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Wave Consulting Department of Mechanical Engineering Box 870276 Tuscaloosa, AL 35487 August 1, 2014 Dr. Daniel Fonseca Dr. Rick Houser The University of Alabama 1022 NERC Tuscaloosa, AL 35487 Dr. Fonseca and Dr. Houser: This document contains information for an EEG measurement device designed by Wave Consulting. The User’s Guide we spoke about earlier can be found in the appendix of this report. Thank you both for allowing our senior design team to work with you on this project. Sincerely, David Tubbs Team Communicator [email protected]

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Page 1: Wave_Consulting_Proposal_FINAL

Wave Consulting

Department of Mechanical Engineering

Box 870276

Tuscaloosa, AL 35487

August 1, 2014

Dr. Daniel Fonseca

Dr. Rick Houser

The University of Alabama

1022 NERC

Tuscaloosa, AL 35487

Dr. Fonseca and Dr. Houser:

This document contains information for an EEG measurement device designed by Wave Consulting. The User’s Guide we spoke about earlier can be found in the appendix of this report.

Thank you both for allowing our senior design team to work with you on this project.

Sincerely,

David Tubbs

Team Communicator

[email protected]

Page 2: Wave_Consulting_Proposal_FINAL

Wireless EEG Transmission Device

Submitted to: Dr. Daniel Fonseca and Dr. Rick Houser

Submitted by: Wave Consulting

Course: ME 490

Instructor: Dr. Marcus Ashford

Mechanical Engineering Department

The University of Alabama

Tuscaloosa, Alabama

August 1, 2014

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By signing this page, each team member agrees with the contents of the proposal.

Ryne Hill Technical Division/Finance/Safety Executive

Signature Date 08/01/2014 Taylor Jenkins Project Executive/Technical Division

Signature Date 08/01/2014 Mykalah Sundquist Evaluation Division/Technical

Signature Date 08/01/2014 David Tubbs Public Relations/Technical Division

Signature Date 08/01/2014 Trevor Turnbough Team Coordinator/Evaluation Division

Signature Date 08/01/2014

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Executive Summary

An Electroencephalography test (EEG) involves the amplification of bioelectric potentials, which are associated with neuronal activity of the brain. The EEG uses electrodes to measure brain waves, which are measured in Hertz. The purpose of this project was to design and develop a mobile device that employs an EEG 19 channel amplifier. Our design involves the use  of  our  client’s current Mitsar amplifier and WinEEG computer software. The helmet uses the same  electrodes  and  housing  units  that  our  client’s  Bio-Medical helmet uses on a neoprene cap with a chinstrap for durability and comfort. A wireless system is used to transfer the EEG data to the  client’s  personal computer.

The team divided into roles to promote organization, efficiency, and accountability. Taylor Jenkins was assigned the executive role; Trevor Turnbough was responsible for coordination; the evaluation and safety roles were run by Ryne Hill; Mykalah Sundquist was assigned the finance role; and David Tubbs headed the public role. Technical roles were divided among the team with data transfer headed by Taylor Jenkins and Trevor Turnbough, controls and instrumentation were headed by Mykalah Sundquist and Ryne Hill, and fabrication was led by David Tubbs.

The University of Alabama had many of the manufacturing capabilities that we used for the fabrication of this device including the 3D printing lab and Makers Space, both located in Hardaway Hall. The University of Alabama has allowed the use of its facilities and staff during this project.

The final project was delivered to the clients on July 31, 2014. Continued testing and future work is set to be carried out by graduate students in the department of Mechanical Engineering at The University of Alabama.

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Table of Contents

Introduction and Background ......................................................................................................... 1

Desired End Product ....................................................................................................................... 2

Design Requirements ...................................................................................................................... 3

Technical Approach ........................................................................................................................ 4

Project Timetable ............................................................................................................................ 6

Budget ............................................................................................................................................. 7

Facilities and Resources .................................................................................................................. 7

Team Organization.......................................................................................................................... 8

References ....................................................................................................................................... 9

Appendix ....................................................................................................................................... 10

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1

Introduction and Background

Electroencephalography (EEG) is the recording of brain activity. It uses scalp mounted

electrodes to measure fluctuating voltages within the neurons of the brain. EEG can be used to

diagnose ailments such as epilepsy, comas, and sleep disorders. A typical EEG test involves

electrodes  being  placed  on  the  patient’s  head  for  a  short  period  of  time,  usually  20  or  30  minutes.  

