHANA FOR ALL VISHA :43

The visha drug is cut into small pieces keep it in gomutra. The drug should

completely soaked in gomutra. Change the gomutra daily and add fresh gomutra.

Repeat the same for 3 days. Dry it in sun light and store.

Effect of Shodhana:43

Tadeva yukti yuktam tu praan daayi rasayanam I

Pathyaashinaam tridoshagnam brimahanam veeryavardhanam II ( A.Pr.)

After shodhana the substance that has under gone shodhana is imparted with

medicinal properties, it becomes capable to subside all tridoshs, can do brimhana

karm, works as rasayana.

Shodhana of Langali:

“Langali shuddamayati dinam gomutrasamsthita /”

(Y.R.Vishaadikara) 44

Shodhana is done by soaking Langali in gomutra for one day

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