WATER SOLUBLE VITAMIN D31ST

EVER AVAILABLE WATER SOLUBLE POWDER OF VITAMIN D3

A PRODUCT OF

HYBRID-NANOENGINEERING™

Market

This market is projected to reach about $2.5 Billion by 2020 at a CAGR of 11%.

PROBLEM?POOR BIOAVAILABILITY!

The market is over saturated with Vitamin D supplements that aren’t doing all that much for us. Why? Poor bioavailability!

OUR SOLUTION

• 100% Bioavailable Formulation As;

• Dry powder, one capsules a day to keep you Fit.• The 1st product of its kind in the market

CONVERSION OF VITAMIN D TO THE ACTIVE FORM

Cholesterol from diet

7 dehydrocholesterol in the skin

Sunlight converts 7-dehydrocholesterol to previtamin D3

Cholecalciferol(Previtamin D3)

The liver converts previtamin D to 25-hydroxyvitamin D which appears in circulation.

25-hydroxyvitamin D(circulating form)

The kidneys and other tissues convert it to an active form of 1,25-dihydroxyvitamin D

1,25-dihydroxyvitamin D(active form)

VITAMIN D AND CHRONIC DISEASES

– Regulating calcium and phosphate metabolism for bone health,

– Autoimmune diseases,– Atopic dermatitis,– Cardiovascular disease, – Chronic respiratory

diseases– Crohn’s disease and

Inflammatory bowel disease,

– Diabetes, type 1 and type 2

– Kidney disease,– Osteoarthritis, – Periodontal disease,– Rheumatoid arthritis, – Skin disorders,– Some cancers,– Infectious disease, – Schizophrenia

1,25-dihydroxyvitamin D plays an important role in:

RDARecommended Dietary Allowances (RDAs) for Vitamin D

Age Male Female Pregnancy Lactation0–12 months* 400 IU

(10 mcg)400 IU

(10 mcg)

1–13 years 600 IU(15 mcg)

600 IU(15 mcg)

14–18 years 600 IU(15 mcg)

600 IU(15 mcg)

600 IU(15 mcg)

600 IU(15 mcg)

19–50 years 600 IU(15 mcg)

600 IU(15 mcg)

600 IU(15 mcg)

600 IU(15 mcg)

51–70 years 600 IU(15 mcg)

600 IU(15 mcg)

>70 years 800 IU(20 mcg)

800 IU(20 mcg)

Institute of Medicine, and Endocrine Society Recommended Vitamin D intake (2011)* Adequate Intake (AI)

FOOD SOURCES OF VITAMIN D

FoodIUs per serving Percent DV

Cod liver oil, 1 tablespoon 1,360 340

Swordfish, cooked, 3 ounces 566 142

Salmon (sockeye), cooked, 3 ounces 447 112

Tuna fish, canned in water, drained, 3 ounces 154 39

Orange juice fortified with vitamin D, 1 cup 137 34

Milk, nonfat, reduced fat, and whole, vitamin D-fortified, 1 cup 115-124 29-31

Yogurt, fortified with 20% of the DV for vitamin D, 6 ounces 80 20

Margarine, fortified, 1 tablespoon 60 15

Sardines, canned in oil, drained, 2 sardines 46 12

Liver, beef, cooked, 3 ounces 42 11

Egg, 1 large (vitamin D is found in yolk) 41 10

Ready-to-eat cereal, fortified with 10% of the DV for vitamin D, 1 cup 40 10

nih.gov

FITNESS• What it'll do for you: Vitamin D's main job is to increase the flow of calcium into the bloodstream by promoting the absorption of calcium and phosphates from food in the

intestines and the reabsorption of calcium in the kidneys. That means vitamin D plays a key role in maintaining strong bones and protecting against osteoporosis. Experts and recent studies say Vitamin D plays a role in a few other positive effects as well:

• Improves longevityStudies of more than 57,000 subjects found that people taking supplements with at least at least 500 IUS of vitamin D were seven percent less likely to die than those who didn't take daily supplements. Researchers credited this to the protective effect of vitamin D against diseases—including cancer—and the vitamin's possible boost of blood vessel efficiency and the immune system.

• Lowers the risk of heart diseaseResearchers at the Intermountain Medical Center Heart Institute in Murray, Utah, studied 9,400 patients whose blood tests revealed low vitamin D levels during a routine trip to the doctor. The patients who raised their vitamin D levels by their next follow-up were 33 percent less likely to have a heart attack and 20 percent less likely to develop heart failure compared to their counterparts who did not increase vitamin D levels.

