what are the periodic paralysis triggers2 are the periodic paralysis triggers.pdfwith periodic...
TRANSCRIPT
What are the Periodic Paralysis Triggers?
“AVOID AT ALL COST”
There are many triggers that set the partial and total paralysis into motion. It is
important to discover these triggers because we need to stop the episodes, if
possible, in order to regain the quality of our lives and to prevent the damage
being done to our organs as the potassium shifts and depletes in our bodies.
This damage can lead to permanent weakness and disability.
In the case of people with Andersen-Tawil Syndrome, the paralysis leads to
tachycardia and serious arrythmias, including long QT intervals, which can
lead to cardiac arrest. Avoiding paralysis is absolutely necessary, due to these
life-threatening effects.
Triggers can include:
Diet:
Our diet can be one of the biggest contributors to episodes of paralysis. The
following are some of my offenders or those that have been reported to me or
I have found in the research :
Simple carbohydrates: sugar, white flour, etc.
Complex carbohydrates: some grains ie, wheat, etc.
Meat: mostly red meats,
Salt
Caffeine
MSG
Alcohol
Large Meals
Sleep:
All aspects of sleep have set my episodes into motion :
Falling asleep
During sleep
Waking up
Stress (Good)
Stress (Bad)
Dehydration
Fasting
Sitting too long
Changes in the weather
Fatigue
Heat
Cold
Exercise:
Some individuals have no problem with exercise but others may not be able to
tolerate any type of exercise or very little exercise. This is called “exercise
intolerance”. Episodes may develop soon after or the next day.
Rest after exercise: may set an episode into motion.
Medications
Many, many medications can set muscle weakness or paralysis into motion for people
with Periodic Paralysis. The following is a list compiled from my own known offenders,
some that others have told me about and some I found in my research.
If one must take something, it is better to begin with ¼ of a normal dose to make
sure it will work for you.
Saline Drips
Glucose Infusion: If an IV is needed, Mannitol can be used
Oral or Intravenous Corticosteroids
Muscle Relaxers
Beta Blockers
Tranquilizers
Pain Killers (analgesics)
Antihistamines
Puffers for Asthma
Antibiotics
Cough Syrups
Eye Drops to Dilate Eyes
Contrast Dye for MRI’s
Lidocaine
Anesthetics
Epinepherine
Adrenaline
Over-the-counter medications
Most over the counter medications, etc can set muscle weakness or paralysis into motion
for people with Periodic Paralysis. The following is a list of some compiled from my own
known offenders, some that others have told me about, and some I found in my research.
Cough Syrups
Eye Drops
Glycerin Enemas
NSAIDs
If the following ingredients are in any
products you use…you should stop
using them until you are sure they are
not causing symptoms:
Sodium Hydroxide
Edetate Disodium
Stearic Acid
They may be in any of the following:
Lotions
Oils
Hair dyes or colors
Antiperspirants
Enemas
Suppositories
Soaps
Shampoos
Shaving creams, foams
Toothpastes
Deodorants
Beauty products
Skincare products
Cosmetic products
Bath Salts
Emollients, Ointments, Creams
Hair sprays
Perfumes, colognes
Powders
Hair gels, oils, tonics, mousse
Unknown: I can follow all the rules and
still have episodes for unknown reasons.
(For those who have Andersen-Tawil Syndrome there are special medication precautions
due to the long QT interval issue and the possible risk of risk of torsades de pointes.
The list of medications to avoid in these cases is at the end of this page.)
The following are drugs that can cause muscle weakness: Found at: http://paralysis.myadversereaction.com/
All Drugs Associated with the Adverse Reaction of Muscle weakness
282 mep 292 frosst (phenacetin free) 5-fu 6-mercaptopurine
accolate accupril accutane acebutolol hydrochloride
acetaminophen acetaminophen and codeine acetaminophen with codeine
acetazolamide
acetylsalicylic acid acetylsalicylic acid ent ctd actonel actos
acupuncture acyclovir adalat adalat p.a.