Figure 1 illustrates the greatest problem with current EEG systems: Placing individual sensors on

the patients scalp.

Figure 1. EEG test

A drawback with most conventional EEG tests is that the patients are required to be in the

same  room  as  the  testing  machine.  While  this  doesn’t  provide  any  severe  discomfort  to  the  

patient, it does make it difficult to diagnose some problems. For example, consider the use of an

EEG to help diagnose a sleeping disorder. The physician needs the patient to sleep naturally, an

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exceedingly difficult proposition for someone with a bundle of wires attached to their head. Even

smaller EEG systems consisting of a cap with several installed electrodes run via a ribbon cable

can still be a hassle.

A wireless EEG system with cap mounted electrodes would have many benefits for the

client and for the patient alike. A wireless set up is much easier to set up for both the person

administering the test and for the patient. Set up time for the test is decreased drastically, because

individual sensors don’t have to be placed one by one on the patients head, nor does the patient

need to be tethered directly to the computer. The wireless cap allows the test administrator to set

the cap up correctly on the individual much more quickly, and then simply go to his computer

and start administering the test. A benefit for the patient receiving the test is that they don’t have

to spend as much time at the testing facility or be restricted to the immediate vicinity of the

testing computer.

Desired End Product

The desired end product was a wireless EEG system that included EEG electrodes and a

wireless data transfer system. The desired end product was one that has already been tested and

proven reliable and safe.

This apparatus will be used with an existing testing device that is not mobile. Dr. Houser and

Dr. Fonseca were given the helmet with all of the sensors for the EEG, a document that outlines

how to use the product, and a tutorial presentation.

Deliverables:

Helmet with EEG sensors

Wireless data transfer system

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User’s  Manual

Wireless protocol documentation

Spare parts for future testing

Design Requirements

The functional requirements of the EEG data transfer system that Wave Consulting was

tasked with designing is an impedance checking and monitoring device and an amplifier capable

of  recording  raw  brain  waves  at  19  locations  according  to  the  “10-20”  international EEG

standard.

Physical design specifications were based on a cap design based on a large adult sized

head (59 to 63 cm circumference). The cap and amplifier have wireless connection capability

with real time recording up to 30ft.

The main design constraint for the EEG data transfer system was mobility. The housing

for the electrodes allows for easy administration of gel into the electrode to insure adequate

impedance. Completion date was August 2014.

It was also important to our client that we deliver a product under budget while still

meeting the needs and functional requirements. Since the project related to human subject

testing, we had to be careful not to do anything that could put the department at risk of lawsuit or

punishment. Certain ethical constraints were also presented since the project involved human

subject testing. The safety, health, and welfare of the patients were held paramount in the

performance of all EEG testing. Members of Wave Consulting acted in professional matters for

the client and patient as faithful trustees.

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Technical Approach

Figure 2. Technical Approach Flow Chart

Figure 2 illustrates a general overview of the technical approach used to complete this

project. The details of each step are explained below.

The problem statement was obtained and discussed with the clients to better understand

the overall scope of the project. Once the problem was defined, a meeting with Dr. Houser and

Dr. Fonseca was arranged to better define specific goals and needs for the final project.

The helmet that was selected for this project had to meet several requirements set forth by

the client. Those requirements are discussed in detail in other sections of this report and include

patient comfort and durability. Rresearch was done to ensure that a proper helmet is selected.

Once a helmet was selected, EEG electrode sensor research began.

The Wave Consulting team gathered data on existing EEG sensors to begin design work

on the EEG portion of the project. Once initial research was done, the team decided on a sensor

Research Helmet Designs Concept

Selection

EEG Sensor Research

Testing and Feedback

Adjustments

Sensor Selection

Finalization

Problem Definition

System Selection

Research Data Transfer Systems System

selection Assembly

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to use on the project. With a sensor selected, the team presented their work to the client for

approval.

