xanthogranuloma cases

8/9/2019 Xanthogranuloma Cases.

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XanthogranulomaXanthogranuloma

Deba P Sarma, MDDeba P Sarma, MD

OmahaOmaha


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F 18, left scapula nodule.F 18, left scapula nodule.


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CD 68


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X

I

XIIIa


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Comment:

Intact epidermis with a diffuse dermal proliferation of large cells

with angulated nuclei, abundant foamy cytoplasm, and well

defined cell borders.

The nuclei show inconspicuous nucleoli. Several multinucleated

Touton-type giant cells ase seen.

The cytoplasm of the cells stain for CD 68 and Factor XIIIa, but

not with S-100 and CD 1a.

The lesion is most commonly seen in children, but it can occur at

any age.

Diagnosis: Xanthogranuloma


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Male,30, right elbow lesion.Male,30, right elbow lesion.


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Diagnosis:Diagnosis:



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M 17 yrs, mid backM 17 yrs, mid back


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M 39, right nasal ala.M 39, right nasal ala.


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Diagnosis:Diagnosis:XanthogranulomaXanthogranuloma


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M 23, right nare.M 23, right nare.


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M,69, multiple indurated plaques,both upperM,69, multiple indurated plaques,both upper

arms, upper chest, face.arms, upper chest, face.


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Necrobiotic xanthogranulomaNecrobiotic xanthogranuloma


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ReferencesReferences

Necrobiotic XanthogranulomaNecrobiotic Xanthogranuloma

AReview of 17 Cases With Emphasis onAReview of 17 Cases With Emphasis on

Clinical and Pathologic CorrelationClinical and Pathologic Correlation

Angela J. Wood, MD; M. Veronica UragaAngela J. Wood, MD; M. Veronica UragaWagner, MD; Jared J. Abbott, MD, PhD;Wagner, MD; Jared J. Abbott, MD, PhD;Lawrence E. Gibson, MDLawrence E. Gibson, MD

Arch Dermatol.Arch Dermatol. 2009;145(3):2792009;145(3):279--284.284.

xanthogranuloma cases

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