adalat p.a.20 adalat xl adderall xr adrenalin
adriamycin adrucil advair advair diskus
advil advil cold & sinus aggrenox albamycin t
aldactazide aldactone aldomet aldoril
alendronate alesse alfenta allopurinol
alphagan ophthalmic alprazolam altace alti-diltiazem cd
amantadine amiloride/hydrochlorothiazide aminophylline amiodarone
amitriptyline amlodipine amoxil amphotericin b
ampicillin anacin anafranil analgesic
analgesics anaprox ancef ancotil
androcur anectine anthralin anti-hypertensive medication(s)
anti-inflammatory agents anti-nauseant (s) antiinfectives for systemic use
anturan
apa pen strep (vet) apo allopurinol apo furosemide apo hydro
apo trihex apo-bisacodyl apo-clonazepam apo-diazepam
apo-diltiaz cd apo-ferrous sulfate apo-ibuprofen apo-leflunomide
apo-levocarb apo-metoclop apo-metronidazole apo-nadol
apo-norfloxacin apo-omeprazole apo-oxazepam apo-oxtriphylline
apo-pravastatin apo-prednisone apo-sotalol apo-sulfatrim
apo-sulfatrim ds apo-triazide apo-warfarin apresoline
aralen arava aricept arimidex
aromasin artane arthrotec asa
asacol asaphen asaphen ec asasantine
asparaginase (erwinia) aspirin aspirin coated atacand
atacand plus atarax atasol atenolol
ativan atromid-s atropine atrovent
avalide avandia avapro avastin
avelox avirax avonex axid
azathioprine azithromycin aztreonam baciguent
baclofen baycol becloforte beclomethasone dipropionate
beclovent inhaler beconase beminal with c fortis benadryl
benzodiazepines benztropine mesylate berotec beta-blocking agents
betaloc betaseron betnovate-n ointment bezafibrate
bezalip sr biaxin biaxin xl bicarbonate
birch desensitizing agent birth control bisacodyl bisoprolol
black cohosh blood pressure pill blood thinner blood whole
bonamine botox botox cosmetic brexidol 20
bricanyl bromazepam bromocriptine budesonide
bupivacaine bupropion buscopan busulfan
cal-mag calcitonin calcium calcium & magnesium
calcium & vitamin d calcium carbonate calcium citrate calcium supplement
caltrate camptosar canesten capoten
captopril carbamazepine carbocal d cardilate
cardizem cardizem cd cardura carvedilol
casodex catapres catheters catheters urethral
ceclor cefaclor cefazolin cefotaxime
ceftazidime ceftriaxone cefuroxime cefzil
celebrex celestoderm v celestoderm v/2 celexa
centrum cephalosporin ceptaz cerivastatin
ces cesamet champix chlor-tripolon
chloral hydrate chlorhexidine chlorpromazine chlorpropamide
chlorthalidone choledyl cholestyramine chondroitin
chromium gtf (natural factors)
cimetidine cipralex cipro
ciprofloxacin cisapride cisplatin citalopram
clarithromycin clavulin climara clindamycin
clomipramine clonazepam clonidine clopidogrel
clorazepate cloxacillin clozaril co-trimoxazole
co-trimoxazole ds codeine coenzyme q10 cogentin
colace colchicine colisone combivent
comtan concerta conjugated estrogens copaxone
cophylac copper-7 cordarone coreg
corgard corticosteroid(s) cortisone cosopt ophthalmic
coumadin coversyl cozaar crestor
cuprimine cyanocobalamin cyclobenzaprine cyclomen
cyclopentolate hydrochloride
cyclophosphamide cycloserine cyclosporine
cyproheptadine cyproterone acetate cytadren cytarabine
cytosar cytosine arabinoside cytotec dalacin c
dalmane danazol dantrium intravenous dantrolene
dantrolene sodium dapsone daunorubicin decadron
deltasone demerol depakene depo-medrol
depo-provera dermovate desyrel detrol
detrol la dexamethasone dexedrine dextroamphetamine
dextromethorphan dextrose dextrose 5% in saline dextrose 5% in water
diabeta diabetes medications dialysis diamicron
diamox diane-35 diazepam dicetel
diclofenac diclofenac sodium didrocal digoxin
dilantin dilaudid diltiazem diltiazem cd
dimenhydrinate diovan diovan-hct diphenhydramine
diphenhydramine hydrochloride
diphtheria pertussis tetanus adsor diphtheria ptp adsorbed dipyridamole
disipal ditropan diuretic divalproex sodium
dm syrup docusate docusate sodium dom-atenolol
dom-captopril domperidone dostinex doxepin hydrochloride
doxorubicin doxycycline drixoral dulcolax
duragesic duralith dust mite suspal polyvalent acariens
dyazide
ebixa ec - asa edrophonium effexor
effexor xr elavil eldepryl eloxatin
eltroxin emla emla patch empracet
empracet 30 enbrel energix b enoxaparin
entero-vioform entrophen epinephrine epirubicin
epival epivir eprex eryc
erythromycin estrace estraderm estradot
estrogens ethanol ethiodan evening primrose oil
excedrine exelon ezetrol factor viii
famciclovir feldene felodipine femara
fenofibrate fentanyl fergon ferrous fumarate
ferrous gluconate ferrous sulfate flagyl flaxseed
fleet enema flexeril flomax florinef
flovent floxin fluanxol tab fluconazole
fludara fluid(s) fluids fluorouracil
fluoxetine flutamide fluticasone fluvastatin
fluviral fluvoxamine folate folic acid
folic acid (natural factors) folinic acid forteo fosamax
fragmin frisium fucidin furadantin
furosemide furoside fusidic acid gabapentin
gamma globulin garamycin garlic gelusil
gemcitabine gemfibrozil gemzar gen-fenofibrate micro
