visceral debranching and stenting (hybrid) for complex aaa ... · conclousion •hybrid repair may...

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Visceral debranching and stenting (hybrid) for complex AAA repair Ahmad Gamal. Professor of vascular surgery Cairo University.

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Page 1: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Visceral debranchingand stenting (hybrid) for

complex AAA repair

Ahmad Gamal.

Professor of vascular surgery

Cairo University.

Page 2: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Disclosure

• Speaker name:

.................................................................................

• I have the following potential conflicts of interest to report:

• Consulting

• Employment in industry

• Stockholder of a healthcare company

• Owner of a healthcare company

• Other(s)

• I do not have any potential conflict of interest

Page 3: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

The term ‘complex aneurysm’ refers toaneurysms of the upper abdominal aorta thatinvolve any combination of its visceral branchessuch as renal, superior mesenteric or coeliacvessels

Complex aortic aneurysm

Page 4: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Tre

atm

en

t o

pti

on

s

Open repair

Hybrid

Endovascular

(T-branch/chimney/fenestration)

Page 5: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Open repair

• safe, effective, and durable inthe long-term

• Perioperative mortality:

JAA: < 7%

TAAA: 6-40%

• Supra renal/ aortic crossclamping.

• Renal dysfunction: 10 – 40%

Page 6: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Endovascular repair

• Using chimney, fenestrated and branched grafts

• Decreased the operative mortality (5-10%).

• Complex and require very sophisticated endovascular equipment and skills.

• Limited availability

• High cost

• Durability?

Page 7: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Visceral hybrid debranching

Page 8: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative
Page 9: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Advantages

1) No thoracotomy:

i. fewer pulmonary complications

ii. fewer cardiac arrhythmias

iii. less pain.

2) Reduced hypothermia with subsequent reduction in:

i. coagulopathy;

ii. cardiovascular instability.

3) Applicable to a wide range of patient anatomy

Page 10: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Advantages

4) Reduced duration of mesenteric and visceral ischemia with reduction in:

i. acidosis

ii. gut bacteria translocation/sepsis;

iii. renal failure/use of renal replacement therapy.

5) Less blood loss/reduced transfusion requirement.

6) More patients can be treated where some comorbidities previously excluded them.

Page 11: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Surgical steps

• Anesthesia : General

• Position : Supine

• Incision : Midline transperitoneal / Para-rectal retroperitoneal

• Exposure of Lt. renal , SMA, and celiac arteries.

• Then exposure of the Rt. Renal artery

• Then exposure of both CIAs

Page 12: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Visceral Hybrid Procedure

Octopus Graft

Page 13: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Gustavo S. Oderich, MD1, Bernardo C. Mendes, MD1, Peter Gloviczki, MD1,Manju Kalra, MD1, Audra A. Duncan, MD1 and Thomas C. Bower, MD1

Page 14: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative
Page 15: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

• Maximizes distal landing zone in short CIA.

Page 16: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Case 1

Page 17: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

LT CIA

Page 18: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

SMA Graft

Celiac Graft

LT Renal Graft

Page 19: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

SMA Graft

RT Renal

RT CIA

Page 20: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative
Page 21: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Case 2

Page 22: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative
Page 23: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Case 3

Page 24: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

LT CIA

SMA graft

LT Renal

Page 25: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

RT CIA

RT Renal

Page 26: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative
Page 27: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

We are still collecting our data about hybrid procedures but the preliminary results :

• No: 14

• Mortality: 7%

• Paraplegia: 0%

• Endoleak: 7%

• Graft patency: 93%

Page 28: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative
Page 29: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Systematic review & Meta-analysis

Bakoyiannis et al(2009)

Moulakakis et al (2011)

No of patients

108 / 15 507 / 19

30 days mortality

10% 12%

paraplegia 3% 4.5%

Endoleak 20% 22%

Graft patency

97% 96%

Bakoyiannis et al. Hybrid procedures in the treatment of thoracoabdominal aortic aneurysms: a

systematic review. J Endovasc Ther. 2009;16:443-450.

Moulakakis et al. Hybrid open endovascular technique for aortic thoracoabdominal pathologies.

Circulation. 2011;124:2670-2680.

Page 30: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

North American Complex Abdominal Aortic Debranching Registry (2011)

• 208 patients / 14 academic center

• 163 TAAA / 45 pararenal aneurysms.

• 30 days mortality: 14% (16% TAAA, 9% pararenal)

• Paraplegia: 10%

• Endoleak: 13%

• Graft patency: primary 90% / 1 year 85%.

Page 31: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative
Page 32: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative

Conclousion

• Hybrid repair may offer a viable alternative for patients atslightly higher than average operative risk, or for those who haveisolated high risk comorbidities (i.e. chronic lung disease).

• Hybrid surgery will always remain a method of treating thiscomplex and life-threatening disease particularly in individualswith unfavorable anatomy.

• Hybrid repair should be considered in patient with complex aorticaneurysm who are unsuitable to endovascular repair or incenters who have difficulty accessing FBSG.

Page 33: Visceral debranching and stenting (hybrid) for complex AAA ... · Conclousion •Hybrid repair may offer a viable alternative for patients at slightly higher than average operative