When sensors were selected and a cap was constructed, wireless data transfer system

research began. Research was conducted on existing wireless data transfer systems to learn more

about how they work and to narrow the selection down. Once research was done on data transfer

systems, a system was selected by the team.

After all of the items were approved and purchased, the assembly of the system took

place. When the product was tested for a period of time to ensure it worked properly, the design

was finalized and submitted as a final product.

Throughout the entire process, several steps were completed simultaneously. As an

example, the EEG sensor selection and the wireless data transfer research were both going on at

the same time. Having steps that overlap encouraged the team to always be working on a

different aspect of the project.

Future work for this project is planned to be completed by Mechanical Engineering

graduate students. Plans for future work should involve signal testing with a low range function

generator. Details for a function generator that meets the needs of the project can be found in the

appendix of this report. Further human subject testing can begin once approval from The

University of Alabama IRB is gained by Dr. Houser and Dr. Fonseca.

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Project Timetable

Figure 3. Project Timetable

Figure 3 shows the timetable for our project over the summer. Based on the time frame,

the project concluded during the first week of August. The chart shows which tasks took up the

majority of the time. These included: testing the wireless system, the EEG sensor analysis, and

final assembly. While some tasks were done simultaneously, others were undertaken in a

sequential order.

4/7 4/17 4/27 5/7 5/17 5/27 6/6 6/16 6/26 7/6 7/16 7/26 8/5

Research Helmet Designs

Helmet Selection

Helmet Design Analysis

Finalization of Helmet Design

EEG Sensor Research

Sensor Selection

Analysis of EEG sensors

Assemble into Helmet

Research Data Transfer systems

Testing & Adjustments of cap

Testing of wireless systems

Carrying case design and build

Selected wireless systems

Final Assembly

Poster Fair

Final Presentation

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Budget

The cost to the client included a $2000 Design Clinic Fee for the use of Mechanical

Engineering resources. All hardware used to create the final project is listed below:

EEG Cap Prototype -$465

o Neoprene Cap x 2 - $40o EEG Electrodes x 2 - $250o Ear Electrodes - $30o Electrode Mounts x 25 - $42o Miscellaneous Cap items - $103

Wireless Data Transmission- $892

o RS232 Transceiver - $159o USB kit with Transmitter & Receiver - $210o Stream HD Wireless PC to TV - $147o Wireless USB Docking Station - $50o Battery Pack-$40o Miscellaneous Wireless Data Transmission items - $286

Total Expenses - $1357

Budget Remaining - $643

Facilities and Resources

Throughout our design process, Wave Consulting met in various rooms around campus.

These sites included room 236 in the Biology building, the ideaLab located on the ground floor

in Hardaway Hall as well as the Hardaway Hall computer lab.

Wave consulting used Dr. Keith Williams, Dr. Fei Hu, and Dr. Hwan Sik-Yoon and

their knowledge to assist in data transfer system selection. Additional faculty members including

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Dr. Marcus Ashford, Dr. Daniel Fonseca, Dr. Rick Houser, and Dr. Steve Thoma were also

consulted.

Team Organization

The team was divided into technical and non-technical divisions. The six non-technical

divisions consisted of an executive division, coordination division, finance division, evaluation

division, public division, and a safety division. Taylor Jenkins was in charge of the executive

division.  Taylor’s  job  was to supervise team activities and control the project focus as well as

maintain efficiency through time management. Trevor Turnbough was in charge of the

coordination division, his responsibilities included organizing and keeping records of group

meetings with the team, client, and/or professors and establishing coordination and

communication between team members. Ryne Hill headed the finance and safety divisions, he

performed economic analysis to ensure the project is within budget constraints and confirm

safety parameters for the product and ensure they are met. Mykalah Sundquist was in charge of

the evaluation division. Her job was to oversee that the product met the required level of quality

and the testing of the design, she also confirmed parameters for verifying the analysis and

presentation format. David Tubbs was head of the public division. David presented the proposal

and final product to the client and generated public interest in the project.