gen-simvastatin gentamicin ginkgo biloba ginseng
gleevec glibenclamide gluconorm glucophage
glucosamine glutamine glyburide glyceryl trinitrate
glycon granulocyte colony stimulating factor (g-csf)
grapefruit gravol
habitrol halcion haldol haldol la
halls throat haloperidol halotestin hay desensitizing agent
hctz hemodialysis heparin heparin lock flush solution
heparin low molecular weight
heparin sodium heptavax b herbs
herceptin hivid hormone replacement therapy
hormones
humalog humira humulin humulin 30/70
humulin-n humulin-r hycodan hydralazine
hydration hydrochlorothiazide hydrocortisone hydrodiuril
hydromorph contin hydromorphone hydroxycut - ephedra free hydroxyurea
hypertension medication hypotears ophthalmic hyzaar hyzaar ds
i.v. solutions ibuprofen icaps idamycin
igiv imdur imipenem imitrex
immune globulin intravenous (human)
immune serum globulin imodium imovane
imuran indapamide inderal indocid
indomethacin infantol influenza vaccine influenza vaccine swine
inh inhibace insulin insulin 30/70
insulin nph insulin regular intron a intubation
invirase ionamin irbesartan iron
iron dextran ismelin isoptin isopto carpine
isopto carpine 2% isopto carpine ophthalmic 2% isordil isosorbide
isosorbide dinitrate iv drug(s) not specified iv fluids ivig 10% cbs/hq (bayer)
jectofer k-dur kaletra kaopectate
kayexalate kemadrin keppra ketamine
ketoderm kidrolase kytril l-asparaginase
l-thyroxine labetalol lactulose lamictal
lamisil lamivudine = 3tc lamotrigine lanoxin
lansoprazole lantus lanvis largactil
lasix lecithin lectopam lescol
leucovorin leucovorin calcium levamisole levate
levodopa-carbidopa levodopa-carbidopa 100-25 levofloxacin levothyroxine
librium lidex lidocaine lin-pravastatin
linseed oil lioresal lioresal d.s. lipid modifying agent
lipidil lipidil micro lipidil supra lipitor
lisinopril lithium lithium carbonate lomotil
loniten loperamide lopid lopresor
lorazepam losartan losec lovastatin
lovenox loxapac loxapine lozide
lupron lupron depot luvox lyrica
macrobid macrodantin magcal (heavenly orchard) magnesium
magnesium hydroxide magnolax mandelamine marcaine spinal
marvelon mavik maxalt maxalt rpd
maxeran maxipime medroxyprogesterone melatonin plus time released (swiss herbal)
mellaril meloxicam meperidine meridia
mestinon metamucil metformin methadone
methimazole methotrexate methotrimeprazine methyldopa
methylprednisolone metoclopramide metoclopramide hcl metolazone
metoprolol metronidazole mevacor miacalcin nasal
micardis micardis plus micro-k extencaps midamor
midazolam migranal milk of magnesia milk of magnesia with cascara
min-ovral mineral oil minipress minocycline
minoxidil miocarpine ophthalmic 6% mirapex mirtazapine
mivacron mmr mmr 11 mobicox
mobiflex moditen modulon moduret
mometasone furoate monitan monocor monopril
morniflumate morphine morphine sulfate motilium
motrin ms contin msm multiple vitamins
multivitamine(s) muscle & back pain relief (medicine centre)
muscle relaxants mycostatin
myozyme nadolol nalfon naprosyn
naproxen narcan nardil naropin
nasonex nebcin nefazodone neoral
neptazane neupogen neuro-spasex neurontin
nexavar nexium niacin nifedipine
nifedipine xl nitro-dur nitrofurantoin nitroglycerin
nitrolingual nitrolingual spray nitrostat nizoral shampoo
noludar nolvadex norcuron norflex
norfloxacin norgesic forte normal saline nortriptyline
norvasc novamoxin novantrone novasen
novo venlafaxine xr novo-amiodarone novo-ampicillin novo-atenol
novo-bupropion sr novo-cilazapril novo-docusate novo-domperidone
novo-doxepin novo-flupam novo-furan novo-gesic 325mg
novo-hydrazide novo-levocarbidopa novo-levofloxacin novo-metformin
novo-mirtazapine novo-peridol novo-pramine novo-pramipexole
novo-salmol novo-semide novo-spiroton novo-tamoxifen
novo-trimel d.s. novo-triptyn novocain novolin 30/70
novolin 40/60 novomix 30 novorapid nozinan
nsaids nu-triazide nupercainal nyaderm preparations (nos)
nystatin ogen olanzapine(lilly) omeprazole
omnipaque omniscan ondansetron ophthalmic prep.
orgaran ortho-novum 2 mg orudis e os-cal d
ovral oxaliplatin oxazepam oxeze turbuhaler
oxybutyn oxybutynin oxycodone oxycontin
oxygen pacemaker packed red blood cells pain killers
pain medication pamidronate pantoloc pantoprazole
paracetamol paraplatin parethoxycaine pariet
paroxetine paxil pegasys rbv pegetron
penicillamine penicillin nos penta/3b pentazocine
pentothal pentoxifylline pepcid pepcid ac
pepto-bismol peptol percocet percodan
permax perphenazine persantine phenergan
phenobarbital phenyltrope ophth phenytoin phosphate
phosphate-novartis pico-salax plaquenil plaquenil sulfate
plasma exchange platelets plavix pms docusate calcium
pms sertraline pms-benztropine pms-indapamide pms-metformin
pms-morphine sulfate sr pms-sennosides pms-zopiclone potassium (nos)
potassium chloride pravachol pravastatin sodium pre-sate
prednisolone prednisone premarin premarin vaginal cream
prepulsid prevacid prexige prinivil
prochlorperazine procyclidine hcl prodiem progesterone
