volodymyr v.popov, leonid l.sytar, olexandr a. bolshak, gennady v..knyshov ny 2010 national amosov...

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V olodymyr V. Popov , Leonid L.Sytar , Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING TAPE OPERATION (WTO) FOR POSTSTENOTIC ANEURYSM OF THE ASCENDING AORTA

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Page 1: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Volodymyr V.Popov, Leonid L.Sytar ,

Olexandr A. Bolshak, Gennady V..Knyshov

NY 2010

National Amosov Institute of Cardio-Vascular Surgery

Kyiv, Ukraine

WRAPPING TAPE OPERATION (WTO) FOR POSTSTENOTIC ANEURYSM

OF THE ASCENDING AORTA

Page 2: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Aim

To evaluate different methods to correct poststenotic aneurysm of

the ascending aorta (PAAA)

Page 3: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Patient data

Term of the study: 1996 – 2008 yearsn = 442 pts with AS

Age 21 – 71 years, mean 55,1 + 7,5 yearsSex: male - 281 (63,6%)

female - 161 (36,4%)Functional class NYHA: II - 7 (1,6%)

III – 173 (39,1%)IV – 262 (59,3%)

Total – 442 – 100%

Page 4: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Causes of ascending aortic aneurysm

n %

Atherosclerosis, hypertension 296 67,0

Rheumatic fever 140 31,6

Bicuspid aortic valve 3 0,7

Other causes 3 0,7

Total 442 100,0

Page 5: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Operations for PAAA

Methods Quantity of patients

n (%)

AVR+Wrapping Tape Operation 157 35,5

Bentall+Wheat operations 46 10,4

AVR without correction of PAAA 239 54,1

Total 442 100,0

Page 6: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Variations of wrapping operations for PAAA during AVR

Methods Quantity of patients

n (%)

Wrapping tape operation (WTO) 54 34,4

WTO + resection of AAA 18 11,5

WTO + resection of AAA+ plasty of sino-tubular junction (STJ) in area of non-coronary cusp

54 34,4

WTO + plasty of STJ 31 19,7

Total 157 100,0

Page 7: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Methods of surgical treatment of PAAA (n = 442 pts)

All operations were performed with CPB, moderate hypothermia (28-34 C), retrograde crystalloid cardioplegia.

Cell-saver wasn’t use in any case.

Cross-clamping time 79,7 ± 8,2 minutes (group A), 65,5 ± 11,5 minutes (group B) and 121,3 ± 23,1 minutes (group C) (p < 0.05). Blood loss: 285,4±39,4 ml (group A; 19,7% got no donor blood), 425,4±59,4 ml (group B) and 635,1 ± 71,5 ml (group C) (p < 0.05). ICU stay: 55,2 ± 6,1 hours (group A), 58,8 ± 7,2 hours (group B) and

83,4 ± 8,7 hours (group C) (p < 0.05).

Page 8: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Results of operations for PAAA

Methods

Quantity of patients

nHospital mortality

(%)

AVR+Wrapping tape operation 157 0,6

Bentall +Wheat operations 46 6,5

AVR without correction of PAAA 239 1,3

Page 9: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Echo data of PAAA during surgical treatment

Method of treatment

Diameter of ascending aorta (cm)

Before operation

Hospital period

Remote period

AVR+WTO 4,9±0,5 4,0±0,3 4,1±0,2

Benthal’s/ Wheat’s operations

6,5±0,7 3,0±0,3 3,1±0,3

AVR without correction of PAAA

4,8±0,4 4,7±0,3 5,4±0,5

Page 10: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Remote results (n=421 – 96,3 % of discharged patients)

Result WTO Bentall/ Wheat operations

AVR

n % n % n %

Good 87 57.6 21 48.8 49 21.6

Satisfactory 59 39.1 19 44.2 140 61.7

Unsatisfactory 3 2.0 2 4.7 25 11.0

Died 2 1.3 1 2.3 13 5.7

Total 151 100.0 43 100.0 227 100.0

Average term of observation 6,5±0,5 ys

Reoperations (AA’s replacement) – 2,2 % (n=5/227) only in group of AVR without PAA’s correction

Page 11: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Actual analysis of mortality and stability of good and satisfactory results in a remote

period (n=421)

Page 12: Volodymyr V.Popov, Leonid L.Sytar, Olexandr A. Bolshak, Gennady V..Knyshov NY 2010 National Amosov Institute of Cardio-Vascular Surgery Kyiv, Ukraine WRAPPING

Conclusions

On the basis of clinical experience we recommend the expedient method of WTO for PAAA (diameter of AA ≤ 5,5 cm) during AVR without AA replacement.

Reconstruction of AA with PAAA by WTO is safe and should be performed in cases with AA diameter of 4,5-5,5 cm.