The technical division consists of three different sub-divisions; data transfer, controls and

instrumentation, and fabrication. Data transfer was led by Trevor Turnbough. This sub-division

consists statistical analysis of the wireless system for the 19 channel feedback design. Taylor

Jenkins and Ryne Hill were in charge of the controls and instrumentation. This sub-division

included the electrical setup and sensor calibration and will work in conjunction with data

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transfer to properly apply a wireless data transfer system. Fabrication was be led by Mykalah

Sundquist and David Tubbs. This sub-division consisted of building the helmet, sensor adapters,

wiring harness, and an ergonomic prototype.

References

Operation Manual (2012). Electroencephalographic System. Mitsar Co. Ltd.,

St. Petersburg, Russia. Copy in possession of author.

Operator’s  Manual  (2011).  tDCS Model 1300A Low-Intensity Stimulator. Soterix

Medical Inc., New York, NY. Copy in possession of author.

User Manual (2012). StarStim. Neuroelectrics Barcelona SL, Barcelona, Spain. Copy in

possession of author.

Rizzoni, G. (2005). Principles and Applications of Electrical Engineering (5th ed.). New York: McGraw-Hill.

Wheeler, A.J., & Ganji, A.R. (2010). Introduction to Engineering Experimentation (3rd ed.). Upper Saddle River, NJ: Prentice-Hall.

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Appendix

Appendix A-User’s  Manual

Wireless  EEG  User’s  Guide

Wave Consulting

August 2014

wave consulting

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Introduction The University of Alabama Mechanical Engineering student team of Ryne Hill, Taylor Jenkins, Mykalah Sundquist, David Tubbs, and Trevor Turnbough worked to develop a wireless EEG brain wave monitoring system. This document should be considered the  User’s  Guide  for  the  product. Future work is planned for graduate students in the Mechanical Engineering department at The University of Alabama. Proper documentation has been passed along to them to continue work.

Users Responsibility It is assumed that the Mitsar EEG amplifier and WinEEG software will be used with this system. As such, special care must be taken with these items. The literature provided with these systems specifically states that the use of outside sources of data transfer (wireless USB) could damage the systems. By using the wireless data transfer system on the existing amplifier, the user accepts all responsibility for damages that may occur. The user should be aware that any future warranty claims with Mitsar could be subject to scrutiny about proper usage of their products.

Safety Instructions All safety protocols set forth by Mitsar should be followed in using this system. Please reference the Mitsar Operation Manual to review safety instructions before use.

System Components The system, as delivered by Wave Consulting in August 2014, contained the items listed below. As stated before, an existing Mitsar amplifier and a WinEEG USB security key are required to create a functioning system.

Component Name Qty. EEG Cap with electrodes (Size: L) 1 6 ft. wiring loom (cap to amplifier) 1 3 ft. wiring loom (cap to amplifier) 1 Wireless USB transmitter 1 Wireless USB receiver 1 Ergonomic Pack 1 Battery Pack 1

Spares Qty. Spare electrodes with housings 2

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System Usage In setting up an EEG test, the following set of instructions should be followed. It is assumed that steps succeeding these are identical to current EEG testing procedure and thus not listed.

1. Select a wiring loom to be used. Different length wiring looms are provided to tailor a fit for patient comfort.

2. Plug loom into EEG cap and amplifier. a. The red connectors indicate the correct orientation of the loom. Each connector is

labeled either cap side or amplifier side. 3. Plug Wireless USB receiver into an open USB port on the test computer 4. Plug the USB cord from the amplifier into the wireless USB transmitter 5. Power the battery pack by depressing the power button

a. Green lights on the battery pack should be illuminated b. 2 lights should appear on the USB transmitter. The red light indicates power is

being delivered, the green light indicates the USB connection is established. This power supply provides power to the amplifier and wireless data transfer system

6. Once the system is powered, green lights should be illuminated on the wireless USB icon on the desktop.

a. The connection can be checked using the Warpia software 7. Based on testing set forth in the wireless protocol, the range of the system was found to

be 30 feet in a clear line of sight a. Though wireless transmission through a single wall is possible, it should be

avoided if possible

Steps past step #7 should follow standard EEG test administration.

Troubleshooting for the wireless system and EEG cap can be found in this document.