prograf prometrium pronestyl propine 0.1%
propine ophthalmic propofol propranolol propranolol hydrochloride
propyl-thyracil provera prozac pseudoephedrine
pseudoephedrine hcl pulmicort pulmicort turbuhaler purodigin
pyridostigmine bromide quinapril quinidine sulfate quinine
rabeprazole radiation radiotherapy ramipril
ranitidine rapamune ratio-diltiazem cd ratio-lactulose
reactine rebif red raspberry plus (tropical oasis)
reglan
remeron remicade reminyl reminyl er
renedil renografin-76 reserpine restoril
rhovane rhubarb ridaura risperdal
risperidone (janssen-ortho)
ritalin ritalin sr rituxan
rivasa rivotril robalate robatar
robax platinum robaxacet robaxacet-8 robitussion cough & cold
rythmol sabin salazopyrin salbutamol
salicylic acid saline saline solution salk vaccine
salmon oil salofalk sandimmune neoral sandostatin
sandostatin lar sandoz bisoprolol sandoz diltiazem cd sativex
saw palmetto schick test scour solution (veterinary) sebivo
seconal sectral seldane senna
sennosides senokot septra serax
serevent seroquel sertraline serzone
simvastatin sinemet sinemet cr sinemet cr 200/50
singulair slow-k sloyers sodium bicarbonate
sodium chloride sodium polystyrene solu-cortef solu-medrol
soriatane sotalol spiriva spironolactone
starnoc statex stelazine stemetil
steroid(s) stool softener streptokinase streptomycin
sublimaze succinylcholine chloride sudafed sufenta
sulcrate supeudol surfak surgam
surmontil suspal polyvalent sustiva sutent
symbicort turbuhaler symmetrel synphasic synthroid
tacrolimus tagamet talwin compound 50 talwin for injection
talwin tablet tamoxifen tapazole tarceva
taro-warfarin taxol tazocin tegretol
tegretol cr temazepam temodal tempra
tenofovir tenoretic tenormin tensilon
terazosin terbutaline tetanus diphtheria adsor adult
tetracycline
thalidomide theophylline theophylline sustained released
thyrogen
thyroid thyroid hormones thyroxine tiazac
ticar ticlid ticlopidine timentin
timolol timoptic timoptic 0.5% timoptic ophthalmic
timoptic ophthalmic 0.5% timoptic-xe ophthalmic tinzaparin tnkase
tobramycin tolbutamide tolifer plus topamax
toradol tracrium trandate travatan
trazodone trendar triadapin triazide
triazolam tricyclen trihexyphenidyl trilafon
trimipramine triphasil tropicamide tubersol
tussionex tylenol tylenol arthritis pain extended relief
tylenol extra strength
tylenol no.2 tylenol no.3 tylenol with codeine no.2 tylenol with codeine no.3
tylenol with codeine no.4 typhoid vaccine ultiva ultracaine ds
urecholine ursofalk vagifem valium
valium nos valium oral valproic acid valsartan
valtrex vanceril vancomycin vaseretic
vasotec venlafaxine ventodisk ventolin
ventolin for inhalation ventolin nebule(s) vepesid verapamil
verapamil hcl verapamil sr versed vfend
viagra vinblastine vincristine vioxx
visipaque vitalux vitamin a vitamin b
vitamin b complex vitamin b12 vitamin b6 vitamin c
vitamin d vitamin d & calcium vitamin e vitamin k
vitamins vivelle vivol voltaren
voltaren rapide warfarin water wellbutrin
wellbutrin sr wine xalatan ophthalmic xanax
xeloda xenical xolair xylocaine
xylocaine endotracheal xylocaine hcl xylocaine viscous zanaflex
zantac zaroxolyn zerit = d4t zestoretic
zestril ziagen zinc zithromax
zocor zofran zoloft zometa
zomig zopiclone zovirax zyban
zyloprim zyprexa
The following are drugs that can cause muscle paralysis:
All Drugs Associated with the Adverse Reaction of Paralysis
baclofen bactrim roche beclovent benadryl
benylin with codeine benztropine berocca c betaseron
bezalip sr biaxin bicarbonate black cohosh
bricanyl bromazepam bupivacaine buspar
caelyx calcium calcium chloride calcium gluconate
calcium lactate campain capoten carbamazepine
carboplatin cardizem casodex ceclor
ceftin cefuroxime sodium celebrex celexa
cerubidine chloroquine phosphate chlorpromanyl chlorpromazine
cholestyramine cipro ciprofloxacin citalopram
clindamycin clonazepam clopidogrel clopixol acuphase
clotrimazole cloxacillin clozaril co-trimoxazole
cocaine codeine codeine phosphate cogentin
colace combivent combivir comtan
conjugated estrogens contac c (ppa) contac cough cold & flu day
contac cough, cold & flu night time
copaxone coreg cortisone coumadin
crestor crystapen cyanocobalamin cyclomen
cyclosporine cytosine arabinoside d4t = stavudine dalacin c phosphate
dalmane dantrolene sodium decadron demerol
depo-provera desyrel detrol dexamethasone
dexatrim diane-35 diazepam dicetel
diclofenac diclofenac sodium didrocal diflucan
digoxin dilantin dilaudid diltiazem
dimetapp (ppa) diovan diovan-hct diphtheria pertussis tetanus adsor
diphtheria ptp adsorbed diprivan discase ditropan
dobutrex docetaxel docusate docusate sodium
domperidone dopamine hcl duragesic dyazide
ec - asa echinacea effexor effexor xr
elavil eltroxin empracet 30 enbrel
entero-vioform entrophen ephedrine epilepsy medication(s)
epimorph epinephrine epival estrace
ethanol ethrane euglucon exelon
ezetrol fenofibrate fentanyl ferrous sulfate
fiorinal c 1/4 flexeril flomax flovent