• Prevents high blood pressureIt has been noted that blood pressure is often elevated during the winter—when the body is producing lower levels of vitamin D through sunlight. This suggests a possible direct correlation between higher levels of vitamin and low blood pressure levels.

• May lower risk of certain cancersEuropean researchers have found that people with higher blood levels of vitamin D have a much lower risk of colon cancer. In one study, doctors examined the lifestyles of more than 520,000 patients between 1992 and 1998. The results, which were reported in January of this year, found that those with the highest blood levels of vitamin D had a nearly 40 percent decrease in colorectal cancer compared to those with the lowest levels.

• Helps fight against influenzaAfter a four-month long study of Japanese schoolchildren, researchers found that taking vitamin D supplements during the winter and early spring help prevent seasonal flu and asthma attacks. There was no consideration of the effects of the supplements on adults but other studies have found that vitamin D dramatically stimulates natural killer cells and play a major role in protecting the lungs from infection.

• Reduces muscle painLimited research has reported vitamin D deficiency in patients with low-back pain, and that supplementation may help to reduce the pain. Supplements may also help with chronic fatigue, headaches and other types of pain.

• Suggested intake: The recommended intake of vitamin D for males up to 50 years old is 200 IU (or 5 micrograms) and increases 200 IUs every 20 additional years. "The average man seems to be deficient in many vitamins, especially vitamin D," says registered dietitian and American Dietetic Association spokesperson Jim White. Not surprisingly, he recommends a varied diet. White adds that the richest sources of vitamin D are egg yolks, some types of fish (salmon, tuna and mackerel), butter, liver and cheese. "But it is important to stay within you calorie needs," White adds.

• It's been reported that 10 to 15 minutes of sunshine three times a week is enough to prevent deficiencies. However, many people living in sunny climates still do not make enough vitamin D and need more from their diet or supplementation. "Individuals with limited sun exposure need to include good sources of vitamin D in their diet or take a supplement," White adds.

• Those who take a multivitamin should note that most pills do include vitamin D, usually in strengths from 50 IU to 1,000 IU. White says supplements are okay to take but that you should consider the IUs you're already getting from your diet and work with your doctor to find a supplement that supplies the right amount of IU's for your diet or lifestyle.

• How important is vitamin D? Deficiencies have now been linked to types of cancers, heart disease, depression, weight gain, muscle pain and other maladies. "Lack of vitamin D may lead to a condition called rickets, especially in children, in which bones and teeth are weak," explains White. "In adults it may cause a condition called osteomalacia, in which calcium is lost from bones so that they become weak. This is very rare in men but has been seen in extreme cases."

Dr. Mewa Singh609-902-7128

Meda Biotech llc.mynanoview@gmail.com

www.nanomeda.comwww.nanosgroup.in

Hybrid-Nanoengineering™

(Solubilized Vitamin D3)

SMART-D3Highly bio-available

Nutritional Information ( Approximate values)Each serving/one capsule contains;Energy 6.14 KcalCarbohydrate 0.11gProtein 0.18gFat 0.55gCholecalciferol 2000IU

Other ingredients: Magnesium,starch, microcrystalline cellulose, Turmeric

Uses : Dietary supplement, one capsuleDaily. Store at dry cool place

Marketed By;AyurvedicDoc.comBaton Rouge, LAUSA

Highly Bio-available productNot for medicinal useCaution : Do not use if allergic toAny contentNo artificial color used

MFG Date : BEST USE WITHIN 24 MONTHS

Manufactured in association with Meda Biotech using Hybrid Nanoenginring 30

Capsules

SMART-D3(Solubilized Vitamin D3)

Highly bio-available

Nutritional Information ( Approximate values)Each serving/one capsule contains;Energy 6.14 KcalCarbohydrate 0.11gProtein 0.18gFat 0.55gCholecalciferol 2000IU

Other ingredients: Magnesium,starch, microcrystalline cellulose, Turmeric

Uses : Dietary supplement, one capsuleDaily. Store at dry cool place

Marketed By;AyurvedicDoc.comBaton Rouge, LAUSA

Highly Bio-available productNot for medicinal useCaution : Do not use if allergic toAny contentNo artificial color used

MFG Date : BEST USE WITHIN 24 MONTHS

Manufactured in association with Meda Biotech using Hybrid Nanoenginring 30

Capsules