The useable range for this device was determined by the testing protocol shown in Appendix B below. The useable range was determined to be just under 30 feet with an open line of sight. The device was also successfully tested with two 5 inch walls in between the transmitter and receiver. This should allow testing to be done in an open classroom as originally requested by the client.

Troubleshooting The following section provides troubleshooting guidelines for the EEG cap and wireless system. Further troubleshooting advice, if required, can be found in literature provided with the Mitsar amplifier.

Cap Troubleshooting If an electrode is not reading properly

1. Verify wiring continuity in cap and loom a. Continuity can be checked with a voltmeter

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2. Verify pin connection in 25 pin connector 3. Verify battery charge level

a. Battery should be charged after four tests 4. Reboot WinEEG software 5. Restart system by turning off battery pack 6. Replace sensor with a spare electrode. Note: See electrode installation instructions below.

If an electrode housing falls out of place

1. Spare electrode caps can be found in the spare parts provided 2. Locate electrode housing and cap in proper hole location. Take care that the electrode

housing and cap line up with each other. Note: The housing should be on the inside of the EEG helmet and the white electrode housing cap should be on the outside of the EEG helmet. Please refer to other electrodes for proper installation.

3. Place a drift punch over the white electrode cap. Verify that the working surface below the cap is sturdy and flat. Swiftly impact the drift punch with a hammer several times to depress cap into housing.

4. Verify proper installation by comparing to other electrodes and stretching the neoprene. If upon stretching, the electrode stays in place, the electrode can be considered properly installed.

Wireless System Troubleshooting If wireless signal is lost

1. Verify power source is working 2. Check that lights are illuminated on Wireless USB receiver 3. Verify system stayed within useable range

a. If system is taken out of range, a reset of the power may be required 4. Confirm WinEEG software is operating correctly

a. If WinEEG is not responding: wait 10-20 seconds. If system does not regain working status, a restart is required

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Appendix B- Wireless Testing Protocol Wireless Testing Protocol

The following document explains the testing that will be completed once successful wireless data transmission is achieved. The purpose of this testing is to determine the usable range of the wireless device in both ideal and non-ideal conditions, which will be explained in further detail below. The results of this testing will be used to accurately describe to our clients the effective range of their new wireless EEG device.

The device being tested is a Warpia StreamHD wireless system. The system operates using ultra wideband radio waves and claims to have an effective range of up to 30 ft. The USB dongle operates on a point to point basis, where their maximum range is achieved when they are in line of sight. The conditions that the device will be tested under are going to replicate how the device will be used for our wireless EEG application.

To test, the wireless dongle (PC adapter) will be plugged into a personal computer. The other wireless dongle (device adapter) will be plugged into the Mitsar EEG amplifier. The device adapter and the amplifier will both be placed inside the ergonomic backpack that will be included when we present the product to the clients.

Testing under Ideal Conditions:

To test under ideal conditions, the PC adapter will be plugged into the computer and the device adapter plugged into the amplifier and inside the pack. Once the dongles are connected, we will run the WinEEG software, which will work properly until we reach a distance where the dongles become disconnected, or the data transfer rate becomes too slow. At either of these instances, the WinEEG software will stop the test and display a message that tells us there was a data transmission error involving the amplifier.

A team member will walk with the amplifier, away from the PC, in a direct line of sight with the PC, until the system loses connectivity. When connectivity is lost, the team member will stop walking, and the distance between them and the PC will be measured in feet. This will be the effective distance, under ideal conditions, that the wireless device will transfer data. In order to make this distance measurement as accurate as possible, this test will be performed four times, in multiple directions, and the average distance of those tests will be found and recorded as the effective range.

Testing under Non-Ideal Conditions:

To test under non-ideal conditions, the PC adapter will be plugged into the computer and the device adapter plugged into the amplifier and inside the pack. Once the dongles are connected, we will run the WinEEG software, which will work properly until we reach a distance where the dongles become disconnected, or the data transfer rate becomes too slow. At either of these instances, the WinEEG software will stop the test and display a message that tells us there was a data transmission error involving the amplifier.