flovent hfa fluanxol fluax fluid(s)
fluogen fluorouracil fluoxetine fluticasone
fluviral folic acid fosamax frisium
furosemide gabapentin gammagard sd ganciclovir
garlic gatifloxacin gemzar gentamicin
ginkgo biloba glucophage glucosamine glyburide
glyceryl trinitrate glycopyrrolate glysennid gm-csf
gravol haldol haldol la haloperidol
heart medication(s) heparin herbal tea hormone replacement therapy
humira humulin-n humulin-r hyaluronidase
hycodan hydralazine hydrochlorothiazide hydrocortisone
hydromorphone ice packs igiv imdur
imitrex imovane indapamide inderal
indocid insulin insulin lente insulin nph
insulin toronto intron a intubation iodine
iron isoflurane kemadrin ketek
ketoprofen ketorolac ketorolac tromethamine (sabex)
kwellada
labetalol lactulose lamictal lansoprazole
largactil lasix levaquin levodopa-carbidopa
levofloxacin levophed levothyroxine lidocaine
lioresal lipid modifying agent lipitor lirugen
lithium loestrin lomotil loperamide
lopresor lorazepam losec lovenox
loxapine lupron depot lyrica m-eslon
macrobid magnesium manerix marcaine
marcaine 0.25% marcaine 0.5% with epinephrine
marvelon maxeran
medroxyprogesterone acetate
mefoxin meloxicam mepivacaine
meridia metformin methadone methimazole
methotrexate methyldopa-hydrochlorothiazide
methylprednisolone metoclopramide
metoprolol metronidazole micardis miconazole
midamor midazolam min-ovral minerals
minestrin 1/20 minocycline mirapex mirena
misoprostol mivacurium chloride mmr mmr 11
modafinil modecate morphine morphine sulfate
motrin multivitamine(s) muscle relaxants mycophenolate mofetil
myochrysine mysoline nadolol nasonex
navelbine neguvon nelfinavir neoral
neostigmine neurontin nevirapine niaspan
nicoderm nifedipine nightime cold lemon nitrogard sr
nitrolingual spray nitrong ointment nitrostat nitrous oxide
norcuron normal saline norvasc norvir
novasen novo-hydrazide novo-propoxyn novo-trimel
novolin nph novolin toronto nuvaring nyquil
omega - 3 omega 3-6-9 omeprazole ondansetron
oral contraceptives orbenin ortho-novum 2 mg ortho-novum sq
orudis-sr oxazepam oxybutyn oxycodone
oxycontin oxygen pain killers pain medication
pancuronium bromide pantoloc pantoprazole paroxetine
parsley tablets pavulon paxil pegetron
penglobe penicillin penicillin nos pentothal
percocet perindopril persantine pertussin compound 8
pethidine phenobarbital phenytoin plaquenil
platinol plavix pms-gabapentin pms-pravastatin
potassium (nos) potassium chloride prandase pravachol
pravastatin sodium prednisone premarin prevacid
prexige primaxin progesterone proparacaine hcl
propofol provera prozac pyridium
quad vaccine quelicin quetiapine quinine
quinine - odan quinine sulfate rabeprazole radiotherapy
ranitidine ratio-salbutamol-hfa rebif remeron
remicade risperdal risperdal m-tab risperidone (janssen-ortho)
ritalin ritalin sr rituxan riva k sr
rivotril robaxacet rocephin rocuronium
sabin salbutamol saline drip saline solution
salmocide (vet) salofalk sectral seldane
senna senokot septra septra d.s.
serevent sertraline simvastatin sinequan
singulair slow-k smallpox vaccine sodium bicarbonate
sodium phosphate oral solu-cortef solu-medrol somnol
sporanox stadol ns stemetil steroid(s)
stool softener streptase succinylcholine chloride
sucralfate
sufenta sulindac supeudol symbicort turbuhaler
symmetrel synarel synthroid syntocinon
tacrolimus talwin for injection talwin tablet tavist
tegretol temazepam temodal tequin
terazosin terfenadine tetanus diphtheria adsor adult
tetanus toxoid
tetracaine tetracycline thermo-x thiopental sodium
thyrogen thyroxine topiramate toradol
torecan total parenteral nutrition (tpn)
trandate trazodone
triphasil trivirix trusopt ophthalmic tubarine
tylenol tylenol extra strength tylenol no.2 tylenol no.3
tylenol with codeine no.3
ultiva valium valium injectable
valium nos vancomycin varicella vaccine varicella-zoster immune globulin (human)
vasotec vecuronium ventilation ventolin
viagra vincristine vinorelbine vio-bin scourade (vet)
vioxx visudyne vitamin ade (vet) vitamin c
vitamin d vitamin e vitamins vivol
warfarin wellbutrin wellbutrin sr wellbutrin xl
wydase xalatan ophthalmic xanax xylocaine 1.5% with epinephrine
xylocaine hcl xylocaine hcl 2% zanaflex zantac
zarontin zemuron zithromax zocor
zoloft zomig zopiclone zyban
zyprexa zyprexa zydis
Drugs to be avoided for use in patients with diagnosed or suspected
congenital long QT syndrome. (Drugs on our category-of-risk lists are
also included here.)
Drugs to be avoided for use in patients with diagnosed or suspected congenital long QT
syndrome. (Drugs on our category�of�risk lists are also included here.)
Generic Name Brand Name Class/Clinical Use Comments
Escitalopram Cipralex® Anti�depressant / Major
depression/ Anxiety disorders
Phenylpropanolamine Acutrim® Decongestant / allergies,
sinusitis, asthma
Amphetamine Adderall® CNS stimulant / ADHD
This includes dextroamphetamine and amphetamine / dextroamphetamine
combinations.
Phentermine Adipex® Appetite suppressant /
dieting, weight loss
Metaproterenol Alupent® Bronchodilator / asthma
Clomipramine Anafranil® Tricyclic Antidepressant /
depression
Dolasetron Anzemet® Anti�nausea / nausea,
vomiting
Chloroquine Aralen® Anti�malarial / malaria
infection
Moxifloxacin Avelox® Antibiotic / bacterial
infection
Trimethoprim�Sulfa Bactrim® Antibiotic / bacterial
infection
Diphenhydramine Benadryl® Antihistamine / Allergic
rhinitis, insomnia
Sotalol Betapace® Anti�arrhythmic / abnormal
heart rhythm Females>Males
Clarithromycin Biaxin® Antibiotic / bacterial
infection
Terbutaline Brethine® Bronchodilator / asthma
Ephedrine Broncholate® Bronchodilator,
decongestant / Allergies, sinusitis, asthma
Epinephrine Bronkaid®
catecholamine, vasoconstrictor /
anaphylaxis, allergic reactions
Nicardipine Cardene® Anti�hypertensive / high
blood pressure
Quinidine Cardioquin® Anti�arrhythmic / abnormal
heart rhythm Females>Males
Citalopram Celexa® Anti�depressant /
depression
Fosphenytoin Cerebyx® Anti�convulsant / seizure
Ciprofloxacin Cipro® Antibiotic / bacterial
infection
Clozapine Clozaril® Anti�psychotic / schizophrenia
Cocaine Cocaine Local anesthetic /
Methylphenidate Concerta® CNS stimulant / ADHD
Amiodarone Cordarone® Anti�arrhythmic / abnormal
heart rhythm Females>Males,TdP risk
regarded as low
Ibutilide Corvert® Anti�arrhythmic / abnormal
heart rhythm Females>Males
Perflutren lipid microspheres
Definity® Imaging contrast agent /
Echocardiography
Trazodone Desyrel® Anti�depressant /
Depression, insomnia
Tolterodine Detrol LA® Bladder Antispasmodic /
Tolterodine Detrol® Bladder Antispasmodic /
Phenylpropanolamine Dexatrim® Decongestant / allergies,
sinusitis, asthma
Amphetamine Dexedrine® CNS stimulant / ADHD
This includes dextroamphetamine and amphetamine / dextroamphetamine
combinations.
Fluconazole Diflucan® Anti�fungal / fungal
infection
Dobutamine Dobutrex® Catecholamine / heart
failure and shock
Methadone Dolophine® Opiate agonist / pain
control, narcotic dependence
Females>Males
Isradipine Dynacirc® Anti�hypertensive / high
blood pressure
Erythromycin E.E.S.® Antibiotic;GI stimulant /
bacterial infection; increase GI motility
Females>Males
Venlafaxine Effexor® Anti�depressant /
depression
Amitriptyline Elavil® Tricyclic Antidepressant /
depression
Erythromycin Erythrocin® Antibiotic;GI stimulant /
bacterial infection; increase GI motility
Females>Males
Lithium Eskalith® Anti�mania / bipolar
disorder
Gemifloxacin Factive® Antibiotic / bacterial
infection
Phentermine Fastin® Appetite suppressant /
dieting, weight loss
Felbamate Felbatrol® Anti�convulsant / seizure
Ofloxacin Floxin® Antibiotic / bacterial
infection
Dexmethylphenidate Focalin® CNS stimulant / ADHD
Foscarnet Foscavir® Anti�viral / HIV infection
Ziprasidone Geodon® Anti�psychotic / schizophrenia
Haloperidol Haldol® Anti�psychotic /
schizophrenia, agitation
When given intravenously or at higher�than� recommended
doses, risk of sudden death, QT prolongation and torsades
increases.
Halofantrine Halfan® Anti�malarial / malaria
infection Females>Males
Astemizole Hismanal® Antihistamine / Allergic
rhinitis No Longer available in U.S.
Droperidol Inapsine® Sedative;Anti�nausea /
anesthesia adjunct, nausea
Dopamine Intropine® Inotropic agent / heart
failure; hypotension; shock
Paliperidone Invega® Antipsychotic, atypical /
Schizophrenia
Isoproterenol Isupres® Catecholamine / allergic
reaction
Telithromycin Ketek® Antibiotic / bacterial
infection
Granisetron Kytril® Anti�nausea / nausea and
vomiting
Levofloxacin Levaquin® Antibiotic / bacterial
infection
Vardenafil Levitra® phosphodiesterase inhibitor
/ vasodilator
Norepinephrine Levophed® Vasconstrictor, Inotrope / shock, low blood pressure
Escitalopram Lexapro® Anti�depressant / Major
depression/ Anxiety disorders
Lithium Lithobid® Anti�mania / bipolar
disorder
Probucol Lorelco® Antilipemic /
Hypercholesterolemia No longer available in U.S.
Indapamide Lozol® Diuretic / stimulate urine &
salt loss
Isoproterenol Medihaler�Iso® Catecholamine / allergic
reaction
Thioridazine Mellaril® Anti�psychotic / schizophrenia
Sibutramine Meridia® Appetitie suppressant /
dieting, weight loss
Metaproterenol Metaprel® Bronchodilator / asthma
Methadone Methadose® Opiate agonist / pain
control, narcotic dependence
Females>Males
Mexiletine Mexitil® Anti�arrhythmic / Abnormal
heart rhythm
Domperidone Motilium® Anti�nausea / nausea Not available in the U.S.
Dronedarone Multaq® Anti�arrhythmic / Atrial
Fibrillation
Pentamidine NebuPent® Anti�infective /
pneumocystis pneumonia Females>Males
Phenylephrine Neosynephrine®
Vasoconstrictor, decongestant / low blood
pressure, allergies, sinusitis, asthma
Ketoconazole Nizoral® Anti�fungal / fungal
infection
Chloral hydrate Noctec® Sedative / sedation/
insomnia
Tamoxifen Nolvadex® Anti�cancer / breast cancer
Imipramine Norfranil® Tricyclic Antidepressant /
depression
Disopyramide Norpace® Anti�arrhythmic / abnormal
heart rhythm Females>Males
Ritonavir Norvir® Protease inhibitor / HIV
Diphenhydramine Nytol® Antihistamine / Allergic
rhinitis, insomnia
Pimozide Orap® Anti�psychotic / Tourette's
tics Females>Males
Levomethadyl Orlaam® Opiate agonist / pain
control, narcotic dependence
Amiodarone Pacerone® Anti�arrhythmic / abnormal
heart rhythm Females>Males,TdP risk
regarded as low
Nortriptyline Pamelor® Tricyclic Antidepressant /
depression
Paroxetine Paxil® Anti�depressant /
depression
Pseudoephedrine PediaCare® Decongestant / allergies,
sinusitis, asthma
Pentamidine Pentam® Anti�infective /
pneumocystis pneumonia Females>Males
Desipramine Pertofrane® Tricyclic Antidepressant /
depression
Oxytocin Pitocin® Oxytocic / Labor stimulation
Fenfluramine Pondimin® Appetite suppressant /
dieting, weight loss
Epinephrine Primatene®
catecholamine, vasoconstrictor /
anaphylaxis, allergic reactions
Midodrine ProAmatine® Vasoconstrictor / low blood
pressure, fainting
Procainamide Procan® Anti�arrhythmic / abnormal
heart rhythm
Tacrolimus Prograf® Immunosuppressant / Immune suppression
Procainamide Pronestyl® Anti�arrhythmic / abnormal
heart rhythm
Cisapride Propulsid® GI stimulant / heartburn Restricted availability;
Females>Males.