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A team member will walk away from the PC, similarly to what was done in the ideal test, but this time will go around a wall and continue to walk until the error message appears. At the point, the member will stop walking, and the distance will be recorded in feet. This test will also be run five times in order to get a more accurate average.

Because the wireless system that is being used works on a line of sight basis, we do not believe that it will successfully transmit data beyond one wall. But, a test will also be performed with a member walking around one wall and then another. If the system displays an error message before the second wall is reached or as the second wall is passed, we will state that the product is not to be used beyond one wall.

There have been some concerns about Wi-Fi and cell phone usage causing interference. Since the system is ultra wideband radio, it operates at a different range than Wi-Fi and cellular, so no interference should be received. To be sure of this, we will run the same test as described above, but while making phone calls and using the Wi-Fi. When performing these tests, the average distances will be compared to the distances that were recorded earlier. If we find that there is any interference, it will be noted in the user manual.

Test Results

All test results found during these testing periods will be recorded and inserted into the user manual that will be provided to the clients. Any noticeable interference that we find will also be inserted into the user manual.

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Appendix C- Document for future work Continuation of Wireless EEG Project

This outline is a summary of our project, describing what we did and the resources that we used as a team. We hope that the information provided will help with the continuation of this wireless EEG project. The summary will be broken up into two categories, cap design and fabrication, and wireless data transmission.

Cap Design

We started the project out with a bare 2.5mm swim cap. We then ordered EEG electrode disks from electro-cap, along with the appropriate electrode disk holders. We used insulated wiring from EEG electrodes that we already had, but this wiring can also be ordered from the electro-cap website if you would like to duplicate our cap. We ran all of the wiring from the electrodes to a 25-pin D-sub female crimp connector that was purchased from the local RadioShack. The red ergonomic piece that the wires run through was made by one of our group members in SolidWorks. He will stay on campus for the fall semester, so he can give you the file if you would like, and we will include his information at the bottom of the document if you need to contact him for any reason. Links for all of the items mentioned above can be found below:

2.5 mm Neosport cap: http://www.amazon.com/NeoSport-Wetsuits-Premium-Neoprene-2-5mm/dp/B003554EFE

EEG electrode disks, holders, gel and wiring: http://www.electro-cap.com/index.cfm/supplies/

Note: The electro-cap link will take you to their supplies page, but you have to call them to order the supplies that you need using the part numbers next to each product.

25 pin D-sub crimp female connector: http://www.radioshack.com/product/index.jsp?productId=2102865

Wireless System Design:

We first ordered a Cables Unlimited  wireless  USB  set  that  wasn’t  compatible  with wireless mice and keyboards, so it gave us a lot of trouble. The second system we ordered was the newer version of the Cables Unlimited system, which did support devices like mice and keyboards. This system was also unsuccessful. The successful system that was used is a Warpia wireless USB system. All of the paperwork and set up/installation guides that were included with the wireless systems will be given to the client. Links for all of these devices are provided below:

Cables unlimited system 1 (no mouse support): http://www.amazon.com/s/ref=nb_sb_noss_1?url=search-alias%3Delectronics&field-

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keywords=cables+unlimited+wireless+usb&rh=n%3A172282%2Ck%3Acables+unlimited+wireless+usb

Cables unlimited system 2 (mouse support): http://www.amazon.com/Cables-Unlimited-DisplayDock-Wireless-Docking/dp/B003D1CBY6/ref=sr_1_cc_1?s=aps&ie=UTF8&qid=1405974142&sr=1-1-catcorr&keywords=cables+unlimited+wireless+usb

Warpia StreamHD (successful system)

http://www.amazon.com/Warpia-StreamHD-Wireless-Full-1080P/dp/B004GTN0T4

Team Member Contact Information:

This is the information of the team member that will remain at school in the Fall. You may contact him with any questions that you have about the project. Feel free to call, text or email. He’ll  be  on  campus  Tuesdays  and  Thursdays.

-Ryne Hill

[email protected]

-678.447.6453

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Appendix D-Function Generator Information The following function generator can be used to test the EEG cap. Wave Consulting was unable to test due to time constraints of ordering this system. http://www.mtiinstruments.com/products/precisionsignalsource.aspx