Albuterol Proventil® Bronchodilator / Asthma
Fluoxetine Prozac® Anti�depressant /
depression
Quinidine Quinaglute® Anti�arrhythmic / abnormal
heart rhythm Females>Males
Ranolazine Ranexa® Anti�anginal / chronic
angina
Galantamine Reminyl® Cholinesterase inhibitor / Dementia, Alzheimer's
Atazanavir Reyataz® Protease inhibitor / HIV
Risperidone Risperdal® Anti�psychotic / schizophrenia
Methylphenidate Ritalin® CNS stimulant / ADHD
Roxithromycin* Rulide® Antibiotic / bacterial
infection *not available in the United
States
Ephedrine Rynatuss® Bronchodilator,
decongestant / Allergies, sinusitis, asthma
Octreotide Sandostatin® Endocrine / acromegaly,
carcinoid diarrhea
Fluoxetine Sarafem® Anti�depressant /
depression
Terfenadine Seldane® Antihistamine / Allergic
rhinitis No longer available in U.S.
Sertindole Serdolect® Antipsychotic, atypical / Anxiety, Schizophrenia
Mesoridazine Serentil® Anti�psychotic / schizophrenia
Salmeterol Serevent® Sympathomimetic /
asthma, COPD
Sertindole Serlect® Antipsychotic, atypical / Anxiety, Schizophrenia
Quetiapine Seroquel® Anti�psychotic / schizophrenia
Doxepin Sinequan® Tricyclic Antidepressant /
depression
Itraconazole Sporanox® Anti�fungal / fungal
infection
Atomoxetine Strattera® norepinephrine reuptake
inhibitor / ADHD
Pseudoephedrine Sudafed® Decongestant / allergies,
sinusitis, asthma
Trimethoprim�Sulfa Sulfa® Antibiotic / bacterial
infection
Trimipramine Surmontil® Tricyclic Antidepressant /
depression
Sunitinib Sutent® Anti�cancer / RCC, GIST
Amantadine Symmetrel® Dopaminergic/Anti�viral / Anti�infective/ Parkinson's
Disease
Flecainide Tambocor® Anti�arrhythmic / abnormal
heart rhythm
Nilotinib Tasigna® Anti�cancer / Leukemia
Gatifloxacin Tequin® Antibiotic / bacterial
infection
Chlorpromazine Thorazine® Anti�psychotic/ Anti�emetic
/ schizophrenia/ nausea
Dofetilide Tikosyn® Anti�arrhythmic / abnormal
heart rhythm
Arsenic trioxide Trisenox® Anti�cancer / Leukemia
Lapatinib Tykerb® Anti�cancer / breast cancer,
metastatic
Lapatinib Tyverb® Anti�cancer / breast cancer,
metastatic
Moexipril/HCTZ Uniretic® Anti�hypertensive / high
blood pressure
Alfuzosin Uroxatral® Alpha1�blocker / Benign
prostatic hyperplasia
Bepridil Vascor® Anti�anginal / heart pain Females>Males
Albuterol Ventolin® Bronchodilator / Asthma
Solifenacin VESIcare® muscarinic receptor
anatagonist / treatment of overactive bladder
Voriconazole VFend® Anti�fungal / anti�fungal
Protriptyline Vivactil® Tricyclic Antidepressant /
depression
Lisdexamfetamine Vyvanse® CNS stimulant / ADHD
Levalbuterol Xopenex® Bronchodilator / asthma
Ritodrine Yutopar® Uterine relaxant / prevent
premature labor
Sparfloxacin Zagam® Antibiotic / bacterial
infection
Tizanidine Zanaflex® Muscle relaxant /
Azithromycin Zithromax® Antibiotic / bacterial
infection
Ondansetron Zofran® Anti�emetic / nausea and
vomiting
Sertraline Zoloft® Anti�depressant /
depression
Close Window Print Revised: 08/09/2010
Printed: 03/23/2011 Source: www.QTdrugs.org Drugs on the QT Drug Lists are reviewed on an ongoing basis to assure the evidence is still appropriate for their placement on their respective list. KEY
Drugs to be Avoided Drugs to be avoided for use in patients with diagnosed or suspected congenital long QT syndrome. (Drugs on our category� of�risk lists are also
included here, as are some additional drugs.)
Females > Males: Substantial evidence indicates a greater risk (usually > two�fold) of TdP in women.
Arizona Center for Education and Research on Therapeutics The Critical Path Institute Tucson, Arizona and Rockville, Maryland Funded in part by Agency for Healthcare Research and Quality grant 1 U18 HS10385
Disclaimer and Waiver The information presented is intended solely for the purpose of providing general information about health related matters. It is not intended for any other purpose, including, but not limited to, medical or pharmaceutical advice and/or treatment, nor is it intended to substitute for the users' relationships with their own health care/pharmaceutical providers. To that extent, by continued use of this program, the user affirms the understanding of the purpose and releases The Critical Path Institute, The University of Arizona, State of Arizona and Arizona Board of Regents from any claims arising out of his/her use of http://www.azcert.org/medical-pros/drug-lists/list-03.cfm?sort=Brand_name Drugs that are generally accepted by the QTdrugs.org Advisory
Board of the Arizona CERT to have a risk of causing torsades de pointes.
Generic Name Brand
Name Class/Clinical Use Comments
Chloroquine Aralen® Anti�malarial / malaria infection
Sotalol Betapace® Anti�arrhythmic / abnormal heart
rhythm Females>Males
Clarithromycin Biaxin® Antibiotic / bacterial infection
Quinidine Cardioquin® Anti�arrhythmic / abnormal heart
rhythm Females>Males
Amiodarone Cordarone® Anti�arrhythmic / abnormal heart
rhythm Females>Males,TdP risk
regarded as low
Ibutilide Corvert® Anti�arrhythmic / abnormal heart
rhythm Females>Males
Methadone Dolophine® Opiate agonist / pain control,
narcotic dependence Females>Males
Erythromycin E.E.S.® Antibiotic;GI stimulant / bacterial
infection; increase GI motility Females>Males
Erythromycin Erythrocin® Antibiotic;GI stimulant / bacterial
infection; increase GI motility Females>Males
Haloperidol Haldol® Anti�psychotic / schizophrenia,
agitation
When given intravenously or at higher�than� recommended
doses, risk of sudden death, QT prolongation and torsades
increases.
Halofantrine Halfan® Anti�malarial / malaria infection Females>Males
Astemizole Hismanal® Antihistamine / Allergic rhinitis No Longer available in U.S.
Droperidol Inapsine® Sedative;Anti�nausea / anesthesia
adjunct, nausea
Probucol Lorelco® Antilipemic / Hypercholesterolemia No longer available in U.S.
Thioridazine Mellaril® Anti�psychotic / schizophrenia
Methadone Methadose® Opiate agonist / pain control,
narcotic dependence Females>Males
Domperidone Motilium® Anti�nausea / nausea Not available in the U.S.
Pentamidine NebuPent® Anti�infective / pneumocystis
pneumonia Females>Males
Disopyramide Norpace® Anti�arrhythmic / abnormal heart
rhythm Females>Males
Pimozide Orap® Anti�psychotic / Tourette's tics Females>Males
Levomethadyl Orlaam® Opiate agonist / pain control,
narcotic dependence
Amiodarone Pacerone® Anti�arrhythmic / abnormal heart
rhythm Females>Males,TdP risk
regarded as low
Pentamidine Pentam® Anti�infective / pneumocystis
pneumonia Females>Males
Procainamide Procan® Anti�arrhythmic / abnormal heart
rhythm
Procainamide Pronestyl® Anti�arrhythmic / abnormal heart
rhythm
Cisapride Propulsid® GI stimulant / heartburn Restricted availability;
Females>Males.
Quinidine Quinaglute® Anti�arrhythmic / abnormal heart
rhythm Females>Males
Terfenadine Seldane® Antihistamine / Allergic rhinitis No longer available in U.S.
Mesoridazine Serentil® Anti�psychotic / schizophrenia
Chlorpromazine Thorazine® Anti�psychotic/ Anti�emetic /
schizophrenia/ nausea
Dofetilide Tikosyn® Anti�arrhythmic / abnormal heart
rhythm
Arsenic trioxide Trisenox® Anti�cancer / Leukemia
Bepridil Vascor® Anti�anginal / heart pain Females>Males
Sparfloxacin Zagam® Antibiotic / bacterial infection
Close Window Print Revised: 03/25/2008
Printed: 03/23/2011 Source: www.QTdrugs.org Drugs on the QT Drug Lists are reviewed on an ongoing basis to assure the evidence is still appropriate for
their placement on their respective list. KEY
Females > Males: Substantial evidence indicates a greater risk (usually > two�fold) of TdP in women
Arizona Center for Education and Research on Therapeutics The Critical Path Institute Tucson, Arizona and Rockville, Maryland Funded in part by Agency for Healthcare Research and Quality grant 1 U18 HS10385 Disclaimer and Waiver The information presented is intended solely for the purpose of providing general information about health related matters. It is not intended for any other purpose, including, but not limited to, medical or pharmaceutical advice and/or treatment, nor is it intended to substitute for the users' relationships with their own health care/pharmaceutical providers. To that extent, by continued use of this program, the
user affirms the understanding of the purpose and releases The Critical Path Institute, The University of Arizona, State of Arizona and Arizona Board of Regents from any claims arising out of his/her use of the website. http://www.azcert.org/medical-pros/drug-lists/list-01.cfm?sort=Brand_name
The following are links to other websites The following are links to other websites The following are links to other websites The following are links to other websites
with lists for meds to avoid if one has risk with lists for meds to avoid if one has risk with lists for meds to avoid if one has risk with lists for meds to avoid if one has risk
for long QT interval heart beat.for long QT interval heart beat.for long QT interval heart beat.for long QT interval heart beat. http://www.longqt.org/medications.html
http://www.sads.org.uk/drugs_to_avoid.htm
http://www.mayoclinic.org/long-qt-syndrome/types.html
http://www.longqt.org/PDFs/UpdatedDrugstoAvoidCard4-07.pdf
http://drugs.emedtv.com/medicine/qt-prolonging-medications.html
http://my.clevelandclinic.org/heart/disorders/electric/longqtsyndrome.aspx